Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles

Pharmaceutical Research

Volumn 27, Issue 12, 2010, Pages 2520-2527

  Nielsen, Ebbe J B ^a   Nielsen, Jan M ^b   Becker, Daniel ^c   Karlas, Alexander ^c   Prakash, Hridayesh ^c   Glud, Sys Z ^a   Merrison, Jonathan ^a   Besenbacher, Flemming ^a   Meyer, Thomas F ^c   Kjems, Jørgen ^a   Howard, Kenneth A ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

Aerosol; Chitosan; Nanoparticles; Pulmonary gene silencing; RNA interference; SiRNA

Indexed keywords

CHITOSAN; ENHANCED GREEN FLUORESCENT PROTEIN; NANOPARTICLE; SMALL INTERFERING RNA;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG FORMULATION; FLOW CYTOMETRY; GENE DELIVERY SYSTEM; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE;

AEROSOLS; ANIMALS; BASE SEQUENCE; CELL LINE; CHITOSAN; FLOW CYTOMETRY; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; GREEN FLUORESCENT PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RNA INTERFERENCE;

EID: 78651341419     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0255-y     Document Type: Article

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