Minimal BH3 peptides promote cell death by antagonizing anti-apoptotic proteins

Journal of Biological Chemistry

Volumn 278, Issue 21, 2003, Pages 19426-19435

  Moreau, Carole ^a   Cartron, Pierre François ^a   Hunt, Abigail ^b   Meflah, Khaled ^a   Green, Douglas R ^c   Evan, Gerard ^b   Vallette, François M ^a   Juin, Philippe ^a  

^a INSERM   (France)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CONFORMATIONS; NITROGEN COMPOUNDS;

APOPTOSIS;

PROTEINS;

APOPTOSIS INDUCING FACTOR; APOPTOSIS INHIBITOR; PEPTIDE; PEPTIDE BH3; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; BAK1 PROTEIN, RAT; BAX PROTEIN (53 86); BAX PROTEIN (53-86); BAX PROTEIN, RAT; BCL2L1 PROTEIN, RAT; MEMBRANE PROTEIN; ONCOPROTEIN; PEPTIDE FRAGMENT; PROTEIN BCL X;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; MITOCHONDRION; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; CYTOLOGY; DIMERIZATION; DRUG ANTAGONISM; DRUG EFFECT; FIBROBLAST; GENE EXPRESSION; GENETIC TRANSFECTION; KINETICS; LIVER MITOCHONDRION; METABOLISM; MICROINJECTION; MOLECULAR GENETICS; PROTEIN CONFORMATION;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CELL LINE; DIMERIZATION; FIBROBLASTS; GENE EXPRESSION; KINETICS; MEMBRANE PROTEINS; MICROINJECTIONS; MITOCHONDRIA, LIVER; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 0038304520     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209472200     Document Type: Article

References (47)

