Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 22, 1998, Pages 13182-13187

  Ghosh, Jagadananda ^a   Myers, Charles E ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; 5 HYDROXYICOSATETRAENOIC ACID; ACETYLCYSTEINE; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID;

APOPTOSIS; ARTICLE; CANCER RISK; ENZYME ACTIVITY; ENZYME INHIBITION; FAT INTAKE; HORMONE RESPONSE; HUMAN; HUMAN CELL; MALE; MITOGENESIS; MOLECULAR DYNAMICS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTATE CANCER;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ANTINEOPLASTIC AGENTS; APOPTOSIS; ARACHIDONATE 5-LIPOXYGENASE; CELL MEMBRANE; DIETARY FATS; DRUGS, CHINESE HERBAL; FLAVANONES; FLAVONOIDS; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; IBUPROFEN; INDOLES; LEUKOTRIENE B4; LIPOXYGENASE INHIBITORS; MALE; MITOCHONDRIA; MODELS, BIOLOGICAL; NUCLEOSOMES; OXIDATIVE STRESS; PERMEABILITY; PHOSPHATIDYLSERINES; PROSTATIC NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0032573175     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.22.13182     Document Type: Article

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