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Volumn 12, Issue 1, 2013, Pages 445-458

Pharmacological lifespan extension of invertebrates

Author keywords

Aging; C. elegans; Chemical screening; Drosophila; Drug discovery; Lifespan

Indexed keywords

ACETIC ACID; ALPHA TOCOPHEROL; ALPHA TOCOTRIENOL; ANTIOXIDANT; BLUEBERRY EXTRACT; CATECHIN; CELECOXIB; CURCUMIN; DAPSONE; DEOXYGLUCOSE; ETHOSUXIMIDE; GALLIC ACID PROPYL ESTER; GINKGO BILOBA EXTRACT; LAMOTRIGINE; METFORMIN; METITEPINE; MIANSERIN; OXALOACETIC ACID; QUERCETIN; RAPAMYCIN; RESERPINE; RESVERATROL; SPERMIDINE; THIOCTIC ACID; THIOFLAVINE; TREHALOSE; TRIMETHADIONE; TROLOX C; UNINDEXED DRUG; VALPROIC ACID;

EID: 84875910045     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2012.06.006     Document Type: Review
Times cited : (61)

References (156)
  • 1
    • 64549135111 scopus 로고    scopus 로고
    • Epigallocatechin gallate from green tea (Camellia sinensis) increases lifespan and stress resistance in Caenorhabditis elegans
    • Abbas S., Wink M. Epigallocatechin gallate from green tea (Camellia sinensis) increases lifespan and stress resistance in Caenorhabditis elegans. Planta Medica 2009, 75:216-221.
    • (2009) Planta Medica , vol.75 , pp. 216-221
    • Abbas, S.1    Wink, M.2
  • 2
    • 77955983432 scopus 로고    scopus 로고
    • Epigallocatechin gallate inhibits beta amyloid oligomerization in Caenorhabditis elegans and affects the daf-2/insulin-like signaling pathway
    • Abbas S., Wink M. Epigallocatechin gallate inhibits beta amyloid oligomerization in Caenorhabditis elegans and affects the daf-2/insulin-like signaling pathway. Phytomedicine 2010, 17:902-909.
    • (2010) Phytomedicine , vol.17 , pp. 902-909
    • Abbas, S.1    Wink, M.2
  • 5
    • 84858340718 scopus 로고    scopus 로고
    • Pharmacological maintenance of protein homeostasis could postpone age-related disease
    • Alavez S., Lithgow G.J. Pharmacological maintenance of protein homeostasis could postpone age-related disease. Aging cell 2012, 11:187-191.
    • (2012) Aging cell , vol.11 , pp. 187-191
    • Alavez, S.1    Lithgow, G.J.2
  • 6
    • 79954571967 scopus 로고    scopus 로고
    • Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan
    • Alavez S., Vantipalli M.C., Zucker D.J., Klang I.M., Lithgow G.J. Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan. Nature 2011, 472:226-229.
    • (2011) Nature , vol.472 , pp. 226-229
    • Alavez, S.1    Vantipalli, M.C.2    Zucker, D.J.3    Klang, I.M.4    Lithgow, G.J.5
  • 8
    • 67349229369 scopus 로고    scopus 로고
    • Reserpine ameliorates Abeta toxicity in the Alzheimer's disease model in Caenorhabditis elegans
    • Arya U., Dwivedi H., Subramaniam J.R. Reserpine ameliorates Abeta toxicity in the Alzheimer's disease model in Caenorhabditis elegans. Experimental Gerontology 2009, 44:462-466.
    • (2009) Experimental Gerontology , vol.44 , pp. 462-466
    • Arya, U.1    Dwivedi, H.2    Subramaniam, J.R.3
  • 9
    • 73449087667 scopus 로고    scopus 로고
    • Lamotrigine extends lifespan but compromises health span in Drosophila melanogaster
    • Avanesian A., Khodayari B., Felgner J.S., Jafari M. Lamotrigine extends lifespan but compromises health span in Drosophila melanogaster. Biogerontology 2010, 11:45-52.
