-
1
-
-
49649084735
-
Nuclear receptors, mitochondria and lipid metabolism
-
Alaynick W.A. Nuclear receptors, mitochondria and lipid metabolism. Mitochondrion 2008, 8:329-337.
-
(2008)
Mitochondrion
, vol.8
, pp. 329-337
-
-
Alaynick, W.A.1
-
2
-
-
0037008686
-
Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line
-
Arico S., Pattingre S., Bauvy C., Gane P., Barbat A., Codogno P., Ogier-Denis E. Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line. J. Biol. Chem. 2002, 277:27613-27621.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27613-27621
-
-
Arico, S.1
Pattingre, S.2
Bauvy, C.3
Gane, P.4
Barbat, A.5
Codogno, P.6
Ogier-Denis, E.7
-
3
-
-
0032910169
-
Apoptosis control by death and decoy receptors
-
Ashkenazi A., Dixit V.M. Apoptosis control by death and decoy receptors. Curr. Opin. Cell Biol. 1999, 11:255-260.
-
(1999)
Curr. Opin. Cell Biol.
, vol.11
, pp. 255-260
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
4
-
-
0030023776
-
Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling
-
Avis I.M., Jett M., Boyle T., Vos M.D., Moody T., Treston A.M., Martinez A., Mulshine J.L. Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling. J. Clin. Invest. 1996, 97:806-813.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 806-813
-
-
Avis, I.M.1
Jett, M.2
Boyle, T.3
Vos, M.D.4
Moody, T.5
Treston, A.M.6
Martinez, A.7
Mulshine, J.L.8
-
5
-
-
0035458615
-
Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions
-
Avis I., Hong S.H., Martinez A., Moody T., Choi Y.H., Trepel J., Das R., Jett M., Mulshine J.L. Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions. FASEB J. 2001, 15:2007-2009.
-
(2001)
FASEB J.
, vol.15
, pp. 2007-2009
-
-
Avis, I.1
Hong, S.H.2
Martinez, A.3
Moody, T.4
Choi, Y.H.5
Trepel, J.6
Das, R.7
Jett, M.8
Mulshine, J.L.9
-
6
-
-
56449095449
-
Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis
-
Babaev V.R., Chew J.D., Ding L., Davis S., Breyer M.D., Breyer R.M., Oates J.A., Fazio S., Linton M.F. Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis. Cell Metab. 2008, 8:492-501.
-
(2008)
Cell Metab.
, vol.8
, pp. 492-501
-
-
Babaev, V.R.1
Chew, J.D.2
Ding, L.3
Davis, S.4
Breyer, M.D.5
Breyer, R.M.6
Oates, J.A.7
Fazio, S.8
Linton, M.F.9
-
7
-
-
13544268334
-
15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer
-
Backlund M.G., Mann J.R., Holla V.R., Buchanan F.G., Tai H.-H., Musiek E.S., Milne G.L., Katkuri S., DuBois R.N. 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer. J. Biol. Chem. 2005, 280:3217-3223.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 3217-3223
-
-
Backlund, M.G.1
Mann, J.R.2
Holla, V.R.3
Buchanan, F.G.4
Tai, H.-H.5
Musiek, E.S.6
Milne, G.L.7
Katkuri, S.8
DuBois, R.N.9
-
8
-
-
0033546190
-
Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2
-
Bishop-Bailey D., Hla T. Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2. J. Biol. Chem. 1999, 274:17042-17048.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17042-17048
-
-
Bishop-Bailey, D.1
Hla, T.2
-
9
-
-
0026702580
-
Differential expression of arachidonate 5-lipoxygenase transcripts in human brain tumors: evidence for the expression of a multitranscript family
-
Boado R.J., Pardridge W.M., Vinters H.V., Black K.L. Differential expression of arachidonate 5-lipoxygenase transcripts in human brain tumors: evidence for the expression of a multitranscript family. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:9044-9048.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 9044-9048
-
-
Boado, R.J.1
Pardridge, W.M.2
Vinters, H.V.3
Black, K.L.4
-
10
-
-
0037592926
-
Levuglandinyl adducts of proteins are formed via a prostaglandin H2 synthase-dependent pathway after platelet activation
-
Boutaud O., Li J., Zagol I., Shipp E.A., Davies S.S., Roberts L.J., Oates J.A. Levuglandinyl adducts of proteins are formed via a prostaglandin H2 synthase-dependent pathway after platelet activation. J. Biol. Chem. 2003, 278:16926-16928.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16926-16928
-
-
Boutaud, O.1
Li, J.2
Zagol, I.3
Shipp, E.A.4
Davies, S.S.5
Roberts, L.J.6
Oates, J.A.7
-
11
-
-
17444365094
-
Cyclooxygenase-dependent lipid-modification of brain proteins
-
Boutaud O., Andreasson K.I., Zagol-Ikapitte I., Oates J.A. Cyclooxygenase-dependent lipid-modification of brain proteins. Brain Pathol. 2005, 15:139-142.
-
(2005)
Brain Pathol.
, vol.15
, pp. 139-142
-
-
Boutaud, O.1
Andreasson, K.I.2
Zagol-Ikapitte, I.3
Oates, J.A.4
-
12
-
-
0033588022
-
Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate
-
Brash A.R. Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate. J. Biol. Chem. 1999, 274:23679-23682.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23679-23682
-
-
Brash, A.R.1
-
14
-
-
0034991805
-
Prostaglandin EP(1) receptor subtype selectivity takes shape
-
Breyer R.M. Prostaglandin EP(1) receptor subtype selectivity takes shape. Mol. Pharmacol. 2001, 59:1357-1359.
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 1357-1359
-
-
Breyer, R.M.1
-
15
-
-
0035042253
-
Prostanoid receptors: subtypes and signaling
-
Breyer R.M., Bagdassarian C.K., Myers S.A., Breyer M.D. Prostanoid receptors: subtypes and signaling. Annu. Rev. Pharmacol. Toxicol. 2001, 41:661-690.
-
(2001)
Annu. Rev. Pharmacol. Toxicol.
, vol.41
, pp. 661-690
-
-
Breyer, R.M.1
Bagdassarian, C.K.2
Myers, S.A.3
Breyer, M.D.4
-
16
-
-
84055190408
-
Affirmative effects of iloprost on apoptosis during ischemia-reperfusion injury in kidney as a distant organ
-
Canacankatan N., Sucu N., Aytacoglu B., Gul O.E., Gorur A., Korkmaz B., Sahan-Firat S., Antmen E.S., Tamer L., Ayaz L., Vezir O., Kanik A., Tunctan B. Affirmative effects of iloprost on apoptosis during ischemia-reperfusion injury in kidney as a distant organ. Ren. Fail. 2012, 34:111-118.
-
(2012)
Ren. Fail.
, vol.34
, pp. 111-118
-
-
Canacankatan, N.1
Sucu, N.2
Aytacoglu, B.3
Gul, O.E.4
Gorur, A.5
Korkmaz, B.6
Sahan-Firat, S.7
Antmen, E.S.8
Tamer, L.9
Ayaz, L.10
Vezir, O.11
Kanik, A.12
Tunctan, B.13
-
17
-
-
77649337228
-
The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer
-
Cathcart M.-C., Reynolds J.V., O'Byrne K.J., Pidgeon G.P. The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer. Biochim. Biophys. Acta, Rev. Cancer 2010, 1805:153-166.
-
(2010)
Biochim. Biophys. Acta, Rev. Cancer
, vol.1805
, pp. 153-166
-
-
Cathcart, M.-C.1
Reynolds, J.V.2
O'Byrne, K.J.3
Pidgeon, G.P.4
-
18
-
-
79952328452
-
Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer
-
Cathcart M.C., Gately K., Cummins R., Kay E., O'Byrne K.J., Pidgeon G.P. Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer. Mol. Cancer 2011, 10:25.
-
(2011)
Mol. Cancer
, vol.10
, pp. 25
-
-
Cathcart, M.C.1
Gately, K.2
Cummins, R.3
Kay, E.4
O'Byrne, K.J.5
Pidgeon, G.P.6
-
19
-
-
78651429337
-
L-carnitine reduces doxorubicin-induced apoptosis through a prostacyclin-mediated pathway in neonatal rat cardiomyocytes
-
Chao H.-H., Liu J.-C., Hong H.-J., Lin J.-w, Chen C.-H., Cheng T.-H. L-carnitine reduces doxorubicin-induced apoptosis through a prostacyclin-mediated pathway in neonatal rat cardiomyocytes. Int. J. Cardiol. 2011, 146:145-152.
-
(2011)
Int. J. Cardiol.
, vol.146
, pp. 145-152
-
-
Chao, H.-H.1
Liu, J.-C.2
Hong, H.-J.3
Lin, J.-W.4
Chen, C.-H.5
Cheng, T.-H.6
-
20
-
-
23644451669
-
Lipid signaling: sleep, synaptic plasticity, and neuroprotection
-
Chen C., Bazan N.G. Lipid signaling: sleep, synaptic plasticity, and neuroprotection. Prostaglandins Other Lipid Mediat. 2005, 77:65-76.
-
(2005)
Prostaglandins Other Lipid Mediat.
, vol.77
, pp. 65-76
-
-
Chen, C.1
Bazan, N.G.2
-
21
-
-
0035725998
-
Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis
-
Chen J.K., Capdevila J., Harris R.C. Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis. Mol. Cell. Biol. 2001, 21:6322-6331.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6322-6331
-
-
Chen, J.K.1
Capdevila, J.2
Harris, R.C.3
-
22
-
-
33645006216
-
Increased thromboxane B(2) levels are associated with lipid peroxidation and Bcl-2 expression in human lung carcinoma
-
Chen G.G., Lee T.W., Yip J.H., Xu H., Lee I.K., Mok T.S., Warner T.D., Yim A.P. Increased thromboxane B(2) levels are associated with lipid peroxidation and Bcl-2 expression in human lung carcinoma. Cancer Lett. 2006, 234:193-198.
-
(2006)
Cancer Lett.
, vol.234
, pp. 193-198
-
-
Chen, G.G.1
Lee, T.W.2
Yip, J.H.3
Xu, H.4
Lee, I.K.5
Mok, T.S.6
Warner, T.D.7
Yim, A.P.8
-
23
-
-
66749159294
-
Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo
-
Chen C., Li G., Liao W., Wu J., Liu L., Ma D., Zhou J., Elbekai R.H., Edin M.L., Zeldin D.C., Wang D.W. Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo. J. Pharmacol. Exp. Ther. 2009, 329:908-918.
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.329
, pp. 908-918
-
-
Chen, C.1
Li, G.2
Liao, W.3
Wu, J.4
Liu, L.5
Ma, D.6
Zhou, J.7
Elbekai, R.H.8
Edin, M.L.9
Zeldin, D.C.10
Wang, D.W.11
-
24
-
-
76049083966
-
Reactive oxygen species, cellular redox systems, and apoptosis
-
Circu M.L., Aw T.Y. Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic. Biol. Med. 2010, 48:749-762.
-
(2010)
Free Radic. Biol. Med.
, vol.48
, pp. 749-762
-
-
Circu, M.L.1
Aw, T.Y.2
-
26
-
-
39049094254
-
Regulation of cell proliferation and apoptosis by bioactive lipid mediators
-
Claria J. Regulation of cell proliferation and apoptosis by bioactive lipid mediators. Recent Pat. Anticancer Drug Discov. 2006, 1:369-382.
-
(2006)
Recent Pat. Anticancer Drug Discov.
, vol.1
, pp. 369-382
-
-
Claria, J.1
-
27
-
-
0032884254
-
Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells
-
Clay C.E., Namen A.M., Atsumi G., Willingham M.C., High K.P., Kute T.E., Trimboli A.J., Fonteh A.N., Dawson P.A., Chilton F.H. Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells. Carcinogenesis 1999, 20:1905-1911.
-
(1999)
Carcinogenesis
, vol.20
, pp. 1905-1911
-
-
Clay, C.E.1
Namen, A.M.2
Atsumi, G.3
Willingham, M.C.4
High, K.P.5
Kute, T.E.6
Trimboli, A.J.7
Fonteh, A.N.8
Dawson, P.A.9
Chilton, F.H.10
-
28
-
-
0033153192
-
The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP
-
Datta K., Biswal S.S., Kehrer J.P. The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP. Biochem. J. 1999, 340(Pt 2):371-375.
-
(1999)
Biochem. J.
, vol.340
, Issue.PART 2
, pp. 371-375
-
-
Datta, K.1
Biswal, S.S.2
Kehrer, J.P.3
-
29
-
-
0026529332
-
Cloning and expression of an airway epithelial 12-lipoxygenase
-
De Marzo N., Sloane D.L., Dicharry S., Highland E., Sigal E. Cloning and expression of an airway epithelial 12-lipoxygenase. Am. J. Physiol. 1992, 262:L198-L207.
-
(1992)
Am. J. Physiol.
, vol.262
-
-
De Marzo, N.1
Sloane, D.L.2
Dicharry, S.3
Highland, E.4
Sigal, E.5
-
30
-
-
34547131815
-
Cross-talks between cyclooxygenase-2 and tumor suppressor protein p53: balancing life and death during inflammatory stress and carcinogenesis
-
de Moraes E., Dar N.A., de Moura Gallo C.V., Hainaut P. Cross-talks between cyclooxygenase-2 and tumor suppressor protein p53: balancing life and death during inflammatory stress and carcinogenesis. Int. J. Cancer 2007, 121:929-937.
