-
1
-
-
15444367562
-
The vector void in gene therapy
-
Hodgson CP: The vector void in gene therapy. Biotechnol (1995) 13:222.
-
(1995)
Biotechnol
, vol.13
, pp. 222
-
-
Hodgson, C.P.1
-
2
-
-
0032605317
-
Pharmaceutical perspectives of non-viral gene therapy
-
Mahato RI, Smith LC, Rolland A: Pharmaceutical perspectives of non-viral gene therapy. Adv Genet (1999) 41. Comprehensive review on the pharmaceutical perspectives on gene expression plasmid, gene delivery systems, factors influencing gene transfer and biodistribution.
-
(1999)
Adv Genet
, vol.41
-
-
Mahato, R.I.1
Smith, L.C.2
Rolland, A.3
-
3
-
-
0004096115
-
-
Harwood Press
-
Rolland A (Ed): Advanced Gene Delivery: From Concepts to Pharmaceutical products. Harwood Press (1998). This book contains several comprehensive reviews on the pharmaceutical perspectives on plasmid-based gene medicines, including peptide-based gene delivery, DNA condensation and biodistribution.
-
(1998)
Advanced Gene Delivery: From Concepts to Pharmaceutical Products
-
-
Rolland, A.1
-
4
-
-
0030482720
-
Pharmaceutical approach to somatic gene therapy
-
Ledley FD: Pharmaceutical approach to somatic gene therapy. Pharm Res (1996) 13:1595-1614. Excellent review on the pharmaceutical approaches of plasmid-based gene delivery and expression.
-
(1996)
Pharm Res
, vol.13
, pp. 1595-1614
-
-
Ledley, F.D.1
-
5
-
-
0030890713
-
Non-viral vectors for in vivo gene delivery: Physicochemical and pharmacokinetic considerations
-
Mahato RI, Takakura Y, Hashida M: Non-viral vectors for in vivo gene delivery: physicochemical and pharmacokinetic considerations. Crit Rev Ther Drug Carrier Syst (1997) 14:133-172.
-
(1997)
Crit Rev Ther Drug Carrier Syst
, vol.14
, pp. 133-172
-
-
Mahato, R.I.1
Takakura, Y.2
Hashida, M.3
-
6
-
-
0023811723
-
Receptor-mediated gene delivery and expression in vivo
-
Wu GY, Wu CH: Receptor-mediated gene delivery and expression in vivo. J Biol Chem (1988) 263:14621-14624.
-
(1988)
J Biol Chem
, vol.263
, pp. 14621-14624
-
-
Wu, G.Y.1
Wu, C.H.2
-
7
-
-
0031566270
-
Gene transfer mediated by polyarginine requires a formation of big carrier-complex of DNA aggregate
-
Emi N, Kidoaki S, Yoshikawa K, Saito H: Gene transfer mediated by polyarginine requires a formation of big carrier-complex of DNA aggregate. Biochem Biophys Res Commun (1997) 231:421-424.
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 421-424
-
-
Emi, N.1
Kidoaki, S.2
Yoshikawa, K.3
Saito, H.4
-
8
-
-
0030895060
-
Lipospermine-mediated gene transfer technique in murine cultured cortical cells
-
Sola B, Staedel C, Remy JS, Behr A, Behr JP: Lipospermine-mediated gene transfer technique in murine cultured cortical cells. J Neurosci Methods (1997) 71:183-186.
-
(1997)
J Neurosci Methods
, vol.71
, pp. 183-186
-
-
Sola, B.1
Staedel, C.2
Remy, J.S.3
Behr, A.4
Behr, J.P.5
-
9
-
-
0029866353
-
Efficient gene transfer into mammalian cells with cholesteryl-spermidine
-
Moradpour D, Schauer JI, Zurawski VR Jr, Wands JR, Boutin RH: Efficient gene transfer into mammalian cells with cholesteryl-spermidine. Biochem Biophys Res Commun (1996) 221:82-88.
-
(1996)
Biochem Biophys Res Commun
, vol.221
, pp. 82-88
-
-
Moradpour, D.1
Schauer, J.I.2
Zurawski Jr., V.R.3
Wands, J.R.4
Boutin, R.H.5
-
10
-
-
0030775528
-
The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes
-
Tang MX, Szoka FC: The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther (1997) 4:823-832. The SAR of a series of cationic polymers for in vitro transfection of cultured cells.
-
(1997)
Gene Ther
, vol.4
, pp. 823-832
-
-
Tang, M.X.1
Szoka, F.C.2
-
11
-
-
0032484162
-
Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery
-
MacLaughlin FC, Mumper RJ, Wang J, Tagliaferri JM, Hinchcliffe M, Rolland AP: Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery. J Control Rel (1998) 56:259-272.
-
(1998)
J Control Rel
, vol.56
, pp. 259-272
-
-
MacLaughlin, F.C.1
Mumper, R.J.2
Wang, J.3
Tagliaferri, J.M.4
Hinchcliffe, M.5
Rolland, A.P.6
-
12
-
-
0029799791
-
A powerful nonviral vector for in vitro gene transfer into the adult mammalian brain: Polyethyleneimine
-
Abdallan B, Hassan A, Benoist C, Goula D, Behr JP, Demeneix BA: A powerful nonviral vector for in vitro gene transfer into the adult mammalian brain: polyethyleneimine. Hum Gene Ther (1996) 7:1947-1954.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1947-1954
-
-
Abdallan, B.1
Hassan, A.2
Benoist, C.3
Goula, D.4
Behr, J.P.5
Demeneix, B.A.6
-
14
-
-
0023447252
-
Lipofectin: A highly efficient, lipid-mediated DNA-transfection procedure
-
Felgner PL, Gadek TR, Holm M, Roman R, Chan HW, Wenz M, Northrop JP, Ringold GM, Danielsen M: Lipofectin: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA (1987) 84:7413-7417.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7413-7417
-
-
Felgner, P.L.1
Gadek, T.R.2
Holm, M.3
Roman, R.4
Chan, H.W.5
Wenz, M.6
Northrop, J.P.7
Ringold, G.M.8
Danielsen, M.9
-
15
-
-
0032501104
-
Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes
-
Kawakami S, Yamashita F, Nishikawa M, Takakura Y, Hashida M: Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes. Biochem Biophys Res Commun (1998) 252:78-83.
-
(1998)
Biochem Biophys Res Commun
, vol.252
, pp. 78-83
-
-
Kawakami, S.1
Yamashita, F.2
Nishikawa, M.3
Takakura, Y.4
Hashida, M.5
-
16
-
-
0031976511
-
Nuclear localization signal peptides enhance cationic liposome-mediated gene therapy
-
Aronsohn AI, Hughes JA: Nuclear localization signal peptides enhance cationic liposome-mediated gene therapy. J Drug Target (1998) 5:163-169.
-
(1998)
J Drug Target
, vol.5
, pp. 163-169
-
-
Aronsohn, A.I.1
Hughes, J.A.2
-
17
-
-
0030566148
-
Complexes of non-cationic liposomes and histone H1 mediate efficient transfection of DNA without encapsulation
-
Hagstrom JE, Sebestyen MG, Budker V, Ludtke JJ, Fritz JD, Wolff JA: Complexes of non-cationic liposomes and histone H1 mediate efficient transfection of DNA without encapsulation. Biochim Biophys Acta (1996) 1284:47-55.
-
(1996)
Biochim Biophys Acta
, vol.1284
, pp. 47-55
-
-
Hagstrom, J.E.1
Sebestyen, M.G.2
Budker, V.3
Ludtke, J.J.4
Fritz, J.D.5
Wolff, J.A.6
-
18
-
-
0032473403
-
Synthetic peptide-based DNA complexes for nonviral gene delivery
-
Smith LC, Duguid JG, Wadhwa MS, Logan MJ, Tung C-H, Edwards V, Sparrow JT: Synthetic peptide-based DNA complexes for nonviral gene delivery. Adv Drug Del Rel (1998) 30:115-131. Excellent review on condensing and endosomolytic peptides, intracellular trafficking and nuclear entry of plasmids.
-
(1998)
Adv Drug Del Rel
, vol.30
, pp. 115-131
-
-
Smith, L.C.1
Duguid, J.G.2
Wadhwa, M.S.3
Logan, M.J.4
Tung, C.-H.5
Edwards, V.6
Sparrow, J.T.7
-
19
-
-
0031447208
-
DNA condensation by multivalent cations
-
Bloomfield VA: DNA condensation by multivalent cations. Biopolymers (1998) 44:269-282. Excellent review that discusses agents, morphology of condensed states, kinetics and reversibility of DNA condensation, and the statistical mechanics of DNA collapse.
