-
1
-
-
0035839109
-
Argonaute2, a link between genetic and biochemical analyses of RNAi
-
Hammond SM et al. Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 2001; 293: 1146-1150.
-
(2001)
Science
, vol.293
, pp. 1146-1150
-
-
Hammond, S.M.1
-
2
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
Martinez J et al. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 2002; 110: 563-574.
-
(2002)
Cell
, vol.110
, pp. 563-574
-
-
Martinez, J.1
-
3
-
-
0037087780
-
miRNPs: A novel class of ribonucleoproteins containing numerous microRNAs
-
Mourelatos Z et al. miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev 2002; 16: 720-728.
-
(2002)
Genes Dev.
, vol.16
, pp. 720-728
-
-
Mourelatos, Z.1
-
4
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvagner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme complex. Science 2002; 297: 2056-2060.
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
-
5
-
-
0037425583
-
Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors
-
Doi N et al. Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors. Curr Biol 2003; 13: 41-46.
-
(2003)
Curr. Biol.
, vol.13
, pp. 41-46
-
-
Doi, N.1
-
6
-
-
0036792769
-
Fragile X-related protein and VIG associate with the RNA interference machinery
-
Caudy AA, Myers M, Hannon GJ, Hammond SM. Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev 2002; 16: 2491-2496.
-
(2002)
Genes Dev.
, vol.16
, pp. 2491-2496
-
-
Caudy, A.A.1
Myers, M.2
Hannon, G.J.3
Hammond, S.M.4
-
7
-
-
0036791671
-
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins
-
Ishizuka A, Siomi MC, Siomi H. A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev 2002; 16: 2497-2508.
-
(2002)
Genes Dev.
, vol.16
, pp. 2497-2508
-
-
Ishizuka, A.1
Siomi, M.C.2
Siomi, H.3
-
8
-
-
0036752955
-
Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways
-
Schwarz DS, Hutvagner G, Haley B, Zamore PD. Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol Cell 2002; 10: 537-548.
-
(2002)
Mol. Cell
, vol.10
, pp. 537-548
-
-
Schwarz, D.S.1
Hutvagner, G.2
Haley, B.3
Zamore, P.D.4
-
9
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz DS et al. Asymmetry in the assembly of the RNAi enzyme complex. Cell 2003; 115: 199-208.
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
-
10
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova A, Reynolds A, Jayasena SD. Functional siRNAs and miRNAs exhibit strand bias. Cell 2003; 115: 209-216.
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
11
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 2001; 409: 363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
12
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 2001; 15: 188-200.
-
(2001)
Genes Dev.
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
13
-
-
0034609759
-
Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos
-
Yang D, Lu H, Erickson JW. Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos. Curr Biol 2000; 10: 1191-1200.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1191-1200
-
-
Yang, D.1
Lu, H.2
Erickson, J.W.3
-
14
-
-
0141868916
-
R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
-
Liu Q et al. R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 2003; 301: 1921-1925.
-
(2003)
Science
, vol.301
, pp. 1921-1925
-
-
Liu, Q.1
-
15
-
-
0035803583
-
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
-
Elbashir SM et al. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J 2001; 20: 6877-6888.
-
(2001)
EMBO J.
, vol.20
, pp. 6877-6888
-
-
Elbashir, S.M.1
-
16
-
-
0141843655
-
A micrococcal nuclease homologue in RNAi effector complexes
-
Caudy AA et al. A micrococcal nuclease homologue in RNAi effector complexes. Nature 2003; 425: 411-414.
-
(2003)
Nature
, vol.425
, pp. 411-414
-
-
Caudy, A.A.1
-
17
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411: 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
-
18
-
-
0035859929
-
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
-
Caplen NJ et al. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc Natl Acad Sci USA 2001; 98: 9742-9747.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9742-9747
-
-
Caplen, N.J.1
-
19
-
-
0035807818
-
Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines
-
Billy E et al. Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines. Proc Natl Acad Sci USA 2001; 98: 14428-14433.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14428-14433
-
-
Billy, E.1
-
20
-
-
0035900651
-
On the role of RNA amplification in dsRNA-triggered gene silencing
-
Sijen T et al. On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 2001; 107: 465-476.