    • (2010) Biogerontology , vol.11 , pp. 45-52
    • Avanesian, A.1    Khodayari, B.2    Felgner, J.S.3    Jafari, M.4
  • 10
    • 18144391553 scopus 로고    scopus 로고
    • Estrogen, insulin, and dietary signals cooperatively regulate longevity signals to enhance resistance to oxidative stress in mice
    • Baba T., Shimizu T., Suzuki Y., Ogawara M., Isono K., Koseki H., Kurosawa H., Shirasawa T. Estrogen, insulin, and dietary signals cooperatively regulate longevity signals to enhance resistance to oxidative stress in mice. Journal of Biological Chemistry 2005, 280:16417-16426.
    • (2005) Journal of Biological Chemistry , vol.280 , pp. 16417-16426
    • Baba, T.1    Shimizu, T.2    Suzuki, Y.3    Ogawara, M.4    Isono, K.5    Koseki, H.6    Kurosawa, H.7    Shirasawa, T.8
  • 11
    • 44149091227 scopus 로고    scopus 로고
    • Cocoa confers life span extension in Drosophila melanogaster
    • Bahadorani S., Hilliker A.J. Cocoa confers life span extension in Drosophila melanogaster. Nutrition Research 2008, 28:377-382.
    • (2008) Nutrition Research , vol.28 , pp. 377-382
    • Bahadorani, S.1    Hilliker, A.J.2
  • 18
    • 34249891333 scopus 로고    scopus 로고
    • Two neurons mediate diet-restriction-induced longevity in C. elegans
    • Bishop N.A., Guarente L. Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature 2007, 447:545-549.
    • (2007) Nature , vol.447 , pp. 545-549
    • Bishop, N.A.1    Guarente, L.2
  • 20
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • Bluher M., Kahn B.B., Kahn C.R. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 2003, 299:572-574.
    • (2003) Science , vol.299 , pp. 572-574
    • Bluher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 22
    • 0031450129 scopus 로고    scopus 로고
    • N-acetylcysteine slows down ageing and increases the life span of Drosophila melanogaster
    • Brack C., Bechter-Thuring E., Labuhn M. N-acetylcysteine slows down ageing and increases the life span of Drosophila melanogaster. Cellular and Molecular Life Sciences 1997, 53:960-966.
    • (1997) Cellular and Molecular Life Sciences , vol.53 , pp. 960-966
    • Brack, C.1    Bechter-Thuring, E.2    Labuhn, M.3
  • 25
    • 33846206505 scopus 로고    scopus 로고
    • Beneficial effects of natural antioxidants EGCG and alpha-lipoic acid on life span and age-dependent behavioral declines in Caenorhabditis elegans
    • Brown M.K., Evans J.L., Luo Y. Beneficial effects of natural antioxidants EGCG and alpha-lipoic acid on life span and age-dependent behavioral declines in Caenorhabditis elegans. Pharmacology Biochemistry and Behavior 2006, 85:620-628.
    • (2006) Pharmacology Biochemistry and Behavior , vol.85 , pp. 620-628
    • Brown, M.K.1    Evans, J.L.2    Luo, Y.3
  • 27
    • 83755186160 scopus 로고    scopus 로고
    • Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegans
    • Cai W.J., Huang J.H., Zhang S.Q., Wu B., Kapahi P., Zhang X.M., Shen Z.Y. Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegans. PLoS One 2011, 6:e28835.
    • (2011) PLoS One , vol.6
    • Cai, W.J.1    Huang, J.H.2    Zhang, S.Q.3    Wu, B.4    Kapahi, P.5    Zhang, X.M.6    Shen, Z.Y.7
  • 29
    • 0037072807 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation
    • Carmichael J., Sugars K.L., Bao Y.P., Rubinsztein D.C. Glycogen synthase kinase-3beta inhibitors prevent cellular polyglutamine toxicity caused by the Huntington's disease mutation. Journal of Biological Chemistry 2002, 277:33791-33798.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 33791-33798
    • Carmichael, J.1    Sugars, K.L.2    Bao, Y.P.3    Rubinsztein, D.C.4
  • 32
    • 79955951363 scopus 로고    scopus 로고
    • Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity
    • Ching T.T., Chiang W.C., Chen C.S., Hsu A.L. Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity. Aging Cell 2011, 10:506-519.