-
(1998)
Biopolymers
, vol.44
, pp. 269-282
-
-
Bloomfield, V.A.1
-
20
-
-
0029937426
-
DNA condensation
-
Bloomfield VA: DNA condensation. Curr Opin Struct Biol (1996) 6:334-341. Impressive, excellent and comprehensive review on DNA condensation, which discusses how a multivalent cation drives DNA condensation.
-
(1996)
Curr Opin Struct Biol
, vol.6
, pp. 334-341
-
-
Bloomfield, V.A.1
-
21
-
-
0026253815
-
Condensation of DNA by multivalent cations: Considerations on mechanism
-
Bloomfield VA: Condensation of DNA by multivalent cations: considerations on mechanism. Bioploymers (1991) 31:1471-1481.
-
(1991)
Bioploymers
, vol.31
, pp. 1471-1481
-
-
Bloomfield, V.A.1
-
22
-
-
0027317135
-
Identification of the elemental packing unit of DNA in mammalian sperm cells by atomic force microscopy
-
Hud NV, Allen MJ, Downing KH, Lee J, Balhorn R: Identification of the elemental packing unit of DNA in mammalian sperm cells by atomic force microscopy. Biochem Biophys Res Commun (1993) 193:1347-1354.
-
(1993)
Biochem Biophys Res Commun
, vol.193
, pp. 1347-1354
-
-
Hud, N.V.1
Allen, M.J.2
Downing, K.H.3
Lee, J.4
Balhorn, R.5
-
24
-
-
0025066887
-
Condensation of DNA by trivalent cations. 1. Effects of DNA length and topology on the size and shape of condensed particles
-
Arscott PG, Li AZ, Bloomfield VA: Condensation of DNA by trivalent cations. 1. Effects of DNA length and topology on the size and shape of condensed particles. Biopolymers (1990) 30:619-630.
-
(1990)
Biopolymers
, vol.30
, pp. 619-630
-
-
Arscott, P.G.1
Li, A.Z.2
Bloomfield, V.A.3
-
25
-
-
0018803816
-
Counterion-induced condensation of deoxyribonucleic acid, a light scattering study
-
Wilson RW, Bloomfield VA: Counterion-induced condensation of deoxyribonucleic acid, a light scattering study. Biochemistry (1979) 18:2192-2196.
-
(1979)
Biochemistry
, vol.18
, pp. 2192-2196
-
-
Wilson, R.W.1
Bloomfield, V.A.2
-
26
-
-
0015802422
-
Regular superstructures of purified DNA in ethanolic solutions
-
Lang D: Regular superstructures of purified DNA in ethanolic solutions. J Mol Biol (1973) 78:247-254.
-
(1973)
J Mol Biol
, vol.78
, pp. 247-254
-
-
Lang, D.1
-
27
-
-
0017837314
-
The compaction of DNA helices into either continuous supercoils or folded-fiber rods and toroids
-
Eickbush TH, Moundrianakis EN: The compaction of DNA helices into either continuous supercoils or folded-fiber rods and toroids. Cell (1978) 13:295-306.
-
(1978)
Cell
, vol.13
, pp. 295-306
-
-
Eickbush, T.H.1
Moundrianakis, E.N.2
-
28
-
-
0025034805
-
Structural and electrostatic effects on binding of trivalent cations to double-stranded and single-stranded poly[d(AT)]
-
Plum GE, Bloomfield VA: Structural and electrostatic effects on binding of trivalent cations to double-stranded and single-stranded poly[d(AT)]. Biopolymers (1990) 29:13-27.
-
(1990)
Biopolymers
, vol.29
, pp. 13-27
-
-
Plum, G.E.1
Bloomfield, V.A.2
-
29
-
-
0015100570
-
A transition to a compact form of DNA in polymer solutions
-
Lerman LS: A transition to a compact form of DNA in polymer solutions. Proc Natl Acad Sci USA (1971) 68:1886-1890.
-
(1971)
Proc Natl Acad Sci USA
, vol.68
, pp. 1886-1890
-
-
Lerman, L.S.1
-
30
-
-
0016363138
-
Maturation of the head of bacteriophage T4. V. a possible DNA packaging mechanism: In vitro cleavage of the head proteins and the structures of the core of the polyhead
-
Laemmli UK, Paulson JR, Hitchins V: Maturation of the head of bacteriophage T4. V. A possible DNA packaging mechanism: in vitro cleavage of the head proteins and the structures of the core of the polyhead. J Supramol Struct (1974) 2:276-301.
-
(1974)
J Supramol Struct
, vol.2
, pp. 276-301
-
-
Laemmli, U.K.1
Paulson, J.R.2
Hitchins, V.3
-
31
-
-
0032539538
-
Monomolecular collapse of plasmid DNA into stable virus-like particles
-
Blessing T, Remy JS, Behr JP: Monomolecular collapse of plasmid DNA into stable virus-like particles. Proc Natl Acad Sci USA (1998) 95:1427-1431. Illustrates the development of negatively charged DNA-containing monodisperse 23 nm size particles, which were stable on oxidation.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1427-1431
-
-
Blessing, T.1
Remy, J.S.2
Behr, J.P.3
-
32
-
-
0025744180
-
Thermodynamics of cation-induced DNA condensation
-
Manquet R, Houssier C: Thermodynamics of cation-induced DNA condensation. J Biomol Struct Dyn (1991) 9:159-167.
-
(1991)
J Biomol Struct Dyn
, vol.9
, pp. 159-167
-
-
Manquet, R.1
Houssier, C.2
-
33
-
-
0028922318
-
Diaminoalkanes with an odd number of carbon atoms induce compaction of a single double-stranded DNA chain
-
Yoshikawa Y, Yoshikawa K: Diaminoalkanes with an odd number of carbon atoms induce compaction of a single double-stranded DNA chain. FEBS Lett (1995) 361:277-281.
-
(1995)
FEBS Lett
, vol.361
, pp. 277-281
-
-
Yoshikawa, Y.1
Yoshikawa, K.2
-
34
-
-
0030918597
-
Binding of cationic alpha-helical peptides to plasmid DNA and their gene transfer abilities into cells
-
Niidome T, Ohmori N, Ichinose A, Wada A, Mihara H, Hirayama T, Aoyagi H: Binding of cationic alpha-helical peptides to plasmid DNA and their gene transfer abilities into cells. J Biol Chem (1997) 272:15307-15312.
-
(1997)
J Biol Chem
, vol.272
, pp. 15307-15312
-
-
Niidome, T.1
Ohmori, N.2
Ichinose, A.3
Wada, A.4
Mihara, H.5
Hirayama, T.6
Aoyagi, H.7
-
35
-
-
0029941321
-
A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells
-
OR 48-57
-
Gottschalk S, Sparrow JT, Hauer J, Mims MP, Leland FE, Woo SL, Smith LC: A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells. Gene Ther (1996) 3:448-457. OR 48-57. This study investigates the design and in vitro characterization of synthetic peptides for gene delivery.
-
(1996)
Gene Ther
, vol.3
, pp. 448-457
-
-
Gottschalk, S.1
Sparrow, J.T.2
Hauer, J.3
Mims, M.P.4
Leland, F.E.5
Woo, S.L.6
Smith, L.C.7
-
37
-
-
0030952671
-
n hydrazide as an efficient gene transfer vector in mammalian cells in culture
-
n hydrazide as an efficient gene transfer vector in mammalian cells in culture. Pharm Res (1997) 14:619-624. This study investigates the SAR of a series of N-acyl peptides (lipopeptides) for in vitro transfection of mammalian cells.
-
(1997)
Pharm Res
, vol.14
, pp. 619-624
-
-
Legendre, J.Y.1
Trzeciak, A.2
Bur, D.3
Deuschle, U.4
Supersaxo, A.5
-
38
-
-
0029136052
-
DNA complexes with polycations for the delivery of genetic materials into cells
-
Kabanov AV, Kabanov VA: DNA complexes with polycations for the delivery of genetic materials into cells. Bioconjug Chem (1995) 6:7-20. Excellent review on polycation-based gene delivery and DNA condensation.
-
(1995)
Bioconjug Chem
, vol.6
, pp. 7-20
-
-
Kabanov, A.V.1
Kabanov, V.A.2
-
39
-
-
0031806722
-
A physicochemical approach for predicting the effectiveness of peptide-based gene delivery systems for use in plasmid-based gene therapy
-
Duguid JG, Li C, Shi M, Logan MJ, Alila H, Rolland A, Tomlinson E, Sparrow JT, Smith LC: A physicochemical approach for predicting the effectiveness of peptide-based gene delivery systems for use in plasmid-based gene therapy. Biophys J (1998) 74:2802-2814. Linear correlation between various physicochemical properties of peptide/plasmid complexes and in vitro transfection.