-
(2007)
Int. J. Cancer
, vol.121
, pp. 929-937
-
-
de Moraes, E.1
Dar, N.A.2
de Moura Gallo, C.V.3
Hainaut, P.4
-
31
-
-
33746790148
-
Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature
-
Dhanasekaran A., Al-Saghir R., Lopez B., Zhu D., Gutterman D.D., Jacobs E.R., Medhora M. Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature. Am. J. Physiol. Heart Circ. Physiol. 2006, 291:H517-H531.
-
(2006)
Am. J. Physiol. Heart Circ. Physiol.
, vol.291
-
-
Dhanasekaran, A.1
Al-Saghir, R.2
Lopez, B.3
Zhu, D.4
Gutterman, D.D.5
Jacobs, E.R.6
Medhora, M.7
-
32
-
-
39149128273
-
Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia
-
Dhanasekaran A., Gruenloh S.K., Buonaccorsi J.N., Zhang R., Gross G.J., Falck J.R., Patel P.K., Jacobs E.R., Medhora M. Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia. Am. J. Physiol. Heart Circ. Physiol. 2008, 294:H724-H735.
-
(2008)
Am. J. Physiol. Heart Circ. Physiol.
, vol.294
-
-
Dhanasekaran, A.1
Gruenloh, S.K.2
Buonaccorsi, J.N.3
Zhang, R.4
Gross, G.J.5
Falck, J.R.6
Patel, P.K.7
Jacobs, E.R.8
Medhora, M.9
-
33
-
-
76549096602
-
Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12,14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms
-
Diers A.R., Higdon A.N., Ricart K.C., Johnson M.S., Agarwal A., Kalyanaraman B., Landar A., Darley-Usmar V.M. Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12,14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms. Biochem. J. 2010, 426:31-41.
-
(2010)
Biochem. J.
, vol.426
, pp. 31-41
-
-
Diers, A.R.1
Higdon, A.N.2
Ricart, K.C.3
Johnson, M.S.4
Agarwal, A.5
Kalyanaraman, B.6
Landar, A.7
Darley-Usmar, V.M.8
-
34
-
-
47349086201
-
PPARγ and apoptosis in cancer
-
Elrod H.A., Sun S.-Y. PPARγ and apoptosis in cancer. PPAR Res. 2008, 2008.
-
(2008)
PPAR Res.
, vol.2008
-
-
Elrod, H.A.1
Sun, S.-Y.2
-
35
-
-
1542345746
-
The biphasic effects of cyclopentenone prostaglandins, prostaglandin J(2) and 15-deoxy-Delta(12,14)-prostaglandin J(2) on proliferation and apoptosis in rat basophilic leukemia (RBL-2H3) cells
-
Emi M., Maeyama K. The biphasic effects of cyclopentenone prostaglandins, prostaglandin J(2) and 15-deoxy-Delta(12,14)-prostaglandin J(2) on proliferation and apoptosis in rat basophilic leukemia (RBL-2H3) cells. Biochem. Pharmacol. 2004, 67:1259-1267.
-
(2004)
Biochem. Pharmacol.
, vol.67
, pp. 1259-1267
-
-
Emi, M.1
Maeyama, K.2
-
36
-
-
33748697633
-
Prostaglandin-induced programmed cell death in Trypanosoma brucei involves oxidative stress
-
Figarella K., Uzcategui N.L., Beck A., Schoenfeld C., Kubata B.K., Lang F., Duszenko M. Prostaglandin-induced programmed cell death in Trypanosoma brucei involves oxidative stress. Cell Death Differ. 2006, 13:1802-1814.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1802-1814
-
-
Figarella, K.1
Uzcategui, N.L.2
Beck, A.3
Schoenfeld, C.4
Kubata, B.K.5
Lang, F.6
Duszenko, M.7
-
37
-
-
0042734625
-
Prostanoid receptors and phosphatidylinositol 3-kinase: a pathway to cancer?
-
Fujino H., Regan J.W. Prostanoid receptors and phosphatidylinositol 3-kinase: a pathway to cancer?. Trends Pharmacol. Sci. 2003, 24:335-340.
-
(2003)
Trends Pharmacol. Sci.
, vol.24
, pp. 335-340
-
-
Fujino, H.1
Regan, J.W.2
-
38
-
-
0035976575
-
Prostaglandins and leukotrienes: advances in eicosanoid biology
-
Funk C.D. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 2001, 294:1871-1875.
-
(2001)
Science
, vol.294
, pp. 1871-1875
-
-
Funk, C.D.1
-
39
-
-
0025299409
-
Molecular cloning, primary structure, and expression of the human platelet/erythroleukemia cell 12-lipoxygenase
-
Funk C.D., Furci L., FitzGerald G.A. Molecular cloning, primary structure, and expression of the human platelet/erythroleukemia cell 12-lipoxygenase. Proc. Natl. Acad. Sci. U. S. A. 1990, 87:5638-5642.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 5638-5642
-
-
Funk, C.D.1
Furci, L.2
FitzGerald, G.A.3
-
40
-
-
0036889641
-
Reactive oxygen intermediates in TNF signaling
-
Garg A.K., Aggarwal B.B. Reactive oxygen intermediates in TNF signaling. Mol. Immunol. 2002, 39:509-517.
-
(2002)
Mol. Immunol.
, vol.39
, pp. 509-517
-
-
Garg, A.K.1
Aggarwal, B.B.2
-
41
-
-
0031577170
-
Arachidonic acid stimulates prostate cancer cell growth: critical role of 5-lipoxygenase
-
Ghosh J., Myers C.E. Arachidonic acid stimulates prostate cancer cell growth: critical role of 5-lipoxygenase. Biochem. Biophys. Res. Commun. 1997, 235:418-423.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.235
, pp. 418-423
-
-
Ghosh, J.1
Myers, C.E.2
-
42
-
-
0032573175
-
Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells
-
Ghosh J., Myers C.E. Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:13182-13187.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 13182-13187
-
-
Ghosh, J.1
Myers, C.E.2
-
43
-
-
0642364442
-
Inducible cyclooxygenase-derived 15-deoxy(Delta)12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis
-
Gilroy D.W., Colville-Nash P.R., McMaster S., Sawatzky D.A., Willoughby D.A., Lawrence T. Inducible cyclooxygenase-derived 15-deoxy(Delta)12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis. FASEB J. 2003, 17:2269-2271.
-
(2003)
FASEB J.
, vol.17
, pp. 2269-2271
-
-
Gilroy, D.W.1
Colville-Nash, P.R.2
McMaster, S.3
Sawatzky, D.A.4
Willoughby, D.A.5
Lawrence, T.6
-
44
-
-
2442445450
-
Inflammatory resolution: new opportunities for drug discovery
-
Gilroy D.W., Lawrence T., Perretti M., Rossi A.G. Inflammatory resolution: new opportunities for drug discovery. Nat. Rev. Drug Discov. 2004, 3:401-416.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 401-416
-
-
Gilroy, D.W.1
Lawrence, T.2
Perretti, M.3
Rossi, A.G.4
-
45
-
-
70849134064
-
Convergence of the 5-LOX and COX-2 pathways: heme-catalyzed cleavage of the 5S-HETE-derived di-endoperoxide into aldehyde fragments
-
Griesser M., Boeglin W.E., Suzuki T., Schneider C. Convergence of the 5-LOX and COX-2 pathways: heme-catalyzed cleavage of the 5S-HETE-derived di-endoperoxide into aldehyde fragments. J. Lipid Res. 2009, 50:2455-2462.
-
(2009)
J. Lipid Res.
, vol.50
, pp. 2455-2462
-
-
Griesser, M.1
Boeglin, W.E.2
Suzuki, T.3
Schneider, C.4
-
46
-
-
79955558825
-
Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathways
-
Griesser M., Suzuki T., Tejera N., Mont S., Boeglin W.E., Pozzi A., Schneider C. Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathways. Proc. Natl. Acad. Sci. 2011, 108:6945-6950.
-
(2011)
Proc. Natl. Acad. Sci.
, vol.108
, pp. 6945-6950
-
-
Griesser, M.1
Suzuki, T.2
Tejera, N.3
Mont, S.4
Boeglin, W.E.5
Pozzi, A.6
Schneider, C.7
-
47
-
-
0035864855
-
Lipoxygenase-5 is overexpressed in prostate adenocarcinoma
-
Gupta S., Srivastava M., Ahmad N., Sakamoto K., Bostwick D.G., Mukhtar H. Lipoxygenase-5 is overexpressed in prostate adenocarcinoma. Cancer 2001, 91:737-743.
-
(2001)
Cancer
, vol.91
, pp. 737-743
-
-
Gupta, S.1
Srivastava, M.2
Ahmad, N.3
Sakamoto, K.4
Bostwick, D.G.5
Mukhtar, H.6
-
48
-
-
77951240575
-
Protection against cytokine toxicity through endoplasmic reticulum and mitochondrial stress prevention by prostacyclin synthase overexpression in insulin-producing cells
-
Gurgul-Convey E., Lenzen S. Protection against cytokine toxicity through endoplasmic reticulum and mitochondrial stress prevention by prostacyclin synthase overexpression in insulin-producing cells. J. Biol. Chem. 2010, 285:11121-11128.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 11121-11128
-
-
Gurgul-Convey, E.1
Lenzen, S.2
-
49
-
-
80054052917
-
Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease
-
Haeggström J.Z., Funk C.D. Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease. Chem. Rev. 2011, 111:5866-5898.
-
(2011)
Chem. Rev.
, vol.111
, pp. 5866-5898
-
-
Haeggström, J.Z.1
Funk, C.D.2
-
50
-
-
0014217346
-
Oxygenation of unsaturated fatty acids by the vesicular gland of sheep
-
Hamberg M., Samuelsson B. Oxygenation of unsaturated fatty acids by the vesicular gland of sheep. J. Biol. Chem. 1967, 242:5344-5354.
-
(1967)
J. Biol. Chem.
, vol.242
, pp. 5344-5354
-
-
Hamberg, M.1
Samuelsson, B.2
-
51
-
-
0021043018
-
16,16-Dimethyl prostaglandin E2 increases survival of murine intestinal stem cells when given before photon radiation
-
Hanson W.R., Thomas C. 16,16-Dimethyl prostaglandin E2 increases survival of murine intestinal stem cells when given before photon radiation. Radiat. Res. 1983, 96:393-398.
-
(1983)
Radiat. Res.
, vol.96
, pp. 393-398
-
-
Hanson, W.R.1
Thomas, C.2
-
52
-
-
0036164609
-
Prostaglandin D(2), its metabolite 15-d-PGJ(2), and peroxisome proliferator activated receptor-gamma agonists induce apoptosis in transformed, but not normal, human T lineage cells
-
Harris S.G., Phipps R.P. Prostaglandin D(2), its metabolite 15-d-PGJ(2), and peroxisome proliferator activated receptor-gamma agonists induce apoptosis in transformed, but not normal, human T lineage cells. Immunology 2002, 105:23-34.
-
(2002)
Immunology
, vol.105
, pp. 23-34
-
-
Harris, S.G.1
Phipps, R.P.2
-
53
-
-
0035824652
-
Prostacyclin-dependent apoptosis mediated by PPARδ
-
Hatae T., Wada M., Yokoyama C., Shimonishi M., Tanabe T. Prostacyclin-dependent apoptosis mediated by PPARδ. J. Biol. Chem. 2001, 276:46260-46267.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46260-46267
-
-
Hatae, T.1
Wada, M.2
Yokoyama, C.3
Shimonishi, M.4
Tanabe, T.5
-
54
-
-
34248372427
-
Prostaglandin E2-EP4 receptor signalling promotes tumorigenic behaviour of HT-29 human colorectal cancer cells
-
Hawcroft G., Ko C.W., Hull M.A. Prostaglandin E2-EP4 receptor signalling promotes tumorigenic behaviour of HT-29 human colorectal cancer cells. Oncogene 2007, 26:3006-3019.
-
(2007)
Oncogene
, vol.26
, pp. 3006-3019
-
-
Hawcroft, G.1
Ko, C.W.2
Hull, M.A.3
-
55
-
-
0036971423
-
5-Lipoxygenase and leukotriene B(4) receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissue
-
Hennig R., Ding X.Z., Tong W.G., Schneider M.B., Standop J., Friess H., Buchler M.W., Pour P.M., Adrian T.E. 5-Lipoxygenase and leukotriene B(4) receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissue. Am. J. Pathol. 2002, 161:421-428.
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 421-428
-
-
Hennig, R.1
Ding, X.Z.2
Tong, W.G.3
Schneider, M.B.4
Standop, J.5
Friess, H.6
Buchler, M.W.7
Pour, P.M.8
Adrian, T.E.9
-
56
-
-
0033135492
-
Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors
-
Hong S.H., Avis I., Vos M.D., Martinez A., Treston A.M., Mulshine J.L. Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors. Cancer Res. 1999, 59:2223-2228.
-
(1999)
Cancer Res.
, vol.59
, pp. 2223-2228
-
-
Hong, S.H.1
Avis, I.2
Vos, M.D.3
Martinez, A.4
Treston, A.M.5
Mulshine, J.L.6
-
57
-
-
0034547853
-
Contribution of cyclopentenone prostaglandins to the resolution of inflammation through the potentiation of apoptosis in activated macrophages
-
Hortelano S., Castrillo A., Alvarez A.M., Bosca L. Contribution of cyclopentenone prostaglandins to the resolution of inflammation through the potentiation of apoptosis in activated macrophages. J. Immunol. 2000, 165:6525-6531.
