Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1

Nature Medicine

Volumn 16, Issue 11, 2010, Pages 1295-1298

  Herker, Eva ^a,b   Harris, Charles ^a,b,c   Hernandez, Céline ^d   Carpentier, Arnaud ^d   Kaehlcke, Katrin ^a   Rosenberg, Arielle R ^d   Farese, Robert V ^a,b,c   Ott, Melanie ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^d UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; DIACYLGLYCEROL ACYLTRANSFERASE 1; DIACYLGLYCEROL ACYLTRANSFERASE 1 INHIBITOR; DIACYLGLYCEROL ACYLTRANSFERASE 2; FAT DROPLET; RNA; UNCLASSIFIED DRUG;

ANTIVIRAL THERAPY; ARTICLE; CELL MIGRATION; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SYNTHESIS; GENE EXPRESSION; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; VIRION; VIRUS CORE; VIRUS NUCLEOCAPSID; VIRUS PARTICLE; VIRUS REPLICATION; VIRUS TITRATION; VIRUS VIRULENCE;

DIACYLGLYCEROL O-ACYLTRANSFERASE; HEK293 CELLS; HEPACIVIRUS; HUMANS; IMMUNOPRECIPITATION; TRANSFECTION; VIRION; VIRUS ASSEMBLY;

HEPATITIS C VIRUS;

EID: 78149359508     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2238     Document Type: Article

References (20)

1. Moradpour, D., Penin, F. & Rice, C.M. Nat. Rev. Microbiol. 5, 453-463 (2007).
2. Miyanari, Y. et al. Nat. Cell Biol. 9, 1089-1097 (2007).
3. Roingeard, P., Hourioux, C., Blanchard, E. & Prensier, G. Histochem. Cell Biol. 130, 561-566 (2008).
4. Boulant, S., Targett-Adams, P. & McLauchlan, J. J. Gen. Virol. 88, 2204-2213 (2007).
5. Huang, H. et al. Proc. Natl. Acad. Sci. USA 104, 5848-5853 (2007).
6. Chang, K.S., Jiang, J., Cai, Z. & Luo, G. J. Virol. 81, 13783-13793 (2007).
7. Gastaminza, P. et al. J. Virol. 82, 2120-2129 (2008).
8. Farese, R.V. Jr. & Walther, T.C. Cell 139, 855-860 (2009).
9. Yen, C.L., Stone, S.J., Koliwad, S., Harris, C. & Farese, R.V. Jr. J. Lipid Res. 49, 2283-2301 (2008).
10. Smith, S.J. et al. Nat. Genet. 25, 87-90 (2000).
11. Stone, S.J. et al. J. Biol. Chem. 279, 11767-11776 (2004).
12. Wakita, T. et al. Nat. Med. 11, 791-796 (2005).
13. Lindenbach, B.D. et al. Science 309, 623-626 (2005).
14. Zhong, J. et al. Proc. Natl. Acad. Sci. USA 102, 9294-9299 (2005).
15. Podevin, P. et al. Gastroenterology 10.1053/j.gastro.2010.06.058 (2010).
16. Barba, G. et al. Proc. Natl. Acad. Sci. USA 94, 1200-1205 (1997).
17. Selby, M.J. et al. J. Gen. Virol. 74, 1103-1113 (1993).
18. McLauchlan, J., Lemberg, M.K., Hope, G. & Martoglio, B. EMBO J. 21, 3980-3988 (2002).
19. Ma, Y., Yates, J., Liang, Y., Lemon, S.M. & Yi, M. J. Virol. 82, 7624-7639 (2008).
20. Targett-Adams, P., Boulant, S. & McLauchlan, J. J. Virol. 82, 2182-2195 (2008).