-
(2001)
Cell
, vol.107
, pp. 465-476
-
-
Sijen, T.1
-
21
-
-
0037192490
-
Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1
-
Winston WM, Molodowitch C, Hunter CP. Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science 2002; 295: 2456-2459.
-
(2002)
Science
, vol.295
, pp. 2456-2459
-
-
Winston, W.M.1
Molodowitch, C.2
Hunter, C.P.3
-
22
-
-
0141483742
-
Transport of dsRNA into cells by the transmembrane protein SID-1
-
Feinberg EH, Hunter CP. Transport of dsRNA into cells by the transmembrane protein SID-1. Science 2003; 301: 1545-1547.
-
(2003)
Science
, vol.301
, pp. 1545-1547
-
-
Feinberg, E.H.1
Hunter, C.P.2
-
23
-
-
0038738781
-
RNA interference is required for normal centromere function in fission yeast
-
Volpe T et al. RNA interference is required for normal centromere function in fission yeast. Chromosome Res 2003; 11: 137-146.
-
(2003)
Chromosome Res.
, vol.11
, pp. 137-146
-
-
Volpe, T.1
-
24
-
-
0037072660
-
Small RNAs correspond to centromere heterochromatic repeats
-
Reinhart BJ, Bartel DP. Small RNAs correspond to centromere heterochromatic repeats. Science 2002; 297: 1831.
-
(2002)
Science
, vol.297
, pp. 1831
-
-
Reinhart, B.J.1
Bartel, D.P.2
-
25
-
-
0037183856
-
Establishment and maintenance of a heterochromatin domain
-
Hall IM et al. Establishment and maintenance of a heterochromatin domain. Science 2002; 297: 2232-2237.
-
(2002)
Science
, vol.297
, pp. 2232-2237
-
-
Hall, I.M.1
-
26
-
-
0037422606
-
RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast
-
Hall IM, Noma K, Grewal SI. RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast. Proc Natl Acad Sci USA 2003; 100: 193-198.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 193-198
-
-
Hall, I.M.1
Noma, K.2
Grewal, S.I.3
-
27
-
-
0942279635
-
RNAi-mediated targeting of heterochromatin by the RITS complex
-
Verdel A et al. RNAi-mediated targeting of heterochromatin by the RITS complex. Science 2004; 303: 672-676.
-
(2004)
Science
, vol.303
, pp. 672-676
-
-
Verdel, A.1
-
28
-
-
0345306117
-
Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi
-
Sijen T, Plasterk RH. Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi. Nature 2003; 426: 310-314.
-
(2003)
Nature
, vol.426
, pp. 310-314
-
-
Sijen, T.1
Plasterk, R.H.2
-
29
-
-
4243085624
-
Distinct mechanisms determine transposon inheritance and methylation via small interfering RNA and histone modification
-
Lippman Z et al. Distinct mechanisms determine transposon inheritance and methylation via small interfering RNA and histone modification. PLoS Biol 2003; 1: E67.
-
(2003)
PLoS Biol.
, vol.1
-
-
Lippman, Z.1
-
30
-
-
0042831010
-
Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing
-
Schramke V, Allshire R. Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing. Science 2003; 301: 1069-1074.
-
(2003)
Science
, vol.301
, pp. 1069-1074
-
-
Schramke, V.1
Allshire, R.2
-
31
-
-
17844364875
-
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
-
Grishok A et al. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 2001; 106: 23-34.
-
(2001)
Cell
, vol.106
, pp. 23-34
-
-
Grishok, A.1
-
32
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner G et al. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 2001; 293: 834-838.
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
-
33
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting RF et al. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev 2001; 15: 2654-2659.
-
(2001)
Genes Dev.
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
-
34
-
-
0035929322
-
A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
-
Knight SW, Bass BL. A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 2001; 293: 2269-2271.
