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3 was not beneficial, even after 5 h. In both these reactions, Pd black was observed, suggesting that no active catalyst remained in solution.
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48
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77952346772
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This reaction also proceeds with protected oxindoles. For an example, see ref 11g
-
This reaction also proceeds with protected oxindoles. For an example, see ref 11g.
-
-
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49
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77952400237
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-
note
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3 we were able to obtain the desired product in 61% yield along with 31% recovered 7 after 12 h at reflux.
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50
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NAr reactions of halo-oxazoles, see
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