Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 13, 2001, Pages 7522-7527

  Kim, Jason K ^a   Fillmore, Jonathan J ^a   Chen, Yan ^a   Yu, Chunli ^a   Moore, Irene K ^a   Pypaert, Marc ^a   Lutz, E Peer ^b   Kako, Yuko ^b   Velez Carrasco, Wanda ^c   Goldberg, Ira J ^b   Breslow, Jan L ^c   Shulman, Gerald I ^a,d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Liver; Skeletal muscle

Indexed keywords

ACYL COENZYME A; CERAMIDE; DIACYLGLYCEROL; FATTY ACID DERIVATIVE; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; LIPOPROTEIN LIPASE; PHOSPHATIDYLINOSITOL 3 KINASE; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCONEOGENESIS; GLUCOSE TRANSPORT; INSULIN RESISTANCE; LIPID METABOLISM; LIVER; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; TRANSGENIC MOUSE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOOD GLUCOSE; FATTY ACIDS, NONESTERIFIED; GLUCAGON; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; HETEROZYGOTE; INSULIN; INSULIN RESISTANCE; LEPTIN; LIPOPROTEIN LIPASE; LIVER; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUSCLE, SKELETAL; ORGAN SPECIFICITY; PHOSPHOPROTEINS; SIGNAL TRANSDUCTION; TRIGLYCERIDES;

EID: 0035912744     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.121164498     Document Type: Article

References (34)