-
(2000)
J. Immunol.
, vol.165
, pp. 6525-6531
-
-
Hortelano, S.1
Castrillo, A.2
Alvarez, A.M.3
Bosca, L.4
-
59
-
-
39349102362
-
Prostacyclin protects renal tubular cells from gentamicin-induced apoptosis via a PPAR[alpha]-dependent pathway
-
Hsu Y.H., Chen C.H., Hou C.C., Sue Y.M., Cheng C.Y., Cheng T.H., Lin H., Tsai W.L., Chan P., Chen T.H. Prostacyclin protects renal tubular cells from gentamicin-induced apoptosis via a PPAR[alpha]-dependent pathway. Kidney Int. 2007, 73:578-587.
-
(2007)
Kidney Int.
, vol.73
, pp. 578-587
-
-
Hsu, Y.H.1
Chen, C.H.2
Hou, C.C.3
Sue, Y.M.4
Cheng, C.Y.5
Cheng, T.H.6
Lin, H.7
Tsai, W.L.8
Chan, P.9
Chen, T.H.10
-
60
-
-
35748930545
-
Blockade of tumor necrosis factor-induced Bid cleavage by caspase-resistant Rb
-
Huang X., Masselli A., Frisch S.M., Hunton I.C., Jiang Y., Wang J.Y. Blockade of tumor necrosis factor-induced Bid cleavage by caspase-resistant Rb. J. Biol. Chem. 2007, 282:29401-29413.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 29401-29413
-
-
Huang, X.1
Masselli, A.2
Frisch, S.M.3
Hunton, I.C.4
Jiang, Y.5
Wang, J.Y.6
-
61
-
-
72749127813
-
Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways
-
Huang S.K., White E.S., Wettlaufer S.H., Grifka H., Hogaboam C.M., Thannickal V.J., Horowitz J.C., Peters-Golden M. Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways. FASEB J. 2009, 23:4317-4326.
-
(2009)
FASEB J.
, vol.23
, pp. 4317-4326
-
-
Huang, S.K.1
White, E.S.2
Wettlaufer, S.H.3
Grifka, H.4
Hogaboam, C.M.5
Thannickal, V.J.6
Horowitz, J.C.7
Peters-Golden, M.8
-
62
-
-
23944460748
-
Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases
-
Imig J.D. Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases. Am. J. Physiol. Renal Physiol. 2005, 289:F496-F503.
-
(2005)
Am. J. Physiol. Renal Physiol.
, vol.289
-
-
Imig, J.D.1
-
63
-
-
70349636047
-
Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases
-
Imig J.D., Hammock B.D. Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases. Nat. Rev. Drug Discov. 2009, 8:794-805.
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 794-805
-
-
Imig, J.D.1
Hammock, B.D.2
-
64
-
-
0030028233
-
Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles
-
Imig J.D., Zou A.P., Stec D.E., Harder D.R., Falck J.R., Roman R.J. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. Am. J. Physiol. 1996, 270:R217-R227.
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Imig, J.D.1
Zou, A.P.2
Stec, D.E.3
Harder, D.R.4
Falck, J.R.5
Roman, R.J.6
-
65
-
-
0023932966
-
Inhibitory effects of prostaglandin A2 on c-myc expression and cell cycle progression in human leukemia cell line HL-60
-
Ishioka C., Kanamaru R., Sato T., Dei T., Konishi Y., Asamura M., Wakui A. Inhibitory effects of prostaglandin A2 on c-myc expression and cell cycle progression in human leukemia cell line HL-60. Cancer Res. 1988, 48:2813-2818.
-
(1988)
Cancer Res.
, vol.48
, pp. 2813-2818
-
-
Ishioka, C.1
Kanamaru, R.2
Sato, T.3
Dei, T.4
Konishi, Y.5
Asamura, M.6
Wakui, A.7
-
66
-
-
33646051204
-
Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells
-
Ivanov V.N., Hei T.K. Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells. Exp. Cell Res. 2006, 312:1401-1417.
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 1401-1417
-
-
Ivanov, V.N.1
Hei, T.K.2
-
67
-
-
0033594963
-
Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target
-
Jakobsson P.J., Thoren S., Morgenstern R., Samuelsson B. Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:7220-7225.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 7220-7225
-
-
Jakobsson, P.J.1
Thoren, S.2
Morgenstern, R.3
Samuelsson, B.4
-
68
-
-
2442633329
-
Inhibition of the arachidonic acid metabolism blocks endothelial cell migration and induces apoptosis
-
Jantke J., Ladehoff M., Kurzel F., Zapf S., Kim E., Giese A. Inhibition of the arachidonic acid metabolism blocks endothelial cell migration and induces apoptosis. Acta Neurochir. (Wien) 2004, 146:483-494.
-
(2004)
Acta Neurochir. (Wien)
, vol.146
, pp. 483-494
-
-
Jantke, J.1
Ladehoff, M.2
Kurzel, F.3
Zapf, S.4
Kim, E.5
Giese, A.6
-
69
-
-
21144459060
-
Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors
-
Jiang J.G., Chen C.L., Card J.W., Yang S., Chen J.X., Fu X.N., Ning Y.G., Xiao X., Zeldin D.C., Wang D.W. Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. Cancer Res. 2005, 65:4707-4715.
-
(2005)
Cancer Res.
, vol.65
, pp. 4707-4715
-
-
Jiang, J.G.1
Chen, C.L.2
Card, J.W.3
Yang, S.4
Chen, J.X.5
Fu, X.N.6
Ning, Y.G.7
Xiao, X.8
Zeldin, D.C.9
Wang, D.W.10
-
70
-
-
5644234190
-
Prostaglandin E2 and dexamethasone regulate eosinophil differentiation and survival through a nitric oxide- and CD95-dependent pathway
-
Jones C.P., Paula Neto H.A., Assreuy J., Vargaftig B.B., Gaspar Elsas M.I., Elsas P.X. Prostaglandin E2 and dexamethasone regulate eosinophil differentiation and survival through a nitric oxide- and CD95-dependent pathway. Nitric Oxide 2004, 11:184-193.
-
(2004)
Nitric Oxide
, vol.11
, pp. 184-193
-
-
Jones, C.P.1
Paula Neto, H.A.2
Assreuy, J.3
Vargaftig, B.B.4
Gaspar Elsas, M.I.5
Elsas, P.X.6
-
71
-
-
33947503974
-
15-deoxy-Delta(12,14)-prostaglandin J2 inhibits G2-M phase progression in human breast cancer cells via the down-regulation of cyclin B1 and survivin expression
-
Kamagata C., Tsuji N., Moriai M., Kobayashi D., Watanabe N. 15-deoxy-Delta(12,14)-prostaglandin J2 inhibits G2-M phase progression in human breast cancer cells via the down-regulation of cyclin B1 and survivin expression. Breast Cancer Res. Treat. 2007, 102:263-273.
-
(2007)
Breast Cancer Res. Treat.
, vol.102
, pp. 263-273
-
-
Kamagata, C.1
Tsuji, N.2
Moriai, M.3
Kobayashi, D.4
Watanabe, N.5
-
72
-
-
0027093272
-
A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells
-
Kargman S., Vickers P.J., Evans J.F. A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells. J. Cell Biol. 1992, 119:1701-1709.
-
(1992)
J. Cell Biol.
, vol.119
, pp. 1701-1709
-
-
Kargman, S.1
Vickers, P.J.2
Evans, J.F.3
-
73
-
-
0033783018
-
Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: correlation with Gleason staging
-
Kelavkar U.P., Cohen C., Kamitani H., Eling T.E., Badr K.F. Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: correlation with Gleason staging. Carcinogenesis 2000, 21:1777-1787.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1777-1787
-
-
Kelavkar, U.P.1
Cohen, C.2
Kamitani, H.3
Eling, T.E.4
Badr, K.F.5
-
74
-
-
0032146987
-
Bcl-2-family proteins: the role of the BH3 domain in apoptosis
-
Kelekar A., Thompson C.B. Bcl-2-family proteins: the role of the BH3 domain in apoptosis. Trends Cell Biol. 1998, 8:324-330.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 324-330
-
-
Kelekar, A.1
Thompson, C.B.2
-
75
-
-
0015117787
-
Shrinkage necrosis: a distinct mode of cellular death
-
Kerr J.F.R. Shrinkage necrosis: a distinct mode of cellular death. J. Pathol. 1971, 105:13-20.
-
(1971)
J. Pathol.
, vol.105
, pp. 13-20
-
-
Kerr, J.F.R.1
-
76
-
-
0036746162
-
Induction of apoptosis dependent on caspase activities and growth arrest in HL-60 cells by PGA2
-
Kim H.S., Rhim H., Jeong S.W., Kim J.W., Kim I.K. Induction of apoptosis dependent on caspase activities and growth arrest in HL-60 cells by PGA2. Prostaglandins Other Lipid Mediat. 2002, 70:169-183.
-
(2002)
Prostaglandins Other Lipid Mediat.
, vol.70
, pp. 169-183
-
-
Kim, H.S.1
Rhim, H.2
Jeong, S.W.3
Kim, J.W.4
Kim, I.K.5
-
77
-
-
33745745224
-
GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells
-
Kim S.H., Hwang C.I., Park W.Y., Lee J.H., Song Y.S. GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells. Carcinogenesis 2006, 27:1961-1969.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1961-1969
-
-
Kim, S.H.1
Hwang, C.I.2
Park, W.Y.3
Lee, J.H.4
Song, Y.S.5
-
78
-
-
0028883850
-
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
-
Kischkel F.C., Hellbardt S., Behrmann I., Germer M., Pawlita M., Krammer P.H., Peter M.E. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 1995, 14:5579-5588.
-
(1995)
EMBO J.
, vol.14
, pp. 5579-5588
-
-
Kischkel, F.C.1
Hellbardt, S.2
Behrmann, I.3
Germer, M.4
Pawlita, M.5
Krammer, P.H.6
Peter, M.E.7
-
79
-
-
33745248467
-
ATM activation by a sulfhydryl-reactive inflammatory cyclopentenone prostaglandin
-
Kobayashi M., Ono H., Mihara K., Tauchi H., Komatsu K., Shibata T., Shimizu H., Uchida K., Yamamoto K. ATM activation by a sulfhydryl-reactive inflammatory cyclopentenone prostaglandin. Genes Cells 2006, 11:779-789.
-
(2006)
Genes Cells
, vol.11
, pp. 779-789
-
-
Kobayashi, M.1
Ono, H.2
Mihara, K.3
Tauchi, H.4
Komatsu, K.5
Shibata, T.6
Shimizu, H.7
Uchida, K.8
Yamamoto, K.9
-
80
-
-
0012954726
-
15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis
-
Kondo M., Shibata T., Kumagai T., Osawa T., Shibata N., Kobayashi M., Sasaki S., Iwata M., Noguchi N., Uchida K. 15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:7367-7372.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 7367-7372
-
-
Kondo, M.1
Shibata, T.2
Kumagai, T.3
Osawa, T.4
Shibata, N.5
Kobayashi, M.6
Sasaki, S.7
Iwata, M.8
Noguchi, N.9
Uchida, K.10
-
81
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
Kroemer G., Galluzzi L., Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 2007, 87:99-163.
-
(2007)
Physiol. Rev.
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
82
-
-
4644337725
-
Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer
-
Krysan K., Dalwadi H., Sharma S., Pold M., Dubinett S. Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer. Cancer Res. 2004, 64:6359-6362.
-
(2004)
Cancer Res.
, vol.64
, pp. 6359-6362
-
-
Krysan, K.1
Dalwadi, H.2
Sharma, S.3
Pold, M.4
Dubinett, S.5
-
83
-
-
79951682124
-
Prostaglandins antagonistically control Bax activation during apoptosis
-
Lalier L., Cartron P.F., Olivier C., Loge C., Bougras G., Robert J.M., Oliver L., Vallette F.M. Prostaglandins antagonistically control Bax activation during apoptosis. Cell Death Differ. 2011, 18:528-537.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 528-537
-
-
Lalier, L.1
Cartron, P.F.2
Olivier, C.3
Loge, C.4
Bougras, G.5
Robert, J.M.6
Oliver, L.7
Vallette, F.M.8
-
84
-
-
79955157821
-
Increase in intracellular PGE2 induces apoptosis in Bax-expressing colon cancer cell
-
Lalier L., Pedelaborde F., Braud C., Menanteau J., Vallette F.M., Olivier C. Increase in intracellular PGE2 induces apoptosis in Bax-expressing colon cancer cell. BMC Cancer 2011, 11:153.
-
(2011)
BMC Cancer
, vol.11
, pp. 153
-
-
Lalier, L.1
Pedelaborde, F.2
Braud, C.3
Menanteau, J.4
Vallette, F.M.5
Olivier, C.6
-
85
-
-
0034094780
-
Leukotriene C4 synthase. A pivotal enzyme in the biosynthesis of the cysteinyl leukotrienes
-
Lam B.K., Frank Austen K. Leukotriene C4 synthase. A pivotal enzyme in the biosynthesis of the cysteinyl leukotrienes. Am. J. Respir. Crit. Care Med. 2000, 161:S16-S19.