    • (2011) Aging Cell , vol.10 , pp. 506-519
    • Ching, T.T.1    Chiang, W.C.2    Chen, C.S.3    Hsu, A.L.4
  • 35
  • 36
    • 55449123081 scopus 로고    scopus 로고
    • The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan
    • Collins J.J., Evason K., Pickett C.L., Schneider D.L., Kornfeld K. The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan. PLoS Genetics 2008, 4:e1000230.
    • (2008) PLoS Genetics , vol.4
    • Collins, J.J.1    Evason, K.2    Pickett, C.L.3    Schneider, D.L.4    Kornfeld, K.5
  • 40
    • 0035515923 scopus 로고    scopus 로고
    • Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans
    • Feng J., Bussiere F., Hekimi S. Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans. Developmental Cell 2001, 1:633-644.
    • (2001) Developmental Cell , vol.1 , pp. 633-644
    • Feng, J.1    Bussiere, F.2    Hekimi, S.3
  • 42
    • 0023831256 scopus 로고
    • A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility
    • Friedman D.B., Johnson T.E. A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. Genetics 1988, 118:75-86.
    • (1988) Genetics , vol.118 , pp. 75-86
    • Friedman, D.B.1    Johnson, T.E.2
  • 43
    • 0023678537 scopus 로고
    • Three mutants that extend both mean and maximum life span of the nematode, Caenorhabditis elegans, define the age-1 gene
    • Friedman D.B., Johnson T.E. Three mutants that extend both mean and maximum life span of the nematode, Caenorhabditis elegans, define the age-1 gene. Journal of Gerontology 1988, 43:B102-B109.
    • (1988) Journal of Gerontology , vol.43
    • Friedman, D.B.1    Johnson, T.E.2
  • 44
    • 32644475678 scopus 로고
    • The use of Drosophila melanogaster as a screening agent for longevity factors; pantothenic acid as a longevity factor in royal jelly
    • Gardner T.S. The use of Drosophila melanogaster as a screening agent for longevity factors; pantothenic acid as a longevity factor in royal jelly. Journal of Gerontology 1948, 3:1-8.
    • (1948) Journal of Gerontology , vol.3 , pp. 1-8
    • Gardner, T.S.1
  • 45
    • 32644469815 scopus 로고
    • The use of Drosophila melanogaster as a screening agent for longevity factors; the effects of biotin, pyridoxine, sodium yeast nucleate, and pantothenic acid on the life span of the fruit fly
    • Gardner T.S. The use of Drosophila melanogaster as a screening agent for longevity factors; the effects of biotin, pyridoxine, sodium yeast nucleate, and pantothenic acid on the life span of the fruit fly. Journal of Gerontology 1948, 3:9-13.
    • (1948) Journal of Gerontology , vol.3 , pp. 9-13
    • Gardner, T.S.1
  • 46
    • 0031685525 scopus 로고    scopus 로고
    • Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans
    • Gems D., Sutton A.J., Sundermeyer M.L., Albert P.S., King K.V., Edgley M.L., Larsen P.L., Riddle D.L. Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. Genetics 1998, 150:129-155.
    • (1998) Genetics , vol.150 , pp. 129-155
    • Gems, D.1    Sutton, A.J.2    Sundermeyer, M.L.3    Albert, P.S.4    King, K.V.5    Edgley, M.L.6    Larsen, P.L.7    Riddle, D.L.8
  • 47
    • 23844436700 scopus 로고    scopus 로고
    • In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans
    • Gerstbrein B., Stamatas G., Kollias N., Driscoll M. In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans. Aging Cell 2005, 4:127-137.
    • (2005) Aging Cell , vol.4 , pp. 127-137
    • Gerstbrein, B.1    Stamatas, G.2    Kollias, N.3    Driscoll, M.4
  • 49
    • 33644850056 scopus 로고    scopus 로고
    • Progressive disruption of cellular protein folding in models of polyglutamine diseases
    • Gidalevitz T., Ben-Zvi A., Ho K.H., Brignull H.R., Morimoto R.I. Progressive disruption of cellular protein folding in models of polyglutamine diseases. Science 2006, 311:1471-1474.
