메뉴 건너뛰기




Volumn 57, Issue , 2013, Pages 28-37

Environmental and pharmacological modulations of cellular plasticity: Role in the pathophysiology and treatment of depression

Author keywords

Animal models; Antidepressants; Early life stress; Exercise; Major depressive disorder; Omega 3 fatty acids; Stress

Indexed keywords

ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; GLYCOGEN SYNTHASE KINASE 3; LITHIUM SALT; METABOTROPIC RECEPTOR 2 ANTAGONIST; METABOTROPIC RECEPTOR 3 ANTAGONIST; METABOTROPIC RECEPTOR ANTAGONIST; MOOD STABILIZER; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROGENIC DIFFERENTIATION FACTOR; NEUROTROPHIC FACTOR; OMEGA 3 FATTY ACID; SOMATOMEDIN C; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 84879779725     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.05.022     Document Type: Review
Times cited : (75)

References (210)
  • 1
    • 1542380913 scopus 로고    scopus 로고
    • Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression
    • Adlard P.A., Cotman C.W. Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression. Neuroscience 2004, 124:985-992.
    • (2004) Neuroscience , vol.124 , pp. 985-992
    • Adlard, P.A.1    Cotman, C.W.2
  • 2
    • 0344629700 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity
    • Alder J., et al. Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity. J. Neurosci. 2003, 23:10800-10808.
    • (2003) J. Neurosci. , vol.23 , pp. 10800-10808
    • Alder, J.1
  • 3
    • 0032100238 scopus 로고    scopus 로고
    • Do early-life events permanently alter behavioral and hormonal responses to stressors?
    • Anisman H., et al. Do early-life events permanently alter behavioral and hormonal responses to stressors?. Int. J. Dev. Neurosci. 1998, 16:149-164.
    • (1998) Int. J. Dev. Neurosci. , vol.16 , pp. 149-164
    • Anisman, H.1
  • 4
    • 79960057257 scopus 로고    scopus 로고
    • NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
    • Autry A.E., et al. NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses. Nature 2011, 1-7.
    • (2011) Nature , pp. 1-7
    • Autry, A.E.1
  • 5
    • 0033799072 scopus 로고    scopus 로고
    • Exercise treatment for major depression: maintenance of therapeutic benefit at 10 months
    • Babyak M., et al. Exercise treatment for major depression: maintenance of therapeutic benefit at 10 months. Psychosom. Med. 2000, 62:633-638.
    • (2000) Psychosom. Med. , vol.62 , pp. 633-638
    • Babyak, M.1
  • 6
    • 84861199485 scopus 로고    scopus 로고
    • Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants
    • Baj G., et al. Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants. Neuropsychopharmacology 2012, 37:1600-1611.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 1600-1611
    • Baj, G.1
  • 7
    • 84872773879 scopus 로고    scopus 로고
    • Complementary and alternative medicine use among adults and children: United States, 2007
    • Barnes P.M., et al. Complementary and alternative medicine use among adults and children: United States, 2007. Natl. Health Stat. Rep. 2008, 1-23.
    • (2008) Natl. Health Stat. Rep. , pp. 1-23
    • Barnes, P.M.1
  • 8
    • 15744402723 scopus 로고    scopus 로고
    • The reinforcing property and the rewarding aftereffect of wheel running in rats: a combination of two paradigms
    • Belke T.W., Wagner J.P. The reinforcing property and the rewarding aftereffect of wheel running in rats: a combination of two paradigms. Behav. Processes 2005, 68:165-172.
    • (2005) Behav. Processes , vol.68 , pp. 165-172
    • Belke, T.W.1    Wagner, J.P.2
  • 9
    • 39149129965 scopus 로고    scopus 로고
    • Stress sensitivity and resilience in the chronic mild stress rat model of depression; an in situ hybridization study
    • Bergström A., et al. Stress sensitivity and resilience in the chronic mild stress rat model of depression; an in situ hybridization study. Brain Res. 2008, 1196:41-52.
    • (2008) Brain Res. , vol.1196 , pp. 41-52
    • Bergström, A.1
  • 10
    • 0033969685 scopus 로고    scopus 로고
    • Antidepressant effects of ketamine in depressed patients
    • Berman R.M., et al. Antidepressant effects of ketamine in depressed patients. Biol. Psychiatry 2000, 47:351-354.
    • (2000) Biol. Psychiatry , vol.47 , pp. 351-354
    • Berman, R.M.1
  • 11
    • 85028117370 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice
    • Beurel E., et al. Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice. Mol. Psychiatry 2011, 16:1068-1070.
    • (2011) Mol. Psychiatry , vol.16 , pp. 1068-1070
    • Beurel, E.1
  • 12
    • 22344433956 scopus 로고    scopus 로고
    • The antidepressant effect of running is associated with increased hippocampal cell proliferation
    • Bjørnebekk A., et al. The antidepressant effect of running is associated with increased hippocampal cell proliferation. Int. J. Neuropsychopharmacol. 2005, 8:357-368.
    • (2005) Int. J. Neuropsychopharmacol. , vol.8 , pp. 357-368
    • Bjørnebekk, A.1
  • 13
    • 77955637265 scopus 로고    scopus 로고
    • Serum and plasma BDNF levels in major depression: a replication study and meta-analyses
    • Bocchio-Chiavetto L., et al. Serum and plasma BDNF levels in major depression: a replication study and meta-analyses. World J. Biol. Psychiatry 2010, 11:763-773.
    • (2010) World J. Biol. Psychiatry , vol.11 , pp. 763-773
    • Bocchio-Chiavetto, L.1
  • 14
    • 70349118076 scopus 로고    scopus 로고
    • Antidepressants increase neural progenitor cells in the human hippocampus
    • Boldrini M., et al. Antidepressants increase neural progenitor cells in the human hippocampus. Neuropsychopharmacology 2009, 34:2376-2389.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 2376-2389
    • Boldrini, M.1
  • 15
    • 0026085109 scopus 로고
    • Essentiality of omega 3 fatty acids for brain structure and function
    • Bourre J.M., et al. Essentiality of omega 3 fatty acids for brain structure and function. World Rev. Nutr. Diet. 1991, 66:103-117.
    • (1991) World Rev. Nutr. Diet. , vol.66 , pp. 103-117
    • Bourre, J.M.1
  • 16
    • 83455229501 scopus 로고    scopus 로고
    • The mGluR7 allosteric agonist AMN082 produces antidepressant-like effects by modulating glutamatergic signaling
    • Bradley S.R., et al. The mGluR7 allosteric agonist AMN082 produces antidepressant-like effects by modulating glutamatergic signaling. Pharmacol. Biochem. Behav. 2012, 101:35-40.
    • (2012) Pharmacol. Biochem. Behav. , vol.101 , pp. 35-40
    • Bradley, S.R.1
  • 17
    • 0033970356 scopus 로고    scopus 로고
    • Hippocampal volume reduction in major depression
    • Bremner J.D., et al. Hippocampal volume reduction in major depression. Am. J. Psychiatry 2000, 157:115-118.
    • (2000) Am. J. Psychiatry , vol.157 , pp. 115-118
    • Bremner, J.D.1
  • 18
    • 55549139122 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression
    • Brunoni A.R., et al. A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. Int. J. Neuropsychopharmacol. 2008, 11:1169-1180.
    • (2008) Int. J. Neuropsychopharmacol. , vol.11 , pp. 1169-1180
    • Brunoni, A.R.1
  • 19
    • 33646097451 scopus 로고    scopus 로고
    • BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects
    • Bueller J.A., et al. BDNF Val66Met allele is associated with reduced hippocampal volume in healthy subjects. Biol. Psychiatry 2006, 59:812-815.
    • (2006) Biol. Psychiatry , vol.59 , pp. 812-815
    • Bueller, J.A.1
  • 20
    • 4143102415 scopus 로고    scopus 로고
    • Docosahexaenoic acid promotes neurite growth in hippocampal neurons
    • Calderon F., Kim H.-Y. Docosahexaenoic acid promotes neurite growth in hippocampal neurons. J. Neurochem. 2004, 90:979-988.
    • (2004) J. Neurochem. , vol.90 , pp. 979-988
    • Calderon, F.1    Kim, H.-Y.2
  • 21
    • 0033968689 scopus 로고    scopus 로고
    • The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat
    • Caldji C., et al. The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat. Neuropsychopharmacology 2000, 22:219-229.
    • (2000) Neuropsychopharmacology , vol.22 , pp. 219-229
    • Caldji, C.1
  • 22
    • 1842481232 scopus 로고    scopus 로고
    • Lower hippocampal volume in patients suffering from depression: a meta-analysis
    • Campbell S., et al. Lower hippocampal volume in patients suffering from depression: a meta-analysis. Am. J. Psychiatry 2004, 161:598-607.
    • (2004) Am. J. Psychiatry , vol.161 , pp. 598-607
    • Campbell, S.1
  • 23
    • 13444254125 scopus 로고    scopus 로고
    • Antidepressant-like effects of uridine and omega-3 fatty acids are potentiated by combined treatment in rats
    • Carlezon W.A., et al. Antidepressant-like effects of uridine and omega-3 fatty acids are potentiated by combined treatment in rats. Biol. Psychiatry 2005, 57:343-350.
    • (2005) Biol. Psychiatry , vol.57 , pp. 343-350
    • Carlezon, W.A.1
  • 24
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
    • Caspi A., et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003, 301:386-389.
