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Volumn 28, Issue 5, 2009, Pages 525-542

Epa but not dha appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: Evidence from a meta-analysis of randomized controlled trials

Author keywords

[No Author keywords available]

Indexed keywords

DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID;

EID: 77954947300     PISSN: 07315724     EISSN: 15411087     Source Type: Journal    
DOI: 10.1080/07315724.2009.10719785     Document Type: Article
Times cited : (293)

References (97)
  • 4
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • Mathers CD, Loncar D: Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 3:442, 2006.
    • (2006) Plos Med , vol.3 , pp. 442
    • Mathers, C.D.1    Loncar, D.2
  • 5
    • 0024542891 scopus 로고
    • Increasing rates of depression
    • Klerman GL, Weissman MM: Increasing rates of depression. JAMA 261:2229-2235, 1989.
    • (1989) JAMA , vol.261 , pp. 2229-2235
    • Klerman, G.L.1    Weissman, M.M.2
  • 6
    • 48249126487 scopus 로고    scopus 로고
    • Widening of socioeconomic inequalities in u.S. Death rates, 1993-2001
    • Jemal A, Ward E, Anderson RN, Murray T, Thun MJ: Widening of socioeconomic inequalities in U.S. death rates, 1993-2001. PLoS One 3: 2181, 2008.
    • (2008) Plos One , vol.3 , pp. 2181
    • Jemal, A.1    Ward, E.2    Erson, R.N.3    Murray, T.4    Thun, M.J.5
  • 7
    • 38749147289 scopus 로고    scopus 로고
    • Coronary heart disease trends in england and wales from 1984 to 2004: Concealed levelling of mortality rates among young adults
    • O'Flaherty M, Ford E, Allender S, Scarborough P, Capewell S: Coronary heart disease trends in England and Wales from 1984 to 2004: concealed levelling of mortality rates among young adults. Heart 94:178-181, 2008.
    • (2008) Heart , vol.94 , pp. 178-181
    • O'Flaherty, M.1    Ford, E.2    Allender, S.3    Scarborough, P.4    Capewell, S.5
  • 8
    • 38849095188 scopus 로고    scopus 로고
    • Cardiovascular disease and depression: The pufa connection
    • Puri BK: Cardiovascular disease and depression: the PUFA connection. Int J Clin Pract 62:355-357, 2008.
    • (2008) Int J Clin Pract , vol.62 , pp. 355-357
    • Puri, B.K.1
  • 9
    • 30544445602 scopus 로고    scopus 로고
    • Cytokines sing the blues: Inflammation and the pathogenesis of depression
    • Raison CL, Capuron L, Miller AH: Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunol 27:24-31, 2006.
    • (2006) Trends Immunol , vol.27 , pp. 24-31
    • Raison, C.L.1    Capuron, L.2    Miller, A.H.3
  • 10
    • 33845291521 scopus 로고    scopus 로고
    • Cytokine-effects on glucocorticoid receptor function: Relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression
    • Pace TW, Hu F, Miller AH: Cytokine-effects on glucocorticoid receptor function: relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression. Brain Behav Immun 21:9-19, 2007.
    • (2007) Brain Behav Immun , vol.21 , pp. 9-19
    • Pace, T.W.1    Hu, F.2    Miller, A.H.3
  • 11
    • 33746830525 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases
    • Calder PC: n-3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am J Clin Nutr 83:1505S-1519S, 2006.
    • (2006) Am J Clin Nutr , vol.83 , pp. 1505S-1519S
    • Calder, P.C.1
  • 15
    • 0032542958 scopus 로고    scopus 로고
    • Fish consumption and major depression
    • Hibbeln JR: Fish consumption and major depression. Lancet 351:1213, 1998.
    • (1998) Lancet , vol.351 , pp. 1213
    • Hibbeln, J.R.1
  • 16
    • 0036018481 scopus 로고    scopus 로고
    • Seafood consumption, the dha content of mothers' milk and prevalence rates of postpartum depression: A crossnational, ecological analysis
    • Hibbeln JR: Seafood consumption, the DHA content of mothers' milk and prevalence rates of postpartum depression: a crossnational, ecological analysis. J Affect Disord 69:15-29, 2002.
    • (2002) J Affect Disord , vol.69 , pp. 15-29
    • Hibbeln, J.R.1
  • 17
    • 0037668364 scopus 로고    scopus 로고
    • Cross-national comparisons of seafood consumption and rates of bipolar disorders
    • Noaghiul S, Hibbeln JR: Cross-national comparisons of seafood consumption and rates of bipolar disorders. Am J Psychiatry 160:2222-2227, 2003.
    • (2003) Am J Psychiatry , vol.160 , pp. 2222-2227
    • Noaghiul, S.1    Hibbeln, J.R.2
  • 18
    • 0036276031 scopus 로고    scopus 로고
    • Fish consumption and self-reported physical and mental health status
    • Silvers KM, Scott KM: Fish consumption and self-reported physical and mental health status. Public Health Nutr 5:427-431, 2002.
