Intramolecular aldol reaction of N-Acylated (2-Aminophenyl)-α- oxoacetic Acids: Rapid access to Tri- and tetracyclic 1,2-dihydroquinolin-2(1 H)-ones

Journal of Organic Chemistry

Volumn 75, Issue 10, 2010, Pages 3465-3468

  Hellal, Malik ^a   Cuny, Gregory D ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOUR-STEP SYNTHESIS; INTRAMOLECULAR ALDOL REACTIONS;

CONDENSATION REACTIONS; SYNTHESIS (CHEMICAL);

CYCLIZATION;

2 AMINOPHENYL ALPHA OXOACETIC ACID; 2,3,4,6 TETRAHYDROBENZO[C][2,6]NAPHTHYRIDINE 1,5 DIONE; ACETIC ACID DERIVATIVE; DIHYDROQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ACYLATION; ALDOL REACTION; ARTICLE; CYCLIZATION; DRUG ACETYLATION; DRUG SYNTHESIS; MOLECULAR INTERACTION; SUBSTITUTION REACTION;

ACETIC ACIDS; ISATIN; MOLECULAR STRUCTURE; QUINOLONES; STEREOISOMERISM;

EID: 77952477641     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo1003339     Document Type: Article

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