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1
  • 25
    • 33846903377 scopus 로고    scopus 로고
    • Role of neurotrophic factors in depression
    • Castrén E., et al. Role of neurotrophic factors in depression. Curr. Opin. Pharmacol. 2007, 7:18-21.
    • (2007) Curr. Opin. Pharmacol. , vol.7 , pp. 18-21
    • Castrén, E.1
  • 26
    • 34249899704 scopus 로고    scopus 로고
    • A history of caloric restriction induces neurochemical and behavioral changes in rats consistent with models of depression
    • Chandler-Laney P.C., et al. A history of caloric restriction induces neurochemical and behavioral changes in rats consistent with models of depression. Pharmacol. Biochem. Behav. 2007, 87:104-114.
    • (2007) Pharmacol. Biochem. Behav. , vol.87 , pp. 104-114
    • Chandler-Laney, P.C.1
  • 27
    • 2442673159 scopus 로고    scopus 로고
    • Life stress, genes, and depression: multiple pathways lead to increased risk and new opportunities for intervention
    • Charney D.S., Manji H.K. Life stress, genes, and depression: multiple pathways lead to increased risk and new opportunities for intervention. Sci. STKE 2004, 2004:re5.
    • (2004) Sci. STKE , vol.2004
    • Charney, D.S.1    Manji, H.K.2
  • 28
    • 70349454084 scopus 로고    scopus 로고
    • Running exercise-induced up-regulation of hippocampal brain-derived neurotrophic factor is CREB-dependent
    • Chen M.J., Russo-Neustadt A.A. Running exercise-induced up-regulation of hippocampal brain-derived neurotrophic factor is CREB-dependent. Hippocampus 2009, 19:962-972.
    • (2009) Hippocampus , vol.19 , pp. 962-972
    • Chen, M.J.1    Russo-Neustadt, A.A.2
  • 29
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
    • Chen B., et al. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol. Psychiatry 2001, 50:260-265.
    • (2001) Biol. Psychiatry , vol.50 , pp. 260-265
    • Chen, B.1
  • 30
    • 2342550552 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons
    • Chen Z.-Y., et al. Variant brain-derived neurotrophic factor (BDNF) (Met66) alters the intracellular trafficking and activity-dependent secretion of wild-type BDNF in neurosecretory cells and cortical neurons. J. Neurosci. 2004, 24:4401-4411.
    • (2004) J. Neurosci. , vol.24 , pp. 4401-4411
    • Chen, Z.-Y.1
  • 31
    • 33749649795 scopus 로고    scopus 로고
    • Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior
    • Chen Z.-Y., et al. Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior. Science 2006, 314:140-143.
    • (2006) Science , vol.314 , pp. 140-143
    • Chen, Z.-Y.1
  • 32
    • 70349482565 scopus 로고    scopus 로고
    • Dendritic trafficking of BDNF mRNA is mediated by translin and blocked by the G196A (Val66Met) mutation
    • Chiaruttini C., et al. Dendritic trafficking of BDNF mRNA is mediated by translin and blocked by the G196A (Val66Met) mutation. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:16481-16486.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 16481-16486
    • Chiaruttini, C.1
  • 33
    • 34250640687 scopus 로고    scopus 로고
    • Long-chain omega-3 fatty acid intake is associated positively with corticolimbic gray matter volume in healthy adults
    • Conklin S.M., et al. Long-chain omega-3 fatty acid intake is associated positively with corticolimbic gray matter volume in healthy adults. Neurosci. Lett. 2007, 421:209-212.
    • (2007) Neurosci. Lett. , vol.421 , pp. 209-212
    • Conklin, S.M.1
  • 34
    • 67349271533 scopus 로고    scopus 로고
    • Docosahexaenoic acid significantly stimulates immediate early response genes and neurite outgrowth
    • Dagai L., et al. Docosahexaenoic acid significantly stimulates immediate early response genes and neurite outgrowth. Neurochem. Res. 2009, 34:867-875.
    • (2009) Neurochem. Res. , vol.34 , pp. 867-875
    • Dagai, L.1
  • 35
    • 65649125633 scopus 로고    scopus 로고
    • Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression
    • David D.J., et al. Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron 2009, 62:479-493.
    • (2009) Neuron , vol.62 , pp. 479-493
    • David, D.J.1
  • 36
    • 30844456607 scopus 로고    scopus 로고
    • One generation of n-3 polyunsaturated fatty acid deprivation increases depression and aggression test scores in rats
    • DeMar J.C., et al. One generation of n-3 polyunsaturated fatty acid deprivation increases depression and aggression test scores in rats. J. Lipid Res. 2006, 47:172-180.
    • (2006) J. Lipid Res. , vol.47 , pp. 172-180
    • DeMar, J.C.1
  • 37
    • 0030997511 scopus 로고    scopus 로고
    • Activity wheel running reduces escape latency and alters brain monoamine levels after footshock
    • Dishman R.K., et al. Activity wheel running reduces escape latency and alters brain monoamine levels after footshock. Brain Res. Bull. 1997, 42:399-406.
    • (1997) Brain Res. Bull. , vol.42 , pp. 399-406
    • Dishman, R.K.1
  • 38
    • 0030935403 scopus 로고    scopus 로고
    • Subgenual prefrontal cortex abnormalities in mood disorders
    • Drevets W.C., et al. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 1997, 386:824-827.
    • (1997) Nature , vol.386 , pp. 824-827
    • Drevets, W.C.1
  • 39
    • 34250344214 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis as target for the treatment of depression
    • Drew M.R., Hen R. Adult hippocampal neurogenesis as target for the treatment of depression. CNS Neurol. Disord. Drug Targets 2007, 6:205-218.
    • (2007) CNS Neurol. Disord. Drug Targets , vol.6 , pp. 205-218
    • Drew, M.R.1    Hen, R.2
  • 40
    • 34547628672 scopus 로고    scopus 로고
    • Voluntary exercise impacts on the rat hypothalamic-pituitary-adrenocortical axis mainly at the adrenal level
    • Droste S.K., et al. Voluntary exercise impacts on the rat hypothalamic-pituitary-adrenocortical axis mainly at the adrenal level. Neuroendocrinology 2007, 86:26-37.
    • (2007) Neuroendocrinology , vol.86 , pp. 26-37
    • Droste, S.K.1
  • 41
    • 0035145760 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice
    • Duan W., et al. Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice. J. Neurochem. 2001, 76:619-626.
    • (2001) J. Neurochem. , vol.76 , pp. 619-626
    • Duan, W.1
  • 42
    • 3242745166 scopus 로고    scopus 로고
    • Depression: a case of neuronal life and death?
    • Duman R.S. Depression: a case of neuronal life and death?. Biol. Psychiatry 2004, 56:140-145.
    • (2004) Biol. Psychiatry , vol.56 , pp. 140-145
    • Duman, R.S.1
  • 43
    • 1642307557 scopus 로고    scopus 로고
    • Role of neurotrophic factors in the etiology and treatment of mood disorders
    • Duman R.S. Role of neurotrophic factors in the etiology and treatment of mood disorders. Neuromolecular Med. 2004, 5:11-25.
    • (2004) Neuromolecular Med. , vol.5 , pp. 11-25
    • Duman, R.S.1
  • 44
    • 28444447357 scopus 로고    scopus 로고
    • Neurotrophic factors and regulation of mood: role of exercise, diet and metabolism
    • Duman R.S. Neurotrophic factors and regulation of mood: role of exercise, diet and metabolism. Neurobiol. Aging 2005, 26(Suppl. 1):88-93.
    • (2005) Neurobiol. Aging , vol.26 , Issue.SUPPL. 1 , pp. 88-93
    • Duman, R.S.1
  • 45
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman R.S., Monteggia L.M. A neurotrophic model for stress-related mood disorders. Biol. Psychiatry 2006, 59:1116-1127.
    • (2006) Biol. Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 46
    • 84855297758 scopus 로고    scopus 로고
    • Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents
    • Duman R.S., Voleti B. Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents. Trends Neurosci. 2012, 35:47-56.
    • (2012) Trends Neurosci. , vol.35 , pp. 47-56
    • Duman, R.S.1    Voleti, B.2
  • 47
    • 33847308098 scopus 로고    scopus 로고
    • A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment
    • Duman C.H., et al. A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biol. Psychiatry 2007, 61:661-670.
    • (2007) Biol. Psychiatry , vol.61 , pp. 661-670
    • Duman, C.H.1
  • 48
    • 40049093899 scopus 로고    scopus 로고
    • Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice
    • Duman C.H., et al. Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice. Brain Res. 2008, 1199:148-158.
    • (2008) Brain Res. , vol.1199 , pp. 148-158
    • Duman, C.H.1
  • 49
    • 59649109108 scopus 로고    scopus 로고
    • Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise
    • Duman C.H., et al. Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise. Behav. Brain Res. 2009, 198:366-371.
    • (2009) Behav. Brain Res. , vol.198 , pp. 366-371
    • Duman, C.H.1
  • 50
    • 84892625938 scopus 로고    scopus 로고
    • Signaling pathways underlying the rapid antidepressant actions of ketamine
    • Duman R.S., et al. Signaling pathways underlying the rapid antidepressant actions of ketamine. Neuropharmacology 2011, 37:47-56.
    • (2011) Neuropharmacology , vol.37 , pp. 47-56
    • Duman, R.S.1
  • 51
    • 11144241830 scopus 로고    scopus 로고
    • Exercise treatment for depression: efficacy and dose response
    • Dunn A.L., et al. Exercise treatment for depression: efficacy and dose response. Am. J. Prev. Med. 2005, 28:1-8.
