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Volumn 55, Issue 12, 2006, Pages 3418-3428

OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOPHILIN; FAT DROPLET; INSULIN; LONG CHAIN FATTY ACID; MEMBRANE PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PROTEIN OXPAT; TRIACYLGLYCEROL;

EID: 33845517481     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-0399     Document Type: Article
Times cited : (266)

References (56)
  • 1
    • 0037200026 scopus 로고    scopus 로고
    • Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium
    • Miura S, Gan JW, Brzostowski J, Parisi MJ, Schultz CJ, Londos C, Oliver B, Kimmel AR: Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium. J Biol Chem 277:32253-32257, 2002
    • (2002) J Biol Chem , vol.277 , pp. 32253-32257
    • Miura, S.1    Gan, J.W.2    Brzostowski, J.3    Parisi, M.J.4    Schultz, C.J.5    Londos, C.6    Oliver, B.7    Kimmel, A.R.8
  • 2
    • 9444250464 scopus 로고    scopus 로고
    • The central role of perilipin a in lipid metabolism and adipocyte lipolysis
    • Tansey JT, Sztalryd C, Hlavin EM, Kimmel AR, Londos C: The central role of perilipin a in lipid metabolism and adipocyte lipolysis. IUBMB Life 56:379-385, 2004
    • (2004) IUBMB Life , vol.56 , pp. 379-385
    • Tansey, J.T.1    Sztalryd, C.2    Hlavin, E.M.3    Kimmel, A.R.4    Londos, C.5
  • 4
    • 0034623950 scopus 로고    scopus 로고
    • Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysis
    • Brasaemle DL, Rubin B, Harten IA, Gruia-Gray J, Kimmel AR, Londos C: Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysis. J Biol Chem 275:38486-38493, 2000
    • (2000) J Biol Chem , vol.275 , pp. 38486-38493
    • Brasaemle, D.L.1    Rubin, B.2    Harten, I.A.3    Gruia-Gray, J.4    Kimmel, A.R.5    Londos, C.6
  • 5
    • 0037477829 scopus 로고    scopus 로고
    • Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation
    • Sztalryd C, Xu G, Dorward H, Tansey JT, Contreras JA, Kimmel AR, Londos C: Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation. J Cell Biol 161:1093-1103, 2003
    • (2003) J Cell Biol , vol.161 , pp. 1093-1103
    • Sztalryd, C.1    Xu, G.2    Dorward, H.3    Tansey, J.T.4    Contreras, J.A.5    Kimmel, A.R.6    Londos, C.7
  • 6
    • 31344437783 scopus 로고    scopus 로고
    • Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein
    • Chang BH, Li L, Paul A, Taniguchi S, Nannegari V, Heird WC, Chan L: Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein. Mol Cell Biol 26:1063-1076, 2006
    • (2006) Mol Cell Biol , vol.26 , pp. 1063-1076
    • Chang, B.H.1    Li, L.2    Paul, A.3    Taniguchi, S.4    Nannegari, V.5    Heird, W.C.6    Chan, L.7
  • 11
    • 0030724392 scopus 로고    scopus 로고
    • Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein
    • Brasaemle DL, Barber T, Wolins NE, Serrero G, Blanchette-Mackie EJ, Londos C: Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein. J Lipid Res 38:2249-2263, 1997
    • (1997) J Lipid Res , vol.38 , pp. 2249-2263
    • Brasaemle, D.L.1    Barber, T.2    Wolins, N.E.3    Serrero, G.4    Blanchette-Mackie, E.J.5    Londos, C.6
  • 12
    • 0025772167 scopus 로고
    • Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets
    • Greenberg AS, Egan JJ, Wek SA, Garty NB, Blanchette-Mackie EJ, Londos C: Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets. J Biol Chem 266:11341-11346, 1991
    • (1991) J Biol Chem , vol.266 , pp. 11341-11346
    • Greenberg, A.S.1    Egan, J.J.2    Wek, S.A.3    Garty, N.B.4    Blanchette-Mackie, E.J.5    Londos, C.6
