-
1
-
-
34047190259
-
Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting
-
D. De Paula, M.V. Bentley, and R.I. Mahato. Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting. RNA. 13:431-456 (2007)
-
(2007)
RNA
, vol.13
, pp. 431-456
-
-
De Paula, D.1
Bentley, M.V.2
Mahato, R.I.3
-
2
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 411:494-498 (2001)
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
3
-
-
0033615491
-
A species of small antisense RNA in posttranscriptional gene silencing in plants
-
A.J. HamiltonD.C. Baulcombe. A species of small antisense RNA in posttranscriptional gene silencing in plants. Science. 286:950-952 (1999)
-
(1999)
Science
, vol.286
, pp. 950-952
-
-
Hamilton, A.J.1
Baulcombe, D.C.2
-
5
-
-
3242677639
-
siRNAs: Applications in functional genomics and potential as therapeutics
-
Y. DorsettT. Tuschl. siRNAs: applications in functional genomics and potential as therapeutics. Nat Rev Drug Discov. 3:318-329 (2004)
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 318-329
-
-
Dorsett, Y.1
Tuschl, T.2
-
6
-
-
34547228805
-
Polymer-based siRNA delivery: Perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery
-
D.J. Gary, N. Puri, and Y.Y. Won. Polymer-based siRNA delivery: perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery. J Control Release. 121:64-73 (2007)
-
(2007)
J Control Release
, vol.121
, pp. 64-73
-
-
Gary, D.J.1
Puri, N.2
Won, Y.Y.3
-
8
-
-
33845216721
-
PEG conjugated VEGF siRNA for anti-angiogenic gene therapy
-
S.H. Kim, J.H. Jeong, S.H. Lee, S.W. Kim, and T.G. Park. PEG conjugated VEGF siRNA for anti-angiogenic gene therapy. J Control Release. 116:123-129 (2006)
-
(2006)
J Control Release
, vol.116
, pp. 123-129
-
-
Kim, S.H.1
Jeong, J.H.2
Lee, S.H.3
Kim, S.W.4
Park, T.G.5
-
9
-
-
4444220551
-
Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells
-
C. Lorenz, P. Hadwiger, M. John, H.P. Vornlocher, and C. Unverzagt. Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells. Bioorg Med Chem Lett. 14:4975-4977 (2004)
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 4975-4977
-
-
Lorenz, C.1
Hadwiger, P.2
John, M.3
Vornlocher, H.P.4
Unverzagt, C.5
-
10
-
-
34648834877
-
Lung delivery studies using siRNA conjugated to TAT(48-60) and penetratin reveal peptide induced reduction in gene expression and induction of innate immunity
-
S.A. Moschos, S.W. Jones, M.M. Perry, A.E. Williams, J.S. Erjefalt, J.J. Turner, P.J. Barnes, B.S. Sproat, M.J. Gait, and M.A. Lindsay. Lung delivery studies using siRNA conjugated to TAT(48-60) and penetratin reveal peptide induced reduction in gene expression and induction of innate immunity. Bioconjug Chem. 18:1450-1459 (2007)
-
(2007)
Bioconjug Chem
, vol.18
, pp. 1450-1459
-
-
Moschos, S.A.1
Jones, S.W.2
Perry, M.M.3
Williams, A.E.4
Erjefalt, J.S.5
Turner, J.J.6
Barnes, P.J.7
Sproat, B.S.8
Gait, M.J.9
Lindsay, M.A.10
-
11
-
-
0842346326
-
Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells
-
A. MuratovskaM.R. Eccles. Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells. FEBS Lett. 558:63-68 (2004)
-
(2004)
FEBS Lett
, vol.558
, pp. 63-68
-
-
Muratovska, A.1
Eccles, M.R.2
-
12
-
-
41149179660
-
Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol
-
K. Nishina, T. Unno, Y. Uno, T. Kubodera, T. Kanouchi, H. Mizusawa, and T. Yokota. Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol. Mol Ther. 16:734-740 (2008)
-
(2008)
Mol Ther
, vol.16
, pp. 734-740
-
-
Nishina, K.1
Unno, T.2
Uno, Y.3
Kubodera, T.4
Kanouchi, T.5
Mizusawa, H.6
Yokota, T.7
-
13
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
J. Soutschek, A. Akinc, B. Bramlage, K. Charisse, R. Constien, M. Donoghue, S. Elbashir, A. Geick, P. Hadwiger, J. Harborth, M. John, V. Kesavan, G. Lavine, R.K. Pandey, T. Racie, K.G. Rajeev, I. Rohl, I. Toudjarska, G. Wang, S. Wuschko, D. Bumcrot, V. Koteliansky, S. Limmer, M. Manoharan, and H.P. Vornlocher. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature. 432:173-178 (2004)
-
(2004)
Nature
, vol.432
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
Charisse, K.4
Constien, R.5
Donoghue, M.6
Elbashir, S.7
Geick, A.8
Hadwiger, P.9
Harborth, J.10
John, M.11
Kesavan, V.12
Lavine, G.13
Pandey, R.K.14
Racie, T.15
Rajeev, K.G.16
Rohl, I.17
Toudjarska, I.18
Wang, G.19
Wuschko, S.20
Bumcrot, D.21
Koteliansky, V.22
Limmer, S.23
Manoharan, M.24
Vornlocher, H.P.25
more..
-
14
-
-
0001359591
-
Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans
-
C. Napoli, C. Lemieux, and R. Jorgensen. Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans. Plant Cell. 2:279-289 (1990)
-
(1990)
Plant Cell
, vol.2
, pp. 279-289
-
-
Napoli, C.1
Lemieux, C.2
Jorgensen, R.3
-
15
-
-
0025405838
-
Flavonoid genes in petunia: Addition of a limited number of gene copies may lead to a suppression of gene expression
-
A.R. van der Krol, L.A. Mur, M. Beld, J.N. Mol, and A.R. Stuitje. Flavonoid genes in petunia: addition of a limited number of gene copies may lead to a suppression of gene expression. Plant Cell. 2:291-299 (1990)
-
(1990)
Plant Cell
, vol.2
, pp. 291-299
-
-
Van Der Krol, A.R.1
Mur, L.A.2
Beld, M.3
Mol, J.N.4
Stuitje, A.R.5
-
16
-
-
0028031830
-
RNA-directed de novo methylation of genomic sequences in plants
-
M. Wassenegger, S. Heimes, L. Riedel, and H.L. Sanger. RNA-directed de novo methylation of genomic sequences in plants. Cell. 76:567-576 (1994)
-
(1994)
Cell
, vol.76
, pp. 567-576
-
-
Wassenegger, M.1
Heimes, S.2
Riedel, L.3
Sanger, H.L.4
-
17
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
A. Fire, S. Xu, M.K. Montgomery, S.A. Kostas, S.E. Driver, and C.C. Mello. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 391:806-811 (1998)
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
18
-
-
0030992349
-
A similarity between viral defense and gene silencing in plants
-
F. Ratcliff, B.D. Harrison, and D.C. Baulcombe. A similarity between viral defense and gene silencing in plants. Science. 276:1558-1560 (1997)
-
(1997)
Science
, vol.276
, pp. 1558-1560
-
-
Ratcliff, F.1
Harrison, B.D.2
Baulcombe, D.C.3
-
19
-
-
2342485506
-
miRNAs on the move: MiRNA biogenesis and the RNAi machinery
-
E.P. MurchisonG.J. Hannon. miRNAs on the move: miRNA biogenesis and the RNAi machinery. Curr Opin Cell Biol. 16:223-229 (2004)
-
(2004)
Curr Opin Cell Biol
, vol.16
, pp. 223-229
-
-
Murchison, E.P.1
Hannon, G.J.2
-
20
-
-
24644446398
-
Ribo-gnome: The big world of small RNAs
-
P.D. ZamoreB. Haley. Ribo-gnome: the big world of small RNAs. Science. 309:1519-1524 (2005)
-
(2005)
Science
, vol.309
, pp. 1519-1524
-
-
Zamore, P.D.1
Haley, B.2
-
22
-
-
0033555703
-
RNAi and double-strand RNA
-
P.A. Sharp. RNAi and double-strand RNA. Genes Dev. 13:139-141 (1999)
-
(1999)
Genes Dev
, vol.13
, pp. 139-141
-
-
Sharp, P.A.1
-
23
-
-
4444378185
-