    • (2005) Am. J. Prev. Med. , vol.28 , pp. 1-8
    • Dunn, A.L.1
  • 52
    • 78149305869 scopus 로고    scopus 로고
    • A negative regulator of MAP kinase causes depressive behavior
    • Duric V., et al. A negative regulator of MAP kinase causes depressive behavior. Nat. Med. 2010, 16:1328-1332.
    • (2010) Nat. Med. , vol.16 , pp. 1328-1332
    • Duric, V.1
  • 53
    • 0042154427 scopus 로고    scopus 로고
    • Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects
    • Dwivedi Y., et al. Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch. Gen. Psychiatry 2003, 60:804-815.
    • (2003) Arch. Gen. Psychiatry , vol.60 , pp. 804-815
    • Dwivedi, Y.1
  • 54
    • 32844458346 scopus 로고    scopus 로고
    • ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf
    • Dwivedi Y., et al. ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf. Mol. Psychiatry 2006, 11:86-98.
    • (2006) Mol. Psychiatry , vol.11 , pp. 86-98
    • Dwivedi, Y.1
  • 55
    • 34548380457 scopus 로고    scopus 로고
    • Aberrant extracellular signal-regulated kinase (ERK) 5 signaling in hippocampus of suicide subjects
    • Dwivedi Y., et al. Aberrant extracellular signal-regulated kinase (ERK) 5 signaling in hippocampus of suicide subjects. Neuropsychopharmacology 2007, 32:2338-2350.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 2338-2350
    • Dwivedi, Y.1
  • 56
    • 84855332374 scopus 로고    scopus 로고
    • MTOR activation is required for the antidepressant effects of mGluR2/3 blockade
    • Dwyer J.M., et al. mTOR activation is required for the antidepressant effects of mGluR2/3 blockade. Int. J. Neuropsychopharmacol. 2011, 1-6.
    • (2011) Int. J. Neuropsychopharmacol. , pp. 1-6
    • Dwyer, J.M.1
  • 57
    • 0037462449 scopus 로고    scopus 로고
    • The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
    • Egan M.F., et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003, 112:257-269.
    • (2003) Cell , vol.112 , pp. 257-269
    • Egan, M.F.1
  • 58
    • 6044228097 scopus 로고    scopus 로고
    • Gene-environment interaction analysis of serotonin system markers with adolescent depression
    • Eley T.C., et al. Gene-environment interaction analysis of serotonin system markers with adolescent depression. Mol. Psychiatry 2004, 9:908-915.
    • (2004) Mol. Psychiatry , vol.9 , pp. 908-915
    • Eley, T.C.1
  • 59
    • 79952282659 scopus 로고    scopus 로고
    • The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met
    • Elzinga B.M., et al. The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met. Psychopharmacology (Berl) 2011, 214:319-328.
    • (2011) Psychopharmacology (Berl) , vol.214 , pp. 319-328
    • Elzinga, B.M.1
  • 60
    • 79952611543 scopus 로고    scopus 로고
    • Exercise training increases size of hippocampus and improves memory
    • Erickson K.I., et al. Exercise training increases size of hippocampus and improves memory. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:3017-3022.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 3017-3022
    • Erickson, K.I.1
  • 61
    • 0346751060 scopus 로고    scopus 로고
    • VEGF is necessary for exercise-induced adult hippocampal neurogenesis
    • Fabel K., et al. VEGF is necessary for exercise-induced adult hippocampal neurogenesis. Eur. J. Neurosci. 2003, 18:2803-2812.
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 2803-2812
    • Fabel, K.1
  • 62
    • 0442307920 scopus 로고    scopus 로고
    • Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo
    • Farmer J., et al. Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience 2004, 124:71-79.
    • (2004) Neuroscience , vol.124 , pp. 71-79
    • Farmer, J.1
  • 63
    • 0032078822 scopus 로고    scopus 로고
    • Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) study
    • Felitti V.J., et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) study. Am. J. Prev. Med. 1998, 14:245-258.
    • (1998) Am. J. Prev. Med. , vol.14 , pp. 245-258
    • Felitti, V.J.1
  • 64
    • 79151485368 scopus 로고    scopus 로고
    • Chronic ω-3 fatty acids supplementation promotes beneficial effects on anxiety, cognitive and depressive-like behaviors in rats subjected to a restraint stress protocol
    • Ferraz A.C., et al. Chronic ω-3 fatty acids supplementation promotes beneficial effects on anxiety, cognitive and depressive-like behaviors in rats subjected to a restraint stress protocol. Behav. Brain Res. 2011, 219:116-122.
    • (2011) Behav. Brain Res. , vol.219 , pp. 116-122
    • Ferraz, A.C.1
  • 65
    • 84855926398 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in adult hippocampal neurogenesis: Implications for the pathophysiology and treatment of depression
    • Fournier N.M., Duman R.S. Role of vascular endothelial growth factor in adult hippocampal neurogenesis: Implications for the pathophysiology and treatment of depression. Behav. Brain Res. 2011, 227:440-449.
    • (2011) Behav. Brain Res. , vol.227 , pp. 440-449
    • Fournier, N.M.1    Duman, R.S.2
  • 66
    • 33748968456 scopus 로고    scopus 로고
    • Omega-3 fatty acids and perinatal depression: a review of the literature and recommendations for future research
    • Freeman M.P. Omega-3 fatty acids and perinatal depression: a review of the literature and recommendations for future research. Prostaglandins Leukot. Essent. Fatty Acids 2006, 75:291-297.
    • (2006) Prostaglandins Leukot. Essent. Fatty Acids , vol.75 , pp. 291-297
    • Freeman, M.P.1
  • 67
    • 67649327144 scopus 로고    scopus 로고
    • Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety
    • Gatt J.M., et al. Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety. Mol. Psychiatry 2009, 14:681-695.
    • (2009) Mol. Psychiatry , vol.14 , pp. 681-695
    • Gatt, J.M.1
  • 68
    • 77957155780 scopus 로고    scopus 로고
    • Maternal separation with early weaning: a novel mouse model of early life neglect
    • George E.D., et al. Maternal separation with early weaning: a novel mouse model of early life neglect. BMC Neurosci. 2010, 11:123.
    • (2010) BMC Neurosci. , vol.11 , pp. 123
    • George, E.D.1
  • 69
    • 84855353747 scopus 로고    scopus 로고
    • Omega-3 fatty acid augmentation of citalopram treatment for patients with major depressive disorder
    • Gertsik L., et al. Omega-3 fatty acid augmentation of citalopram treatment for patients with major depressive disorder. J. Clin. Psychopharmacol. 2012, 32:61-64.
    • (2012) J. Clin. Psychopharmacol. , vol.32 , pp. 61-64
    • Gertsik, L.1
  • 70
    • 22144474412 scopus 로고    scopus 로고
    • Partial normalization of serum brain-derived neurotrophic factor in remitted patients after a major depressive episode
    • Gervasoni N., et al. Partial normalization of serum brain-derived neurotrophic factor in remitted patients after a major depressive episode. Neuropsychobiology 2005, 51:234-238.
    • (2005) Neuropsychobiology , vol.51 , pp. 234-238
    • Gervasoni, N.1
  • 71
    • 79961129713 scopus 로고    scopus 로고
    • Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants
    • Gorzalka B.B., Hill M.N. Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants. Prog. Neuropsychopharmacol. Biol. Psychiatry 2011, 35:1575-1585.
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , pp. 1575-1585
    • Gorzalka, B.B.1    Hill, M.N.2
  • 72
    • 84855354000 scopus 로고    scopus 로고
    • Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymorphism and the 5-HTT promoter polymorphism moderates the susceptibility to depressive disorders after childhood abuse
    • Grabe H.J., et al. Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymorphism and the 5-HTT promoter polymorphism moderates the susceptibility to depressive disorders after childhood abuse. Prog. Neuropsychopharmacol. Biol. Psychiatry 2012, 36:264-270.
    • (2012) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.36 , pp. 264-270
    • Grabe, H.J.1
  • 73
    • 0037386918 scopus 로고    scopus 로고
    • Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons
    • Greenwood B.N., et al. Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons. J. Neurosci. 2003, 23:2889-2898.
    • (2003) J. Neurosci. , vol.23 , pp. 2889-2898
    • Greenwood, B.N.1
  • 74
    • 13244277559 scopus 로고    scopus 로고
    • The consequences of uncontrollable stress are sensitive to duration of prior wheel running
    • Greenwood B.N., et al. The consequences of uncontrollable stress are sensitive to duration of prior wheel running. Brain Res. 2005, 1033:164-178.
    • (2005) Brain Res. , vol.1033 , pp. 164-178
    • Greenwood, B.N.1
  • 75
    • 52049127039 scopus 로고    scopus 로고
    • From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and function
    • Greer P.L., Greenberg M.E. From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and function. Neuron 2008, 59:846-860.
    • (2008) Neuron , vol.59 , pp. 846-860
    • Greer, P.L.1    Greenberg, M.E.2
  • 76
    • 84950170767 scopus 로고    scopus 로고
    • Fish oil supplementation in the treatment of major depression: a randomised double-blind placebo-controlled trial
    • Grenyer B.F.S., et al. Fish oil supplementation in the treatment of major depression: a randomised double-blind placebo-controlled trial. Prog. Neuropsychopharmacol. Biol. Psychiatry 2007, 31:1393-1396.