-
(2000)
Am. J. Respir. Crit. Care Med.
, vol.161
-
-
Lam, B.K.1
Frank Austen, K.2
-
86
-
-
32944457661
-
Induction of the permeability transition and cytochrome c release by 15-deoxy-delta-12,14-prostaglandin J2 in mitochondria
-
Landar A., Shiva S., Levonen A.-L., Oh J.-Y., Zaragoza C., Johnson M.S., Darley-usmar V.M. Induction of the permeability transition and cytochrome c release by 15-deoxy-delta-12,14-prostaglandin J2 in mitochondria. Biochem. J. 2006, 394:185-195.
-
(2006)
Biochem. J.
, vol.394
, pp. 185-195
-
-
Landar, A.1
Shiva, S.2
Levonen, A.-L.3
Oh, J.-Y.4
Zaragoza, C.5
Johnson, M.S.6
Darley-usmar, V.M.7
-
87
-
-
33644858084
-
The role of receptor internalization in CD95 signaling
-
Lee K.H., Feig C., Tchikov V., Schickel R., Hallas C., Schutze S., Peter M.E., Chan A.C. The role of receptor internalization in CD95 signaling. EMBO J. 2006, 25:1009-1023.
-
(2006)
EMBO J.
, vol.25
, pp. 1009-1023
-
-
Lee, K.H.1
Feig, C.2
Tchikov, V.3
Schickel, R.4
Hallas, C.5
Schutze, S.6
Peter, M.E.7
Chan, A.C.8
-
88
-
-
43849099390
-
15-Deoxy-δ12,14-prostaglandin J2 induces apoptosis via JNK-mediated mitochondrial pathway in osteoblastic cells
-
Lee S.J., Kim M.S., Park J.Y., Woo J.S., Kim Y.K. 15-Deoxy-δ12,14-prostaglandin J2 induces apoptosis via JNK-mediated mitochondrial pathway in osteoblastic cells. Toxicology 2008, 248:121-129.
-
(2008)
Toxicology
, vol.248
, pp. 121-129
-
-
Lee, S.J.1
Kim, M.S.2
Park, J.Y.3
Woo, J.S.4
Kim, Y.K.5
-
89
-
-
74849085722
-
Prostaglandin A2 activates intrinsic apoptotic pathway by direct interaction with mitochondria in HL-60 cells
-
Lee S.-Y., Ahn J.-H., Ko K.W., Kim J., Jeong S.W., Kim I.-K., Kim J., Kim H.-S. Prostaglandin A2 activates intrinsic apoptotic pathway by direct interaction with mitochondria in HL-60 cells. Prostaglandins Other Lipid Mediat. 2010, 91:30-37.
-
(2010)
Prostaglandins Other Lipid Mediat.
, vol.91
, pp. 30-37
-
-
Lee, S.-Y.1
Ahn, J.-H.2
Ko, K.W.3
Kim, J.4
Jeong, S.W.5
Kim, I.-K.6
Kim, J.7
Kim, H.-S.8
-
90
-
-
83855160815
-
15-Lipoxygenase-1 as a tumor suppressor gene in colon cancer: is the verdict in?
-
Lee S.I., Zuo X., Shureiqi I. 15-Lipoxygenase-1 as a tumor suppressor gene in colon cancer: is the verdict in?. Cancer Metastasis Rev. 2011, 30:481-491.
-
(2011)
Cancer Metastasis Rev.
, vol.30
, pp. 481-491
-
-
Lee, S.I.1
Zuo, X.2
Shureiqi, I.3
-
91
-
-
0035851123
-
15-Deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors
-
Li L., Tao J., Davaille J., Feral C., Mallat A., Rieusset J., Vidal H., Lotersztajn S. 15-Deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors. J. Biol. Chem. 2001, 276:38152-38158.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38152-38158
-
-
Li, L.1
Tao, J.2
Davaille, J.3
Feral, C.4
Mallat, A.5
Rieusset, J.6
Vidal, H.7
Lotersztajn, S.8
-
92
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin Y., Devin A., Rodriguez Y., Liu Z.G. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev. 1999, 13:2514-2526.
-
(1999)
Genes Dev.
, vol.13
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.G.4
-
93
-
-
23044508580
-
Combination of cyclooxygenase-2 inhibitors and oxaliplatin increases the growth inhibition and death in human colon cancer cells
-
Lin J., Hsiao P.W., Chiu T.H., Chao J.I. Combination of cyclooxygenase-2 inhibitors and oxaliplatin increases the growth inhibition and death in human colon cancer cells. Biochem. Pharmacol. 2005, 70:658-667.
-
(2005)
Biochem. Pharmacol.
, vol.70
, pp. 658-667
-
-
Lin, J.1
Hsiao, P.W.2
Chiu, T.H.3
Chao, J.I.4
-
94
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
-
Liu X., Kim C.N., Yang J., Jemmerson R., Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 1996, 86:147-157.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
95
-
-
80054781373
-
Epoxyeicosatrienoic acids attenuate reactive oxygen species level, mitochondrial dysfunction, caspase activation, and apoptosis in carcinoma cells treated with arsenic trioxide
-
Liu L., Chen C., Gong W., Li Y., Edin M.L., Zeldin D.C., Wang D.W. Epoxyeicosatrienoic acids attenuate reactive oxygen species level, mitochondrial dysfunction, caspase activation, and apoptosis in carcinoma cells treated with arsenic trioxide. J. Pharmacol. Exp. Ther. 2011, 339:451-463.
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.339
, pp. 451-463
-
-
Liu, L.1
Chen, C.2
Gong, W.3
Li, Y.4
Edin, M.L.5
Zeldin, D.C.6
Wang, D.W.7
-
96
-
-
79960837542
-
Eicosanoids, [beta]-cell function, and diabetes
-
Luo P., Wang M.-H. Eicosanoids, [beta]-cell function, and diabetes. Prostaglandins Other Lipid Mediat. 2011, 95:1-10.
-
(2011)
Prostaglandins Other Lipid Mediat.
, vol.95
, pp. 1-10
-
-
Luo, P.1
Wang, M.-H.2
-
97
-
-
34249980917
-
Effect of 15-lipoxygenase metabolites, 15-(S)-HPETE and 15-(S)-HETE on chronic myelogenous leukemia cell line K-562: reactive oxygen species (ROS) mediate caspase-dependent apoptosis
-
Mahipal S.V.K., Subhashini J., Reddy M.C., Reddy M.M., Anilkumar K., Roy K.R., Reddy G.V., Reddanna P. Effect of 15-lipoxygenase metabolites, 15-(S)-HPETE and 15-(S)-HETE on chronic myelogenous leukemia cell line K-562: reactive oxygen species (ROS) mediate caspase-dependent apoptosis. Biochem. Pharmacol. 2007, 74:202-214.
-
(2007)
Biochem. Pharmacol.
, vol.74
, pp. 202-214
-
-
Mahipal, S.V.K.1
Subhashini, J.2
Reddy, M.C.3
Reddy, M.M.4
Anilkumar, K.5
Roy, K.R.6
Reddy, G.V.7
Reddanna, P.8
-
98
-
-
77956396930
-
White tea extract induces apoptosis in non-small cell lung cancer cells: the role of peroxisome proliferator-activated receptor-γ and 15-lipoxygenases
-
Mao J.T., Nie W.-X., Tsu I.-H., Jin Y.-S., Rao J.Y., Lu Q.-Y., Zhang Z.-F., Go V.L.W., Serio K.J. White tea extract induces apoptosis in non-small cell lung cancer cells: the role of peroxisome proliferator-activated receptor-γ and 15-lipoxygenases. Cancer Prev. Res. 2010, 3:1132-1140.
-
(2010)
Cancer Prev. Res.
, vol.3
, pp. 1132-1140
-
-
Mao, J.T.1
Nie, W.-X.2
Tsu, I.-H.3
Jin, Y.-S.4
Rao, J.Y.5
Lu, Q.-Y.6
Zhang, Z.-F.7
Go, V.L.W.8
Serio, K.J.9
-
99
-
-
29244467982
-
Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae
-
Martin S., Phillips D.C., Szekely-Szucs K., Elghazi L., Desmots F., Houghton J.A. Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae. Cancer Res. 2005, 65:11447-11458.
-
(2005)
Cancer Res.
, vol.65
, pp. 11447-11458
-
-
Martin, S.1
Phillips, D.C.2
Szekely-Szucs, K.3
Elghazi, L.4
Desmots, F.5
Houghton, J.A.6
-
100
-
-
21744455741
-
The mitochondrial respiratory complex I is a target for 15-deoxy-{Delta}12,14-prostaglandin J2 action
-
Martinez B., Perez-Castillo A., Santos A. The mitochondrial respiratory complex I is a target for 15-deoxy-{Delta}12,14-prostaglandin J2 action. J. Lipid Res. 2005, 46:736-743.
-
(2005)
J. Lipid Res.
, vol.46
, pp. 736-743
-
-
Martinez, B.1
Perez-Castillo, A.2
Santos, A.3
-
101
-
-
34548018348
-
Overexpression of cysteinyl LT1 receptor in prostate cancer and CysLT1R antagonist inhibits prostate cancer cell growth through apoptosis
-
Matsuyama M., Hayama T., Funao K., Kawahito Y., Sano H., Takemoto Y., Nakatani T., Yoshimura R. Overexpression of cysteinyl LT1 receptor in prostate cancer and CysLT1R antagonist inhibits prostate cancer cell growth through apoptosis. Oncol. Rep. 2007, 18:99-104.
-
(2007)
Oncol. Rep.
, vol.18
, pp. 99-104
-
-
Matsuyama, M.1
Hayama, T.2
Funao, K.3
Kawahito, Y.4
Sano, H.5
Takemoto, Y.6
Nakatani, T.7
Yoshimura, R.8
-
102
-
-
33646554857
-
The inflammatory mediator leukotriene D4 induces beta-catenin signaling and its association with antiapoptotic Bcl-2 in intestinal epithelial cells
-
Mezhybovska M., Wikstrom K., Ohd J.F., Sjolander A. The inflammatory mediator leukotriene D4 induces beta-catenin signaling and its association with antiapoptotic Bcl-2 in intestinal epithelial cells. J. Biol. Chem. 2006, 281:6776-6784.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 6776-6784
-
-
Mezhybovska, M.1
Wikstrom, K.2
Ohd, J.F.3
Sjolander, A.4
-
103
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O., Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003, 114:181-190.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
104
-
-
80054080478
-
Isoprostane generation and function
-
Milne G.L., Yin H., Hardy K.D., Davies S.S., Roberts L.J. Isoprostane generation and function. Chem. Rev. 2011, 111:5973-5996.
-
(2011)
Chem. Rev.
, vol.111
, pp. 5973-5996
-
-
Milne, G.L.1
Yin, H.2
Hardy, K.D.3
Davies, S.S.4
Roberts, L.J.5
-
105
-
-
79955947190
-
Cyp3a4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET)
-
Mitra R., Guo Z., Milani M., Mesaros C., Rodriguez M., Nguyen J., Luo X., Clarke D., Lamba J., Schuetz E., Donner D.B., Puli N., Falck J.R., Capdevila J., Gupta K., Blair I.A., Potter D.A. cyp3a4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET). J. Biol. Chem. 2011, 286:17543-17559.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 17543-17559
-
-
Mitra, R.1
Guo, Z.2
Milani, M.3
Mesaros, C.4
Rodriguez, M.5
Nguyen, J.6
Luo, X.7
Clarke, D.8
Lamba, J.9
Schuetz, E.10
Donner, D.B.11
Puli, N.12
Falck, J.R.13
Capdevila, J.14
Gupta, K.15
Blair, I.A.16
Potter, D.A.17
-
106
-
-
0037216649
-
15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils
-
Monneret G., Cossette C., Gravel S., Rokach J., Powell W.S. 15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils. J. Pharmacol. Exp. Ther. 2003, 304:349-355.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.304
, pp. 349-355
-
-
Monneret, G.1
Cossette, C.2
Gravel, S.3
Rokach, J.4
Powell, W.S.5
-
107
-
-
84860372567
-
Activation of mitochondrial calcium-independent phospholipase A2γ (iPLA2γ) by divalent cations mediating arachidonate release and production of downstream eicosanoids
-
Moon S.H., Jenkins C.M., Liu X., Guan S., Mancuso D.J., Gross R.W. Activation of mitochondrial calcium-independent phospholipase A2γ (iPLA2γ) by divalent cations mediating arachidonate release and production of downstream eicosanoids. J. Biol. Chem. 2012, 287:14880-14895.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 14880-14895
-
-
Moon, S.H.1
Jenkins, C.M.2
Liu, X.3
Guan, S.4
Mancuso, D.J.5
Gross, R.W.6
-
108
-
-
0034255499
-
Inactivation of wild-type p53 tumor suppressor by electrophilic prostaglandins
-
Moos P.J., Edes K., Fitzpatrick F.A. Inactivation of wild-type p53 tumor suppressor by electrophilic prostaglandins. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:9215-9220.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 9215-9220
-
-
Moos, P.J.1
Edes, K.2
Fitzpatrick, F.A.3
-
109
-
-
0037428454
-
Electrophilic prostaglandins and lipid aldehydes repress redox-sensitive transcription factors p53 and hypoxia-inducible factor by impairing the selenoprotein thioredoxin reductase
-
Moos P.J., Edes K., Cassidy P., Massuda E., Fitzpatrick F.A. Electrophilic prostaglandins and lipid aldehydes repress redox-sensitive transcription factors p53 and hypoxia-inducible factor by impairing the selenoprotein thioredoxin reductase. J. Biol. Chem. 2003, 278:745-750.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 745-750
-
-
Moos, P.J.1
Edes, K.2
Cassidy, P.3
Massuda, E.4
Fitzpatrick, F.A.5
-
110
-
-
0038304520
-
Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins
-
Moreau C., Cartron P.F., Hunt A., Meflah K., Green D.R., Evan G., Vallette F.M., Juin P. Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins. J. Biol. Chem. 2003, 278:19426-19435.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19426-19435
-
-
Moreau, C.1
Cartron, P.F.2
Hunt, A.3
Meflah, K.4
Green, D.R.5
Evan, G.6
Vallette, F.M.7
Juin, P.8
-
111
-
-
4544351939
-
Activation of the orphan nuclear receptor RORalpha counteracts the proliferative effect of fatty acids on prostate cancer cells: crucial role of 5-lipoxygenase
-
Moretti R.M., Montagnani Marelli M., Sala A., Motta M., Limonta P. Activation of the orphan nuclear receptor RORalpha counteracts the proliferative effect of fatty acids on prostate cancer cells: crucial role of 5-lipoxygenase. Int. J. Cancer 2004, 112:87-93.