Gene therapy progress and prospects. Downregulating gene expression: The impact of RNA interference
-
N.J. Caplen. Gene therapy progress and prospects. Downregulating gene expression: the impact of RNA interference. Gene Ther. 11:1241-1248 (2004)
-
(2004)
Gene Ther
, vol.11
, pp. 1241-1248
-
-
Caplen, N.J.1
-
24
-
-
0037089135
-
Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor
-
T. Holen, M. Amarzguioui, M.T. Wiiger, E. Babaie, and H. Prydz. Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor. Nucleic Acids Res. 30:1757-1766 (2002)
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 1757-1766
-
-
Holen, T.1
Amarzguioui, M.2
Wiiger, M.T.3
Babaie, E.4
Prydz, H.5
-
25
-
-
0141537250
-
Enhanced gene silencing by the application of multiple specific small interfering RNAs
-
J. Ji, M. Wernli, T. Klimkait, and P. Erb. Enhanced gene silencing by the application of multiple specific small interfering RNAs. FEBS Lett. 552:247-252 (2003)
-
(2003)
FEBS Lett
, vol.552
, pp. 247-252
-
-
Ji, J.1
Wernli, M.2
Klimkait, T.3
Erb, P.4
-
26
-
-
0012756249
-
RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase
-
O. DonzeD. Picard. RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res. 30:e46 (2002)
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Donze, O.1
Picard, D.2
-
27
-
-
0024819449
-
Synthesis of small RNAs using T7 RNA polymerase
-
J.F. MilliganO.C. Uhlenbeck. Synthesis of small RNAs using T7 RNA polymerase. Methods Enzymol. 180:51-62 (1989)
-
(1989)
Methods Enzymol
, vol.180
, pp. 51-62
-
-
Milligan, J.F.1
Uhlenbeck, O.C.2
-
28
-
-
1542306855
-
Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase
-
D.H. Kim, M. Longo, Y. Han, P. Lundberg, E. Cantin, and J.J. Rossi. Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase. Nat Biotechnol. 22:321-325 (2004)
-
(2004)
Nat Biotechnol
, vol.22
, pp. 321-325
-
-
Kim, D.H.1
Longo, M.2
Han, Y.3
Lundberg, P.4
Cantin, E.5
Rossi, J.J.6
-
29
-
-
26944498261
-
Approaches for chemically synthesized siRNA and vector-mediated RNAi
-
M. Amarzguioui, J.J. Rossi, and D. Kim. Approaches for chemically synthesized siRNA and vector-mediated RNAi. FEBS Lett. 579:5974-5981 (2005)
-
(2005)
FEBS Lett
, vol.579
, pp. 5974-5981
-
-
Amarzguioui, M.1
Rossi, J.J.2
Kim, D.3
-
30
-
-
0037686295
-
Killing the messenger: Short RNAs that silence gene expression
-
D.M. Dykxhoorn, C.D. Novina, and P.A. Sharp. Killing the messenger: short RNAs that silence gene expression. Nat Rev Mol Cell Biol. 4:457-467 (2003)
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 457-467
-
-
Dykxhoorn, D.M.1
Novina, C.D.2
Sharp, P.A.3
-
31
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
D.A. Rubinson, C.P. Dillon, A.V. Kwiatkowski, C. Sievers, L. Yang, J. Kopinja, D.L. Rooney, M. Zhang, M.M. Ihrig, M.T. McManus, F.B. Gertler, M.L. Scott, and L. Van Parijs. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet. 33:401-406 (2003)
-
(2003)
Nat Genet
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
Dillon, C.P.2
Kwiatkowski, A.V.3
Sievers, C.4
Yang, L.5
Kopinja, J.6
Rooney, D.L.7
Zhang, M.8
Ihrig, M.M.9
McManus, M.T.10
Gertler, F.B.11
Scott, M.L.12
Van Parijs, L.13
-
33
-
-
0037841763
-
Transcription start regions in the human genome are favored targets for MLV integration
-
X. Wu, Y. Li, B. Crise, and S.M. Burgess. Transcription start regions in the human genome are favored targets for MLV integration. Science. 300:1749-1751 (2003)
-
(2003)
Science
, vol.300
, pp. 1749-1751
-
-
Wu, X.1
Li, Y.2
Crise, B.3
Burgess, S.M.4
-
34
-
-
33645136607
-
Therapeutic short hairpin RNA expression in the liver: Viral targets and vectors
-
D. GrimmM.A. Kay. Therapeutic short hairpin RNA expression in the liver: viral targets and vectors. Gene Ther. 13:563-575 (2006)
-
(2006)
Gene Ther
, vol.13
, pp. 563-575
-
-
Grimm, D.1
Kay, M.A.2
-
35
-
-
0346024002
-
Therapeutic siRNAs
-
M. Sioud. Therapeutic siRNAs. Trends Pharmacol Sci. 25:22-28 (2004)
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 22-28
-
-
Sioud, M.1
-
36
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
T.R. Brummelkamp, R. Bernards, and R. Agami. A system for stable expression of short interfering RNAs in mammalian cells. Science. 296:550-553 (2002)
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
37
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
P.J. Paddison, A.A. Caudy, E. Bernstein, G.J. Hannon, and D.S. Conklin. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16:948-958 (2002)
-
(2002)
Genes Dev
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
Hannon, G.J.4
Conklin, D.S.5
-
38
-
-
0036251639
-
Effective expression of small interfering RNA in human cells
-
C.P. Paul, P.D. Good, I. Winer, and D.R. Engelke. Effective expression of small interfering RNA in human cells. Nat Biotechnol. 20:505-508 (2002)
-
(2002)
Nat Biotechnol
, vol.20
, pp. 505-508
-
-
Paul, C.P.1
Good, P.D.2
Winer, I.3
Engelke, D.R.4
-
39
-
-
0642303887
-
Inducible shRNA expression for application in a prostate cancer mouse model
-
F. Czauderna, A. Santel, M. Hinz, M. Fechtner, B. Durieux, G. Fisch, F. Leenders, W. Arnold, K. Giese, A. Klippel, and J. Kaufmann. Inducible shRNA expression for application in a prostate cancer mouse model. Nucleic Acids Res. 31:e127 (2003)
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Czauderna, F.1
Santel, A.2
Hinz, M.3
Fechtner, M.4
Durieux, B.5
Fisch, G.6
Leenders, F.7
Arnold, W.8
Giese, K.9
Klippel, A.10
Kaufmann, J.11
-
40
-
-
1242296872
-
Inducible, reversible, and stable RNA interference in mammalian cells
-
S. Gupta, R.A. Schoer, J.E. Egan, G.J. Hannon, and V. Mittal. Inducible, reversible, and stable RNA interference in mammalian cells. Proc Natl Acad Sci U S A. 101:1927-1932 (2004)
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1927-1932
-
-
Gupta, S.1
Schoer, R.A.2
Egan, J.E.3
Hannon, G.J.4
Mittal, V.5
-
41
-
-
0034052609
-
Control of the functional activity of an antisense RNA by a tetracycline-responsive derivative of the human U6 snRNA promoter
-
J. OhkawaK. Taira. Control of the functional activity of an antisense RNA by a tetracycline-responsive derivative of the human U6 snRNA promoter. Hum Gene Ther. 11:577-585 (2000)
-
(2000)
Hum Gene Ther
, vol.11
, pp. 577-585
-
-
Ohkawa, J.1
Taira, K.2
-
42
-
-
0042662862
-
Establishment of conditional vectors for hairpin siRNA knockdowns
-
S. Matsukura, P.A. Jones, and D. Takai. Establishment of conditional vectors for hairpin siRNA knockdowns. Nucleic Acids Res. 31:e77 (2003)
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Matsukura, S.1
Jones, P.A.2
Takai, D.3
-
43
-
-
33749050585
-
Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivo
-
T. Christoph, A. Grunweller, J. Mika, M.K. Schafer, E.J. Wade, E. Weihe, V.A. Erdmann, R. Frank, C. Gillen, and J. Kurreck. Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivo. Biochem Biophys Res Commun. 350:238-243 (2006)
