메뉴 건너뛰기




Volumn 11, Issue 1, 2006, Pages 86-98

ERK MAP kinase signaling in post-mortem brain of suicide subjects: Differential regulation of upstream Raf kinases Raf-1 and B-Raf

Author keywords

Catalytic activity; Competitive RT PCR; Depression; Hippocampus; Human; Immunolabeling; Prefrontal cortex; Signal transduction

Indexed keywords

B RAF KINASE; CYCLOPHILIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN;

EID: 32844458346     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/sj.mp.4001744     Document Type: Article
Times cited : (111)

References (80)
  • 1
  • 2
    • 0032698075 scopus 로고    scopus 로고
    • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
    • Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 1999; 286: 1358-1362.
    • (1999) Science , vol.286 , pp. 1358-1362
    • Bonni, A.1    Brunet, A.2    West, A.E.3    Datta, S.R.4    Takasu, M.A.5    Greenberg, M.E.6
  • 3
    • 0032861127 scopus 로고    scopus 로고
    • Extracellular-signaling-regulated kinase signaling in neurons
    • Grewal SS, York RD, Stork PJS. Extracellular-signaling-regulated kinase signaling in neurons. Curr Opin Neurobiol 1999; 9: 544-553.
    • (1999) Curr Opin Neurobiol , vol.9 , pp. 544-553
    • Grewal, S.S.1    York, R.D.2    Stork, P.J.S.3
  • 4
    • 0033529638 scopus 로고    scopus 로고
    • Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase
    • Hetman M, Kanning K, Cavanaugh JE, Xia Z. Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. J Biol Chem 1999; 274: 22569-22680.
    • (1999) J Biol Chem , vol.274 , pp. 22569-22680
    • Hetman, M.1    Kanning, K.2    Cavanaugh, J.E.3    Xia, Z.4
  • 5
    • 0033136259 scopus 로고    scopus 로고
    • Making new connections: Role of ERK/MAP kinase signaling in neuronal plasticity
    • Impey S, Obrietan K, Storm DR. Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity. Neuron 1999; 23: 11-14.
    • (1999) Neuron , vol.23 , pp. 11-14
    • Impey, S.1    Obrietan, K.2    Storm, D.R.3
  • 6
    • 2942550646 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in synaptic plasticity and memory
    • Sweatt JD. Mitogen-activated protein kinases in synaptic plasticity and memory. Curr Opin Neurobiol 2004; 14: 311-317.
    • (2004) Curr Opin Neurobiol , vol.14 , pp. 311-317
    • Sweatt, J.D.1
  • 7
    • 0032541671 scopus 로고    scopus 로고
    • Cell cycle targets of Ras/Raf signaling
    • Kerkoff E, Rapp UR. Cell cycle targets of Ras/Raf signaling. Oncogene 1998; 17: 1457-1462.
    • (1998) Oncogene , vol.17 , pp. 1457-1462
    • Kerkoff, E.1    Rapp, U.R.2
  • 8
    • 0028272507 scopus 로고
    • Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
    • Leevers SJ, Paterson HF, Marshall CJ. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 1994; 369: 411-414.
    • (1994) Nature , vol.369 , pp. 411-414
    • Leevers, S.J.1    Paterson, H.F.2    Marshall, C.J.3
  • 9
    • 0025875819 scopus 로고
    • Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases
    • Gomez N, Cohen P. Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases. Nature 1991; 353: 170-173.
    • (1991) Nature , vol.353 , pp. 170-173
    • Gomez, N.1    Cohen, P.2
  • 10
    • 0033937168 scopus 로고    scopus 로고
    • Adult brain neurogenesis and psychiatry: A novel theory of depression
    • Jacobs BL, van Praag H, Gage FH. Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol Psychiatr 2000; 5: 262-269.
    • (2000) Mol Psychiatr , vol.5 , pp. 262-269
    • Jacobs, B.L.1    Van Praag, H.2    Gage, F.H.3
  • 11
    • 0036325686 scopus 로고    scopus 로고
    • Pathophysiology of depression: The concept of synaptic plasticity
    • Duman RS. Pathophysiology of depression: the concept of synaptic plasticity. Eur Psychiatr 2002; 17: 306-310.
