Human hormone-sensitive lipase: Genetic mapping, identification of a new dinucleotide repeat, and association with obesity and NIDDM

Diabetes

Volumn 47, Issue 2, 1998, Pages 284-286

  Magré, Jocelyne ^a   Laurell, Henrik ^a   Fizames, Cécile ^b   Antoine, Pierre J ^a   Dib, Colette ^b   Vigouroux, Corinne ^a   Bourut, Charlotte ^a   Capeau, Jacqueline ^a   Weissenbach, Jean ^b   Langin, Dominique ^a  

^a INSERM   (France)

^b GÉNÉTHON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

TRIACYLGLYCEROL LIPASE;

ADULT; AGED; ALLELE; ARTICLE; CHROMOSOME 19Q; CONTROLLED STUDY; DINUCLEOTIDE REPEAT; FATTY ACID METABOLISM; FEMALE; GENE MAPPING; GENETIC LINKAGE; GENETIC POLYMORPHISM; HETEROZYGOTE; HORMONE SENSITIVITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL;

EID: 0031912535     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.47.2.284     Document Type: Article

References (7)

1. McCarthy MI, Froguel P, Hitman GA: The genetics of non-insulin-dependent diabetes mellitus: tools and aims. Diabetologia 37:959-968, 1994
2. Boden G: Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 46:0-10, 1997
3. Langin D, Laurell H, Stenson Holst L, Belfrage P, Holm C: Gene organization and primary structure of human hormone-sensitive lipase: possible significance of a sequence homology with a lipase of Moraxella TA 144, an antarctic bacterium. Proc Natl Acad Sci USA 90:4897-4901, 1993
4. Levitt RC, Liu Z, Nouri N, Meyers DA, Brandriff B, Mohrenweiser HM: Mapping of the gene for hormone sensitive lipase (LJPE) to chromosome 19q13.1 kq13.2. Cytogenet Cell Genet 69:211-214, 1995
5. Vignal A, Gyapay G, Hazan J, Nguyen S, Dupraz C, Cheron N, Becuwe N, Tranchant M, Weissenbach J: A non radioactive multiplex procedure for genotyping of microsatellite markers. In Gene and Chromosome Analysis, part A. Adolph KW, Ed. San Diego, CA, Academic 1:211-221, 1993
6. Dib C, Fauré S, Fizames C, Samson D, Drouot N, Vignal A, Millasseau P, Marc S, Hazan J, Seboun E, Lathrop M, Gyapay G, Morissette J, Weissenbach J: A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature 380:152-154, 1996
7. Lathrop GM, Lalouel JM; Easy calculation of lod scores and genetic risk on small computers. Am J Hum Genet 36:460-465, 1984