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Volumn 3, Issue 4, 2004, Pages 445-464

A neural signaling triumvirate that influences ageing and age-related disease: Insulin/IGF-1, BDNF and serotonin

Author keywords

Autonomic nervous system; CREB; Hippocampus; Hypothalamus; PI3 kinase; Stress response

Indexed keywords

ANTIOXIDANT; BRAIN DERIVED NEUROTROPHIC FACTOR; CITALOPRAM; INSULIN; PAROXETINE; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; SOMATOMEDIN C; THIOCTIC ACID;

EID: 8444250215     PISSN: 15681637     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arr.2004.08.001     Document Type: Short Survey
Times cited : (232)

References (113)
  • 1
    • 0037204590 scopus 로고    scopus 로고
    • Insulin-like growth factor-I and neurogenesis in the adult mammalian brain
    • M.F. Anderson, M.A. Aberg, M. Nilsson, and P.S. Eriksson Insulin-like growth factor-I and neurogenesis in the adult mammalian brain Dev. Brain Res. 134 2002 115 122
    • (2002) Dev. Brain Res. , vol.134 , pp. 115-122
    • Anderson, M.F.1    Aberg, M.A.2    Nilsson, M.3    Eriksson, P.S.4
  • 2
    • 0038623652 scopus 로고    scopus 로고
    • Intermittent fasting disociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake
    • R.M. Anson, Z. Guo, R. de Cabo, T. Iyun, M. Rios, A. Hagepanos, D.K. Ingram, M.A. Lane, and M.P. Mattson Intermittent fasting disociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake Proc. Natl. Acad. Sci. U.S.A. 100 2003 6216 6220
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 6216-6220
    • Anson, R.M.1    Guo, Z.2    De Cabo, R.3    Iyun, T.4    Rios, M.5    Hagepanos, A.6    Ingram, D.K.7    Lane, M.A.8    Mattson, M.P.9
  • 3
    • 0038476369 scopus 로고    scopus 로고
    • Neurochemical changes related to ageing in the rat brain and the effect of DL-alpha-lipoic acid
    • P. Arivazhagan, and C. Panneerselvam Neurochemical changes related to ageing in the rat brain and the effect of DL-alpha-lipoic acid Exp. Gerontol. 37 2002 1489 1494
    • (2002) Exp. Gerontol. , vol.37 , pp. 1489-1494
    • Arivazhagan, P.1    Panneerselvam, C.2
  • 4
    • 2442424380 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
    • Z. Arvanitakis, P.S. Wilson, J.L. Bienias, D.A. Evans, and D.A. Bennett Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function Arch. Neurol. 61 2004 661 666
    • (2004) Arch. Neurol. , vol.61 , pp. 661-666
    • Arvanitakis, Z.1    Wilson, P.S.2    Bienias, J.L.3    Evans, D.A.4    Bennett, D.A.5
  • 5
    • 0035891886 scopus 로고    scopus 로고
    • Modern views on an ancient chemical: Serotonin effects on cell proliferation, maturation, and apoptosis
    • E.C. Azmitia Modern views on an ancient chemical: serotonin effects on cell proliferation, maturation, and apoptosis Brain Res. Bull. 56 2001 413 424
    • (2001) Brain Res. Bull. , vol.56 , pp. 413-424
    • Azmitia, E.C.1
  • 6
    • 0034771268 scopus 로고    scopus 로고
    • Exercise-induced changes in brain glucose and serotonin revealed by microdialysis in rat hippocampus: Effect of glucose supplementation
    • F. Bequet, D. Gomez-Merino, M. Berthelot, and C.Y. Guezennec Exercise-induced changes in brain glucose and serotonin revealed by microdialysis in rat hippocampus: effect of glucose supplementation Acta Physiol. Scand. 173 2001 223 230
    • (2001) Acta Physiol. Scand. , vol.173 , pp. 223-230
    • Bequet, F.1    Gomez-Merino, D.2    Berthelot, M.3    Guezennec, C.Y.4
  • 7
    • 0036917631 scopus 로고    scopus 로고
    • Serum insulin-like growth factor I regulates brain amyloid-beta levels
    • E. Carro, J.L. Trejo, T. Gomez-Isla, D. LeRoith, and I. Torres-Aleman Serum insulin-like growth factor I regulates brain amyloid-beta levels Nat. Med. 8 2002 1390 1397
    • (2002) Nat. Med. , vol.8 , pp. 1390-1397
    • Carro, E.1    Trejo, J.L.2    Gomez-Isla, T.3    Leroith, D.4    Torres-Aleman, I.5
  • 8
    • 0142195931 scopus 로고    scopus 로고
    • Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction
    • J. Chen, C.M. Astle, and D.E. Harrison Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction Exp. Hematol. 31 2003 1097 1103
    • (2003) Exp. Hematol. , vol.31 , pp. 1097-1103
    • Chen, J.1    Astle, C.M.2    Harrison, D.E.3
  • 9
    • 0026521942 scopus 로고
    • IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage
    • B. Cheng, and M.P. Mattson IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage J. Neurosci. 12 1992 1558 1566
    • (1992) J. Neurosci. , vol.12 , pp. 1558-1566
    • Cheng, B.1    Mattson, M.P.2
  • 10
    • 0028327218 scopus 로고
    • NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults
    • B. Cheng, and M.P. Mattson NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults Brain Res. 640 1994 56 67
    • (1994) Brain Res. , vol.640 , pp. 56-67
    • Cheng, B.1    Mattson, M.P.2
  • 11