-
(2001)
Science
, vol.293
, pp. 2269-2271
-
-
Knight, S.W.1
Bass, B.L.2
-
35
-
-
0242266620
-
Dicer is essential for mouse development
-
Bernstein E et al. Dicer is essential for mouse development. Nat Genet 2003; 35: 215-217.
-
(2003)
Nat. Genet.
, vol.35
, pp. 215-217
-
-
Bernstein, E.1
-
37
-
-
0041691111
-
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
-
Zeng Y, Yi R, Cullen BR. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc Natl Acad Sci USA 2003; 100: 9779-9784.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 9779-9784
-
-
Zeng, Y.1
Yi, R.2
Cullen, B.R.3
-
38
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
Paddison PJ et al. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev 2002; 16: 948-958.
-
(2002)
Genes Dev.
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
-
39
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002; 296: 550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
41
-
-
0036726313
-
Stable suppression of tumorigenicity by virus-mediated RNA interference
-
Brummelkamp TR, Bernards R, Agami R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2002; 2: 243-247.
-
(2002)
Cancer Cell
, vol.2
, pp. 243-247
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
42
-
-
0141750434
-
Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening
-
Aza-Blanc P et al. Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening. Mol Cell 2003; 12: 627-637.
-
(2003)
Mol. Cell
, vol.12
, pp. 627-637
-
-
Aza-Blanc, P.1
-
43
-
-
0037343270
-
Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference
-
Williams NS et al. Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference. Clin Cancer Res 2003; 9: 931-946.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 931-946
-
-
Williams, N.S.1
-
44
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
-
Kamath RS et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 2003; 421: 231-237.
-
(2003)
Nature
, vol.421
, pp. 231-237
-
-
Kamath, R.S.1
-
45
-
-
0037470952
-
Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells
-
Lum L et al. Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science 2003; 299: 2039-2045.
-
(2003)
Science
, vol.299
, pp. 2039-2045
-
-
Lum, L.1
-
46
-
-
0242361514
-
A functional genomic analysis of cell morphology using RNA interference
-
Kiger A et al. A functional genomic analysis of cell morphology using RNA interference. J Biol 2003; 2: 27.
-
(2003)
J. Biol.
, vol.2
, pp. 27
-
-
Kiger, A.1
-
47
-
-
12144288006
-
A resource for large-scale RNA-interference-based screens in mammals
-
Paddison PJ et al. A resource for large-scale RNA-interference-based screens in mammals. Nature 2004; 428: 427-431.
-
(2004)
Nature
, vol.428
, pp. 427-431
-
-
Paddison, P.J.1
-
48
-
-
12144289681
-
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
-
Berns K et al. A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 2004; 428: 431-437.
-
(2004)
Nature
, vol.428
, pp. 431-437
-
-
Berns, K.1
-
49
-
-
10744230287
-
RNAi microarray analysis in cultured mammalian cells
-
Mousses S et al. RNAi microarray analysis in cultured mammalian cells. Genome Res 2003; 13: 2341-2347.
-
(2003)
Genome Res.
, vol.13
, pp. 2341-2347
-
-
Mousses, S.1
-
50
-
-
0142092529
-
High-throughput selection of effective RNAi probes for gene silencing
-
Kumar R, Conklin DS, Mittal V. High-throughput selection of effective RNAi probes for gene silencing. Genome Res 2003; 13: 2333-2340.
-
(2003)
Genome Res.
, vol.13
, pp. 2333-2340
-
-
Kumar, R.1
Conklin, D.S.2
Mittal, V.3
-
51
-
-
0037370309
-
An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
-
Hemann MT et al. An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nat Genet 2003; 33: 396-400.
-
(2003)
Nat. Genet.
, vol.33
, pp. 396-400
-
-
Hemann, M.T.1
-
52
-
-
0037021437
-
Small interfering RNA and gene silencing in transgenic mice and rats
-
Hasuwa H, Kaseda K, Einarsdottir T, Okabe M. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett 2002; 532: 227-230.
-
(2002)
FEBS Lett.
