Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells

Journal of the American Chemical Society

Volumn 127, Issue 6, 2005, Pages 1624-1625

  Oishi, Motoi ^a,d   Nagasaki, Yukio ^a,d   Itaka, Keiji ^b   Nishiyama, Nobuhiro ^c   Kataoka, Kazunori ^c  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MACROGOL; POLYCATION; SMALL INTERFERING RNA;

ARTICLE; BIOCOMPATIBILITY; CELL MEMBRANE PERMEABILITY; ENZYMATIC DEGRADATION; GENE SILENCING; HEPATOMA CELL; HUMAN; HUMAN CELL; HYDROPHILICITY; KIDNEY CLEARANCE; LIVER CLEARANCE; MICELLE; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; RNA INTERFERENCE; TARGET CELL;

CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; GENE TRANSFER TECHNIQUES; GENES, REPORTER; HUMANS; HYDROGEN-ION CONCENTRATION; LACTOSE; LIVER NEOPLASMS; LUCIFERASES; MICELLES; POLYETHYLENE GLYCOLS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 13644254495     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja044941d     Document Type: Article

References (19)

1. (a) Crooke, S. T. Biotechnol. Genet. Eng. Rev. 1998, 15, 121.
2. (b) Cook, P. D. Handb. Exp. Pharmacol. 1998, 131, 51.
3. Elbashir, S. M.; Harborth, J.; Lendeckel, W.; Yalcin, A.; Weber, K.; Tuschl, T. Nature 2001, 411, 494.
4. Taira, H. K. Nucleic Acid Res. 2003, 31, 700.
5. (c) Miyagishi, M.; Taira, K. Nat. Biotechnol. 2002, 20, 497.
6. Braasch, D.; Paroo, Z.; Constantiescu, A.; Ren, G.; Öz, O. K.; Mason, R. P.; Corey, D. R. Bioorg. Med. Chem. Lett. 2004, 14, 1139.
7. For selected examples, see: (a) Oishi, M.; Sasaki, S.; Nagasaki, Y.; Kataoka, K. Biomacromolecules 2003, 4, 1426. (b) Jeong, J. H.; Kim, S. W.; Park, T. G. Bioconjugate Chem. 2003, 14, 473. (c) Vinogradov, S. V.; Bronich, T. K.; Kabanov, A. V. Bioconjugate Chem. 1998, 9, 805. (d) Kataoka, K.; Togawa, H.; Harada, A.; Yasugi, K.; Matsumoto, T.; Katayose, S. Macromolecules 1996, 29, 8556. (e) Harada, A.; Kataoka, K. Macromolecules 1995, 28, 5294.
8. For selected examples, see: (a) Oishi, M.; Sasaki, S.; Nagasaki, Y.; Kataoka, K. Biomacromolecules 2003, 4, 1426. (b) Jeong, J. H.; Kim, S. W.; Park, T. G. Bioconjugate Chem. 2003, 14, 473. (c) Vinogradov, S. V.; Bronich, T. K.; Kabanov, A. V. Bioconjugate Chem. 1998, 9, 805. (d) Kataoka, K.; Togawa, H.; Harada, A.; Yasugi, K.; Matsumoto, T.; Katayose, S. Macromolecules 1996, 29, 8556. (e) Harada, A.; Kataoka, K. Macromolecules 1995, 28, 5294.
9. For selected examples, see: (a) Oishi, M.; Sasaki, S.; Nagasaki, Y.; Kataoka, K. Biomacromolecules 2003, 4, 1426. (b) Jeong, J. H.; Kim, S. W.; Park, T. G. Bioconjugate Chem. 2003, 14, 473. (c) Vinogradov, S. V.; Bronich, T. K.; Kabanov, A. V. Bioconjugate Chem. 1998, 9, 805. (d) Kataoka, K.; Togawa, H.; Harada, A.; Yasugi, K.; Matsumoto, T.; Katayose, S. Macromolecules 1996, 29, 8556. (e) Harada, A.; Kataoka, K. Macromolecules 1995, 28, 5294.
10. For selected examples, see: (a) Oishi, M.; Sasaki, S.; Nagasaki, Y.; Kataoka, K. Biomacromolecules 2003, 4, 1426. (b) Jeong, J. H.; Kim, S. W.; Park, T. G. Bioconjugate Chem. 2003, 14, 473. (c) Vinogradov, S. V.; Bronich, T. K.; Kabanov, A. V. Bioconjugate Chem. 1998, 9, 805. (d) Kataoka, K.; Togawa, H.; Harada, A.; Yasugi, K.; Matsumoto, T.; Katayose, S. Macromolecules 1996, 29, 8556. (e) Harada, A.; Kataoka, K. Macromolecules 1995, 28, 5294.
11. For selected examples, see: (a) Oishi, M.; Sasaki, S.; Nagasaki, Y.; Kataoka, K. Biomacromolecules 2003, 4, 1426. (b) Jeong, J. H.; Kim, S. W.; Park, T. G. Bioconjugate Chem. 2003, 14, 473. (c) Vinogradov, S. V.; Bronich, T. K.; Kabanov, A. V. Bioconjugate Chem. 1998, 9, 805. (d) Kataoka, K.; Togawa, H.; Harada, A.; Yasugi, K.; Matsumoto, T.; Katayose, S. Macromolecules 1996, 29, 8556. (e) Harada, A.; Kataoka, K. Macromolecules 1995, 28, 5294.
12. Wakebayashi, D.; Nishiyama, N.; Yamasaki, Y.; Itaka, K.; Kanayama, N.; Harada, A.; Nagasaki, Y.; Kataoka, K. J. Controlled Release 2004, 95, 653.
13. Schoenmakers, R. G.; van de Wetering, P.; Elbert, D. L.; Hubbell, J. A. J. Controlled Release 2004, 95, 291.
14. Wu, C. H.; Wu, G. Y. Adv. Drug Delivery Rev. 1998, 29, 243.
15. Itaka, K.; Kanayama, N.; Nishiyama, N.; Jang, W.-D.; Yamasaki, Y.; Nakamura, K.; Kawaguchi, H.; Kataoka, K. J. Am. Chem. Soc. 2004, 126, 13612.
16. Zanta, M. A.; Boussif, O.; Adib, A.; Behr, J. P. Bioconjugate Chem. 1997, 8, 839.
17. Uherek, C.; Fominaya, J.; Wels, W. J. Biol. Chem. 1998, 273, 8835.
18. Goh, S. L.; Murthy, N.; Xu, M.; Fréchet, J. M. J. Bioconjugate Chem. 2004, 15, 467.
19. Oishi, M.; Nagatsugi, F.; Sasaki, S.; Nagasaki, Y.; Kataoka, K. ChemBioChem. In press.