Internally cationic polyamidoamine PAMAM-OH dendrimers for siRNA delivery: Effect of the degree of Quaternization and cancer targeting

Biomacromolecules

Volumn 10, Issue 2, 2009, Pages 258-266

  Patil, Mahesh L ^a   Zhang, Min ^a   Taratula, Oleh ^b   Garbuzenko, Olga B ^a   He, Huixin ^b   Minko, Tamara ^a  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVERSE SIDE EFFECTS; BCL-2 GENES; CANCER CELLS; CANCER-TARGETING; CATIONIC CHARGES; DELIVERY SYSTEMS; IN-VITRO; INTRACELLULAR DELIVERIES; NANO CARRIERS; NANOMETER SIZES; POLYAMIDOAMINE; POLYAMIDOAMINE DENDRIMERS; PROTON SPONGES; QUATERNIZATION; SIRNA DELIVERIES; SPHERICAL PARTICLES; SYNTHETIC ANALOGS; TERTIARY AMINES;

AMINES; CELLS; CHEMOTHERAPY; CYTOTOXICITY; DYES;

DENDRIMERS;

DENDRIMER; GONADORELIN DERIVATIVE; NANOCARRIER; POLYAMIDOAMINE; SMALL INTERFERING RNA; TERTIARY AMINE; GONADORELIN; NANOPARTICLE; PAMAM STARBURST; POLYAMINE; QUATERNARY AMMONIUM DERIVATIVE;

ARTICLE; BCL2 GENE; CANCER CELL; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; PARTICLE SIZE; PRIORITY JOURNAL; PROTON TRANSPORT; CHEMISTRY; DRUG EFFECT; METHODOLOGY; NEOPLASM; PROTO ONCOGENE; TUMOR CELL LINE;

CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; GENES, BCL-2; GONADOTROPIN-RELEASING HORMONE; HUMANS; NANOPARTICLES; NEOPLASMS; POLYAMINES; QUATERNARY AMMONIUM COMPOUNDS; RNA, SMALL INTERFERING;

EID: 64149113037     PISSN: 15257797     EISSN: None     Source Type: Journal    
DOI: 10.1021/bm8009973     Document Type: Article

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