The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 35, Issue 7, 2011, Pages 1774-1779

  Jernigan, Courtney S ^a   Goswami, Dharmendra B ^a   Austin, Mark C ^a   Iyo, Abiye H ^a   Chandran, Agata ^a   Stockmeier, Craig A ^a,b   Karolewicz, Beata ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Major depressive disorder; Postmortem; Prefrontal cortex; Translation initiation pathway

Indexed keywords

INITIATION FACTOR 4B; INITIATION FACTOR 4E; MAMMALIAN TARGET OF RAPAMYCIN; METABOTROPIC RECEPTOR 5; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; POSTSYNAPTIC DENSITY PROTEIN 95; S6 KINASE; SERINE;

ADULT; AGED; ARTICLE; BRAIN CORTEX; CADAVER; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MAJOR DEPRESSION; MALE; PATHOGENESIS; POSTSYNAPTIC POTENTIAL; PREFRONTAL CORTEX; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSLATION INITIATION; TRANSLATION REGULATION; WESTERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; AUTOPSY; DEPRESSIVE DISORDER, MAJOR; EUKARYOTIC INITIATION FACTORS; FAMILY; FEMALE; HUMANS; MALE; MIDDLE AGED; PREFRONTAL CORTEX; RIBOSOMAL PROTEIN S6 KINASES; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 79961129428     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2011.05.010     Document Type: Article

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