메뉴 건너뛰기




Volumn 33, Issue , 2013, Pages 413-451

Making, baking, and breaking: The synthesis, storage, and hydrolysis of neutral lipids

Author keywords

Acyltransferase; Cholesteryl ester; Lipotoxicity; Triacylglycerol

Indexed keywords

CHOLESTEROL ESTER; DIACYLGLYCEROL; DIACYLGLYCEROL ACYLTRANSFERASE; FAT DROPLET; GLYCEROLIPID; MONOACYLGLYCEROL; PHOSPHATIDYLCHOLINE; RETINOL; TRIACYLGLYCEROL;

EID: 84880683999     PISSN: 01999885     EISSN: 15454312     Source Type: Book Series    
DOI: 10.1146/annurev-nutr-071812-161254     Document Type: Article
Times cited : (44)

References (280)
  • 1
    • 33744962185 scopus 로고    scopus 로고
    • Hormonal control of reversible translocation of perilipin B to the plasma membrane in primary human adipocytes
    • Aboulaich N, Vener AV, Stralfors P. 2006. Hormonal control of reversible translocation of perilipin B to the plasma membrane in primary human adipocytes. J. Biol. Chem. 281:11446-49
    • (2006) J. Biol. Chem. , vol.281 , pp. 11446-11449
    • Aboulaich, N.1    Vener, A.V.2    Stralfors, P.3
  • 2
    • 0034023061 scopus 로고    scopus 로고
    • Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase
    • Accad M, Smith SJ, Newland DL, Sanan DA, King LE Jr, et al. 2000. Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase J. Clin. Investig. 105:711-19
    • (2000) J. Clin. Investig. , vol.105 , pp. 711-719
    • Accad, M.1    Smith, S.J.2    Newland, D.L.3    Sanan, D.A.4    King Jr., L.E.5
  • 3
    • 0036578783 scopus 로고    scopus 로고
    • AGPAT2 ismutated in congenital generalized lipodystrophy linked to chromosome 9q34
    • Agarwal AK, Arioglu E, De Almeida S, AkkocN, Taylor SI, et al. 2002.AGPAT2 ismutated in congenital generalized lipodystrophy linked to chromosome 9q34. Nat. Genet. 31:21-23
    • (2002) Nat. Genet. , vol.31 , pp. 21-23
    • Agarwal, A.K.1    Arioglu, E.2    De Almeida, S.3    Akkoc, N.4    Taylor, S.I.5
  • 4
    • 72049114437 scopus 로고    scopus 로고
    • The skinny on fat: Lipolysis and fatty acid utilization in adipocytes
    • Ahmadian M, Duncan RE, Sul HS. 2009. The skinny on fat: lipolysis and fatty acid utilization in adipocytes. Trends Endocrinol. Metab. 20:424-28
    • (2009) Trends Endocrinol. Metab. , vol.20 , pp. 424-428
    • Ahmadian, M.1    Duncan, R.E.2    Sul, H.S.3
  • 5
    • 77951986878 scopus 로고    scopus 로고
    • Inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization
    • Alger HM, Brown JM, Sawyer JK, Kelley KL, Shah R, et al. 2010. Inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization. J. Biol. Chem. 285:14267-74
    • (2010) J. Biol. Chem. , vol.285 , pp. 14267-14274
    • Alger, H.M.1    Brown, J.M.2    Sawyer, J.K.3    Kelley, K.L.4    Shah, R.5
  • 7
    • 54049150442 scopus 로고    scopus 로고
    • Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis
    • Anderson N, Borlak J. 2008. Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis. Pharmacol. Rev. 60:311-57
    • (2008) Pharmacol. Rev. , vol.60 , pp. 311-357
    • Anderson, N.1    Borlak, J.2
  • 8
    • 0032500649 scopus 로고    scopus 로고
    • Identification of a form of acyl-CoA:cholesterol acyltransferase specific to liver and intestine in nonhuman primates
    • Anderson RA, Joyce C, Davis M, Reagan JW, Clark M, et al. 1998. Identification of a form of acyl-CoA:cholesterol acyltransferase specific to liver and intestine in nonhuman primates. J. Biol. Chem. 273:26747-54
    • (1998) J. Biol. Chem. , vol.273 , pp. 26747-26754
    • Anderson, R.A.1    Joyce, C.2    Davis, M.3    Reagan, J.W.4    Clark, M.5
  • 9
    • 0028021203 scopus 로고
    • Purification and properties of a phosphorylatable triacylglycerol lipase from the fat body of an insect, Manduca sexta
    • Arrese EL, Wells MA. 1994. Purification and properties of a phosphorylatable triacylglycerol lipase from the fat body of an insect, Manduca sexta. J. Lipid Res. 35:1652-60
    • (1994) J. Lipid Res. , vol.35 , pp. 1652-1660
    • Arrese, E.L.1    Wells, M.A.2
  • 10
    • 0037448528 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
    • Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, et al. 2003. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421:268-72
    • (2003) Nature , vol.421 , pp. 268-272
    • Ashrafi, K.1    Chang, F.Y.2    Watts, J.L.3    Fraser, A.G.4    Kamath, R.S.5
  • 11
    • 0033571069 scopus 로고    scopus 로고
    • Phosphatidic acid, a key intermediate in lipid metabolism
    • AthenstaedtK, DaumG. 1999. Phosphatidic acid, a key intermediate in lipid metabolism. Eur. J. Biochem. 266:1-16
    • (1999) Eur. J. Biochem. , vol.266 , pp. 1-16
    • Athenstaedt, K.1    Daum, G.2
  • 12
    • 0037931415 scopus 로고    scopus 로고
    • YMR313c/TGL3 encodes a novel triacylglycerol lipase located in lipid particles of Saccharomyces cerevisiae
    • Athenstaedt K, Daum G. 2003. YMR313c/TGL3 encodes a novel triacylglycerol lipase located in lipid particles of Saccharomyces cerevisiae. J. Biol. Chem. 278:23317-23
    • (2003) J. Biol. Chem. , vol.278 , pp. 23317-23323
    • Athenstaedt, K.1    Daum, G.2
  • 13
    • 27844486104 scopus 로고    scopus 로고
    • Tgl4p and Tgl5p, two triacylglycerol lipases of the yeast Saccharomyces cerevisiae, are localized to lipid particles
    • Athenstaedt K, Daum G. 2005. Tgl4p and Tgl5p, two triacylglycerol lipases of the yeast Saccharomyces cerevisiae, are localized to lipid particles. J. Biol. Chem. 280:37301-9
    • (2005) J. Biol. Chem. , vol.280 , pp. 37301-37309
    • Athenstaedt, K.1    Daum, G.2
  • 14
    • 84855883560 scopus 로고    scopus 로고
    • YPR139c/LOA1 encodes a novel lysophosphatidic acid acyltransferase associated with lipid droplets and involved in TAG homeostasis
    • Ayciriex S, Le Guedard M, Camougrand N, Velours G, Schoene M, et al. 2012. YPR139c/LOA1 encodes a novel lysophosphatidic acid acyltransferase associated with lipid droplets and involved in TAG homeostasis. Mol. Biol. Cell 23:233-46
    • (2012) Mol. Biol. Cell , vol.23 , pp. 233-246
    • Ayciriex, S.1    Le Guedard, M.2    Camougrand, N.3    Velours, G.4    Schoene, M.5
  • 16
    • 12144286591 scopus 로고    scopus 로고
    • Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver
    • Batten ML, Imanishi Y, Maeda T, Tu DC, Moise AR, et al. 2004. Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver. J. Biol. Chem. 279:10422-32
    • (2004) J. Biol. Chem. , vol.279 , pp. 10422-10432
    • Batten, M.L.1    Imanishi, Y.2    Maeda, T.3    Tu, D.C.4    Moise, A.R.5
  • 17
    • 33746819913 scopus 로고    scopus 로고
    • Liver-specific inhibition of acyl-coenzyme a:cholesterol acyltransferase 2 with antisense oligonucleotides limits atherosclerosis development in apolipoprotein B100-only low-density lipoprotein receptor-/- mice
    • Bell TA 3rd, Brown JM, Graham MJ, Lemonidis KM, Crooke RM, Rudel LL. 2006. Liver-specific inhibition of acyl-coenzyme a:cholesterol acyltransferase 2 with antisense oligonucleotides limits atherosclerosis development in apolipoprotein B100-only low-density lipoprotein receptor-/- mice. Arterioscler. Thromb. Vasc. Biol. 26:1814-20
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 1814-1820
    • Bell Iii, T.A.1    Brown, J.M.2    Graham, M.J.3    Lemonidis, K.M.4    Crooke, R.M.5    Rudel, L.L.6
  • 21
    • 0029808302 scopus 로고    scopus 로고
    • Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene
    • Benlian P, De Gennes JL, Foubert L, Zhang H, Gagne SE, HaydenM. 1996. Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene. N. Engl. J. Med. 335:848-54
    • (1996) N. Engl. J. Med. , vol.335 , pp. 848-854
    • Benlian, P.1    De Gennes, J.L.2    Foubert, L.3    Zhang, H.4    Gagne, S.E.5    Hayden, M.6
  • 22
    • 0001617185 scopus 로고
    • An undiagnosed endocrinometabolic syndrome: Report of 2 cases
    • Berardinelli W. 1954. An undiagnosed endocrinometabolic syndrome: report of 2 cases. J. Clin. Endocrinol. Metab. 14:193-204
    • (1954) J. Clin. Endocrinol. Metab. , vol.14 , pp. 193-204
    • Berardinelli, W.1
  • 23
    • 84863791960 scopus 로고    scopus 로고
    • Opposite and redundant roles of the two Drosophila perilipins in lipid mobilization
    • Bi J, Xiang Y, Chen H, Liu Z, Gronke S, et al. 2012. Opposite and redundant roles of the two Drosophila perilipins in lipid mobilization. J. Cell Sci. 125:3568-77
    • (2012) J. Cell Sci. , vol.125 , pp. 3568-3577
    • Bi, J.1    Xiang, Y.2    Chen, H.3    Liu, Z.4    Gronke, S.5
  • 24
    • 66349128492 scopus 로고    scopus 로고
    • PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores
    • Bickel PE, Tansey JT, Welte MA. 2009. PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores. Biochim. Biophys. Acta 1791:419-40
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 419-440
    • Bickel, P.E.1    Tansey, J.T.2    Welte, M.A.3
  • 25
    • 35748972649 scopus 로고    scopus 로고
    • SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity
    • Bostrom P, Andersson L, Rutberg M, Perman J, Lidberg U, et al. 2007. SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity. Nat. Cell Biol. 9:1286-93
    • (2007) Nat. Cell Biol. , vol.9 , pp. 1286-1293
    • Bostrom, P.1    Andersson, L.2    Rutberg, M.3    Perman, J.4    Lidberg, U.5
  • 26
    • 0030729552 scopus 로고    scopus 로고
    • Linkage between markers in the vicinity of the uncoupling protein 2 gene and resting metabolic rate in humans
    • Bouchard C, Perusse L, Chagnon YC, Warden C, Ricquier D. 1997. Linkage between markers in the vicinity of the uncoupling protein 2 gene and resting metabolic rate in humans. Hum. Mol. Genet. 6:1887-89
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 1887-1889
    • Bouchard, C.1    Perusse, L.2    Chagnon, Y.C.3    Warden, C.4    Ricquier, D.5
  • 27
    • 36649015243 scopus 로고    scopus 로고
    • Thematic review series: Adipocyte biology. The perilipin family of structural lipid droplet proteins: Stabilization of lipid droplets and control of lipolysis
    • Brasaemle DL. 2007. Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J. Lipid Res. 48:2547-59
    • (2007) J. Lipid Res. , vol.48 , pp. 2547-2559
    • Brasaemle, D.L.1
  • 28
    • 8744267532 scopus 로고    scopus 로고
    • Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes
    • Brasaemle DL, Dolios G, Shapiro L, Wang R. 2004. Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes. J. Biol. Chem. 279:46835-42
    • (2004) J. Biol. Chem. , vol.279 , pp. 46835-46842
    • Brasaemle, D.L.1    Dolios, G.2    Shapiro, L.3    Wang, R.4
  • 29
    • 0031443590 scopus 로고    scopus 로고
    • Overexpression of human lecithin:cholesterol acyltransferase in cholesterol-fed rabbits:LDLmetabolism and HDL metabolism are affected in a gene dose-dependent manner
    • Brousseau ME, Santamarina-Fojo S, Vaisman BL, Applebaum-Bowden D, Berard AM, et al. 1997. Overexpression of human lecithin:cholesterol acyltransferase in cholesterol-fed rabbits:LDLmetabolism and HDL metabolism are affected in a gene dose-dependent manner. J. Lipid Res. 38:2537-47
    • (1997) J. Lipid Res. , vol.38 , pp. 2537-2547
    • Brousseau, M.E.1    Santamarina-Fojo, S.2    Vaisman, B.L.3    Applebaum-Bowden, D.4    Berard, A.M.5
  • 30
    • 44849100003 scopus 로고    scopus 로고
    • Targeted depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss
    • Brown JM, Bell TA 3rd, Alger HM, Sawyer JK, Smith TL, et al. 2008. Targeted depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss. J. Biol. Chem. 283:10522-34
    • (2008) J. Biol. Chem. , vol.283 , pp. 10522-10534
    • Brown, J.M.1    Bell Iii, T.A.2    Alger, H.M.3    Sawyer, J.K.4    Smith, T.L.5
  • 31
    • 0033613147 scopus 로고    scopus 로고
    • A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
    • Brown MS, Goldstein JL. 1999. A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood. Proc. Natl. Acad. Sci. USA 96:11041-48
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11041-11048
    • Brown, M.S.1    Goldstein, J.L.2
  • 32
    • 0034529633 scopus 로고    scopus 로고
    • Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice
    • Buhman KK, Accad M, Novak S, Choi RS, Wong JS, et al. 2000. Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice. Nat. Med. 6:1341-47
    • (2000) Nat. Med. , vol.6 , pp. 1341-1347
    • Buhman, K.K.1    Accad, M.2    Novak, S.3    Choi, R.S.4    Wong, J.S.5
  • 34
    • 0032769066 scopus 로고    scopus 로고
    • Inhibition of ACAT by avasimibe decreases both VLDL and LDL apolipoprotein B production in miniature pigs
    • Burnett J.R., Wilcox LJ, Telford DE, Kleinstiver SJ, Barrett PH, et al. 1999. Inhibition of ACAT by avasimibe decreases both VLDL and LDL apolipoprotein B production in miniature pigs. J. Lipid Res. 40:1317-27
    • (1999) J. Lipid Res. , vol.40 , pp. 1317-1327
    • Burnett, J.R.1    Wilcox, L.J.2    Telford, D.E.3    Kleinstiver, S.J.4    Barrett, P.H.5
  • 35
    • 0036237635 scopus 로고    scopus 로고
    • Mutations in the midway gene disrupt a Drosophila acyl coenzyme A: Diacylglycerol acyltransferase
    • Buszczak M, Lu X, Segraves WA, Chang TY, Cooley L. 2002. Mutations in the midway gene disrupt a Drosophila acyl coenzyme A: diacylglycerol acyltransferase. Genetics 160:1511-18
    • (2002) Genetics , vol.160 , pp. 1511-1518
    • Buszczak, M.1    Lu, X.2    Segraves, W.A.3    Chang, T.Y.4    Cooley, L.5
  • 36
    • 82355171896 scopus 로고    scopus 로고
