Functionalization of carbon nanotubes via cleavable disulfide bonds for efficient intracellular delivery of siRNA and potent gene silencing

Journal of the American Chemical Society

Volumn 127, Issue 36, 2005, Pages 12492-12493

  Kam, Nadine Wong Shi ^a   Liu, Zhuang ^a   Dai, Hongjie ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON NANOTUBE; NANOTUBE; SMALL INTERFERING RNA;

ARTICLE; DISULFIDE BOND; ENDOCYTOSIS; FUNCTIONAL ASSESSMENT; GENE SILENCING; INTRACELLULAR TRANSPORT; MAMMAL CELL; MOLECULAR BIOLOGY; RNA ANALYSIS; RNA INTERFERENCE; ULTRAVIOLET SPECTROSCOPY;

DISULFIDES; DNA; GENE SILENCING; HELA CELLS; HUMANS; MOLECULAR STRUCTURE; NANOTUBES, CARBON; PHOSPHOLIPIDS; RNA, SMALL INTERFERING; SENSITIVITY AND SPECIFICITY; SURFACE PROPERTIES; TRANSFECTION;

EID: 24744437125     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja053962k     Document Type: Article

References (8)

1. Kam, N. W. S.; Jessop, T. C.; Wender, P. A.; Dai, H. J. Am. Chem. Soc. 2004, 126, 6850-6851.
2. Kam, N. W. S.; Dai, H. J. Am. Chem. Soc. 2005, 127, 6021-6026.
3. Kam, N. W. S.; O'Connell, M.; Wisdom, J. A.; Dai, H. Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 11600-11605.
4. Bianco, A.; Kostarelos, K.; Partidos, C. D.; Prato, M. Chem. Commun. 2005, 5, 571-577.
5. Elbashir, S. M.; Harborth, J.; Lendeckel, W.; Yalcin, A.; Weber, K.; Tuschi, T. Nature 2001, 411, 495-498.
6. Gillies, E. R.; Fréchet, J. M. J. Bioconjugate Chem. 2005, 16, 361-368.
7. Arunachalam, B.; Phan, U. T.; Geuze, H. J.; Cresswell, P. Proc. Natl. Acad. Sci. U.S.A. 1999, 97, 745-750.
8. Patil, S. D.; Rhodes, D. G.; Burgess, D. J. AAPS J. 2005, 7, E61-E77.