-
(2006)
Biochem Biophys Res Commun
, vol.350
, pp. 238-243
-
-
Christoph, T.1
Grunweller, A.2
Mika, J.3
Schafer, M.K.4
Wade, E.J.5
Weihe, E.6
Erdmann, V.A.7
Frank, R.8
Gillen, C.9
Kurreck, J.10
-
44
-
-
20244378556
-
RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model
-
S.Q. Harper, P.D. Staber, X. He, S.L. Eliason, I.H. Martins, Q. Mao, L. Yang, R.M. Kotin, H.L. Paulson, and B.L. Davidson. RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model. Proc Natl Acad Sci U S A. 102:5820-5825 (2005)
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 5820-5825
-
-
Harper, S.Q.1
Staber, P.D.2
He, X.3
Eliason, S.L.4
Martins, I.H.5
Mao, Q.6
Yang, L.7
Kotin, R.M.8
Paulson, H.L.9
Davidson, B.L.10
-
45
-
-
25144464388
-
Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice
-
E. Rodriguez-Lebron, E.M. Denovan-Wright, K. Nash, A.S. Lewin, and R.J. Mandel. Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice. Mol Ther. 12:618-633 (2005)
-
(2005)
Mol Ther
, vol.12
, pp. 618-633
-
-
Rodriguez-Lebron, E.1
Denovan-Wright, E.M.2
Nash, K.3
Lewin, A.S.4
Mandel, R.J.5
-
46
-
-
33846580633
-
RNA targeted therapeutics for hematologic malignancies
-
A.M. Gewirtz. RNA targeted therapeutics for hematologic malignancies. Blood Cells Mol Dis. 38:117-119 (2007)
-
(2007)
Blood Cells Mol Dis
, vol.38
, pp. 117-119
-
-
Gewirtz, A.M.1
-
47
-
-
33749167739
-
RNA interference in pain research
-
T. RohlJ. Kurreck. RNA interference in pain research. J Neurochem. 99:371-380 (2006)
-
(2006)
J Neurochem
, vol.99
, pp. 371-380
-
-
Rohl, T.1
Kurreck, J.2
-
48
-
-
0347623204
-
Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)
-
S.P. Persengiev, X. Zhu, and M.R. Green. Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs) RNA. 10:12-18 (2004)
-
(2004)
RNA
, vol.10
, pp. 12-18
-
-
Persengiev, S.P.1
Zhu, X.2
Green, M.R.3
-
49
-
-
67249122712
-
Biological barriers to therapy with antisense and siRNA oligonucleotides
-
R. Juliano, J. Bauman, H. Kang, and X. Ming. Biological barriers to therapy with antisense and siRNA oligonucleotides. Mol Pharm. 6:686-695 (2009)
-
(2009)
Mol Pharm
, vol.6
, pp. 686-695
-
-
Juliano, R.1
Bauman, J.2
Kang, H.3
Ming, X.4
-
50
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
D.M. MosserJ.P. Edwards. Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 8:958-969 (2008)
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
51
-
-
51049092308
-
Factors affecting the clearance and biodistribution of polymeric nanoparticles
-
F. Alexis, E. Pridgen, L.K. Molnar, and O.C. Farokhzad. Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol Pharm. 5:505-515 (2008)
-
(2008)
Mol Pharm
, vol.5
, pp. 505-515
-
-
Alexis, F.1
Pridgen, E.2
Molnar, L.K.3
Farokhzad, O.C.4
-
53
-
-
0029056088
-
Cellular and molecular barriers to gene transfer by a cationic lipid
-
J. Zabner, A.J. Fasbender, T. Moninger, K.A. Poellinger, and M.J. Welsh. Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem. 270:18997-19007 (1995)
-
(1995)
J Biol Chem
, vol.270
, pp. 18997-19007
-
-
Zabner, J.1
Fasbender, A.J.2
Moninger, T.3
Poellinger, K.A.4
Welsh, M.J.5
-
54
-
-
77951168054
-
Breaking down the barriers: siRNA delivery and endosome escape
-
M. DominskaD.M. Dykxhoorn. Breaking down the barriers: siRNA delivery and endosome escape. J Cell Sci. 123:1183-1189 (2010)
-
(2010)
J Cell Sci
, vol.123
, pp. 1183-1189
-
-
Dominska, M.1
Dykxhoorn, D.M.2
-
55
-
-
23044506285
-
Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery
-
C.N. Landen, Jr., A. Chavez-Reyes, C. Bucana, R. Schmandt, M.T. Deavers, G. Lopez-Berestein, and A.K. Sood. Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery. Cancer Res. 65:6910-6918 (2005)
-
(2005)
Cancer Res
, vol.65
, pp. 6910-6918
-
-
Landen Jr., C.N.1
Chavez-Reyes, A.2
Bucana, C.3
Schmandt, R.4
Deavers, M.T.5
Lopez-Berestein, G.6
Sood, A.K.7
-
56
-
-
33646185371
-
RNAi-mediated gene silencing in non-human primates
-
T.S. Zimmermann, A.C. Lee, A. Akinc, B. Bramlage, D. Bumcrot, M.N. Fedoruk, J. Harborth, J.A. Heyes, L.B. Jeffs, M. John, A.D. Judge, K. Lam, K. McClintock, L.V. Nechev, L.R. Palmer, T. Racie, I. Rohl, S. Seiffert, S. Shanmugam, V. Sood, J. Soutschek, I. Toudjarska, A.J. Wheat, E. Yaworski, W. Zedalis, V. Koteliansky, M. Manoharan, H.P. Vornlocher, and I. MacLachlan. RNAi-mediated gene silencing in non-human primates. Nature. 441:111-114 (2006)
-
(2006)
Nature
, vol.441
, pp. 111-114
-
-
Zimmermann, T.S.1
Lee, A.C.2
Akinc, A.3
Bramlage, B.4
Bumcrot, D.5
Fedoruk, M.N.6
Harborth, J.7
Heyes, J.A.8
Jeffs, L.B.9
John, M.10
Judge, A.D.11
Lam, K.12
McClintock, K.13
Nechev, L.V.14
Palmer, L.R.15
Racie, T.16
Rohl, I.17
Seiffert, S.18
Shanmugam, S.19
Sood, V.20
Soutschek, J.21
Toudjarska, I.22
Wheat, A.J.23
Yaworski, E.24
Zedalis, W.25
Koteliansky, V.26
Manoharan, M.27
Vornlocher, H.P.28
MacLachlan, I.29
more..
-
57
-
-
15444373116
-
RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
-
B. Urban-Klein, S. Werth, S. Abuharbeid, F. Czubayko, and A. Aigner. RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene Ther. 12:461-466 (2005)
-
(2005)
Gene Ther
, vol.12
, pp. 461-466
-
-
Urban-Klein, B.1
Werth, S.2
Abuharbeid, S.3
Czubayko, F.4
Aigner, A.5
-
58
-
-
33745614074
-
Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing
-
A.L. Jackson, J. Burchard, D. Leake, A. Reynolds, J. Schelter, J. Guo, J.M. Johnson, L. Lim, J. Karpilow, K. Nichols, W. Marshall, A. Khvorova, and P.S. Linsley. Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing. RNA. 12:1197-1205 (2006)
-
(2006)
RNA
, vol.12
, pp. 1197-1205
-
-
Jackson, A.L.1
Burchard, J.2
Leake, D.3
Reynolds, A.4
Schelter, J.5
Guo, J.6
Johnson, J.M.7
Lim, L.8
Karpilow, J.9
Nichols, K.10
Marshall, W.11
Khvorova, A.12
Linsley, P.S.13
-
59
-
-
0041331496
-
siRNA function in RNAi: A chemical modification analysis
-
Y.L. ChiuT.M. Rana. siRNA function in RNAi: a chemical modification analysis. RNA. 9:1034-1048 (2003)
-
(2003)
RNA
, vol.9
, pp. 1034-1048
-
-
Chiu, Y.L.1
Rana, T.M.2
-
60
-
-
1942533474
-
In vivo activity of nuclease-resistant siRNAs
-
J.M. Layzer, A.P. McCaffrey, A.K. Tanner, Z. Huang, M.A. Kay, and B.A. Sullenger. In vivo activity of nuclease-resistant siRNAs. RNA. 10:766-771 (2004)
-
(2004)
RNA
, vol.10
, pp. 766-771
-
-
Layzer, J.M.1
McCaffrey, A.P.2
Tanner, A.K.3
Huang, Z.4
Kay, M.A.5
Sullenger, B.A.6
-
61
-
-
13744250159
-
Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality
-
J. Elmen, H. Thonberg, K. Ljungberg, M. Frieden, M. Westergaard, Y. Xu, B. Wahren, Z. Liang, H. Orum, T. Koch, and C. Wahlestedt. Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality. Nucleic Acids Res. 33:439-447 (2005)
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 439-447
-
-
Elmen, J.1
Thonberg, H.2
Ljungberg, K.3
Frieden, M.4
Westergaard, M.5
Xu, Y.6