    • 0037846129 scopus 로고    scopus 로고
    • A ketogenic diet increases brain insulin-like growth factor receptor and glucose transporter gene expression
    • C.M. Cheng, B. Kelley, J. Wang, D. Strauss, D.A. Eagles, and C.A. Bondy A ketogenic diet increases brain insulin-like growth factor receptor and glucose transporter gene expression Endocrinology 144 2003 2676 2682
    • (2003) Endocrinology , vol.144 , pp. 2676-2682
    • Cheng, C.M.1    Kelley, B.2    Wang, J.3    Strauss, D.4    Eagles, D.A.5    Bondy, C.A.6
  • 12
    • 0036602967 scopus 로고    scopus 로고
    • Exercise: A behavioral intervention to enhance brain health and plasticity
    • C.W. Cotman, and N.C. Berchtold Exercise: a behavioral intervention to enhance brain health and plasticity Trends Neurosci. 25 2002 295 301
    • (2002) Trends Neurosci. , vol.25 , pp. 295-301
    • Cotman, C.W.1    Berchtold, N.C.2
  • 14
    • 0036782071 scopus 로고    scopus 로고
    • Structural biology of insulin and IGF1 receptors: Implications for drug design
    • P. De Meyts, and J. Whittaker Structural biology of insulin and IGF1 receptors: implications for drug design Nat. Rev. Drug Discov. 1 2002 769 783
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 769-783
    • De Meyts, P.1    Whittaker, J.2
  • 15
    • 0035145760 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice
    • W. Duan, Z. Guo, and M.P. Mattson Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice J. Neurochem. 76 2001 619 626
    • (2001) J. Neurochem. , vol.76 , pp. 619-626
    • Duan, W.1    Guo, Z.2    Mattson, M.P.3
  • 16
    • 0037562083 scopus 로고    scopus 로고
    • Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain-derived neurotrophic factor
    • W. Duan, Z. Guo, H. Jiang, M. Ware, and M.P. Mattson Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain-derived neurotrophic factor Endocrinology 144 2003 2446 2453
    • (2003) Endocrinology , vol.144 , pp. 2446-2453
    • Duan, W.1    Guo, Z.2    Jiang, H.3    Ware, M.4    Mattson, M.P.5
  • 17
    • 0037418339 scopus 로고    scopus 로고
    • Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice
    • W. Duan, Z. Guo, H. Jiang, M. Ware, X.J. Li, and M.P. Mattson Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice Proc. Natl. Acad. Sci. U.S.A. 100 2003 2911 2916
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 2911-2916
    • Duan, W.1    Guo, Z.2    Jiang, H.3    Ware, M.4    Li, X.J.5    Mattson, M.P.6
  • 19
    • 0031681434 scopus 로고    scopus 로고
    • Novel therapeutic approaches beyond the serotonin receptor
    • R.S. Duman Novel therapeutic approaches beyond the serotonin receptor Biol. Psychiatry 44 1998 324 335
    • (1998) Biol. Psychiatry , vol.44 , pp. 324-335
    • Duman, R.S.1
  • 20
    • 0034946252 scopus 로고    scopus 로고
    • Physical fitness and changes in mortality: The survival of the fittest
    • G. Erikssen Physical fitness and changes in mortality: the survival of the fittest Sports Med. 31 2001 571 576
    • (2001) Sports Med. , vol.31 , pp. 571-576
    • Erikssen, G.1
  • 21
    • 0034595722 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in Huntington disease
    • I. Ferrer, E. Goutan, C. Marin, M.J. Rey, and T. Ribalta Brain-derived neurotrophic factor in Huntington disease Brain Res. 866 2000 257 261
    • (2000) Brain Res. , vol.866 , pp. 257-261
    • Ferrer, I.1    Goutan, E.2    Marin, C.3    Rey, M.J.4    Ribalta, T.5
  • 22
    • 0037469919 scopus 로고    scopus 로고
    • Assessment of autonomic function in high level athletes by pupillometry
    • J.A. Filipe Assessment of autonomic function in high level athletes by pupillometry Auton. Neurosci. 104 2003 66 72
    • (2003) Auton. Neurosci. , vol.104 , pp. 66-72
    • Filipe, J.A.1
  • 23
    • 0029610850 scopus 로고
    • Long-term effects of chronic social stress on serotonergic indices in the prefrontal cortex of adult male cynomolgus macaques
    • M.B. Fontenot, J.R. Kaplan, S.B. Manuck, V. Arango, and J.J. Mann Long-term effects of chronic social stress on serotonergic indices in the prefrontal cortex of adult male cynomolgus macaques Brain Res. 705 1995 105 108
    • (1995) Brain Res. , vol.705 , pp. 105-108
    • Fontenot, M.B.1    Kaplan, J.R.2    Manuck, S.B.3    Arango, V.4    Mann, J.J.5
  • 24
    • 0025947341 scopus 로고
    • Food intake and serum insulin responses to intraventricular infusions of insulin and IGF-I
    • L.A. Foster, N.K. Ames, and R.S. Emery Food intake and serum insulin responses to intraventricular infusions of insulin and IGF-I Physiol. Behav. 50 1991 745 749
    • (1991) Physiol. Behav. , vol.50 , pp. 745-749
    • Foster, L.A.1    Ames, N.K.2    Emery, R.S.3
  • 25
    • 2342606440 scopus 로고    scopus 로고
    • Learning at different satiation levels reveals parallel functions for the cAMP-protein kinase a cascade in long-term memory
