Regulation of neurogenin stability by ubiquitin-mediated proteolysis

Biochemical Journal

Volumn 407, Issue 2, 2007, Pages 277-284

  Vosper, Jonathan M D ^a   Fiore Heriche, Christelle S ^a   Horan, Ian ^a   Wilson, Kate ^a   Wise, Helen ^a   Philpott, Anna ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Neurogenin; Polyubiquitination; Protein stability; Ubiquitin proteasome system; Xenopus neuronal differentiation

Indexed keywords

NEUROGENIN; POLYUBIQUITINATION; PROTEIN STABILITY; UBIQUITIN-PROTEASOME SYSTEM; XENOPUS NEURONAL DIFFERENTIATION;

BINDING SITES; MAMMALS; NEUROLOGY; PHOSPHORYLATION;

TRANSCRIPTION FACTORS;

DNA; NEUROGENIN; PROTEASOME; PROTEIN; THREONINE; UBIQUITIN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYONAL CARCINOMA; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; XENOPUS;

ANIMALS; CELL LINE, TUMOR; MICE; NERVE TISSUE PROTEINS; PEPTIDE HYDROLASES; PHOSPHORYLATION; PROTEIN BINDING; TCF TRANSCRIPTION FACTORS; UBIQUITIN; XENOPUS;

MAMMALIA;

EID: 35048837492     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20070064     Document Type: Article

References (32)

