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Volumn 40, Issue , 2013, Pages 71-132

Catalytic asymmetric strategies for the synthesis of 3,3-disubstituted oxindoles

Author keywords

Alkaloids; Asymmetric catalysis; Isatins; Organocatalysis; Oxindoles

Indexed keywords


EID: 84879893038     PISSN: 15725995     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-444-59603-1.00004-7     Document Type: Chapter
Times cited : (17)

References (219)
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    • For a related approach, using silyl enol ethers derived from 3-carbalkoxyoxindoles as substrates, see
    • For a related approach, using silyl enol ethers derived from 3-carbalkoxyoxindoles as substrates, see: B.M. Trost, and K.M. Brennan Org. Lett. 8 2006 2027 2030
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    • For a more recent approach, in which a different and more involved tertiary amine thiourea catalyst exhibiting both central and axial chirality is also used for the asymmetric Michael addition of N-Boc 3-aryloxindoles to methyl vinyl ketone, see
    • For a more recent approach, in which a different and more involved tertiary amine thiourea catalyst exhibiting both central and axial chirality is also used for the asymmetric Michael addition of N-Boc 3-aryloxindoles to methyl vinyl ketone, see: H.J. Lee, S.B. Woo, and D.Y. Kim Molecules 17 2012 7523 7532
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    • For the L-proline/trans-2,5-dimethylpiperazine catalysis of the Michael addition of 3-substituted oxindoles to cyclic enones, that takes place with moderate diastereoselectivities and with variable enantioselectivities, see
    • For the L-proline/trans-2,5-dimethylpiperazine catalysis of the Michael addition of 3-substituted oxindoles to cyclic enones, that takes place with moderate diastereoselectivities and with variable enantioselectivities, see: M.H. Freund, and S.B. Tsogoeva Synlett 2011 503 507
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    • For a subsequent similar approach, using commercially available (DHQD)2PYR Sharpless ligand as the organocatalyst, see
    • For a subsequent similar approach, using commercially available (DHQD)2PYR Sharpless ligand as the organocatalyst, see: J.-S. Yu, F. Zhou, Y.-L. Liu, and J. Zhou Beilstein J. Org. Chem. 8 2012 1360 1365
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    • For a previous less stereoselective version of the same reaction using chiral phosphinothiourea catalysts, see
    • For a previous less stereoselective version of the same reaction using chiral phosphinothiourea catalysts, see: C.-C. Wang, and X.-Y. Wu Tetrahedron 67 2011 2974 2978
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.