    • (2002) Eur Psychiatr , vol.17 , pp. 306-310
    • Duman, R.S.1
  • 12
    • 2442673159 scopus 로고    scopus 로고
    • Life stress, genes, and depression: Multiple pathways lead to increased risk and new opportunities for intervention
    • DOI: 10.1126/stke.225
    • Charney DS, Manji HK. Life stress, genes, and depression: multiple pathways lead to increased risk and new opportunities for intervention. Sci STKE 2004; re5, [DOI: 10.1126/stke.225].
    • (2004) Sci STKE , vol.RE5
    • Charney, D.S.1    Manji, H.K.2
  • 15
    • 0032573166 scopus 로고    scopus 로고
    • Glial reduction in the subgenual prefrontal cortex in mood disorders
    • Ongur D, Drevets WC, Price JL. Glial reduction in the subgenual prefrontal cortex in mood disorders. Proc Natl Acad Sci USA 1998; 95: 13290-13295.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13290-13295
    • Ongur, D.1    Drevets, W.C.2    Price, J.L.3
  • 16
    • 0031590701 scopus 로고    scopus 로고
    • Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients
    • Rajkowska G. Morphometric methods for studying the prefrontal cortex in suicide victims and psychiatric patients. Ann NY Acad Sci USA 1997; 836: 253-268.
    • (1997) Ann NY Acad Sci USA , vol.836 , pp. 253-268
    • Rajkowska, G.1
  • 17
    • 0034667301 scopus 로고    scopus 로고
    • Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells
    • Rajkowska G. Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biol Psychiatr 2000; 48: 766-777.
    • (2000) Biol Psychiatr , vol.48 , pp. 766-777
    • Rajkowska, G.1
  • 18
    • 0024409623 scopus 로고    scopus 로고
    • Hippocampal damage associated with prolonged and fatal stress in primates
    • Uno H, Tarara R, Else JG, Suleman MA, Sapolsky RM. Hippocampal damage associated with prolonged and fatal stress in primates. J Neurosci 1999; 9: 1705-1711.
    • (1999) J Neurosci , vol.9 , pp. 1705-1711
    • Uno, H.1    Tarara, R.2    Else, J.G.3    Suleman, M.A.4    Sapolsky, R.M.5
  • 20
    • 0034667334 scopus 로고    scopus 로고
    • The possibility of neurotoxicity in the hippocampus in major depression: A primer on neuron death
    • Sapolsky RM. The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death. Biol Psychiatr 2000; 48: 755-765.
    • (2000) Biol Psychiatr , vol.48 , pp. 755-765
    • Sapolsky, R.M.1
  • 21
    • 0035369840 scopus 로고    scopus 로고
    • Trk receptors: Mediators of neurotrophin action
    • Patapoutian A, Reichardt LF. Trk receptors: mediators of neurotrophin action. Curr Opin Neurobiol 2001; 11: 272-280.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 272-280
    • Patapoutian, A.1    Reichardt, L.F.2
  • 22
    • 0036202956 scopus 로고    scopus 로고
    • Decreased serum brain-derived neurotrophin factor levels in major depressed patients
    • Karege F, Perret G, Bondolfi G, Schwald M, Bertschy G, Aubry JM. Decreased serum brain-derived neurotrophin factor levels in major depressed patients. Psychiatr Res 2002; 109: 143-148.
    • (2002) Psychiatr Res , vol.109 , pp. 143-148
    • Karege, F.1    Perret, G.2    Bondolfi, G.3    Schwald, M.4    Bertschy, G.5    Aubry, J.M.6
  • 23
    • 0029050864 scopus 로고
    • Stress and antidepressants differentially regulate neurotrophin 3 mRNA expression in the locus coeruleus
    • Smith MA, Makino S, Altemus M, Michelson D, Hong SK, Kvetnansky R et al. Stress and antidepressants differentially regulate neurotrophin 3 mRNA expression in the locus coeruleus. Proc Natl Acad Sci USA 1995; 92: 8788-8792.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8788-8792
    • Smith, M.A.1    Makino, S.2    Altemus, M.3    Michelson, D.4    Hong, S.K.5    Kvetnansky, R.6
  • 24
    • 0029555826 scopus 로고
    • Effects of stress on neurotrophic factor expression in the rat brain
    • Smith MA, Makino S, Kvetnansky R, Post RM. Effects of stress on neurotrophic factor expression in the rat brain. Ann NY Acad Sci 1995; 771: 234-239.