  • 13
    • 0027145164 scopus 로고
    • Isolation of cDNAs for perilipins a and B: Sequence and expression of lipid droplet-associated proteins of adipocytes
    • Greenberg AS, Egan JJ, Wek SA, Moos MC Jr, Londos C, Kimmel AR: Isolation of cDNAs for perilipins A and B: sequence and expression of lipid droplet-associated proteins of adipocytes. Proc Natl Acad Sci U S A 90:12035-12039, 1993
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 12035-12039
    • Greenberg, A.S.1    Egan, J.J.2    Wek, S.A.3    Moos Jr., M.C.4    Londos, C.5    Kimmel, A.R.6
  • 14
    • 0030903768 scopus 로고    scopus 로고
    • Post-translational regulation of perilipin expression: Stabilization by stored intracellular neutral lipids
    • Brasaemle DL, Barber T, Kimmel AR, Londos C: Post-translational regulation of perilipin expression: stabilization by stored intracellular neutral lipids. J Biol Chem 272:9378-9387, 1997
    • (1997) J Biol Chem , vol.272 , pp. 9378-9387
    • Brasaemle, D.L.1    Barber, T.2    Kimmel, A.R.3    Londos, C.4
  • 15
    • 0032076636 scopus 로고    scopus 로고
    • TIP47: A cargo selection device for mannose 6-phosphate receptor trafficking
    • Diaz E, Pfeffer SR: TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking. Cell 93:433-443, 1998
    • (1998) Cell , vol.93 , pp. 433-443
    • Diaz, E.1    Pfeffer, S.R.2
  • 16
    • 30044445455 scopus 로고    scopus 로고
    • Post-translational regulation of adipose differentiation-related protein by the ubiquitin/proteasome pathway
    • Xu G, Sztalryd C, Lu X, Tansey JT, Gan J, Dorward H, Kimmel AR, Londos C: Post-translational regulation of adipose differentiation-related protein by the ubiquitin/proteasome pathway. J Biol Chem 280:42841-42847, 2005
    • (2005) J Biol Chem , vol.280 , pp. 42841-42847
    • Xu, G.1    Sztalryd, C.2    Lu, X.3    Tansey, J.T.4    Gan, J.5    Dorward, H.6    Kimmel, A.R.7    Londos, C.8
  • 17
    • 33646017106 scopus 로고    scopus 로고
    • Degradation of perilipin is mediated through ubiquitination-proteasome pathway
    • Xu G, Sztalryd C, Londos C: Degradation of perilipin is mediated through ubiquitination-proteasome pathway. Biochim Biophys Acta 1761:83-90, 2006
    • (2006) Biochim Biophys Acta , vol.1761 , pp. 83-90
    • Xu, G.1    Sztalryd, C.2    Londos, C.3
  • 20
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee SS, Pineau T, Drago J, Lee EJ, Owens JW, Kroetz DL, Fernandez-Salguero PM, Westphal H, Gonzalez FJ: Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol 15:3012-3022, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 3012-3022
    • Lee, S.S.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, F.J.9
  • 22
    • 0033594980 scopus 로고    scopus 로고
    • A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: The PPARalpha-null mouse as a model of fatty acid oxidation disorders
    • Leone TC, Weinheimer CJ, Kelly DP: A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci U S A 96:7473-7478, 1999
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7473-7478
    • Leone, T.C.1    Weinheimer, C.J.2    Kelly, D.P.3
  • 23
    • 0024837626 scopus 로고
    • The tissue-specific expression and developmental regulation of two nuclear genes encoding rat mitochondrial proteins: Medium chain acyl-CoA dehydrogenase and mitochondrial malate dehydrogenase
    • Kelly DP, Gordon JI, Alpers R, Strauss AW: The tissue-specific expression and developmental regulation of two nuclear genes encoding rat mitochondrial proteins: medium chain acyl-CoA dehydrogenase and mitochondrial malate dehydrogenase. J Biol Chem 264:18921-18925, 1989