    • (2002) Public Health Nutr , vol.5 , pp. 427-431
    • Silvers, K.M.1    Scott, K.M.2
  • 21
    • 0001467343 scopus 로고    scopus 로고
    • Arachidonic acid to eicosapentaenoic acid ratio in blood correlates positively with clinical symptoms of depression
    • Adams PB, Lawson S, Sanigorski A, Sinclair AJ: Arachidonic acid to eicosapentaenoic acid ratio in blood correlates positively with clinical symptoms of depression. Lipids 31 Suppl:S157-S161, 1996.
    • (1996) Lipids 31 Suppl , pp. S157-S161
    • Adams, P.B.1    Lawson, S.2    Sanigorski, A.3    Sinclair, A.J.4
  • 22
    • 34447108057 scopus 로고    scopus 로고
    • Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers
    • Conklin SM, Harris JI, Manuck SB, Yao JK, Hibbeln JR, Muldoon MF: Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers. Psychiatry Res 152:1-10, 2007.
    • (2007) Psychiatry Res , vol.152 , pp. 1-10
    • Conklin, S.M.1    Harris, J.I.2    Manuck, S.B.3    Yao, J.K.4    Hibbeln, J.R.5    Muldoon, M.F.6
  • 23
    • 0031781242 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acid levels in the diet and in red blood cell membranes of depressed patients
    • Edwards R, Peet M, Shay J, Horrobin D: Omega-3 polyunsaturated fatty acid levels in the diet and in red blood cell membranes of depressed patients. J Affect Disord 48:149-155, 1998.
    • (1998) J Affect Disord , vol.48 , pp. 149-155
    • Edwards, R.1    Peet, M.2    Shay, J.3    Horrobin, D.4
  • 24
    • 43549095504 scopus 로고    scopus 로고
    • Plasma eicosapentaenoic acid is inversely associated with severity of depressive symptomatology in the elderly: Data from the bordeaux sample of the three-city study
    • Féart C, Peuchant E, Letenneur L, Samieri C, Montagnier D, Fourrier-Reglat A, Barberger-Gateau P: Plasma eicosapentaenoic acid is inversely associated with severity of depressive symptomatology in the elderly: data from the Bordeaux sample of the Three-City Study. Am J Clin Nutr 87:1156-1162, 2008.
    • (2008) Am J Clin Nutr , vol.87 , pp. 1156-1162
    • Féart, C.1    Peuchant, E.2    Letenneur, L.3    Samieri, C.4    Montagnier, D.5    Fourrier-Reglat, A.6    Barberger-Gateau, P.7
  • 25
    • 0033593975 scopus 로고    scopus 로고
    • Lowered omega3 polyunsaturated fatty acids in serum phospholipids and cholesteryl esters of depressed patients
    • Maes M, Christophe A, Delanghe J, Altamura C, Neels H, Meltzer HY: Lowered omega3 polyunsaturated fatty acids in serum phospholipids and cholesteryl esters of depressed patients. Psychiatry Res 85:275-291, 1999.
    • (1999) Psychiatry Res , vol.85 , pp. 275-291
    • Maes, M.1    Christophe, A.2    Delanghe, J.3    Altamura, C.4    Neels, H.5    Meltzer, H.Y.6
  • 26
    • 0029973068 scopus 로고    scopus 로고
    • Fatty acid composition in major depression: Decreased omega 3 fractions in cholesteryl esters and increased c20: 4 omega 6/c20:5 omega 3 ratio in cholesteryl esters and phospholipids
    • Maes M, Smith R, Christophe A, Cosyns P, Desnyder R, Meltzer H: Fatty acid composition in major depression: decreased omega 3 fractions in cholesteryl esters and increased C20: 4 omega 6/C20:5 omega 3 ratio in cholesteryl esters and phospholipids. J Affect Disord 38:35-46, 1996.
    • (1996) J Affect Disord , vol.38 , pp. 35-46
    • Maes, M.1    Smith, R.2    Christophe, A.3    Cosyns, P.4    Desnyder, R.5    Meltzer, H.6
  • 27
    • 0032031290 scopus 로고    scopus 로고
    • Depletion of omega-3 fatty acid levels in red blood cell membranes of depressive patients
    • Peet M, Murphy B, Shay J, Horrobin D: Depletion of omega-3 fatty acid levels in red blood cell membranes of depressive patients. Biol Psychiatry 43:315-319, 1998.
    • (1998) Biol Psychiatry , vol.43 , pp. 315-319
    • Peet, M.1    Murphy, B.2    Shay, J.3    Horrobin, D.4
  • 28
    • 3042770776 scopus 로고    scopus 로고
    • In humans, the seasonal variation in poly-unsaturated fatty acids is related to the seasonal variation in violent suicide and serotonergic markers of violent suicide
    • De Vriese SR, Christophe AB, Maes M: In humans, the seasonal variation in poly-unsaturated fatty acids is related to the seasonal variation in violent suicide and serotonergic markers of violent suicide. Prostaglandins Leukot Essent Fatty Acids 71:13-18, 2004.