-
(2004)
Int. J. Cancer
, vol.112
, pp. 87-93
-
-
Moretti, R.M.1
Montagnani Marelli, M.2
Sala, A.3
Motta, M.4
Limonta, P.5
-
112
-
-
0025572704
-
2-like compounds are produced in vivo in humans by a noncyclooxygenase, free radical-catalyzed mechanism
-
2-like compounds are produced in vivo in humans by a noncyclooxygenase, free radical-catalyzed mechanism. Proc. Natl. Acad. Sci. U. S. A. 1990, 87:9383-9387.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 9383-9387
-
-
Morrow, J.D.1
Hill, E.2
Burk, R.F.3
Nammour, T.M.4
Badr, K.F.5
Roberts, L.J.6
-
113
-
-
37849014269
-
Inhibition of thromboxane synthase activity modulates bladder cancer cell responses to chemotherapeutic agents
-
Moussa O., Riker J.M., Klein J., Fraig M., Halushka P.V., Watson D.K. Inhibition of thromboxane synthase activity modulates bladder cancer cell responses to chemotherapeutic agents. Oncogene 2008, 27:55-62.
-
(2008)
Oncogene
, vol.27
, pp. 55-62
-
-
Moussa, O.1
Riker, J.M.2
Klein, J.3
Fraig, M.4
Halushka, P.V.5
Watson, D.K.6
-
114
-
-
0036070772
-
Pharmacophore model for novel inhibitors of ubiquitin isopeptidases that induce p53-independent cell death
-
Mullally J.E., Fitzpatrick F.A. Pharmacophore model for novel inhibitors of ubiquitin isopeptidases that induce p53-independent cell death. Mol. Pharmacol. 2002, 62:351-358.
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 351-358
-
-
Mullally, J.E.1
Fitzpatrick, F.A.2
-
115
-
-
0038606743
-
Role of leukotrienes in the regulation of human granulocyte behaviour: dissociation between agonist-induced activation and retardation of apoptosis
-
Murray J., Ward C., O'Flaherty J.T., Dransfield I., Haslett C., Chilvers E.R., Rossi A.G. Role of leukotrienes in the regulation of human granulocyte behaviour: dissociation between agonist-induced activation and retardation of apoptosis. Br. J. Pharmacol. 2003, 139:388-398.
-
(2003)
Br. J. Pharmacol.
, vol.139
, pp. 388-398
-
-
Murray, J.1
Ward, C.2
O'Flaherty, J.T.3
Dransfield, I.4
Haslett, C.5
Chilvers, E.R.6
Rossi, A.G.7
-
116
-
-
17444386729
-
Cyclopentenone eicosanoids as mediators of neurodegeneration: a pathogenic mechanism of oxidative stress-mediated and cyclooxygenase-mediated neurotoxicity
-
Musiek E.S., Milne G.L., McLaughlin B., Morrow J.D. Cyclopentenone eicosanoids as mediators of neurodegeneration: a pathogenic mechanism of oxidative stress-mediated and cyclooxygenase-mediated neurotoxicity. Brain Pathol. 2005, 15:149-158.
-
(2005)
Brain Pathol.
, vol.15
, pp. 149-158
-
-
Musiek, E.S.1
Milne, G.L.2
McLaughlin, B.3
Morrow, J.D.4
-
117
-
-
33646549564
-
Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration
-
Musiek E.S., Breeding R.S., Milne G.L., Zanoni G., Morrow J.D., McLaughlin B. Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration. J. Neurochem. 2006, 97:1301-1313.
-
(2006)
J. Neurochem.
, vol.97
, pp. 1301-1313
-
-
Musiek, E.S.1
Breeding, R.S.2
Milne, G.L.3
Zanoni, G.4
Morrow, J.D.5
McLaughlin, B.6
-
118
-
-
35348913718
-
Electrophilic cyclopentenone isoprostanes in neurodegeneration
-
Musiek E.S., McLaughlin B., Morrow J.D. Electrophilic cyclopentenone isoprostanes in neurodegeneration. J. Mol. Neurosci. 2007, 33:80-86.
-
(2007)
J. Mol. Neurosci.
, vol.33
, pp. 80-86
-
-
Musiek, E.S.1
McLaughlin, B.2
Morrow, J.D.3
-
119
-
-
50649103946
-
Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the {omega}-3 polyunsaturated fatty acid docosahexaenoic acid
-
Musiek E.S., Brooks J.D., Joo M., Brunoldi E., Porta A., Zanoni G., Vidari G., Blackwell T.S., Montine T.J., Milne G.L., McLaughlin B., Morrow J.D. Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the {omega}-3 polyunsaturated fatty acid docosahexaenoic acid. J. Biol. Chem. 2008, 283:19927-19935.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 19927-19935
-
-
Musiek, E.S.1
Brooks, J.D.2
Joo, M.3
Brunoldi, E.4
Porta, A.5
Zanoni, G.6
Vidari, G.7
Blackwell, T.S.8
Montine, T.J.9
Milne, G.L.10
McLaughlin, B.11
Morrow, J.D.12
-
120
-
-
33748323449
-
15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis
-
Nakata S., Yoshida T., Shiraishi T., Horinaka M., Kouhara J., Wakada M., Sakai T. 15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis. Mol. Cancer Ther. 2006, 5:1827-1835.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 1827-1835
-
-
Nakata, S.1
Yoshida, T.2
Shiraishi, T.3
Horinaka, M.4
Kouhara, J.5
Wakada, M.6
Sakai, T.7
-
121
-
-
34047196056
-
Prostacyclin prevents pulmonary endothelial cell apoptosis induced by cigarette smoke
-
Nana-Sinkam S.P., Lee J.D., Sotto-Santiago S., Stearman R.S., Keith R.L., Choudhury Q., Cool C., Parr J., Moore M.D., Bull T.M., Voelkel N.F., Geraci M.W. Prostacyclin prevents pulmonary endothelial cell apoptosis induced by cigarette smoke. Am. J. Respir. Cri.t Care Med. 2007, 175:676-685.
-
(2007)
Am. J. Respir. Cri.t Care Med.
, vol.175
, pp. 676-685
-
-
Nana-Sinkam, S.P.1
Lee, J.D.2
Sotto-Santiago, S.3
Stearman, R.S.4
Keith, R.L.5
Choudhury, Q.6
Cool, C.7
Parr, J.8
Moore, M.D.9
Bull, T.M.10
Voelkel, N.F.11
Geraci, M.W.12
-
122
-
-
0037459081
-
Mitochondria: releasing power for life and unleashing the machineries of death
-
Newmeyer D.D., Ferguson-Miller S. Mitochondria: releasing power for life and unleashing the machineries of death. Cell 2003, 112:481-490.
-
(2003)
Cell
, vol.112
, pp. 481-490
-
-
Newmeyer, D.D.1
Ferguson-Miller, S.2
-
123
-
-
4344713683
-
Control of life cycle of mouse adipogenic 3T3-L1 cells by dietary lipids and metabolic factors
-
Nishimura K., Hatano Y., Setoyama T., Tsumagari H., Miyashita K., Lu S., Jisaka M., Nagaya T., Yokota K. Control of life cycle of mouse adipogenic 3T3-L1 cells by dietary lipids and metabolic factors. Appl. Biochem. Biotechnol. 2004, 118:97-114.
-
(2004)
Appl. Biochem. Biotechnol.
, vol.118
, pp. 97-114
-
-
Nishimura, K.1
Hatano, Y.2
Setoyama, T.3
Tsumagari, H.4
Miyashita, K.5
Lu, S.6
Jisaka, M.7
Nagaya, T.8
Yokota, K.9
-
124
-
-
33748994802
-
Endogenous prostaglandins E2 and F 2alpha serve as an anti-apoptotic factor against apoptosis induced by tumor necrosis factor-alpha in mouse 3T3-L1 preadipocytes
-
Nishimura K., Setoyama T., Tsumagari H., Miyata N., Hatano Y., Xu L., Jisaka M., Nagaya T., Yokota K. Endogenous prostaglandins E2 and F 2alpha serve as an anti-apoptotic factor against apoptosis induced by tumor necrosis factor-alpha in mouse 3T3-L1 preadipocytes. Biosci. Biotechnol. Biochem. 2006, 70:2145-2153.
-
(2006)
Biosci. Biotechnol. Biochem.
, vol.70
, pp. 2145-2153
-
-
Nishimura, K.1
Setoyama, T.2
Tsumagari, H.3
Miyata, N.4
Hatano, Y.5
Xu, L.6
Jisaka, M.7
Nagaya, T.8
Yokota, K.9
-
125
-
-
0025105498
-
Immunohistochemical localization of thromboxane synthase in human tissues
-
Nusing R., Lesch R., Ullrich V. Immunohistochemical localization of thromboxane synthase in human tissues. Eicosanoids 1990, 3:53-58.
-
(1990)
Eicosanoids
, vol.3
, pp. 53-58
-
-
Nusing, R.1
Lesch, R.2
Ullrich, V.3
-
126
-
-
0033778357
-
Leukotrienes induce cell-survival signaling in intestinal epithelial cells
-
Ohd J.F., Wikstrom K., Sjolander A. Leukotrienes induce cell-survival signaling in intestinal epithelial cells. Gastroenterology 2000, 119:1007-1018.
-
(2000)
Gastroenterology
, vol.119
, pp. 1007-1018
-
-
Ohd, J.F.1
Wikstrom, K.2
Sjolander, A.3
-
127
-
-
0037207863
-
Expression of the leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas
-
Ohd J.F., Nielsen C.K., Campbell J., Landberg G., Lofberg H., Sjolander A. Expression of the leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas. Gastroenterology 2003, 124:57-70.
-
(2003)
Gastroenterology
, vol.124
, pp. 57-70
-
-
Ohd, J.F.1
Nielsen, C.K.2
Campbell, J.3
Landberg, G.4
Lofberg, H.5
Sjolander, A.6
-
128
-
-
0037207863
-
Expression of the leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas
-
Öhd J.F., Nielsen C.K., Campbell J., Landberg G., Löfberg H., Sjölander A. Expression of the leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas. Gastroenterology 2003, 124:57-70.
-
(2003)
Gastroenterology
, vol.124
, pp. 57-70
-
-
Öhd, J.F.1
Nielsen, C.K.2
Campbell, J.3
Landberg, G.4
Löfberg, H.5
Sjölander, A.6
-
129
-
-
51449083129
-
Cyclooxygenase-2-derived endogenous prostacyclin reduces apoptosis and enhances embryo viability in mouse
-
Pakrasi P.L., Jain A.K. Cyclooxygenase-2-derived endogenous prostacyclin reduces apoptosis and enhances embryo viability in mouse. Prostaglandins Leukot. Essent. Fatty Acids 2008, 79:27-33.
-
(2008)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.79
, pp. 27-33
-
-
Pakrasi, P.L.1
Jain, A.K.2
-
130
-
-
80455155111
-
Cyclooxygenase-2-derived prostacyclin protective role on endotoxin-induced mouse cardiomyocyte mortality
-
Panaro M.A., Pricci M., Meziani F., Ragot T., Andriantsitohaina R., Mitolo V., Tesse A. Cyclooxygenase-2-derived prostacyclin protective role on endotoxin-induced mouse cardiomyocyte mortality. Cardiovasc. Toxicol. 2011, 11:347-356.
-
(2011)
Cardiovasc. Toxicol.