    • (1995) Ann NY Acad Sci , vol.771 , pp. 234-239
    • Smith, M.A.1    Makino, S.2    Kvetnansky, R.3    Post, R.M.4
  • 25
    • 0042154427 scopus 로고    scopus 로고
    • Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects
    • Dwivedi Y, Rizavi HS, Conley RR, Roberts RC, Tamminga CA, Pandey GN. Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatr 2003; 60: 804-815.
    • (2003) Arch Gen Psychiatr , vol.60 , pp. 804-815
    • Dwivedi, Y.1    Rizavi, H.S.2    Conley, R.R.3    Roberts, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 26
    • 0037092425 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
    • Shirayama Y, Chen AC, Nakagawa S, Russell DS, Duman RS. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci 2002; 22: 3251-3261.
    • (2002) J Neurosci , vol.22 , pp. 3251-3261
    • Shirayama, Y.1    Chen, A.C.2    Nakagawa, S.3    Russell, D.S.4    Duman, R.S.5
  • 27
    • 0036460741 scopus 로고    scopus 로고
    • Selective chronic stress-induced in vivo ERK1/2 hyperphosphorylation in medial prefrontocortical dendrites: Implications for stress-related cortical pathology?
    • Trentani A, Kuipers SD, Ter Horst GJ, Den Boer JA. Selective chronic stress-induced in vivo ERK1/2 hyperphosphorylation in medial prefrontocortical dendrites: implications for stress-related cortical pathology? Eur J Neurosci 2002; 15: 1681-1691.
    • (2002) Eur J Neurosci , vol.15 , pp. 1681-1691
    • Trentani, A.1    Kuipers, S.D.2    Ter Horst, G.J.3    Den Boer, J.A.4
  • 28
    • 0043240266 scopus 로고    scopus 로고
    • The role of the extracellular signal-regulated kinase signaling pathway in mood modulation
    • Einat H, Yuan P, Gould TD, Li JL, Du JH, Zhang L et al. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. Soc Neurosci 2003; 23: 7311-7316.
    • (2003) Soc Neurosci , vol.23 , pp. 7311-7316
    • Einat, H.1    Yuan, P.2    Gould, T.D.3    Li, J.L.4    Du, J.H.5    Zhang, L.6
  • 29
    • 0035020808 scopus 로고    scopus 로고
    • Reduced activation and expression of ERK1/2 MAP kinase in the postmortem brain of depressed suicide subjects
    • Dwivedi Y, Rizavi HS, Roberts RC, Conley RC, Tamminga CA, Pandey GN. Reduced activation and expression of ERK1/2 MAP kinase in the postmortem brain of depressed suicide subjects. J Neurochem 2001; 77: 916-928.
    • (2001) J Neurochem , vol.77 , pp. 916-928
    • Dwivedi, Y.1    Rizavi, H.S.2    Roberts, R.C.3    Conley, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 30
    • 0026715160 scopus 로고
    • 95-Kilodalton B-Raf serine/threonine kinase: Identification of the protein and its major autophosphorylation site
    • Stephens RM, Sithanandam G, Copeland TD, Kaplan DR, Rapp UR, Morrison DK. 95-kilodalton B-Raf serine/threonine kinase: identification of the protein and its major autophosphorylation site. Mol Cell Biol 1992; 12: 3733-3742.
    • (1992) Mol Cell Biol , vol.12 , pp. 3733-3742
    • Stephens, R.M.1    Sithanandam, G.2    Copeland, T.D.3    Kaplan, D.R.4    Rapp, U.R.5    Morrison, D.K.6
  • 32
    • 0034997845 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
    • Pearson G, Robinson F, Gibson TB, Xu B-E, Karandikar M, Berman K et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 2001; 22: 153-183.
    • (2001) Endocr Rev , vol.22 , pp. 153-183
    • Pearson, G.1    Robinson, F.2    Gibson, T.B.3    Xu, B.-E.4    Karandikar, M.5    Berman, K.6
  • 33
    • 0025266334 scopus 로고
    • Expression of Raf family proto-oncogenes in normal mouse tissues
    • Storm SM, Cleveland JL, Rapp UR. Expression of Raf family proto-oncogenes in normal mouse tissues. Oncogene 1990; 5: 345-351.
