Co-delivery of siRNA and paclitaxel into cancer cells by biodegradable cationic micelles based on PDMAEMA-PCL-PDMAEMA triblock copolymers

Biomaterials

Volumn 31, Issue 8, 2010, Pages 2408-2416

  Zhu, Caihong ^a   Jung, Sooyeon ^b   Luo, Sibin ^a   Meng, Fenghua ^a   Zhu, Xiulin ^a   Park, Tae Gwan ^b   Zhong, Zhiyuan ^a  

^a SOOCHOW UNIVERSITY   (China)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Drug delivery; Gene delivery; Micelles; Paclitaxel; siRNA

Indexed keywords

ANTICANCER DRUG; BIODEGRADABLE MICELLES; CANCER CELLS; CATIONIC MICELLES; CELLULAR UPTAKE; CONFOCAL LASER SCANNING MICROSCOPE; DIMETHYLAMINOETHYL METHACRYLATES; DRUG EFFICACY; GEL-RETARDATION ASSAY; GENE DELIVERY; GENE SILENCING; GFP EXPRESSION; MACRO-RAFT AGENT; MOLE RATIO; NANO-SIZED; NILE RED; PACLITAXEL; PDMAEMA; POSITIVE SURFACE CHARGE; REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER POLYMERIZATION; TRIBLOCK COPOLYMERS;

BLOCK COPOLYMERS; CELLS; COPOLYMERIZATION; DRUG DELIVERY; GENE TRANSFER; HYDROGELS; RNA; SOFTWARE ARCHITECTURE;

MICELLES;

GREEN FLUORESCENT PROTEIN; PACLITAXEL; POLY[2 (DIMETHYLAMINO)ETHYL METHACRYLATE]; POLYCAPROLACTONE; SMALL INTERFERING RNA; VASCULOTROPIN; WATER;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIODEGRADABILITY; CANCER CELL; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG EFFICACY; GENE SILENCING; HUMAN; HUMAN CELL; MICELLE; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURFACE CHARGE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CATIONS; CELL LINE, TUMOR; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GREEN FLUORESCENT PROTEINS; HUMANS; MATERIALS TESTING; METHACRYLATES; MICELLES; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NYLONS; PACLITAXEL; PARTICLE SIZE; RNA, SMALL INTERFERING; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 74849097084     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.11.077     Document Type: Article

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