BMP-2 decreases Mash1 stability by increasing Id1 expression

EMBO Journal

Volumn 23, Issue 17, 2004, Pages 3527-3537

  Viñals, Francesc ^a   Reiriz, Julia ^a   Ambrosio, Santiago ^a   Bartrons, Ramon ^a   Rosa, Jose Luis ^a   Ventura, Francesc ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

BMP; Cell differentiation; Helix loop helix transcription factors; Id1; Mash1

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; HELIX LOOP HELIX PROTEIN; INHIBITOR OF DIFFERENTIATION 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MASH1; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BONE MORPHOGENETIC PROTEINS; CASEIN KINASE II; CELL LINE, TUMOR; DNA-BINDING PROTEINS; DRUG STABILITY; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEIN 1; MICE; MODELS, BIOLOGICAL; NEUROSECRETORY SYSTEMS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; RNA PROCESSING, POST-TRANSCRIPTIONAL; SERINE; SIGNAL TRANSDUCTION; TCF TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 4644294109     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600360     Document Type: Article

References (52)

1. Abdallah B, Hassan A, Benoist C, Goula D, Behr JP, Demeneix BA (1996) A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine. Hum Gene Ther 7: 1947-1954
2. Borges M, Linnoila RI, van de Velde HJ, Chen H, Nelkin BD, Mabry M, Baylin SB, Ball DW (1997) An achaete-scute homologue essential for neuroendocrine differentiation in the lung. Nature 386: 852-855
3. Bounpheng MA, Dimas JJ, Dodds SG, Christy BA (1999) Degradation of Id proteins by the ubiquitin-proteasome pathway. FASEB J 13: 2257-2264
4. Brosenitsch TA, Katz DM (2002) Expression of Phox2 transcription factors and induction of the dopaminergic phenotype in primary sensory neurons. Mol Cell Neurosci 20: 447-457
5. Cai L, Morrow EM, Cepko CL (2000) Misexpression of basic helix-loop-helix genes in the murine cerebral cortex affects cell fate choices and neuronal survival. Development 127: 3021-3030
6. Casarosa S, Fode C, Guillemot F (1999) Mash1 regulates neurogenesis in the ventral telencephalon. Development 126: 525-534
7. Chalaux E, López-Rovira T, Rosa JL, Bartrons R, Ventura F (1998) JunB is involved in the inhibition of myogenic differentiation by bone morphogenetic protein-2. J Biol Chem 273: 537-543
8. Chambard JC, Pognonec P (1998) A reliable way of obtaining stable inducible clones. Nucleic Acids Res 26: 3443-3444
9. Chavali GB, Vijayalakshmi C, Salunke DM (2001) Analysis of sequence signature defining functional specificity and structural stability in helix-loop-helix proteins. Proteins 42: 471-480
10. Derynck R, Zhang YE (2003) Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature 425: 577-584
11. Floyd ZE, Trausch-Azar JS, Reinstein E, Ciechanover A, Schwartz AL (2001) The nuclear ubiquitin-proteasome system degrades MyoD. J Biol Chem 276: 22468-22475
12. Gross RE, Mehler MF, Mabie PC, Zang Z, Santschi L, Kessler JA (1996) Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells. Neuron 17: 595-606
13. Gómez-Santos C, Ambrosio S, Ventura F, Ferrer I, Reiriz J (2002) TGF-beta1 increases tyrosine hydroxylase expression by a mechanism blocked by BMP-2 in human neuroblastoma SH-SY5Y cells. Brain Res 958: 152-160
14. Guillemot F, Lo LC, Johnson JE, Auerbach A, Anderson DJ, Joyner AL (1993) Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell 75: 463-476
15. Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H (2000) Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development 127: 3913-3921
16. Jen Y, Manova K, Benezra R (1997) Each member of the Id gene family exhibits a unique expression pattern in mouse gastrulation and neurogenesis. Dev Dyn 208: 92-106
17. Jögi A, Persson P, Grynfeld A, Pahlman S, Axelson H (2002) Modulation of basic helix-loop-helix transcription complex formation by Id proteins during neuronal differentiation. J Biol Chem 277: 9118-9126
18. Kato T, Delhase M, Hoffmann A, Karin M (2003) CK2 is a C-terminal IκB kinase responsible for NF-κB activation during UV response. Mol Cell 12: 829-839
19. Kee BL, Rivera RR, Murre C (2001) Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-beta. Nat Immunol 2: 242-247
20. Kondo T, Raff M (2000) The Id4 HLH protein and the timing of oligodendrocyte differentiation. EMBO J 19: 1998-2007
21. Lee JL (1997) Basic helix-loop-helix genes in neural development. Curr Opin Neurobiol 7: 13-20
22. Lim DA, Tramontin AD, Trevejo JM, Herrera DG, Garcia-Verdugo JM, Alvarez-Buylla A (2000) Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron 28: 713-726