    • (2004) Prostaglandins Leukot Essent Fatty Acids , vol.71 , pp. 13-18
    • De Vriese, S.R.1    Christophe, A.B.2    Maes, M.3
  • 30
    • 84911462917 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated essential fatty acid status as a predictor of future suicide risk
    • Sublette ME, Hibbeln JR, Galfalvy H, Oquendo MA, Mann JJ: Omega-3 polyunsaturated essential fatty acid status as a predictor of future suicide risk. Am J Psychiatry 163:1100-1102, 2006.
    • (2006) Am J Psychiatry , vol.163 , pp. 1100-1102
    • Sublette, M.E.1    Hibbeln, J.R.2    Galfalvy, H.3    Oquendo, M.A.4    Mann, J.J.5
  • 31
    • 0021983786 scopus 로고
    • Sick individuals and sick populations
    • Rose G: Sick individuals and sick populations. Int J Epidemiol 14:32-38, 1985.
    • (1985) Int J Epidemiol , vol.14 , pp. 32-38
    • Rose, G.1
  • 32
    • 31444441701 scopus 로고    scopus 로고
    • New approaches to antidepressant drug discovery: Beyond monoamines
    • Berton O, Nestler EJ: New approaches to antidepressant drug discovery: beyond monoamines. Nat Rev Neurosci 7:137-151, 2006.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 137-151
    • Berton, O.1    Nestler, E.J.2
  • 33
    • 0034760815 scopus 로고    scopus 로고
    • Eicosapentaenoic acid in treatment-resistant depression associated with symptom remission, structural brain changes and reduced neuronal phospholipid turnover
    • Puri BK, Counsell SJ, Hamilton G, Richardson AJ, Horrobin DF: Eicosapentaenoic acid in treatment-resistant depression associated with symptom remission, structural brain changes and reduced neuronal phospholipid turnover. Int J Clin Pract 55:560-563, 2001.
    • (2001) Int J Clin Pract , vol.55 , pp. 560-563
    • Puri, B.K.1    Counsell, S.J.2    Hamilton, G.3    Richardson, A.J.4    Horrobin, D.F.5
  • 34
    • 29644443167 scopus 로고    scopus 로고
    • Efficacy of ethyl-eicosapentaenoic acid in bipolar depression: Randomised double-blind placebocontrolled study
    • Frangou S, Lewis M, McCrone P: Efficacy of ethyl-eicosapentaenoic acid in bipolar depression: randomised double-blind placebocontrolled study. Br J Psychiatry 188:46-50, 2006.
    • (2006) Br J Psychiatry , vol.188 , pp. 46-50
    • Frangou, S.1    Lewis, M.2    McCrone, P.3
  • 35
    • 39049148835 scopus 로고    scopus 로고
    • Comparison of therapeutic effects of omega-3 fatty acid eicosapentaenoic acid and fluoxetine, separately and in combination, in major depressive disorder
    • Jazayeri S, Tehrani-Doost M, Keshavarz SA, Hosseini M, Djazayery A, Amini H, Jalali M, Peet M: Comparison of therapeutic effects of omega-3 fatty acid eicosapentaenoic acid and fluoxetine, separately and in combination, in major depressive disorder. Aust N Z J Psychiatry 42:192-198, 2008.
    • (2008) Aust N Z J Psychiatry , vol.42 , pp. 192-198
    • Jazayeri, S.1    Tehrani-Doost, M.2    Keshavarz, S.A.3    Hosseini, M.4    Djazayery, A.5    Amini, H.6    Jalali, M.7    Peet, M.8
  • 36
    • 0036190807 scopus 로고    scopus 로고
    • Addition of omega-3 fatty acid to maintenance medication treatment for recurrent unipolar depressive disorder
    • Nemets B, Stahl Z, Belmaker RH: Addition of omega-3 fatty acid to maintenance medication treatment for recurrent unipolar depressive disorder. Am J Psychiatry 159:477-479, 2002.
    • (2002) Am J Psychiatry , vol.159 , pp. 477-479
    • Nemets, B.1    Stahl, Z.2    Belmaker, R.H.3
  • 37
    • 0036790628 scopus 로고    scopus 로고
    • A dose-ranging study of the effects of ethyleicosapentaenoate in patients with ongoing depression despite apparently adequate treatment with standard drugs
    • Peet M, Horrobin DF: A dose-ranging study of the effects of ethyleicosapentaenoate in patients with ongoing depression despite apparently adequate treatment with standard drugs. Arch Gen Psychiatry 59:913-919, 2002.