-
(1998)
Biophys J
, vol.74
, pp. 2802-2814
-
-
Duguid, J.G.1
Li, C.2
Shi, M.3
Logan, M.J.4
Alila, H.5
Rolland, A.6
Tomlinson, E.7
Sparrow, J.T.8
Smith, L.C.9
-
40
-
-
0024343077
-
Targeting genes: Delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo
-
Wu CH, Wilson JM, Wu GY: Targeting genes: delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo. J Biol Chem (1989) 264:16985-16987.
-
(1989)
J Biol Chem
, vol.264
, pp. 16985-16987
-
-
Wu, C.H.1
Wilson, J.M.2
Wu, G.Y.3
-
41
-
-
0025340966
-
Transferrin-polycation conjugates as carriers for DNA uptake into cells
-
Wagner E, Zenke M, Cotten M, Beug H, Birnstiel ML: Transferrin-polycation conjugates as carriers for DNA uptake into cells. Proc Natl Acad Sci USA (1990) 87:3410-3414.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 3410-3414
-
-
Wagner, E.1
Zenke, M.2
Cotten, M.3
Beug, H.4
Birnstiel, M.L.5
-
42
-
-
0028168773
-
Galactosylated histone-mediated gene transfer and expression
-
Chen J, Stickles RJ, Daichendt KA: Galactosylated histone-mediated gene transfer and expression. Hum Gene Ther (1994) 5:449-435.
-
(1994)
Hum Gene Ther
, vol.5
, pp. 449-1435
-
-
Chen, J.1
Stickles, R.J.2
Daichendt, K.A.3
-
43
-
-
0027365343
-
Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor
-
Ferkol T, Kaetzel CS, Davis PB: Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor. J Clin Invest (1993) 92:2394-2400.
-
(1993)
J Clin Invest
, vol.92
, pp. 2394-2400
-
-
Ferkol, T.1
Kaetzel, C.S.2
Davis, P.B.3
-
44
-
-
0025352717
-
Evidence for targeted gene transfer by receptor-mediated endocytosis. Stable expression following insulin-directed entry of NEO into HepG2 cells
-
Huckett B, Ariatti M, Hawtrey AO: Evidence for targeted gene transfer by receptor-mediated endocytosis. Stable expression following insulin-directed entry of NEO into HepG2 cells. Biochem Pharmacol (1990) 40:253-263.
-
(1990)
Biochem Pharmacol
, vol.40
, pp. 253-263
-
-
Huckett, B.1
Ariatti, M.2
Hawtrey, A.O.3
-
45
-
-
0027954666
-
A novel gene delivery system using EGF receptor-mediated endocytosis
-
Chen J, Gamou S, Takayanagi A, Shimizu N: A novel gene delivery system using EGF receptor-mediated endocytosis. FEBS Lett (1994) 338:167-169.
-
(1994)
FEBS Lett
, vol.338
, pp. 167-169
-
-
Chen, J.1
Gamou, S.2
Takayanagi, A.3
Shimizu, N.4
-
46
-
-
0028067878
-
Lectin conjugate-directed gene transfer to airway epithelial cells
-
Cheng PW, Yin W: Lectin conjugate-directed gene transfer to airway epithelial cells. Biochem Biophys Res Commun (1994) 205:826-833.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 826-833
-
-
Cheng, P.W.1
Yin, W.2
-
47
-
-
0028430957
-
Folate receptor-mediated DNA delivery into tumor cells: Potosomal disruption results in enhanced gene expression
-
Gottschalk S, Cristiano RJ, Smith LC, Woo SL: Folate receptor-mediated DNA delivery into tumor cells: potosomal disruption results in enhanced gene expression. Gene Ther (1994) 1:185-191.
-
(1994)
Gene Ther
, vol.1
, pp. 185-191
-
-
Gottschalk, S.1
Cristiano, R.J.2
Smith, L.C.3
Woo, S.L.4
-
48
-
-
0028954476
-
Malarial circumsporozoite protein is a novel gene delivery vehicle to primary hepatocyte cultures and cultured cells
-
Ding ZM, Cristiano RJ, Roth JA, Takacs B, Kuo MT: Malarial circumsporozoite protein is a novel gene delivery vehicle to primary hepatocyte cultures and cultured cells. J Biol Chem (1995) 270:3667-3676.
-
(1995)
J Biol Chem
, vol.270
, pp. 3667-3676
-
-
Ding, Z.M.1
Cristiano, R.J.2
Roth, J.A.3
Takacs, B.4
Kuo, M.T.5
-
50
-
-
0028982477
-
Receptor-mediated gene transfer into human T lymphocytes via binding of DNA/CD3 antibody particles to the CD3 T cell receptor complex
-
Buschle M, Cotten M, Kirlappos H, Mechtler K, Schaffner G, Zauner W, Birnstiel ML, Wagner E: Receptor-mediated gene transfer into human T lymphocytes via binding of DNA/CD3 antibody particles to the CD3 T cell receptor complex. Hum Gene Ther (1995) 6:753-761.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 753-761
-
-
Buschle, M.1
Cotten, M.2
Kirlappos, H.3
Mechtler, K.4
Schaffner, G.5
Zauner, W.6
Birnstiel, M.L.7
Wagner, E.8
-
51
-
-
0029328597
-
Glycosylated polylysine/DNA complexes: Gene transfer efficiency in relation with the size and the sugar substitution level of glycosylated polylysines and with the plasmid size
-
Erbacher P, Roche AC, Monsigny M, Midoux P: Glycosylated polylysine/DNA complexes: gene transfer efficiency in relation with the size and the sugar substitution level of glycosylated polylysines and with the plasmid size. Bioconjug Chem (1995) 6:401-410.
-
(1995)
Bioconjug Chem
, vol.6
, pp. 401-410
-
-
Erbacher, P.1
Roche, A.C.2
Monsigny, M.3
Midoux, P.4
-
52
-
-
0027933122
-
Carbohydrate receptor-mediated gene transfer to human T leukaemic cells
-
Thumher M, Wagner E, Clausen H, Mechtler K, Rusconi S, Dinter A, Birnstiel ML, Berger EG, Cotton M: Carbohydrate receptor-mediated gene transfer to human T leukaemic cells. Glycobiology (1994) 4:429-435.
-
(1994)
Glycobiology
, vol.4
, pp. 429-435
-
-
Thumher, M.1
Wagner, E.2
Clausen, H.3
Mechtler, K.4
Rusconi, S.5
Dinter, A.6
Birnstiel, M.L.7
Berger, E.G.8
Cotton, M.9
-
53
-
-
0028790759
-
Gene delivery and expression mediated by an integrin-binding peptide
-
Hart SL, Harbottle RP, Cooper R, Miller A, Williamson R, Couttele C: Gene delivery and expression mediated by an integrin-binding peptide. Gene Ther (1995) 2:552-554.
-
(1995)
Gene Ther
, vol.2
, pp. 552-554
-
-
Hart, S.L.1
Harbottle, R.P.2
Cooper, R.3
Miller, A.4
Williamson, R.5
Couttele, C.6
-
54
-
-
0026891048
-
Use of N-terminal modified poly(L-lysine)-antibody conjugate as a carrier for targeted gene delivery in mouse lung endothelial cells
-
Trubetskoy VS, Torchilin VP, Kennel SJ, Huang L: Use of N-terminal modified poly(L-lysine)-antibody conjugate as a carrier for targeted gene delivery in mouse lung endothelial cells. Bioconjug Chem (1992) 3:323-327.
-
(1992)
Bioconjug Chem
, vol.3
, pp. 323-327
-
-
Trubetskoy, V.S.1
Torchilin, V.P.2
Kennel, S.J.3
Huang, L.4
-
55
-
-
0028989345
-
Surfactant protein A-polylysine conjugates for delivery of DNA to airway cells in culture
-
Ross GF, Morris RE, Ciraolo G, Huelsman K, Bruno M, Whitsett JA, Baatz JA, Korfthagen TR: Surfactant protein A-polylysine conjugates for delivery of DNA to airway cells in culture. Hum Gene Ther (1995) 6:31-40.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 31-40
-
-
Ross, G.F.1
Morris, R.E.2
Ciraolo, G.3
Huelsman, K.4
Bruno, M.5
Whitsett, J.A.6
Baatz, J.A.7
Korfthagen, T.R.8
-
56
-
-
0028301813
-
Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture
-
Baatz JE, Bruno MD, Ciraolo PJ, Glasser SW, Stripp BR, Smyth KL, Korfhagen TR: Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture. Proc Natl Acad Sci USA (1994) 91:2547-2551.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2547-2551
-
-
Baatz, J.E.1
Bruno, M.D.2
Ciraolo, P.J.3
Glasser, S.W.4
Stripp, B.R.5
Smyth, K.L.6
Korfhagen, T.R.7
-
57
-
-
0030069992
-
Targeted gene transfer to human hematopoietic progenitor cell lines through the c-kit receptor
-
Schwarzenberger P, Spence SE, Gooya JM, Michiel D, Curiel DT, Ruscetti FW, Keller JR: Targeted gene transfer to human hematopoietic progenitor cell lines through the c-kit receptor. Blood (1996) 87:472-478.