    • (2006) Science , vol.311 , pp. 1471-1474
    • Gidalevitz, T.1    Ben-Zvi, A.2    Ho, K.H.3    Brignull, H.R.4    Morimoto, R.I.5
  • 50
    • 62149129690 scopus 로고    scopus 로고
    • Destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicity
    • Gidalevitz T., Krupinski T., Garcia S., Morimoto R.I. Destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicity. PLoS Genetics 2009, 5:e1000399.
    • (2009) PLoS Genetics , vol.5
    • Gidalevitz, T.1    Krupinski, T.2    Garcia, S.3    Morimoto, R.I.4
  • 51
    • 70350676299 scopus 로고    scopus 로고
    • Deceptively simple but simply deceptive - Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects
    • Gruber J., Ng L.F., Poovathingal S.K., Halliwell B. Deceptively simple but simply deceptive - Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects. FEBS Letters 2009, 583:3377-3387.
    • (2009) FEBS Letters , vol.583 , pp. 3377-3387
    • Gruber, J.1    Ng, L.F.2    Poovathingal, S.K.3    Halliwell, B.4
  • 52
    • 34249750383 scopus 로고    scopus 로고
    • Evidence for a trade-off between survival and fitness caused by resveratrol treatment of Caenorhabditis elegans
    • Gruber J., Tang S.Y., Halliwell B. Evidence for a trade-off between survival and fitness caused by resveratrol treatment of Caenorhabditis elegans. Annals of the New York Academy of Sciences 2007, 1100:530-542.
    • (2007) Annals of the New York Academy of Sciences , vol.1100 , pp. 530-542
    • Gruber, J.1    Tang, S.Y.2    Halliwell, B.3
  • 53
    • 79956311279 scopus 로고    scopus 로고
    • The novel hydroxylamine derivative NG-094 suppresses polyglutamine protein toxicity in Caenorhabditis elegans
    • Haldimann P., Muriset M., Vigh L., Goloubinoff P. The novel hydroxylamine derivative NG-094 suppresses polyglutamine protein toxicity in Caenorhabditis elegans. Journal of Biological Chemistry 2011, 286:18784-18794.
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 18784-18794
    • Haldimann, P.1    Muriset, M.2    Vigh, L.3    Goloubinoff, P.4
  • 55
  • 56
    • 0023869938 scopus 로고
    • Effect of vitamin E on lifespan and reproduction in Caenorhabditis elegans
    • Harrington L.A., Harley C.B. Effect of vitamin E on lifespan and reproduction in Caenorhabditis elegans. Mechanisms of Ageing and Development 1988, 43:71-78.
    • (1988) Mechanisms of Ageing and Development , vol.43 , pp. 71-78
    • Harrington, L.A.1    Harley, C.B.2
  • 58
    • 0034994933 scopus 로고    scopus 로고
    • Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans
    • Hartman P.S., Ishii N., Kayser E.B., Morgan P.G., Sedensky M.M. Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans. Mechanisms of Ageing and Development 2001, 122:1187-1201.
    • (2001) Mechanisms of Ageing and Development , vol.122 , pp. 1187-1201
    • Hartman, P.S.1    Ishii, N.2    Kayser, E.B.3    Morgan, P.G.4    Sedensky, M.M.5
  • 59
    • 0035846604 scopus 로고    scopus 로고
    • Daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
    • Henderson S.T., Johnson T.E. daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Current Biology 2001, 11:1975-1980.
    • (2001) Current Biology , vol.11 , pp. 1975-1980
    • Henderson, S.T.1    Johnson, T.E.2
  • 63
    • 78049437929 scopus 로고    scopus 로고
    • Trehalose extends longevity in the nematode Caenorhabditis elegans
    • Honda Y., Tanaka M., Honda S. Trehalose extends longevity in the nematode Caenorhabditis elegans. Aging Cell 2010, 9:558-569.
    • (2010) Aging Cell , vol.9 , pp. 558-569
    • Honda, Y.1    Tanaka, M.2    Honda, S.3
  • 65
    • 0034646688 scopus 로고    scopus 로고
    • The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2
    • Hsu A.L., Ching T.T., Wang D.S., Song X., Rangnekar V.M., Chen C.S. The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2. The Journal of Biological Chemistry 2000, 275:11397-11403.