    • A. Friedrich, U. Thomas, and U. Muller Learning at different satiation levels reveals parallel functions for the cAMP-protein kinase A cascade in long-term memory J. Neurosci. 24 2004 4460 4468
    • (2004) J. Neurosci. , vol.24 , pp. 4460-4468
    • Friedrich, A.1    Thomas, U.2    Muller, U.3
  • 26
    • 1842840805 scopus 로고    scopus 로고
    • Brain insulin and feeding: A bi-directional communication
    • K. Gerozissis Brain insulin and feeding: a bi-directional communication Eur. J. Pharmacol. 490 2004 59 70
    • (2004) Eur. J. Pharmacol. , vol.490 , pp. 59-70
    • Gerozissis, K.1
  • 27
    • 0028217132 scopus 로고
    • Requirement for BDNF in activity-dependent survival of cortical neurons
    • A. Ghosh Requirement for BDNF in activity-dependent survival of cortical neurons Science 263 1994 1618 1623
    • (1994) Science , vol.263 , pp. 1618-1623
    • Ghosh, A.1
  • 29
    • 0028901579 scopus 로고
    • Cortisol, ACTH, and cardiovascular response to a cognitive challenge paradigm in aging and depression
    • U. Gotthardt, U. Schweiger, J. Fahrenberg, C.J. Lauer, F. Holsboer, and I. Heuser Cortisol, ACTH, and cardiovascular response to a cognitive challenge paradigm in aging and depression Am. J. Physiol. 268 1995 R865 R873
    • (1995) Am. J. Physiol. , vol.268
    • Gotthardt, U.1    Schweiger, U.2    Fahrenberg, J.3    Lauer, C.J.4    Holsboer, F.5    Heuser, I.6
  • 30
    • 0141956456 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 and post-ischemic brain injury
    • J. Guan, L. Bennet, P.D. Gluckman, and A.J. Gunn Insulin-like growth factor-1 and post-ischemic brain injury Prog. Neurobiol. 70 2003 443 462
    • (2003) Prog. Neurobiol. , vol.70 , pp. 443-462
    • Guan, J.1    Bennet, L.2    Gluckman, P.D.3    Gunn, A.J.4
  • 31
    • 0035834343 scopus 로고    scopus 로고
    • Changes in BDNF-immunoreactive structures in the hippocampal formation of the aged macaque monkey
    • M. Hayashi, F. Mistunaga, K. Ohira, and K. Shimizu Changes in BDNF-immunoreactive structures in the hippocampal formation of the aged macaque monkey Brain Res. 918 2001 191 196
    • (2001) Brain Res. , vol.918 , pp. 191-196
    • Hayashi, M.1    Mistunaga, F.2    Ohira, K.3    Shimizu, K.4
  • 32
    • 0242683909 scopus 로고    scopus 로고
    • Knockout corner: Neurobehavioural consequences of a serotonin 5-HT(2C) receptor gene mutation
    • L.K. Heisler, and L.H. Tecott Knockout corner: neurobehavioural consequences of a serotonin 5-HT(2C) receptor gene mutation Int. J. Neuropsychopharmcol. 2 1999 67 69
    • (1999) Int. J. Neuropsychopharmcol. , vol.2 , pp. 67-69
    • Heisler, L.K.1    Tecott, L.H.2
  • 33
    • 0037470539 scopus 로고    scopus 로고
    • Genetics and the specificity of the aging process
    • S. Hekimi, and L. Guarente Genetics and the specificity of the aging process Science 299 2003 1351 1354
    • (2003) Science , vol.299 , pp. 1351-1354
    • Hekimi, S.1    Guarente, L.2
  • 34
    • 0028859090 scopus 로고
    • Regulatory changes in neuroendocrine stress-integrative circuitry produced by a variable stress paradigm
    • J.P. Herman, D. Adams, and C. Prewitt Regulatory changes in neuroendocrine stress-integrative circuitry produced by a variable stress paradigm Neuroendocrinology 61 1995 180 190
    • (1995) Neuroendocrinology , vol.61 , pp. 180-190
    • Herman, J.P.1    Adams, D.2    Prewitt, C.3
  • 35
    • 0034087784 scopus 로고    scopus 로고
    • Region-specific neurotrophin imbalances in Alzheimer disease: Decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas
    • C. Hock, K. Heese, C. Hulette, C. Rosenberg, and U. Otten Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas Arch. Neurol. 57 2000 846 851
    • (2000) Arch. Neurol. , vol.57 , pp. 846-851
    • Hock, C.1    Heese, K.2    Hulette, C.3    Rosenberg, C.4    Otten, U.5
  • 38
    • 0141642251 scopus 로고    scopus 로고
    • Attenuated 5-HT1A receptor signaling in brains of suicide victims: Involvement of adenylyl cyclase, phosphatidylinositol 3-kinase, Akt and mitogen-activated protein kinase
    • S.C. Hsiung, M. Aldersberg, V. Arango, J.J. Mann, H. Tamir, and K.P. Liu Attenuated 5-HT1A receptor signaling in brains of suicide victims: involvement of adenylyl cyclase, phosphatidylinositol 3-kinase, Akt and mitogen-activated protein kinase J. Neurochem. 87 2003 182 194
    • (2003) J. Neurochem. , vol.87 , pp. 182-194
    • Hsiung, S.C.1    Aldersberg, M.2    Arango, V.3    Mann, J.J.4    Tamir, H.5    Liu, K.P.6
  • 39
    • 0041488911 scopus 로고    scopus 로고
    • Trk receptors: Roles in neuronal signal transduction
    • E.J. Huang, and L.F. Reichardt Trk receptors: Roles in neuronal signal transduction Annu. Rev. Biochem. 72 2003 609 642
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 609-642
    • Huang, E.J.1    Reichardt, L.F.2
  • 40
    • 0034769530 scopus 로고    scopus 로고
    • Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans
    • T.E. Johnson, E. de Castro, S. Hegi de Castro, J. Cypser, S. Hendersen, and P. Tedesco Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans Exp. Gerontol. 36 2001 1609 1617
    • (2001) Exp. Gerontol. , vol.36 , pp. 1609-1617
    • Johnson, T.E.1    De Castro, E.2    Hegi De Castro, S.3    Cypser, J.4    Hendersen, S.5    Tedesco, P.6
  • 41
    • 0027376801 scopus 로고
    • Socioeconomic factors and cardiovascular disease: A review of the literature
    • G.A. Kaplan, and J.E. Keil Socioeconomic factors and cardiovascular disease: a review of the literature Circulation. 88 1993 973 978
    • (1993) Circulation. , vol.88 , pp. 973-978
    • Kaplan, G.A.1    Keil, J.E.2
  • 42
    • 1642546276 scopus 로고    scopus 로고
    • Oxidative damage and major depression: The potential antioxidant action of selective serotonin re-uptake inhibitors
    • S.D. Khanzode, G.N. Dakhale, S.S. Khanzode, A. Saoji, and R. Plasodkar Oxidative damage and major depression: the potential antioxidant action of selective serotonin re-uptake inhibitors Redox Rep. 8 2003 365 370
    • (2003) Redox Rep. , vol.8 , pp. 365-370
    • Khanzode, S.D.1    Dakhale, G.N.2    Khanzode, S.S.3    Saoji, A.4    Plasodkar, R.5
  • 46
    • 0034617440 scopus 로고    scopus 로고
    • Reduced expression of insulin-like growth factor 1 messenger RNA in the hippocampus of aged rats
    • M. Lai, C.J. Hibbard, P.D. Gluckman, and J.R. Seckl Reduced expression of insulin-like growth factor 1 messenger RNA in the hippocampus of aged rats Neurosci. Lett. 288 2000 66 70
    • (2000) Neurosci. Lett. , vol.288 , pp. 66-70
    • Lai, M.1    Hibbard, C.J.2    Gluckman, P.D.3    Seckl, J.R.4
  • 47
    • 0035108619 scopus 로고    scopus 로고
    • Activation of 5-HT receptors that stimulate the adenylyl cyclase pathway positively regulates IGF-I in cultured craniofacial mesenchymal cells
    • H.W. Lambert, E.R. Weiss, and J.M. Lauder Activation of 5-HT receptors that stimulate the adenylyl cyclase pathway positively regulates IGF-I in cultured craniofacial mesenchymal cells Dev. Neurosci. 23 2001 70 77
    • (2001) Dev. Neurosci. , vol.23 , pp. 70-77
    • Lambert, H.W.1    Weiss, E.R.2    Lauder, J.M.3
  • 48
    • 0027521498 scopus 로고
    • Fluoxetine induced insulin-like growth factor II (IGF-II) changes in hypothalami of normal, exercised and food restricted rats
    • T.J. Lauterio, T.S. Rieg, I. Ahmed, and P.F. Aravich Fluoxetine induced insulin-like growth factor II (IGF-II) changes in hypothalami of normal, exercised and food restricted rats Regul. Pept. 48 1993 21 28
    • (1993) Regul. Pept. , vol.48 , pp. 21-28
    • Lauterio, T.J.1    Rieg, T.S.2    Ahmed, I.3    Aravich, P.F.4
  • 49
    • 0032950280 scopus 로고    scopus 로고
    • Insulin-like growth factor-I (IGF-I) ameliorates and IGF binding protein-1 (IGFBP-1) exacerbates the effects of undernutrition on brain growth during early postnatal life: Studies in IGF-I and IGFBP-1 transgenic mice
    • K.H. Lee, A.S. Calikoglu, P. Ye, and A.J. D'Ercole Insulin-like growth factor-I (IGF-I) ameliorates and IGF binding protein-1 (IGFBP-1) exacerbates the effects of undernutrition on brain growth during early postnatal life: studies in IGF-I and IGFBP-1 transgenic mice Pediatr. Res. 45 1999 331 336
    • (1999) Pediatr. Res. , vol.45 , pp. 331-336
    • Lee, K.H.1    Calikoglu, A.S.2    Ye, P.3    D'Ercole, A.J.4
  • 50
    • 0033664205 scopus 로고    scopus 로고
    • Dietary restriction selectively decreases glucocorticoid receptor expression in the hippocampus and cerebral cortex of rats
    • J. Lee, J.P. Herman, and M.P. Mattson Dietary restriction selectively decreases glucocorticoid receptor expression in the hippocampus and cerebral cortex of rats Exp. Neurol. 166 2000 435 441
    • (2000) Exp. Neurol. , vol.166 , pp. 435-441
    • Lee, J.1    Herman, J.P.2    Mattson, M.P.3
  • 51
    • 0036734833 scopus 로고    scopus 로고
    • Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhanement of neurogenesis by dietary restriction in the hippocampus of adult mice
    • J. Lee, W. Duan, and M.P. Mattson Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhanement of neurogenesis by dietary restriction in the hippocampus of adult mice J. Neurochem. 82 2002 1367 1375
    • (2002) J. Neurochem. , vol.82 , pp. 1367-1375
    • Lee, J.1    Duan, W.2    Mattson, M.P.3
  • 53
    • 0345447590 scopus 로고    scopus 로고
    • Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan
    • N. Libina, J.R. Berman, and C. Kenyon Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan Cell 115 2003 489 502
    • (2003) Cell , vol.115 , pp. 489-502
    • Libina, N.1    Berman, J.R.2    Kenyon, C.3
  • 54
    • 0028262267 scopus 로고
    • Neurotrophic growth factors and neurodegenerative diseases: Therapeutic potential of the neurotrophins and ciliary neurotrophic factor