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 913-919
    • Peet, M.1    Horrobin, D.F.2
  • 39
    • 0042850504 scopus 로고    scopus 로고
    • Omega-3 fatty acids in major depressive disorder. A preliminary double-blind, placebocontrolled trial
    • Su KP, Huang SY, Chiu CC, Shen WW: Omega-3 fatty acids in major depressive disorder. A preliminary double-blind, placebocontrolled trial. Eur Neuropsychopharmacol 13:267-271, 2003.
    • (2003) Eur Neuropsychopharmacol , vol.13 , pp. 267-271
    • Su, K.P.1    Huang, S.Y.2    Chiu, C.C.3    Shen, W.W.4
  • 40
    • 44849092681 scopus 로고    scopus 로고
    • Omega-3 fatty acids for major depressive disorder during pregnancy: Results from a randomized, double-blind, placebo-controlled trial
    • Su KP, Huang SY, Chiu TH, Huang KC, Huang CL, Chang HC, Pariante CM: Omega-3 fatty acids for major depressive disorder during pregnancy: results from a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry 69:644-651, 2008.
    • (2008) J Clin Psychiatry , vol.69 , pp. 644-651
    • Su, K.P.1    Huang, S.Y.2    Chiu, T.H.3    Huang, K.C.4    Huang, C.L.5    Chang, H.C.6    Pariante, C.M.7
  • 41
    • 33846993443 scopus 로고    scopus 로고
    • Omega-3 fatty acid supplementation in patients with recurrent self-harm. Singlecentre double-blind randomised controlled trial
    • Hallahan B, Hibbeln JR, Davis JM, Garland MR: Omega-3 fatty acid supplementation in patients with recurrent self-harm. Singlecentre double-blind randomised controlled trial. Br J Psychiatry 190:118-122, 2007.
    • (2007) Br J Psychiatry , vol.190 , pp. 118-122
    • Hallahan, B.1    Hibbeln, J.R.2    Davis, J.M.3    Garland, M.R.4
  • 42
    • 54049153609 scopus 로고    scopus 로고
    • Depression in parkinson's disease: A double-blind, randomized, placebo-controlled pilot study of omega-3 fatty-acid supplementation
    • da Silva TM, Munhoz RP, Alvarez C, Naliwaiko K, Kiss A, Andreatini R, Ferraz AC: Depression in Parkinson's disease: a double-blind, randomized, placebo-controlled pilot study of omega-3 fatty-acid supplementation. J Affect Disord 111:351-359, 2008.
    • (2008) J Affect Disord , vol.111 , pp. 351-359
    • Da Silva, T.M.1    Munhoz, R.P.2    Alvarez, C.3    Naliwaiko, K.4    Kiss, A.5    Reatini, R.6    Ferraz, A.C.7
  • 43
    • 85047698720 scopus 로고    scopus 로고
    • Omega-3 treatment of childhood depression: A controlled, double-blind pilot study
    • Nemets H, Nemets B, Apter A, Bracha Z, Belmaker RH: Omega-3 treatment of childhood depression: a controlled, double-blind pilot study. Am J Psychiatry 163:1098-1100, 2006.
    • (2006) Am J Psychiatry , vol.163 , pp. 1098-1100
    • Nemets, H.1    Nemets, B.2    Apter, A.3    Bracha, Z.4    Belmaker, R.H.5
  • 44
    • 0025134274 scopus 로고
    • Effect of high doses of essential fatty acids on the postviral fatigue syndrome
    • Behan PO, Behan WM, Horrobin D: Effect of high doses of essential fatty acids on the postviral fatigue syndrome. Acta Neurol Scand 82:209-216, 1990.
    • (1990) Acta Neurol Scand , vol.82 , pp. 209-216
    • Behan, P.O.1    Behan, W.M.2    Horrobin, D.3
  • 45
    • 0035190361 scopus 로고    scopus 로고
    • A placebo-controlled trial of omega-3 fatty acid (Ethyl eicosapentaenoic acid) supplementation for residual symptoms and cognitive impairment in schizophrenia
    • Fenton WS, Dickerson F, Boronow J, Hibbeln JR, Knable M: A placebo-controlled trial of omega-3 fatty acid (ethyl eicosapentaenoic acid) supplementation for residual symptoms and cognitive impairment in schizophrenia. Am J Psychiatry 158:2071-2074, 2001.
    • (2001) Am J Psychiatry , vol.158 , pp. 2071-2074
    • Fenton, W.S.1    Dickerson, F.2    Boronow, J.3    Hibbeln, J.R.4    Knable, M.5
  • 46
    • 34447564983 scopus 로고    scopus 로고
    • Preliminary in vivo evidence of increased n-acetyl-aspartate following eicosapentanoic acid treatment in patients with bipolar disorder
    • Frangou S, Lewis M, Wollard J, Simmons A: Preliminary in vivo evidence of increased N-acetyl-aspartate following eicosapentanoic acid treatment in patients with bipolar disorder. J Psychopharmacol 21:435-439, 2007.