    • (2007) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.31 , pp. 1393-1396
    • Grenyer, B.F.S.1
  • 77
    • 0001398513 scopus 로고    scopus 로고
    • Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance
    • Hahm S., et al. Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance. Neuron 1999, 23:537-548.
    • (1999) Neuron , vol.23 , pp. 537-548
    • Hahm, S.1
  • 78
    • 1542283786 scopus 로고    scopus 로고
    • Is low dietary intake of omega-3 fatty acids associated with depression?
    • Hakkarainen R., et al. Is low dietary intake of omega-3 fatty acids associated with depression?. Am. J. Psychiatry 2004, 161:567-569.
    • (2004) Am. J. Psychiatry , vol.161 , pp. 567-569
    • Hakkarainen, R.1
  • 79
    • 0043135252 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance
    • Hariri A.R., et al. Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance. J. Neurosci. 2003, 23:6690-6694.
    • (2003) J. Neurosci. , vol.23 , pp. 6690-6694
    • Hariri, A.R.1
  • 80
    • 84856181467 scopus 로고    scopus 로고
    • Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics
    • Heim C., Binder E.B. Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics. Exp. Neurol. 2011, 233:102-111.
    • (2011) Exp. Neurol. , vol.233 , pp. 102-111
    • Heim, C.1    Binder, E.B.2
  • 81
    • 0032730256 scopus 로고    scopus 로고
    • The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders
    • Heim C., Nemeroff C.B. The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders. Biol. Psychiatry 1999, 46:1509-1522.
    • (1999) Biol. Psychiatry , vol.46 , pp. 1509-1522
    • Heim, C.1    Nemeroff, C.B.2
  • 82
    • 0035875146 scopus 로고    scopus 로고
    • The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies
    • Heim C., Nemeroff C.B. The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biol. Psychiatry 2001, 49:1023-1039.
    • (2001) Biol. Psychiatry , vol.49 , pp. 1023-1039
    • Heim, C.1    Nemeroff, C.B.2
  • 83
    • 17144409702 scopus 로고    scopus 로고
    • Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk-1 protein expression
    • Heine V.M., et al. Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk-1 protein expression. Eur. J. Neurosci. 2005, 21:1304-1314.
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 1304-1314
    • Heine, V.M.1
  • 84
    • 84856167119 scopus 로고    scopus 로고
    • Effect of exercise training on depressive symptoms among patients with a chronic illness: a systematic review and meta-analysis of randomized controlled trials
    • Herring M.P., et al. Effect of exercise training on depressive symptoms among patients with a chronic illness: a systematic review and meta-analysis of randomized controlled trials. Arch. Intern. Med. 2012, 172:101-111.
    • (2012) Arch. Intern. Med. , vol.172 , pp. 101-111
    • Herring, M.P.1
  • 85
    • 0032542958 scopus 로고    scopus 로고
    • Fish consumption and major depression
    • Hibbeln J.R. Fish consumption and major depression. Lancet 1998, 351:1213.
    • (1998) Lancet , vol.351 , pp. 1213
    • Hibbeln, J.R.1
  • 86
    • 77950113882 scopus 로고    scopus 로고
    • Endogenous cannabinoid signaling is required for voluntary exercise-induced enhancement of progenitor cell proliferation in the hippocampus
    • Hill M.N., et al. Endogenous cannabinoid signaling is required for voluntary exercise-induced enhancement of progenitor cell proliferation in the hippocampus. Hippocampus 2010, 20:513-523.
    • (2010) Hippocampus , vol.20 , pp. 513-523
    • Hill, M.N.1
  • 87
    • 75749114797 scopus 로고    scopus 로고
    • MTOR signaling: at the crossroads of plasticity, memory and disease
    • Hoeffer C.A., Klann E. mTOR signaling: at the crossroads of plasticity, memory and disease. Trends Neurosci. 2010, 33:67-75.
    • (2010) Trends Neurosci. , vol.33 , pp. 67-75
    • Hoeffer, C.A.1    Klann, E.2
  • 88
    • 35248892522 scopus 로고    scopus 로고
    • Omega-3 fatty acids on the forced-swimming test
    • Huang S.-Y., et al. Omega-3 fatty acids on the forced-swimming test. J. Psychiatr. Res. 2008, 42:58-63.
    • (2008) J. Psychiatr. Res. , vol.42 , pp. 58-63
    • Huang, S.-Y.1
  • 89
    • 78149495829 scopus 로고    scopus 로고
    • Maternal separation decreases adult hippocampal cell proliferation and impairs cognitive performance but has little effect on stress sensitivity and anxiety in adult Wistar rats
    • Hulshof H.J., et al. Maternal separation decreases adult hippocampal cell proliferation and impairs cognitive performance but has little effect on stress sensitivity and anxiety in adult Wistar rats. Behav. Brain Res. 2011, 216:552-560.
    • (2011) Behav. Brain Res. , vol.216 , pp. 552-560
    • Hulshof, H.J.1
  • 90
    • 36849092030 scopus 로고    scopus 로고
    • Antidepressant actions of the exercise-regulated gene VGF
    • Hunsberger J.G., et al. Antidepressant actions of the exercise-regulated gene VGF. Nat. Med. 2007, 13:1476-1482.
    • (2007) Nat. Med. , vol.13 , pp. 1476-1482
    • Hunsberger, J.G.1
  • 91
    • 0027636244 scopus 로고
    • Techniques for establishing schedules with wheel running as reinforcement in rats
    • Iversen I.H. Techniques for establishing schedules with wheel running as reinforcement in rats. J. Exp. Anal. Behav. 1993, 60:219-238.
    • (1993) J. Exp. Anal. Behav. , vol.60 , pp. 219-238
    • Iversen, I.H.1
  • 92
    • 33744991083 scopus 로고    scopus 로고
    • Brief uncontrollable stress causes dendritic retraction in infralimbic cortex and resistance to fear extinction in mice
    • Izquierdo A., et al. Brief uncontrollable stress causes dendritic retraction in infralimbic cortex and resistance to fear extinction in mice. J. Neurosci. 2006, 26:5733-5738.
    • (2006) J. Neurosci. , vol.26 , pp. 5733-5738
    • Izquierdo, A.1
  • 93
    • 34247857349 scopus 로고    scopus 로고
    • Chronic food restriction in young rats results in depression- and anxiety-like behaviors with decreased expression of serotonin reuptake transporter
    • Jahng J.W., et al. Chronic food restriction in young rats results in depression- and anxiety-like behaviors with decreased expression of serotonin reuptake transporter. Brain Res. 2007, 1150:100-107.
    • (2007) Brain Res. , vol.1150 , pp. 100-107
    • Jahng, J.W.1
  • 94
    • 0030785531 scopus 로고    scopus 로고
    • Dietary n-3 fatty acids and therapy for rheumatoid arthritis
    • James M.J., Cleland L.G. Dietary n-3 fatty acids and therapy for rheumatoid arthritis. Semin. Arthritis Rheum. 1997, 27:85-97.
    • (1997) Semin. Arthritis Rheum. , vol.27 , pp. 85-97
    • James, M.J.1    Cleland, L.G.2
  • 95
    • 79961129428 scopus 로고    scopus 로고
    • The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder
    • Jernigan C.S., et al. The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder. Prog. Neuropsychopharmacol. Biol. Psychiatry 2011, 35:1774-1779.
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , pp. 1774-1779
    • Jernigan, C.S.1
  • 96
    • 63049099414 scopus 로고    scopus 로고
    • BDNF mediates the neuroprotective effects of positive AMPA receptor modulators against MPP+-induced toxicity in cultured hippocampal and mesencephalic slices
    • Jourdi H., et al. BDNF mediates the neuroprotective effects of positive AMPA receptor modulators against MPP+-induced toxicity in cultured hippocampal and mesencephalic slices. Neuropharmacology 2009, 56:876-885.
    • (2009) Neuropharmacology , vol.56 , pp. 876-885
    • Jourdi, H.1
  • 97
    • 18144416532 scopus 로고    scopus 로고
    • Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity
    • Karege F., et al. Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity. Biol. Psychiatry 2005, 57:1068-1072.
    • (2005) Biol. Psychiatry , vol.57 , pp. 1068-1072
    • Karege, F.1
  • 98
    • 10344238087 scopus 로고    scopus 로고
    • Social supports and serotonin transporter gene moderate depression in maltreated children
    • Kaufman J., et al. Social supports and serotonin transporter gene moderate depression in maltreated children. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:17316-17321.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 17316-17321
    • Kaufman, J.1
  • 99
    • 33645337891 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children
    • Kaufman J., et al. Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. Biol. Psychiatry 2006, 59:673-680.
    • (2006) Biol. Psychiatry , vol.59 , pp. 673-680
    • Kaufman, J.1
  • 100
    • 21344449777 scopus 로고    scopus 로고
    • "A gene for. .": the nature of gene action in psychiatric disorders
    • Kendler K.S. "A gene for. .": the nature of gene action in psychiatric disorders. Am. J. Psychiatry 2005, 162:1243-1252.
    • (2005) Am. J. Psychiatry , vol.162 , pp. 1243-1252
    • Kendler, K.S.1
  • 101
    • 20344374645 scopus 로고    scopus 로고
    • Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication
    • Kessler R.C., et al. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch. Gen. Psychiatry 2005, 62:617-627.