    • (1989) J Biol Chem , vol.264 , pp. 18921-18925
    • Kelly, D.P.1    Gordon, J.I.2    Alpers, R.3    Strauss, A.W.4
  • 24
    • 8744267532 scopus 로고    scopus 로고
    • Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes
    • Brasaemle DL, Dolios G, Shapiro L, Wang R: Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes. J Biol Chem 279:46835-46842, 2004
    • (2004) J Biol Chem , vol.279 , pp. 46835-46842
    • Brasaemle, D.L.1    Dolios, G.2    Shapiro, L.3    Wang, R.4
  • 25
    • 33244483352 scopus 로고    scopus 로고
    • OP9 mouse stromal cells rapidly differentiate into adipocytes: Characterization of a useful new model of adipogenesis
    • Wolins NE, Quaynor BK, Skinner JR, Tzekov A, Park C, Choi K, Bickel PE: OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis. J Lipid Res 47:450-460, 2006
    • (2006) J Lipid Res , vol.47 , pp. 450-460
    • Wolins, N.E.1    Quaynor, B.K.2    Skinner, J.R.3    Tzekov, A.4    Park, C.5    Choi, K.6    Bickel, P.E.7
  • 26
    • 0029862497 scopus 로고    scopus 로고
    • A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes
    • Ory DS, Neugeboren BA, Mulligan RC: A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc Natl Acad Sci U S A 93:11400-11406, 1996
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11400-11406
    • Ory, D.S.1    Neugeboren, B.A.2    Mulligan, R.C.3
  • 28
    • 0037332279 scopus 로고    scopus 로고
    • Characterization of fatty acid oxidation in human muscle mitochondria and myoblasts
    • Djouadi F, Bonnefont JP, Munnich A, Bastin J: Characterization of fatty acid oxidation in human muscle mitochondria and myoblasts. Mol Genet Metab 78:112-118, 2003
    • (2003) Mol Genet Metab , vol.78 , pp. 112-118
    • Djouadi, F.1    Bonnefont, J.P.2    Munnich, A.3    Bastin, J.4
  • 30
    • 0023120630 scopus 로고
    • Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp
    • Bergman RN, Prager R, Volund A, Olefsky JM: Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp. J Clin Invest 79:790-800, 1987
    • (1987) J Clin Invest , vol.79 , pp. 790-800
    • Bergman, R.N.1    Prager, R.2    Volund, A.3    Olefsky, J.M.4
  • 31
    • 0347624611 scopus 로고    scopus 로고
    • MINIMOD Millennium: A computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test
    • Boston RC, Stefanovski D, Moate PJ, Sumner AE, Watanabe RM, Bergman RN: MINIMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test. Diabetes Techno Ther 5:1003-1015, 2003
    • (2003) Diabetes Techno Ther , vol.5 , pp. 1003-1015
    • Boston, R.C.1    Stefanovski, D.2    Moate, P.J.3    Sumner, A.E.4    Watanabe, R.M.5    Bergman, R.N.6
  • 32
    • 23644446750 scopus 로고    scopus 로고
    • Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: Association with cytokine expression, insulin resistance, and reduction by pioglitazone
    • Di Gregorio GB, Yao-Borengasser A, Rasouli N, Varma V, Lu T, Miles LM, Ranganathan G, Peterson CA, McGehee RE, Kern PA: Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone. Diabetes 54:2305-2313, 2005
    • (2005) Diabetes , vol.54 , pp. 2305-2313
    • Di Gregorio, G.B.1    Yao-Borengasser, A.2    Rasouli, N.3    Varma, V.4    Lu, T.5    Miles, L.M.6    Ranganathan, G.7    Peterson, C.A.8    McGehee, R.E.9    Kern, P.A.10
  • 33
    • 16244398103 scopus 로고    scopus 로고
    • Mimicking cellular sorting improves prediction of subcellular localization
    • Nair R, Rost B: Mimicking cellular sorting improves prediction of subcellular localization. J Mol Biol 348:85-100, 2005