    • (2007) J Psychopharmacol , vol.21 , pp. 435-439
    • Frangou, S.1    Lewis, M.2    Wollard, J.3    Simmons, A.4
  • 49
    • 0038733905 scopus 로고    scopus 로고
    • Effect of maternal docosahexaenoic acid supplementation on postpartum depression and information processing
    • Llorente AM, Jensen CL, Voigt RG, Fraley JK, Berretta MC, Heird WC: Effect of maternal docosahexaenoic acid supplementation on postpartum depression and information processing. Am J Obstet Gynecol 188:1348-1353, 2003.
    • (2003) Am J Obstet Gynecol , vol.188 , pp. 1348-1353
    • Llorente, A.M.1    Jensen, C.L.2    Voigt, R.G.3    Fraley, J.K.4    Berretta, M.C.5    Heird, W.C.6
  • 50
    • 0037844785 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression
    • Marangell LB, Martinez JM, Zboyan HA, Kertz B, Kim HF, Puryear LJ: A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am J Psychiatry 160:996-998, 2003.
    • (2003) Am J Psychiatry , vol.160 , pp. 996-998
    • Marangell, L.B.1    Martinez, J.M.2    Zboyan, H.A.3    Kertz, B.4    Kim, H.F.5    Puryear, L.J.6
  • 51
    • 39049120230 scopus 로고    scopus 로고
    • Omega-3 fatty acids as a treatment for perinatal depression: Randomized double-blind placebo-controlled trial
    • Rees AM, Austin MP, Parker GB: Omega-3 fatty acids as a treatment for perinatal depression: randomized double-blind placebo-controlled trial. Aust N Z J Psychiatry 42:199-205, 2008.
    • (2008) Aust N Z J Psychiatry , vol.42 , pp. 199-205
    • Rees, A.M.1    Austin, M.P.2    Parker, G.B.3
  • 54
    • 0037225853 scopus 로고    scopus 로고
    • Omega-3 fatty acid treatment of women with borderline personality disorder: A double-blind, placebo-controlled pilot study
    • Zanarini MC, Frankenburg FR: omega-3 Fatty acid treatment of women with borderline personality disorder: a double-blind, placebo-controlled pilot study. AmJ Psychiatry 160:167-169, 2003.
    • (2003) Amj Psychiatry , vol.160 , pp. 167-169
    • Zanarini, M.C.1    Frankenburg, F.R.2
  • 55
    • 0032897006 scopus 로고    scopus 로고
    • The role of essential fatty acids in chronic fatigue syndrome. A case-controlled study of redcell membrane essential fatty acids (efa) and a placebocontrolled treatment study with high dose of efa
    • Warren G, McKendrick M, Peet M: The role of essential fatty acids in chronic fatigue syndrome. A case-controlled study of redcell membrane essential fatty acids (EFA) and a placebocontrolled treatment study with high dose of EFA. Acta Neurol Scand 99:112-116, 1999.
    • (1999) Acta Neurol Scand , vol.99 , pp. 112-116
    • Warren, G.1    McKendrick, M.2    Peet, M.3
  • 57
    • 44849122926 scopus 로고    scopus 로고
    • Omega-3 fatty acids and supportive psychotherapy for perinatal depression: A randomized placebo-controlled study
    • Freeman MP, Davis M, Sinha P, Wisner KL, Hibbeln JR, Gelenberg AJ: Omega-3 fatty acids and supportive psychotherapy for perinatal depression: a randomized placebo-controlled study. J Affect Disord 110:142-148, 2008.
    • (2008) J Affect Disord , vol.110 , pp. 142-148
    • Freeman, M.P.1    Davis, M.2    Sinha, P.3    Wisner, K.L.4    Hibbeln, J.R.5    Gelenberg, A.J.6
  • 58
    • 59749092927 scopus 로고    scopus 로고
    • Ethyleicosapentaenoic acid for the treatment of psychological distress and depressive symptoms in middle-aged women: A double-blind, placebo-controlled, randomized clinical trial
    • Lucas M, Asselin G, Merette C, Poulin MJ, Dodin S: Ethyleicosapentaenoic acid for the treatment of psychological distress and depressive symptoms in middle-aged women: a double-blind, placebo-controlled, randomized clinical trial. Am J Clin Nutr 89:641-651, 2009.
    • (2009) Am J Clin Nutr , vol.89 , pp. 641-651
    • Lucas, M.1    Asselin, G.2    Merette, C.3    Poulin, M.J.4    Dodin, S.5
  • 61
    • 34548315737 scopus 로고    scopus 로고
    • A meta-analytic review of double-blind, placebocontrolled trials of antidepressant efficacy of omega-3 fatty acids
    • Lin PY, Su KP: A meta-analytic review of double-blind, placebocontrolled trials of antidepressant efficacy of omega-3 fatty acids. J Clin Psychiatry 68:1056-1061, 2007.