    • R.M. Lindsay Neurotrophic growth factors and neurodegenerative diseases: therapeutic potential of the neurotrophins and ciliary neurotrophic factor Neurobiol. Aging. 15 1994 249 251
    • (1994) Neurobiol. Aging. , vol.15 , pp. 249-251
    • Lindsay, R.M.1
  • 55
    • 0026599302 scopus 로고
    • Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma
    • O. Lindvall, P. Ernfors, J. Bengzon, Z. Kokaia, M.L. Smith, B.K. Siesjo, and H. Persson Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma Proc. Natl. Acad. Sci. U.S.A. 89 1992 648 652
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 648-652
    • Lindvall, O.1    Ernfors, P.2    Bengzon, J.3    Kokaia, Z.4    Smith, M.L.5    Siesjo, B.K.6    Persson, H.7
  • 58
    • 0036304650 scopus 로고    scopus 로고
    • Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior
    • M.P. Mattson, S.L. Chan, and W. Duan Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior Physiol. Rev. 82 2002 637 672
    • (2002) Physiol. Rev. , vol.82 , pp. 637-672
    • Mattson, M.P.1    Chan, S.L.2    Duan, W.3
  • 59
    • 0036752591 scopus 로고    scopus 로고
    • Sex, stress and the hippocampus: Allostasis, allostatic load and the aging process
    • B.S. McEwen Sex, stress and the hippocampus: allostasis, allostatic load and the aging process Neurobiol. Aging 23 2002 921 939
    • (2002) Neurobiol. Aging , vol.23 , pp. 921-939
    • McEwen, B.S.1
  • 60
    • 0041976018 scopus 로고    scopus 로고
    • 5-HT2A receptor activation leads to increased BDNF mRNA expression in C6 glioma cells
    • R. Meller, J.M. Babity, and D.G. Grahame-Smith 5-HT2A receptor activation leads to increased BDNF mRNA expression in C6 glioma cells Neuromolecular Med. 1 2002 197 205
    • (2002) Neuromolecular Med. , vol.1 , pp. 197-205
    • Meller, R.1    Babity, J.M.2    Grahame-Smith, D.G.3
  • 62
    • 0030993317 scopus 로고    scopus 로고
    • The serotonergic and noradrenergic systems of the hippocampus: Their interactions and the effects of antidepressant treatments
    • R. Mongeau, P. Blier, and C. de Montigny The serotonergic and noradrenergic systems of the hippocampus: their interactions and the effects of antidepressant treatments Brain Res. Rev. 23 1997 145 195
    • (1997) Brain Res. Rev. , vol.23 , pp. 145-195
    • Mongeau, R.1    Blier, P.2    De Montigny, C.3
  • 63
    • 0023095333 scopus 로고
    • Dopamine and serotonin systems in human and rodent brain: Effects of age and neurodegenerative disease
    • D.G. Morgan, P.C. May, and C.E. Finch Dopamine and serotonin systems in human and rodent brain: effects of age and neurodegenerative disease J. Am. Geriatr. Soc. 35 1987 334 345
    • (1987) J. Am. Geriatr. Soc. , vol.35 , pp. 334-345
    • Morgan, D.G.1    May, P.C.2    Finch, C.E.3
  • 64
    • 0034177790 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine1A receptor/Giβγ stimulates mitogen-activated protein kinase via NAD(P)H oxidase and reactive oxygen species upstream of Src in Chinese hamster ovary cells
    • Y.V. Mukhin, M.N. Garnovskaya, G. Collinsworth, J.S. Grewal, D. Pendergrass, T. Nagai, S. Pinckney, E.L. Greene, and J.R. Raymond 5-Hydroxytryptamine1A receptor/Giβγ stimulates mitogen-activated protein kinase via NAD(P)H oxidase and reactive oxygen species upstream of Src in Chinese hamster ovary cells Biochem. J. 347 2000 61 67
    • (2000) Biochem. J. , vol.347 , pp. 61-67
    • Mukhin, Y.V.1    Garnovskaya, M.N.2    Collinsworth, G.3    Grewal, J.S.4    Pendergrass, D.5    Nagai, T.6    Pinckney, S.7    Greene, E.L.8    Raymond, J.R.9
  • 66
    • 0034049930 scopus 로고    scopus 로고
    • Overexpression of insulin-like growth factor binding protein-1 in transgenic mice
    • L.J. Murphy Overexpression of insulin-like growth factor binding protein-1 in transgenic mice Pediatr. Nephrol. 14 2000 567 571
    • (2000) Pediatr. Nephrol. , vol.14 , pp. 567-571
    • Murphy, L.J.1
  • 67
    • 0037457059 scopus 로고    scopus 로고
    • IGF-1 activates p21 to inhibit UV-induced cell death
    • S.A. Murray, H. Zheng, L. Gu, and Z.X. Jim Xiao IGF-1 activates p21 to inhibit UV-induced cell death Oncogene 22 2003 1703 1711
    • (2003) Oncogene , vol.22 , pp. 1703-1711
    • Murray, S.A.1    Zheng, H.2    Gu, L.3    Jim Xiao, Z.X.4
  • 70
    • 0842346700 scopus 로고    scopus 로고
    • Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and beta-adrenergic response in ventricular myocytes
    • F.L. Norby, N.S. Aberle, J. Kajstura, P. Anversa, and J. Ren Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and beta-adrenergic response in ventricular myocytes J. Endocrinol. 180 2004 175 182
    • (2004) J. Endocrinol. , vol.180 , pp. 175-182
    • Norby, F.L.1    Aberle, N.S.2    Kajstura, J.3    Anversa, P.4    Ren, J.5
  • 72
    • 0036267472 scopus 로고    scopus 로고