    • Targeting acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) with small molecule inhibitors for the treatment of metabolic diseases
    • Cao J, Zhou Y, Peng H, Huang X, Stahler S, et al. 2011. Targeting acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) with small molecule inhibitors for the treatment of metabolic diseases. J. Biol. Chem. 286:41838-51
    • (2011) J. Biol. Chem. , vol.286 , pp. 41838-41851
    • Cao, J.1    Zhou, Y.2    Peng, H.3    Huang, X.4    Stahler, S.5
  • 37
    • 0018676436 scopus 로고
    • Fish-eye disease. A new familial condition with massive corneal opacities and dyslipoproteinaemia
    • Carlson LA, Philipson B. 1979. Fish-eye disease. A new familial condition with massive corneal opacities and dyslipoproteinaemia. Lancet 2:922-24
    • (1979) Lancet , vol.2 , pp. 922-924
    • Carlson, L.A.1    Philipson, B.2
  • 39
    • 84861432786 scopus 로고    scopus 로고
    • Seipin: From human disease to molecular mechanism
    • Cartwright BR, Goodman JM. 2012. Seipin: from human disease to molecular mechanism. J. Lipid Res. 53:1042-55
    • (2012) J. Lipid Res. , vol.53 , pp. 1042-1055
    • Cartwright, B.R.1    Goodman, J.M.2
  • 40
    • 15444348784 scopus 로고    scopus 로고
    • ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization
    • Cases S, Novak S, Zheng YW, Myers HM, Lear SR, et al. 1998. ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization. J. Biol. Chem. 273:26755-64
    • (1998) J. Biol. Chem. , vol.273 , pp. 26755-26764
    • Cases, S.1    Novak, S.2    Zheng, Y.W.3    Myers, H.M.4    Lear, S.R.5
  • 41
    • 13144281703 scopus 로고    scopus 로고
    • Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis
    • Cases S, Smith SJ, Zheng YW, Myers HM, Lear SR, et al. 1998. Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis. Proc. Natl. Acad. Sci. USA 95:13018-23
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13018-13023
    • Cases, S.1    Smith, S.J.2    Zheng, Y.W.3    Myers, H.M.4    Lear, S.R.5
  • 42
    • 0035914356 scopus 로고    scopus 로고
    • Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members
    • Cases S, Stone SJ, Zhou P, Yen E, Tow B, et al. 2001. Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members. J. Biol. Chem. 276:38870-76
    • (2001) J. Biol. Chem. , vol.276 , pp. 38870-38876
    • Cases, S.1    Stone, S.J.2    Zhou, P.3    Yen, E.4    Tow, B.5
  • 43
    • 33748598240 scopus 로고    scopus 로고
    • The lipid-droplet proteome reveals that droplets are a protein-storage depot
    • Cermelli S, Guo Y, Gross SP, Welte MA. 2006. The lipid-droplet proteome reveals that droplets are a protein-storage depot. Curr. Biol. 16:1783-95
    • (2006) Curr. Biol. , vol.16 , pp. 1783-1795
    • Cermelli, S.1    Guo, Y.2    Gross, S.P.3    Welte, M.A.4
  • 44
    • 0027527733 scopus 로고
    • Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells
    • Chang CC, Huh HY, Cadigan KM, Chang TY. 1993. Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells. J. Biol. Chem. 268:20747-55
    • (1993) J. Biol. Chem. , vol.268 , pp. 20747-20755
    • Chang, C.C.1    Huh, H.Y.2    Cadigan, K.M.3    Chang, T.Y.4
  • 45
    • 0034623070 scopus 로고    scopus 로고
    • Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine
    • Chang CC, Sakashita N, Ornvold K, Lee O, Chang ET, et al. 2000. Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine. J. Biol. Chem. 275:28083-92
    • (2000) J. Biol. Chem. , vol.275 , pp. 28083-28092
    • Chang, C.C.1    Sakashita, N.2    Ornvold, K.3    Lee, O.4    Chang, E.T.5
  • 48
    • 0036320538 scopus 로고    scopus 로고
    • Deficiency of acyl coenzyme a:diacylglycerol acyltransferase 1 increases leptin sensitivity in murine obesity models
    • Chen H, Ladha Z, Farese RJ. 2002. Deficiency of acyl coenzyme a:diacylglycerol acyltransferase 1 increases leptin sensitivity in murine obesity models. Endocrinology 143:2893-98
    • (2002) Endocrinology , vol.143 , pp. 2893-2898
    • Chen, H.1    Ladha, Z.2    Farese, R.J.3
  • 49
    • 0038481184 scopus 로고    scopus 로고
    • Obesity resistance and enhanced glucose metabolism in mice transplanted with white adipose tissue lacking acyl CoA:diacylglycerol acyltransferase
    • Chen HC, Jensen DR, Myers HM, Eckel RH, Farese Jr. R.V. 2003. Obesity resistance and enhanced glucose metabolism in mice transplanted with white adipose tissue lacking acyl CoA:diacylglycerol acyltransferaseJ. Clin. Investig. 111 1715-22
    • (2003) J. Clin. Investig. , vol.111 , pp. 1715-1722
    • Chen, H.C.1    Jensen, D.R.2    Myers, H.M.3    Eckel, R.H.4    Farese Jr., R.V.5
  • 50
    • 0038075340 scopus 로고    scopus 로고
    • Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption
    • Cheng D, Nelson TC, Chen J, Walker SG, Wardwell-Swanson J, et al. 2003. Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption. J. Biol. Chem. 278:13611-14
    • (2003) J. Biol. Chem. , vol.278 , pp. 13611-13614
    • Cheng, D.1    Nelson, T.C.2    Chen, J.3    Walker, S.G.4    Wardwell-Swanson, J.5
  • 51
    • 4444272576 scopus 로고    scopus 로고
    • Mammalian wax biosynthesis II: Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family
    • Cheng JB, Russell DW. 2004. Mammalian wax biosynthesis II: expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family. J. Biol. Chem. 279:37798-807
    • (2004) J. Biol. Chem. , vol.279 , pp. 37798-37807
    • Cheng, J.B.1    Russell, D.W.2
  • 52
    • 84864863755 scopus 로고    scopus 로고
    • The topology of the triacylglycerol synthesizing enzyme Lro1 indicates that neutral lipids can be produced within the luminal compartment of the endoplasmic reticulum
    • Choudhary V, Jacquier N, Schneiter R. 2011. The topology of the triacylglycerol synthesizing enzyme Lro1 indicates that neutral lipids can be produced within the luminal compartment of the endoplasmic reticulum. Commun. Integr. Biol. 4:781-84
    • (2011) Commun. Integr. Biol. , vol.4 , pp. 781-784
    • Choudhary, V.1    Jacquier, N.2    Schneiter, R.3
  • 53
    • 0034752187 scopus 로고    scopus 로고
    • The LPL S447X cSNP is associated with decreased blood pressure and plasma triglycerides, and reduced risk of coronary artery disease
    • Clee SM, Loubser O, Collins J, Kastelein JJ, Hayden MR. 2001. The LPL S447X cSNP is associated with decreased blood pressure and plasma triglycerides, and reduced risk of coronary artery disease. Clin. Genet. 60:293-300
    • (2001) Clin. Genet. , vol.60 , pp. 293-300
    • Clee, S.M.1    Loubser, O.2    Collins, J.3    Kastelein, J.J.4    Hayden, M.R.5
  • 54
    • 0037155197 scopus 로고    scopus 로고
    • Lipid droplet binding and oligomerization properties of the Parkinson?s disease proteinα-synuclein
    • Cole NB, Murphy DD, Grider T, Rueter S, Brasaemle D, Nussbaum RL. 2002. Lipid droplet binding and oligomerization properties of the Parkinson?s disease proteinα-synuclein. J. Biol. Chem. 277:6344-52
    • (2002) J. Biol. Chem. , vol.277 , pp. 6344-6352
    • Cole, N.B.1    Murphy, D.D.2    Grider, T.3    Rueter, S.4    Brasaemle, D.5    Nussbaum, R.L.6
  • 55
    • 0345171460 scopus 로고    scopus 로고
    • Enzymes of triacylglycerol synthesis and their regulation
    • Coleman RA, Lee DP. 2004. Enzymes of triacylglycerol synthesis and their regulation. Prog. Lipid Res. 43:134-76
    • (2004) Prog. Lipid Res. , vol.43 , pp. 134-176
    • Coleman, R.A.1    Lee, D.P.2
  • 57
    • 33746386861 scopus 로고    scopus 로고
    • Perilipin gene variation determines higher susceptibility to insulin resistance in Asian women when consuming a high-saturated fat, lowcarbohydrate diet
    • Corella D, Qi L, Tai ES, Deurenberg-Yap M, Tan CE, et al. 2006. Perilipin gene variation determines higher susceptibility to insulin resistance in Asian women when consuming a high-saturated fat, lowcarbohydrate diet. Diabetes Care 29:1313-19
    • (2006) Diabetes Care , vol.29 , pp. 1313-1319
    • Corella, D.1    Qi, L.2    Tai, E.S.3    Deurenberg-Yap, M.4    Tan, C.E.5
  • 58
    • 33846820321 scopus 로고    scopus 로고
    • LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues
    • Dalen KT, Dahl T, Holter E, Arntsen B, Londos C, et al. 2007. LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues. Biochim. Biophys. Acta 1771:210-27
    • (2007) Biochim. Biophys. Acta , vol.1771 , pp. 210-227
    • Dalen, K.T.1    Dahl, T.2    Holter, E.3    Arntsen, B.4    Londos, C.5
  • 59
    • 3242750587 scopus 로고    scopus 로고
    • Induction of a novel class of diacylglycerol acyltransferases and triacylglycerol accumulation in Mycobacterium tuberculosis as it goes into a dormancy-like state in culture
    • Daniel J, Deb C, Dubey VS, Sirakova TD, Abomoelak B, et al. 2004. Induction of a novel class of diacylglycerol acyltransferases and triacylglycerol accumulation in Mycobacterium tuberculosis as it goes into a dormancy-like state in culture. J. Bacteriol. 186:5017-30
    • (2004) J. Bacteriol. , vol.186 , pp. 5017-5030
    • Daniel, J.1    Deb, C.2    Dubey, V.S.3    Sirakova, T.D.4    Abomoelak, B.5
  • 60
    • 0032412784 scopus 로고    scopus 로고
    • Biochemistry, cell biology andmolecular biology of lipids of Saccharomyces cerevisiae
    • Daum G, Lees ND, BardM, Dickson R. 1998. Biochemistry, cell biology andmolecular biology of lipids of Saccharomyces cerevisiae. Yeast 14:1471-510
    • (1998) Yeast , vol.14 , pp. 1471-1510
    • Daum, G.1    Lees, N.D.2    Bard, M.3    Dickson, R.4
  • 61
    • 33846501577 scopus 로고    scopus 로고
    • Dynamics of neutral lipid storage and mobilization in yeast
    • DaumG, Wagner A, Czabany T, Athenstaedt K. 2007. Dynamics of neutral lipid storage and mobilization in yeast. Biochimie 89:243-48
    • (2007) Biochimie , vol.89 , pp. 243-248
    • Daum, G.1    Wagner, A.2    Czabany, T.3    Athenstaedt, K.4
  • 62
    • 84871938822 scopus 로고    scopus 로고
    • Proof of mechanism for the DGAT1 inhibitor AZD7687: Results from a first-time-in-human single-dose study
    • Denison H, Nilsson C, Kujacic M, Lofgren L, Karlsson C, et al. 2013. Proof of mechanism for the DGAT1 inhibitor AZD7687: results from a first-time-in-human single-dose study. Diabetes Obes. Metab. 15:136-43
    • (2013) Diabetes Obes. Metab. , vol.15 , pp. 136-143
    • Denison, H.1    Nilsson, C.2    Kujacic, M.3    Lofgren, L.4    Karlsson, C.5
  • 64
    • 0026783771 scopus 로고
    • Mechanism of hormonestimulated lipolysis in adipocytes: Translocation of hormone-sensitive lipase to the lipid storage droplet
    • Egan JJ, Greenberg AS, Chang MK, Wek SA, Moos MC Jr, Londos C. 1992. Mechanism of hormonestimulated lipolysis in adipocytes: translocation of hormone-sensitive lipase to the lipid storage droplet. Proc. Natl. Acad. Sci. USA 89:8537-41
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8537-8541
    • Egan, J.J.1    Greenberg, A.S.2    Chang, M.K.3    Wek, S.A.4    Moos Jr., M.C.5    Londos, C.6
  • 65
    • 80051695513 scopus 로고    scopus 로고
    • Phosphatidate phosphatase activity plays key role in protection against fatty acid-induced toxicity in yeast
    • Fakas S, Qiu Y, Dixon JL, Han GS, Ruggles KV, et al. 2011. Phosphatidate phosphatase activity plays key role in protection against fatty acid-induced toxicity in yeast. J. Biol. Chem. 286:29074-85
    • (2011) J. Biol. Chem. , vol.286 , pp. 29074-29085
    • Fakas, S.1    Qiu, Y.2    Dixon, J.L.3    Han, G.S.4    Ruggles, K.V.5
  • 66
    • 70449769682 scopus 로고    scopus 로고
    • Lipid droplets finally get a little R-E-S-P-E-C-T
    • Farese RV Jr, Walther TC. 2009. Lipid droplets finally get a little R-E-S-P-E-C-T. Cell 139:855-60
    • (2009) Cell , vol.139 , pp. 855-860
    • Farese Jr., R.V.1    Walther, T.C.2
  • 67
    • 0035139793 scopus 로고    scopus 로고
    • Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages
    • Fazio S, Major AS, Swift LL, Gleaves LA, Accad M, et al. 2001. Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages. J. Clin. Investig. 107:163-71
    • (2001) J. Clin. Investig. , vol.107 , pp. 163-171
    • Fazio, S.1    Major, A.S.2    Swift, L.L.3    Gleaves, L.A.4    Accad, M.5
  • 68
    • 41449116419 scopus 로고    scopus 로고
    • Genome-wide analysis of sterollipid storage and trafficking in Saccharomyces cerevisiae
    • FeiW, Alfaro G, Muthusamy BP, Klaassen Z, Graham TR, et al. 2008. Genome-wide analysis of sterollipid storage and trafficking in Saccharomyces cerevisiae. Eukaryot. Cell 7:401-14
    • (2008) Eukaryot. Cell , vol.7 , pp. 401-414
    • Fei, W.1    Alfaro, G.2    Muthusamy, B.P.3    Klaassen, Z.4    Graham, T.R.5
  • 69
    • 33845900676 scopus 로고    scopus 로고
    • The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy
    • Fischer J, Lefevre C, Morava E, Mussini JM, Laforet P, et al. 2007. The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy. Nat. Genet. 39:28-30
    • (2007) Nat. Genet. , vol.39 , pp. 28-30
    • Fischer, J.1    Lefevre, C.2    Morava, E.3    Mussini, J.M.4    Laforet, P.5
  • 70
    • 84880669627 scopus 로고    scopus 로고
    • ACAT-selective and nonselective DGAT1 inhibition: Adrenocortical effects-a cross-species comparison
    • In press
    • Floettmann JE, Buckett LK, Turnbull AV, Smith T, Hallberg C, et al. 2013. ACAT-selective and nonselective DGAT1 inhibition: adrenocortical effects-a cross-species comparison. Toxicol. Pathol. In press
    • (2013) Toxicol. Pathol.