1. Green, D. R. (2000) Cell 102, 1-4
2. Adams, J. M., and Cory, S. (1998) Science 281, 1322-1326
3. Degterev, A., Boyce, M., and Yuan, J. (2001) J. Cell Biol. 155, 695-698
4. Oltvai, Z., Milliman, C., and Korsmeyer, S. (1993) Cell 74, 609-619
5. Sattler, M., Liang, H., Nettesheim, D., Meadows, R. P., Harlan, J. E., Eberstadt, M., Yoon, H. S., Shuker, S. B., Chang, B. S., Minn, A. J., Thompson, C. B., and Fesik, S. W. (1997) Science 275, 983-986
6. Degterev, A., Lugovskoy, A., Cardone, M., Mulley, B., Wagner, G., Mitchison, T., and Yuan, J. (2001) Nat. Cell Biol. 3, 173-182
7. Kelekar, A., and Thompson, C. (1998) Trends Cell Biol. 8, 324-330
8. Hunt, A., and Evan, G. (2001) Science 293, 1784-1785
9. Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., Yamashita, T., Tokino, T., Taniguchi, T., and Tanaka, N. (2000) Science 288, 1053-1058
10. Yu, J., Zhang, L., Hwang, P., Kinzler, K., and Vogelstein, B. (2001) Mol. Cell 7, 673-682
11. Nakano, K., and Vousden, K. H. (2001) Mol. Cell 7, 683-694
12. Li, H., Zhu, H., Xu, C. J., and Yuan, J. (1998) Cell 94, 491-501
13. Luo, X., Budihardjo, I., Zou, H., Slaughter, C., and Wang, X. (1998) Cell 94, 481-490
14. Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. E. (1997) Cell 91, 231-241
15. Wei, M. C., Zong, W. X., Cheng, E. H., Lindsten, T., Panoutsakopoulou, V., Ross, A. J., Roth, K. A., MacGregor, G. R., Thompson, C. B., and Korsmeyer, S. J. (2001) Science 292, 727-730
16. Zong, W. X., Lindsten, T., Ross, A. J., MacGregor, G. R., and Thompson, C. B. (2001) Genes Dev. 15, 1481-1486
17. Cheng, E. H., Wei, M. C., Weiler, S., Flavell, R. A., Mak, T. W., Lindsten, T., and Korsmeyer, S. J. (2001) Mol. Cell 8, 705-711
18. Wolter, K. G., Hsu, Y. T., Smith, C. L., Nechushtan, A., Xi, X. G., and Youle, R. J. (1997) J. Cell Biol. 139, 1281-1292
19. Wang, K., Yin, X. M., Chao, D. T., Milliman, C. L., and Korsmeyer, S. J. (1996) Genes Dev. 10, 2859-2869
20. Desagher, S., Osen-Sand, A., Nichols, A., Eskes, R., Montessuit, S., Lauper, S., Maundrell, K., Antonsson, B., and Martinou, J. C. (1999) J. Cell Biol. 144, 891-901
21. Korsmeyer, S. J., Wei, M. C., Saito, M., Weiler, S., Oh, K. J., and Schlesinger, P. H. (2000) Cell Death Differ. 7, 1166-1173
22. Letai, A., Bassik, M., Walensky, L., Sorcinelli, M., Weiler, S., and Korsmeyer, S. (2002) Cancer Cell 2, 183-192
23. Kuwana, T., Mackey, M. R., Perkins, G., Ellisman, M. H., Latterich, M., Schneiter, R., Green, D. R., and Newmeyer, D. D. (2002) Cell 111, 331-342
24. Juin, P., Hunt, A., Littlewood, T., Griffiths, B., Brown, L., Korsmeyer, S., and Evan, G. (2002) Mol. Cell. Biol. 22, 6158-6169
25. Cartron, P. F., Moreau, C., Oliver, L., Mayat, E., Meflah, K., and Vallette, F. M. (2002) FEBS Lett. 512, 95-100
26. von Ahsen, O., Renken, C., Perkins, G., Kluck, R. M., Bossy-Wetzel, E., and Newmeyer, D. D. (2000) J. Cell Biol. 150, 1027-1036
27. Juin, P., Hueber, A. O., Littlewood, T., and Evan, G. (1999) Genes Dev. 13, 1367-1381
28. Tremblais, K., Oliver, L., Juin, P., Le Cabellec, T. M., Meflah, K., and Vallette, F. M. (1999) Biochem. Biophys. Res. Commun. 260, 582-591
29. Cosulich, S. C., Worrall, V., Hedge, P. J., Green, S., and Clarke, P. R. (1997) Curr. Biol. 7, 913-920
30. Antonsson, B., Montessuit, S., Lauper, S., Eskes, R., and Martinou, J. C. (2000) Biochem. J. 345, 271-278
31. Madesh, M., Antonsson, B., Srinivasula, S. M., Alnemri, E. S., and Hajnoczky, G. (2002) J. Biol. Chem. 277, 5651-5659
32. Ruffolo, S. C., Breckenridge, D. G., Nguyen, M., Goping, I. S., Gross, A., Korsmeyer, S. J., Li, H., Yuan, J., and Shore, G. C. (2000) Cell Death Differ. 7, 1101-1108
33. Nomura, M., Shimizu, S., Ito, T., Narita, M., Matsuda, H., and Tsujimoto, Y. (1999) Cancer Res. 59, 5542-5548
34. Goping, I. S., Gross, A., Lavoie, J. N., Nguyen, M., Jemmerson, R., Roth, K., Korsmeyer, S. J., and Shore, G. C. (1998) J. Cell Biol. 143, 207-215
35. Perez, D., and White, E. (2000) Mol. Cell 6, 53-63
36. Cartron, P. F., Oliver, L., Martin, S., Moreau, C., LeCabellec, M. T., Jezequel, P., Meflah, K., and Vallette, F. M. (2002) Hum. Mol. Genet. 11, 675-687
37. Hsu, Y.-T., Wolter, K. G., and Youle, R. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 3668-3672
38. Hsu, Y. T., and Youle, R. J. (1997) J. Biol. Chem. 272, 13829-13834
39. Shangary, S., and Johnson, D. E. (2002) Biochemistry 41, 9485-9495
40. Finnegan, N. M., Curtin, J. F., Prevost, G., Morgan, B., and Cotter, T. G. (2001) Br. J. Cancer 85, 115-121
41. Terradillos, O., Montessuit, S., Huang, D. C., and Martinou, J. C. (2002) FEBS Lett. 522, 29-34
42. Eskes, R., Desagher, S., Antonsson, B., and Martinou, J. C. (2000) Mol. Cell. Biol. 20, 929-935
43. Gross, A., Jockel, J., Wei, M. C., and Korsmeyer, S. J. (1998) EMBO J. 17, 3878-3885
44. Mahajan, N. P., Linder, K., Berry, G., Gordon, G. W., Heim, R., and Herman, B. (1998) Nat. Biotechnol. 16, 547-552
45. Enyedy, I. J., Ling, Y., Nacro, K., Tomita, Y., Wu, X., Cao, Y., Guo, R., Li, B., Zhu, X., Huang, Y., Long, Y. Q., Roller, P. P., Yang, D., and Wang, S. (2001) J. Med. Chem. 44, 4313-4324
46. Suzuki, M., Youle, R. J., and Tjandra, N. (2000) Cell 103, 645-654
47. Tzung, S. P., Kim, K. M., Basanez, G., Giedt, C. D., Simon, J., Zimmerberg, J., Zhang, K. Y., and Hockenbery, D. M. (2001) Nat. Cell Biol. 3, 183-191