    • (2005) Arch. Gen. Psychiatry , vol.62 , pp. 617-627
    • Kessler, R.C.1
  • 102
    • 84862824404 scopus 로고    scopus 로고
    • Regular exercise cures depression-like behavior via VEGF-Flk-1 signaling in chronically stressed mice
    • Kiuchi T., et al. Regular exercise cures depression-like behavior via VEGF-Flk-1 signaling in chronically stressed mice. Neuroscience 2012, 207:208-217.
    • (2012) Neuroscience , vol.207 , pp. 208-217
    • Kiuchi, T.1
  • 103
    • 79956017788 scopus 로고    scopus 로고
    • Blood BDNF concentrations reflect brain-tissue BDNF levels across species
    • Klein A.B., et al. Blood BDNF concentrations reflect brain-tissue BDNF levels across species. Int. J. Neuropsychopharmacol. 2011, 14:347-353.
    • (2011) Int. J. Neuropsychopharmacol. , vol.14 , pp. 347-353
    • Klein, A.B.1
  • 104
    • 80053601060 scopus 로고    scopus 로고
    • Involvement of the mammalian target of rapamycin signaling in the antidepressant-like effect of group II metabotropic glutamate receptor antagonists
    • Koike H., et al. Involvement of the mammalian target of rapamycin signaling in the antidepressant-like effect of group II metabotropic glutamate receptor antagonists. Neuropharmacology 2011, 61:1419-1423.
    • (2011) Neuropharmacology , vol.61 , pp. 1419-1423
    • Koike, H.1
  • 105
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan V., Nestler E.J. The molecular neurobiology of depression. Nature 2008, 455:894-902.
    • (2008) Nature , vol.455 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 106
    • 84873483502 scopus 로고    scopus 로고
    • Exercise can rescue recognition memory impairment in a model with reduced adult hippocampal neurogenesis
    • Lafenêtre P., et al. Exercise can rescue recognition memory impairment in a model with reduced adult hippocampal neurogenesis. Front. Behav. Neurosci. 2010, 3:34.
    • (2010) Front. Behav. Neurosci. , vol.3 , pp. 34
    • Lafenêtre, P.1
  • 107
    • 0041903805 scopus 로고    scopus 로고
    • VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
    • Lambrechts D., et al. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat. Genet. 2003, 34:383-394.
    • (2003) Nat. Genet. , vol.34 , pp. 383-394
    • Lambrechts, D.1
  • 108
    • 0036734833 scopus 로고    scopus 로고
    • Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice
    • Lee J., et al. Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J. Neurochem. 2002, 82:1367-1375.
    • (2002) J. Neurochem. , vol.82 , pp. 1367-1375
    • Lee, J.1
  • 109
    • 0036488190 scopus 로고    scopus 로고
    • Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice
    • Lee J., et al. Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice. J. Neurochem. 2002, 80:539-547.
    • (2002) J. Neurochem. , vol.80 , pp. 539-547
    • Lee, J.1
  • 110
    • 34247574704 scopus 로고    scopus 로고
    • Depressive behaviors and decreased expression of serotonin reuptake transporter in rats that experienced neonatal maternal separation
    • Lee J.-H., et al. Depressive behaviors and decreased expression of serotonin reuptake transporter in rats that experienced neonatal maternal separation. Neurosci. Res. 2007, 58:32-39.
    • (2007) Neurosci. Res. , vol.58 , pp. 32-39
    • Lee, J.-H.1
  • 111
    • 80052433479 scopus 로고    scopus 로고
    • The efficacy of omega-3 supplementation for major depression: a randomized controlled trial
    • Lespérance F., et al. The efficacy of omega-3 supplementation for major depression: a randomized controlled trial. J. Clin. Psychiatry 2011, 72:1054-1062.
    • (2011) J. Clin. Psychiatry , vol.72 , pp. 1054-1062
    • Lespérance, F.1
  • 112
    • 48749115329 scopus 로고    scopus 로고
    • TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment
    • Li Y., et al. TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment. Neuron 2008, 59:399-412.
    • (2008) Neuron , vol.59 , pp. 399-412
    • Li, Y.1
  • 113
    • 77955909841 scopus 로고    scopus 로고
    • MTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists
    • Li N., et al. mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science 2010, 329:959-964.
    • (2010) Science , vol.329 , pp. 959-964
    • Li, N.1
  • 114
    • 79953166373 scopus 로고    scopus 로고
    • Glutamate N-methyl-d-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure
    • Li N., et al. Glutamate N-methyl-d-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. Biol. Psychiatry 2011, 69:754-761.
    • (2011) Biol. Psychiatry , vol.69 , pp. 754-761
    • Li, N.1
  • 115
    • 34249314353 scopus 로고    scopus 로고
    • Intravenous ketamine therapy in a patient with a treatment-resistant major depression
    • Liebrenz M., et al. Intravenous ketamine therapy in a patient with a treatment-resistant major depression. Swiss Med. Wkly. 2007, 137:234-236.
    • (2007) Swiss Med. Wkly. , vol.137 , pp. 234-236
    • Liebrenz, M.1
  • 116
    • 0033926720 scopus 로고    scopus 로고
    • Maternal care, hippocampal synaptogenesis and cognitive development in rats
    • Liu D., et al. Maternal care, hippocampal synaptogenesis and cognitive development in rats. Nat. Neurosci. 2000, 3:799-806.
    • (2000) Nat. Neurosci. , vol.3 , pp. 799-806
    • Liu, D.1
  • 117
    • 84857083262 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex
    • Liu R.-J., et al. Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex. Biol. Psychiatry 2011, 71:996-1005.
    • (2011) Biol. Psychiatry , vol.71 , pp. 996-1005
    • Liu, R.-J.1
  • 118
    • 77952547357 scopus 로고    scopus 로고
    • Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour
    • Llorens-Martín M., et al. Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour. Mol. Cell. Neurosci. 2010, 44:109-117.
    • (2010) Mol. Cell. Neurosci. , vol.44 , pp. 109-117
    • Llorens-Martín, M.1
  • 119
    • 79951906240 scopus 로고    scopus 로고
    • Effect of brain-derived neurotrophic factor haploinsufficiency on stress-induced remodeling of hippocampal neurons
    • Magariños A.M., et al. Effect of brain-derived neurotrophic factor haploinsufficiency on stress-induced remodeling of hippocampal neurons. Hippocampus 2011, 21:253-264.
    • (2011) Hippocampus , vol.21 , pp. 253-264
    • Magariños, A.M.1
  • 120
    • 19844365569 scopus 로고    scopus 로고
    • Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor
    • Maier S.F., Watkins L.R. Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor. Neurosci. Biobehav. Rev. 2005, 29:829-841.
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , pp. 829-841
    • Maier, S.F.1    Watkins, L.R.2
  • 121
    • 0037411534 scopus 로고    scopus 로고
    • Voluntary wheel running modulates glutamate receptor subunit gene expression and stress hormone release in Lewis rats
    • Makatsori A., et al. Voluntary wheel running modulates glutamate receptor subunit gene expression and stress hormone release in Lewis rats. Psychoneuroendocrinology 2003, 28:702-714.
    • (2003) Psychoneuroendocrinology , vol.28 , pp. 702-714
    • Makatsori, A.1
  • 122
    • 0037844785 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression
    • Marangell L.B., et al. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am. J. Psychiatry 2003, 160:996-998.
    • (2003) Am. J. Psychiatry , vol.160 , pp. 996-998
    • Marangell, L.B.1
  • 123
    • 34548336779 scopus 로고    scopus 로고
    • New insights into BDNF function in depression and anxiety
    • Martinowich K., et al. New insights into BDNF function in depression and anxiety. Nat. Neurosci. 2007, 10:1089-1093.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1089-1093
    • Martinowich, K.1
  • 124
    • 77954947300 scopus 로고    scopus 로고
    • EPA but not DHA appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: evidence from a meta-analysis of randomized controlled trials
    • Martins J.G. EPA but not DHA appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: evidence from a meta-analysis of randomized controlled trials. J. Am. Coll. Nutr. 2009, 28:525-542.
    • (2009) J. Am. Coll. Nutr. , vol.28 , pp. 525-542
    • Martins, J.G.1
  • 125
    • 23944468510 scopus 로고    scopus 로고
    • Energy intake, meal frequency, and health: a neurobiological perspective
    • Mattson M.P. Energy intake, meal frequency, and health: a neurobiological perspective. Annu. Rev. Nutr. 2005, 25:237-260.
    • (2005) Annu. Rev. Nutr. , vol.25 , pp. 237-260
    • Mattson, M.P.1
  • 126
    • 4544328810 scopus 로고    scopus 로고
    • BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders
    • Mattson M.P., et al. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. Trends Neurosci. 2004, 27:589-594.
    • (2004) Trends Neurosci. , vol.27 , pp. 589-594
    • Mattson, M.P.1
  • 127
    • 8444250215 scopus 로고    scopus 로고
    • A neural signaling triumvirate that influences ageing and age-related disease: insulin/IGF-1, BDNF and serotonin
    • Mattson M.P., et al. A neural signaling triumvirate that influences ageing and age-related disease: insulin/IGF-1, BDNF and serotonin. Ageing Res. Rev. 2004, 3:445-464.
    • (2004) Ageing Res. Rev. , vol.3 , pp. 445-464
    • Mattson, M.P.1
  • 128
    • 0037079064 scopus 로고    scopus 로고
    • Spatially restricted actions of BDNF
    • McAllister A.K. Spatially restricted actions of BDNF. Neuron 2002, 36:549-550.