    • (2007) J Clin Psychiatry , vol.68 , pp. 1056-1061
    • Lin, P.Y.1    Su, K.P.2
  • 62
  • 63
    • 36048989288 scopus 로고    scopus 로고
    • Omega-3 fatty acids as treatments for mental illness: Which disorder and which fatty acid?
    • Ross BM, Seguin J, Sieswerda LE: Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid? Lipids Health Dis 6:21, 2007.
    • (2007) Lipids Health Dis , vol.6 , pp. 21
    • Ross, B.M.1    Seguin, J.2    Sieswerda, L.E.3
  • 64
    • 1542285471 scopus 로고    scopus 로고
    • A placebo-controlled cross-over trial of adjunctive epa in ocd
    • Fux M, Benjamin J, Nemets B: A placebo-controlled cross-over trial of adjunctive EPA in OCD. J Psychiatr Res 38:323-325, 2004.
    • (2004) J Psychiatr Res , vol.38 , pp. 323-325
    • Fux, M.1    Benjamin, J.2    Nemets, B.3
  • 67
    • 35748956807 scopus 로고    scopus 로고
    • A systematic comparison of software dedicated to meta-analysis of causal studies
    • Bax L, Yu LM, Ikeda N, Moons KG: A systematic comparison of software dedicated to meta-analysis of causal studies. BMC Med Res Methodol 7:40, 2007.
    • (2007) BMC Med Res Methodol , vol.7 , pp. 40
    • Bax, L.1    Yu, L.M.2    Ikeda, N.3    Moons, K.G.4
  • 72
    • 16544366703 scopus 로고    scopus 로고
    • Docosahexaenoic acid concentrations are higher in women than in men because of estrogenic effects
    • Giltay EJ, Gooren LJ, Toorians AW, Katan MB, Zock PL: Docosahexaenoic acid concentrations are higher in women than in men because of estrogenic effects. Am J Clin Nutr 80:1167-1174, 2004.
    • (2004) Am J Clin Nutr , vol.80 , pp. 1167-1174
    • Giltay, E.J.1    Gooren, L.J.2    Toorians, A.W.3    Katan, M.B.4    Zock, P.L.5
  • 73
    • 0036774671 scopus 로고    scopus 로고
    • Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women
    • Burdge GC, Wootton SA: Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. Br J Nutr 88:411-420, 2002.
    • (2002) Br J Nutr , vol.88 , pp. 411-420
    • Burdge, G.C.1    Wootton, S.A.2
  • 74
    • 0028308789 scopus 로고
    • The prevalence and distribution of major depression in a national community sample: The national comorbidity survey
    • Blazer DG, Kessler RC, McGonagle KA, Swartz MS: The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey. Am J Psychiatry 151:979-986, 1994.
    • (1994) Am J Psychiatry , vol.151 , pp. 979-986
    • Blazer, D.G.1    Kessler, R.C.2    McGonagle, K.A.3    Swartz, M.S.4
  • 75
    • 68549113124 scopus 로고    scopus 로고
    • Reduced mania and depression in juvenile bipolar disorder associated with long-chain omega-3 polyunsaturated fatty acid supplementation
    • Clayton EH, Hanstock TL, Hirneth SJ, Kable CJ, Garg ML, Hazell PL: Reduced mania and depression in juvenile bipolar disorder associated with long-chain omega-3 polyunsaturated fatty acid supplementation. Eur J Clin Nutr 63:1037-1040, 2009.
    • (2009) Eur J Clin Nutr , vol.63 , pp. 1037-1040
    • Clayton, E.H.1    Hanstock, T.L.2    Hirneth, S.J.3    Kable, C.J.4    Garg, M.L.5    Hazell, P.L.6
  • 76
    • 33749482481 scopus 로고    scopus 로고
    • The effects of eicosapentaenoic acid-fortified food on inflammatory markers in healthy subjects-a randomized, placebo-controlled, double-blind study
    • Fujioka S, Hamazaki K, Itomura M, Huan M, Nishizawa H, Sawazaki S, Kitajima I, Hamazaki T: The effects of eicosapentaenoic acid-fortified food on inflammatory markers in healthy subjects-a randomized, placebo-controlled, double-blind study. J Nutr Sci Vitaminol (Tokyo) 52:261-265, 2006.
    • (2006) J Nutr Sci Vitaminol (Tokyo) , vol.52 , pp. 261-265
    • Fujioka, S.1    Hamazaki, K.2    Itomura, M.3    Huan, M.4    Nishizawa, H.5    Sawazaki, S.6    Kitajima, I.7    Hamazaki, T.8
  • 77
    • 14644401709 scopus 로고    scopus 로고
    • The effect of fish oil on physical aggression in schoolchildren-a randomized, double-blind, placebo-controlled trial
    • Itomura M, Hamazaki K, Sawazaki S, Kobayashi M, Terasawa K, Watanabe S, Hamazaki T: The effect of fish oil on physical aggression in schoolchildren-a randomized, double-blind, placebo-controlled trial. J Nutr Biochem 16:163-171, 2005.