    • Decreasing hypothalmic insulin receptors cause hyperphagia and insulin resistance in rats
    • S. Obici, Z. Feng, G. Karkanias, D.G. Baskin, and L. Rossetti Decreasing hypothalmic insulin receptors cause hyperphagia and insulin resistance in rats Nat. Neurosci. 5 2002 566 572
    • (2002) Nat. Neurosci. , vol.5 , pp. 566-572
    • Obici, S.1    Feng, Z.2    Karkanias, G.3    Baskin, D.G.4    Rossetti, L.5
  • 73
    • 0033787726 scopus 로고    scopus 로고
    • Insulin resistance in patients with depression and its changes during the clinical course of depression: Minimal model analysis
    • F. Okamura, A. Tashiro, A. Utumu, T. Imai, T. Suchi, D. Tamura, Y. Sato, S. Suzuki, and M. Hongo Insulin resistance in patients with depression and its changes during the clinical course of depression: minimal model analysis Metabolism. 49 2000 1255 1260
    • (2000) Metabolism. , vol.49 , pp. 1255-1260
    • Okamura, F.1    Tashiro, A.2    Utumu, A.3    Imai, T.4    Suchi, T.5    Tamura, D.6    Sato, Y.7    Suzuki, S.8    Hongo, M.9
  • 74
    • 2942752141 scopus 로고    scopus 로고
    • Quality of life and metabolic status in mildly depressed women with type 2 diabetes treated with paroxetine: A single-blind randomised placebo controlled trial
    • M. Paile-Hyvarinen, K. Wahlbeck, and J.G. Eriksson Quality of life and metabolic status in mildly depressed women with type 2 diabetes treated with paroxetine: a single-blind randomised placebo controlled trial BMC Fam. Pract. 4 2003 7
    • (2003) BMC Fam. Pract. , vol.4 , pp. 7
    • Paile-Hyvarinen, M.1    Wahlbeck, K.2    Eriksson, J.G.3
  • 75
    • 0036752023 scopus 로고    scopus 로고
    • The glucocorticoid paradox of caloric restriction in slowing brain aging
    • N.V. Patel, and C.E. Finch The glucocorticoid paradox of caloric restriction in slowing brain aging Neurobiol. Aging 23 2002 707 717
    • (2002) Neurobiol. Aging , vol.23 , pp. 707-717
    • Patel, N.V.1    Finch, C.E.2
  • 77
  • 78
    • 0036827963 scopus 로고    scopus 로고
    • Activation of extracellular-regulated kinase by 5-hydroxytryptamine receptors in PC12 cells is protein kinase C-independent and requires calmodulin and tyrosine kinases
    • J.C. Quinn, N.N. Johnson-Farley, J. Yoon, and D.S. Cowen Activation of extracellular-regulated kinase by 5-hydroxytryptamine receptors in PC12 cells is protein kinase C-independent and requires calmodulin and tyrosine kinases J. Pharmacol. Exp. Ther. 303 2002 746 752
    • (2002) J. Pharmacol. Exp. Ther. , vol.303 , pp. 746-752
    • Quinn, J.C.1    Johnson-Farley, N.N.2    Yoon, J.3    Cowen, D.S.4
  • 79
    • 0033380583 scopus 로고    scopus 로고
    • Neurological changes induced by stress in streptozotocin diabetic rats
    • L.P. Reagan, A.M. Magarinos, and B.S. McEwen Neurological changes induced by stress in streptozotocin diabetic rats Ann. N.Y. Acad. Sci. 893 1999 126 137
    • (1999) Ann. N.Y. Acad. Sci. , vol.893 , pp. 126-137
    • Reagan, L.P.1    Magarinos, A.M.2    McEwen, B.S.3
  • 80
    • 2342430250 scopus 로고    scopus 로고
    • Obesity, insulin resistance, and cardiovascular disease
    • G. Reaven, F. Abbasi, and T. McLaughlin Obesity, insulin resistance, and cardiovascular disease Recent Prog. Horm. Res. 59 2004 207 223
    • (2004) Recent Prog. Horm. Res. , vol.59 , pp. 207-223
    • Reaven, G.1    Abbasi, F.2    McLaughlin, T.3
  • 81
    • 0030483754 scopus 로고    scopus 로고
    • Neurochemical modulation of the hippocampus in learning, remembering and forgetting in primates
    • R.M. Ridley, J.A. Harder, and H.F. Baker Neurochemical modulation of the hippocampus in learning, remembering and forgetting in primates Neurodegeneration 5 1996 467 471
    • (1996) Neurodegeneration , vol.5 , pp. 467-471
    • Ridley, R.M.1    Harder, J.A.2    Baker, H.F.3
  • 82
    • 0034792085 scopus 로고    scopus 로고
    • Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity
    • M. Rios, G. Fan, C. Fekete, J. Kelly, B. Bates, R. Kuehn, R.M. Lechan, and R. Jaenisch Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity Mol. Endocrinol. 15 2001 1748 1757
    • (2001) Mol. Endocrinol. , vol.15 , pp. 1748-1757
    • Rios, M.1    Fan, G.2    Fekete, C.3    Kelly, J.4    Bates, B.5    Kuehn, R.6    Lechan, R.M.7    Jaenisch, R.8
  • 83
    • 0034698096 scopus 로고    scopus 로고
    • Transactivation of the EGF receptor mediates IGF-1-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells
    • F.L. Roudabush, K.L. Pierce, S. Maudsley, K.D. Khan, and L.M. Luttrell Transactivation of the EGF receptor mediates IGF-1-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells J. Biol. Chem. 275 2000 22583 22589
    • (2000) J. Biol. Chem. , vol.275 , pp. 22583-22589
    • Roudabush, F.L.1    Pierce, K.L.2    Maudsley, S.3    Khan, K.D.4    Luttrell, L.M.5
  • 84