    • (2000) The Journal of Biological Chemistry , vol.275 , pp. 11397-11403
    • Hsu, A.L.1    Ching, T.T.2    Wang, D.S.3    Song, X.4    Rangnekar, V.M.5    Chen, C.S.6
  • 66
    • 0038701745 scopus 로고    scopus 로고
    • Regulation of aging and age-related disease by DAF-16 and heat-shock factor
    • Hsu A.L., Murphy C.T., Kenyon C. Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 2003, 300:1142-1145.
    • (2003) Science , vol.300 , pp. 1142-1145
    • Hsu, A.L.1    Murphy, C.T.2    Kenyon, C.3
  • 70
    • 0033556060 scopus 로고    scopus 로고
    • Geroprotector effectiveness of melatonin: investigation of lifespan of Drosophila melanogaster
    • Izmaylov D.M., Obukhova L.K. Geroprotector effectiveness of melatonin: investigation of lifespan of Drosophila melanogaster. Mechanisms of Ageing and Development 1999, 106:233-240.
    • (1999) Mechanisms of Ageing and Development , vol.106 , pp. 233-240
    • Izmaylov, D.M.1    Obukhova, L.K.2
  • 71
    • 77957743058 scopus 로고    scopus 로고
    • Drosophila melanogaster as a model system for the evaluation of anti-aging compounds
    • Jafari M. Drosophila melanogaster as a model system for the evaluation of anti-aging compounds. Fly (Austin) 2010, 4:1-5.
    • (2010) Fly (Austin) , vol.4 , pp. 1-5
    • Jafari, M.1
  • 78
    • 77950191067 scopus 로고    scopus 로고
    • Dietary restriction and aging, 2009
    • Katewa S.D., Kapahi P. Dietary restriction and aging, 2009. Aging Cell 2010, 9:105-112.
    • (2010) Aging Cell , vol.9 , pp. 105-112
    • Katewa, S.D.1    Kapahi, P.2
  • 79
    • 2942555103 scopus 로고    scopus 로고
    • Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans
    • Keaney M., Matthijssens F., Sharpe M., Vanfleteren J., Gems D. Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans. Free Radical Biology and Medicine 2004, 37:239-250.
    • (2004) Free Radical Biology and Medicine , vol.37 , pp. 239-250
    • Keaney, M.1    Matthijssens, F.2    Sharpe, M.3    Vanfleteren, J.4    Gems, D.5
  • 80
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • Kenyon C., Chang J., Gensch E., Rudner A., Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 1993, 366:461-464.
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 81
    • 79961210760 scopus 로고    scopus 로고
    • Lithium protects against oxidative stress-mediated cell death in alpha-synuclein-overexpressing in vitro and in vivo models of Parkinson's disease
    • Kim Y.H., Rane A., Lussier S., Andersen J.K. Lithium protects against oxidative stress-mediated cell death in alpha-synuclein-overexpressing in vitro and in vivo models of Parkinson's disease. Journal of Neuroscience Research 2011, 89:1666-1675.
    • (2011) Journal of Neuroscience Research , vol.89 , pp. 1666-1675
    • Kim, Y.H.1    Rane, A.2    Lussier, S.3    Andersen, J.K.4
  • 82
    • 0030813398 scopus 로고    scopus 로고
    • Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • Kimura K.D., Tissenbaum H.A., Liu Y., Ruvkun G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 1997, 277:942-946.
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 83
    • 0021056471 scopus 로고
    • A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results
    • Klass M.R. A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results. Mechanisms of Ageing and Development 1983, 22:279-286.
    • (1983) Mechanisms of Ageing and Development , vol.22 , pp. 279-286
    • Klass, M.R.1
  • 84
    • 33646857050 scopus 로고    scopus 로고
    • The nongenotoxic carcinogens naphthalene and para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans
    • Kokel D., Li Y., Qin J., Xue D. The nongenotoxic carcinogens naphthalene and para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans. Nature Chemical Biology 2006, 2:338-345.