    • (2002) Neuron , vol.36 , pp. 549-550
    • McAllister, A.K.1
  • 129
    • 0032912252 scopus 로고    scopus 로고
    • Stress and hippocampal plasticity
    • McEwen B.S. Stress and hippocampal plasticity. Annu. Rev. Neurosci. 1999, 22:105-122.
    • (1999) Annu. Rev. Neurosci. , vol.22 , pp. 105-122
    • McEwen, B.S.1
  • 130
    • 34447629382 scopus 로고    scopus 로고
    • Physiology and neurobiology of stress and adaptation: central role of the brain
    • McEwen B.S. Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol. Rev. 2007, 87:873-904.
    • (2007) Physiol. Rev. , vol.87 , pp. 873-904
    • McEwen, B.S.1
  • 131
    • 61949248898 scopus 로고    scopus 로고
    • A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder
    • McKinnon M.C., et al. A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder. J. Psychiatry Neurosci. 2009, 34:41-54.
    • (2009) J. Psychiatry Neurosci. , vol.34 , pp. 41-54
    • McKinnon, M.C.1
  • 132
    • 0034928759 scopus 로고    scopus 로고
    • Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations
    • Meaney M.J. Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annu. Rev. Neurosci. 2001, 24:1161-1192.
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 1161-1192
    • Meaney, M.J.1
  • 133
    • 3343008569 scopus 로고    scopus 로고
    • Early life experience alters response of adult neurogenesis to stress
    • Mirescu C., et al. Early life experience alters response of adult neurogenesis to stress. Nat. Neurosci. 2004, 7:841-846.
    • (2004) Nat. Neurosci. , vol.7 , pp. 841-846
    • Mirescu, C.1
  • 134
    • 0034521499 scopus 로고    scopus 로고
    • Docosahexanoic acid and omega-3 fatty acids in depression
    • Mischoulon D., Fava M. Docosahexanoic acid and omega-3 fatty acids in depression. Psychiatr. Clin. North Am. 2000, 23:785-794.
    • (2000) Psychiatr. Clin. North Am. , vol.23 , pp. 785-794
    • Mischoulon, D.1    Fava, M.2
  • 135
    • 0030900732 scopus 로고    scopus 로고
    • Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
    • Moghaddam B., et al. Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J. Neurosci. 1997, 17:2921-2927.
    • (1997) J. Neurosci. , vol.17 , pp. 2921-2927
    • Moghaddam, B.1
  • 136
    • 38449090175 scopus 로고    scopus 로고
    • Elucidating the role of brain-derived neurotrophic factor in the brain
    • Monteggia L.M. Elucidating the role of brain-derived neurotrophic factor in the brain. Am. J. Psychiatry 2007, 164:1790.
    • (2007) Am. J. Psychiatry , vol.164 , pp. 1790
    • Monteggia, L.M.1
  • 137
    • 3242666768 scopus 로고    scopus 로고
    • Essential role of brain-derived neurotrophic factor in adult hippocampal function
    • Monteggia L.M., et al. Essential role of brain-derived neurotrophic factor in adult hippocampal function. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:10827-10832.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 10827-10832
    • Monteggia, L.M.1
  • 138
    • 0030064218 scopus 로고    scopus 로고
    • The long-term impact of the physical, emotional, and sexual abuse of children: a community study
    • Mullen P.E., et al. The long-term impact of the physical, emotional, and sexual abuse of children: a community study. Child Abuse Negl. 1996, 20:7-21.
    • (1996) Child Abuse Negl. , vol.20 , pp. 7-21
    • Mullen, P.E.1
  • 139
    • 24044539823 scopus 로고    scopus 로고
    • Chronic stress, as well as acute stress, reduces BDNF mRNA expression in the rat hippocampus but less robustly
    • Murakami S., et al. Chronic stress, as well as acute stress, reduces BDNF mRNA expression in the rat hippocampus but less robustly. Neurosci. Res. 2005, 53:129-139.
    • (2005) Neurosci. Res. , vol.53 , pp. 129-139
    • Murakami, S.1
  • 140
    • 3242723174 scopus 로고    scopus 로고
    • Effects of fish oil on the central nervous system: a new potential antidepressant?
    • Naliwaiko K., et al. Effects of fish oil on the central nervous system: a new potential antidepressant?. Nutr. Neurosci. 2004, 7:91-99.
    • (2004) Nutr. Neurosci. , vol.7 , pp. 91-99
    • Naliwaiko, K.1
  • 141
    • 77954214296 scopus 로고    scopus 로고
    • Interaction between childhood adversity, brain-derived neurotrophic factor val/met and serotonin transporter promoter polymorphism on depression: the TRAILS study
    • Nederhof E., et al. Interaction between childhood adversity, brain-derived neurotrophic factor val/met and serotonin transporter promoter polymorphism on depression: the TRAILS study. Biol. Psychiatry 2010, 68:209-212.
    • (2010) Biol. Psychiatry , vol.68 , pp. 209-212
    • Nederhof, E.1
  • 142
    • 0036190807 scopus 로고    scopus 로고
    • Addition of omega-3 fatty acid to maintenance medication treatment for recurrent unipolar depressive disorder
    • Nemets B., et al. Addition of omega-3 fatty acid to maintenance medication treatment for recurrent unipolar depressive disorder. Am. J. Psychiatry 2002, 159:477-479.
    • (2002) Am. J. Psychiatry , vol.159 , pp. 477-479
    • Nemets, B.1
  • 143
    • 0037106975 scopus 로고    scopus 로고
    • Preclinical models: status of basic research in depression
    • Nestler E.J., et al. Preclinical models: status of basic research in depression. Biol. Psychiatry 2002, 52:503-528.
    • (2002) Biol. Psychiatry , vol.52 , pp. 503-528
    • Nestler, E.J.1
  • 144
    • 0028815653 scopus 로고
    • Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
    • Nibuya M., et al. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J. Neurosci. 1995, 15:7539-7547.
    • (1995) J. Neurosci. , vol.15 , pp. 7539-7547
    • Nibuya, M.1
  • 145
    • 0029992189 scopus 로고    scopus 로고
    • Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus
    • Nibuya M., et al. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. J. Neurosci. 1996, 16:2365-2372.
    • (1996) J. Neurosci. , vol.16 , pp. 2365-2372
    • Nibuya, M.1
  • 146
    • 8544249878 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology
    • Pezawas L., et al. The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology. J. Neurosci. 2004, 24:10099-10102.
    • (2004) J. Neurosci. , vol.24 , pp. 10099-10102
    • Pezawas, L.1
  • 147
    • 1642421311 scopus 로고    scopus 로고
    • Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex
    • Radley J.J., et al. Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex. Neuroscience 2004, 125:1-6.
    • (2004) Neuroscience , vol.125 , pp. 1-6
    • Radley, J.J.1
  • 148
    • 32144436554 scopus 로고    scopus 로고
    • Repeated stress induces dendritic spine loss in the rat medial prefrontal cortex
    • Radley J.J., et al. Repeated stress induces dendritic spine loss in the rat medial prefrontal cortex. Cereb. Cortex 2006, 16:313-320.
    • (2006) Cereb. Cortex , vol.16 , pp. 313-320
    • Radley, J.J.1
  • 149
    • 0033135401 scopus 로고    scopus 로고
    • Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression
    • Rajkowska G., et al. Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression. Biol. Psychiatry 1999, 45:1085-1098.
    • (1999) Biol. Psychiatry , vol.45 , pp. 1085-1098
    • Rajkowska, G.1
  • 150
    • 33845775752 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism
    • Rao J.S., et al. n-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism. Mol. Psychiatry 2007, 12:36-46.
    • (2007) Mol. Psychiatry , vol.12 , pp. 36-46
    • Rao, J.S.1
  • 151
    • 31144475277 scopus 로고    scopus 로고
    • Exercise-induced changes in dendritic structure and complexity in the adult hippocampal dentate gyrus
    • Redila V.A., Christie B.R. Exercise-induced changes in dendritic structure and complexity in the adult hippocampal dentate gyrus. Neuroscience 2006, 137:1299-1307.
    • (2006) Neuroscience , vol.137 , pp. 1299-1307
    • Redila, V.A.1    Christie, B.R.2
  • 152
    • 39049120230 scopus 로고    scopus 로고
    • Omega-3 fatty acids as a treatment for perinatal depression: randomized double-blind placebo-controlled trial
    • Rees A.-M., et al. Omega-3 fatty acids as a treatment for perinatal depression: randomized double-blind placebo-controlled trial. Aust. N. Z. J. Psychiatry 2008, 42:199-205.
    • (2008) Aust. N. Z. J. Psychiatry , vol.42 , pp. 199-205
    • Rees, A.-M.1
  • 153
    • 67649206975 scopus 로고    scopus 로고
    • Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis
    • Risch N., et al. Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA 2009, 301:2462-2471.
    • (2009) JAMA , vol.301 , pp. 2462-2471
    • Risch, N.1
  • 154
    • 1642412555 scopus 로고    scopus 로고
    • Postnatal repeated maternal deprivation produces age-dependent changes of brain-derived neurotrophic factor expression in selected rat brain regions
    • Roceri M., et al. Postnatal repeated maternal deprivation produces age-dependent changes of brain-derived neurotrophic factor expression in selected rat brain regions. Biol. Psychiatry 2004, 55:708-714.
    • (2004) Biol. Psychiatry , vol.55 , pp. 708-714
    • Roceri, M.1
  • 155
    • 77954191126 scopus 로고    scopus 로고
    • What is the effectiveness of the use of polyunsaturated fatty acid omega-3 in the treatment of depression?