    • (1990) Oncogene , vol.5 , pp. 345-351
    • Storm, S.M.1    Cleveland, J.L.2    Rapp, U.R.3
  • 34
    • 0030963439 scopus 로고    scopus 로고
    • cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway
    • Vossler MR, Yao H, York RD, Pan MG, Rim CS, Stork PJS. cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell 1997; 89: 73-82.
    • (1997) Cell , vol.89 , pp. 73-82
    • Vossler, M.R.1    Yao, H.2    York, R.D.3    Pan, M.G.4    Rim, C.S.5    Stork, P.J.S.6
  • 36
    • 0010166469 scopus 로고    scopus 로고
    • The activation of B-Raf and Raf-1 after electroconvulsive shock in the rat hippocampus
    • Kang UG, Jeon SH, Lee JE, Joo Y-H, Yi JS, Park J-B et al. The activation of B-Raf and Raf-1 after electroconvulsive shock in the rat hippocampus. Neuropharmacology 2000; 39: 703-706.
    • (2000) Neuropharmacology , vol.39 , pp. 703-706
    • Kang, U.G.1    Jeon, S.H.2    Lee, J.E.3    Joo, Y.-H.4    Yi, J.S.5    Park, J.-B.6
  • 37
    • 0028845078 scopus 로고
    • The relative importance of premortem acidosis and postmortem interval for human brain gene expression studies: Selective mRNA vulnerability and comparison with their encoded proteins
    • Harrison PJ, Heath PR, Eastwood SL, Burnet PW, McDonald B, Pearson RC. The relative importance of premortem acidosis and postmortem interval for human brain gene expression studies: selective mRNA vulnerability and comparison with their encoded proteins. Neurosci Lett 1995; 200: 151-154.
    • (1995) Neurosci Lett , vol.200 , pp. 151-154
    • Harrison, P.J.1    Heath, P.R.2    Eastwood, S.L.3    Burnet, P.W.4    McDonald, B.5    Pearson, R.C.6
  • 42
    • 0028809479 scopus 로고
    • The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression
    • Barnier JV, Papin C, Eychene A, Lecoq O, Calothy G. The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression. J Biol Chem 1995; 270: 23381-23389.
    • (1995) J Biol Chem , vol.270 , pp. 23381-23389
    • Barnier, J.V.1    Papin, C.2    Eychene, A.3    Lecoq, O.4    Calothy, G.5
  • 43
    • 0025604178 scopus 로고
    • Complete coding sequence of a human B-raf cDNA and detection of B-raf protein kinase with isozyme specific antibodies
    • Sithanandam G, Kolch W, Duh FM, Rapp UR. Complete coding sequence of a human B-raf cDNA and detection of B-raf protein kinase with isozyme specific antibodies. Oncogene 1990; 5: 1775-1780.
    • (1990) Oncogene , vol.5 , pp. 1775-1780
    • Sithanandam, G.1    Kolch, W.2    Duh, F.M.3    Rapp, U.R.4
  • 44
    • 0033010541 scopus 로고    scopus 로고
    • Raf-1 and B-Raf proteins have similar regional distributions but differential subcellular localization in adult rat brain
    • Morice C, Nothias F, Konig S, Vernier P, Baccarini M, Vincent JD et al. Raf-1 and B-Raf proteins have similar regional distributions but differential subcellular localization in adult rat brain. Eur J Neurosci 1999; 11: 1995-2006.
    • (1999) Eur J Neurosci , vol.11 , pp. 1995-2006
    • Morice, C.1    Nothias, F.2    Konig, S.3    Vernier, P.4    Baccarini, M.5    Vincent, J.D.6
  • 45
    • 0029006126 scopus 로고
    • Ras-GTP translocates Raf-1 to the plasma membrane where it becomes phosphorylated on tyrosine residues 340 and 341 by membrane bound tyrosine kinases
    • Marais R, Light Y, Paterson HF, Marshall CJ. Ras-GTP translocates Raf-1 to the plasma membrane where it becomes phosphorylated on tyrosine residues 340 and 341 by membrane bound tyrosine kinases. EMBO J 1995; 14: 3136-3145.