    • (2005) J Nutr Biochem , vol.16 , pp. 163-171
    • Itomura, M.1    Hamazaki, K.2    Sawazaki, S.3    Kobayashi, M.4    Terasawa, K.5    Watanabe, S.6    Hamazaki, T.7
  • 79
    • 0036163839 scopus 로고    scopus 로고
    • A reevaluation of the exclusion criteria used in antidepressant efficacy trials
    • Posternak MA, Zimmerman M, Keitner GI, Miller IW: A reevaluation of the exclusion criteria used in antidepressant efficacy trials. Am J Psychiatry 159:191-200, 2002.
    • (2002) Am J Psychiatry , vol.159 , pp. 191-200
    • Posternak, M.A.1    Zimmerman, M.2    Keitner, G.I.3    Miller, I.W.4
  • 80
    • 1542290332 scopus 로고    scopus 로고
    • Does elimination of placebo responders in a placebo run-in increase the treatment effect in randomized clinical trials? A meta-analytic evaluation
    • Lee S, Walker JR, Jakul L, Sexton K: Does elimination of placebo responders in a placebo run-in increase the treatment effect in randomized clinical trials? A meta-analytic evaluation. Depress Anxiety 19:10-19, 2004.
    • (2004) Depress Anxiety , vol.19 , pp. 10-19
    • Lee, S.1    Walker, J.R.2    Jakul, L.3    Sexton, K.4
  • 81
    • 0035991243 scopus 로고    scopus 로고
    • Eicosapentaenoic acid and arachidonic acid: Collaboration and not antagonism is the key to biological understanding
    • Horrobin DF, Jenkins K, Bennett CN, Christie WW: Eicosapentaenoic acid and arachidonic acid: collaboration and not antagonism is the key to biological understanding. Prostaglandins Leukot Essent Fatty Acids 66:83-90, 2002.
    • (2002) Prostaglandins Leukot Essent Fatty Acids , vol.66 , pp. 83-90
    • Horrobin, D.F.1    Jenkins, K.2    Bennett, C.N.3    Christie, W.W.4
  • 82
    • 33746809138 scopus 로고    scopus 로고
    • Distribution, interconversion, and dose response of n-3 fatty acids in humans
    • Arterburn LM, Hall EB, Oken H: Distribution, interconversion, and dose response of n-3 fatty acids in humans. Am J Clin Nutr 83:1467S-1476S, 2006.
    • (2006) Am J Clin Nutr , vol.83 , pp. 1467S-1476S
    • Arterburn, L.M.1    Hall, E.B.2    Oken, H.3
  • 83
    • 0035883185 scopus 로고    scopus 로고
    • The relationship between age and the fatty acid composition of cerebral cortex and erythrocytes in human subjects
    • Carver JD, Benford VJ, Han B, Cantor AB: The relationship between age and the fatty acid composition of cerebral cortex and erythrocytes in human subjects. Brain Res Bull 56:79-85, 2001.
    • (2001) Brain Res Bull , vol.56 , pp. 79-85
    • Carver, J.D.1    Benford, V.J.2    Han, B.3    Cantor, A.B.4
  • 84
    • 0035062255 scopus 로고    scopus 로고
    • Docosahexaenoic acid supplementation-increased oxidative damage in bone marrow dna in aged rats and its relation to antioxidant vitamins
    • Umegaki K, Hashimoto M, Yamasaki H, Fujii Y, Yoshimura M, Sugisawa A, Shinozuka K: Docosahexaenoic acid supplementation-increased oxidative damage in bone marrow DNA in aged rats and its relation to antioxidant vitamins. Free Radic Res 34:427-435, 2001.
    • (2001) Free Radic Res , vol.34 , pp. 427-435
    • Umegaki, K.1    Hashimoto, M.2    Yamasaki, H.3    Fujii, Y.4    Yoshimura, M.5    Sugisawa, A.6    Shinozuka, K.7
  • 88
    • 23844549859 scopus 로고    scopus 로고
    • Compartmental modeling to quantify alpha-linolenic acid conversion after longer term intake of multiple tracer boluses
    • Goyens PL, Spilker ME, Zock PL, Katan MB, Mensink RP: Compartmental modeling to quantify alpha-linolenic acid conversion after longer term intake of multiple tracer boluses. J Lipid Res 46:1474-1483, 2005.
    • (2005) J Lipid Res , vol.46 , pp. 1474-1483
    • Goyens, P.L.1    Spilker, M.E.2    Zock, P.L.3    Katan, M.B.4    Mensink, R.P.5
  • 89
    • 36749082536 scopus 로고    scopus 로고
    • Brain metabolism of nutritionally essential polyunsaturated fatty acids depends on both the diet and the liver
    • Rapoport SI, Rao JS, Igarashi M: Brain metabolism of nutritionally essential polyunsaturated fatty acids depends on both the diet and the liver. Prostaglandins Leukot Essent Fatty Acids 77:251-261, 2007.