Wahren, B.7
Liang, Z.8
Orum, H.9
Koch, T.10
Wahlestedt, C.11
-
62
-
-
20144389695
-
Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7
-
V. Hornung, M. Guenthner-Biller, C. Bourquin, A. Ablasser, M. Schlee, S. Uematsu, A. Noronha, M. Manoharan, S. Akira, A. de Fougerolles, S. Endres, and G. Hartmann. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 11:263-270 (2005)
-
(2005)
Nat Med
, vol.11
, pp. 263-270
-
-
Hornung, V.1
Guenthner-Biller, M.2
Bourquin, C.3
Ablasser, A.4
Schlee, M.5
Uematsu, S.6
Noronha, A.7
Manoharan, M.8
Akira, S.9
De Fougerolles, A.10
Endres, S.11
Hartmann, G.12
-
63
-
-
8844262560
-
RNA interference and chemically modified small interfering RNAs
-
M. Manoharan. RNA interference and chemically modified small interfering RNAs. Curr Opin Chem Biol. 8:570-579 (2004)
-
(2004)
Curr Opin Chem Biol
, vol.8
, pp. 570-579
-
-
Manoharan, M.1
-
64
-
-
12344283777
-
Modulation of gene expression by antisense and antigene oligodeoxynucleotides and small interfering RNA
-
R.I. Mahato, K. Cheng, and R.V. Guntaka. Modulation of gene expression by antisense and antigene oligodeoxynucleotides and small interfering RNA. Expert Opin Drug Deliv. 2:3-28 (2005)
-
(2005)
Expert Opin Drug Deliv
, vol.2
, pp. 3-28
-
-
Mahato, R.I.1
Cheng, K.2
Guntaka, R.V.3
-
65
-
-
11344257391
-
RNA interference using boranophosphate siRNAs: Structure-activity relationships
-
A.H. Hall, J. Wan, E.E. Shaughnessy, B. Ramsay Shaw, and K.A. Alexander. RNA interference using boranophosphate siRNAs: structure-activity relationships. Nucleic Acids Res. 32:5991-6000 (2004)
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 5991-6000
-
-
Hall, A.H.1
Wan, J.2
Shaughnessy, E.E.3
Ramsay Shaw, B.4
Alexander, K.A.5
-
66
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
A. Khvorova, A. Reynolds, and S.D. Jayasena. Functional siRNAs and miRNAs exhibit strand bias. Cell. 115:209-216 (2003)
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
67
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
D.S. Schwarz, G. Hutvagner, T. Du, Z. Xu, N. Aronin, and P.D. Zamore. Asymmetry in the assembly of the RNAi enzyme complex. Cell. 115:199-208 (2003)
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
Hutvagner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
68
-
-
77955817254
-
Effective stabilization and delivery of siRNA: Reversible siRNA-phospholipid conjugate in nanosized mixed polymeric micelles
-
T. Musacchio, O. Vaze, G. D'Souza, and V.P. Torchilin. Effective stabilization and delivery of siRNA: reversible siRNA-phospholipid conjugate in nanosized mixed polymeric micelles. Bioconjug Chem. 21:1530-1536 (2010)
-
(2010)
Bioconjug Chem
, vol.21
, pp. 1530-1536
-
-
Musacchio, T.1
Vaze, O.2
D'Souza, G.3
Torchilin, V.P.4
-
69
-
-
77957907212
-
Synthesis of oligonucleotides carrying amino lipid groups at the 3′-end for RNA interference studies
-
S. Grijalvo, S.M. Ocampo, J.C. Perales, and R. Eritja. Synthesis of oligonucleotides carrying amino lipid groups at the 3′-end for RNA interference studies. J Org Chem. 75:6806-6813 (2010)
-
(2010)
J Org Chem
, vol.75
, pp. 6806-6813
-
-
Grijalvo, S.1
Ocampo, S.M.2
Perales, J.C.3
Eritja, R.4
-
70
-
-
77952675911
-
Lipophilic siRNAs mediate efficient gene silencing in oligodendrocytes with direct CNS delivery
-
Q. Chen, D. Butler, W. Querbes, R.K. Pandey, P. Ge, M.A. Maier, L. Zhang, K.G. Rajeev, L. Nechev, V. Kotelianski, M. Manoharan, and D.W. Sah. Lipophilic siRNAs mediate efficient gene silencing in oligodendrocytes with direct CNS delivery. J Control Release. 144:227-232 (2010)
-
(2010)
J Control Release
, vol.144
, pp. 227-232
-
-
Chen, Q.1
Butler, D.2
Querbes, W.3
Pandey, R.K.4
Ge, P.5
Maier, M.A.6
Zhang, L.7
Rajeev, K.G.8
Nechev, L.9
Kotelianski, V.10
Manoharan, M.11
Sah, D.W.12
-
71
-
-
35148815670
-
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs
-
C. Wolfrum, S. Shi, K.N. Jayaprakash, M. Jayaraman, G. Wang, R.K. Pandey, K.G. Rajeev, T. Nakayama, K. Charrise, E.M. Ndungo, T. Zimmermann, V. Koteliansky, M. Manoharan, and M. Stoffel. Mechanisms and optimization of in vivo delivery of lipophilic siRNAs. Nat Biotechnol. 25:1149-1157 (2007)
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1149-1157
-
-
Wolfrum, C.1
Shi, S.2
Jayaprakash, K.N.3
Jayaraman, M.4
Wang, G.5
Pandey, R.K.6
Rajeev, K.G.7
Nakayama, T.8
Charrise, K.9
Ndungo, E.M.10
Zimmermann, T.11
Koteliansky, V.12
Manoharan, M.13
Stoffel, M.14
-
73
-
-
0033948268
-
Messenger proteins: Homeoproteins, TAT and others
-
A. Prochiantz. Messenger proteins: homeoproteins, TAT and others. Curr Opin Cell Biol. 12:400-406 (2000)
-
(2000)
Curr Opin Cell Biol
, vol.12
, pp. 400-406
-
-
Prochiantz, A.1
-
74
-
-
0037452668
-
Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes
-
V.P. Torchilin, T.S. Levchenko, R. Rammohan, N. Volodina, B. Papahadjopoulos-Sternberg, and G.G. D'Souza. Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome-DNA complexes. Proc Natl Acad Sci U S A. 100:1972-1977 (2003)
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1972-1977
-
-
Torchilin, V.P.1
Levchenko, T.S.2
Rammohan, R.3
Volodina, N.4
Papahadjopoulos-Sternberg, B.5
D'Souza, G.G.6
-
75
-
-
79952201127
-
Intracellular delivery of nanoparticles with CPPs
-
R. SawantV. Torchilin. Intracellular delivery of nanoparticles with CPPs. Methods Mol Biol. 683:431-451 (2011)
-
(2011)
Methods Mol Biol
, vol.683
, pp. 431-451
-
-
Sawant, R.1
Torchilin, V.2
-
77
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
E. Vives, P. Brodin, and B. Lebleu. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem. 272:16010-16017 (1997)
-
(1997)
J Biol Chem
, vol.272
, pp. 16010-16017
-
-
Vives, E.1
Brodin, P.2
Lebleu, B.3
-
78
-
-
4344651353
-
Visualizing a correlation between siRNA localization, cellular uptake, and RNAi in living cells
-
Y.L. Chiu, A. Ali, C.Y. Chu, H. Cao, and T.M. Rana. Visualizing a correlation between siRNA localization, cellular uptake, and RNAi in living cells. Chem Biol. 11:1165-1175 (2004)
-
(2004)
Chem Biol
, vol.11
, pp. 1165-1175
-
-
Chiu, Y.L.1
Ali, A.2
Chu, C.Y.3
Cao, H.4
Rana, T.M.5
-
79
-
-
66149119384
-
TAT peptides mediated small interfering RNA delivery to Huh-7 cells and efficiently inhibited hepatitis C virus RNA replication
-
S. Meng, B. Wei, R. Xu, K. Zhang, L. Wang, R. Zhang, and J. Li. TAT peptides mediated small interfering RNA delivery to Huh-7 cells and efficiently inhibited hepatitis C virus RNA replication. Intervirology. 52:135-140 (2009)
-
(2009)
Intervirology
, vol.52
, pp. 135-140
-
-
Meng, S.1
Wei, B.2
Xu, R.3
Zhang, K.4
Wang, L.5
Zhang, R.6
Li, J.7
-
80
-
-
8544231403
-
Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation
-
T.J. Davidson, S. Harel, V.A. Arboleda, G.F. Prunell, M.L. Shelanski, L.A. Greene, and C.M. Troy. Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation. J Neurosci. 24:10040-10046 (2004)
