Asymmetric conjugate addition of oxindoles to 2-chloroacrylonitrile: A highly effective organocatalytic strategy for simultaneous construction of 1,3-nonadjacent stereocenters leading to chiral pyrroloindolines

Chemistry - A European Journal

Volumn 16, Issue 48, 2010, Pages 14290-14294

  Li, Xin ^a   Luo, Sanzhong ^a   Cheng, Jin Pei ^b  

^a INSTITUTE OF CHEMISTRY   (China)

^b NANKAI UNIVERSITY   (China)

Author keywords

Michael addition; natural products; organocatalysis; oxindoles; quaternary center

Indexed keywords

MICHAEL ADDITIONS; NATURAL PRODUCTS; ORGANOCATALYSIS; OXINDOLES; QUATERNARY CENTERS;

ADDITION REACTIONS; CATALYSIS; RATE CONSTANTS; THIOUREAS; UREA;

REACTION KINETICS;

2 CHLOROACRYLONITRILE; 2-CHLOROACRYLONITRILE; ACRYLONITRILE; CHLORINATED HYDROCARBON; DRUG DERIVATIVE; INDOLE ALKALOID; INDOLE DERIVATIVE; OXINDOLE; PYRROLE DERIVATIVE; THIOUREA;

ARTICLE; CATALYSIS; CHEMISTRY; COMBINATORIAL CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

ACRYLONITRILE; CATALYSIS; COMBINATORIAL CHEMISTRY TECHNIQUES; HYDROCARBONS, CHLORINATED; INDOLE ALKALOIDS; INDOLES; PYRROLES; STEREOISOMERISM; THIOUREA;

EID: 78651258842     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201002563     Document Type: Article

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