Organocatalytic conjugate additions of acetylacetone to 3-ylideneoxindoles: A direct access to highly enantioenriched oxindole derivatives

Synthesis

Volumn , Issue 12, 2011, Pages 1847-1852

  Duan, Shu Wen ^a   Lu, Hai Hua ^a   Zhang, Fu Gen ^a   Xuan, Jun ^a   Chen, Jia Rong ^a   Xiao, Wen Jing ^a  

^a CENTRAL CHINA NORMAL UNIVERSITY   (China)

Author keywords

3 ylideneoxindole; bifunctional activation; conjugate addition; organocatalysis; oxindole

Indexed keywords

3-YLIDENEOXINDOLE; BIFUNCTIONAL; CONJUGATE ADDITION; ORGANOCATALYSIS; OXINDOLE;

ACETONE; ENANTIOSELECTIVITY; REACTION KINETICS;

ADDITION REACTIONS;

3 YLIDENEOXINDOLE DERIVATIVE; ACETYLACETONE; OXINDOLE; PROPYL 2 (1 METHYL 2 OXOINDOLIN 3 YL) 3 NITROPROPANOATE; PROPYL 3 ACETYL 2 (1 METHYL 2 OXOINDOLIN 3 YL) 4 OXOPENTANOATE; PROPYL 3 ACETYL 2 (1,5 DIMETHYL 2 OXOINDOLIN 3 YL) 4 OXOPENTANOATE; PROPYL 3 ACETYL 2 (5 BROMO 1 METHYL 2 OXOINDOLIN 3 YL) 4 OXOPENTANOATE; PROPYL 3 ACETYL 2 (5 FLUORO 1 METHYL 2 OXOINDOLIN 3 YL) 4 OXOPENTANOATE; PROPYL 3 ACETYL 2 (6 BROMO 1 METHYL 2 OXOINDOLIN 3 YL) 4 OXOPENTANOATE; PROPYL 3 ACETYL 2 (6 BROMO 5 CHLORO 1 METHYL 2 OXOINDOLIN 3 YL) 4 OXOPENTANOATE; PROPYL 3 ACETYL 2 (6 CHLORO 1 METHYL 2 OXOINDOLIN 3 YL) 4 OXOPENTANOATE; PROPYL 3 ACETYL 2 (7 FLUORO 1 METHYL 2 OXOINDOLIN 3 YL) 4 OXOPENTANOATE; PROPYL 3 ACETYL 2 [1 METHYL 2 OXO 5 (TRIFLUOROMETHOXY)INDOLIN 3 YL] 4 OXOPENTANOATE; UNCLASSIFIED DRUG;

ADDITION REACTION; ARTICLE; CATALYSIS; DRUG DETERMINATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOSELECTIVITY; SOLVENT EFFECT;

EID: 79958142012     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1260463     Document Type: Article

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