Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites

Journal of Neuroscience

Volumn 24, Issue 44, 2004, Pages 9760-9769

  Takei, Nobuyuki ^a   Inamura, Naoko ^a   Kawamura, Mihoko ^a   Namba, Hisaaki ^a   Hara, Kenta ^b,c   Yonezawa, Kazuyoshi ^b,c   Nawa, Hiroyuki ^a  

^a NIIGATA UNIVERSITY   (Japan)

^b KOBE UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

BDNF; Local protein synthesis; mTOR; Neuron; Raptor; Translation; Tuberin

Indexed keywords

BINDING PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; INITIATION FACTOR 4E BINDING PROTEIN; PROTEIN S6; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE; TUBERIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CONTROLLED STUDY; DENDRITE; ENZYME ACTIVATION; ENZYME LOCALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; TRANSLATION INITIATION; TRANSLATION REGULATION; UPREGULATION;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; CEREBRAL CORTEX; DENDRITES; GENE EXPRESSION REGULATION; MONOMERIC GTP-BINDING PROTEINS; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NEUROPEPTIDES; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; RATS; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; SIROLIMUS; SYNAPTOSOMES; TUMOR SUPPRESSOR PROTEINS;

EID: 7744224557     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1427-04.2004     Document Type: Article

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