    • (2006) Nature Chemical Biology , vol.2 , pp. 338-345
    • Kokel, D.1    Li, Y.2    Qin, J.3    Xue, D.4
  • 85
    • 33845465149 scopus 로고    scopus 로고
    • A class of benzenoid chemicals suppresses apoptosis in C. elegans
    • Kokel D., Xue D. A class of benzenoid chemicals suppresses apoptosis in C. elegans. Chembiochem 2006, 7:2010-2015.
    • (2006) Chembiochem , vol.7 , pp. 2010-2015
    • Kokel, D.1    Xue, D.2
  • 91
    • 78650036223 scopus 로고    scopus 로고
    • Curcumin extends life span, improves health span, and modulates the expression of age-associated aging genes in Drosophila melanogaster
    • Lee K.S., Lee B.S., Semnani S., Avanesian A., Um C.Y., Jeon H.J., Seong K.M., Yu K., Min K.J., Jafari M. Curcumin extends life span, improves health span, and modulates the expression of age-associated aging genes in Drosophila melanogaster. Rejuvenation Research 2010, 13:561-570.
    • (2010) Rejuvenation Research , vol.13 , pp. 561-570
    • Lee, K.S.1    Lee, B.S.2    Semnani, S.3    Avanesian, A.4    Um, C.Y.5    Jeon, H.J.6    Seong, K.M.7    Yu, K.8    Min, K.J.9    Jafari, M.10
  • 92
    • 0037228016 scopus 로고    scopus 로고
    • A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
    • Lee S.S., Lee R.Y., Fraser A.G., Kamath R.S., Ahringer J., Ruvkun G. A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nature Genetics 2003, 33:40-48.
    • (2003) Nature Genetics , vol.33 , pp. 40-48
    • Lee, S.S.1    Lee, R.Y.2    Fraser, A.G.3    Kamath, R.S.4    Ahringer, J.5    Ruvkun, G.6
  • 93
    • 34447502384 scopus 로고    scopus 로고
    • Green tea catechins upregulate superoxide dismutase and catalase in fruit flies
    • Li Y.M., Chan H.Y., Huang Y., Chen Z.Y. Green tea catechins upregulate superoxide dismutase and catalase in fruit flies. Molecular Nutrition and Food Research 2007, 51:546-554.
    • (2007) Molecular Nutrition and Food Research , vol.51 , pp. 546-554
    • Li, Y.M.1    Chan, H.Y.2    Huang, Y.3    Chen, Z.Y.4
  • 94
    • 76249097841 scopus 로고    scopus 로고
    • Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening
    • Liao C.Y., Rikke B.A., Johnson T.E., Diaz V., Nelson J.F. Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening. Aging Cell 2010, 9:92-95.
    • (2010) Aging Cell , vol.9 , pp. 92-95
    • Liao, C.Y.1    Rikke, B.A.2    Johnson, T.E.3    Diaz, V.4    Nelson, J.F.5
  • 95
    • 0034967720 scopus 로고    scopus 로고
    • Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
    • Lin K., Hsin H., Libina N., Kenyon C. Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nature Genetics 2001, 28:139-145.
    • (2001) Nature Genetics , vol.28 , pp. 139-145
    • Lin, K.1    Hsin, H.2    Libina, N.3    Kenyon, C.4
  • 96
    • 0034703217 scopus 로고    scopus 로고
    • Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
    • Lin S.J., Defossez P.A., Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 2000, 289:2126-2128.
    • (2000) Science , vol.289 , pp. 2126-2128
    • Lin, S.J.1    Defossez, P.A.2    Guarente, L.3
  • 97
    • 33644898819 scopus 로고    scopus 로고
    • Manganous ion supplementation accelerates wild type development, enhances stress resistance, and rescues the life span of a short-lived Caenorhabditis elegans mutant
    • Lin Y.T., Hoang H., Hsieh S.I., Rangel N., Foster A.L., Sampayo J.N., Lithgow G.J., Srinivasan C. Manganous ion supplementation accelerates wild type development, enhances stress resistance, and rescues the life span of a short-lived Caenorhabditis elegans mutant. Free Radical Biology and Medicine 2006, 40:1185-1193.