    • (1995) EMBO J , vol.14 , pp. 3136-3145
    • Marais, R.1    Light, Y.2    Paterson, H.F.3    Marshall, C.J.4
  • 46
    • 0031041171 scopus 로고    scopus 로고
    • Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic Ras and tyrosine kinases
    • Marais R, Light Y, Paterson HF, Mason CS, Marshall CJ. Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic Ras and tyrosine kinases. J Biol Chem 1997; 14: 4378-4383.
    • (1997) J Biol Chem , vol.14 , pp. 4378-4383
    • Marais, R.1    Light, Y.2    Paterson, H.F.3    Mason, C.S.4    Marshall, C.J.5
  • 48
    • 0027945787 scopus 로고
    • Partial purification of a mitogen-activated protein kinase kinase activator from bovine brain. Identification as B-Raf or a B-Raf-associated activity
    • Catling AD, Reuter CW, Cox ME, Parsons SJ, Weber MJ. Partial purification of a mitogen-activated protein kinase kinase activator from bovine brain. Identification as B-Raf or a B-Raf-associated activity. J Biol Chem 1994; 269: 30014-30021.
    • (1994) J Biol Chem , vol.269 , pp. 30014-30021
    • Catling, A.D.1    Reuter, C.W.2    Cox, M.E.3    Parsons, S.J.4    Weber, M.J.5
  • 50
    • 0032499282 scopus 로고    scopus 로고
    • Rap1 mediates sustained MAP kinase activation induced by nerve growth factor
    • York RD, Yao H, Dillon T, Ellig CL, Eckert SP, McCleskey EW et al. Rap1 mediates sustained MAP kinase activation induced by nerve growth factor. Nature 1998; 392: 622-626.
    • (1998) Nature , vol.392 , pp. 622-626
    • York, R.D.1    Yao, H.2    Dillon, T.3    Ellig, C.L.4    Eckert, S.P.5    McCleskey, E.W.6
  • 51
    • 0035947724 scopus 로고    scopus 로고
    • Differential activation of the MAPK cascade by epidermal growth factor and nerve growth factor in PC12 cells
    • Kao S, Jaiswal RK, Kolch W, Landreth GE. Differential activation of the MAPK cascade by epidermal growth factor and nerve growth factor in PC12 cells. J Biol Chem 2001; 276: 18169-18177.
    • (2001) J Biol Chem , vol.276 , pp. 18169-18177
    • Kao, S.1    Jaiswal, R.K.2    Kolch, W.3    Landreth, G.E.4
  • 52
    • 0035451062 scopus 로고    scopus 로고
    • To be or not to be: A question of B-Raf?
    • Kolch W. To be or not to be: a question of B-Raf? Trends Neurosci 2001; 24: 498-500.
    • (2001) Trends Neurosci , vol.24 , pp. 498-500
    • Kolch, W.1
  • 53
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall CJ. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 1995; 80: 179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 54
    • 0029058730 scopus 로고
    • Purification of a Ras-dependent mitogen-activated protein kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins
    • Yamamori B, Kuroda S, Shimizu K, Fukui K, Ohtsuka T, Takai Y et al. Purification of a Ras-dependent mitogen-activated protein kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins. J Biol Chem 1995; 270: 11723-11726.
    • (1995) J Biol Chem , vol.270 , pp. 11723-11726
    • Yamamori, B.1    Kuroda, S.2    Shimizu, K.3    Fukui, K.4    Ohtsuka, T.5    Takai, Y.6
  • 55
    • 0032531756 scopus 로고    scopus 로고
    • Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signaling
    • Zwartkruis FJ, Wolthuis RM, Nabben NM, Franke B, Bos JL. Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signaling. EMBO J 1998; 17: 5905-5912.
    • (1998) EMBO J , vol.17 , pp. 5905-5912
    • Zwartkruis, F.J.1    Wolthuis, R.M.2    Nabben, N.M.3    Franke, B.4    Bos, J.L.5
  • 56
    • 0033520311 scopus 로고    scopus 로고
    • Differential effects of cAMP in neurons and astrocytes. Role of B-raf
    • Dugan LL, Kim JS, Zhang Y, Bart RD, Sun Y, Holtzman DM et al. Differential effects of cAMP in neurons and astrocytes. Role of B-raf. J Biol Chem 1999; 274: 25842-25848.