    • (2005) J Mol Biol , vol.348 , pp. 85-100
    • Nair, R.1    Rost, B.2
  • 36
    • 2342466747 scopus 로고    scopus 로고
    • Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-γ
    • Dalen KT, Schoonjans K, Ulven SM, Weedon-Fekjaer MS, Bentzen TG, Koutnikova H, Auwerx J, Nebb HI: Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-γ. Diabetes 53:1243-1252, 2004
    • (2004) Diabetes , vol.53 , pp. 1243-1252
    • Dalen, K.T.1    Schoonjans, K.2    Ulven, S.M.3    Weedon-Fekjaer, M.S.4    Bentzen, T.G.5    Koutnikova, H.6    Auwerx, J.7    Nebb, H.I.8
  • 37
    • 33845533956 scopus 로고    scopus 로고
    • Decrease in intramuscular lipid droplets and translocation of hormone-sensitive lipase in response to muscle contraction and epinephrine
    • In press
    • Prats C, Donsmark M, Qvortrup K, Londos C, Sztalryd C, Holm C, Galbo H, Ploug T: Decrease in intramuscular lipid droplets and translocation of hormone-sensitive lipase in response to muscle contraction and epinephrine. J Lipid Res. In press
    • J Lipid Res
    • Prats, C.1    Donsmark, M.2    Qvortrup, K.3    Londos, C.4    Sztalryd, C.5    Holm, C.6    Galbo, H.7    Ploug, T.8
  • 40
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • Desvergne B, Wahli W: Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 20:649-688, 1999
    • (1999) Endocr Rev , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 41
    • 2042437052 scopus 로고    scopus 로고
    • Identification of a functional peroxisome proliferator-activated receptor responsive element within the murine perilipin gene
    • Nagai S, Shimizu C, Umetsu M, Taniguchi S, Endo M, Miyoshi H, Yoshioka N, Kubo M, Koike T: Identification of a functional peroxisome proliferator- activated receptor responsive element within the murine perilipin gene. Endocrinology 145:2346-2356, 2004
    • (2004) Endocrinology , vol.145 , pp. 2346-2356
    • Nagai, S.1    Shimizu, C.2    Umetsu, M.3    Taniguchi, S.4    Endo, M.5    Miyoshi, H.6    Yoshioka, N.7    Kubo, M.8    Koike, T.9
  • 42
    • 1642458359 scopus 로고    scopus 로고
    • Tissue-selective, bidirectional regulation of PEX11 alpha and perilipin genes through a common peroxisome proliferator response element
    • Shimizu M, Takeshita A, Tsukamoto T, Gonzalez FJ, Osumi T: Tissue-selective, bidirectional regulation of PEX11 alpha and perilipin genes through a common peroxisome proliferator response element. Mol Cell Biol 24:1313-1323, 2004
    • (2004) Mol Cell Biol , vol.24 , pp. 1313-1323
    • Shimizu, M.1    Takeshita, A.2    Tsukamoto, T.3    Gonzalez, F.J.4    Osumi, T.5
  • 43
    • 1642378571 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor gamma regulates expression of the perilipin gene in adipocytes
    • Arimura N, Horiba T, Imagawa M, Shimizu M, Sato R: The peroxisome proliferator-activated receptor gamma regulates expression of the perilipin gene in adipocytes. J Biol Chem 279:10070-10076, 2004
    • (2004) J Biol Chem , vol.279 , pp. 10070-10076
    • Arimura, N.1    Horiba, T.2    Imagawa, M.3    Shimizu, M.4    Sato, R.5
  • 44
    • 33645526855 scopus 로고    scopus 로고
    • Regulation of ADRP expression by long-chain polyunsaturated fatty acids in BeWo cells, a human placental choriocarcinoma cell line
    • Tobin KA, Harsem NK, Dalen KT, Staff AC, Nebb HI, Duttaroy AK: Regulation of ADRP expression by long-chain polyunsaturated fatty acids in BeWo cells, a human placental choriocarcinoma cell line. J Lipid Res 47:815-823, 2006
    • (2006) J Lipid Res , vol.47 , pp. 815-823