-
(1996)
Blood
, vol.87
, pp. 472-478
-
-
Schwarzenberger, P.1
Spence, S.E.2
Gooya, J.M.3
Michiel, D.4
Curiel, D.T.5
Ruscetti, F.W.6
Keller, J.R.7
-
59
-
-
0029789066
-
Cyclic RGD peptides containing β-turn mimetics
-
Haubner R, Schmitt W, Hölzemann G, Goodman SL, Joncysk A, Kessler H: Cyclic RGD peptides containing β-turn mimetics. J Am Chem (1996) 118:7881-7891.
-
(1996)
J Am Chem
, vol.118
, pp. 7881-7891
-
-
Haubner, R.1
Schmitt, W.2
Hölzemann, G.3
Goodman, S.L.4
Joncysk, A.5
Kessler, H.6
-
60
-
-
0030940283
-
αv integrins as receptors for tumor targeting by circulating ligands
-
Pasqualini R, Koivunen E, Ruoslahti E: αv integrins as receptors for tumor targeting by circulating ligands. Nat Biotechnol (1997) 15:542-546. Demonstration of the tumor-specific gene delivery and expression after tail vein injection of RGD peptide/plasmid complexes into tumor-bearing mice.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 542-546
-
-
Pasqualini, R.1
Koivunen, E.2
Ruoslahti, E.3
-
61
-
-
0032077216
-
An RGD-oligolysine peptide: A prototype construct for integrin-mediated gene delivery
-
Harbottle RP, Cooper RG, Hart SL, Ladhoff A, McKay T, Knight AM, Wagner E, Miller AD, Couteile C: An RGD-oligolysine peptide: a prototype construct for integrin-mediated gene delivery. Hum Gene Ther (1998) 9:1037-1047.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 1037-1047
-
-
Harbottle, R.P.1
Cooper, R.G.2
Hart, S.L.3
Ladhoff, A.4
McKay, T.5
Knight, A.M.6
Wagner, E.7
Miller, A.D.8
Couteile, C.9
-
62
-
-
0029294596
-
Targeted gene delivery with a low molecular weight glycopeptide carrier
-
Wadhwa MS, Knoell DL, Young AP, Rice KG: Targeted gene delivery with a low molecular weight glycopeptide carrier. Bioconjug Chem (1995) 6:283-291.
-
(1995)
Bioconjug Chem
, vol.6
, pp. 283-291
-
-
Wadhwa, M.S.1
Knoell, D.L.2
Young, A.P.3
Rice, K.G.4
-
63
-
-
0028365876
-
In vivo targeting function of N-linked oligosaccharides with terminating galactose and N-acetylgalactosamine residues
-
Chiu MH, Tamura T, Wadhwa MS, Rice KG: In vivo targeting function of N-linked oligosaccharides with terminating galactose and N-acetylgalactosamine residues. J Biol Sci (1994) 269:16195-16202.
-
(1994)
J Biol Sci
, vol.269
, pp. 16195-16202
-
-
Chiu, M.H.1
Tamura, T.2
Wadhwa, M.S.3
Rice, K.G.4
-
64
-
-
0026952599
-
Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand
-
Plank C, Zatloukal K, Cotten M, Mechtler K, Wagner E: Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand. Bioconjug Chem (1992) 3:533-539.
-
(1992)
Bioconjug Chem
, vol.3
, pp. 533-539
-
-
Plank, C.1
Zatloukal, K.2
Cotten, M.3
Mechtler, K.4
Wagner, E.5
-
65
-
-
0028223310
-
Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake
-
Perales JC, Ferkol T, Beegen H, Ratnoff OD, Hanson RW: Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake. Proc Natl Acad Sci USA (1994) 91:4086-4090.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4086-4090
-
-
Perales, J.C.1
Ferkol, T.2
Beegen, H.3
Ratnoff, O.D.4
Hanson, R.W.5
-
67
-
-
0030002508
-
Controllable gene therapy: Pharmaceutics of non-viral gene delivery systems
-
Tomlinson E, Rolland A: Controllable gene therapy: Pharmaceutics of non-viral gene delivery systems. J Control Rel (1996) 39:357-372.
-
(1996)
J Control Rel
, vol.39
, pp. 357-372
-
-
Tomlinson, E.1
Rolland, A.2
-
68
-
-
0342917249
-
Biological barriers to gene transfer
-
Rolland A (Ed), Harwood Press
-
Pouton CW: Biological barriers to gene transfer. In: Advanced Gene Delivery: From Concepts to Pharmaceutical Products. Rolland A (Ed), Harwood Press (1998):65-102. Comprehensive review on biodistribution, cellular uptake and intracellular trafficking of gene expression plasmids.
-
(1998)
Advanced Gene Delivery: From Concepts to Pharmaceutical Products
, pp. 65-102
-
-
Pouton, C.W.1
-
69
-
-
0023654706
-
Membrane binding and conformational properties of peptides representing the NH2 terminus of influenza HA-2
-
Lear JD, DeGrado WF: Membrane binding and conformational properties of peptides representing the NH2 terminus of influenza HA-2. J Biol Chem (1987) 262:6500-6505.
-
(1987)
J Biol Chem
, vol.262
, pp. 6500-6505
-
-
Lear, J.D.1
DeGrado, W.F.2
-
70
-
-
0025719093
-
Membrane fusion activity of the influenza virus hemagglutinin: Interaction of HA2 N-terminal peptides with phospholipid vesicles
-
Rafalski M, Ortiz A, Rockwell A, van Ginkel LC, Lear JD, DeGrado WF, Wilschut J: Membrane fusion activity of the influenza virus hemagglutinin: interaction of HA2 N-terminal peptides with phospholipid vesicles. Biochemistry (1991) 30:10211-10220.
-
(1991)
Biochemistry
, vol.30
, pp. 10211-10220
-
-
Rafalski, M.1
Ortiz, A.2
Rockwell, A.3
Van Ginkel, L.C.4
Lear, J.D.5
DeGrado, W.F.6
Wilschut, J.7
-
71
-
-
0032487377
-
Application of membrane-active peptides for drug and gene delivery across cellular membrane
-
Plank C, Zauner W, Wagner E: Application of membrane-active peptides for drug and gene delivery across cellular membrane. Adv Drug Del Rev (1998) 34:21-35. Excellent review on peptide-based gene delivery, especially on membrane destabilization and nuclear localization.
-
(1998)
Adv Drug Del Rev
, vol.34
, pp. 21-35
-
-
Plank, C.1
Zauner, W.2
Wagner, E.3
-
72
-
-
0030041468
-
Structural study of the interaction between the SIV fusion peptide and model membranes
-
Colotto A, Martin I, Ruysschaert JM, Sen A, Hui SW, Epand RM: Structural study of the interaction between the SIV fusion peptide and model membranes. Biochemistry (1996) 35:980-989.
-
(1996)
Biochemistry
, vol.35
, pp. 980-989
-
-
Colotto, A.1
Martin, I.2
Ruysschaert, J.M.3
Sen, A.4
Hui, S.W.5
Epand, R.M.6
-
73
-
-
0030971376
-
Sizing membrane pores in lipid vesicles by leakage of co-encapsulated markers: Pore formation by melittin
-
Ladokhin AS, Selsted ME, White SH: Sizing membrane pores in lipid vesicles by leakage of co-encapsulated markers: pore formation by melittin. Biophys J (1997) 72:1762-1766.
-
(1997)
Biophys J
, vol.72
, pp. 1762-1766
-
-
Ladokhin, A.S.1
Selsted, M.E.2
White, S.H.3
-
74
-
-
0029146071
-
Mechanisms for the modulation of membrane bilayer properties by amphipathic helical peptides
-
Epand RM, Shai Y, Segrest JP, Anantharamaiah GM: Mechanisms for the modulation of membrane bilayer properties by amphipathic helical peptides. Biopolymers (1995) 37:319-338.
-
(1995)
Biopolymers
, vol.37
, pp. 319-338
-
-
Epand, R.M.1
Shai, Y.2
Segrest, J.P.3
Anantharamaiah, G.M.4
-
75
-
-
0028178521
-
Pore-forming peptides induce rapid phospholipid flip-flop in membranes
-
Fattal E, Nir S, Parente RA, Szoka FC Jr: Pore-forming peptides induce rapid phospholipid flip-flop in membranes. Biochemistry (1994) 33:6721-6731.