-
(2004)
J Neurosci
, vol.24
, pp. 10040-10046
-
-
Davidson, T.J.1
Harel, S.2
Arboleda, V.A.3
Prunell, G.F.4
Shelanski, M.L.5
Greene, L.A.6
Troy, C.M.7
-
81
-
-
56749169583
-
LHRH receptor-mediated delivery of siRNA using polyelectrolyte complex micelles self-assembled from siRNA-PEG-LHRH conjugate and PEI
-
S.H. Kim, J.H. Jeong, S.H. Lee, S.W. Kim, and T.G. Park. LHRH receptor-mediated delivery of siRNA using polyelectrolyte complex micelles self-assembled from siRNA-PEG-LHRH conjugate and PEI. Bioconjug Chem. 19:2156-2162 (2008)
-
(2008)
Bioconjug Chem
, vol.19
, pp. 2156-2162
-
-
Kim, S.H.1
Jeong, J.H.2
Lee, S.H.3
Kim, S.W.4
Park, T.G.5
-
82
-
-
21044445774
-
Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotides containing acid-labile linkages
-
M. Oishi, F. Nagatsugi, S. Sasaki, Y. Nagasaki, and K. Kataoka. Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotides containing acid-labile linkages. Chembiochem. 6:718-725 (2005)
-
(2005)
Chembiochem
, vol.6
, pp. 718-725
-
-
Oishi, M.1
Nagatsugi, F.2
Sasaki, S.3
Nagasaki, Y.4
Kataoka, K.5
-
83
-
-
77953287100
-
Gene silencing efficiency of siRNA-PEG conjugates: Effect of PEGylation site and PEG molecular weight
-
S. Jung, S.H. Lee, H. Mok, H.J. Chung, and T.G. Park. Gene silencing efficiency of siRNA-PEG conjugates: effect of PEGylation site and PEG molecular weight. J Control Release. 144:306-313 (2010)
-
(2010)
J Control Release
, vol.144
, pp. 306-313
-
-
Jung, S.1
Lee, S.H.2
Mok, H.3
Chung, H.J.4
Park, T.G.5
-
84
-
-
84857429719
-
Di- and Triblock siRNA-PEG Copolymers: PEG Density Effect of Polyelectrolyte Complexes on Cellular Uptake and Gene Silencing Efficiency
-
S.H. Lee, H. Mok, and T.G. Park. Di- and Triblock siRNA-PEG Copolymers: PEG Density Effect of Polyelectrolyte Complexes on Cellular Uptake and Gene Silencing Efficiency. Macromol Biosci (2010)
-
(2010)
Macromol Biosci
-
-
Lee, S.H.1
Mok, H.2
Park, T.G.3
-
85
-
-
76849103897
-
Multifunctional siRNA delivery system: Polyelectrolyte complex micelles of six-arm PEG conjugate of siRNA and cell penetrating peptide with crosslinked fusogenic peptide
-
S.W. Choi, S.H. Lee, H. Mok, and T.G. Park. Multifunctional siRNA delivery system: polyelectrolyte complex micelles of six-arm PEG conjugate of siRNA and cell penetrating peptide with crosslinked fusogenic peptide. Biotechnol Prog. 26:57-63 (2010)
-
(2010)
Biotechnol Prog
, vol.26
, pp. 57-63
-
-
Choi, S.W.1
Lee, S.H.2
Mok, H.3
Park, T.G.4
-
86
-
-
34247153120
-
Intracellular siRNA delivery system using polyelectrolyte complex micelles prepared from VEGF siRNA-PEG conjugate and cationic fusogenic peptide
-
S.H. Lee, S.H. Kim, and T.G. Park. Intracellular siRNA delivery system using polyelectrolyte complex micelles prepared from VEGF siRNA-PEG conjugate and cationic fusogenic peptide. Biochem Biophys Res Commun. 357:511-516 (2007)
-
(2007)
Biochem Biophys Res Commun
, vol.357
, pp. 511-516
-
-
Lee, S.H.1
Kim, S.H.2
Park, T.G.3
-
87
-
-
78649260473
-
Targeted delivery of siRNA to hepatocytes and hepatic stellate cells by bioconjugation
-
L. ZhuR.I. Mahato. Targeted delivery of siRNA to hepatocytes and hepatic stellate cells by bioconjugation. Bioconjug Chem. 21:2119-2127 (2010)
-
(2010)
Bioconjug Chem
, vol.21
, pp. 2119-2127
-
-
Zhu, L.1
Mahato, R.I.2
-
88
-
-
13644254495
-
Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells
-
M. Oishi, Y. Nagasaki, K. Itaka, N. Nishiyama, and K. Kataoka. Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells. J Am Chem Soc. 127:1624-1625 (2005)
-
(2005)
J Am Chem Soc
, vol.127
, pp. 1624-1625
-
-
Oishi, M.1
Nagasaki, Y.2
Itaka, K.3
Nishiyama, N.4
Kataoka, K.5
-
89
-
-
77049109902
-
Intracellular trafficking and unpacking of siRNA/quantum dot-PEI complexes modified with and without cell penetrating peptide: Confocal and flow cytometric FRET analysis
-
H. Lee, I.K. Kim, and T.G. Park. Intracellular trafficking and unpacking of siRNA/quantum dot-PEI complexes modified with and without cell penetrating peptide: confocal and flow cytometric FRET analysis. Bioconjug Chem. 21:289-295 (2010)
-
(2010)
Bioconjug Chem
, vol.21
, pp. 289-295
-
-
Lee, H.1
Kim, I.K.2
Park, T.G.3
-
90
-
-
78349306448
-
Surface functionalized hollow manganese oxide nanoparticles for cancer targeted siRNA delivery and magnetic resonance imaging
-
K.H. Bae, K. Lee, C. Kim, and T.G. Park. Surface functionalized hollow manganese oxide nanoparticles for cancer targeted siRNA delivery and magnetic resonance imaging. Biomaterials. 32:176-184 (2011)
-
(2011)
Biomaterials
, vol.32
, pp. 176-184
-
-
Bae, K.H.1
Lee, K.2
Kim, C.3
Park, T.G.4
-
91
-
-
62149147508
-
Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma
-
L. Zhuang, R.A. Scolyer, C.S. Lee, S.W. McCarthy, W.A. Cooper, X.D. Zhang, J.F. Thompson, and P. Hersey. Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma. Histopathology. 54:462-470 (2009)
-
(2009)
Histopathology
, vol.54
, pp. 462-470
-
-
Zhuang, L.1
Scolyer, R.A.2
Lee, C.S.3
McCarthy, S.W.4
Cooper, W.A.5
Zhang, X.D.6
Thompson, J.F.7
Hersey, P.8
-
92
-
-
78650883368
-
Multifunctional nanomedicine platform for cancer specific delivery of siRNA by superparamagnetic iron oxide nanoparticles-dendrimer complexes
-
O. Taratula, O. Garbuzenko, R. Savla, Y.A. Wang, H. He, and T. Minko. Multifunctional nanomedicine platform for cancer specific delivery of siRNA by superparamagnetic iron oxide nanoparticles-dendrimer complexes. Curr Drug Deliv. 8:59-69 (2011)
-
(2011)
Curr Drug Deliv
, vol.8
, pp. 59-69
-
-
Taratula, O.1
Garbuzenko, O.2
Savla, R.3
Wang, Y.A.4
He, H.5
Minko, T.6
-
93
-
-
66149171496
-
Peptide-functionalized nanogels for targeted siRNA delivery
-
W.H. Blackburn, E.B. Dickerson, M.H. Smith, J.F. McDonald, and L.A. Lyon. Peptide-functionalized nanogels for targeted siRNA delivery. Bioconjug Chem. 20:960-968 (2009)
-
(2009)
Bioconjug Chem
, vol.20
, pp. 960-968
-
-
Blackburn, W.H.1
Dickerson, E.B.2
Smith, M.H.3
McDonald, J.F.4
Lyon, L.A.5
-
94
-
-
77951699994
-
Sustained small interfering RNA delivery by mesoporous silicon particles
-
T. Tanaka, L.S. Mangala, P.E. Vivas-Mejia, R. Nieves-Alicea, A.P. Mann, E. Mora, H.D. Han, M.M. Shahzad, X. Liu, R. Bhavane, J. Gu, J.R. Fakhoury, C. Chiappini, C. Lu, K. Matsuo, B. Godin, R.L. Stone, A.M. Nick, G. Lopez-Berestein, A.K. Sood, and M. Ferrari. Sustained small interfering RNA delivery by mesoporous silicon particles. Cancer Res. 70:3687-3696 (2010)
-
(2010)
Cancer Res
, vol.70
, pp. 3687-3696
-
-
Tanaka, T.1
Mangala, L.S.2
Vivas-Mejia, P.E.3
Nieves-Alicea, R.4
Mann, A.P.5
Mora, E.6
Han, H.D.7
Shahzad, M.M.8
Liu, X.9
Bhavane, R.10
Gu, J.11
Fakhoury, J.R.12
Chiappini, C.13
Lu, C.14
Matsuo, K.15
Godin, B.16
Stone, R.L.17
Nick, A.M.18
Lopez-Berestein, G.19
Sood, A.K.20
Ferrari, M.21
more..