    • Floettmann, J.E.1    Buckett, L.K.2    Turnbull, A.V.3    Smith, T.4    Hallberg, C.5
  • 71
    • 0022477311 scopus 로고
    • Hormone-sensitive lipase and monoacylglycerol lipase are both required for complete degradation of adipocyte triacylglycerol
    • Fredrikson G, TornqvistH, Belfrage P. 1986. Hormone-sensitive lipase and monoacylglycerol lipase are both required for complete degradation of adipocyte triacylglycerol. Biochim. Biophys. Acta 876:288-93
    • (1986) Biochim. Biophys. Acta , vol.876 , pp. 288-293
    • Fredrikson, G.1    Tornqvist, H.2    Belfrage, P.3
  • 72
    • 34249652929 scopus 로고    scopus 로고
    • Mutation screen and association studies in the diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13
    • Friedel S, Reichwald K, Scherag A, Brumm H, Wermter AK, et al. 2007. Mutation screen and association studies in the diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13. BMC Genet. 8:17
    • (2007) BMC Genet. , vol.8 , pp. 17
    • Friedel, S.1    Reichwald, K.2    Scherag, A.3    Brumm, H.4    Wermter, A.K.5
  • 75
    • 71449099158 scopus 로고    scopus 로고
    • Sterol and diacylglycerol acyltransferase deficiency triggers fatty acid-mediated cell death
    • Garbarino J, PadamseeM, Wilcox L, Oelkers PM, D?Ambrosio D, et al. 2009. Sterol and diacylglycerol acyltransferase deficiency triggers fatty acid-mediated cell death. J. Biol. Chem. 284:30994-1005
    • (2009) J. Biol. Chem. , vol.284 , pp. 30994-31005
    • Garbarino, J.1    Padamsee, M.2    Wilcox, L.3    Oelkers, P.M.4    Dambrosio, D.5
  • 77
    • 0033305362 scopus 로고    scopus 로고
    • A gene for congenital generalized lipodystrophy maps to human chromosome 9q34
    • Garg A, Wilson R, Barnes R, Arioglu E, Zaidi Z, et al. 1999. A gene for congenital generalized lipodystrophy maps to human chromosome 9q34. J. Clin. Endocrinol. Metab. 84:3390-94
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 3390-3394
    • Garg, A.1    Wilson, R.2    Barnes, R.3    Arioglu, E.4    Zaidi, Z.5
  • 78
    • 54049155777 scopus 로고    scopus 로고
    • CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid
    • Ghosh AK, Ramakrishnan G, Chandramohan C, Rajasekharan R. 2008. CGI-58, the causative gene for Chanarin-Dorfman syndrome, mediates acylation of lysophosphatidic acid. J. Biol. Chem. 283:24525-33
    • (2008) J. Biol. Chem. , vol.283 , pp. 24525-24533
    • Ghosh, A.K.1    Ramakrishnan, G.2    Chandramohan, C.3    Rajasekharan, R.4
  • 79
    • 0014229327 scopus 로고
    • Familial serum cholesterol ester deficiency. Clinical study of a patient with a new syndrome
    • Gjone E, Norum KR. 1968. Familial serum cholesterol ester deficiency. Clinical study of a patient with a new syndrome. Acta Med. Scand. 183:107-12
    • (1968) Acta Med. Scand. , vol.183 , pp. 107-112
    • Gjone, E.1    Norum, K.R.2
  • 80
    • 0000629906 scopus 로고
    • The mechanism of the plasma cholesterol esterification reaction: Plasma fatty acid transferase
    • Glomset JA. 1962. The mechanism of the plasma cholesterol esterification reaction: plasma fatty acid transferase. Biochim. Biophys. Acta 65:128-35
    • (1962) Biochim. Biophys. Acta , vol.65 , pp. 128-135
    • Glomset, J.A.1
  • 81
    • 0013946639 scopus 로고
    • Role of plasma lecithin:cholesterol acyltransferase in the metabolism of high density lipoproteins
    • Glomset JA, JanssenET, Kennedy R, Dobbins J. 1966. Role of plasma lecithin:cholesterol acyltransferase in the metabolism of high density lipoproteins. J. Lipid Res. 7:638-48
    • (1966) J. Lipid Res. , vol.7 , pp. 638-648
    • Glomset, J.A.1    Janssen, E.T.2    Kennedy, R.3    Dobbins, J.4
  • 83
    • 33846077661 scopus 로고    scopus 로고
    • Haplotypes in the lipoprotein lipase gene influence fasting insulin and discovery of a new risk haplotype
    • GoodarziMO, Taylor KD, Guo X, Hokanson JE, Haffner SM, et al. 2007. Haplotypes in the lipoprotein lipase gene influence fasting insulin and discovery of a new risk haplotype. J. Clin. Endocrinol. Metab. 92:293-96
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 293-296
    • Goodarzi, M.O.1    Taylor, K.D.2    Guo, X.3    Hokanson, J.E.4    Haffner, S.M.5
  • 84
    • 0001225155 scopus 로고
    • The formation of cholesterol esters with rat liver enzymes
    • Goodman DS, Deykin D, Shiratori T. 1964. The formation of cholesterol esters with rat liver enzymes. J. Biol. Chem. 239:1335-44
    • (1964) J. Biol. Chem. , vol.239 , pp. 1335-1344
    • Goodman, D.S.1    Deykin, D.2    Shiratori, T.3
  • 85
    • 57649116078 scopus 로고    scopus 로고
    • The gregarious lipid droplet
    • Goodman JM. 2008. The gregarious lipid droplet. J. Biol. Chem. 283:28005-9
    • (2008) J. Biol. Chem. , vol.283 , pp. 28005-28009
    • Goodman, J.M.1
  • 86
    • 0025772167 scopus 로고
    • Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets
    • Greenberg AS, Egan JJ, Wek SA, Garty NB, Blanchette-Mackie EJ, Londos C. 1991. Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets. J. Biol. Chem. 266:11341-46
    • (1991) J. Biol. Chem. , vol.266 , pp. 11341-11346
    • Greenberg, A.S.1    Egan, J.J.2    Wek, S.A.3    Garty, N.B.4    Blanchette-Mackie, E.J.5    Londos, C.6
  • 87
    • 81755161505 scopus 로고    scopus 로고
    • Lipid particles/droplets of the yeast Saccharomyces cerevisiae revisited: Lipidome meets proteome
    • Grillitsch K, ConnerthM, Kofeler H, Arrey TN, Rietschel B, et al. 2011. Lipid particles/droplets of the yeast Saccharomyces cerevisiae revisited: lipidome meets proteome. Biochim. Biophys. Acta 1811:1165-76
    • (2011) Biochim. Biophys. Acta , vol.1811 , pp. 1165-1176
    • Grillitsch, K.1    Connerth, M.2    Kofeler, H.3    Arrey, T.N.4    Rietschel, B.5
  • 89
    • 26944489689 scopus 로고    scopus 로고
    • Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila
    • Gronke S, Mildner A, Fellert S, Tennagels N, Petry S, et al. 2005. Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila. Cell Metab. 1:323-30
    • (2005) Cell Metab. , vol.1 , pp. 323-330
    • Gronke, S.1    Mildner, A.2    Fellert, S.3    Tennagels, N.4    Petry, S.5
  • 90
    • 0025878994 scopus 로고
    • Comparative specificity of plasma lecithin:cholesterol acyltransferase from ten animal species
    • Grove D, Pownall HJ. 1991. Comparative specificity of plasma lecithin:cholesterol acyltransferase from ten animal species. Lipids 26:416-20
    • (1991) Lipids , vol.26 , pp. 416-420
    • Grove, D.1    Pownall, H.J.2
  • 91
    • 44449095056 scopus 로고    scopus 로고
    • Functional genomic screen reveals genes involved in lipid-droplet formation and utilization
    • Guo Y, Walther TC, Rao M, Stuurman N, Goshima G, et al. 2008. Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature 453:657-61
    • (2008) Nature , vol.453 , pp. 657-661
    • Guo, Y.1    Walther, T.C.2    Rao, M.3    Stuurman, N.4    Goshima, G.5
  • 93
    • 33646462136 scopus 로고    scopus 로고
    • Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
    • Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, et al. 2006. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 312:734-37
    • (2006) Science , vol.312 , pp. 734-737
    • Haemmerle, G.1    Lass, A.2    Zimmermann, R.3    Gorkiewicz, G.4    Meyer, C.5
  • 94
    • 0037085450 scopus 로고    scopus 로고
    • Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis
    • Haemmerle G, Zimmermann R, Hayn M, Theussl C, Waeg G, et al. 2002. Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis. J. Biol. Chem. 277:4806-15
    • (2002) J. Biol. Chem. , vol.277 , pp. 4806-4815
    • Haemmerle, G.1    Zimmermann, R.2    Hayn, M.3    Theussl, C.4    Waeg, G.5
  • 95
    • 79953297691 scopus 로고    scopus 로고
    • DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes
    • Harris CA, Haas JT, Streeper RS, Stone SJ, Kumari M, et al. 2011. DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes. J. Lipid Res. 52:657-67
    • (2011) J. Lipid Res. , vol.52 , pp. 657-667
    • Harris, C.A.1    Haas, J.T.2    Streeper, R.S.3    Stone, S.J.4    Kumari, M.5
  • 96
    • 70350417480 scopus 로고    scopus 로고
    • Protection of neurons from apoptosis by apolipoprotein E-containing lipoproteins does not require lipoprotein uptake and involves activation of phospholipase C-1 and inhibition of calcineurin
    • Hayashi H, Campenot RB, Vance DE, Vance JE. 2009. Protection of neurons from apoptosis by apolipoprotein E-containing lipoproteins does not require lipoprotein uptake and involves activation of phospholipase C-1 and inhibition of calcineurin. J. Biol. Chem. 284:29605-13
    • (2009) J. Biol. Chem. , vol.284 , pp. 29605-29613
    • Hayashi, H.1    Campenot, R.B.2    Vance, D.E.3    Vance, J.E.4
  • 97
    • 30744474462 scopus 로고    scopus 로고
    • Acyl-CoA: Cholesterol acyltransferase-2 gene polymorphisms and their association with plasma lipids and coronary artery disease risks
    • He X, Lu Y, Saha N, Yang H, Heng CK. 2005. Acyl-CoA: cholesterol acyltransferase-2 gene polymorphisms and their association with plasma lipids and coronary artery disease risks. Hum. Genet. 118:393-403
    • (2005) Hum. Genet. , vol.118 , pp. 393-403
    • He, X.1    Lu, Y.2    Saha, N.3    Yang, H.4    Heng, C.K.5
  • 98
    • 0031733596 scopus 로고    scopus 로고
    • Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases
    • Heid HW, Moll R, Schwetlick I, Rackwitz HR, Keenan TW. 1998. Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases. Cell Tissue Res. 294:309-21
    • (1998) Cell Tissue Res. , vol.294 , pp. 309-321
    • Heid, H.W.1    Moll, R.2    Schwetlick, I.3    Rackwitz, H.R.4    Keenan, T.W.5
  • 99
    • 78149359508 scopus 로고    scopus 로고
    • Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1
    • Herker E, Harris C, Hernandez C, Carpentier A, Kaehlcke K, et al. 2010. Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. Nat. Med. 16:1295-98
    • (2010) Nat. Med. , vol.16 , pp. 1295-1298
    • Herker, E.1    Harris, C.2    Hernandez, C.3    Carpentier, A.4    Kaehlcke, K.5
  • 100
    • 79958815982 scopus 로고    scopus 로고
    • Unique ties between hepatitis C virus replication and intracellular lipids
    • Herker E, OttM. 2011. Unique ties between hepatitis C virus replication and intracellular lipids. Trends Endocrinol. Metab. 22:241-48
    • (2011) Trends Endocrinol. Metab. , vol.22 , pp. 241-248
    • Herker, E.1    Ott, M.2
  • 101
    • 3142640798 scopus 로고    scopus 로고
    • Structure of a lipid droplet protein: The PAT family member TIP47
    • Hickenbottom SJ, Kimmel AR, Londos C, Hurley JH. 2004. Structure of a lipid droplet protein: the PAT family member TIP47. Structure 12:1199-207
    • (2004) Structure , vol.12 , pp. 1199-1207
    • Hickenbottom, S.J.1    Kimmel, A.R.2    Londos, C.3    Hurley, J.H.4
  • 102
    • 0030049443 scopus 로고    scopus 로고
    • Lecithin:cholesterol acyltransferase overexpression generates hyperalpha-lipoproteinemia and a nonatherogenic lipoprotein pattern in transgenic rabbits
    • Hoeg JM, Vaisman BL, Demosky SJ Jr, Meyn SM, Talley GD, et al. 1996. Lecithin:cholesterol acyltransferase overexpression generates hyperalpha-lipoproteinemia and a nonatherogenic lipoprotein pattern in transgenic rabbits. J. Biol. Chem. 271:4396-402
    • (1996) J. Biol. Chem. , vol.271 , pp. 4396-4402
    • Hoeg, J.M.1    Vaisman, B.L.2    Demosky, Jr.S.J.3    Meyn, S.M.4    Talley, G.D.5
  • 103
    • 0023447931 scopus 로고
    • Hormone-sensitive lipase in brown adipose tissue: Identification and effect of cold exposure
    • Holm C, Fredrikson G, Cannon B, Belfrage P. 1987. Hormone-sensitive lipase in brown adipose tissue: identification and effect of cold exposure. Biosci. Rep. 7:897-904
    • (1987) Biosci. Rep. , vol.7 , pp. 897-904
    • Holm, C.1    Fredrikson, G.2    Cannon, B.3    Belfrage, P.4
  • 105
    • 0034965751 scopus 로고    scopus 로고
    • Efficacy and short-term safety of a new ACAT inhibitor, avasimibe, on lipids, lipoproteins, and apolipoproteins, in patients with combined hyperlipidemia
    • InsullWJr, KorenM, Davignon J, SprecherD, Schrott H, et al. 2001. Efficacy and short-term safety of a new ACAT inhibitor, avasimibe, on lipids, lipoproteins, and apolipoproteins, in patients with combined hyperlipidemia. Atherosclerosis 157:137-44
    • (2001) Atherosclerosis , vol.157 , pp. 137-144
    • Insull Jr., W.1    Koren, M.2    Davignon, J.3    Sprecher, D.4    Schrott, H.5
  • 106
    • 34547114476 scopus 로고    scopus 로고
    • Seipin/BSCL2-related motor neuron disease: Seipinopathy is a novel conformational disease associated with endoplasmic reticulum stress
    • In Japanese
    • Ito D, Suzuki N. 2007. Seipin/BSCL2-related motor neuron disease: Seipinopathy is a novel conformational disease associated with endoplasmic reticulum stress. Rinsho Shinkeigaku 47:329-35 (In Japanese