    • Tobin, K.A.1    Harsem, N.K.2    Dalen, K.T.3    Staff, A.C.4    Nebb, H.I.5    Duttaroy, A.K.6
  • 45
    • 33646863002 scopus 로고    scopus 로고
    • PPARalpha activators and fasting induce the expression of adipose differentiation-related protein in liver
    • Dalen KT, Ulven SM, Arntsen BM, Solaas K, Nebb HI: PPARalpha activators and fasting induce the expression of adipose differentiation-related protein in liver. J Lipid Res 47:931-943, 2006
    • (2006) J Lipid Res , vol.47 , pp. 931-943
    • Dalen, K.T.1    Ulven, S.M.2    Arntsen, B.M.3    Solaas, K.4    Nebb, H.I.5
  • 46
    • 0032553545 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes
    • Kroetz DL, Yook P, Costet P, Bianchi P, Pineau T: Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes. J Biol Chem 273:31581-31589, 1998
    • (1998) J Biol Chem , vol.273 , pp. 31581-31589
    • Kroetz, D.L.1    Yook, P.2    Costet, P.3    Bianchi, P.4    Pineau, T.5
  • 47
    • 0031898610 scopus 로고    scopus 로고
    • PPAR-γ: Adipogenic regulator and thiazolidinedione receptor
    • Spiegelman BM: PPAR-γ: adipogenic regulator and thiazolidinedione receptor. Diabetes 47:507-514, 1998
    • (1998) Diabetes , vol.47 , pp. 507-514
    • Spiegelman, B.M.1
  • 48
    • 28744448555 scopus 로고    scopus 로고
    • Structural and functional consequences of mitochondrial biogenesis in human adipocytes in vitro
    • Bogacka I, Ukropcova B, McNeil M, Gimble JM, Smith SR: Structural and functional consequences of mitochondrial biogenesis in human adipocytes in vitro. J Clin Endocrinol Metab 90:6650-6656, 2005
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 6650-6656
    • Bogacka, I.1    Ukropcova, B.2    McNeil, M.3    Gimble, J.M.4    Smith, S.R.5
  • 49
    • 17844385363 scopus 로고    scopus 로고
    • Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo
    • Bogacka I, Xie H, Bray GA, Smith SR: Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo. Diabetes 54:1392-1399, 2005
    • (2005) Diabetes , vol.54 , pp. 1392-1399
    • Bogacka, I.1    Xie, H.2    Bray, G.A.3    Smith, S.R.4
  • 51
    • 32644460092 scopus 로고    scopus 로고
    • From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
    • Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W: From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog Lipid Res 45:120-159, 2006
    • (2006) Prog Lipid Res , vol.45 , pp. 120-159
    • Feige, J.N.1    Gelman, L.2    Michalik, L.3    Desvergne, B.4    Wahli, W.5
  • 54
    • 33744913055 scopus 로고    scopus 로고
    • MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha
    • Yamaguchi T, Matsushita S, Motojima K, Hirose F, Osumi T: MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha. J Biol Chem 281:14232-14240, 2006
    • (2006) J Biol Chem , vol.281 , pp. 14232-14240
    • Yamaguchi, T.1    Matsushita, S.2    Motojima, K.3    Hirose, F.4    Osumi, T.5
  • 55
    • 0034076660 scopus 로고    scopus 로고
    • Fuel selection in human skeletal muscle in insulin resistance: A reexamination
    • Kelley DE, Mandarino LJ: Fuel selection in human skeletal muscle in insulin resistance: a reexamination. Diabetes 49:677-683, 2000
    • (2000) Diabetes , vol.49 , pp. 677-683
    • Kelley, D.E.1    Mandarino, L.J.2
  • 56
    • 0033927667 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance
    • Shulman GI: Cellular mechanisms of insulin resistance. J Clin Invest 106:171-176, 2000
    • (2000) J Clin Invest , vol.106 , pp. 171-176
    • Shulman, G.I.1


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