, vol.532
, pp. 227-230
-
-
Hasuwa, H.1
Kaseda, K.2
Einarsdottir, T.3
Okabe, M.4
-
53
-
-
0037452812
-
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
-
Tiscornia G, Singer O, Ikawa M, Verma IM. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc Natl Acad Sci USA 2003; 100: 1844-1848.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1844-1848
-
-
Tiscornia, G.1
Singer, O.2
Ikawa, M.3
Verma, I.M.4
-
54
-
-
0037312978
-
Germline transmission of RNAi in mice
-
Carmell MA et al. Germline transmission of RNAi in mice. Nat Struct Biol 2003; 10: 147.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 147
-
-
Carmell, M.A.1
-
55
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
Rubinson DA et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 2003; 33: 401-406.
-
(2003)
Nat. Genet.
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
-
56
-
-
0038708339
-
Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype
-
Kunath T et al. Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype. Nat Biotechnol 2003; 21: 559-561.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 559-561
-
-
Kunath, T.1
-
57
-
-
0346216853
-
Local gene knockdown in the brain using viral-mediated RNA interference
-
Hommel JD et al. Local gene knockdown in the brain using viral-mediated RNA interference. Nat Med 2003; 9: 1539-1544.
-
(2003)
Nat. Med.
, vol.9
, pp. 1539-1544
-
-
Hommel, J.D.1
-
58
-
-
0037195064
-
Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA
-
Calegari F et al. Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA. Proc Natl Acad Sci USA 2002; 99: 14236-14240.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 14236-14240
-
-
Calegari, F.1
-
59
-
-
0037162522
-
Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
-
Yang D et al. Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proc Natl Acad Sci USA 2002; 99: 9942-9947.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9942-9947
-
-
Yang, D.1
-
60
-
-
0037335550
-
Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing
-
Myers JW, Jones JT, Meyer T, Ferrell Jr JE. Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing. Nat Biotechnol 2003; 21: 324-328.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 324-328
-
-
Myers, J.W.1
Jones, J.T.2
Meyer, T.3
Ferrell Jr., J.E.4
-
61
-
-
0037327444
-
siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells
-
Kawasaki H, Suyama E, Iyo M, Taira K. siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells. Nucleic Acids Res 2003; 31: 981-987.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 981-987
-
-
Kawasaki, H.1
Suyama, E.2
Iyo, M.3
Taira, K.4
-
62
-
-
0842310832
-
Restriction enzyme-generated siRNA (REGS) vectors and libraries
-
Sen G, Wehrman TS, Myers JW, Blau HM. Restriction enzyme-generated siRNA (REGS) vectors and libraries. Nat Genet 2004; 36: 183-189.
-
(2004)
Nat. Genet.
, vol.36
, pp. 183-189
-
-
Sen, G.1
Wehrman, T.S.2
Myers, J.W.3
Blau, H.M.4
-
63
-
-
0842332405
-
Enzymatic production of RNAi libraries from cDNAs
-
Shirane D et al. Enzymatic production of RNAi libraries from cDNAs. Nat Genet 2004; 36: 190-196.
-
(2004)
Nat. Genet.
, vol.36
, pp. 190-196
-
-
Shirane, D.1
-
64
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds A et al. Rational siRNA design for RNA interference. Nat Biotechnol 2004; 22: 326-330.
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
-
65
-
-
1642346273
-
Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference
-
Ui-Tei K et al. Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference. Nucleic Acids Res 2004; 32: 936-948.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 936-948
-
-
Ui-Tei, K.1
-
66
-
-
0037804642
-
Whither RNAi?
-
Whither RNAi? Nat Cell Biol 2003; 5: 489-490.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 489-490
-
-
-
67
-
-
4243754537
-
Confirming specificity of RNAi in mammalian cells
-
Lassus P, Rodriguez J, Lazebnik Y. Confirming specificity of RNAi in mammalian cells. Sci STKE 2002; 147: PL13.