    • Rocha Araujo D.M., et al. What is the effectiveness of the use of polyunsaturated fatty acid omega-3 in the treatment of depression?. Expert Rev. Neurother. 2010, 10:1117-1129.
    • (2010) Expert Rev. Neurother. , vol.10 , pp. 1117-1129
    • Rocha Araujo, D.M.1
  • 156
    • 67349174522 scopus 로고    scopus 로고
    • Stress, memory and the amygdala
    • Roozendaal B., et al. Stress, memory and the amygdala. Nat. Rev. Neurosci. 2009, 10:423-433.
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 423-433
    • Roozendaal, B.1
  • 157
    • 0033937640 scopus 로고    scopus 로고
    • Effects of reduced energy intake on the biology of aging: the primate model
    • Roth G.S., et al. Effects of reduced energy intake on the biology of aging: the primate model. Eur. J. Clin. Nutr. 2000, 54(Suppl. 3):S15-S20.
    • (2000) Eur. J. Clin. Nutr. , vol.54 , Issue.SUPPL. 3
    • Roth, G.S.1
  • 158
    • 0032863708 scopus 로고    scopus 로고
    • Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression
    • Russo-Neustadt A., et al. Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression. Neuropsychopharmacology 1999, 21:679-682.
    • (1999) Neuropsychopharmacology , vol.21 , pp. 679-682
    • Russo-Neustadt, A.1
  • 159
    • 0034619534 scopus 로고    scopus 로고
    • Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus
    • Russo-Neustadt A.A., et al. Physical activity and antidepressant treatment potentiate the expression of specific brain-derived neurotrophic factor transcripts in the rat hippocampus. Neuroscience 2000, 101:305-312.
    • (2000) Neuroscience , vol.101 , pp. 305-312
    • Russo-Neustadt, A.A.1
  • 160
    • 84862216979 scopus 로고    scopus 로고
    • Mapping the depressed brain: a meta-analysis of structural and functional alterations in major depressive disorder
    • Sacher J., et al. Mapping the depressed brain: a meta-analysis of structural and functional alterations in major depressive disorder. J. Affect. Disord. 2011, 140:142-148.
    • (2011) J. Affect. Disord. , vol.140 , pp. 142-148
    • Sacher, J.1
  • 161
    • 34548348778 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis in depression
    • Sahay A., Hen R. Adult hippocampal neurogenesis in depression. Nat. Neurosci. 2007, 10:1110-1115.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1110-1115
    • Sahay, A.1    Hen, R.2
  • 162
    • 13944257674 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus
    • Sairanen M., et al. Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus. J. Neurosci. 2005, 25:1089-1094.
    • (2005) J. Neurosci. , vol.25 , pp. 1089-1094
    • Sairanen, M.1
  • 163
    • 79952610907 scopus 로고    scopus 로고
    • Neurogenesis and affective disorders
    • Samuels B.A., Hen R. Neurogenesis and affective disorders. Eur. J. Neurosci. 2011, 33:1152-1159.
    • (2011) Eur. J. Neurosci. , vol.33 , pp. 1152-1159
    • Samuels, B.A.1    Hen, R.2
  • 164
    • 75849155175 scopus 로고    scopus 로고
    • Cortical inhibition, gamma-aminobutyric acid, and major depression: there is plenty of smoke but is there fire?
    • Sanacora G. Cortical inhibition, gamma-aminobutyric acid, and major depression: there is plenty of smoke but is there fire?. Biol. Psychiatry 2010, 67:397-398.
    • (2010) Biol. Psychiatry , vol.67 , pp. 397-398
    • Sanacora, G.1
  • 165
    • 0042528720 scopus 로고    scopus 로고
    • Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
    • Santarelli L., et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 2003, 301:805-809.
    • (2003) Science , vol.301 , pp. 805-809
    • Santarelli, L.1
  • 166
    • 79953219030 scopus 로고    scopus 로고
    • The antidepressive effect of the physical exercise correlates with increased levels of mature BDNF, and proBDNF proteolytic cleavage-related genes, p11 and tPA
    • Sartori C.R., et al. The antidepressive effect of the physical exercise correlates with increased levels of mature BDNF, and proBDNF proteolytic cleavage-related genes, p11 and tPA. Neuroscience 2011, 180:9-18.
    • (2011) Neuroscience , vol.180 , pp. 9-18
    • Sartori, C.R.1
  • 167
    • 77958021917 scopus 로고    scopus 로고
    • Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models
    • Schmidt H.D., Duman R.S. Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models. Neuropsychopharmacology 2010, 35:2378-2391.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2378-2391
    • Schmidt, H.D.1    Duman, R.S.2
  • 168
    • 80054756091 scopus 로고    scopus 로고
    • Functional biomarkers of depression: diagnosis, treatment, and pathophysiology
    • Schmidt H.D., et al. Functional biomarkers of depression: diagnosis, treatment, and pathophysiology. Neuropsychopharmacology 2011, 36:2375-2394.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2375-2394
    • Schmidt, H.D.1
  • 170
    • 0002210727 scopus 로고
    • A syndrome produced by diverse nocuous agents
    • Selye H. A syndrome produced by diverse nocuous agents. Nature 1936, 138.
    • (1936) Nature , vol.138
    • Selye, H.1
  • 171
    • 49749101642 scopus 로고    scopus 로고
    • Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications
    • Sen S., et al. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biol. Psychiatry 2008, 64:527-532.
    • (2008) Biol. Psychiatry , vol.64 , pp. 527-532
    • Sen, S.1
  • 172
    • 66249120082 scopus 로고    scopus 로고
    • Stress-induced dendritic remodeling in the prefrontal cortex is circuit specific
    • Shansky R.M., et al. Stress-induced dendritic remodeling in the prefrontal cortex is circuit specific. Cereb. Cortex 2009, 19:2479-2484.
    • (2009) Cereb. Cortex , vol.19 , pp. 2479-2484
    • Shansky, R.M.1
  • 173
    • 0029862949 scopus 로고    scopus 로고
    • Hippocampal atrophy in recurrent major depression
    • Sheline Y.I., et al. Hippocampal atrophy in recurrent major depression. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:3908-3913.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 3908-3913
    • Sheline, Y.I.1
  • 174
    • 0041880262 scopus 로고    scopus 로고
    • Untreated depression and hippocampal volume loss
    • Sheline Y.I., et al. Untreated depression and hippocampal volume loss. Am. J. Psychiatry 2003, 160:1516-1518.
    • (2003) Am. J. Psychiatry , vol.160 , pp. 1516-1518
    • Sheline, Y.I.1
  • 175
    • 0038771149 scopus 로고    scopus 로고
    • Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants
    • Shimizu E., et al. Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol. Psychiatry 2003, 54:70-75.
    • (2003) Biol. Psychiatry , vol.54 , pp. 70-75
    • Shimizu, E.1
  • 176
    • 0037092425 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
    • Shirayama Y., et al. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J. Neurosci. 2002, 22:3251-3261.
    • (2002) J. Neurosci. , vol.22 , pp. 3251-3261
    • Shirayama, Y.1
  • 177
    • 0031031001 scopus 로고    scopus 로고
    • Antidepressant-like effect of brain-derived neurotrophic factor (BDNF)
    • Siuciak J.A., et al. Antidepressant-like effect of brain-derived neurotrophic factor (BDNF). Pharmacol. Biochem. Behav. 1997, 56:131-137.
    • (1997) Pharmacol. Biochem. Behav. , vol.56 , pp. 131-137
    • Siuciak, J.A.1
  • 178
    • 67650289960 scopus 로고    scopus 로고
    • BDNF activates mTOR to regulate GluR1 expression required for memory formation
    • Slipczuk L., et al. BDNF activates mTOR to regulate GluR1 expression required for memory formation. PLoS One 2009, 4:e6007.
    • (2009) PLoS One , vol.4
    • Slipczuk, L.1
  • 179
    • 80052050190 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis buffers stress responses and depressive behaviour
    • Snyder J.S., et al. Adult hippocampal neurogenesis buffers stress responses and depressive behaviour. Nature 2011, 476:458-461.
    • (2011) Nature , vol.476 , pp. 458-461
    • Snyder, J.S.1
  • 180
    • 0034104493 scopus 로고    scopus 로고
    • Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement
    • Sousa N., et al. Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement. Neuroscience 2000, 97:253-266.
    • (2000) Neuroscience , vol.97 , pp. 253-266
    • Sousa, N.1
  • 181
    • 84876284334 scopus 로고    scopus 로고
    • Exercise activates the endocannabinoid system
    • Sparling P.B., et al. Exercise activates the endocannabinoid system. Neuroreport 2003, 14:2209-2211.
    • (2003) Neuroreport , vol.14 , pp. 2209-2211
    • Sparling, P.B.1
  • 182
    • 7444239843 scopus 로고    scopus 로고
    • Cellular changes in the postmortem hippocampus in major depression
    • Stockmeier C.A., et al. Cellular changes in the postmortem hippocampus in major depression. Biol. Psychiatry 2004, 56:640-650.
    • (2004) Biol. Psychiatry , vol.56 , pp. 640-650
    • Stockmeier, C.A.1
  • 183
    • 36349012003 scopus 로고    scopus 로고
    • Running induces widespread structural alterations in the hippocampus and entorhinal cortex
    • Stranahan A.M., et al. Running induces widespread structural alterations in the hippocampus and entorhinal cortex. Hippocampus 2007, 17:1017-1022.