23. Linnoila RI, Zhao B, De Mayo JL, Nelkin BD, Baylin SB, De Mayo FJ, Ball DW (2000) Constitutive achaete-scute homologue-1 promotes airway dysplasia and lung neuroendocrine tumors in transgenic mice. Cancer Res 60: 4005-4009
24. Litchfield DW (2003) Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem J 369: 1-15
25. Lo L, Johnson JE, Wuenschell CW, Saito T, Anderson DJ (1991) Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells. Genes Dev 9: 1524-1537
26. Lo L, Morin X, Brunet JF, Anderson DJ (1999) Specification of neurotransmitter identity by Phox2 proteins in neural crest stem cells. Neuron 22: 693-705
27. Lo L, Tiveron MC, Anderson DJ (1998) MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity. Development 125: 609-620
28. López-Rovira T, Chalaux E, Massagué J, Rosa JL, Ventura F (2002) Direct binding of Smad1 and Smad4 to two distinct motifs mediates bone morphogenetic protein-specific transcriptional activation of Id1 gene. J Biol Chem 277: 3176-3185
29. Lyden D, Young AZ, Zagzag D, Yan W, Gerald W, O'Reilly R, Bader BL, Hynes RO, Zhuang Y, Manova K, Benezra R (1999) Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. Nature 401: 670-677
30. Meggio F, Pinna LA (2003) One-thousand-and-one substrates of protein kinase CK2? FASEB J 17: 349-368
31. Mehler MF, Mabie PC, Zhang D, Kessler JA (1997) Bone morphogenetic proteins in the nervous system. Trends Neurosci 20: 309-317
32. Nakashima K, Takizawa T, Ochiai W, Yanagisawa M, Hisatsune T, Nakafuku M, Miyazono K, Kishimoto T, Kageyama R, Taga T (2001) BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis. Proc Natl Acad Sci USA 98: 5868-5873
33. Nakashima K, Yanagisawa M, Arakawa H, Kimura N, Hisatsune T, Kawabata M, Miyazono K, Taga T (1999) Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science 284: 479-482
34. Norton JD (2000) ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis. J Cell Sci 113: 3897-3905
35. Norton JD, Deed RW, Craggs G, Sablitzky F (1998) Id helix-loop-helix proteins in cell growth and differentiation. Trends Cell Biol 8: 58-65
36. Rawls A, Olson EN (1997) MyoD meets its maker. Cell 89: 5-8
37. Ross SE, Greenberg ME, Stiles CD (2003) Basic helix-loop-helix factors in cortical development. Neuron 39: 13-25
38. Sarno S, Moro S, Meggio F, Zagotto G, Dal Ben D, Ghisellini P, Battistutta R, Zanotti G, Pinna LA (2002) Toward the rational design of protein kinase casein kinase-2 inhibitors. Pharmacol Ther 93: 159-168
39. Shah NM, Groves AK, Anderson DJ (1996) Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members. Cell 85: 331-343
40. Shi Y, Massagué J (2003) Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685-700
41. Shou J, Rim PC, Calof AL (1999) BMPs inhibit neurogenesis by a mechanism involving degradation of a transcription factor. Nat Neurosci 2: 339-345
42. Song A, Wang Q, Goebl MG, Harrington MA (1998) Phosphorylation of nuclear MyoD is required for its rapid degradation. Mol Cell Biol 18: 4994-4999
43. Spits H, Couwenberg F, Bakker AQ, Weijer K, Uittenbogaart CH (2000) Id2 and Id3 inhibit development of CD34(+) stem cells into predendritic cell (pre-DC)2 but not into pre-DC1. J Exp Med 192: 1775-1783
44. Sriuranpong V, Borges MW, Strock CL, Nakakura EK, Watkins DN, Blaumueller CM, Nelkin BD, Ball DW (2002) Notch signaling induces rapid degradation of achaete-scute homolog 1. Mol Cell Biol 22: 3129-3139
45. Sun XH (1994) Constitutive expression of the Id1 gene impairs mouse B cell development. Cell 79: 893-900
46. Suzuki T, Yamakuni T, Hagiwara M, Ichinose H (2002) Identification of ATF-2 as a transcriptional regulator for the tyrosine hydroxylase gene. J Biol Chem 277: 40768-40774
47. ten Dijke P, Miyazono K, Heldin CH (2000) Signaling inputs converge on nuclear effectors in TGF-beta signaling. Trends Biochem Sci 25: 64-70
48. Treier M, Staszewski LM, Bohmann D (1994) Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain. Cell 78: 787-798
49. Ventura F, Doody J, Liu F, Wrana JL, Massagué J (1994) Reconstitution and transphosphorylation of TGF-beta receptor complexes. EMBO J 13: 5581-5589
50. Voronova A, Baltimore D (1990) Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains. Proc Natl Acad Sci USA 87: 4722-4726
51. Wilson PA, Hemmati-Brivanlou A (1995) Induction of epidermis and inhibition of neural fate by BMP-4. Nature 376: 331-336
52. Ying Q-L, Nichols J, Chambers I, Smith A (2003) BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115: 281-292