-
95
-
-
33646144003
-
siRNA-containing liposomes modified with polyarginine effectively silence the targeted gene
-
C. Zhang, N. Tang, X. Liu, W. Liang, W. Xu, and V.P. Torchilin. siRNA-containing liposomes modified with polyarginine effectively silence the targeted gene. J Control Release. 112:229-239 (2006)
-
(2006)
J Control Release
, vol.112
, pp. 229-239
-
-
Zhang, C.1
Tang, N.2
Liu, X.3
Liang, W.4
Xu, W.5
Torchilin, V.P.6
-
96
-
-
77950571073
-
pH-responsive polymeric sirna carriers sensitize multidrug resistant ovarian cancer cells to doxorubicin via knockdown of polo-like kinase 1
-
D.S. Benoit, S.M. Henry, A.D. Shubin, A.S. Hoffman, and P.S. Stayton. pH-responsive polymeric sirna carriers sensitize multidrug resistant ovarian cancer cells to doxorubicin via knockdown of polo-like kinase 1. Mol Pharm. 7:442-455 (2010)
-
(2010)
Mol Pharm
, vol.7
, pp. 442-455
-
-
Benoit, D.S.1
Henry, S.M.2
Shubin, A.D.3
Hoffman, A.S.4
Stayton, P.S.5
-
97
-
-
70349129495
-
Dendrimers: Emerging polymers for drug-delivery systems
-
B.K. Nanjwade, H.M. Bechra, G.K. Derkar, F.V. Manvi, and V.K. Nanjwade. Dendrimers: emerging polymers for drug-delivery systems. Eur J Pharm Sci. 38:185-196 (2009)
-
(2009)
Eur J Pharm Sci
, vol.38
, pp. 185-196
-
-
Nanjwade, B.K.1
Bechra, H.M.2
Derkar, G.K.3
Manvi, F.V.4
Nanjwade, V.K.5
-
98
-
-
35649024193
-
Importance of size-to-charge ratio in construction of stable and uniform nanoscale RNA/dendrimer complexes
-
X.C. Shen, J. Zhou, X. Liu, J. Wu, F. Qu, Z.L. Zhang, D.W. Pang, G. Quelever, C.C. Zhang, and L. Peng. Importance of size-to-charge ratio in construction of stable and uniform nanoscale RNA/dendrimer complexes. Org Biomol Chem. 5:3674-3681 (2007)
-
(2007)
Org Biomol Chem
, vol.5
, pp. 3674-3681
-
-
Shen, X.C.1
Zhou, J.2
Liu, X.3
Wu, J.4
Qu, F.5
Zhang, Z.L.6
Pang, D.W.7
Quelever, G.8
Zhang, C.C.9
Peng, L.10
-
99
-
-
77956633797
-
In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers
-
P. Ofek, W. Fischer, M. Calderon, R. Haag, and R. Satchi-Fainaro. In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers. FASEB J. 24:3122-3134 (2010)
-
(2010)
FASEB J
, vol.24
, pp. 3122-3134
-
-
Ofek, P.1
Fischer, W.2
Calderon, M.3
Haag, R.4
Satchi-Fainaro, R.5
-
100
-
-
64149113037
-
Internally cationic polyamidoamine PAMAM-OH dendrimers for siRNA delivery: Effect of the degree of quaternization and cancer targeting
-
M.L. Patil, M. Zhang, O. Taratula, O.B. Garbuzenko, H. He, and T. Minko. Internally cationic polyamidoamine PAMAM-OH dendrimers for siRNA delivery: effect of the degree of quaternization and cancer targeting. Biomacromolecules. 10:258-266 (2009)
-
(2009)
Biomacromolecules
, vol.10
, pp. 258-266
-
-
Patil, M.L.1
Zhang, M.2
Taratula, O.3
Garbuzenko, O.B.4
He, H.5
Minko, T.6
-
101
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
-
O. Boussif, F. Lezoualc'h, M.A. Zanta, M.D. Mergny, D. Scherman, B. Demeneix, and J.P. Behr. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci U S A. 92:7297-7301 (1995)
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7297-7301
-
-
Boussif, O.1
Lezoualc'h, F.2
Zanta, M.A.3
Mergny, M.D.4
Scherman, D.5
Demeneix, B.6
Behr, J.P.7
-
102
-
-
0242414440
-
Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes
-
N.D. Sonawane, F.C. Szoka, Jr., and A.S. Verkman. Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem. 278:44826-44831 (2003)
-
(2003)
J Biol Chem
, vol.278
, pp. 44826-44831
-
-
Sonawane, N.D.1
Szoka Jr., F.C.2
Verkman, A.S.3
-
103
-
-
70349551739
-
Functional delivery of siRNA in mice using dendriworms
-
A. Agrawal, D.H. Min, N. Singh, H. Zhu, A. Birjiniuk, G. von Maltzahn, T.J. Harris, D. Xing, S.D. Woolfenden, P.A. Sharp, A. Charest, and S. Bhatia. Functional delivery of siRNA in mice using dendriworms. ACS Nano. 3:2495-2504 (2009)
-
(2009)
ACS Nano
, vol.3
, pp. 2495-2504
-
-
Agrawal, A.1
Min, D.H.2
Singh, N.3
Zhu, H.4
Birjiniuk, A.5
Von Maltzahn, G.6
Harris, T.J.7
Xing, D.8
Woolfenden, S.D.9
Sharp, P.A.10
Charest, A.11
Bhatia, S.12
-
104
-
-
24744437125
-
Functionalization of carbon nanotubes via cleavable disulfide bonds for efficient intracellular delivery of siRNA and potent gene silencing
-
N.W. Kam, Z. Liu, and H. Dai. Functionalization of carbon nanotubes via cleavable disulfide bonds for efficient intracellular delivery of siRNA and potent gene silencing. J Am Chem Soc. 127:12492-12493 (2005)
-
(2005)
J Am Chem Soc
, vol.127
, pp. 12492-12493
-
-
Kam, N.W.1
Liu, Z.2
Dai, H.3
-
105
-
-
34247582332
-
siRNA delivery into human T cells and primary cells with carbon-nanotube transporters
-
Z. Liu, M. Winters, M. Holodniy, and H. Dai. siRNA delivery into human T cells and primary cells with carbon-nanotube transporters. Angew Chem Int Ed Engl. 46:2023-2027 (2007)
-
(2007)
Angew Chem Int Ed Engl
, vol.46
, pp. 2023-2027
-
-
Liu, Z.1
Winters, M.2
Holodniy, M.3
Dai, H.4
-
106
-
-
78649889077
-
Enhanced cellular internalization and gene silencing with a series of cationic dendron-multiwalled carbon nanotube:SiRNA complexes
-
K.T. Al-Jamal, F.M. Toma, A. Yilmazer, H. Ali-Boucetta, A. Nunes, M.A. Herrero, B. Tian, A. Eddaoui, W.T. Al-Jamal, A. Bianco, M. Prato, and K. Kostarelo. Enhanced cellular internalization and gene silencing with a series of cationic dendron-multiwalled carbon nanotube:siRNA complexes. FASEB J. 24:4354-4365 (2010)
-
(2010)
FASEB J
, vol.24
, pp. 4354-4365
-
-
Al-Jamal, K.T.1
Toma, F.M.2
Yilmazer, A.3
Ali-Boucetta, H.4
Nunes, A.5
Herrero, M.A.6
Tian, B.7
Eddaoui, A.8
Al-Jamal, W.T.9
Bianco, A.10
Prato, M.11
Kostarelo, K.12
-
107
-
-
76749164888
-
Chemosensitization of cancer cells by siRNA using targeted nanogel delivery
-
E.B. Dickerson, W.H. Blackburn, M.H. Smith, L.B. Kapa, L.A. Lyon, and J.F. McDonald. Chemosensitization of cancer cells by siRNA using targeted nanogel delivery. BMC Cancer. 10:10 (2010)
-
(2010)
BMC Cancer
, vol.10
, pp. 10
-
-
Dickerson, E.B.1
Blackburn, W.H.2
Smith, M.H.3
Kapa, L.B.4
Lyon, L.A.5
McDonald, J.F.6
-
108
-
-
77956271401
-
Efficient siRNA delivery based on PEGylated and partially quaternized polyamine nanogels: Enhanced gene silencing activity by the cooperative effect of tertiary and quaternary amino groups in the core
-
A. Tamura, M. Oishi, and Y. Nagasaki. Efficient siRNA delivery based on PEGylated and partially quaternized polyamine nanogels: enhanced gene silencing activity by the cooperative effect of tertiary and quaternary amino groups in the core. J Control Release. 146:378-387 (2010)
-
(2010)
J Control Release
, vol.146
, pp. 378-387
-
-
Tamura, A.1
Oishi, M.2
Nagasaki, Y.3
-
109
-
-
34248544999
-
Target-specific intracellular delivery of siRNA using degradable hyaluronic acid nanogels
-
H. Lee, H. Mok, S. Lee, Y.K. Oh, and T.G. Park. Target-specific intracellular delivery of siRNA using degradable hyaluronic acid nanogels. J Control Release. 119:245-252 (2007)
-
(2007)
J Control Release
, vol.119
, pp. 245-252
-
-
Lee, H.1
Mok, H.2
Lee, S.3
Oh, Y.K.4
Park, T.G.5
-
110
-
-
42549146715
-
Size Controlled Synthesis of Monodispersed, Core/Shell Nanogels
-
W.H. BlackburnL.A. Lyon. Size Controlled Synthesis of Monodispersed, Core/Shell Nanogels. Colloid Polym Sci. 286:563-569 (2008)
-
(2008)
Colloid Polym Sci
, vol.286