    • (1999) J Biol Chem , vol.274 , pp. 25842-25848
    • Dugan, L.L.1    Kim, J.S.2    Zhang, Y.3    Bart, R.D.4    Sun, Y.5    Holtzman, D.M.6
  • 58
    • 0030048696 scopus 로고    scopus 로고
    • Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein
    • Ohtsuka T, Shimizu K, Yamamori B, Kuroda S, Takai Y. Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein. J Biol Chem 1996; 271: 1258-1261.
    • (1996) J Biol Chem , vol.271 , pp. 1258-1261
    • Ohtsuka, T.1    Shimizu, K.2    Yamamori, B.3    Kuroda, S.4    Takai, Y.5
  • 59
    • 0029919472 scopus 로고    scopus 로고
    • Post-transcriptional modifications of H-Ras is required for activation of, but not for association with B-Raf
    • Okada T, Masuda T, Shinkai M, Kariya K, Kataoka T. Post-transcriptional modifications of H-Ras is required for activation of, but not for association with B-Raf. J Biol Chem 1996; 271: 4671-4678.
    • (1996) J Biol Chem , vol.271 , pp. 4671-4678
    • Okada, T.1    Masuda, T.2    Shinkai, M.3    Kariya, K.4    Kataoka, T.5
  • 62
    • 0034644733 scopus 로고    scopus 로고
    • Cell type-specific regulation of B-Raf kinase by cAMP and 14-3-3 proteins
    • Qiu W, Zhuang S, von Lintig FC, Boss GR, Pilz RB. Cell type-specific regulation of B-Raf kinase by cAMP and 14-3-3 proteins. J Biol Chem 2000; 275: 31921-31929.
    • (2000) J Biol Chem , vol.275 , pp. 31921-31929
    • Qiu, W.1    Zhuang, S.2    Von Lintig, F.C.3    Boss, G.R.4    Pilz, R.B.5
  • 63
    • 0034682836 scopus 로고    scopus 로고
    • 2-adrenergic receptor activates extracellular regulated kinases (ERKs) via the small G protein Rap1 and the serine/threonine kinase B-Raf
    • 2-adrenergic receptor activates extracellular regulated kinases (ERKs) via the small G protein Rap1 and the serine/threonine kinase B-Raf. J Biol Chem 2002; 275: 25342-25350.
    • (2002) J Biol Chem , vol.275 , pp. 25342-25350
    • Schmitt, J.M.1    Stork, P.J.S.2
  • 64
    • 0035853827 scopus 로고    scopus 로고
    • cAMP-dependent protein kinase induces cAMP-response element-binding protein phosphorylation via an intracellular calcium release/ERK-dependent pathway in striatal neurons
    • Zanassi P, Paolillo M, Feliciello A, Avvedimento EV, Galloand V, Schinelli S. cAMP-dependent protein kinase induces cAMP-response element-binding protein phosphorylation via an intracellular calcium release/ERK-dependent pathway in striatal neurons. J Biol Chem 2001; 276: 11487-11495.
    • (2001) J Biol Chem , vol.276 , pp. 11487-11495
    • Zanassi, P.1    Paolillo, M.2    Feliciello, A.3    Avvedimento, E.V.4    Galloand, V.5    Schinelli, S.6
  • 65
    • 9144253896 scopus 로고    scopus 로고
    • Protein kinase A in postmortem brain of depressed suicide victims: Altered expression of specific regulatory and catalytic subunits
    • Dwivedi Y, Rizavi HS, Shukla PK, Lyons J, Faludi G, Palkovits M et al. Protein kinase A in postmortem brain of depressed suicide victims: altered expression of specific regulatory and catalytic subunits. Biol Psychiatr 2004; 55: 234-243.
    • (2004) Biol Psychiatr , vol.55 , pp. 234-243
    • Dwivedi, Y.1    Rizavi, H.S.2    Shukla, P.K.3    Lyons, J.4    Faludi, G.5    Palkovits, M.6
  • 68
    • 0029810672 scopus 로고    scopus 로고
    • cAMP-dependent protein kinase activity in major depression
    • Shelton RC, Mainer DH, Sulser F. cAMP-dependent protein kinase activity in major depression. Am J Psychiatr 1996; 153: 1037-1042.