-
(2002)
Sci. STKE
, vol.147
-
-
Lassus, P.1
Rodriguez, J.2
Lazebnik, Y.3
-
68
-
-
0037470145
-
Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis
-
Vickers TA et al. Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis. J Biol Chem 2003; 278: 7108-7118.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7108-7118
-
-
Vickers, T.A.1
-
69
-
-
0037280401
-
RNA interference may be more potent than antisense RNA in human cancer cell lines
-
Aoki Y et al. RNA interference may be more potent than antisense RNA in human cancer cell lines. Clin Exp Pharmacol Physiol 2003; 30: 96-102.
-
(2003)
Clin. Exp. Pharmacol. Physiol.
, vol.30
, pp. 96-102
-
-
Aoki, Y.1
-
70
-
-
24144445346
-
Comparison of the suppressive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells
-
Miyagishi M, Hayashi M, Taira K. Comparison of the suppressive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells. Antisense Nucleic Acid Drug Dev 2003; 13: 1-7.
-
(2003)
Antisense Nucleic Acid Drug Dev.
, vol.13
, pp. 1-7
-
-
Miyagishi, M.1
Hayashi, M.2
Taira, K.3
-
71
-
-
0038137215
-
Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant rat P2X3 receptor
-
Hemmings-Mieszczak M et al. Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant rat P2X3 receptor. Nucleic Acids Res 2003; 31: 2117-2126.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2117-2126
-
-
Hemmings-Mieszczak, M.1
-
72
-
-
0042972933
-
Activation of the interferon system by short-interfering RNAs
-
Sledz CA et al. Activation of the interferon system by short-interfering RNAs. Nat Cell Biol 2003; 5: 834-839.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 834-839
-
-
Sledz, C.A.1
-
73
-
-
0038419800
-
Induction of an interferon response by RNAi vectors in mammalian cells
-
Bridge AJ et al. Induction of an interferon response by RNAi vectors in mammalian cells. Nat Genet 2003; 34: 263-264.
-
(2003)
Nat. Genet.
, vol.34
, pp. 263-264
-
-
Bridge, A.J.1
-
74
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson AL et al. Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol 2003; 21: 635-637.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
-
75
-
-
0038132996
-
Allele-specific silencing of dominant disease genes
-
Miller VM et al. Allele-specific silencing of dominant disease genes. Proc Natl Acad Sci USA 2003; 100: 7195-7200.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7195-7200
-
-
Miller, V.M.1
-
77
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
-
Lee NS et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol 2002; 20: 500-505.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 500-505
-
-
Lee, N.S.1
-
78
-
-
0036727416
-
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
-
Lewis DL et al. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat Genet 2002; 32: 107-108.
-
(2002)
Nat. Genet.
, vol.32
, pp. 107-108
-
-
Lewis, D.L.1
-
79
-
-
0037019339
-
RNA interference in adult mice
-
McCaffrey AP et al. RNA interference in adult mice. Nature 2002; 418: 38-39.
-
(2002)
Nature
, vol.418
, pp. 38-39
-
-
McCaffrey, A.P.1
-
80
-
-
0037348329
-
RNA interference targeting Fas protects mice from fulminant hepatitis
-
Song E et al. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med 2003; 9: 347-351.
-
(2003)
Nat. Med.
, vol.9
, pp. 347-351
-
-
Song, E.1
-
81
-
-
0038610713
-
Caspase 8 small interfering RNA prevents acute liver failure in mice
-
Zender L et al. Caspase 8 small interfering RNA prevents acute liver failure in mice. Proc Natl Acad Sci USA 2003.
-
(2003)
Proc. Natl. Acad. Sci. USA
-
-
Zender, L.1
-
82
-
-
0038095650
-
Fas siRNA reduces apoptotic cell death of allogeneic-transplanted hepatocytes in mouse spleen
-
Wang J et al. Fas siRNA reduces apoptotic cell death of allogeneic-transplanted hepatocytes in mouse spleen. Transplant Proc 2003; 35: 1594-1595.
-
(2003)
Transplant. Proc.
, vol.35
, pp. 1594-1595
-
-
Wang, J.1
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