1. Bertrand, N., Castro, D. S. and Guillemot, F. (2002) Proneural genes and the specification of neural cell types. Nat. Rev. Neurosci. 3, 517-530
2. Furlong, R. F. and Graham, A. (2005) Vertebrate neurogenin evolution: long-term maintenance of redundant duplicates. Dev. Genes Evol. 215, 639-644
3. Ross, S. E., Greenberg, M. E. and Stiles, C. D. (2003) Basic helix-loop-helix factors in cortical development. Neuron 39, 13-25
4. Ma, Q., Kintner, C. and Anderson, D. J. (1996) Identification of neurogenin, a vertebrate neuronal determination gene. Cell 87, 43-52
5. Xic1 is required for differentiation of primary neurones in Xenopus. Development 130, 85-92
6. kip1 independently promotes neuronal differentiation and migration in the cerebral cortex. Genes Dev. 20, 1511-1524
7. Nandi, D., Tahiliani, P., Kumar, A. and Chandu, D. (2006) The ubiquitin-proteasome system. J. Biosci. 31, 137-155
8. Song, A., Wang, Q., Goebl, M. G. and Harrington, M. A. (1998) Phosphorylation of nuclear MyoD is required for its rapid degradation. Mol. Cell. Biol. 18, 4994-4999
9. Bounpheng, M. A., Dimas, J. J., Dodds, S. G. and Christy, B. A. (1999) Degradation of Id proteins by the ubiquitin-proteasome pathway. FASEB J. 13, 2257-2264
10. Shou, J., Rim, P. C. and Calof, A. L. (1999) BMPs inhibit neurogenesis by a mechanism involving degradation of a transcription factor. Nat. Neurosci. 2, 339-345
11. Vinals, F., Reiriz, J., Ambrosio, S., Bartrons, R., Rosa, J. L. and Ventura, F. (2004) BMP-2 decreases Mash1 stability by increasing Id1 expression. EMBO J. 23, 3527-3537
12. Lee, J. E., Hollenberg, S. M., Snider, L., Turner, D. L., Lipnick, N. and Weintraub, H. (1995) Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 268, 836-844
13. Komuro, A., Imamura, T., Saitoh, M., Yoshida, Y., Yamori, T., Miyazono, K. and Miyazawa, K. (2004) Negative regulation of transforming growth factor-β (TGF-β) signaling by WW domain-containing protein 1 (WWP1). Oncogene 23, 6914-6923
14. Rashbass, J., Taylor, M. V. and Gurdon, J. B. (1992) The DNA-binding protein E12 co-operates with XMyoD in the activation of muscle-specific gene expression in Xenopus embryos. EMBO J. 11, 2981-2990
15. Sun, X. H. and Baltimore, D. (1991) An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers. Cell 64, 459-470
16. Nieuwkoop, P. D. and Faber, J. (1967) Normal Table of Xenopus laevis (Daudin), North Holland Publishing, Amsterdam
17. Murray, A. W. (1991) Cell cycle extracts. Methods Cell Biol. 36, 581-605
18. Glotzer, M., Murray, A. W. and Kirschner, M. W. (1991) Cyclin is degraded by the ubiquitin pathway. Nature 349, 132-138
19. Salic, A., Lee, E., Mayer, L. and Kirschner, M. W. (2000) Control of β-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts. Mol. Cell 5, 523-532
20. Rudnicki, M. A. and McBurney, M. W. (1987) Cell culture methods and induction of differentiation of embryocarcinoma cells. In Teratocarcinomas and Embryonic Stem Cells (Robertson, E. J., ed.), pp. 19-49, IRL Press, Oxford
21. Hershko, A., Ganoth, D., Pehrson, J., Palazzo, R. E. and Cohen, L. H. (1991) Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts. J. Biol. Chem. 266, 16376-16379
22. Ciechanover, A., Orian, A. and Schwartz, A. L. (2000) Ubiquitin-mediated proteolysis: biological regulation via destruction. BioEssays 22, 442-451
23. Kho, C. J., Huggins, G. S., Endege, W. O., Hsieh, C. M., Lee, M. E. and Haber, E. (1997) Degradation of E2A proteins through a ubiquitin-conjugating enzyme, UbcE2A. J. Biol. Chem. 272, 3845-3851
24. Doucet, C., Gutierrez, G. J., Lindon, C., Lorca, T., Lledo, G., Pinset, C. and Coux, O. (2005) Multiple phosphorylation events control mitotic degradation of the muscle transcription factor Myf5. BMC Biochem. 6, 27
25. Tintignac, L. A., Leibovitch, M. P., Kitzmann, M., Fernandez, A., Ducommun, B., Meijer, L. and Leibovitch, S. A. (2000) Cyclin E-cdk2 phosphorylation promotes late G1-phase degradation of MyoD in muscle cells. Exp. Cell Res. 259, 300-307
26. Farah, M. H., Olson, J. M., Sucic, H. B., Hume, R. I., Tapscott, S. J. and Turner, D. L. (2000) Generation of neurons by transient expression of neural bHLH proteins in mammalian cells. Development 127, 693-702
27. Collins, G. A. and Tansey, W. P. (2006) The proteasome: a utility tool for transcription? Curr. Opin. Genet. Dev. 16, 197-202
28. Breitschopf, K., Bengal, E., Ziv, T., Admon, A. and Ciechanover, A. (1998) A novel site for ubiquitination: the N-terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein. EMBO J. 17, 5964-5973
29. Yeo, W. and Gautier, J. (2005) XNGNR1-dependent neurogenesis mediates early neural cell death. Mech. Dev. 122, 635-644
30. Nie, L., Xu, M., Vladimirova, A. and Sun, X. H. (2003) Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities. EMBO J. 22, 5780-5792
31. Lindon, C., Albagli, O., Domeyne, P., Montarras, D. and Pinset, C. (2000) Constitutive instability of muscle regulatory factor Myf5 is distinct from its mitosis-specific disappearance, which requires a D-box-like motif overlapping the basic domain. Mol. Cell. Biol. 20, 8923-8932
32. Hofstetter, C. P., Holmstrom, N. A., Lilja, J. A., Schweinhardt, P., Hao, J., Spenger, C., Wiesenfeld-Hallin, Z., Kurpad, S. N., Frisen, J. and Olson, L. (2005) Allodynia limits the usefulness of intraspinal neural stem cell grafts; directed differentiation improves outcome. Nat. Neurosci. 8, 346-353