    • (1996) Am J Psychiatr , vol.153 , pp. 1037-1042
    • Shelton, R.C.1    Mainer, D.H.2    Sulser, F.3
  • 70
    • 0001817672 scopus 로고    scopus 로고
    • Neuroimaging studies of mood disorders
    • Charney DS, Nestler EJ, Bunney BS (eds.), New York: Oxford UP
    • Drevets WC, Gadde KM, Krishman KR. Neuroimaging studies of mood disorders. In: Charney DS, Nestler EJ, Bunney BS (eds.), Neurobiology of Mental Illness. New York: Oxford UP, 1999, pp. 394-418.
    • (1999) Neurobiology of Mental Illness , pp. 394-418
    • Drevets, W.C.1    Gadde, K.M.2    Krishman, K.R.3
  • 73
    • 0032527572 scopus 로고    scopus 로고
    • A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives
    • Benes FM, Kwok EW, Vincent SL, Todtankopf MS. A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives. Biol Psychiatr 1998; 15: 88-97.
    • (1998) Biol Psychiatr , vol.15 , pp. 88-97
    • Benes, F.M.1    Kwok, E.W.2    Vincent, S.L.3    Todtankopf, M.S.4
  • 74
    • 0035336748 scopus 로고    scopus 로고
    • Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder
    • Rajkowska G, Halaris A, Selemon LD. Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder. Biol Psychiatr 2001; 49: 741-752.
    • (2001) Biol Psychiatr , vol.49 , pp. 741-752
    • Rajkowska, G.1    Halaris, A.2    Selemon, L.D.3
  • 75
    • 0036178441 scopus 로고    scopus 로고
    • Molecular psychology: Roles for the ERK MAP kinase cascade in memory
    • Adams JP, Sweatt JD. Molecular psychology: roles for the ERK MAP kinase cascade in memory. Annu Rev Pharmacol Toxicol 2002; 42: 135-163.
    • (2002) Annu Rev Pharmacol Toxicol , vol.42 , pp. 135-163
    • Adams, J.P.1    Sweatt, J.D.2
  • 76
    • 0142090726 scopus 로고    scopus 로고
    • Impairments of ERK signal transduction in the brain in a rat model of depression induced by neonatal exposure of clomipramine
    • Feng P, Guan Z, Yang X, Fang J. Impairments of ERK signal transduction in the brain in a rat model of depression induced by neonatal exposure of clomipramine. Brain Res 2003; 991: 195-205.
    • (2003) Brain Res , vol.991 , pp. 195-205
    • Feng, P.1    Guan, Z.2    Yang, X.3    Fang, J.4
  • 77
    • 23444435759 scopus 로고    scopus 로고
    • MAP kinase activation by fluoxetine and its relation to gene expression in cultured rat astrocytes
    • Mercier G, Lennon AM, Renouf B, Dessouroux A, Ramauge M, Courtin F et al. MAP kinase activation by fluoxetine and its relation to gene expression in cultured rat astrocytes. J Mol Neurosci 2004; 24: 207-216.
    • (2004) J Mol Neurosci , vol.24 , pp. 207-216
    • Mercier, G.1    Lennon, A.M.2    Renouf, B.3    Dessouroux, A.4    Ramauge, M.5    Courtin, F.6
  • 78
    • 0035146138 scopus 로고    scopus 로고
    • Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons
    • Wiese S, Pei G, Karch C, Troppmair J, Holtmann B, Rapp UR et al. Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons. Nat Neurosci 2001; 4: 137-142.
    • (2001) Nat Neurosci , vol.4 , pp. 137-142
    • Wiese, S.1    Pei, G.2    Karch, C.3    Troppmair, J.4    Holtmann, B.5    Rapp, U.R.6
  • 80
    • 17744384002 scopus 로고    scopus 로고
    • Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene
    • Mikula M, Schreiber M, Husak Z, Kucerova L, Ruth J, Wieser R et al. Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene. EMBO J 2001; 8: 1952-1962.
    • (2001) EMBO J , vol.8 , pp. 1952-1962
    • Mikula, M.1    Schreiber, M.2    Husak, Z.3    Kucerova, L.4    Ruth, J.5    Wieser, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.