-
(1994)
Biochemistry
, vol.33
, pp. 6721-6731
-
-
Fattal, E.1
Nir, S.2
Parente, R.A.3
Szoka Jr., F.C.4
-
76
-
-
0026655684
-
Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: Toward a synthetic virus-like gene transfer vehicle
-
Wagner E, Plank C, Zatloukal K, Cotton M, Birnstiel ML: Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene transfer vehicle. Proc Natl Acad Sci USA (1992) 89:7934-7938.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7934-7938
-
-
Wagner, E.1
Plank, C.2
Zatloukal, K.3
Cotton, M.4
Birnstiel, M.L.5
-
77
-
-
0027076361
-
Transferrinfection: A highly efficient way to express gene constructs in eukaryotic cells
-
Zatloukal K, Wagner E, Cotten M, Phillips S, Plank C, Steinlein P, Curiel DT, Birnsteil ML: Transferrinfection: a highly efficient way to express gene constructs in eukaryotic cells. Ann NY Acad Sci (1992) 660:136-153.
-
(1992)
Ann NY Acad Sci
, vol.660
, pp. 136-153
-
-
Zatloukal, K.1
Wagner, E.2
Cotten, M.3
Phillips, S.4
Plank, C.5
Steinlein, P.6
Curiel, D.T.7
Birnsteil, M.L.8
-
78
-
-
0032580528
-
Effects of membrane-active agents in gene delivery
-
Wagner E: Effects of membrane-active agents in gene delivery. J Control Rel (1998) 53:155-158.
-
(1998)
J Control Rel
, vol.53
, pp. 155-158
-
-
Wagner, E.1
-
79
-
-
0031104992
-
Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer
-
Kichler A, Mechtler K, Behr JP, Wagner E: Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer. Bioconjug Chem (1997) 8:213-221. Demonstrated significant enhancement in gene transfer by using lipids in combination with endosomolytic peptides.
-
(1997)
Bioconjug Chem
, vol.8
, pp. 213-221
-
-
Kichler, A.1
Mechtler, K.2
Behr, J.P.3
Wagner, E.4
-
80
-
-
0027995873
-
α-helical properties of amino acids in the hydrophobic face of an amphipathic α-helix
-
Zhou NE, Monera OD, Kay CM, Hodges RS: α-helical properties of amino acids in the hydrophobic face of an amphipathic α-helix. Protein Peptide Lett (1994) 1:114-119.
-
(1994)
Protein Peptide Lett
, vol.1
, pp. 114-119
-
-
Zhou, N.E.1
Monera, O.D.2
Kay, C.M.3
Hodges, R.S.4
-
81
-
-
0029361842
-
Relationship of side chain hydrophobicity and α-helical propensity on the stability of the single-stranded amphipathic α-helix
-
Monera OD, Sereda TJ, Zhou NE, Kay CM, Hodges RS: Relationship of side chain hydrophobicity and α-helical propensity on the stability of the single-stranded amphipathic α-helix. J Pept Sci (1995) 1:319-329.
-
(1995)
J Pept Sci
, vol.1
, pp. 319-329
-
-
Monera, O.D.1
Sereda, T.J.2
Zhou, N.E.3
Kay, C.M.4
Hodges, R.S.5
-
82
-
-
0028805884
-
The effects of interhelical electrostatic repulsions between glutamic acid residues in controlling the dimerization and stability of two-stranded α-helical coiled-coils
-
Kohn WD, Monera OD, Kay CM, Hodges RS: The effects of interhelical electrostatic repulsions between glutamic acid residues in controlling the dimerization and stability of two-stranded α-helical coiled-coils. J Biol Chem (1995) 270:25495-25506.
-
(1995)
J Biol Chem
, vol.270
, pp. 25495-25506
-
-
Kohn, W.D.1
Monera, O.D.2
Kay, C.M.3
Hodges, R.S.4
-
83
-
-
0023642299
-
pH-dependent bilayer destabilization by an amphipathic peptide
-
Subbarao NK, Parente RA, Szoka FC Jr, Nadasdi L, Pongracz K: pH-dependent bilayer destabilization by an amphipathic peptide. Biochemistry (1987) 26:2964-2972.
-
(1987)
Biochemistry
, vol.26
, pp. 2964-2972
-
-
Subbarao, N.K.1
Parente, R.A.2
Szoka Jr., F.C.3
Nadasdi, L.4
Pongracz, K.5
-
84
-
-
0023883581
-
pH-dependent fusion of phosphatidylcholine small vesicles. Induction by a synthetic amphipathic peptide
-
Parente RA, Nir S, Szoka FC Jr: pH-dependent fusion of phosphatidylcholine small vesicles. Induction by a synthetic amphipathic peptide. J Biol Chem (1988) 263:4724-4730.
-
(1988)
J Biol Chem
, vol.263
, pp. 4724-4730
-
-
Parente, R.A.1
Nir, S.2
Szoka Jr., F.C.3
-
85
-
-
0025042733
-
Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA
-
Parente RA, Nir S, Szoka FC Jr: Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA. Biochemistry (1990) 29:8720-8728.
-
(1990)
Biochemistry
, vol.29
, pp. 8720-8728
-
-
Parente, R.A.1
Nir, S.2
Szoka Jr., F.C.3
-
86
-
-
0024996257
-
Association of a pH-sensitive peptide with membrane vesicles: Role of amino acid sequence
-
Parente RA, Nadasdi L, Subbarao NK, Szoka FC Jr: Association of a pH-sensitive peptide with membrane vesicles: role of amino acid sequence. Biochemistry (1990) 29:8713-8719.
-
(1990)
Biochemistry
, vol.29
, pp. 8713-8719
-
-
Parente, R.A.1
Nadasdi, L.2
Subbarao, N.K.3
Szoka Jr., F.C.4
-
87
-
-
0027655718
-
Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
-
Haensler J, Szoka FC Jr: Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjug Chem (1993) 4:372-379.
-
(1993)
Bioconjug Chem
, vol.4
, pp. 372-379
-
-
Haensler, J.1
Szoka Jr., F.C.2
-
88
-
-
0028199067
-
The influence of endosome-destructive peptides on gene transfer using synthetic virus-like gene transfer systems
-
Plank C, Oberhauser B, Mechtler K, Koch C, Wagner E: The influence of endosome-destructive peptides on gene transfer using synthetic virus-like gene transfer systems. J Biol Chem (1994) 269:12918-12924.
-
(1994)
J Biol Chem
, vol.269
, pp. 12918-12924
-
-
Plank, C.1
Oberhauser, B.2
Mechtler, K.3
Koch, C.4
Wagner, E.5
-
89
-
-
0032032440
-
Membrane permeabilization and efficient gene transfer by a peptide containing several histidines
-
Midoux P, Kichler A, Boutin V, Maurizot J-C, Monsigny M: Membrane permeabilization and efficient gene transfer by a peptide containing several histidines. Bioconjug Chem (1998) 9:260-267. Demonstration of efficient gene transfer by histidine-containing peptides.
-
(1998)
Bioconjug Chem
, vol.9
, pp. 260-267
-
-
Midoux, P.1
Kichler, A.2
Boutin, V.3
Maurizot, J.-C.4
Monsigny, M.5
-
90
-
-
0030458784
-
Efficacy of a peptide-based gene delivery system depends on mitotic activity
-
Wilke M, Fortunati E, van den Broek M, Hoogeveen AT, Scholte BJ: Efficacy of a peptide-based gene delivery system depends on mitotic activity. Gene Ther (1996) 3:1133-1142.
-
(1996)
Gene Ther
, vol.3
, pp. 1133-1142
-
-
Wilke, M.1
Fortunati, E.2
Van Den Broek, M.3
Hoogeveen, A.T.4
Scholte, B.J.5
-
91
-
-
0029056088
-
Cellular and molecular barriers to gene transfer by a cationic lipid
-
Zabner J, Fasbender AJ, Moninger T, Poellinger KA, Welsh MJ: Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem (1995) 270:18997-19007.
-
(1995)
J Biol Chem
, vol.270
, pp. 18997-19007
-
-
Zabner, J.1
Fasbender, A.J.2
Moninger, T.3
Poellinger, K.A.4
Welsh, M.J.5
-
92
-
-
0029949266
-
Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
-
Xu Y, Szoka Jr FC: Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry (1996) 35:5616-5623. Proposed DNA release from the lipid/plasmid complexes in cells by the action of cytoplasmic anionic lipids.