    • (2007) Rinsho Shinkeigaku , vol.47 , pp. 329-335
    • Ito, D.1    Suzuki, N.2
  • 107
    • 58849138276 scopus 로고    scopus 로고
    • Seipinopathy: A novel endoplasmic reticulum stress-associated disease
    • Ito D, Suzuki N. 2009. Seipinopathy: a novel endoplasmic reticulum stress-associated disease. Brain 132:8-15
    • (2009) Brain , vol.132 , pp. 8-15
    • Ito, D.1    Suzuki, N.2
  • 108
    • 79960398841 scopus 로고    scopus 로고
    • Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae
    • Jacquier N, Choudhary V, Mari M, Toulmay A, Reggiori F, Schneiter R. 2011. Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae. J. Cell Sci. 124:2424-37
    • (2011) J. Cell Sci. , vol.124 , pp. 2424-2437
    • Jacquier, N.1    Choudhary, V.2    Mari, M.3    Toulmay, A.4    Reggiori, F.5    Schneiter, R.6
  • 109
    • 0034879653 scopus 로고    scopus 로고
    • Transcriptional regulation of the two sterol esterification genes in the yeast Saccharomyces cerevisiae
    • Jensen-Pergakes K, Guo Z, Giattina M, Sturley SL, Bard M. 2001. Transcriptional regulation of the two sterol esterification genes in the yeast Saccharomyces cerevisiae. J. Bacteriol. 183:4950-57
    • (2001) J. Bacteriol. , vol.183 , pp. 4950-4957
    • Jensen-Pergakes, K.1    Guo, Z.2    Giattina, M.3    Sturley, S.L.4    Bard, M.5
  • 110
    • 0027303057 scopus 로고
    • Expression of hormone-sensitive lipase inmacrophage foam cells
    • PART 3
    • Jepson CA, Yeaman SJ. 1993. Expression of hormone-sensitive lipase inmacrophage foam cells. Biochem. Soc. Trans. 21(Part 3):232S
    • (1993) Biochem. Soc. Trans. , vol.21
    • Jepson, C.A.1    Yeaman, S.J.2
  • 111
    • 77950188611 scopus 로고    scopus 로고
    • Linkage and genomewide association analysis of obesity-related phenotypes: Association of weight with the MGAT1 gene
    • Johansson A, Marroni F, Hayward C, Franklin CS, Kirichenko AV, et al. 2010. Linkage and genomewide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene. Obesity (Silver Spring) 18:803-8
    • (2010) Obesity (Silver Spring , vol.18 , pp. 803-808
    • Johansson, A.1    Marroni, F.2    Hayward, C.3    Franklin, C.S.4    Kirichenko, A.V.5
  • 112
    • 67650305511 scopus 로고    scopus 로고
    • Caenorhabditis elegans as an emerging model for studying the basic biology of obesity
    • Jones KT, Ashrafi K. 2009. Caenorhabditis elegans as an emerging model for studying the basic biology of obesity. Dis. Model. Mech. 2:224-29
    • (2009) Dis. Model. Mech. , vol.2 , pp. 224-229
    • Jones, K.T.1    Ashrafi, K.2
  • 113
    • 68349093972 scopus 로고    scopus 로고
    • Analysis of neutral lipid biosynthesis in Streptomyces avermitilis MA-4680 and characterization of an acyltransferase involved herein
    • Kaddor C, Biermann K, Kalscheuer R, SteinbuchelA. 2009. Analysis of neutral lipid biosynthesis in Streptomyces avermitilis MA-4680 and characterization of an acyltransferase involved herein. Appl. Microbiol. Biotechnol. 84:143-55
    • (2009) Appl. Microbiol. Biotechnol. , vol.84 , pp. 143-155
    • Kaddor, C.1    Biermann, K.2    Kalscheuer, R.3    Steinbuchel, A.4
  • 116
    • 0037424538 scopus 로고    scopus 로고
    • A novel bifunctional wax ester synthase/acyl-CoA:diacylglycerol acyltransferase mediates wax ester and triacylglycerol biosynthesis in Acinetobacter calcoaceticus ADP1
    • Kalscheuer R, Steinbuchel A. 2003. A novel bifunctional wax ester synthase/acyl-CoA:diacylglycerol acyltransferase mediates wax ester and triacylglycerol biosynthesis in Acinetobacter calcoaceticus ADP1. J. Biol. Chem. 278:8075-82
    • (2003) J. Biol. Chem. , vol.278 , pp. 8075-8082
    • Kalscheuer, R.1    Steinbuchel, A.2
  • 117
    • 33846630830 scopus 로고    scopus 로고
    • Analysis of storage lipid accumulation in Alcanivorax borkumensis: Evidence for alternative triacylglycerol biosynthesis routes in bacteria
    • Kalscheuer R, Stoveken T, Malkus U, Reichelt R, Golyshin PN, et al. 2007. Analysis of storage lipid accumulation in Alcanivorax borkumensis: evidence for alternative triacylglycerol biosynthesis routes in bacteria. J. Bacteriol. 189:918-28
    • (2007) J. Bacteriol. , vol.189 , pp. 918-928
    • Kalscheuer, R.1    Stoveken, T.2    Malkus, U.3    Reichelt, R.4    Golyshin, P.N.5
  • 118
    • 41549146084 scopus 로고    scopus 로고
    • Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy
    • Kim CA, Delepine M, Boutet E, El Mourabit H, Le Lay S, et al. 2008. Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy. J. Clin. Endocrinol. Metab. 93:1129-34
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 1129-1134
    • Kim, C.A.1    Delepine, M.2    Boutet, E.3    El Mourabit, H.4    Le Lay, S.5
  • 119
    • 79958800838 scopus 로고    scopus 로고
    • Endoplasmic reticulum-located PDAT1-2 from castor bean enhances hydroxy fatty acid accumulation in transgenic plants
    • Kim HU, Lee KR, Go YS, Jung JH, Suh MC, Kim JB. 2011. Endoplasmic reticulum-located PDAT1-2 from castor bean enhances hydroxy fatty acid accumulation in transgenic plants. Plant Cell Physiol. 52:983-93
    • (2011) Plant Cell Physiol. , vol.52 , pp. 983-993
    • Kim, H.U.1    Lee, K.R.2    Go, Y.S.3    Jung, J.H.4    Suh, M.C.5    Kim, J.B.6
  • 120
    • 0035912744 scopus 로고    scopus 로고
    • Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
    • Kim JK, Fillmore JJ, Chen Y, Yu C, Moore IK, et al. 2001. Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc. Natl. Acad. Sci. USA 98:7522-27
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7522-7527
    • Kim, J.K.1    Fillmore, J.J.2    Chen, Y.3    Yu, C.4    Moore, I.K.5
  • 121
    • 67651046200 scopus 로고    scopus 로고
    • Diacylglycerol acyltransferase 1 inhibition lowers serum triglycerides in the Zucker fatty rat and the hyperlipidemic hamster
    • King AJ, Segreti JA, Larson KJ, Souers AJ, KymPR, et al. 2009. Diacylglycerol acyltransferase 1 inhibition lowers serum triglycerides in the Zucker fatty rat and the hyperlipidemic hamster. J. Pharmacol. Exp. Ther. 330:526-31
    • (2009) J. Pharmacol. Exp. Ther. , vol.330 , pp. 526-531
    • King, A.J.1    Segreti, J.A.2    Larson, K.J.3    Souers, A.J.4    Kym, P.R.5
  • 122
    • 0024561127 scopus 로고
    • Genetic and developmental regulation of the lipoprotein lipase gene: Loci both distal and proximal to the lipoprotein lipase structural gene control enzyme expression
    • Kirchgessner TG, LeBoeuf RC, Langner CA, Zollman S, Chang CH, et al. 1989. Genetic and developmental regulation of the lipoprotein lipase gene: Loci both distal and proximal to the lipoprotein lipase structural gene control enzyme expression. J. Biol. Chem. 264:1473-82
    • (1989) J. Biol. Chem. , vol.264 , pp. 1473-1482
    • Kirchgessner, T.G.1    Leboeuf, R.C.2    Langner, C.A.3    Zollman, S.4    Chang, C.H.5
  • 123
    • 0031796690 scopus 로고    scopus 로고
    • The putative role of the hormonesensitive lipase gene in the pathogenesis of type II diabetes mellitus and abdominal obesity
    • Klannemark M, Orho M, Langin D, Laurell H, Holm C, et al. 1998. The putative role of the hormonesensitive lipase gene in the pathogenesis of type II diabetes mellitus and abdominal obesity. Diabetologia 41:1516-22
    • (1998) Diabetologia , vol.41 , pp. 1516-1522
    • Klannemark, M.1    Orho, M.2    Langin, D.3    Laurell, H.4    Holm, C.5
  • 124
    • 80054801259 scopus 로고    scopus 로고
    • Dual role of ancient ubiquitous protein 1 (AUP1) in lipid droplet accumulation and endoplasmic reticulum (ER) protein quality control
    • Klemm EJ, Spooner E, Ploegh HL. 2011. Dual role of ancient ubiquitous protein 1 (AUP1) in lipid droplet accumulation and endoplasmic reticulum (ER) protein quality control. J. Biol. Chem. 286:37602-14
    • (2011) J. Biol. Chem. , vol.286 , pp. 37602-37614
    • Klemm, E.J.1    Spooner, E.2    Ploegh, H.L.3
  • 125
    • 14044272811 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysis
    • Koffel R, Tiwari R, Falquet L, Schneiter R. 2005. The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysis. Mol. Cell. Biol. 25:1655-68
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 1655-1668
    • Koffel, R.1    Tiwari, R.2    Falquet, L.3    Schneiter, R.4
  • 126
    • 38849096602 scopus 로고    scopus 로고
    • Imaging of lipid biosynthesis: How a neutral lipid enters lipid droplets
    • Kuerschner L, Moessinger C, Thiele C. 2008. Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets. Traffic 9:338-52
    • (2008) Traffic , vol.9 , pp. 338-352
    • Kuerschner, L.1    Moessinger, C.2    Thiele, C.3
  • 127
    • 84864835923 scopus 로고    scopus 로고
    • Lecithin:cholesterol acyltransferase: Old friend or foe in atherosclerosis?
    • Kunnen S, Van Eck M. 2012. Lecithin:cholesterol acyltransferase: old friend or foe in atherosclerosis? J. Lipid Res. 53:1783-99
    • (2012) J. Lipid Res. , vol.53 , pp. 1783-1799
    • Kunnen, S.1    Van Eck, M.2
  • 128
    • 33644853354 scopus 로고    scopus 로고
    • Obese yeast: Triglyceride lipolysis is functionally conserved from mammals to yeast
    • Kurat CF, Natter K, Petschnigg J, Wolinski H, Scheuringer K, et al. 2006. Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast. J. Biol. Chem. 281:491-500
    • (2006) J. Biol. Chem. , vol.281 , pp. 491-500
    • Kurat, C.F.1    Natter, K.2    Petschnigg, J.3    Wolinski, H.4    Scheuringer, K.5
  • 129
    • 58149308056 scopus 로고    scopus 로고
    • Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression
    • Kurat CF, Wolinski H, Petschnigg J, Kaluarachchi S, Andrews B, et al. 2009. Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression. Mol. Cell 33:53-63
    • (2009) Mol. Cell , vol.33 , pp. 53-63
    • Kurat, C.F.1    Wolinski, H.2    Petschnigg, J.3    Kaluarachchi, S.4    Andrews, B.5
  • 130
    • 79953694769 scopus 로고    scopus 로고
    • The resurgence of hormone-sensitive lipase (HSL) in mammalian lipolysis
    • Lampidonis AD, RogdakisE, VoutsinasGE, Stravopodis DJ. 2011. The resurgence of hormone-sensitive lipase (HSL) in mammalian lipolysis. Gene 477:1-11
    • (2011) Gene , vol.477 , pp. 1-11
    • Lampidonis, A.D.1    Rogdakis, E.2    Voutsinas, G.E.3    Stravopodis, D.J.4
  • 132
    • 84856656225 scopus 로고    scopus 로고
    • Characterization of the lipid droplet proteome of a clonal insulin-producing beta-cell line (INS-1 832/13
    • Larsson S, Resjo S, GomezMF, James P, Holm C. 2012. Characterization of the lipid droplet proteome of a clonal insulin-producing beta-cell line (INS-1 832/13). J. Proteome Res. 11:1264-73
    • (2012) J. Proteome Res. , vol.11 , pp. 1264-1273
    • Larsson, S.1    Resjo, S.2    Gomez, M.F.3    James, P.4    Holm, C.5
  • 133
    • 33646128723 scopus 로고    scopus 로고
    • Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman syndrome
    • Lass A, Zimmermann R, Haemmerle G, Riederer M, Schoiswohl G, et al. 2006. Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman syndrome. Cell Metab. 3:309-19
    • (2006) Cell Metab. , vol.3 , pp. 309-319
    • Lass, A.1    Zimmermann, R.2    Haemmerle, G.3    Riederer, M.4    Schoiswohl, G.5
  • 134
    • 78650107057 scopus 로고    scopus 로고
    • Lipolysis-a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
    • Lass A, Zimmermann R, Oberer M, Zechner R. 2011. Lipolysis-a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores. Prog. Lipid Res. 50:14-27
    • (2011) Prog. Lipid Res. , vol.50 , pp. 14-27
    • Lass, A.1    Zimmermann, R.2    Oberer, M.3    Zechner, R.4
  • 135
    • 0028081336 scopus 로고
    • Characterization of lipid particles of the yeast Saccharomyces cerevisiae
    • Leber R, Zinser E, Zellnig G, Paltauf F, Daum G. 1994. Characterization of lipid particles of the yeast Saccharomyces cerevisiae. Yeast 10:1421-28
    • (1994) Yeast , vol.10 , pp. 1421-1428
    • Leber, R.1    Zinser, E.2    Zellnig, G.3    Paltauf, F.4    Daum, G.5
  • 136
    • 0034764272 scopus 로고    scopus 로고
    • Mutations in CGI-58, the gene encoding a new protein of the esterase/lipase/thioesterase subfamily, in Chanarin-Dorfman syndrome
    • Lefevre C, Jobard F, Caux F, Bouadjar B, Karaduman A, et al. 2001. Mutations in CGI-58, the gene encoding a new protein of the esterase/lipase/ thioesterase subfamily, in Chanarin-Dorfman syndrome. Am. J. Hum. Genet. 69:1002-12
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 1002-1012
    • Lefevre, C.1    Jobard, F.2    Caux, F.3    Bouadjar, B.4    Karaduman, A.5
  • 137
    • 77957278964 scopus 로고    scopus 로고
    • Cell death-inducingDFF45-like effector, a lipid dropletassociated protein, might be involved in the differentiation of human adipocytes
