Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 3, 2003, Pages 1262-1267

  Willner, Emily L ^a   Tow, Bryan ^a   Buhman, Kimberly K ^a,e   Wilson, Martha ^c   Sanan, David A ^a   Rudel, Lawrence L ^b   Farese Jr , Robert V ^a,c,d  

^a GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COA CHOLESTERYL ACETYLTRANSFERASE 2; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; LIPOPROTEIN; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL ESTERIFICATION; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME DEFICIENCY; FEMALE; GALLSTONE FORMATION; LIPOPROTEIN BLOOD LEVEL; LIPOPROTEIN DEFICIENCY; LIVER METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SMALL INTESTINE; STRAIN DIFFERENCE;

ANIMALS; APOLIPOPROTEINS E; ARTERIOSCLEROSIS; CHOLESTEROL ESTERS; CHOLESTEROL, HDL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GENOTYPE; IMMUNOBLOTTING; LIPIDS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; PLASMIDS; STEROL O-ACYLTRANSFERASE; TRIGLYCERIDES;

ANIMALIA;

EID: 0037417922     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0336398100     Document Type: Article

References (40)

1. Chang, T. Y., Chang, C. C. Y. & Cheng, D. (1997) Annu. Rev. Biochem. 66, 613-638.
2. Buhman, K. F., Accad, M. & Farese, R. V., Jr. (2000) Biochim. Biophys. Acta 1529, 142-154.
3. Rudel, L. L., Lee, R. G. & Cockman, T. L. (2001) Curr. Opin. Lipidol. 12, 121-127.
4. Chang, C. C. Y., Huh, H. Y., Cadigan, K. M. & Chang, T. Y. (1993) J. Biol. Chem. 268, 20747-20755.
5. Uelmen, P. J., Oka, K., Sullivan, M., Chang, C. C. Y., Chang, T. Y. & Chan, L. (1995) J. Biol. Chem. 270, 26192-26201.
6. Meiner, V., Tam, C., Gunn, M. D., Dong, L.-M., Weisgraber, K. H., Novak, S., Myers, H. M., Erickson, S. K. & Farese, R. V., Jr. (1997) J. Lipid Res. 38, 1928-1933.
7. Cases, S., Novak, S., Zheng, Y.-W., Myers, H. M., Lear, S. R., Sande, E., Welch, C. B., Lusis, A. J., Spencer, T. A., Krause, B. R., et al. (1998) J. Biol. Chem. 273, 26755-26764.
8. Anderson, R. A., Joyce, C., Davis, M., Reagan, J. W., Clark, M., Shelness, G. S. & Rudel, L. L. (1998) J. Biol. Chem. 273, 26747-26754.
9. Oelkers, P., Behari, A., Cromley, D., Billheimer, J. T. & Sturley, S. L. (1998) J. Biol. Chem. 273, 26765-26771.
10. Meiner, V. L., Cases, S., Myers, H. M., Sande, E. R., Bellosta, S., Schambelan, M., Pitas, R. E., McGuire, J., Herz, J. & Farese, R. V., Jr. (1996) Proc. Natl. Acad. Sci. USA 93, 14041-14046.
11. Accad, M., Smith, S. J., Newland, D. L., Sanan, D. A., King, L. E., Jr., Linton, M. F., Fazio, S. & Farese, R. V., Jr. (2000) J. Clin. Invest. 105, 711-719.
12. Yagyu, H., Kitamine, T., Osuga, J.-I., Tozawa, R.-I., Chen, Z., Kaji, Y., Oka, T., Perrey, S., Tamura, Y., Ohashi, K., et al. (2000) J. Biol. Chem. 275, 21324-21330.
13. Fazio, S., Major, A. S., Swift, L. L., Gleaves, L. A., Accad, M., Linton, M. F. & Farese, R. V., Jr. (2001) J. Clin. Invest. 107, 163-171.
14. Buhman, K. K., Accad, M., Novak, S., Choi, R. S., Wong, J. S., Hamilton, R. L., Turley, S. & Farese, R. V., Jr. (2000) Nat. Med. 6, 1341-1347.