-
(1996)
Biochemistry
, vol.35
, pp. 5616-5623
-
-
Xu, Y.1
Szoka Jr., F.C.2
-
93
-
-
0029857893
-
An electron microscopy study into the mechanism of gene transfer with lipopolyamines
-
Labat Moleur F, Steffan AM, Brisson C, Perron H, Feugeas O, Furstenberger P, Oberling F, Brambilla E, Behr JP: An electron microscopy study into the mechanism of gene transfer with lipopolyamines. Gene Ther (1996) 3:1010-1017. Detailed information on the factors limiting nuclear entry of plasmids and gene expression.
-
(1996)
Gene Ther
, vol.3
, pp. 1010-1017
-
-
Labat Moleur, F.1
Steffan, A.M.2
Brisson, C.3
Perron, H.4
Feugeas, O.5
Furstenberger, P.6
Oberling, F.7
Brambilla, E.8
Behr, J.P.9
-
94
-
-
0032571392
-
Polyethyleneimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells
-
Pollard H, Remy JS, Loussouam G, Demolombe S, Behr JP, Escande D: Polyethyleneimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J Biol Chem (1998) 273:7507-7511.
-
(1998)
J Biol Chem
, vol.273
, pp. 7507-7511
-
-
Pollard, H.1
Remy, J.S.2
Loussouam, G.3
Demolombe, S.4
Behr, J.P.5
Escande, D.6
-
96
-
-
0030964105
-
Nucleocytoplasmic transport: Signals, mechanisms and regulation
-
Nigg EA: Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature (1997) 386:779-787. Comprehensive review on intracellular trafficking of proteins.
-
(1997)
Nature
, vol.386
, pp. 779-787
-
-
Nigg, E.A.1
-
97
-
-
0343352388
-
Nucleocytoplasmic trafficking: Implications for the nuclear import of plasmid DNA during gene therapy
-
Boulikas T: Nucleocytoplasmic trafficking: implications for the nuclear import of plasmid DNA during gene therapy. Gene Ther Mol Biol (1998) 1:713-740.
-
(1998)
Gene Ther Mol Biol
, vol.1
, pp. 713-740
-
-
Boulikas, T.1
-
98
-
-
0029797971
-
Regulation of protein transport to the nucleus: Central role of phosphorylation
-
Jans DA, Hübner S: Regulation of protein transport to the nucleus: central role of phosphorylation. Physiol Rev (1996) 76:651-685.
-
(1996)
Physiol Rev
, vol.76
, pp. 651-685
-
-
Jans, D.A.1
Hübner, S.2
-
99
-
-
0024386888
-
Nuclear location signal-mediated protein transport
-
Roberts B: Nuclear location signal-mediated protein transport. Biochim Biophys Acta (1989) 1008:263-280.
-
(1989)
Biochim Biophys Acta
, vol.1008
, pp. 263-280
-
-
Roberts, B.1
-
100
-
-
0021269089
-
Sequence requirements for nuclear location of simian virus 40 large-T antigen
-
Kalderon D, Richardson WD, Markham AF, Smith AE: Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature (1984) 311:33-38.
-
(1984)
Nature
, vol.311
, pp. 33-38
-
-
Kalderon, D.1
Richardson, W.D.2
Markham, A.F.3
Smith, A.E.4
-
101
-
-
1842330324
-
SV40 large tumor antigen nuclear import is regulated by the double-stranded DNA-dependent protein kinase site (serine 120) flanking the nuclear localization sequence
-
Xiao CY, Hübner S, Jans DA: SV40 large tumor antigen nuclear import is regulated by the double-stranded DNA-dependent protein kinase site (serine 120) flanking the nuclear localization sequence. J Biol Chem (1997) 272:22191-22198.
-
(1997)
J Biol Chem
, vol.272
, pp. 22191-22198
-
-
Xiao, C.Y.1
Hübner, S.2
Jans, D.A.3
-
102
-
-
0026806847
-
A long synthetic peptide containing a nuclear localization signal and its flanking sequences of SV40 T-antigen directs the transport of IgM into the nucleus efficiently
-
Yoneda Y, Semba T, Kaneda Y, Noble RL, Matsuoka Y, Kurihara T, Okada Y, Imamoto N: A long synthetic peptide containing a nuclear localization signal and its flanking sequences of SV40 T-antigen directs the transport of IgM into the nucleus efficiently. Exp Cell Res (1992) 201:313-320.
-
(1992)
Exp Cell Res
, vol.201
, pp. 313-320
-
-
Yoneda, Y.1
Semba, T.2
Kaneda, Y.3
Noble, R.L.4
Matsuoka, Y.5
Kurihara, T.6
Okada, Y.7
Imamoto, N.8
-
103
-
-
0022460644
-
Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal
-
Lanford RE, Kanda P, Kennedy RC: Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal. Cell (1986) 46:575-582.
-
(1986)
Cell
, vol.46
, pp. 575-582
-
-
Lanford, R.E.1
Kanda, P.2
Kennedy, R.C.3
-
104
-
-
0021670868
-
Construction and characterization of an SV40 mutant defective in nuclear transport of T-antigen
-
Lanford RE, Butel JS: Construction and characterization of an SV40 mutant defective in nuclear transport of T-antigen. Cell (1984) 37:801-813.
-
(1984)
Cell
, vol.37
, pp. 801-813
-
-
Lanford, R.E.1
Butel, J.S.2
-
105
-
-
0030298522
-
The nuclear localization sequence of the SV40 T antigen promotes transgene uptake and expression in zebrafish embryo nuclei
-
Collas P, Husebye H, Aleström P: The nuclear localization sequence of the SV40 T antigen promotes transgene uptake and expression in zebrafish embryo nuclei. Transgenic Res (1996) 5:451-458. Demonstrated of the significant enhancement in uptake and gene expression in zebrafish embryo by NLS peptide.
-
(1996)
Transgenic Res
, vol.5
, pp. 451-458
-
-
Collas, P.1
Husebye, H.2
Aleström, P.3
-
106
-
-
0029984570
-
Nucleocytoplasmic transport
-
Görlich D, Mattaj IW: Nucleocytoplasmic transport Science (1996) 271:1513-1518.
-
(1996)
Science
, vol.271
, pp. 1513-1518
-
-
Görlich, D.1
Mattaj, I.W.2
-
107
-
-
0021167363
-
Targeting of E coli β-galactosidase to the nucleus in yeast
-
Hall MN, Hereford L, Herskowitz I: Targeting of E coli β-galactosidase to the nucleus in yeast. Cell (1984) 36:1057-1065.
-
(1984)
Cell
, vol.36
, pp. 1057-1065
-
-
Hall, M.N.1
Hereford, L.2
Herskowitz, I.3
-
108
-
-
0023146679
-
The carboxyl 35 amino acids of SV40 Vp3 are essential for its nuclear accumulation
-
Gharakhanian E, Takahashi J, Kasamatsu H: The carboxyl 35 amino acids of SV40 Vp3 are essential for its nuclear accumulation. Virology (1987) 157:440-448.
-
(1987)
Virology
, vol.157
, pp. 440-448
-
-
Gharakhanian, E.1
Takahashi, J.2
Kasamatsu, H.3
-
109
-
-
0023376779
-
Pentapeptide nuclear localization signal in adenovirus E1A
-
Lyons RH, Ferguson BQ, Rosenberg M: Pentapeptide nuclear localization signal in adenovirus E1A. Mol Cell Biol (1987) 7:2451-2456.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 2451-2456
-
-
Lyons, R.H.1
Ferguson, B.Q.2
Rosenberg, M.3
-
110
-
-
0025021189
-
Characterization of nuclear localizing sequences derived from yeast ribosomal protein L29
-
Underwood MR, Fried HM: Characterization of nuclear localizing sequences derived from yeast ribosomal protein L29. EMBO J (1990) 9:91-99.
-
(1990)
EMBO J
, vol.9
, pp. 91-99
-
-
Underwood, M.R.1
Fried, H.M.2
-
111
-
-
0023443764
-
Amino acid sequences that determine the nuclear localization of yeast histone 2B
-
Moreland RB, Langevin GL, Singer RH, Garcea RL, Hereford LM: Amino acid sequences that determine the nuclear localization of yeast histone 2B. Mol Cell Biol (1987) 7:4048-4057.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 4048-4057
-
-
Moreland, R.B.1
Langevin, G.L.2
Singer, R.H.3
Garcea, R.L.4
Hereford, L.M.5
-
112
-
-
0025190644
-
HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence
-
Malim M, Tiley LS, McCam DF, Rusche JR, Hauber J, Cullen BR: HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence. Cell (1990) 60:675-683.