, vol.11
, pp. 347-356
-
-
Panaro, M.A.1
Pricci, M.2
Meziani, F.3
Ragot, T.4
Andriantsitohaina, R.5
Mitolo, V.6
Tesse, A.7
-
131
-
-
84855453198
-
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice
-
Panigrahy D., Edin M.L., Lee C.R., Huang S., Bielenberg D.R., Butterfield C.E., Barnés C.M., Mammoto A., Mammoto T., Luria A., Benny O., Chaponis D.M., Dudley A.C., Greene E.R., Vergilio J.-A., Pietramaggiori G., Scherer-Pietramaggiori S.S., Short S.M., Seth M., Lih F.B., Tomer K.B., Yang J., Schwendener R.A., Hammock B.D., Falck J.R., Manthati V.L., Ingber D.E., Kaipainen A., D'Amore P.A., Kieran M.W., Zeldin D.C. Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J. Clin. Invest. 2012, 122:178-191.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 178-191
-
-
Panigrahy, D.1
Edin, M.L.2
Lee, C.R.3
Huang, S.4
Bielenberg, D.R.5
Butterfield, C.E.6
Barnés, C.M.7
Mammoto, A.8
Mammoto, T.9
Luria, A.10
Benny, O.11
Chaponis, D.M.12
Dudley, A.C.13
Greene, E.R.14
Vergilio, J.-A.15
Pietramaggiori, G.16
Scherer-Pietramaggiori, S.S.17
Short, S.M.18
Seth, M.19
Lih, F.B.20
Tomer, K.B.21
Yang, J.22
Schwendener, R.A.23
Hammock, B.D.24
Falck, J.R.25
Manthati, V.L.26
Ingber, D.E.27
Kaipainen, A.28
D'Amore, P.A.29
Kieran, M.W.30
Zeldin, D.C.31
more..
-
132
-
-
0242582865
-
Hydrogen peroxide signaling through tumor necrosis factor receptor 1 leads to selective activation of c-Jun N-terminal kinase
-
Pantano C., Shrivastava P., McElhinney B., Janssen-Heininger Y. Hydrogen peroxide signaling through tumor necrosis factor receptor 1 leads to selective activation of c-Jun N-terminal kinase. J. Biol. Chem. 2003, 278:44091-44096.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44091-44096
-
-
Pantano, C.1
Shrivastava, P.2
McElhinney, B.3
Janssen-Heininger, Y.4
-
133
-
-
36249002916
-
PKB and the mitochondria: AKTing on apoptosis
-
Parcellier A., Tintignac L.A., Zhuravleva E., Hemmings B.A. PKB and the mitochondria: AKTing on apoptosis. Cell. Signal. 2008, 20:21-30.
-
(2008)
Cell. Signal.
, vol.20
, pp. 21-30
-
-
Parcellier, A.1
Tintignac, L.A.2
Zhuravleva, E.3
Hemmings, B.A.4
-
134
-
-
0033551134
-
Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2
-
Petrova T.V., Akama K.T., Van Eldik L.J. Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:4668-4673.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 4668-4673
-
-
Petrova, T.V.1
Akama, K.T.2
Van Eldik, L.J.3
-
136
-
-
0030302508
-
Prostaglandin E2 induces apoptosis in resting immature and mature human lymphocytes: a c-Myc-dependent and Bcl-2-independent associated pathway
-
Pica F., Franzese O., D'Onofrio C., Bonmassar E., Favalli C., Garaci E. Prostaglandin E2 induces apoptosis in resting immature and mature human lymphocytes: a c-Myc-dependent and Bcl-2-independent associated pathway. J. Pharmacol. Exp. Ther. 1996, 277:1793-1800.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.277
, pp. 1793-1800
-
-
Pica, F.1
Franzese, O.2
D'Onofrio, C.3
Bonmassar, E.4
Favalli, C.5
Garaci, E.6
-
137
-
-
0036570319
-
Mechanisms controlling cell cycle arrest and induction of apoptosis after 12-lipoxygenase inhibition in prostate cancer cells
-
Pidgeon G.P., Kandouz M., Meram A., Honn K.V. Mechanisms controlling cell cycle arrest and induction of apoptosis after 12-lipoxygenase inhibition in prostate cancer cells. Cancer Res. 2002, 62:2721-2727.
-
(2002)
Cancer Res.
, vol.62
, pp. 2721-2727
-
-
Pidgeon, G.P.1
Kandouz, M.2
Meram, A.3
Honn, K.V.4
-
138
-
-
36149000163
-
Lipoxygenase metabolism: roles in tumor progression and survival
-
Pidgeon G.P., Lysaght J., Krishnamoorthy S., Reynolds J.V., O'Byrne K., Nie D., Honn K.V. Lipoxygenase metabolism: roles in tumor progression and survival. Cancer Metastasis Rev. 2007, 26:503-524.
-
(2007)
Cancer Metastasis Rev.
, vol.26
, pp. 503-524
-
-
Pidgeon, G.P.1
Lysaght, J.2
Krishnamoorthy, S.3
Reynolds, J.V.4
O'Byrne, K.5
Nie, D.6
Honn, K.V.7
-
139
-
-
0035199286
-
The peroxisome proliferator-activated receptor gamma is an inhibitor of ErbBs activity in human breast cancer cells
-
Pignatelli M., Cortes-Canteli M., Lai C., Santos A., Perez-Castillo A. The peroxisome proliferator-activated receptor gamma is an inhibitor of ErbBs activity in human breast cancer cells. J. Cell Sci. 2001, 114:4117-4126.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 4117-4126
-
-
Pignatelli, M.1
Cortes-Canteli, M.2
Lai, C.3
Santos, A.4
Perez-Castillo, A.5
-
140
-
-
13444292545
-
15-Deoxy-δ-12,14-prostaglandin J2 induces programmed cell death of breast cancer cells by a pleiotropic mechanism
-
Pignatelli M., Sánchez-Rodríguez J., Santos A., Perez-Castillo A. 15-Deoxy-δ-12,14-prostaglandin J2 induces programmed cell death of breast cancer cells by a pleiotropic mechanism. Carcinogenesis 2005, 26:81-92.
-
(2005)
Carcinogenesis
, vol.26
, pp. 81-92
-
-
Pignatelli, M.1
Sánchez-Rodríguez, J.2
Santos, A.3
Perez-Castillo, A.4
-
141
-
-
13844314302
-
Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis
-
Plataki M., Koutsopoulos A.V., Darivianaki K., Delides G., Siafakas N.M., Bouros D. Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis. Chest 2005, 127:266-274.
-
(2005)
Chest
, vol.127
, pp. 266-274
-
-
Plataki, M.1
Koutsopoulos, A.V.2
Darivianaki, K.3
Delides, G.4
Siafakas, N.M.5
Bouros, D.6
-
142
-
-
0032586845
-
Prostaglandin E2 inhibits T cell activation-induced apoptosis and Fas-mediated cellular cytotoxicity by blockade of Fas-ligand induction
-
Porter B.O., Malek T.R. Prostaglandin E2 inhibits T cell activation-induced apoptosis and Fas-mediated cellular cytotoxicity by blockade of Fas-ligand induction. Eur. J. Immunol. 1999, 29:2360-2365.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 2360-2365
-
-
Porter, B.O.1
Malek, T.R.2
-
143
-
-
0029946187
-
Colocalization of cytosolic phospholipase A2, 5-lipoxygenase, and 5-lipoxygenase-activating protein at the nuclear membrane of A23187-stimulated human neutrophils
-
Pouliot M., McDonald P.P., Krump E., Mancini J.A., McColl S.R., Weech P.K., Borgeat P. Colocalization of cytosolic phospholipase A2, 5-lipoxygenase, and 5-lipoxygenase-activating protein at the nuclear membrane of A23187-stimulated human neutrophils. Eur. J. Biochem. 1996, 238:250-258.
-
(1996)
Eur. J. Biochem.
, vol.238
, pp. 250-258
-
-
Pouliot, M.1
McDonald, P.P.2
Krump, E.3
Mancini, J.A.4
McColl, S.R.5
Weech, P.K.6
Borgeat, P.7
-
144
-
-
21244494463
-
Prostacyclin prevents nitric oxide-induced megakaryocyte apoptosis
-
Pozner R.G., Negrotto S., D'Atri L.P., Kotler M.L., Lazzari M.A., Gomez R.M., Schattner M. Prostacyclin prevents nitric oxide-induced megakaryocyte apoptosis. Br. J. Pharmacol. 2005, 145:283-292.
-
(2005)
Br. J. Pharmacol.
, vol.145
, pp. 283-292
-
-
Pozner, R.G.1
Negrotto, S.2
D'Atri, L.P.3
Kotler, M.L.4
Lazzari, M.A.5
Gomez, R.M.6
Schattner, M.7
-
145
-
-
0037087760
-
Inhibition of inducible prostaglandin E(2) synthase by 15-deoxy-Delta(12,14)-prostaglandin J(2) and polyunsaturated fatty acids
-
Quraishi O., Mancini J.A., Riendeau D. Inhibition of inducible prostaglandin E(2) synthase by 15-deoxy-Delta(12,14)-prostaglandin J(2) and polyunsaturated fatty acids. Biochem. Pharmacol. 2002, 63:1183-1189.
-
(2002)
Biochem. Pharmacol.
, vol.63
, pp. 1183-1189
-
-
Quraishi, O.1
Mancini, J.A.2
Riendeau, D.3
-
148
-
-
0021770929
-
Leukotriene A4 hydrolase in human leukocytes. Purification and properties
-
Radmark O., Shimizu T., Jornvall H., Samuelsson B. Leukotriene A4 hydrolase in human leukocytes. Purification and properties. J. Biol. Chem. 1984, 259:12339-12345.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 12339-12345
-
-
Radmark, O.1
Shimizu, T.2
Jornvall, H.3
Samuelsson, B.4
-
149
-
-
0242321274
-
EP2 and EP4 prostanoid receptor signaling
-
Regan J.W. EP2 and EP4 prostanoid receptor signaling. Life Sci. 2003, 74:143-153.
-
(2003)
Life Sci.
, vol.74
, pp. 143-153
-
-
Regan, J.W.1
-
150
-
-
0028172992
-
Thromboxane A2 receptor blocking abrogates donor-specific unresponsiveness to renal allografts induced by thymic recognition of major histocompatibility allopeptides
-
Remuzzi G., Noris M., Benigni A., Imberti O., Sayegh M.H., Perico N. Thromboxane A2 receptor blocking abrogates donor-specific unresponsiveness to renal allografts induced by thymic recognition of major histocompatibility allopeptides. J. Exp. Med. 1994, 180:1967-1972.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1967-1972
-
-
Remuzzi, G.1
Noris, M.2
Benigni, A.3
Imberti, O.4
Sayegh, M.H.5
Perico, N.6
-
151
-
-
30544448694
-
Role of thromboxane A2 in the induction of apoptosis of immature thymocytes by lipopolysaccharide
-
Rocha P.N., Plumb T.J., Robinson L.A., Spurney R., Pisetsky D., Koller B.H., Coffman T.M. Role of thromboxane A2 in the induction of apoptosis of immature thymocytes by lipopolysaccharide. Clin. Diagn. Lab. Immunol. 2005, 12:896-903.
-
(2005)
Clin. Diagn. Lab. Immunol.
, vol.12
, pp. 896-903
-
-
Rocha, P.N.1
Plumb, T.J.2
Robinson, L.A.3
Spurney, R.4
Pisetsky, D.5
Koller, B.H.6
Coffman, T.M.7
-
152
-
-
0035162355
-
5-Lipoxygenase regulates malignant mesothelial cell survival: involvement of vascular endothelial growth factor
-
Romano M., Catalano A., Nutini M., D'Urbano E., Crescenzi C., Claria J., Libner R., Davi G., Procopio A. 5-Lipoxygenase regulates malignant mesothelial cell survival: involvement of vascular endothelial growth factor. FASEB J. 2001, 15:2326-2336.
-
(2001)
FASEB J.
, vol.15
, pp. 2326-2336
-
-
Romano, M.1
Catalano, A.2
Nutini, M.3
D'Urbano, E.4
Crescenzi, C.5
Claria, J.6
Libner, R.7
Davi, G.8
Procopio, A.9
-
153
-
-
0028819570
-
Cellular regulation of arachidonate mobilization and metabolism
-
Rosenthal M.D., Rzigalinski B.A., Blackmore P.F., Franson R.C. Cellular regulation of arachidonate mobilization and metabolism. Prostaglandins Leukot. Essent. Fatty Acids 1995, 52:93-98.
-
(1995)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.52
, pp. 93-98
-
-
Rosenthal, M.D.1
Rzigalinski, B.A.2
Blackmore, P.F.3
Franson, R.C.4
-
154
-
-
0034610759
-
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of I[kappa]B kinase
-
Rossi A., Kapahi P., Natoli G., Takahashi T., Chen Y., Karin M., Santoro M.G. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of I[kappa]B kinase. Nature 2000, 403:103-118.
-
(2000)
Nature
, vol.403
, pp. 103-118
-
-
Rossi, A.1
Kapahi, P.2
Natoli, G.3
Takahashi, T.4
Chen, Y.5
Karin, M.6
Santoro, M.G.7
-
155
-
-
33845395850
-
Mechanisms of cell death in oxidative stress
-
Ryter S.W., Kim H.P., Hoetzel A., Park J.W., Nakahira K., Wang X., Choi A.M. Mechanisms of cell death in oxidative stress. Antioxid. Redox Signal. 2007, 9:49-89.
-
(2007)
Antioxid. Redox Signal.
, vol.9
, pp. 49-89
-
-
Ryter, S.W.1
Kim, H.P.2
Hoetzel, A.3
Park, J.W.4
Nakahira, K.5
Wang, X.6
Choi, A.M.7
-
156
-
-
13244281555
-
Levuglandins and isolevuglandins: stealthy toxins of oxidative injury
-
Salomon R.G. Levuglandins and isolevuglandins: stealthy toxins of oxidative injury. Antioxid. Redox Signal. 2005, 7:185-201.