    • 0037563890 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor, behavior, and new directions for the treatment of mental disorders
    • A. Russo-Neustadt Brain-derived neurotrophic factor, behavior, and new directions for the treatment of mental disorders Semin. Clin. Neuropsychiatry 8 2003 109 118
    • (2003) Semin. Clin. Neuropsychiatry , vol.8 , pp. 109-118
    • Russo-Neustadt, A.1
  • 85
    • 0035899867 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors and myocardial infarction
    • W.H. Sauer, J.A. Berlin, and S.E. Kimmel Selective serotonin reuptake inhibitors and myocardial infarction Circulation 104 2002 1894 1898
    • (2002) Circulation , vol.104 , pp. 1894-1898
    • Sauer, W.H.1    Berlin, J.A.2    Kimmel, S.E.3
  • 86
  • 87
    • 0036086818 scopus 로고    scopus 로고
    • Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model
    • I. Shimokawa, Y. Higami, M. Utsuyama, T. Tuchiya, T. Komatsu, T. Chiba, and H. Yamaza Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model Am. J. Pathol. 160 2002 2259 2265
    • (2002) Am. J. Pathol. , vol.160 , pp. 2259-2265
    • Shimokawa, I.1    Higami, Y.2    Utsuyama, M.3    Tuchiya, T.4    Komatsu, T.5    Chiba, T.6    Yamaza, H.7
  • 88
    • 7144227374 scopus 로고    scopus 로고
    • Serotonergic control of the organization of feeding and satiety
    • K.J. Simansky Serotonergic control of the organization of feeding and satiety Behav. Brain Res. 73 1996 37 42
    • (1996) Behav. Brain Res. , vol.73 , pp. 37-42
    • Simansky, K.J.1
  • 89
    • 0029925352 scopus 로고    scopus 로고
    • BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration
    • J.A. Siuciak, C. Boylan, M. Fritsche, C.A. Altar, and R.M. Lindsay BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration Brain Res. 710 1996 11 20
    • (1996) Brain Res. , vol.710 , pp. 11-20
    • Siuciak, J.A.1    Boylan, C.2    Fritsche, M.3    Altar, C.A.4    Lindsay, R.M.5
  • 90
    • 0030066467 scopus 로고    scopus 로고
    • Linguistic ability in early life and cognitive function and Alzheimer's disease in late life: Findings from the Nun study
    • D.A. Snowdon, S.J. Kemper, J.A. Mortimer, L.H. Greiner, D.R. Wekstein, and W.R. Markesbery Linguistic ability in early life and cognitive function and Alzheimer's disease in late life: findings from the Nun study JAMA 275 1996 528 532
    • (1996) JAMA , vol.275 , pp. 528-532
    • Snowdon, D.A.1    Kemper, S.J.2    Mortimer, J.A.3    Greiner, L.H.4    Wekstein, D.R.5    Markesbery, W.R.6
  • 92
    • 1542286877 scopus 로고    scopus 로고
    • Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism
    • T.L. Spires, H.E. Grote, N.K. Varshney, P.M. Cordery, A. van Dellen, C. Blakemore, and A.J. Hannan Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism J. Neurosci. 24 2004 2270 2276
    • (2004) J. Neurosci. , vol.24 , pp. 2270-2276
    • Spires, T.L.1    Grote, H.E.2    Varshney, N.K.3    Cordery, P.M.4    Van Dellen, A.5    Blakemore, C.6    Hannan, A.J.7
  • 93
    • 0037605948 scopus 로고    scopus 로고
    • Education and the association between vascular risk factors and cognitive function: A cross-sectional study in older Koreans with cognitive impairment
    • R. Stewart, J.M. Kim, I.S. Shin, and J.S. Yoon Education and the association between vascular risk factors and cognitive function: a cross-sectional study in older Koreans with cognitive impairment Int. Psychogeriatr. 15 2003 27 36
    • (2003) Int. Psychogeriatr. , vol.15 , pp. 27-36
    • Stewart, R.1    Kim, J.M.2    Shin, I.S.3    Yoon, J.S.4
  • 94
    • 1542719300 scopus 로고    scopus 로고
    • Bupropion and paroxetine differentially influence cardiovascular and neuroendocrine responses to stress in depressed patients
    • P.A. Straneva-Meuse, K.C. Light, M.T. Allen, M. Golding, and S.S. Girdler Bupropion and paroxetine differentially influence cardiovascular and neuroendocrine responses to stress in depressed patients J. Affect. Disord. 79 2004 51 61
    • (2004) J. Affect. Disord. , vol.79 , pp. 51-61
    • Straneva-Meuse, P.A.1    Light, K.C.2    Allen, M.T.3    Golding, M.4    Girdler, S.S.5
  • 95
    • 0342680006 scopus 로고    scopus 로고
    • Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
    • J.Y. Sze, M. Victor, C. Loer, Y. Shi, and G. Ruvukun Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant Nature 403 2000 560 564
    • (2000) Nature , vol.403 , pp. 560-564
    • Sze, J.Y.1    Victor, M.2    Loer, C.3    Shi, Y.4    Ruvukun, G.5
  • 96
    • 0037470501 scopus 로고    scopus 로고
    • The endocrine regulation of aging by insulin-like signals
    • M. Tatar, A. Bartke, and A. Antebi The endocrine regulation of aging by insulin-like signals Science 299 2003 1346 1351
    • (2003) Science , vol.299 , pp. 1346-1351
    • Tatar, M.1    Bartke, A.2    Antebi, A.3
  • 98
    • 0024283980 scopus 로고
    • Insulin found at last?