-
(1990)
Cell
, vol.60
, pp. 675-683
-
-
Malim, M.1
Tiley, L.S.2
McCam, D.F.3
Rusche, J.R.4
Hauber, J.5
Cullen, B.R.6
-
113
-
-
0024064963
-
Mutations in the nuclear lamin proteins resulting in their aberrant assembly in the cytoplasm
-
Loewinger L, McKeon F: Mutations in the nuclear lamin proteins resulting in their aberrant assembly in the cytoplasm. EMBO J (1988) 7:2301-2309.
-
(1988)
EMBO J
, vol.7
, pp. 2301-2309
-
-
Loewinger, L.1
McKeon, F.2
-
114
-
-
0023441954
-
Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor
-
Picard D, Yamamoto KR: Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor. EMBO J (1987) 6:3333-3340.
-
(1987)
EMBO J
, vol.6
, pp. 3333-3340
-
-
Picard, D.1
Yamamoto, K.R.2
-
115
-
-
0023731952
-
Identification of the human c-myc protein nuclear translocation signal
-
Dang CV, Lee WM: Identification of the human c-myc protein nuclear translocation signal. Mol Cell Biol (1988) 8:4048-4054.
-
(1988)
Mol Cell Biol
, vol.8
, pp. 4048-4054
-
-
Dang, C.V.1
Lee, W.M.2
-
116
-
-
0026078249
-
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
-
Bobbins J, Dilworth SM, Laskey RA, Dingwall C: Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell (1991) 64:615-623.
-
(1991)
Cell
, vol.64
, pp. 615-623
-
-
Bobbins, J.1
Dilworth, S.M.2
Laskey, R.A.3
Dingwall, C.4
-
117
-
-
0024022449
-
Identification of domains involved in nuclear uptake and histone binding of protein N1 of Xenopus laevis
-
Kleinschmidt JA, Seiter A: Identification of domains involved in nuclear uptake and histone binding of protein N1 of Xenopus laevis. EMBO J (1988) 7:1605-1614.
-
(1988)
EMBO J
, vol.7
, pp. 1605-1614
-
-
Kleinschmidt, J.A.1
Seiter, A.2
-
118
-
-
0028943643
-
Nuclear localization of the testis determining gene product SRY
-
Poulat F, Girard F, Chevran MP, Gozé C, Rebillard X, Calas B, Lamb N, Berta P: Nuclear localization of the testis determining gene product SRY. J Cell Biol (1995) 128:737-748.
-
(1995)
J Cell Biol
, vol.128
, pp. 737-748
-
-
Poulat, F.1
Girard, F.2
Chevran, M.P.3
Gozé, C.4
Rebillard, X.5
Calas, B.6
Lamb, N.7
Berta, P.8
-
119
-
-
0028017489
-
Competition between nuclear localization and secretory signals determines the subcellular fate of a single CUG-initiated form of FGF3
-
Kiefer P, Acland P, Pappin D, Peters G, Dickson C: Competition between nuclear localization and secretory signals determines the subcellular fate of a single CUG-initiated form of FGF3. EMBO J (1994) 13:4126-4136.
-
(1994)
EMBO J
, vol.13
, pp. 4126-4136
-
-
Kiefer, P.1
Acland, P.2
Pappin, D.3
Peters, G.4
Dickson, C.5
-
120
-
-
0026662651
-
The human poly(ADP-ribose)polymerase nuclear localization signal is a bipartite element functionally separate from DNA binding and catalytic activity
-
Schreiber A, Molinete M, Boeuf H, de Murcia G, Menissier-de Murcia J: The human poly(ADP-ribose)polymerase nuclear localization signal is a bipartite element functionally separate from DNA binding and catalytic activity. EMBO J (1992) 11:3263-3269.
-
(1992)
EMBO J
, vol.11
, pp. 3263-3269
-
-
Schreiber, A.1
Molinete, M.2
Boeuf, H.3
De Murcia, G.4
Menissier-de Murcia, J.5
-
121
-
-
0024597585
-
Increased expression of DNA cointroduced with nuclear protein in adult rat liver
-
Kaneda Y, Iwai K, Uchida T: Increased expression of DNA cointroduced with nuclear protein in adult rat liver. Science (1989) 243:375-378.
-
(1989)
Science
, vol.243
, pp. 375-378
-
-
Kaneda, Y.1
Iwai, K.2
Uchida, T.3
-
122
-
-
0029836074
-
Gene transfer into mammalian cells using histone-condensed plasmid DNA
-
Fritz JD, Herweijer H, Zhang G, Wolff JA: Gene transfer into mammalian cells using histone-condensed plasmid DNA. Hum Gene Ther (1996) 7:1395-1404.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1395-1404
-
-
Fritz, J.D.1
Herweijer, H.2
Zhang, G.3
Wolff, J.A.4
-
123
-
-
0030768810
-
Nuclear import of DNA in digitonin-permeabilized cells
-
Hagstrom JE, Ludtke JJ, Bassik MC, Sebestyén MG, Adam SA, Wolff JA: Nuclear import of DNA in digitonin-permeabilized cells. J Cell Sci (1997) 110:2323-2331.
-
(1997)
J Cell Sci
, vol.110
, pp. 2323-2331
-
-
Hagstrom, J.E.1
Ludtke, J.J.2
Bassik, M.C.3
Sebestyén, M.G.4
Adam, S.A.5
Wolff, J.A.6
-
124
-
-
0031106046
-
Rapid targeting of plasmid DNA to zebrafish embryo nuclei by the nuclear localization signal of SV40 T antigen
-
Collas P, Aleström P: Rapid targeting of plasmid DNA to zebrafish embryo nuclei by the nuclear localization signal of SV40 T antigen. Mol Mar Biol Biotechnol (1997) 6:48-58.
-
(1997)
Mol Mar Biol Biotechnol
, vol.6
, pp. 48-58
-
-
Collas, P.1
Aleström, P.2
-
125
-
-
0029843122
-
Cationic liposome/plasmid complexes: In vitro cell entry and transgene expression augmented by synthetic signal peptides
-
Conary JT, Erdos G, McGuine M, Faulks R, Price O, Christman B, Brigham K, Ebner F, Schreier H: Cationic liposome/plasmid complexes: In vitro cell entry and transgene expression augmented by synthetic signal peptides. Eur J Pharm Biopharm (1996) 42:277-285.
-
(1996)
Eur J Pharm Biopharm
, vol.42
, pp. 277-285
-
-
Conary, J.T.1
Erdos, G.2
McGuine, M.3
Faulks, R.4
Price, O.5
Christman, B.6
Brigham, K.7
Ebner, F.8
Schreier, H.9
-
126
-
-
0028939896
-
Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: A stage toward artificial viruses
-
Remy JS, Kichler A, Mordvinov V, Schuber F, Behr JP: Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses. Proc Natl Acad Sci USA (1995) 92:1744-1748.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1744-1748
-
-
Remy, J.S.1
Kichler, A.2
Mordvinov, V.3
Schuber, F.4
Behr, J.P.5
-
127
-
-
0031974554
-
DNA vector chemistry: The covalent attachment of signal peptides to plasmid DNA
-
Sebestyen MG, Ludtke JJ, Bassik MC, Zhang G, Budker V, Lukhtanov EA, Hagstrom JE, Wolff JA: DNA vector chemistry: The covalent attachment of signal peptides to plasmid DNA. War Biotechnol (1998) 16:80-85.
-
(1998)
War Biotechnol
, vol.16
, pp. 80-85
-
-
Sebestyen, M.G.1
Ludtke, J.J.2
Bassik, M.C.3
Zhang, G.4
Budker, V.5
Lukhtanov, E.A.6
Hagstrom, J.E.7
Wolff, J.A.8
-
128
-
-
0033524453
-
Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNa to the cell nucleus
-
Zanta MA, Belguise-Valladier P, Behr JP: Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci USA (1999) 96:91-96. Demonstration of the significant enhancement in transfection by a single NLS peptide linked to one end of the reporter gene.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 91-96
-
-
Zanta, M.A.1
Belguise-Valladier, P.2
Behr, J.P.3
-
129
-
-
0032539707
-
Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells
-
Faruqi AF, Egholm M, Glazer PM: Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells. Proc Natl Acad Sci USA (1998) 95:1398-1403.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1398-1403
-
-
Faruqi, A.F.1
Egholm, M.2
Glazer, P.M.3
-
130
-
-
15844404886
-
Target cell-specific DNA transfer mediated by a chimeric multidomain protein novel non-viral gene delivery system
-
Fominaya J, Wels W: Target cell-specific DNA transfer mediated by a chimeric multidomain protein novel non-viral gene delivery system. J Biol Chem (1996) 271:10560-10568.