    • (2007) Hippocampus , vol.17 , pp. 1017-1022
    • Stranahan, A.M.1
  • 184
    • 52049106816 scopus 로고    scopus 로고
    • Central mechanisms of HPA axis regulation by voluntary exercise
    • Stranahan A.M., et al. Central mechanisms of HPA axis regulation by voluntary exercise. Neuromolecular Med. 2008, 10:118-127.
    • (2008) Neuromolecular Med. , vol.10 , pp. 118-127
    • Stranahan, A.M.1
  • 185
    • 0042850504 scopus 로고    scopus 로고
    • Omega-3 fatty acids in major depressive disorder. A preliminary double-blind, placebo-controlled trial
    • Su K.-P., et al. Omega-3 fatty acids in major depressive disorder. A preliminary double-blind, placebo-controlled trial. Eur. Neuropsychopharmacol. 2003, 13:267-271.
    • (2003) Eur. Neuropsychopharmacol. , vol.13 , pp. 267-271
    • Su, K.-P.1
  • 186
    • 21844458922 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation
    • Szeszko P.R., et al. Brain-derived neurotrophic factor val66met polymorphism and volume of the hippocampal formation. Mol. Psychiatry 2005, 10:631-636.
    • (2005) Mol. Psychiatry , vol.10 , pp. 631-636
    • Szeszko, P.R.1
  • 187
    • 7744224557 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites
    • Takei N., et al. Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites. J. Neurosci. 2004, 24:9760-9769.
    • (2004) J. Neurosci. , vol.24 , pp. 9760-9769
    • Takei, N.1
  • 188
    • 72949096531 scopus 로고    scopus 로고
    • Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis
    • Taliaz D., et al. Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis. Mol. Psychiatry 2010, 15:80-92.
    • (2010) Mol. Psychiatry , vol.15 , pp. 80-92
    • Taliaz, D.1
  • 189
    • 74449090471 scopus 로고    scopus 로고
    • Exercise-induced VEGF transcriptional activation in brain, lung and skeletal muscle
    • Tang K., et al. Exercise-induced VEGF transcriptional activation in brain, lung and skeletal muscle. Respir. Physiol. Neurobiol. 2010, 170:16-22.
    • (2010) Respir. Physiol. Neurobiol. , vol.170 , pp. 16-22
    • Tang, K.1
  • 190
    • 36048960698 scopus 로고    scopus 로고
    • The neuropeptide VGF produces antidepressant-like behavioral effects and enhances proliferation in the hippocampus
    • Thakker-Varia S., et al. The neuropeptide VGF produces antidepressant-like behavioral effects and enhances proliferation in the hippocampus. J. Neurosci. 2007, 27:12156-12167.
    • (2007) J. Neurosci. , vol.27 , pp. 12156-12167
    • Thakker-Varia, S.1
  • 191
    • 0035283153 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus
    • Trejo J.L., et al. Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus. J. Neurosci. 2001, 21:1628-1634.
    • (2001) J. Neurosci. , vol.21 , pp. 1628-1634
    • Trejo, J.L.1
  • 192
    • 38649115676 scopus 로고    scopus 로고
    • The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis
    • Trejo J.L., et al. The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis. Mol. Cell. Neurosci. 2008, 37:402-411.
    • (2008) Mol. Cell. Neurosci. , vol.37 , pp. 402-411
    • Trejo, J.L.1
  • 193
    • 79958049864 scopus 로고    scopus 로고
    • Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results
    • Uher R., et al. Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results. J. Affect. Disord. 2011, 135:56-65.
    • (2011) J. Affect. Disord. , vol.135 , pp. 56-65
    • Uher, R.1
  • 194
    • 0033360314 scopus 로고    scopus 로고
    • Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
    • van Praag H., et al. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat. Neurosci. 1999, 2:266-270.
    • (1999) Nat. Neurosci. , vol.2 , pp. 266-270
    • van Praag, H.1
  • 195
    • 58249127595 scopus 로고    scopus 로고
    • PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus
    • Venna V.R., et al. PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus. Psychoneuroendocrinology 2009, 34:199-211.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. 199-211
    • Venna, V.R.1
  • 196
    • 77249091890 scopus 로고    scopus 로고
    • Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity
    • Verhagen M., et al. Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity. Mol. Psychiatry 2010, 15:260-271.
    • (2010) Mol. Psychiatry , vol.15 , pp. 260-271
    • Verhagen, M.1
  • 197
    • 0142103727 scopus 로고    scopus 로고
    • Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder
    • Vermetten E., et al. Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder. Biol. Psychiatry 2003, 54:693-702.
    • (2003) Biol. Psychiatry , vol.54 , pp. 693-702
    • Vermetten, E.1
  • 198
    • 77953356310 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) polymorphism is associated with treatment resistant depression
    • Viikki M., et al. Vascular endothelial growth factor (VEGF) polymorphism is associated with treatment resistant depression. Neurosci. Lett. 2010, 477:105-108.
    • (2010) Neurosci. Lett. , vol.477 , pp. 105-108
    • Viikki, M.1
  • 199
    • 80054095577 scopus 로고    scopus 로고
    • The role of 5-HT(1A) receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism
    • Vines A., et al. The role of 5-HT(1A) receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism. Neuropharmacology 2011, 62:184-191.
    • (2011) Neuropharmacology , vol.62 , pp. 184-191
    • Vines, A.1
  • 200
    • 84855974464 scopus 로고    scopus 로고
    • The roles of neurotrophic factor and Wnt signaling in depression
    • Voleti B., Duman R.S. The roles of neurotrophic factor and Wnt signaling in depression. Clin. Pharmacol. Ther. 2011, 91:333-338.
    • (2011) Clin. Pharmacol. Ther. , vol.91 , pp. 333-338
    • Voleti, B.1    Duman, R.S.2
  • 201
    • 34248388548 scopus 로고    scopus 로고
    • VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants
    • Warner-Schmidt J.L., Duman R.S. VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:4647-4652.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 4647-4652
    • Warner-Schmidt, J.L.1    Duman, R.S.2
  • 202
    • 77950945886 scopus 로고    scopus 로고
    • Early life stress increases anxiety-like behavior in Balbc mice despite a compensatory increase in levels of postnatal maternal care
    • Wei L., et al. Early life stress increases anxiety-like behavior in Balbc mice despite a compensatory increase in levels of postnatal maternal care. Horm. Behav. 2010, 57:396-404.
    • (2010) Horm. Behav. , vol.57 , pp. 396-404
    • Wei, L.1
  • 203
    • 0018761281 scopus 로고
    • Influence of controlled dietary restriction on immunologic function and aging
    • Weindruch R.H., et al. Influence of controlled dietary restriction on immunologic function and aging. Fed. Proc. 1979, 38:2007-2016.
    • (1979) Fed. Proc. , vol.38 , pp. 2007-2016
    • Weindruch, R.H.1
  • 204
    • 37849022761 scopus 로고    scopus 로고
    • The BDNF Val(66)Met×5-HTTLPR×child adversity interaction and depressive symptoms: An attempt at replication
    • Wichers M., et al. The BDNF Val(66)Met×5-HTTLPR×child adversity interaction and depressive symptoms: An attempt at replication. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008, 147B:120-123.
    • (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.147 B , pp. 120-123
    • Wichers, M.1
  • 205
    • 80054884485 scopus 로고    scopus 로고
    • Childhood adversity and allostatic overload of the hypothalamic-pituitary-adrenal axis: a vulnerability model for depressive disorders
    • Wilkinson P.O., Goodyer I.M. Childhood adversity and allostatic overload of the hypothalamic-pituitary-adrenal axis: a vulnerability model for depressive disorders. Dev. Psychopathol. 2011, 23:1017-1037.
    • (2011) Dev. Psychopathol. , vol.23 , pp. 1017-1037
    • Wilkinson, P.O.1    Goodyer, I.M.2
  • 206
    • 0031440325 scopus 로고    scopus 로고
    • Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation
    • Willner P. Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation. Psychopharmacology (Berl) 1997, 134:319-329.
    • (1997) Psychopharmacology (Berl) , vol.134 , pp. 319-329
    • Willner, P.1
  • 207
    • 77953565298 scopus 로고    scopus 로고
    • Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis
    • Wolf S.A., et al. Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis. Cell Commun. Signal. 2010, 8:12.
    • (2010) Cell Commun. Signal. , vol.8 , pp. 12
    • Wolf, S.A.1
  • 208
    • 33746896935 scopus 로고    scopus 로고
    • A randomized trial of an N-methyl-d-aspartate antagonist in treatment-resistant major depression
    • Zarate C.A., et al. A randomized trial of an N-methyl-d-aspartate antagonist in treatment-resistant major depression. Arch. Gen. Psychiatry 2006, 63:856-864.
    • (2006) Arch. Gen. Psychiatry , vol.63 , pp. 856-864
    • Zarate, C.A.1
  • 209
    • 30644474606 scopus 로고    scopus 로고
    • Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus
    • Zhao C., et al. Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. J. Neurosci. 2006, 26:3-11.
    • (2006) J. Neurosci. , vol.26 , pp. 3-11
    • Zhao, C.1
  • 210
    • 31444438416 scopus 로고    scopus 로고
    • Beneficial effects of exercise and its molecular mechanisms on depression in rats
    • Zheng H., et al. Beneficial effects of exercise and its molecular mechanisms on depression in rats. Behav. Brain Res. 2006, 168:47-55.
    • (2006) Behav. Brain Res. , vol.168 , pp. 47-55
    • Zheng, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.