    • (2006) Free Radical Biology and Medicine , vol.40 , pp. 1185-1193
    • Lin, Y.T.1    Hoang, H.2    Hsieh, S.I.3    Rangel, N.4    Foster, A.L.5    Sampayo, J.N.6    Lithgow, G.J.7    Srinivasan, C.8
  • 101
    • 66149135641 scopus 로고    scopus 로고
    • Drosophila models of neurodegenerative diseases
    • Lu B., Vogel H. Drosophila models of neurodegenerative diseases. Annual Review of Pathology 2009, 4:315-342.
    • (2009) Annual Review of Pathology , vol.4 , pp. 315-342
    • Lu, B.1    Vogel, H.2
  • 104
    • 0035503501 scopus 로고    scopus 로고
    • Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics
    • Melov S., Doctrow S.R., Schneider J.A., Haberson J., Patel M., Coskun P.E., Huffman K., Wallace D.C., Malfroy B. Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics. Journal of Neuroscience 2001, 21:8348-8353.
    • (2001) Journal of Neuroscience , vol.21 , pp. 8348-8353
    • Melov, S.1    Doctrow, S.R.2    Schneider, J.A.3    Haberson, J.4    Patel, M.5    Coskun, P.E.6    Huffman, K.7    Wallace, D.C.8    Malfroy, B.9
  • 109
    • 34447632659 scopus 로고    scopus 로고
    • Serotonin receptors antagonistically modulate Caenorhabditis elegans longevity
    • Murakami H., Murakami S. Serotonin receptors antagonistically modulate Caenorhabditis elegans longevity. Aging Cell 2007, 6:483-488.
    • (2007) Aging Cell , vol.6 , pp. 483-488
    • Murakami, H.1    Murakami, S.2
  • 111
    • 31744438846 scopus 로고    scopus 로고
    • Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation
    • Oh S.W., Mukhopadhyay A., Dixit B.L., Raha T., Green M.R., Tissenbaum H.A. Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nature Genetics 2006, 38:251-257.
    • (2006) Nature Genetics , vol.38 , pp. 251-257
    • Oh, S.W.1    Mukhopadhyay, A.2    Dixit, B.L.3    Raha, T.4    Green, M.R.5    Tissenbaum, H.A.6
  • 112
    • 77649311383 scopus 로고    scopus 로고
    • Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
    • Onken B., Driscoll M. Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1. PLoS One 2010, 5:e8758.
    • (2010) PLoS One , vol.5
    • Onken, B.1    Driscoll, M.2
  • 113
    • 34249888736 scopus 로고    scopus 로고
    • PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
    • Panowski S.H., Wolff S., Aguilaniu H., Durieux J., Dillin A. PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature 2007, 447:550-555.
    • (2007) Nature , vol.447 , pp. 550-555
    • Panowski, S.H.1    Wolff, S.2    Aguilaniu, H.3    Durieux, J.4    Dillin, A.5
  • 116
  • 117
    • 36549006956 scopus 로고    scopus 로고
    • An antidepressant that extends lifespan in adult Caenorhabditis elegans
    • Petrascheck M., Ye X., Buck L.B. An antidepressant that extends lifespan in adult Caenorhabditis elegans. Nature 2007, 450:553-556.
    • (2007) Nature , vol.450 , pp. 553-556
    • Petrascheck, M.1    Ye, X.2    Buck, L.B.3
  • 118
    • 68649084475 scopus 로고    scopus 로고
    • A high-throughput screen for chemicals that increase the lifespan of Caenorhabditis elegans
    • Petrascheck M., Ye X., Buck L.B. A high-throughput screen for chemicals that increase the lifespan of Caenorhabditis elegans. Annals of the New York Academy of Sciences 2009, 1170:698-701.
    • (2009) Annals of the New York Academy of Sciences , vol.1170 , pp. 698-701
    • Petrascheck, M.1    Ye, X.2    Buck, L.B.3
  • 119
    • 67650650445 scopus 로고    scopus 로고
    • Quercetin mediated lifespan extension in Caenorhabditis elegans is modulated by age-1, daf-2, sek-1 and unc-43
    • Pietsch K., Saul N., Menzel R., Sturzenbaum S.R., Steinberg C.E. Quercetin mediated lifespan extension in Caenorhabditis elegans is modulated by age-1, daf-2, sek-1 and unc-43. Biogerontology 2009, 10:565-578.