    • Li F, GuY, DongW, Li H, ZhangL, et al. 2010. Cell death-inducingDFF45- like effector, a lipid dropletassociated protein, might be involved in the differentiation of human adipocytes. FEBS J. 277:4173-83
    • (2010) FEBS J. , vol.277 , pp. 4173-4183
    • Li, F.1    Gu, Y.2    Dong, W.3    Li, H.4    Zhang, L.5
  • 138
    • 77649336293 scopus 로고    scopus 로고
    • Control of cholesterol biosyn
    • thesis, uptake and storage in hepatocytes by Cideb
    • Li JZ, Lei Y, Wang Y, Zhang Y, Ye J, et al. 2010. Control of cholesterol biosynthesis, uptake and storage in hepatocytes by Cideb. Biochim. Biophys. Acta 1801:577-86
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 577-586
    • Li, J.Z.1    Lei, Y.2    Wang, Y.3    Zhang, Y.4    Ye, J.5
  • 139
    • 77949263134 scopus 로고    scopus 로고
    • DGAT1, DGAT2 and PDAT expression in seeds and other tissues of epoxy and hydroxy fatty acid accumulating plants
    • Li R, Yu K, Hildebrand DF. 2010. DGAT1, DGAT2 and PDAT expression in seeds and other tissues of epoxy and hydroxy fatty acid accumulating plants. Lipids 45:145-57
    • (2010) Lipids , vol.45 , pp. 145-157
    • Li, R.1    Yu, K.2    Hildebrand, D.F.3
  • 140
    • 60549104589 scopus 로고    scopus 로고
    • Molecular cloning, chromosomal location and expression pattern of porcine CIDEa and CIDEc
    • Li YH, Lei T, Chen XD, Xia T, Peng Y, et al. 2009. Molecular cloning, chromosomal location and expression pattern of porcine CIDEa and CIDEc. Mol. Biol. Rep. 36:575-82
    • (2009) Mol. Biol. Rep. , vol.36 , pp. 575-582
    • Li, Y.H.1    Lei, T.2    Chen, X.D.3    Xia, T.4    Peng, Y.5
  • 141
    • 84874209971 scopus 로고    scopus 로고
    • Characterization of a second sterol-esterifying enzyme in Toxoplasma highlights the importance of cholesterol storage pathways for the parasite
    • Lige B, SampelsV, Coppens I. 2013. Characterization of a second sterol-esterifying enzyme in Toxoplasma highlights the importance of cholesterol storage pathways for the parasite. Mol. Microbiol. 87:951-67
    • (2013) Mol. Microbiol. , vol.87 , pp. 951-967
    • Lige, B.1    Sampels, V.2    Coppens, I.3
  • 143
    • 27444431715 scopus 로고    scopus 로고
    • Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: In vitro and intact cell studies
    • Liu J, Chang CC, Westover EJ, Covey DF, Chang TY. 2005. Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: in vitro and intact cell studies. Biochem. J. 391:389-97
    • (2005) Biochem. J. , vol.391 , pp. 389-397
    • Liu, J.1    Chang, C.C.2    Westover, E.J.3    Covey, D.F.4    Chang, T.Y.5
  • 144
    • 28844503063 scopus 로고    scopus 로고
    • Disruption of the lecithin:retinol acyltransferase gene makes mice more susceptible to vitamin A deficiency
    • Liu L, Gudas LJ. 2005. Disruption of the lecithin:retinol acyltransferase gene makes mice more susceptible to vitamin A deficiency. J. Biol. Chem. 280:40226-34
    • (2005) J. Biol. Chem. , vol.280 , pp. 40226-40234
    • Liu, L.1    Gudas, L.J.2
  • 145
    • 44249109438 scopus 로고    scopus 로고
    • Homeostasis of retinol in lecithin: Retinol acyltransferase gene knockout mice fed a high retinol diet
    • Liu L, Tang XH, Gudas LJ. 2008. Homeostasis of retinol in lecithin: retinol acyltransferase gene knockout mice fed a high retinol diet. Biochem. Pharmacol. 75:2316-24
    • (2008) Biochem. Pharmacol. , vol.75 , pp. 2316-2324
    • Liu, L.1    Tang, X.H.2    Gudas, L.J.3
  • 146
    • 0942287191 scopus 로고    scopus 로고
    • Chinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane traffic
    • Liu P, Ying Y, Zhao Y, Mundy DI, Zhu M, Anderson RG. 2004. Chinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane traffic. J. Biol. Chem. 279:3787-92
    • (2004) J. Biol. Chem. , vol.279 , pp. 3787-3792
    • Liu, P.1    Ying, Y.2    Zhao, Y.3    Mundy, D.I.4    Zhu, M.5    Anderson, R.G.6
  • 147
    • 84863700580 scopus 로고    scopus 로고
    • Acyl-CoA:diacylglycerol acyltransferase: Molecular biology, biochemistry and biotechnology
    • Liu Q, Siloto RM, Lehner R, Stone SJ, Weselake RJ. 2012. Acyl-CoA:diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology. Prog. Lipid Res. 51:350-77
    • (2012) Prog. Lipid Res. , vol.51 , pp. 350-377
    • Liu, Q.1    Siloto, R.M.2    Lehner, R.3    Stone, S.J.4    Weselake, R.J.5
  • 148
    • 79953858620 scopus 로고    scopus 로고
    • Functional and topological analysis of yeast acyl-CoA:diacylglycerol acyltransferase 2, an endoplasmic reticulum enzyme essential for triacylglycerol biosynthesis
    • Liu Q, Siloto RM, Snyder CL, Weselake RJ. 2011. Functional and topological analysis of yeast acyl-CoA:diacylglycerol acyltransferase 2, an endoplasmic reticulum enzyme essential for triacylglycerol biosynthesis. J. Biol. Chem. 286:13115-26
    • (2011) J. Biol. Chem. , vol.286 , pp. 13115-13126
    • Liu, Q.1    Siloto, R.M.2    Snyder, C.L.3    Weselake, R.J.4
  • 149
    • 33846211895 scopus 로고    scopus 로고
    • Diacylglycerol acyltransferase: A key mediator of plant triacylglycerol synthesis
    • Lung SC, Weselake RJ. 2006. Diacylglycerol acyltransferase: a key mediator of plant triacylglycerol synthesis. Lipids 41:1073-88
    • (2006) Lipids , vol.41 , pp. 1073-1088
    • Lung, S.C.1    Weselake, R.J.2
  • 150
    • 0024232868 scopus 로고
    • Evidence for a lecithin-retinol acyltransferase activity in the rat small intestine
    • MacDonald PN, Ong DE. 1988. Evidence for a lecithin-retinol acyltransferase activity in the rat small intestine. J. Biol. Chem. 263:12478-82
    • (1988) J. Biol. Chem. , vol.263 , pp. 12478-12482
    • Macdonald, P.N.1    Ong, D.E.2
  • 151
    • 33745942915 scopus 로고    scopus 로고
    • Adipocyte differentiationrelated protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very lowdensity lipoproteins
    • Magnusson B, Asp L, Bostrom P, Ruiz M, Stillemark-Billton P, et al. 2006. Adipocyte differentiationrelated protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very lowdensity lipoproteins. Arterioscler. Thromb. Vasc. Biol. 26:1566-71
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 1566-1571
    • Magnusson, B.1    Asp, L.2    Bostrom, P.3    Ruiz, M.4    Stillemark-Billton, P.5
  • 152
    • 0034941121 scopus 로고    scopus 로고
    • Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13
    • Magre J, DelepineM, Khallouf E, Gedde-Dahl T Jr, Van Maldergem L, et al. 2001. Identification of the gene altered in Berardinelli-Seip congenital lipodystrophy on chromosome 11q13. Nat. Genet. 28:365-70
    • (2001) Nat. Genet. , vol.28 , pp. 365-370
    • Magre, J.1    Delepine, M.2    Khallouf, E.3    Gedde-Dahl Jr., T.4    Van Maldergem, L.5
  • 153
    • 0031912535 scopus 로고    scopus 로고
    • Human hormone-sensitive lipase: Genetic mapping, identification of a new dinucleotide repeat, and association with obesity andNIDDM
    • Magre J, Laurell H, Fizames C, Antoine PJ, Dib C, et al. 1998. Human hormone-sensitive lipase: genetic mapping, identification of a new dinucleotide repeat, and association with obesity andNIDDM. Diabetes 47:284-86
    • (1998) Diabetes , vol.47 , pp. 284-286
    • Magre, J.1    Laurell, H.2    Fizames, C.3    Antoine, P.J.4    Dib, C.5
  • 154
    • 15944365201 scopus 로고    scopus 로고
    • Caveolin, cholesterol, and lipid bodies
    • Martin S, Parton RG. 2005. Caveolin, cholesterol, and lipid bodies. Semin. Cell Dev. Biol. 16:163-74
    • (2005) Semin. Cell Dev. Biol. , vol.16 , pp. 163-174
    • Martin, S.1    Parton, R.G.2
  • 155
    • 77649224298 scopus 로고    scopus 로고
    • Aphysiological role for fat specific protein 27/cell death-inducingDFF45- like effector C in adipose and liver
    • Matsusue K. 2010.Aphysiological role for fat specific protein 27/cell death-inducingDFF45-like effector C in adipose and liver. Biol. Pharm. Bull. 33:346-50
    • (2010) Biol. Pharm. Bull. , vol.33 , pp. 346-350
    • Matsusue, K.1
  • 156
    • 41449098953 scopus 로고    scopus 로고
    • Hepatic steatosis in leptindeficient mice is promoted by the PPAR-target gene Fsp27
    • Matsusue K, Kusakabe T, Noguchi T, Takiguchi S, Suzuki T, et al. 2008. Hepatic steatosis in leptindeficient mice is promoted by the PPAR-target gene Fsp27. Cell Metab. 7:302-11
    • (2008) Cell Metab. , vol.7 , pp. 302-311
    • Matsusue, K.1    Kusakabe, T.2    Noguchi, T.3    Takiguchi, S.4    Suzuki, T.5
  • 157
    • 80051522307 scopus 로고    scopus 로고
    • Murine diacylglycerol acyltransferase-2 (DGAT2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum
    • McFie PJ, Banman SL, Kary S, Stone SJ. 2011. Murine diacylglycerol acyltransferase-2 (DGAT2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum. J. Biol. Chem. 286:28235-46
    • (2011) J. Biol. Chem. , vol.286 , pp. 28235-28246
    • McFie, P.J.1    Banman, S.L.2    Kary, S.3    Stone, S.J.4
  • 159
    • 70349898598 scopus 로고    scopus 로고
    • Adipocyte differentiationrelated protein and OXPAT in rat and human skeletal muscle: Involvement in lipid accumulation and type 2 diabetes mellitus
    • Minnaard R, Schrauwen P, Schaart G, Jorgensen JA, Lenaers E, et al. 2009. Adipocyte differentiationrelated protein and OXPAT in rat and human skeletal muscle: involvement in lipid accumulation and type 2 diabetes mellitus. J. Clin. Endocrinol. Metab. 94:4077-85
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 4077-4085
    • Minnaard, R.1    Schrauwen, P.2    Schaart, G.3    Jorgensen, J.A.4    Lenaers, E.5
  • 160
    • 34347235098 scopus 로고    scopus 로고
    • Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver
    • Monetti M, LevinMC, Watt MJ, Sajan MP, Marmor S, et al. 2007. Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. Cell Metab. 6:69-78
    • (2007) Cell Metab. , vol.6 , pp. 69-78
    • Monetti, M.1    Levin, M.C.2    Watt, M.J.3    Sajan, M.P.4    Marmor, S.5
  • 162
    • 80051809684 scopus 로고    scopus 로고
    • Deficiency of MGAT2 increases energy expenditure without high-fat feeding and protects genetically obese mice from excessive weight gain
    • Nelson DW, Gao Y, Spencer NM, Banh T, Yen CL. 2011. Deficiency of MGAT2 increases energy expenditure without high-fat feeding and protects genetically obese mice from excessive weight gain. J. Lipid Res. 52:1723-32
    • (2011) J. Lipid Res. , vol.52 , pp. 1723-1732
    • Nelson, D.W.1    Gao, Y.2    Spencer, N.M.3    Banh, T.4    Yen, C.L.5
  • 163
    • 0028179511 scopus 로고
    • The LPL gene in individuals with familial combined hyperlipidemia and decreased LPL activity
    • Nevin DN, Brunzell JD, Deeb SS. 1994. The LPL gene in individuals with familial combined hyperlipidemia and decreased LPL activity. Arterioscler. Thromb. 14:869-73
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 869-873
    • Nevin, D.N.1    Brunzell, J.D.2    Deeb, S.S.3
  • 164
    • 71149116560 scopus 로고    scopus 로고
    • Systems biology of lipid metabolism: From yeast to human
    • Nielsen J. 2009. Systems biology of lipid metabolism: from yeast to human. FEBS Lett. 583:3905-13
    • (2009) FEBS Lett. , vol.583 , pp. 3905-3913
    • Nielsen, J.1
  • 165
    • 0014513093 scopus 로고
    • The occurrence of diester waxes in human vernix caseosa and in hair lipids of common laboratory animals
    • Nikkari T. 1969. The occurrence of diester waxes in human vernix caseosa and in hair lipids of common laboratory animals. Comp. Biochem. Physiol. 29:795-803
    • (1969) Comp. Biochem. Physiol. , vol.29 , pp. 795-803
    • Nikkari, T.1
  • 167
    • 0014193805 scopus 로고
    • Familial serum-cholesterol esterification failure. A new inborn error of metabolism
    • Norum KR, Gjone E. 1967. Familial serum-cholesterol esterification failure. A new inborn error of metabolism. Biochim. Biophys. Acta 144:698-700
    • (1967) Biochim. Biophys. Acta , vol.144 , pp. 698-700
    • Norum, K.R.1    Gjone, E.2
  • 168
    • 27444438178 scopus 로고    scopus 로고
    • Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT
    • O?Byrne SM, WongsirirojN, Libien J, Vogel S, Goldberg IJ, et al. 2005. Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT). J. Biol. Chem. 280:35647-57
    • (2005) J. Biol. Chem. , vol.280 , pp. 35647-35657
    • Obyrne, S.M.1    Wongsiriroj, N.2    Libien, J.3    Vogel, S.4    Goldberg, I.J.5
  • 169
    • 0032500641 scopus 로고    scopus 로고
    • Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes
    • Oelkers P, Behari A, Cromley D, Billheimer JT, Sturley SL. 1998. Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes. J. Biol. Chem. 273:26765-71
    • (1998) J. Biol. Chem. , vol.273 , pp. 26765-26771
    • Oelkers, P.1    Behari, A.2    Cromley, D.3    Billheimer, J.T.4    Sturley, S.L.5
  • 172
    • 79955602758 scopus 로고    scopus 로고
    • Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia
    • Ohshiro T, Matsuda D, SakaiK, DegirolamoC, Yagyu H, et al. 2011. Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia. Arterioscler. Thromb. Vasc. Biol. 31:1108-15
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , pp. 1108-1115
    • Ohshiro, T.1    Matsuda, D.2    Sakai, K.3    Degirolamo, C.4    Yagyu, H.5
  • 173
    • 2442667448 scopus 로고    scopus 로고
    • The influence of the acyl-CoA:cholesterol acyltransferase-1 gene (-77G->A) polymorphisms on plasma lipid and apolipoprotein levels in normolipidemic and hyperlipidemic subjects
    • Ohta T, Takata K, Katsuren K, Fukuyama S. 2004. The influence of the acyl-CoA:cholesterol acyltransferase-1 gene (-77G->A) polymorphisms on plasma lipid and apolipoprotein levels in normolipidemic and hyperlipidemic subjects. Biochim. Biophys. Acta 1682:56-62
    • (2004) Biochim. Biophys. Acta , vol.1682 , pp. 56-62
    • Ohta, T.1    Takata, K.2    Katsuren, K.3    Fukuyama, S.4
  • 174
    • 57749110733 scopus 로고    scopus 로고
    • Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages
    • Okazaki H, Igarashi M, Nishi M, Sekiya M, Tajima M, et al. 2008. Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages. J. Biol. Chem. 283:33357-64
    • (2008) J. Biol. Chem. , vol.283 , pp. 33357-33364
    • Okazaki, H.1    Igarashi, M.2    Nishi, M.3    Sekiya, M.4    Tajima, M.5
  • 175
    • 0023203838 scopus 로고
    • Acyl-CoA-independent esterification of retinol bound to cellular retinol-binding protein (type II) by microsomes from rat small intestine
    • Ong DE, Kakkad B, MacDonald PN. 1987. Acyl-CoA-independent esterification of retinol bound to cellular retinol-binding protein (type II) by microsomes from rat small intestine. J. Biol. Chem. 262:2729-36
    • (1987) J. Biol. Chem. , vol.262 , pp. 2729-2736
    • Ong, D.E.1    Kakkad, B.2    Macdonald, P.N.3
  • 176
    • 27644498093 scopus 로고    scopus 로고
    • Acyl coenzyme A dependent retinol esterification by acyl coenzyme A: Diacylglycerol acyltransferase 1
    • Orland MD, Anwar K, Cromley D, Chu CH, Chen L, et al. 2005. Acyl coenzyme A dependent retinol esterification by acyl coenzyme A: diacylglycerol acyltransferase 1. Biochim. Biophys. Acta 1737:76-82
    • (2005) Biochim. Biophys. Acta , vol.1737 , pp. 76-82
    • Orland, M.D.1    Anwar, K.2    Cromley, D.3    Chu, C.H.4    Chen, L.5
  • 177
    • 12944335303 scopus 로고    scopus 로고
    • Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity
    • Osuga J, Ishibashi S, Oka T, Yagyu H, Tozawa R, et al. 2000. Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity. Proc. Natl. Acad. Sci. USA 97:787-92
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 787-792
    • Osuga, J.1    Ishibashi, S.2    Oka, T.3    Yagyu, H.4    Tozawa, R.5
  • 178
    • 0030957455 scopus 로고    scopus 로고
    • Overt and latent activities of diacylglycerol acyltransferase in rat liver microsomes: Possible roles in very-low-density lipoprotein triacylglycerol secretion
    • Owen MR, Corstorphine CC, Zammit VA. 1997. Overt and latent activities of diacylglycerol acyltransferase in rat liver microsomes: possible roles in very-low-density lipoprotein triacylglycerol secretion. Biochem. J. 323:17-21
    • (1997) Biochem. J. , vol.323 , pp. 17-21
    • Owen, M.R.1    Corstorphine, C.C.2    Zammit, V.A.3
  • 179
    • 48249100857 scopus 로고    scopus 로고
    • Deficiency of adipose differentiation-related protein impairs foam cell formation and protects against atherosclerosis
    • Paul A, Chang BH, Li L, Yechoor VK, Chan L. 2008. Deficiency of adipose differentiation-related protein impairs foam cell formation and protects against atherosclerosis. Circ. Res. 102:1492-501
    • (2008) Circ. Res. , vol.102 , pp. 1492-1501
    • Paul, A.1    Chang, B.H.2    Li, L.3    Yechoor, V.K.4    Chan, L.5
  • 180
    • 52649151321 scopus 로고    scopus 로고
    • Induction of stearoyl-CoA desaturase protects human arterial endothelial cells against lipotoxicity
    • Peter A, Weigert C, Staiger H, Rittig K, Cegan A, et al. 2008. Induction of stearoyl-CoA desaturase protects human arterial endothelial cells against lipotoxicity. Am. J. Physiol. Endocrinol. Metab. 295:E339-49
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.295
    • Peter, A.1    Weigert, C.2    Staiger, H.3    Rittig, K.4    Cegan, A.5
  • 181
    • 71449102613 scopus 로고    scopus 로고
    • Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast
    • Petschnigg J, Wolinski H, Kolb D, Zellnig G, Kurat CF, et al. 2009. Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast. J. Biol. Chem. 284:30981-93
    • (2009) J. Biol. Chem. , vol.284 , pp. 30981-30993
    • Petschnigg, J.1    Wolinski, H.2    Kolb, D.3    Zellnig, G.4    Kurat, C.F.5
  • 183
    • 65749089838 scopus 로고    scopus 로고
    • Lipid-inducedERstress: Synergistic effects of sterols and saturated fatty acids
    • Pineau L, Colas J, Dupont S, Beney L, Fleurat-Lessard P, et al. 2009. Lipid-inducedERstress: synergistic effects of sterols and saturated fatty acids. Traffic 10:673-90
    • (2009) Traffic , vol.10 , pp. 673-690
    • Pineau, L.1    Colas, J.2    Dupont, S.3    Beney, L.4    Fleurat-Lessard, P.5
  • 184
    • 34547216748 scopus 로고    scopus 로고
    • A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum
    • Ploegh HL. 2007. A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum. Nature 448:435-38
    • (2007) Nature , vol.448 , pp. 435-438
    • Ploegh, H.L.1
  • 185
    • 0033832729 scopus 로고    scopus 로고
    • Intracellular distribution and mobilization of unesterified cholesterol in adipocytes: Triglyceride droplets are surrounded by cholesterol-rich ER-like surface layer structures
    • Prattes S, Horl G, Hammer A, Blaschitz A, GraierWF, et al. 2000. Intracellular distribution and mobilization of unesterified cholesterol in adipocytes: Triglyceride droplets are surrounded by cholesterol-rich ER-like surface layer structures. J. Cell Sci. 113(Part 17):2977-89
    • (2000) J. Cell Sci. , vol.113 , Issue.PART 17 , pp. 2977-2989
    • Prattes, S.1    Horl, G.2    Hammer, A.3    Blaschitz, A.4    Graier, W.F.5
  • 187
    • 4844229398 scopus 로고    scopus 로고
    • Genetic variation at the perilipin (PLIN) locus is associated with obesity-related phenotypes in white women
    • Qi L, Corella D, Sorli JV, Portoles O, Shen H, et al. 2004. Genetic variation at the perilipin (PLIN) locus is associated with obesity-related phenotypes in white women. Clin. Genet. 66:299-310
    • (2004) Clin. Genet. , vol.66 , pp. 299-310
    • Qi, L.1    Corella, D.2    Sorli, J.V.3    Portoles, O.4    Shen, H.5
  • 188
    • 42949110628 scopus 로고    scopus 로고
    • Common variations in perilipin gene, central obesity, and risk of type 2 diabetes in US women
    • Qi L, Zhang C, Greenberg A, Hu FB. 2008. Common variations in perilipin gene, central obesity, and risk of type 2 diabetes in US women. Obesity (Silver Spring) 16:1061-65
    • (2008) Obesity (Silver Spring , vol.16 , pp. 1061-1065
    • Qi, L.1    Zhang, C.2    Greenberg, A.3    Hu, F.B.4
  • 189
    • 29444440400 scopus 로고    scopus 로고
    • Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction
    • Raeder H, Johansson S, Holm PI, Haldorsen IS, Mas E, et al. 2006. Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction. Nat. Genet. 38:54-62
    • (2006) Nat. Genet. , vol.38 , pp. 54-62
    • Raeder, H.1    Johansson, S.2    Holm, P.I.3    Haldorsen, I.S.4    Mas, E.5
  • 190
    • 76649108895 scopus 로고    scopus 로고
    • Janus-faced enzymes yeast Tgl3p and Tgl5p catalyze lipase and acyltransferase reactions
    • Rajakumari S, Daum G. 2010. Janus-faced enzymes yeast Tgl3p and Tgl5p catalyze lipase and acyltransferase reactions. Mol. Biol. Cell 21:501-10
    • (2010) Mol. Biol. Cell , vol.21 , pp. 501-510
    • Rajakumari, S.1    Daum, G.2
  • 191
    • 77952383445 scopus 로고    scopus 로고
    • Multiple functions as lipase, steryl ester hydrolase, phospholipase, and acyltransferase of Tgl4p from the yeast Saccharomyces cerevisiae
    • Rajakumari S, Daum G. 2010. Multiple functions as lipase, steryl ester hydrolase, phospholipase, and acyltransferase of Tgl4p from the yeast Saccharomyces cerevisiae. J. Biol. Chem. 285:15769-76
    • (2010) J. Biol. Chem. , vol.285 , pp. 15769-15776
    • Rajakumari, S.1    Daum, G.2
  • 192
    • 40849116174 scopus 로고    scopus 로고
    • Synthesis and turnover of non-polar lipids in yeast
    • Rajakumari S, Grillitsch K, Daum G. 2008. Synthesis and turnover of non-polar lipids in yeast. Prog. Lipid Res. 47:157-71
    • (2008) Prog. Lipid Res. , vol.47 , pp. 157-171
    • Rajakumari, S.1    Grillitsch, K.2    Daum, G.3
  • 193
    • 67049135868 scopus 로고    scopus 로고
    • The lipin family: Mutations and metabolism
    • Reue K. 2009. The lipin family: mutations and metabolism. Curr. Opin. Lipidol. 20:165-70
    • (2009) Curr. Opin. Lipidol. , vol.20 , pp. 165-170
    • Reue, K.1
  • 194
    • 79955531774 scopus 로고    scopus 로고
    • The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site
    • Richardson K, Louie-Gao Q, Arnett DK, Parnell LD, Lai CQ, et al. 2011. The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site. PLoS ONE 6:e17944
    • (2011) PLoS ONE , vol.6
    • Richardson, K.1    Louie-Gao, Q.2    Arnett, D.K.3    Parnell, L.D.4    Lai, C.Q.5
  • 195
    • 22544445888 scopus 로고    scopus 로고
    • Lipid droplets gain PAT family proteins by interaction with specialized plasma membrane domains
    • RobenekH, RobenekMJ, Buers I, Lorkowski S, Hofnagel O, et al. 2005. Lipid droplets gain PAT family proteins by interaction with specialized plasma membrane domains. J. Biol. Chem. 280:26330-38
    • (2005) J. Biol. Chem. , vol.280 , pp. 26330-26338
    • Robenek, H.1    Robenek, M.J.2    Buers, I.3    Lorkowski, S.4    Hofnagel, O.5
  • 197
    • 70450220107 scopus 로고    scopus 로고
    • Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC
    • Rubio-Cabezas O, Puri V, Murano I, Saudek V, Semple RK, et al. 2009. Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC. EMBO Mol. Med. 1:280-87
    • (2009) EMBO Mol. Med. , vol.1 , pp. 280-287
    • Rubio-Cabezas, O.1    Puri, V.2    Murano, I.3    Saudek, V.4    Semple, R.K.5
  • 199
    • 0037313906 scopus 로고    scopus 로고
    • Genome scan for childhood and adolescent obesity in German families
    • Saar K, Geller F, Ruschendorf F, Reis A, Friedel S, et al. 2003. Genome scan for childhood and adolescent obesity in German families. Pediatrics 111:321-27
    • (2003) Pediatrics , vol.111 , pp. 321-327
    • Saar, K.1    Geller, F.2    Ruschendorf, F.3    Reis, A.4    Friedel, S.5
  • 200
    • 0030897994 scopus 로고    scopus 로고
    • Targeted disruption of the mouse lecithin:cholesterol acyltransferase (LCAT) gene. Generation of a new animal model for human LCAT deficiency
    • Sakai N, Vaisman BL, Koch CA, Hoyt RF Jr, Meyn SM, et al. 1997. Targeted disruption of the mouse lecithin:cholesterol acyltransferase (LCAT) gene. Generation of a new animal model for human LCAT deficiency. J. Biol. Chem. 272:7506-10
    • (1997) J. Biol. Chem. , vol.272 , pp. 7506-7510
    • Sakai, N.1    Vaisman, B.L.2    Koch, C.A.3    Hoyt Jr., R.F.4    Meyn, S.M.5
  • 201
    • 0033876174 scopus 로고    scopus 로고
    • Localization of human acylcoenzyme A:cholesterol acyltransferase-1 (ACAT-1) in macrophages and in various tissues
    • Sakashita N, Miyazaki A, Takeya M, Horiuchi S, Chang CC, et al. 2000. Localization of human acylcoenzyme A:cholesterol acyltransferase-1 (ACAT-1) in macrophages and in various tissues.Am. J. Pathol. 156:227-36
    • (2000) Am. J. Pathol. , vol.156 , pp. 227-236
    • Sakashita, N.1    Miyazaki, A.2    Takeya, M.3    Horiuchi, S.4    Chang, C.C.5
  • 202
    • 0031810251 scopus 로고    scopus 로고
    • Cloning of cell-specific secreted and surface proteins by subtractive antibody screening
    • Scherer PE, Bickel PE, KotlerM, Lodish HF. 1998. Cloning of cell-specific secreted and surface proteins by subtractive antibody screening. Nat. Biotechnol. 16:581-86
    • (1998) Nat. Biotechnol. , vol.16 , pp. 581-586
    • Scherer, P.E.1    Bickel, P.E.2    Kotler, M.3    Lodish, H.F.4
  • 203
    • 33846029180 scopus 로고    scopus 로고
    • Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism
    • Schweiger M, Schreiber R, Haemmerle G, Lass A, Fledelius C, et al. 2006. Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism. J. Biol. Chem. 281:40236-41
    • (2006) J. Biol. Chem. , vol.281 , pp. 40236-40241
    • Schweiger, M.1    Schreiber, R.2    Haemmerle, G.3    Lass, A.4    Fledelius, C.5
  • 204
    • 84925556001 scopus 로고
    • Lipodystrophy and gigantism with associated endocrine manifestations. A new diencephalic syndrome?