, pp. 563-569
-
-
Blackburn, W.H.1
Lyon, L.A.2
-
111
-
-
33746293279
-
Mechanics versus thermodynamics: Swelling in multiple-temperature- sensitive core-shell microgels
-
I. Berndt, C. Popescu, F.J. Wortmann, and W. Richtering. Mechanics versus thermodynamics: swelling in multiple-temperature-sensitive core-shell microgels. Angew Chem Int Ed Engl. 45:1081-1085 (2006)
-
(2006)
Angew Chem Int Ed Engl
, vol.45
, pp. 1081-1085
-
-
Berndt, I.1
Popescu, C.2
Wortmann, F.J.3
Richtering, W.4
-
112
-
-
77954314924
-
Prolonged gene silencing by combining siRNA nanogels and photochemical internalization
-
K. Raemdonck, B. Naeye, A. Hogset, J. Demeester, and S.C. De Smedt. Prolonged gene silencing by combining siRNA nanogels and photochemical internalization. J Control Release. 145:281-288 (2010)
-
(2010)
J Control Release
, vol.145
, pp. 281-288
-
-
Raemdonck, K.1
Naeye, B.2
Hogset, A.3
Demeester, J.4
De Smedt, S.C.5
-
113
-
-
49749086064
-
Dynamics of photoinduced endosomal release of polyplexes
-
K.G. de Bruin, C. Fella, M. Ogris, E. Wagner, N. Ruthardt, and C. Brauchle. Dynamics of photoinduced endosomal release of polyplexes. J Control Release. 130:175-182 (2008)
-
(2008)
J Control Release
, vol.130
, pp. 175-182
-
-
De Bruin, K.G.1
Fella, C.2
Ogris, M.3
Wagner, E.4
Ruthardt, N.5
Brauchle, C.6
-
114
-
-
37249003262
-
Photochemical internalization: A new tool for drug delivery
-
K. Berg, M. Folini, L. Prasmickaite, P.K. Selbo, A. Bonsted, B.O. Engesaeter, N. Zaffaroni, A. Weyergang, A. Dietze, G.M. Maelandsmo, E. Wagner, O.J. Norum, and A. Hogset. Photochemical internalization: a new tool for drug delivery. Curr Pharm Biotechnol. 8:362-372 (2007)
-
(2007)
Curr Pharm Biotechnol
, vol.8
, pp. 362-372
-
-
Berg, K.1
Folini, M.2
Prasmickaite, L.3
Selbo, P.K.4
Bonsted, A.5
Engesaeter, B.O.6
Zaffaroni, N.7
Weyergang, A.8
Dietze, A.9
Maelandsmo, G.M.10
Wagner, E.11
Norum, O.J.12
Hogset, A.13
-
115
-
-
63849265378
-
A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation
-
X. Zheng, C. Vladau, X. Zhang, M. Suzuki, T.E. Ichim, Z.X. Zhang, M. Li, E. Carrier, B. Garcia, A.M. Jevnikar, and W.P. Min. A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation. Blood. 113:2646-2654 (2009)
-
(2009)
Blood
, vol.113
, pp. 2646-2654
-
-
Zheng, X.1
Vladau, C.2
Zhang, X.3
Suzuki, M.4
Ichim, T.E.5
Zhang, Z.X.6
Li, M.7
Carrier, E.8
Garcia, B.9
Jevnikar, A.M.10
Min, W.P.11
-
116
-
-
0036784335
-
Translocation of liposomes into cancer cells by cell-penetrating peptides penetratin and tat: A kinetic and efficacy study
-
Y.L. Tseng, J.J. Liu, and R.L. Hong. Translocation of liposomes into cancer cells by cell-penetrating peptides penetratin and tat: a kinetic and efficacy study. Mol Pharmacol. 62:864-872 (2002)
-
(2002)
Mol Pharmacol
, vol.62
, pp. 864-872
-
-
Tseng, Y.L.1
Liu, J.J.2
Hong, R.L.3
-
117
-
-
40449083756
-
Targeted delivery of small interfering RNA: Approaching effective cancer therapies
-
K.F. PirolloE.H. Chang. Targeted delivery of small interfering RNA: approaching effective cancer therapies. Cancer Res. 68:1247-1250 (2008)
-
(2008)
Cancer Res
, vol.68
, pp. 1247-1250
-
-
Pirollo, K.F.1
Chang, E.H.2
-
118
-
-
33645573205
-
Cell penetrating peptides enhance intracellular translocation and function of siRNA encapsulated in Pegylated liposomes
-
W. Wang, N. Tang, C.L. Zhang, X.J. Liu, H. Hu, Z.X. Zhang, and W. Liang. [Cell penetrating peptides enhance intracellular translocation and function of siRNA encapsulated in Pegylated liposomes]. Yao Xue Xue Bao. 41:142-148 (2006)
-
(2006)
Yao Xue Xue Bao
, vol.41
, pp. 142-148
-
-
Wang, W.1
Tang, N.2
Zhang, C.L.3
Liu, X.J.4
Hu, H.5
Zhang, Z.X.6
Liang, W.7
-
119
-
-
33750552967
-
Targeting liposomal chemotherapy via both tumor cell-specific and tumor vasculature-specific ligands potentiates therapeutic efficacy
-
F. Pastorino, C. Brignole, D. Di Paolo, B. Nico, A. Pezzolo, D. Marimpietri, G. Pagnan, F. Piccardi, M. Cilli, R. Longhi, D. Ribatti, A. Corti, T.M. Allen, and M. Ponzoni. Targeting liposomal chemotherapy via both tumor cell-specific and tumor vasculature-specific ligands potentiates therapeutic efficacy. Cancer Res. 66:10073-10082 (2006)
-
(2006)
Cancer Res
, vol.66
, pp. 10073-10082
-
-
Pastorino, F.1
Brignole, C.2
Di Paolo, D.3
Nico, B.4
Pezzolo, A.5
Marimpietri, D.6
Pagnan, G.7
Piccardi, F.8
Cilli, M.9
Longhi, R.10
Ribatti, D.11
Corti, A.12
Allen, T.M.13
Ponzoni, M.14
-
120
-
-
52049117189
-
Evolution of phage display: From bioactive peptides to bioselective nanomaterials
-
V. Petrenko. Evolution of phage display: from bioactive peptides to bioselective nanomaterials. Expert Opin Drug Deliv. 5:825-836 (2008)
-
(2008)
Expert Opin Drug Deliv
, vol.5
, pp. 825-836
-
-
Petrenko, V.1
-
121
-
-
84857434460
-
Delivery of siRNA into breast cancer cells via phage fusion protein-targeted liposomes
-
D. Bedi, T. Musacchio, O.A. Fagbohun, J.W. Gillespie, P. Deinnocentes, R.C. Bird, L. Bookbinder, V.P. Torchilin, and V.A. Petrenko. Delivery of siRNA into breast cancer cells via phage fusion protein-targeted liposomes. Nanomedicine (2010)
-
(2010)
Nanomedicine
-
-
Bedi, D.1
Musacchio, T.2
Fagbohun, O.A.3
Gillespie, J.W.4
Deinnocentes, P.5
Bird, R.C.6
Bookbinder, L.7
Torchilin, V.P.8
Petrenko, V.A.9
-
122
-
-
77349098528
-
Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo
-
A.L. Cardoso, P. Costa, L.P. de Almeida, S. Simoes, N. Plesnila, C. Culmsee, E. Wagner, and M.C. de Lima. Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo. J Control Release. 142:392-403 (2010)
-
(2010)
J Control Release
, vol.142
, pp. 392-403
-
-
Cardoso, A.L.1
Costa, P.2
De Almeida, L.P.3
Simoes, S.4
Plesnila, N.5
Culmsee, C.6
Wagner, E.7
De Lima, M.C.8
-
123
-
-
82055164757
-
Controlled synthesis of PEI-coated gold nanoparticles using reductive catechol chemistry for siRNA delivery
-
Y. Lee, S.H. Lee, J.S. Kim, A. Maruyama, X. Chen, and T.G. Park. Controlled synthesis of PEI-coated gold nanoparticles using reductive catechol chemistry for siRNA delivery. J Control Release (2010)
-
(2010)
J Control Release
-
-
Lee, Y.1
Lee, S.H.2
Kim, J.S.3
Maruyama, A.4
Chen, X.5
Park, T.G.6
-
124
-
-
67349234877
-
Penetration and efficacy of VEGF siRNA using polyelectrolyte complex micelles in a human solid tumor model in-vitro
-
A.M. Al-Abd, S.H. Lee, S.H. Kim, J.H. Cha, T.G. Park, S.J. Lee, and H.J. Kuh. Penetration and efficacy of VEGF siRNA using polyelectrolyte complex micelles in a human solid tumor model in-vitro. J Control Release. 137:130-135 (2009)
-
(2009)
J Control Release
, vol.137
, pp. 130-135
-
-
Al-Abd, A.M.1
Lee, S.H.2
Kim, S.H.3
Cha, J.H.4
Park, T.G.5
Lee, S.J.6
Kuh, H.J.7
-
125
-
-
74849097084
-
Co-delivery of siRNA and paclitaxel into cancer cells by biodegradable cationic micelles based on PDMAEMA-PCL-PDMAEMA triblock copolymers
-
C. Zhu, S. Jung, S. Luo, F. Meng, X. Zhu, T.G. Park, and Z. Zhong. Co-delivery of siRNA and paclitaxel into cancer cells by biodegradable cationic micelles based on PDMAEMA-PCL-PDMAEMA triblock copolymers. Biomaterials. 31:2408-2416 (2010)
-
(2010)
Biomaterials
, vol.31
, pp. 2408-2416
-
-
Zhu, C.1
Jung, S.2
Luo, S.3
Meng, F.4
Zhu, X.5
Park, T.G.6
Zhong, Z.7
-
126
-
-
58549112795
-
Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery
-
S. Matsumoto, R.J. Christie, N. Nishiyama, K. Miyata, A. Ishii, M. Oba, H. Koyama, Y. Yamasaki, and K. Kataoka. Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery. Biomacromolecules. 10:119-127 (2009)
-
(2009)
Biomacromolecules
, vol.10
, pp. 119-127
-
-
Matsumoto, S.1
Christie, R.J.2
Nishiyama, N.3
Miyata, K.4
Ishii, A.5
Oba, M.6
Koyama, H.7
Yamasaki, Y.8
Kataoka, K.9
-
128
-
-
0036164530
-
Vehicles for oligonucleotide delivery to tumours
-
C.R. Dass. Vehicles for oligonucleotide delivery to tumours. J Pharm Pharmacol. 54:3-27 (2002)
-
(2002)
J Pharm Pharmacol
, vol.54
, pp. 3-27
-
-
Dass, C.R.1
-
129
-
-
0035793047
-
Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse
-
C.J. Mann, K. Honeyman, A.J. Cheng, T. Ly, F. Lloyd, S. Fletcher, J.E. Morgan, T.A. Partridge, and S.D. Wilton. Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse. Proc Natl Acad Sci U S A. 98:42-47 (2001)
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 42-47
-
-
Mann, C.J.1
Honeyman, K.2
Cheng, A.J.3
Ly, T.4
Lloyd, F.5
Fletcher, S.6
Morgan, J.E.7
Partridge, T.A.8
Wilton, S.D.9
-
130
-
-
60649114699
-
Polymersome delivery of siRNA and antisense oligonucleotides
-
Y. Kim, M. Tewari, J.D. Pajerowski, S. Cai, S. Sen, J.H. Williams, S.R. Sirsi, G.J. Lutz, and D.E. Discher. Polymersome delivery of siRNA and antisense oligonucleotides. J Control Release. 134:132-140 (2009)
-
(2009)
J Control Release
, vol.134
, pp. 132-140
-
-
Kim, Y.1
Tewari, M.2
Pajerowski, J.D.3
Cai, S.4
Sen, S.5
Williams, J.H.6
Sirsi, S.R.7
Lutz, G.J.8
Discher, D.E.9
-
131
-
-
33745770615
-
Shrinkage of a rapidly growing tumor by drug-loaded polymersomes: pH-triggered release through copolymer degradation
-
F. Ahmed, R.I. Pakunlu, G. Srinivas, A. Brannan, F. Bates, M.L. Klein, T. Minko, and D.E. Discher. Shrinkage of a rapidly growing tumor by drug-loaded polymersomes: pH-triggered release through copolymer degradation. Mol Pharm. 3:340-350 (2006)
-
(2006)
Mol Pharm
, vol.3
, pp. 340-350
-
-
Ahmed, F.1
Pakunlu, R.I.2
Srinivas, G.3
Brannan, A.4
Bates, F.5
Klein, M.L.6
Minko, T.7
Discher, D.E.8
-
132
-
-
34848839868
-
Micelles of different morphologies - Advantages of worm-like filomicelles of PEO-PCL in paclitaxel delivery
-
S. Cai, K. Vijayan, D. Cheng, E.M. Lima, and D.E. Discher. Micelles of different morphologies - advantages of worm-like filomicelles of PEO-PCL in paclitaxel delivery. Pharm Res. 24:2099-2109 (2007)
-
(2007)
Pharm Res
, vol.24
, pp. 2099-2109
-
-
Cai, S.1
Vijayan, K.2
Cheng, D.3
Lima, E.M.4
Discher, D.E.5
-
133
-
-
78650798166
-
Cationic nano-copolymers mediated IKKbeta targeting siRNA to modulate wound healing in a monkey model of glaucoma filtration surgery
-
H. Ye, Y. Qian, M. Lin, Y. Duan, X. Sun, Y. Zhuo, and J. Ge. Cationic nano-copolymers mediated IKKbeta targeting siRNA to modulate wound healing in a monkey model of glaucoma filtration surgery. Mol Vis. 16:2502-2510 (2010)
-
(2010)
Mol Vis
, vol.16
, pp. 2502-2510
-
-
Ye, H.1
Qian, Y.2
Lin, M.3
Duan, Y.4
Sun, X.5
Zhuo, Y.6
Ge, J.7
-
134
-
-
77955842890
-
Inhibition of experimental choroidal neovascularization in mice by anti-VEGFA/VEGFR2 or non-specific siRNA
-
L. Gu, H. Chen, J. Tuo, X. Gao, and L. Chen. Inhibition of experimental choroidal neovascularization in mice by anti-VEGFA/VEGFR2 or non-specific siRNA. Exp Eye Res. 91:433-439 (2010)
-
(2010)
Exp Eye Res
, vol.91
, pp. 433-439
-
-
Gu, L.1
Chen, H.2
Tuo, J.3
Gao, X.4
Chen, L.5
-
135
-
-
77956205950
-
Liposome-siRNA-peptide complexes cross the blood-brain barrier and significantly decrease PrP on neuronal cells and PrP in infected cell cultures
-
B. Pulford, N. Reim, A. Bell, J. Veatch, G. Forster, H. Bender, C. Meyerett, S. Hafeman, B. Michel, T. Johnson, A.C. Wyckoff, G. Miele, C. Julius, J. Kranich, A. Schenkel, S. Dow, and M.D. Zabel. Liposome-siRNA-peptide complexes cross the blood-brain barrier and significantly decrease PrP on neuronal cells and PrP in infected cell cultures. PLoS One. 5:e11085 (2010)
-
(2010)
PLoS One
, vol.5
-
-
Pulford, B.1
Reim, N.2
Bell, A.3
Veatch, J.4
Forster, G.5
Bender, H.6
Meyerett, C.7
Hafeman, S.8
Michel, B.9
Johnson, T.10
Wyckoff, A.C.11
Miele, G.12
Julius, C.13
Kranich, J.14
Schenkel, A.15
Dow, S.16
Zabel, M.D.17
-
136
-
-
77349107167
-
Neuroprotection by biodegradable PAMAM ester (e-PAM-R)-mediated HMGB1 siRNA delivery in primary cortical cultures and in the postischemic brain
-
I.D. Kim, C.M. Lim, J.B. Kim, H.Y. Nam, K. Nam, S.W. Kim, J.S. Park, and J.K. Lee. Neuroprotection by biodegradable PAMAM ester (e-PAM-R)-mediated HMGB1 siRNA delivery in primary cortical cultures and in the postischemic brain. J Control Release. 142:422-430 (2010)
-
(2010)
J Control Release
, vol.142
, pp. 422-430
-
-
Kim, I.D.1
Lim, C.M.2
Kim, J.B.3
Nam, H.Y.4
Nam, K.5
Kim, S.W.6
Park, J.S.7
Lee, J.K.8
-
137
-
-
78651341419
-
Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles
-
E.J. Nielsen, J.M. Nielsen, D. Becker, A. Karlas, H. Prakash, S.Z. Glud, J. Merrison, F. Besenbacher, T.F. Meyer, J. Kjems, and K.A. Howard. Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles. Pharm Res. 27:2520-2527 (2010)
-
(2010)
Pharm Res
, vol.27
, pp. 2520-2527
-
-
Nielsen, E.J.1
Nielsen, J.M.2
Becker, D.3
Karlas, A.4
Prakash, H.5
Glud, S.Z.6
Merrison, J.7
Besenbacher, F.8
Meyer, T.F.9
Kjems, J.10
Howard, K.A.11
-
138
-
-
77954120438
-
Efficient gene silencing in lungs and liver using imidazole-modified chitosan as a nanocarrier for small interfering RNA
-
B. Ghosn, A. Singh, M. Li, A.V. Vlassov, C. Burnett, N. Puri, and K. Roy. Efficient gene silencing in lungs and liver using imidazole-modified chitosan as a nanocarrier for small interfering RNA. Oligonucleotides. 20:163-172 (2010)
-
(2010)
Oligonucleotides
, vol.20
, pp. 163-172
-
-
Ghosn, B.1
Singh, A.2
Li, M.3
Vlassov, A.V.4
Burnett, C.5
Puri, N.6
Roy, K.7
-
139
-
-
77957264207
-
Delivery of small interfering RNA with a synthetic collagen poly(Pro-Hyp-Gly) for gene silencing in vitro and in vivo
-
T. Adachi, E. Kawakami, N. Ishimaru, T. Ochiya, Y. Hayashi, H. Ohuchi, M. Tanihara, E. Tanaka, and S. Noji. Delivery of small interfering RNA with a synthetic collagen poly(Pro-Hyp-Gly) for gene silencing in vitro and in vivo. Dev Growth Differ. 52:693-699 (2010)
-
(2010)
Dev Growth Differ
, vol.52
, pp. 693-699
-
-
Adachi, T.1
Kawakami, E.2
Ishimaru, N.3
Ochiya, T.4
Hayashi, Y.5
Ohuchi, H.6
Tanihara, M.7
Tanaka, E.8
Noji, S.9
-
140
-
-
44649114578
-
Optical in vivo imaging of electrically mediated delivery of siRNA into muscle for gene function analysis
-
M. GolzioJ. Teissie. Optical in vivo imaging of electrically mediated delivery of siRNA into muscle for gene function analysis. Methods Mol Biol. 423:279-287 (2008)
-
(2008)
Methods Mol Biol
, vol.423
, pp. 279-287
-
-
Golzio, M.1
Teissie, J.2
-
141
-
-
77953132614
-
Liver-targeted siRNA delivery by polyethylenimine (PEI)-pullulan carrier
-
J.H. Kang, Y. Tachibana, W. Kamata, A. Mahara, M. Harada-Shiba, and T. Yamaoka. Liver-targeted siRNA delivery by polyethylenimine (PEI)-pullulan carrier. Bioorg Med Chem. 18:3946-3950 (2010)
-
(2010)
Bioorg Med Chem
, vol.18
, pp. 3946-3950
-
-
Kang, J.H.1
Tachibana, Y.2
Kamata, W.3
Mahara, A.4
Harada-Shiba, M.5
Yamaoka, T.6
|