    • A. Thorpe, and H. Duve Insulin found at last? Nature 331 1988 483 484
    • (1988) Nature , vol.331 , pp. 483-484
    • Thorpe, A.1    Duve, H.2
  • 99
    • 0032902685 scopus 로고    scopus 로고
    • Insulin-like growth factors as mediators of functional plasticity in the adult brain
    • I. Torres-Aleman Insulin-like growth factors as mediators of functional plasticity in the adult brain Horm. Metab Res. 31 1999 114 119
    • (1999) Horm. Metab Res. , vol.31 , pp. 114-119
    • Torres-Aleman, I.1
  • 100
    • 0141963353 scopus 로고    scopus 로고
    • The role of neurotransmitters in neurite outgrowth and synapse formation
    • R.E. Van Kesteren, and G.E. Spencer The role of neurotransmitters in neurite outgrowth and synapse formation Rev. Neurosci. 14 2003 217 231
    • (2003) Rev. Neurosci. , vol.14 , pp. 217-231
    • Van Kesteren, R.E.1    Spencer, G.E.2
  • 101
    • 0043268822 scopus 로고    scopus 로고
    • Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons
    • E. van Riel, O.C. Meijer, P.J. Steenbergen, and M. Joels Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons Neuroscience 120 2003 649 658
    • (2003) Neuroscience , vol.120 , pp. 649-658
    • Van Riel, E.1    Meijer, O.C.2    Steenbergen, P.J.3    Joels, M.4
  • 102
    • 0037639031 scopus 로고    scopus 로고
    • Intermittent food deprivation improves cardiovascular and neuroendocrine responses to stress in rats
    • R. Wan, S. Camandola, and M.P. Mattson Intermittent food deprivation improves cardiovascular and neuroendocrine responses to stress in rats J. Nutr. 133 2003 1921 1929
    • (2003) J. Nutr. , vol.133 , pp. 1921-1929
    • Wan, R.1    Camandola, S.2    Mattson, M.P.3
  • 103
    • 0031043890 scopus 로고    scopus 로고
    • Serotonergic modulation of behaviour: A phylogenetic overview
    • W.A. Weiger Serotonergic modulation of behaviour: a phylogenetic overview Biol. Rev. Camb. Philos. Soc. 72 1997 61 95
    • (1997) Biol. Rev. Camb. Philos. Soc. , vol.72 , pp. 61-95
    • Weiger, W.A.1
  • 104
    • 0031549576 scopus 로고    scopus 로고
    • Seminars in medicine of the Beth Israel deaconess medical center. Caloric intake and aging
    • R. Weindruch, and R.S. Sohal Seminars in medicine of the Beth Israel deaconess medical center. Caloric intake and aging N. Engl. J. Med. 337 1997 986 994
    • (1997) N. Engl. J. Med. , vol.337 , pp. 986-994
    • Weindruch, R.1    Sohal, R.S.2
  • 105
    • 0027666093 scopus 로고
    • Exercise training and dietary carbohydrate effects on selected hormones and thermic effect of feeding
    • K.A. Witt, J.T. Snook, T.M. O'Dorisio, D. Zivony, and W.B. Malarkey Exercise training and dietary carbohydrate effects on selected hormones and thermic effect of feeding Int. J. Sport Nutr. 3 1993 272 289
    • (1993) Int. J. Sport Nutr. , vol.3 , pp. 272-289
    • Witt, K.A.1    Snook, J.T.2    O'Dorisio, T.M.3    Zivony, D.4    Malarkey, W.B.5
  • 106
    • 0036542955 scopus 로고    scopus 로고
    • Life span: Getting the signal from the nervous system
    • C.A. Wolkow Life span: getting the signal from the nervous system Trends Neurosci. 25 2002 212 216
    • (2002) Trends Neurosci. , vol.25 , pp. 212-216
    • Wolkow, C.A.1
  • 107
    • 0034613164 scopus 로고    scopus 로고
    • Regulation of C. elegans life-span by insulin like signaling in the nervous system
    • C.A. Wolkow, K.D. Kimura, M.S. Lee, and G. Ruvkun Regulation of C. elegans life-span by insulin like signaling in the nervous system Science 290 2000 147 150
    • (2000) Science , vol.290 , pp. 147-150
    • Wolkow, C.A.1    Kimura, K.D.2    Lee, M.S.3    Ruvkun, G.4
  • 109
    • 0030856143 scopus 로고    scopus 로고
    • Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons
    • M. Yamada, H. Ohnishi, S. Sano, A. Nakatani, T. Ikeuchi, and H. Hatanaka Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons J. Biol. Chem. 272 1997 30334 30339
    • (1997) J. Biol. Chem. , vol.272 , pp. 30334-30339
    • Yamada, M.1    Ohnishi, H.2    Sano, S.3    Nakatani, A.4    Ikeuchi, T.5    Hatanaka, H.6
  • 110
    • 0032957382 scopus 로고    scopus 로고
    • Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective
    • D. Young, P.A. Lawlor, P. Leone, M. Dragunow, and M.J. During Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective Nat. Med. 5 1999 448 453
    • (1999) Nat. Med. , vol.5 , pp. 448-453
    • Young, D.1    Lawlor, P.A.2    Leone, P.3    Dragunow, M.4    During, M.J.5
  • 111
    • 0035040692 scopus 로고    scopus 로고
    • Stress resistance by caloric restriction for longevity
    • B.P. Yu, and H.Y. Chung Stress resistance by caloric restriction for longevity Ann. N.Y. Acad. Sci. 928 2001 39 47
    • (2001) Ann. N.Y. Acad. Sci. , vol.928 , pp. 39-47
    • Yu, B.P.1    Chung, H.Y.2
  • 112
    • 0001611514 scopus 로고    scopus 로고
    • Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: Evidence for a preconditioning mechanism
    • Z.F. Yu, and M.P. Mattson Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism J. Neurosci. Res. 57 1999 830 839
    • (1999) J. Neurosci. Res. , vol.57 , pp. 830-839
    • Yu, Z.F.1    Mattson, M.P.2
  • 113
    • 1842633872 scopus 로고    scopus 로고
    • Insulin and the insulin receptor in experimental models of learning and memory
    • W.Q. Zhao, H. Cheng, M.J. Quon, and D.L. Alkon Insulin and the insulin receptor in experimental models of learning and memory Eur. J. Pharmacol. 490 2004 71 81
    • (2004) Eur. J. Pharmacol. , vol.490 , pp. 71-81
    • Zhao, W.Q.1    Cheng, H.2    Quon, M.J.3    Alkon, D.L.4


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