Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 294, Issue 2, 2008, Pages

  Dhanasekaran, Anuradha ^a   Gruenloh, Stephanie K ^a   Buonaccorsi, J Noelle ^b   Zhang, Rong ^a   Gross, Garrett J ^b   Falck, John R ^c   Patel, Paresh K ^c   Jacobs, Elizabeth R ^a   Medhora, Meetha ^a,d  

^a Cardiovascular Research Center   (United States)

^b Department of Pharmacology and Toxicology ^*  (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Caspase; Fatty acids; Ischemia; Mouse; Rat

Indexed keywords

CASPASE 3; CASPASE 9; EPOXYICOSATRIENOIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; POTASSIUM CHANNEL; PROTEIN BAD; PROTEIN BCL XL; PROTEIN KINASE B;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL HYPOXIA; CELL IMMORTALIZATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART MUSCLE; HEART MUSCLE CELL; ISCHEMIA; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; REOXYGENATION; REPERFUSION INJURY; SARCOLEMMA; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANIMALS, NEWBORN; ANNEXIN A5; APOPTOSIS; BCL-X PROTEIN; BENZIMIDAZOLES; BLOTTING, WESTERN; CASPASE 3; CASPASE 9; CELL HYPOXIA; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; EICOSANOIDS; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT DYES; MYOCYTES, CARDIAC; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 39149128273     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00979.2007     Document Type: Article

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