-
(2005)
Antioxid. Redox Signal.
, vol.7
, pp. 185-201
-
-
Salomon, R.G.1
-
157
-
-
0022318935
-
Levuglandins: isolation, characterization, and total synthesis of new secoprostanoid products from prostaglandin endoperoxides
-
Salomon R.G., Miller D.B. Levuglandins: isolation, characterization, and total synthesis of new secoprostanoid products from prostaglandin endoperoxides. Adv. Prostaglandin Thromboxane Leukot. Res. 1985, 15:323-326.
-
(1985)
Adv. Prostaglandin Thromboxane Leukot. Res.
, vol.15
, pp. 323-326
-
-
Salomon, R.G.1
Miller, D.B.2
-
158
-
-
0023177955
-
Leukotrienes and lipoxins: structures, biosynthesis, and biological effects
-
Samuelsson B., Dahlen S.E., Lindgren J.A., Rouzer C.A., Serhan C.N. Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science 1987, 237:1171-1176.
-
(1987)
Science
, vol.237
, pp. 1171-1176
-
-
Samuelsson, B.1
Dahlen, S.E.2
Lindgren, J.A.3
Rouzer, C.A.4
Serhan, C.N.5
-
159
-
-
83855165727
-
Cyclooxygenases and lipoxygenases in cancer
-
Schneider C., Pozzi A. Cyclooxygenases and lipoxygenases in cancer. Cancer Metastasis Rev. 2011, 30:277-294.
-
(2011)
Cancer Metastasis Rev.
, vol.30
, pp. 277-294
-
-
Schneider, C.1
Pozzi, A.2
-
160
-
-
31444446617
-
Convergent oxygenation of arachidonic acid by 5-lipoxygenase and cyclooxygenase-2
-
Schneider C., Boeglin W.E., Yin H., Stec D.F., Voehler M. Convergent oxygenation of arachidonic acid by 5-lipoxygenase and cyclooxygenase-2. J. Am. Chem. Soc. 2006, 128:720-721.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 720-721
-
-
Schneider, C.1
Boeglin, W.E.2
Yin, H.3
Stec, D.F.4
Voehler, M.5
-
161
-
-
34249065795
-
Simultaneous inhibition of COX-2 and 5-LOX activities augments growth arrest and death of premalignant and malignant human lung cell lines
-
Schroeder C.P., Yang P., Newman R.A., Lotan R. Simultaneous inhibition of COX-2 and 5-LOX activities augments growth arrest and death of premalignant and malignant human lung cell lines. J. Exp. Ther. Oncol. 2007, 6:183-192.
-
(2007)
J. Exp. Ther. Oncol.
, vol.6
, pp. 183-192
-
-
Schroeder, C.P.1
Yang, P.2
Newman, R.A.3
Lotan, R.4
-
162
-
-
0022895073
-
Lipoxin A. Stereochemistry and biosynthesis
-
Serhan C.N., Nicolaou K.C., Webber S.E., Veale C.A., Dahlen S.E., Puustinen T.J., Samuelsson B. Lipoxin A. Stereochemistry and biosynthesis. J. Biol. Chem. 1986, 261:16340-16345.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 16340-16345
-
-
Serhan, C.N.1
Nicolaou, K.C.2
Webber, S.E.3
Veale, C.A.4
Dahlen, S.E.5
Puustinen, T.J.6
Samuelsson, B.7
-
163
-
-
0032984374
-
15-Lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma
-
Shappell S.B., Boeglin W.E., Olson S.J., Kasper S., Brash A.R. 15-Lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma. Am. J. Pathol. 1999, 155:235-245.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 235-245
-
-
Shappell, S.B.1
Boeglin, W.E.2
Olson, S.J.3
Kasper, S.4
Brash, A.R.5
-
164
-
-
0031984810
-
Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells
-
Sheng H., Shao J., Morrow J.D., Beauchamp R.D., DuBois R.N. Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res. 1998, 58:362-366.
-
(1998)
Cancer Res.
, vol.58
, pp. 362-366
-
-
Sheng, H.1
Shao, J.2
Morrow, J.D.3
Beauchamp, R.D.4
DuBois, R.N.5
-
165
-
-
69949093640
-
15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity
-
Shin S.-W., Seo C.-Y., Han H., Han J.-Y., Jeong J.-S., Kwak J.-Y., Park J.-I. 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity. Clin. Cancer Res. 2009, 15:5414-5425.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 5414-5425
-
-
Shin, S.-W.1
Seo, C.-Y.2
Han, H.3
Han, J.-Y.4
Jeong, J.-S.5
Kwak, J.-Y.6
Park, J.-I.7
-
166
-
-
0042692791
-
The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-δ to induce apoptosis in colorectal cancer cells
-
Shureiqi I., Jiang W., Zuo X., Wu Y., Stimmel J.B., Leesnitzer L.M., Morris J.S., Fan H.-Z., Fischer S.M., Lippman S.M. The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-δ to induce apoptosis in colorectal cancer cells. Proc. Natl. Acad. Sci. 2003, 100:9968-9973.
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 9968-9973
-
-
Shureiqi, I.1
Jiang, W.2
Zuo, X.3
Wu, Y.4
Stimmel, J.B.5
Leesnitzer, L.M.6
Morris, J.S.7
Fan, H.-Z.8
Fischer, S.M.9
Lippman, S.M.10
-
167
-
-
0034739463
-
The expanding superfamily of phospholipase A(2) enzymes: classification and characterization
-
Six D.A., Dennis E.A. The expanding superfamily of phospholipase A(2) enzymes: classification and characterization. Biochim. Biophys. Acta 2000, 1488:1-19.
-
(2000)
Biochim. Biophys. Acta
, vol.1488
, pp. 1-19
-
-
Six, D.A.1
Dennis, E.A.2
-
168
-
-
33645459848
-
Identification of novel protein targets for modification by 15-deoxy-Delta12,14-prostaglandin J2 in mesangial cells reveals multiple interactions with the cytoskeleton
-
Stamatakis K., Sanchez-Gomez F.J., Perez-Sala D. Identification of novel protein targets for modification by 15-deoxy-Delta12,14-prostaglandin J2 in mesangial cells reveals multiple interactions with the cytoskeleton. J. Am. Soc. Nephrol. 2006, 17:89-98.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 89-98
-
-
Stamatakis, K.1
Sanchez-Gomez, F.J.2
Perez-Sala, D.3
-
169
-
-
77954562980
-
Reactive [gamma]-ketoaldehydes formed via the isoprostane pathway disrupt mitochondrial respiration and calcium homeostasis
-
Stavrovskaya I.G., Baranov S.V., Guo X., Davies S.S., Roberts Ii L.J., Kristal B.S. Reactive [gamma]-ketoaldehydes formed via the isoprostane pathway disrupt mitochondrial respiration and calcium homeostasis. Free Radic. Biol. Med. 2010, 49:567-579.
-
(2010)
Free Radic. Biol. Med.
, vol.49
, pp. 567-579
-
-
Stavrovskaya, I.G.1
Baranov, S.V.2
Guo, X.3
Davies, S.S.4
Roberts Ii, L.J.5
Kristal, B.S.6
-
170
-
-
0035053973
-
Cyclopentenone prostaglandins: new insights on biological activities and cellular targets
-
Straus D.S., Glass C.K. Cyclopentenone prostaglandins: new insights on biological activities and cellular targets. Med. Res. Rev. 2001, 21:185-210.
-
(2001)
Med. Res. Rev.
, vol.21
, pp. 185-210
-
-
Straus, D.S.1
Glass, C.K.2
-
171
-
-
33845417905
-
Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation
-
Sugiura H., Liu X., Togo S., Kobayashi T., Shen L., Kawasaki S., Kamio K., Wang X.Q., Mao L.J., Rennard S.I. Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation. J. Cell. Physiol. 2007, 210:99-110.
-
(2007)
J. Cell. Physiol.
, vol.210
, pp. 99-110
-
-
Sugiura, H.1
Liu, X.2
Togo, S.3
Kobayashi, T.4
Shen, L.5
Kawasaki, S.6
Kamio, K.7
Wang, X.Q.8
Mao, L.J.9
Rennard, S.I.10
-
172
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin S.A., Lorenzo H.K., Zamzami N., Marzo I., Snow B.E., Brothers G.M., Mangion J., Jacotot E., Costantini P., Loeffler M., Larochette N., Goodlett D.R., Aebersold R., Siderovski D.P., Penninger J.M., Kroemer G. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999, 397:441-446.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
Mangion, J.7
Jacotot, E.8
Costantini, P.9
Loeffler, M.10
Larochette, N.11
Goodlett, D.R.12
Aebersold, R.13
Siderovski, D.P.14
Penninger, J.M.15
Kroemer, G.16
-
173
-
-
81155133996
-
Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs)
-
Tai H.-H., Chi X., Tong M. Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs). Prostaglandins Other Lipid Mediat. 2011, 96:37-40.
-
(2011)
Prostaglandins Other Lipid Mediat.
, vol.96
, pp. 37-40
-
-
Tai, H.-H.1
Chi, X.2
Tong, M.3
-
174
-
-
0029895338
-
Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis
-
Tang D.G., Chen Y.Q., Honn K.V. Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:5241-5246.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 5241-5246
-
-
Tang, D.G.1
Chen, Y.Q.2
Honn, K.V.3
-
175
-
-
85047690934
-
Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation
-
Tessner T.G., Muhale F., Riehl T.E., Anant S., Stenson W.F. Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation. J. Clin. Invest. 2004, 114:1676-1685.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1676-1685
-
-
Tessner, T.G.1
Muhale, F.2
Riehl, T.E.3
Anant, S.4
Stenson, W.F.5
-
176
-
-
33744914050
-
Evolving concepts of apoptosis in idiopathic pulmonary fibrosis
-
Thannickal V.J., Horowitz J.C. Evolving concepts of apoptosis in idiopathic pulmonary fibrosis. Proc. Am. Thorac. Soc. 2006, 3:350-356.
-
(2006)
Proc. Am. Thorac. Soc.
, vol.3
, pp. 350-356
-
-
Thannickal, V.J.1
Horowitz, J.C.2
-
177
-
-
0034650330
-
Activation of peroxisome proliferator-activated receptor gamma does not inhibit IL-6 or TNF-alpha responses of macrophages to lipopolysaccharide in vitro or in vivo
-
Thieringer R., Fenyk-Melody J.E., Le Grand C.B., Shelton B.A., Detmers P.A., Somers E.P., Carbin L., Moller D.E., Wright S.D., Berger J. Activation of peroxisome proliferator-activated receptor gamma does not inhibit IL-6 or TNF-alpha responses of macrophages to lipopolysaccharide in vitro or in vivo. J. Immunol. 2000, 164:1046-1054.
-
(2000)
J. Immunol.
, vol.164
, pp. 1046-1054
-
-
Thieringer, R.1
Fenyk-Melody, J.E.2
Le Grand, C.B.3
Shelton, B.A.4
Detmers, P.A.5
Somers, E.P.6
Carbin, L.7
Moller, D.E.8
Wright, S.D.9
Berger, J.10
-
178
-
-
0035065836
-
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
-
Tobiume K., Matsuzawa A., Takahashi T., Nishitoh H., Morita K., Takeda K., Minowa O., Miyazono K., Noda T., Ichijo H. ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep. 2001, 2:222-228.
-
(2001)
EMBO Rep.
, vol.2
, pp. 222-228
-
-
Tobiume, K.1
Matsuzawa, A.2
Takahashi, T.3
Nishitoh, H.4
Morita, K.5
Takeda, K.6
Minowa, O.7
Miyazono, K.8
Noda, T.9
Ichijo, H.10
-
179
-
-
0034809490
-
Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2
-
Tsubouchi Y., Kawahito Y., Kohno M., Inoue K., Hla T., Sano H. Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2. Biochem. Biophys. Res. Commun. 2001, 283:750-755.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.283
, pp. 750-755
-
-
Tsubouchi, Y.1
Kawahito, Y.2
Kohno, M.3
Inoue, K.4
Hla, T.5
Sano, H.6
-
180
-
-
0028803728
-
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
-
Tsujii M., DuBois R.N. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995, 83:493-501.
-
(1995)
Cell
, vol.83
, pp. 493-501
-
-
Tsujii, M.1
DuBois, R.N.2
-
181
-
-
38949126129
-
15-Deoxy-12,14-prostaglandin J2: an electrophilic trigger of cellular responses
-
Uchida K., Shibata T. 15-Deoxy-12,14-prostaglandin J2: an electrophilic trigger of cellular responses. Chem. Res. Toxicol. 2008, 21:138-144.
-
(2008)
Chem. Res. Toxicol.
, vol.21
, pp. 138-144
-
-
Uchida, K.1
Shibata, T.2
-
182
-
-
0027331413
-
Thromboxane A2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis
-
Ushikubi F., Aiba Y., Nakamura K., Namba T., Hirata M., Mazda O., Katsura Y., Narumiya S. Thromboxane A2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis. J. Exp. Med. 1993, 178:1825-1830.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1825-1830
-
-
Ushikubi, F.1
Aiba, Y.2
Nakamura, K.3
Namba, T.4
Hirata, M.5
Mazda, O.6
Katsura, Y.7
Narumiya, S.8
-
183
-
-
76849095665
-
The role of COX-2 in intestinal inflammation and colorectal cancer
-
Wang D., DuBois R.N. The role of COX-2 in intestinal inflammation and colorectal cancer. Oncogene 2009, 29:781-788.