15. Plump, A. S., Smith, J. D., Hayek, T., Aalto-Setälä, K., Walsh, A., Verstuyft, J. G., Rubin, E. M. & Breslow, J. L. (1992) Cell 71, 343-353.
16. Zhang, S. H., Reddick, R. L., Piedrahita, J. A. & Maeda, N. (1992) Science 258, 468-471.
17. Windaus, A. (1910) Hoppe-Seyler's Z. Physiol. Chem. 67, 174-176.
18. Grundy, S. M. & Vega, G. L. (1992) Arch. Intern. Med. 152, 28-34.
19. Miller, M. (1999) Clin. Cardiol. 22, II-1-6.
20. Horie, Y., Fazio, S., Westerlund, J. R., Weisgraber, K. H. & Rall, S. C., Jr. (1992) J. Biol. Chem. 267, 1962-1968.
21. McCormick, S. P. A., Ng, J. K., Véniant, M., Borén, J., Pierotti, V., Flynn, L. M., Grass, D. S., Connolly, A. & Young, S. G. (1996) J. Biol. Chem. 271, 11963-11970.
22. Palinski, W., Tangirala, R. K., Miller, E., Young, S. G. & Witztum, J. L. (1995) Arterioscler. Thromb. Vasc. Biol. 15, 1569-1576.
23. Terasawa, Y., Ladha, Z., Leonard, S. W., Morrow, J. D., Newland, D., Sanan, D., Packer, L., Traber, M. G. & Farese, R. V., Jr. (2000) Proc. Natl. Acad. Sci. USA 97, 13830-13834.
24. Parks, J. S., Gebre, A. K. & Furbee, J. W. (1999) Methods Mol. Biol. 109, 123-131.
25. Bligh, E. G. & Dyer, W. J. (1959) Can. J. Biochem. Physiol. 37, 911-917.
26. Furbee, J. W., Jr., Francone, O. & Parks, J. S. (2002) J. Lipid Res. 43, 428-437.
27. Kane, J. P. & Havel, R. J. (2001) in The Metabolic and Molecular Bases of Inherited Disease, eds. Scriver, C. R., Beaudet, A. L., Sly, W. S., Valle, D., Childs, B., Kinzler, K. W. & Vogelstein, B. (McGraw-Hill, New York), Vol. 2, pp. 2717-2752.
28. Sniderman, A., Shapiro, S., Marpole, D., Skinner, B., Teng, B. & Kwiterovich, P. O., Jr. (1980) Proc. Natl. Acad. Sci. USA 77, 604-608.
29. Trigatti, B., Rigotti, A. & Kreiger, M. (2000) Curr. Opin. Lipidol. 11, 123-131.
30. Arai, T., Rinninger, F., Varban, L., Fairchild-Huntress, V., Liang, C.-P., Chen, W., Seo, T., Deckelbaum, R., Huszar, D. & Tall, A. R. (1999) Proc. Natl. Acad. Sci. USA 96, 12050-12055.
31. Carr, T. P., Parks, J. S. & Rudel, L. L. (1992) Arterioscler. Thromb. 12, 1274-1283.
32. Rudel, L. L., Davis, M., Sawyer, J., Shah, R. & Wallace, J. (2002) J. Biol. Chem. 277, 31401-31406.
33. Grundy, S. M. (1999) Am. J. Cardiol. 83, 25F-29F.
34. Rubins, H. B. (2000) J. Cardiovasc. Risk 7, 339-345.
35. Berard, A. M., Foger, B., Remaley, A., Shamburek, R., Vaisman, B. L., Talley, G., Paigen, B., Hoyt, R. F., Jr., Marcovina, S., Brewer, H. B., Jr., et al. (1997) Nat. Med. 3, 744-749.
36. Mehlum, A., Muri, M., Hagve, T. A., Solberg, L. A. & Prydz, H. (1997) Acta Pathol. Microbiol. Scand. 105, 861-868.
37. Furbee, J. W., Jr., & Parks, J. S. (2002) Atherosclerosis 165, 89-100.
38. Bocan, T. M. A., Krause, B. R., Rosebury, W. S., Mueller, S. B., Lu, X., Dagle, C., Major, T., Lathia, C. & Lee, H. (2000) Arterioscler. Thromb. Vasc. Biol. 20, 70-79.
39. Delsing, D. J. M., Offerman, E. H., van Duyvenvoorde, W., van der Boom, H., de Wit, E. C. M., Gijbels, M. J. J., van der Laarse, A., Jukema, J. W., Havekes, L. M., et al. (2001) Circulation 103, 1778-1786.
40. Kusunoki, J., Hansoty, D. K., Aragane, K., Fallon, J. T., Badimon, J. J. & Fisher, E. A. (2001) Circulation 103, 2604-2609.