    • Seip M. 1959. Lipodystrophy and gigantism with associated endocrine manifestations. A new diencephalic syndrome? Acta Paediatr. 48:555-74
    • (1959) Acta Paediatr. , vol.48 , pp. 555-574
    • Seip, M.1
  • 206
    • 63249133298 scopus 로고    scopus 로고
    • Retinol esterification by DGAT1 is essential for retinoid homeostasis in murine skin
    • Shih MY, Kane MA, Zhou P, Yen CL, Streeper RS, et al. 2009. Retinol esterification by DGAT1 is essential for retinoid homeostasis in murine skin. J. Biol. Chem. 284:4292-99
    • (2009) J. Biol. Chem. , vol.284 , pp. 4292-4299
    • Shih, M.Y.1    Kane, M.A.2    Zhou, P.3    Yen, C.L.4    Streeper, R.S.5
  • 207
    • 0024514407 scopus 로고
    • Hormone-sensitive lipase is responsible for the neutral cholesterol ester hydrolase activity in macrophages
    • Small CA, Goodacre JA, Yeaman SJ. 1989. Hormone-sensitive lipase is responsible for the neutral cholesterol ester hydrolase activity in macrophages. FEBS Lett. 247:205-8
    • (1989) FEBS Lett. , vol.247 , pp. 205-208
    • Small, C.A.1    Goodacre, J.A.2    Yeaman, S.J.3
  • 209
    • 0034103658 scopus 로고    scopus 로고
    • Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat
    • Smith SJ, Cases S, Jensen DR, Chen HC, Sande E, et al. 2000. Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat. Nat. Genet. 25:87-90
    • (2000) Nat. Genet. , vol.25 , pp. 87-90
    • Smith, S.J.1    Cases, S.2    Jensen, D.R.3    Chen, H.C.4    Sande, E.5
  • 210
    • 0035860725 scopus 로고    scopus 로고
    • Cholesterol esterification by host and parasite is essential for optimal proliferation of Toxoplasma gondii
    • Sonda S, Ting LM, Novak S, Kim K, Maher JJ, et al. 2001. Cholesterol esterification by host and parasite is essential for optimal proliferation of Toxoplasma gondii. J. Biol. Chem. 276:34434-40
    • (2001) J. Biol. Chem. , vol.276 , pp. 34434-34440
    • Sonda, S.1    Ting, L.M.2    Novak, S.3    Kim, K.4    Maher, J.J.5
  • 211
    • 3843131947 scopus 로고    scopus 로고
    • A yeast strain lacking lipid particles bears a defect in ergosterol formation
    • Sorger D, Athenstaedt K, Hrastnik C, Daum G. 2004. A yeast strain lacking lipid particles bears a defect in ergosterol formation. J. Biol. Chem. 279:31190-96
    • (2004) J. Biol. Chem. , vol.279 , pp. 31190-31196
    • Sorger, D.1    Athenstaedt, K.2    Hrastnik, C.3    Daum, G.4
  • 212
    • 0036135597 scopus 로고    scopus 로고
    • Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae
    • Sorger D, Daum G. 2002. Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae. J. Bacteriol. 184:519-24
    • (2002) J. Bacteriol. , vol.184 , pp. 519-524
    • Sorger, D.1    Daum, G.2
  • 213
    • 0026274977 scopus 로고
    • Chemistry and function of mammalian sebaceous lipids
    • Stewart ME, Downing DT. 1991. Chemistry and function of mammalian sebaceous lipids. Adv. Lipid Res. 24:263-301
    • (1991) Adv. Lipid Res. , vol.24 , pp. 263-301
    • Stewart, M.E.1    Downing, D.T.2
  • 216
    • 0035199747 scopus 로고    scopus 로고
    • Two novel prevalent polymorphisms in the hormone-sensitive lipase gene have no effect on insulin sensitivity of lipolysis and glucose disposal
    • Stumvoll M, Wahl HG, Jacob S, Rettig A, Machicao F, Haring H. 2001. Two novel prevalent polymorphisms in the hormone-sensitive lipase gene have no effect on insulin sensitivity of lipolysis and glucose disposal. J. Lipid Res. 42:1782-88
    • (2001) J. Lipid Res. , vol.42 , pp. 1782-1788
    • Stumvoll, M.1    Wahl, H.G.2    Jacob, S.3    Rettig, A.4    Machicao, F.5    Haring, H.6
  • 217
    • 0030859046 scopus 로고    scopus 로고
    • Molecular aspects of intracellular sterol esterification: The acyl coenzyme A:cholesterol acyltransferase reaction
    • Sturley SL. 1997. Molecular aspects of intracellular sterol esterification: the acyl coenzyme A:cholesterol acyltransferase reaction. Curr. Opin. Lipidol. 8:167-73
    • (1997) Curr. Opin. Lipidol. , vol.8 , pp. 167-173
    • Sturley, S.L.1
  • 218
    • 84864864505 scopus 로고    scopus 로고
    • Lipid droplet formation on opposing sides of the endoplasmic reticulum
    • Sturley SL, HussainMM.2012. Lipid droplet formation on opposing sides of the endoplasmic reticulum. J. Lipid Res. 53:1800-10
    • (2012) J. Lipid Res. , vol.53 , pp. 1800-1810
    • Sturley, S.L.1    Hussain, M.M.2
  • 219
    • 0031821193 scopus 로고    scopus 로고
    • Trans unsaturated fatty acids inhibit lecithin: Cholesterol acyltransferase and alter its positional specificity
    • Subbaiah PV, Subramanian VS, Liu M. 1998. Trans unsaturated fatty acids inhibit lecithin: cholesterol acyltransferase and alter its positional specificity. J. Lipid Res. 39:1438-47
    • (1998) J. Lipid Res. , vol.39 , pp. 1438-1447
    • Subbaiah, P.V.1    Subramanian, V.S.2    Liu, M.3
  • 220
    • 50549221698 scopus 로고
    • Fatty acid specificities and rates of cholesterol esterification in vivo and in vitro
    • Sugano M, Portman OW. 1964. Fatty acid specificities and rates of cholesterol esterification in vivo and in vitro. Arch. Biochem. Biophys. 107:341-51
    • (1964) Arch. Biochem. Biophys. , vol.107 , pp. 341-351
    • Sugano, M.1    Portman, O.W.2
  • 221
    • 31544451530 scopus 로고    scopus 로고
    • Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism
    • Suviolahti E, Reue K, Cantor RM, Phan J, Gentile M, et al. 2006. Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism. Hum. Mol. Genet. 15:377-86
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 377-386
    • Suviolahti, E.1    Reue, K.2    Cantor, R.M.3    Phan, J.4    Gentile, M.5
  • 222
    • 0034733732 scopus 로고    scopus 로고
    • Identification of a sequence of apolipoprotein A-I associated with the activation of lecithin:cholesterol acyltransferase
    • Sviridov D, Hoang A, Sawyer WH, Fidge NH. 2000. Identification of a sequence of apolipoprotein A-I associated with the activation of lecithin:cholesterol acyltransferase. J. Biol. Chem. 275:19707-12
    • (2000) J. Biol. Chem. , vol.275 , pp. 19707-19712
    • Sviridov, D.1    Hoang, A.2    Sawyer, W.H.3    Fidge, N.H.4
  • 223
    • 38049184643 scopus 로고    scopus 로고
    • The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology
    • Szymanski KM, Binns D, Bartz R, Grishin NV, Li WP, et al. 2007. The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology. Proc. Natl. Acad. Sci. USA 104:20890-95
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 20890-20895
    • Szymanski, K.M.1    Binns, D.2    Bartz, R.3    Grishin, N.V.4    Li, W.P.5
  • 224
    • 20144369491 scopus 로고    scopus 로고
    • Loss of lysophospholipase 3 increases atherosclerosis in apolipoprotein E-deficient mice
    • Taniyama Y, Fuse H, Satomi T, Tozawa R, Yasuhara Y, et al. 2005. Loss of lysophospholipase 3 increases atherosclerosis in apolipoprotein E-deficient mice. Biochem. Biophys. Res. Commun. 330:104-10
    • (2005) Biochem. Biophys. Res. Commun. , vol.330 , pp. 104-110
    • Taniyama, Y.1    Fuse, H.2    Satomi, T.3    Tozawa, R.4    Yasuhara, Y.5
  • 225
    • 0033515842 scopus 로고    scopus 로고
    • Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase
    • Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, et al. 1999. Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase. Biochem. Biophys. Res. Commun. 257:50-56
    • (1999) Biochem. Biophys. Res. Commun. , vol.257 , pp. 50-56
    • Taniyama, Y.1    Shibata, S.2    Kita, S.3    Horikoshi, K.4    Fuse, H.5
  • 226
    • 20844449696 scopus 로고    scopus 로고
    • Effects of the acyl coenzyme A:cholesterol acyltransferase inhibitor avasimibe on human atherosclerotic lesions
    • Tardif JC, Gregoire J, L?Allier PL, Anderson TJ, Bertrand O, et al. 2004. Effects of the acyl coenzyme A:cholesterol acyltransferase inhibitor avasimibe on human atherosclerotic lesions. Circulation 110:3372-77
    • (2004) Circulation , vol.110 , pp. 3372-3377
    • Tardif, J.C.1    Gregoire, J.2    Lallier, P.L.3    Anderson, T.J.4    Bertrand, O.5
  • 227
    • 79955958008 scopus 로고    scopus 로고
    • Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance
    • Taschler U, Radner FP, Heier C, Schreiber R, Schweiger M, et al. 2011. Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. J. Biol. Chem. 286:17467-77
    • (2011) J. Biol. Chem. , vol.286 , pp. 17467-17477
    • Taschler, U.1    Radner, F.P.2    Heier, C.3    Schreiber, R.4    Schweiger, M.5
  • 228
    • 79955629359 scopus 로고    scopus 로고
    • Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation
    • Tian Y, Bi J, Shui G, Liu Z, Xiang Y, et al. 2011. Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation. PLoS Genet. 7:e1001364
    • (2011) PLoS Genet. , vol.7
    • Tian, Y.1    Bi, J.2    Shui, G.3    Liu, Z.4    Xiang, Y.5
  • 229
    • 0023489397 scopus 로고
    • The lipid secretion of the meibomian glands
    • Tiffany JM. 1987. The lipid secretion of the meibomian glands. Adv. Lipid Res. 22:1-62
    • (1987) Adv. Lipid Res. , vol.22 , pp. 1-62
    • Tiffany, J.M.1
  • 230
    • 0029691399 scopus 로고    scopus 로고
    • Oleosin genes in maize kernels having diverse oil contents are constitutively expressed independent of oil contents. Size and shape of intracellular oil bodies are determined by the oleosins/oils ratio
    • Ting JT, Lee K, Ratnayake C, Platt KA, Balsamo RA, Huang AH. 1996. Oleosin genes in maize kernels having diverse oil contents are constitutively expressed independent of oil contents. Size and shape of intracellular oil bodies are determined by the oleosins/oils ratio. Planta 199:158-65
    • (1996) Planta , vol.199 , pp. 158-165
    • Ting, J.T.1    Lee, K.2    Ratnayake, C.3    Platt, K.A.4    Balsamo, R.A.5    Huang, A.H.6
  • 231
    • 34147158237 scopus 로고    scopus 로고
    • Regulation of triglyceridemetabolism. I. Eukaryotic neutral lipid synthesis "many ways to skin ACAT or a DGAT."
    • Turkish A, Sturley SL. 2007. Regulation of triglyceridemetabolism. I. Eukaryotic neutral lipid synthesis: "Many ways to skin ACAT or a DGAT." Am. J. Physiol. Gastrointest. Liver Physiol. 292:G953-57
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.292
    • Turkish, A.1    Sturley, S.L.2
  • 232
    • 84880669744 scopus 로고    scopus 로고
    • Esterification of long chain dialcohols by members of the human DGAT2 gene family
    • Manuscript submitted
    • Turkish AR, Brinkman M, D?Ambrosio D, Tran AD, Cromley D, et al. 2013. Esterification of long chain dialcohols by members of the human DGAT2 gene family. J. Biol. Chem. Manuscript submitted
    • (2013) J. Biol. Chem.