-
(2009)
Oncogene
, vol.29
, pp. 781-788
-
-
Wang, D.1
DuBois, R.N.2
-
185
-
-
84855452538
-
Epoxyeicosatrienoic acids: a double-edged sword in cardiovascular diseases and cancer
-
Wang D., DuBois R.N. Epoxyeicosatrienoic acids: a double-edged sword in cardiovascular diseases and cancer. J. Clin. Invest. 2012, 122:19-22.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 19-22
-
-
Wang, D.1
DuBois, R.N.2
-
186
-
-
4544320012
-
Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta
-
Wang D., Wang H., Shi Q., Katkuri S., Walhi W., Desvergne B., Das S.K., Dey S.K., DuBois R.N. Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer Cell 2004, 6:285-295.
-
(2004)
Cancer Cell
, vol.6
, pp. 285-295
-
-
Wang, D.1
Wang, H.2
Shi, Q.3
Katkuri, S.4
Walhi, W.5
Desvergne, B.6
Das, S.K.7
Dey, S.K.8
DuBois, R.N.9
-
187
-
-
49149130029
-
The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation
-
Wang L., Azad N., Kongkaneramit L., Chen F., Lu Y., Jiang B.H., Rojanasakul Y. The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation. J. Immunol. 2008, 180:3072-3080.
-
(2008)
J. Immunol.
, vol.180
, pp. 3072-3080
-
-
Wang, L.1
Azad, N.2
Kongkaneramit, L.3
Chen, F.4
Lu, Y.5
Jiang, B.H.6
Rojanasakul, Y.7
-
188
-
-
0037096205
-
Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism
-
Ward C., Dransfield I., Murray J., Farrow S.N., Haslett C., Rossi A.G. Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism. J. Immunol. 2002, 168:6232-6243.
-
(2002)
J. Immunol.
, vol.168
, pp. 6232-6243
-
-
Ward, C.1
Dransfield, I.2
Murray, J.3
Farrow, S.N.4
Haslett, C.5
Rossi, A.G.6
-
189
-
-
0027406849
-
Molecular cloning of a 12-lipoxygenase cDNA from rat brain
-
Watanabe T., Medina J.F., Haeggstrom J.Z., Radmark O., Samuelsson B. Molecular cloning of a 12-lipoxygenase cDNA from rat brain. Eur. J. Biochem. 1993, 212:605-612.
-
(1993)
Eur. J. Biochem.
, vol.212
, pp. 605-612
-
-
Watanabe, T.1
Medina, J.F.2
Haeggstrom, J.Z.3
Radmark, O.4
Samuelsson, B.5
-
190
-
-
27744513891
-
Expression of thromboxane synthase, TBXAS1 and the thromboxane A2 receptor, TBXA2R, in human breast cancer
-
Watkins G., Douglas-Jones A., Mansel R.E., Jiang W.G. Expression of thromboxane synthase, TBXAS1 and the thromboxane A2 receptor, TBXA2R, in human breast cancer. Int. Semin. Surg. Oncol. 2005, 2:23.
-
(2005)
Int. Semin. Surg. Oncol.
, vol.2
, pp. 23
-
-
Watkins, G.1
Douglas-Jones, A.2
Mansel, R.E.3
Jiang, W.G.4
-
191
-
-
0035957653
-
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
-
Wei M.C., Zong W.X., Cheng E.H., Lindsten T., Panoutsakopoulou V., Ross A.J., Roth K.A., MacGregor G.R., Thompson C.B., Korsmeyer S.J. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 2001, 292:727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
192
-
-
56349145549
-
TLR4/MYD88-dependent, LPS-induced synthesis of PGE2 by macrophages or dendritic cells prevents anti-CD3-mediated CD95L upregulation in T cells
-
Weinlich R., Bortoluci K.R., Chehab C.F., Serezani C.H., Ulbrich A.G., Peters-Golden M., Russo M., Amarante-Mendes G.P. TLR4/MYD88-dependent, LPS-induced synthesis of PGE2 by macrophages or dendritic cells prevents anti-CD3-mediated CD95L upregulation in T cells. Cell Death Differ. 2008, 15:1901-1909.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 1901-1909
-
-
Weinlich, R.1
Bortoluci, K.R.2
Chehab, C.F.3
Serezani, C.H.4
Ulbrich, A.G.5
Peters-Golden, M.6
Russo, M.7
Amarante-Mendes, G.P.8
-
193
-
-
13244258341
-
Prostaglandin E(2) inhibits fibroblast migration by E-prostanoid 2 receptor-mediated increase in PTEN activity
-
White E.S., Atrasz R.G., Dickie E.G., Aronoff D.M., Stambolic V., Mak T.W., Moore B.B., Peters-Golden M. Prostaglandin E(2) inhibits fibroblast migration by E-prostanoid 2 receptor-mediated increase in PTEN activity. Am. J. Respir. Cell Mol. Biol. 2005, 32:135-141.
-
(2005)
Am. J. Respir. Cell Mol. Biol.
, vol.32
, pp. 135-141
-
-
White, E.S.1
Atrasz, R.G.2
Dickie, E.G.3
Aronoff, D.M.4
Stambolic, V.5
Mak, T.W.6
Moore, B.B.7
Peters-Golden, M.8
-
194
-
-
0034805226
-
A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma
-
Wilmer W.A., Dixon C., Lu L., Hilbelink T., Rovin B.H. A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma. Biochem. Biophys. Res. Commun. 2001, 281:57-62.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.281
, pp. 57-62
-
-
Wilmer, W.A.1
Dixon, C.2
Lu, L.3
Hilbelink, T.4
Rovin, B.H.5
-
195
-
-
0034811654
-
12-Lipoxygenase inhibition induced apoptosis in human gastric cancer cells
-
Wong B.C., Wang W.P., Cho C.H., Fan X.M., Lin M.C., Kung H.F., Lam S.K. 12-Lipoxygenase inhibition induced apoptosis in human gastric cancer cells. Carcinogenesis 2001, 22:1349-1354.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1349-1354
-
-
Wong, B.C.1
Wang, W.P.2
Cho, C.H.3
Fan, X.M.4
Lin, M.C.5
Kung, H.F.6
Lam, S.K.7
-
196
-
-
67650354231
-
Cyclooxygenase inhibitors induce colon cancer cell apoptosis Via PPARdelta -> 14-3-3epsilon pathway
-
Wu K.K., Liou J.Y. Cyclooxygenase inhibitors induce colon cancer cell apoptosis Via PPARdelta -> 14-3-3epsilon pathway. Methods Mol. Biol. 2009, 512:295-307.
-
(2009)
Methods Mol. Biol.
, vol.512
, pp. 295-307
-
-
Wu, K.K.1
Liou, J.Y.2
-
197
-
-
79959934494
-
The roles of CYP450 epoxygenases and metabolites, epoxyeicosatrienoic acids, in cardiovascular and malignant diseases
-
Xu X., Zhang X.A., Wang D.W. The roles of CYP450 epoxygenases and metabolites, epoxyeicosatrienoic acids, in cardiovascular and malignant diseases. Adv. Drug Deliv. Rev. 2011, 63:597-609.
-
(2011)
Adv. Drug Deliv. Rev.
, vol.63
, pp. 597-609
-
-
Xu, X.1
Zhang, X.A.2
Wang, D.W.3
-
198
-
-
34547135686
-
Cytochrome P-450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-α via MAPK and PI3K/Akt signaling pathways
-
Yang S., Lin L., Chen J.-X., Lee C.R., Seubert J.M., Wang Y., Wang H., Chao Z.-R., Tao D.-D., Gong J.-P., Lu Z.-Y., Wang D.W., Zeldin D.C. Cytochrome P-450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-α via MAPK and PI3K/Akt signaling pathways. Am. J. Physiol. Heart Circ. Physiol. 2007, 293:H142-H151.
-
(2007)
Am. J. Physiol. Heart Circ. Physiol.
, vol.293
-
-
Yang, S.1
Lin, L.2
Chen, J.-X.3
Lee, C.R.4
Seubert, J.M.5
Wang, Y.6
Wang, H.7
Chao, Z.-R.8
Tao, D.-D.9
Gong, J.-P.10
Lu, Z.-Y.11
Wang, D.W.12
Zeldin, D.C.13
-
199
-
-
80054089650
-
Free radical lipid peroxidation: mechanisms and analysis
-
Yin H., Xu L., Porter N.A. Free radical lipid peroxidation: mechanisms and analysis. Chem. Rev. 2011, 111:5944-5972.
-
(2011)
Chem. Rev.
, vol.111
, pp. 5944-5972
-
-
Yin, H.1
Xu, L.2
Porter, N.A.3
-
200
-
-
0036480250
-
Thromboxane synthase inhibitors induce apoptosis in migration-arrested glioma cells
-
Yoshizato K., Zapf S., Westphal M., Berens M.E., Giese A. Thromboxane synthase inhibitors induce apoptosis in migration-arrested glioma cells. Neurosurgery 2002, 50:343-354.
-
(2002)
Neurosurgery
, vol.50
, pp. 343-354
-
-
Yoshizato, K.1
Zapf, S.2
Westphal, M.3
Berens, M.E.4
Giese, A.5
-
201
-
-
67650073361
-
Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity
-
Zhang Y., El-Sikhry H., Chaudhary K.R., Batchu S.N., Shayeganpour A., Jukar T.O., Bradbury J.A., Graves J.P., DeGraff L.M., Myers P., Rouse D.C., Foley J., Nyska A., Zeldin D.C., Seubert J.M. Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity. Am. J. Physiol. Heart Circ. Physiol. 2009, 297:H37-H46.
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.297
-
-
Zhang, Y.1
El-Sikhry, H.2
Chaudhary, K.R.3
Batchu, S.N.4
Shayeganpour, A.5
Jukar, T.O.6
Bradbury, J.A.7
Graves, J.P.8
DeGraff, L.M.9
Myers, P.10
Rouse, D.C.11
Foley, J.12
Nyska, A.13
Zeldin, D.C.14
Seubert, J.M.15
-
202
-
-
84864365143
-
Delivery of AAV2-CYP2J2 protects remnant kidney in the 5/6-nephrectomized rat via inhibition of apoptosis and fibrosis
-
Zhao G., Tu L., Li X., Yang S., Chen C., Xu X., Wang P., Wang D.W. Delivery of AAV2-CYP2J2 protects remnant kidney in the 5/6-nephrectomized rat via inhibition of apoptosis and fibrosis. Hum. Gene Ther. 2012, 23(7):688-699.
-
(2012)
Hum. Gene Ther.
, vol.23
, Issue.7
, pp. 688-699
-
-
Zhao, G.1
Tu, L.2
Li, X.3
Yang, S.4
Chen, C.5
Xu, X.6
Wang, P.7
Wang, D.W.8
-
203
-
-
80053358354
-
PGI synthase overexpression protects against bleomycin-induced mortality and is associated with increased Nqo 1 expression
-
Zhou W., Dowell D.R., Geraci M.W., Blackwell T.S., Collins R.D., Polosukhin V.V., Lawson W.E., Wu P., Sussan T., Biswal S., Goleniewska K., O'Neal J., Newcomb D.C., Toki S., Morrow J.D., Peebles R.S. PGI synthase overexpression protects against bleomycin-induced mortality and is associated with increased Nqo 1 expression. Am. J. Physiol. Lung Cell. Mol. Physiol. 2011, 301:L615-L622.
-
(2011)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.301
-
-
Zhou, W.1
Dowell, D.R.2
Geraci, M.W.3
Blackwell, T.S.4
Collins, R.D.5
Polosukhin, V.V.6
Lawson, W.E.7
Wu, P.8
Sussan, T.9
Biswal, S.10
Goleniewska, K.11
O'Neal, J.12
Newcomb, D.C.13
Toki, S.14
Morrow, J.D.15
Peebles, R.S.16
-
204
-
-
77954659915
-
Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases
-
Zhu F., Wang P., Kontrogianni-Konstantopoulos A., Konstantopoulos K. Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases. Cell Death Differ. 2010, 17:1325-1334.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 1325-1334
-
-
Zhu, F.1
Wang, P.2
Kontrogianni-Konstantopoulos, A.3
Konstantopoulos, K.4
-
205
-
-
0033558215
-
The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis
-
Zong W.X., Edelstein L.C., Chen C., Bash J., Gelinas C. The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis. Genes Dev. 1999, 13:382-387.
-
(1999)
Genes Dev.
, vol.13
, pp. 382-387
-
-
Zong, W.X.1
Edelstein, L.C.2
Chen, C.3
Bash, J.4
Gelinas, C.5
-
206
-
-
81255165663
-
Tyrosine nitration of prostacyclin synthase is associated with enhanced retinal cell apoptosis in diabetes
-
Zou M.-H., Li H., He C., Lin M., Lyons T.J., Xie Z. Tyrosine nitration of prostacyclin synthase is associated with enhanced retinal cell apoptosis in diabetes. Am. J. Pathol. 2011, 179:2835-2844.
-
(2011)
Am. J. Pathol.
, vol.179
, pp. 2835-2844
-
-
Zou, M.-H.1
Li, H.2
He, C.3
Lin, M.4
Lyons, T.J.5
Xie, Z.6
|