-
(1996)
J Biol Chem
, vol.271
, pp. 10560-10568
-
-
Fominaya, J.1
Wels, W.2
-
131
-
-
0031719662
-
Mutual exclusivity of DNA binding and nuclear localization signal recognition by the yeast transcrption factor GAL4: Implications for non-viral DNA delivery
-
Chan CK, Hubner S, Hu W, Jans DA: Mutual exclusivity of DNA binding and nuclear localization signal recognition by the yeast transcrption factor GAL4: implications for non-viral DNA delivery. Gene Ther (1998) 5:1204-1212.
-
(1998)
Gene Ther
, vol.5
, pp. 1204-1212
-
-
Chan, C.K.1
Hubner, S.2
Hu, W.3
Jans, D.A.4
-
132
-
-
0030221192
-
Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids
-
Makkerh JPS, Dingwall C, Laskey RA: Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids. Curr Biol (1996) 6:1025-1027.
-
(1996)
Curr Biol
, vol.6
, pp. 1025-1027
-
-
Makkerh, J.P.S.1
Dingwall, C.2
Laskey, R.A.3
-
133
-
-
0027399966
-
Cyclic amphipathic peptide-DNA complexes mediate high efficiency transfection of adherent mammalian cells
-
Legendre JY, Szoka FC Jr: Cyclic amphipathic peptide-DNA complexes mediate high efficiency transfection of adherent mammalian cells. Proc Natl Acad Sci USA (1993) 90: 893-897.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 893-897
-
-
Legendre, J.Y.1
Szoka Jr., F.C.2
-
134
-
-
0030890748
-
Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers
-
Wyman TB, Nicol F, Zelphati O, Scaria PV, Plank C, Szoka FC Jr: Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry (1997) 36:3008-3017. Design of a cationic amphipathic peptide, KALA, which itself mediates plasmid delivery and transfection. The KALA sequence provides a starting point for a family of peptides that incorporate other functions to improve gene delivery systems.
-
(1997)
Biochemistry
, vol.36
, pp. 3008-3017
-
-
Wyman, T.B.1
Nicol, F.2
Zelphati, O.3
Scaria, P.V.4
Plank, C.5
Szoka Jr., F.C.6
-
135
-
-
0030881509
-
Gene transfer using a novel fusion protein, GAL4/invasin
-
Paul RW, Weisser KE, Loomis A, Sloane DL, LaFoe D, Atkinson EM, Overall RW: Gene transfer using a novel fusion protein, GAL4/invasin. Hum Gene Ther (1997) 8:1253-1262.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 1253-1262
-
-
Paul, R.W.1
Weisser, K.E.2
Loomis, A.3
Sloane, D.L.4
LaFoe, D.5
Atkinson, E.M.6
Overall, R.W.7
-
136
-
-
0032496287
-
Novel vectors for gene delivery formed by self-assembly of DNA with poly(L-lysine) grafted with hydrophilic polymers
-
Toncheva V, Wolfert MA, Dash PR, Oupicky D, Ulbrich K, Seymour LW, Schacht EH: Novel vectors for gene delivery formed by self-assembly of DNA with poly(L-lysine) grafted with hydrophilic polymers. Biochim Biophys Acta (1998) 1380:354-368.
-
(1998)
Biochim Biophys Acta
, vol.1380
, pp. 354-368
-
-
Toncheva, V.1
Wolfert, M.A.2
Dash, P.R.3
Oupicky, D.4
Ulbrich, K.5
Seymour, L.W.6
Schacht, E.H.7
-
137
-
-
0029395709
-
Application of the multiple antigenic peptides (MAP) strategy to the production of prohormone convertases antibodies: Synthesis, characterization and use of 8-branched immunogenic peptides
-
Basak A, Boudreault A, Chen A, Chretién M, Seidah NG, Lazure C: Application of the multiple antigenic peptides (MAP) strategy to the production of prohormone convertases antibodies: synthesis, characterization and use of 8-branched immunogenic peptides. J Pept Sci (1995) 1:385-395.
-
(1995)
J Pept Sci
, vol.1
, pp. 385-395
-
-
Basak, A.1
Boudreault, A.2
Chen, A.3
Chretién, M.4
Seidah, N.G.5
Lazure, C.6
-
138
-
-
0018428323
-
Encapsulation of high molecular weight DNA in large unilamellar phospholipid vesicles. Dependence on the size of the DNA
-
Mannino RJ, Allebach ES, Strohl WA: Encapsulation of high molecular weight DNA in large unilamellar phospholipid vesicles. Dependence on the size of the DNA. FEBS Lett (1979) 101:229-232.
-
(1979)
FEBS Lett
, vol.101
, pp. 229-232
-
-
Mannino, R.J.1
Allebach, E.S.2
Strohl, W.A.3
-
139
-
-
0031851486
-
Characterization of cationic lipid-protamine-DNA complexes for intravenous gene delivery
-
Li S, Rizzo MA, Bhattacharya S, Huang L Characterization of cationic lipid-protamine-DNA complexes for intravenous gene delivery. Gene Ther (1998) 5:930-937.
-
(1998)
Gene Ther
, vol.5
, pp. 930-937
-
-
Li, S.1
Rizzo, M.A.2
Bhattacharya, S.3
Huang, L.4
-
140
-
-
0030032075
-
Effects of fusogenic and DNA-binding amphiphilic compounds on the receptor-mediated gene transfer into hepatic cells by asialofetuin-labeled liposomes
-
Hara T, Kuwasawa H, Aramaki Y, Takada S, Koike K, Ishidate K, Kato H, Tsuchiya S: Effects of fusogenic and DNA-binding amphiphilic compounds on the receptor-mediated gene transfer into hepatic cells by asialofetuin-labeled liposomes. Biochim Biophys Acta (1996) 1278:51-56.
-
(1996)
Biochim Biophys Acta
, vol.1278
, pp. 51-56
-
-
Hara, T.1
Kuwasawa, H.2
Aramaki, Y.3
Takada, S.4
Koike, K.5
Ishidate, K.6
Kato, H.7
Tsuchiya, S.8
-
141
-
-
0031041965
-
Dioleoylmelitin as a novel serum-insensitive reagent for efficient transfection of mammalian cells
-
Legendre JY, Trzeciak A, Bohrmann B, Deuschle U, Kitas E, Supersaxo A: Dioleoylmelitin as a novel serum-insensitive reagent for efficient transfection of mammalian cells. Bioconjug Chem (1997) 8:57-63.
-
(1997)
Bioconjug Chem
, vol.8
, pp. 57-63
-
-
Legendre, J.Y.1
Trzeciak, A.2
Bohrmann, B.3
Deuschle, U.4
Kitas, E.5
Supersaxo, A.6
-
142
-
-
0029562430
-
Short-chain phospholipids enhance amphipathic peptide-mediated gene transfer
-
Legendre JY, Supersaxo A: Short-chain phospholipids enhance amphipathic peptide-mediated gene transfer. Biochem Biophys Res Commun (1995) 217:179-185.
-
(1995)
Biochem Biophys Res Commun
, vol.217
, pp. 179-185
-
-
Legendre, J.Y.1
Supersaxo, A.2
-
143
-
-
0031825183
-
Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusogenic peptides
-
Simöes S, Slepushkin V, Gasper R, Pedroso deLima MC, Düzgünes N: Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusogenic peptides. Gene Ther (1998) 5:955-964.
-
(1998)
Gene Ther
, vol.5
, pp. 955-964
-
-
Simöes, S.1
Slepushkin, V.2
Gasper, R.3
Pedroso DeLima, M.C.4
Düzgünes, N.5
-
144
-
-
0032902891
-
Preparation and characterization of poty(D,L-lactide-coglycolide) microspheres for controlled release of poly(L-lysine) complexed plasmid DNA
-
in press
-
Capan Y, Woo BH, Gebrekidan S, Ahmed S, DeLuca PP: Preparation and characterization of poty(D,L-lactide-coglycolide) microspheres for controlled release of poly(L-lysine) complexed plasmid DNA. Pharm Res (1999) in press.
-
(1999)
Pharm Res
-
-
Capan, Y.1
Woo, B.H.2
Gebrekidan, S.3
Ahmed, S.4
DeLuca, P.P.5
-
145
-
-
0031048568
-
Peptide-mediated gene delivery: Influence of peptide structure on gene expression
-
Wadhwa MS, Collard WT, Adami RC, McKenzie DL, Rice KG: Peptide-mediated gene delivery: influence of peptide structure on gene expression. Bioconj Chem (1997) 8:81-88.
-
(1997)
Bioconj Chem
, vol.8
, pp. 81-88
-
-
Wadhwa, M.S.1
Collard, W.T.2
Adami, R.C.3
McKenzie, D.L.4
Rice, K.G.5
|