    • Turkish, A.R.1    Brinkman, M.2    Dambrosio, D.3    Tran, A.D.4    Cromley, D.5
  • 233
    • 17644362367 scopus 로고    scopus 로고
    • Identification of two novel human acyl-CoA wax alcohol acyltransferases: Members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily
    • Turkish AR, Henneberry AL, Cromley D, Padamsee M, Oelkers P, et al. 2005. Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily. J. Biol. Chem. 280:14755-64
    • (2005) J. Biol. Chem. , vol.280 , pp. 14755-14764
    • Turkish, A.R.1    Henneberry, A.L.2    Cromley, D.3    Padamsee, M.4    Oelkers, P.5
  • 234
    • 67650083114 scopus 로고    scopus 로고
    • The genetics of neutral lipid biosynhesis: An evolutionary perspective
    • Turkish AR, Sturley SL. 2009. The genetics of neutral lipid biosynthesis: an evolutionary perspective. Am. J. Physiol. Endocrinol. Metab. 297:E19-27
    • (2009) Am. J. Physiol. Endocrinol. Metab. , vol.297
    • Turkish, A.R.1    Sturley, S.L.2
  • 235
    • 0036182137 scopus 로고    scopus 로고
    • Lipotoxic diseases
    • Unger RH. 2002. Lipotoxic diseases. Annu. Rev. Med. 53:319-36
    • (2002) Annu. Rev. Med. , vol.53 , pp. 319-336
    • Unger, R.H.1
  • 236
    • 13444304299 scopus 로고    scopus 로고
    • Mechanism of lipid-body formation in prokaryotes: How bacteria fatten up
    • Waltermann M, Hinz A, Robenek H, Troyer D, Reichelt R, et al. 2005. Mechanism of lipid-body formation in prokaryotes: how bacteria fatten up. Mol. Microbiol. 55:750-63
    • (2005) Mol. Microbiol. , vol.55 , pp. 750-763
    • Waltermann, M.1    Hinz, A.2    Robenek, H.3    Troyer, D.4    Reichelt, R.5
  • 237
    • 33846477310 scopus 로고    scopus 로고
    • Key enzymes for biosynthesis of neutral lipid storage compounds in prokaryotes: Properties, function and occurrence of wax ester synthases/acyl-CoA: Diacylglycerol acyltransferases
    • Waltermann M, Stoveken T, Steinbuchel A. 2007. Key enzymes for biosynthesis of neutral lipid storage compounds in prokaryotes: properties, function and occurrence of wax ester synthases/acyl-CoA: diacylglycerol acyltransferases. Biochimie 89:230-42
    • (2007) Biochimie , vol.89 , pp. 230-242
    • Waltermann, M.1    Stoveken, T.2    Steinbuchel, A.3
  • 239
    • 0027467140 scopus 로고
    • Bile salt-activated lipase. A multiple function lipolytic enzyme
    • Wang CS, Hartsuck JA. 1993. Bile salt-activated lipase. A multiple function lipolytic enzyme. Biochim. Biophys. Acta 1166:1-19
    • (1993) Biochim. Biophys. Acta , vol.1166 , pp. 1-19
    • Wang, C.S.1    Hartsuck, J.A.2
  • 241
    • 84862778000 scopus 로고    scopus 로고
    • Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids
    • Wang W, Lv N, Zhang S, Shui G, Qian H, et al. 2012. Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids. Nat. Med. 18:235-43
    • (2012) Nat. Med. , vol.18 , pp. 235-243
    • Wang, W.1    Lv, N.2    Zhang, S.3    Shui, G.4    Qian, H.5
  • 242
    • 0024819307 scopus 로고
    • Tissue-specific expression, developmental regulation, and chromosomal mapping of the lecithin: Cholesterol acyltransferase gene. Evidence for expression in brain and testes as well as liver
    • Warden CH, Langner CA, Gordon JI, Taylor BA, McLean JW, Lusis AJ. 1989. Tissue-specific expression, developmental regulation, and chromosomal mapping of the lecithin: cholesterol acyltransferase gene. Evidence for expression in brain and testes as well as liver. J. Biol. Chem. 264:21573-81
    • (1989) J. Biol. Chem. , vol.264 , pp. 21573-21581
    • Warden, C.H.1    Langner, C.A.2    Gordon, J.I.3    Taylor, B.A.4    McLean, J.W.5    Lusis, A.J.6
  • 243
    • 77954944275 scopus 로고    scopus 로고
    • Triacylglycerol lipases and metabolic control: Implications for health and disease
    • Watt MJ, Spriet LL. 2010. Triacylglycerol lipases and metabolic control: implications for health and disease. Am. J. Physiol. Endocrinol. Metab. 299:E162-68
    • (2010) Am. J. Physiol. Endocrinol. Metab. , vol.299
    • Watt, M.J.1    Spriet, L.L.2
  • 244
    • 79951707329 scopus 로고    scopus 로고
    • RonM. 2011. Invited review: Quantitative trait nucleotide determination in the era of genomic selection
    • Weller JI, RonM. 2011. Invited review: quantitative trait nucleotide determination in the era of genomic selection. J. Dairy Sci. 94:1082-90
    • J. Dairy Sci. , vol.94 , pp. 1082-1090
    • Weller, J.I.1
  • 245
    • 22744434906 scopus 로고    scopus 로고
    • Regulation of lipid-droplet transport by the perilipin homolog LSD2
    • Welte MA, Cermelli S, Griner J, Viera A, Guo Y, et al. 2005. Regulation of lipid-droplet transport by the perilipin homolog LSD2. Curr. Biol. 15:1266-75
    • (2005) Curr. Biol. , vol.15 , pp. 1266-1275
    • Welte, M.A.1    Cermelli, S.2    Griner, J.3    Viera, A.4    Guo, Y.5
  • 246
    • 0037247566 scopus 로고    scopus 로고
    • Palmitoleic acid isomer (C16:1delta6) in human skin sebum is effective against gram-positive bacteria
    • Wille JJ, Kydonieus A. 2003. Palmitoleic acid isomer (C16:1delta6) in human skin sebum is effective against gram-positive bacteria. Skin Pharmacol. Appl. Skin Physiol. 16:176-87
    • (2003) Skin Pharmacol. Appl. Skin Physiol. , vol.16 , pp. 176-187
    • Wille, J.J.1    Kydonieus, A.2
  • 247
    • 0037417922 scopus 로고    scopus 로고
    • Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice
    • Willner EL, Tow B, Buhman KK, Wilson M, Sanan DA, et al. 2003. Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice. Proc. Natl. Acad. Sci. USA 100:1262-67
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1262-1267
    • Willner, E.L.1    Tow, B.2    Buhman, K.K.3    Wilson, M.4    Sanan, D.A.5
  • 249
    • 0043268763 scopus 로고    scopus 로고
    • Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase
    • Winzell MS, Svensson H, Enerback S, Ravnskjaer K, Mandrup S, et al. 2003. Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase. Diabetes 52:2057-65
    • (2003) Diabetes , vol.52 , pp. 2057-2065
    • Winzell, M.S.1    Svensson, H.2    Enerback, S.3    Ravnskjaer, K.4    Mandrup, S.5
  • 251
    • 33845517481 scopus 로고    scopus 로고
    • OXPAT/PAT-1 is a PPARinduced lipid droplet protein that promotes fatty acid utilization
    • Wolins NE, Quaynor BK, Skinner J.R., Tzekov A, Croce MA, et al. 2006. OXPAT/PAT-1 is a PPARinduced lipid droplet protein that promotes fatty acid utilization. Diabetes 55:3418-28
    • (2006) Diabetes , vol.55 , pp. 3418-3428
    • Wolins, N.E.1    Quaynor, B.K.2    Skinner, J.R.3    Tzekov, A.4    Croce, M.A.5
  • 252
  • 254
    • 0033769564 scopus 로고    scopus 로고
    • Proteomics reveal a link between the endoplasmic reticulum and lipid secretory mechanisms in mammary epithelial cells
    • Wu CC, Howell KE, Neville MC, Yates J.R., McManaman JL. 2000. Proteomics reveal a link between the endoplasmic reticulum and lipid secretory mechanisms in mammary epithelial cells. Electrophoresis 21:3470-82
    • (2000) Electrophoresis , vol.21 , pp. 3470-3482
    • Wu, C.C.1    Howell, K.E.2    Neville, M.C.3    Yates, J.R.4    McManaman, J.L.5
  • 255
    • 78649770264 scopus 로고    scopus 로고
    • Polymorphism of rs1044925 in the acyl-CoA:cholesterol acyltransferase-1 gene and serum lipid levels in the Guangxi Bai Ku Yao and Han populations
    • Wu DF, Yin RX, Aung LH, Hu XJ, Cao XL, et al. 2010. Polymorphism of rs1044925 in the acyl-CoA:cholesterol acyltransferase-1 gene and serum lipid levels in the Guangxi Bai Ku Yao and Han populations. Lipids Health Dis. 9:139
    • (2010) Lipids Health Dis. , vol.9 , pp. 139
    • Wu, D.F.1    Yin, R.X.2    Aung, L.H.3    Hu, X.J.4    Cao, X.L.5
  • 256
    • 84855743854 scopus 로고    scopus 로고
    • Sex-specific association of ACAT-1 rs1044925 SNP and serum lipid levels in the hypercholesterolemic subjects
    • Wu DF, Yin RX, Aung LH, Li Q, Yan TT, et al. 2012. Sex-specific association of ACAT-1 rs1044925 SNP and serum lipid levels in the hypercholesterolemic subjects. Lipids Health Dis. 11:9
    • (2012) Lipids Health Dis. , vol.11 , pp. 9
    • Wu, D.F.1    Yin, R.X.2    Aung, L.H.3    Li, Q.4    Yan, T.T.5
  • 257
    • 80054678271 scopus 로고    scopus 로고
    • Evidence that diacylglycerol acyltransferase 1 (DGAT1) has dual membrane topology in the endoplasmic reticulum of HepG2 cells
    • Wurie HR, Buckett L, Zammit VA. 2011. Evidence that diacylglycerol acyltransferase 1 (DGAT1) has dual membrane topology in the endoplasmic reticulum of HepG2 cells. J. Biol. Chem. 286:36238-47
    • (2011) J. Biol. Chem. , vol.286 , pp. 36238-36247
    • Wurie, H.R.1    Buckett, L.2    Zammit, V.A.3
  • 259
    • 0034647531 scopus 로고    scopus 로고
    • Absence ofACAT-1attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia
    • YagyuH, Kitamine T, Osuga J, TozawaR, ChenZ, et al. 2000. Absence ofACAT-1attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia. J. Biol. Chem. 275:21324-30
    • (2000) J. Biol. Chem. , vol.275 , pp. 21324-21330
    • Yagyu, H.1    Kitamine, T.2    Osuga, J.3    Tozawa, R.4    Chen, Z.5
  • 260
    • 34250356015 scopus 로고    scopus 로고
    • Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis
    • Yamaguchi K, Yang L, McCall S, Huang J, Yu XX, et al. 2007. Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. Hepatology 45:1366-74
    • (2007) Hepatology , vol.45 , pp. 1366-1374
    • Yamaguchi, K.1    Yang, L.2    McCall, S.3    Huang, J.4    Yu, X.X.5
  • 262
    • 0031041071 scopus 로고    scopus 로고
    • Functional expression of a cDNA to human acyl-coenzyme A:cholesterol acyltransferase in yeast. Species-dependent substrate specificity and inhibitor sensitivity
    • Yang H, Cromley D, Wang H, Billheimer JT, Sturley SL. 1997. Functional expression of a cDNA to human acyl-coenzyme A:cholesterol acyltransferase in yeast. Species-dependent substrate specificity and inhibitor sensitivity. J. Biol. Chem. 272:3980-85
    • (1997) J. Biol. Chem. , vol.272 , pp. 3980-3985
    • Yang, H.1    Cromley, D.2    Wang, H.3    Billheimer, J.T.4    Sturley, S.L.5
  • 263
    • 77249118270 scopus 로고    scopus 로고
    • The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase
    • Yang X, Lu X, Lombes M, Rha GB, Chi YI, et al. 2010. The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase. Cell Metab. 11:194-205
    • (2010) Cell Metab. , vol.11 , pp. 194-205
    • Yang, X.1    Lu, X.2    Lombes, M.3    Rha, G.B.4    Chi, Y.I.5
  • 264
    • 58749098423 scopus 로고    scopus 로고
    • Cideb, an ER-and lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B
    • Ye J, Li JZ, Liu Y, Li X, Yang T, et al. 2009. Cideb, an ER-and lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B. Cell Metab. 9:177-90
    • (2009) Cell Metab. , vol.9 , pp. 177-190
    • Ye, J.1    Li, J.Z.2    Liu, Y.3    Li, X.4    Yang, T.5
  • 265
    • 84863115587 scopus 로고    scopus 로고
    • Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of acyl-CoA:diacylglycerol acyltransferase
    • Yeh VS, Beno DW, Brodjian S, Brune ME, Cullen SC, et al. 2012. Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of acyl-CoA:diacylglycerol acyltransferase J. Med. Chem. 55 1751-57
    • (2012) J. Med. Chem. , vol.55 , pp. 1751-1757
    • Yeh, V.S.1    Beno, D.W.2    Brodjian, S.3    Brune, M.E.4    Cullen, S.C.5
  • 266
    • 27544437517 scopus 로고    scopus 로고
    • Ahuman skin multifunctionalO-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl esters
    • YenCL, BrownCH4th, Monetti M, FareseRVJr. 2005.Ahuman skin multifunctionalO-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl esters. J. Lipid Res. 46:2388-97
    • (2005) J. Lipid Res. , vol.46 , pp. 2388-2397
    • Yen, C.L.1    Brown, C.H.2    Monetti, M.3    Farese Jr., R.V.4
  • 267
    • 64149083743 scopus 로고    scopus 로고
    • Deficiency of the intestinal enzyme acylCoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding
    • Yen CL, Cheong ML, Grueter C, Zhou P, Moriwaki J, et al. 2009. Deficiency of the intestinal enzyme acylCoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding. Nat. Med. 15:442-46
    • (2009) Nat. Med. , vol.15 , pp. 442-446
    • Yen, C.L.1    Cheong, M.L.2    Grueter, C.3    Zhou, P.4    Moriwaki, J.5
  • 268
    • 0037790713 scopus 로고    scopus 로고
    • MGAT2, a monoacylglycerol acyltransferase expressed in the small intestine
    • Yen CL, Farese Jr. R.V. 2003. MGAT2, a monoacylglycerol acyltransferase expressed in the small intestine. J. Biol. Chem. 278:18532-37
    • (2003) J. Biol. Chem. , vol.278 , pp. 18532-18537
    • Yen, C.L.1    Farese Jr., R.V.2
  • 269
    • 24744443740 scopus 로고    scopus 로고
    • The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters
    • Yen CL, Monetti M, Burri BJ, Farese Jr. R.V. 2005. The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters. J. Lipid Res. 46:1502-11
    • (2005) J. Lipid Res. , vol.46 , pp. 1502-1511
    • Yen, C.L.1    Monetti, M.2    Burri, B.J.3    Farese Jr., R.V.4
  • 271
    • 58149457426 scopus 로고    scopus 로고
    • Thematic review series: Glycerolipids. DGAT enzymes and triacylglycerol biosynthesis
    • Yen CL, Stone SJ, Koliwad S, Harris C, Farese Jr. R.V. 2008. Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis. J. Lipid Res. 49:2283-301
    • (2008) J. Lipid Res. , vol.49 , pp. 2283-2301
    • Yen, C.L.1    Stone, S.J.2    Koliwad, S.3    Harris, C.4    Farese Jr., R.V.5
  • 272
    • 78650124326 scopus 로고    scopus 로고
    • Which CIDE are you on? Apoptosis and energy metabolism
    • Yonezawa T, Kurata R, Kimura M, Inoko H. 2011. Which CIDE are you on? Apoptosis and energy metabolism. Mol. Biosyst. 7:91-100
    • (2011) Mol. Biosyst. , vol.7 , pp. 91-100
    • Yonezawa, T.1    Kurata, R.2    Kimura, M.3    Inoko, H.4
  • 273
    • 23044450772 scopus 로고    scopus 로고
    • Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice
    • Yu XX, Murray SF, Pandey SK, Booten SL, Bao D, et al. 2005. Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice. Hepatology 42:362-71
    • (2005) Hepatology , vol.42 , pp. 362-371
    • Yu, X.X.1    Murray, S.F.2    Pandey, S.K.3    Booten, S.L.4    Bao, D.5
  • 274
    • 80053909233 scopus 로고    scopus 로고
    • Proteome of skeletal muscle lipid droplet reveals association with mitochondria and apolipoprotein a-I
    • Zhang H, Wang Y, Li J, Yu J, Pu J, et al. 2011. Proteome of skeletal muscle lipid droplet reveals association with mitochondria and apolipoprotein a-I. J. Proteome Res. 10:4757-68
    • (2011) J. Proteome Res. , vol.10 , pp. 4757-4768
    • Zhang, H.1    Wang, Y.2    Li, J.3    Yu, J.4    Pu, J.5
  • 275
    • 84861453470 scopus 로고    scopus 로고
    • Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood
    • Zhang J, Kelley KL, Marshall SM, Davis MA, Wilson MD, et al. 2012. Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood. J. Lipid Res. 53:1144-52
    • (2012) J. Lipid Res. , vol.53 , pp. 1144-1152
    • Zhang, J.1    Kelley, K.L.2    Marshall, S.M.3    Davis, M.A.4    Wilson, M.D.5
  • 276
    • 75649133901 scopus 로고    scopus 로고
    • DGAT1 and PDAT1 acyltransferases have overlapping functions in Arabidopsis triacylglycerol biosynthesis and are essential for normal pollen and seed development
    • Zhang M, Fan J, Taylor DC, Ohlrogge JB. 2009. DGAT1 and PDAT1 acyltransferases have overlapping functions in Arabidopsis triacylglycerol biosynthesis and are essential for normal pollen and seed development. Plant Cell 21:3885-901
    • (2009) Plant Cell , vol.21 , pp. 3885-3901
    • Zhang, M.1    Fan, J.2    Taylor, D.C.3    Ohlrogge, J.B.4
  • 277
    • 77949524057 scopus 로고    scopus 로고
    • Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans
    • Zhang SO, Box AC, Xu N, Le Men J, Yu J, et al. 2010. Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 107:4640-45
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 4640-4645
    • Zhang, S.O.1    Box, A.C.2    Xu, N.3    Le Men, J.4    Yu, J.5
  • 278
    • 39149122218 scopus 로고    scopus 로고
    • Validation of diacyl glycerolacyltransferase i as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor
    • Zhao G, Souers AJ, Voorbach M, Falls HD, Droz B, et al. 2008. Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor. J. Med. Chem. 51:380-83
    • (2008) J. Med. Chem. , vol.51 , pp. 380-383
    • Zhao, G.1    Souers, A.J.2    Voorbach, M.3    Falls, H.D.4    Droz, B.5
  • 280
    • 0033974053 scopus 로고    scopus 로고
    • Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae
    • Zweytick D, Leitner E, Kohlwein SD, Yu C, Rothblatt J, Daum G. 2000. Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae. Eur. J. Biochem. 267:1075-82
    • (2000) Eur. J. Biochem. , vol.267 , pp. 1075-1082
    • Zweytick, D.1    Leitner, E.2    Kohlwein, S.D.3    Yu, C.4    Rothblatt, J.5    Daum, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.