    • (2007) Prostaglandins Leukot Essent Fatty Acids , vol.77 , pp. 251-261
    • Rapoport, S.I.1    Rao, J.S.2    Igarashi, M.3
  • 90
    • 4744369972 scopus 로고    scopus 로고
    • Neuroprotective actions of eicosapentaenoic acid on lipopolysaccharideinduced dysfunction in rat hippocampus
    • Lonergan PE, Martin DS, Horrobin DF, Lynch MA: Neuroprotective actions of eicosapentaenoic acid on lipopolysaccharideinduced dysfunction in rat hippocampus. J Neurochem 91:20-29, 2004.
    • (2004) J Neurochem , vol.91 , pp. 20-29
    • Lonergan, P.E.1    Martin, D.S.2    Horrobin, D.F.3    Lynch, M.A.4
  • 91
    • 45549090724 scopus 로고    scopus 로고
    • Formation of highly reactive cyclopentenone isoprostane compounds (A3/j3-isoprostanes) in vivo from eicosapentaenoic acid
    • Brooks JD, Milne GL, Yin H, Sanchez SC, Porter NA, Morrow JD: Formation of highly reactive cyclopentenone isoprostane compounds (A3/J3-isoprostanes) in vivo from eicosapentaenoic acid. J Biol Chem 283:12043-12055, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 12043-12055
    • Brooks, J.D.1    Milne, G.L.2    Yin, H.3    Sanchez, S.C.4    Porter, N.A.5    Morrow, J.D.6
  • 92
    • 34447570317 scopus 로고    scopus 로고
    • Different ratios of eicosapentaenoic and docosahexaenoic omega-3 fatty acids in commercial fish oils differentially alter pro-inflammatory cytokines in peritoneal macrophages from c57bl/6 female mice
    • Bhattacharya A, Sun D, Rahman M, Fernandes G: Different ratios of eicosapentaenoic and docosahexaenoic omega-3 fatty acids in commercial fish oils differentially alter pro-inflammatory cytokines in peritoneal macrophages from C57BL/6 female mice. J Nutr Biochem 18:23-30, 2007.
    • (2007) J Nutr Biochem , vol.18 , pp. 23-30
    • Bhattacharya, A.1    Sun, D.2    Rahman, M.3    Fernandes, G.4
  • 93
    • 1042276587 scopus 로고    scopus 로고
    • Eicosapentaenoic acid prevents lps-induced tnf-alpha expression by preventing nfkappab activation
    • Zhao Y, Joshi-Barve S, Barve S, Chen LH: Eicosapentaenoic acid prevents LPS-induced TNF-alpha expression by preventing NFkappaB activation. J Am Coll Nutr 23:71-78, 2004.
    • (2004) J am Coll Nutr , vol.23 , pp. 71-78
    • Zhao, Y.1    Joshi-Barve, S.2    Barve, S.3    Chen, L.H.4
  • 94
    • 38749127987 scopus 로고    scopus 로고
    • Dietary eicosapentaenoic acid and docosahexaenoic acid equally incorporate as decosahexaenoic acid but differ in inflammatory effects
    • Sierra S, Lara-Villoslada F, Comalada M, Olivares M, Xaus J: Dietary eicosapentaenoic acid and docosahexaenoic acid equally incorporate as decosahexaenoic acid but differ in inflammatory effects. Nutrition 24:245-254, 2008.
    • (2008) Nutrition , vol.24 , pp. 245-254
    • Sierra, S.1    Lara-Villoslada, F.2    Comalada, M.3    Olivares, M.4    Xaus, J.5
  • 95
    • 37849018013 scopus 로고    scopus 로고
    • Why fish oils may not always be adequate treatments for depression or other inflammatory illnesses: Docosahexaenoic acid, an omega-3 polyunsaturated fatty acid, induces a th-1-like immune response
    • Maes M, Mihaylova I, Kubera M, Bosmans E: Why fish oils may not always be adequate treatments for depression or other inflammatory illnesses: docosahexaenoic acid, an omega-3 polyunsaturated fatty acid, induces a Th-1-like immune response. Neuro Endocrinol Lett 28:875-880, 2007.
    • (2007) Neuro Endocrinol Lett , vol.28 , pp. 875-880
    • Maes, M.1    Mihaylova, I.2    Kubera, M.3    Bosmans, E.4
  • 97
    • 34249089620 scopus 로고    scopus 로고
    • Seasonal dynamics of fatty acid content of a common food fish from the yenisei river, siberian grayling, thymallus arcticus
    • Nadezhda N, Sushchik MI, Kalachova G: Seasonal dynamics of fatty acid content of a common food fish from the Yenisei river, Siberian grayling, Thymallus arcticus. Food Chem 104:1353-1358, 2007.
    • (2007) Food Chem , vol.104 , pp. 1353-1358
    • Nadezhda, N.1    Sushchik, M.I.2    Kalachova, G.3


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