    • (2009) Biogerontology , vol.10 , pp. 565-578
    • Pietsch, K.1    Saul, N.2    Menzel, R.3    Sturzenbaum, S.R.4    Steinberg, C.E.5
  • 120
    • 79955632661 scopus 로고    scopus 로고
    • The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation
    • Powolny A.A., Singh S.V., Melov S., Hubbard A., Fisher A.L. The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation. Experimental Gerontology 2011, 46:441-452.
    • (2011) Experimental Gerontology , vol.46 , pp. 441-452
    • Powolny, A.A.1    Singh, S.V.2    Melov, S.3    Hubbard, A.4    Fisher, A.L.5
  • 121
    • 35648947912 scopus 로고    scopus 로고
    • Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans
    • Rea S.L., Ventura N., Johnson T.E. Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans. PLoS Biology 2007, 5:e259.
    • (2007) PLoS Biology , vol.5
    • Rea, S.L.1    Ventura, N.2    Johnson, T.E.3
  • 125
    • 84856225429 scopus 로고    scopus 로고
    • Reserpine modulates neurotransmitter release to extend lifespan and alleviate age-dependent Abeta proteotoxicity in Caenorhabditis elegans
    • Saharia K., Arya U., Kumar R., Sahu R., Das C.K., Gupta K., Dwivedi H., Subramaniam J.R. Reserpine modulates neurotransmitter release to extend lifespan and alleviate age-dependent Abeta proteotoxicity in Caenorhabditis elegans. Experimental Gerontology 2012, 47:188-197.
    • (2012) Experimental Gerontology , vol.47 , pp. 188-197
    • Saharia, K.1    Arya, U.2    Kumar, R.3    Sahu, R.4    Das, C.K.5    Gupta, K.6    Dwivedi, H.7    Subramaniam, J.R.8
  • 127
    • 2442465387 scopus 로고    scopus 로고
    • Oxidative stress in Caenorhabditis elegans: protective effects of superoxide dismutase/catalase mimetics
    • Sampayo J.N., Olsen A., Lithgow G.J. Oxidative stress in Caenorhabditis elegans: protective effects of superoxide dismutase/catalase mimetics. Aging Cell 2003, 2:319-326.
    • (2003) Aging Cell , vol.2 , pp. 319-326
    • Sampayo, J.N.1    Olsen, A.2    Lithgow, G.J.3
  • 131
    • 79952225237 scopus 로고    scopus 로고
    • Ferulsinaic acid attenuation of advanced glycation end products extends the lifespan of Caenorhabditis elegans
    • Sayed A.A. Ferulsinaic acid attenuation of advanced glycation end products extends the lifespan of Caenorhabditis elegans. Journal of Pharmacy and Pharmacology 2011, 63:423-428.
    • (2011) Journal of Pharmacy and Pharmacology , vol.63 , pp. 423-428
    • Sayed, A.A.1
  • 133
    • 34748850786 scopus 로고    scopus 로고
    • Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
    • Schulz T.J., Zarse K., Voigt A., Urban N., Birringer M., Ristow M. Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metabolism 2007, 6:280-293.
    • (2007) Cell Metabolism , vol.6 , pp. 280-293
    • Schulz, T.J.1    Zarse, K.2    Voigt, A.3    Urban, N.4    Birringer, M.5    Ristow, M.6
  • 134
    • 0347987853 scopus 로고    scopus 로고
    • Folding proteins in fatal ways
    • Selkoe D.J. Folding proteins in fatal ways. Nature 2003, 426:900-904.
    • (2003) Nature , vol.426 , pp. 900-904
    • Selkoe, D.J.1
  • 137
  • 139
    • 0031243334 scopus 로고    scopus 로고
    • Supplemental melatonin increases clonal lifespan in the protozoan Paramecium tetraurelia
    • Thomas J.N., Smith-Sonneborn J. Supplemental melatonin increases clonal lifespan in the protozoan Paramecium tetraurelia. Journal of Pineal Research 1997, 23:123-130.
    • (1997) Journal of Pineal Research , vol.23 , pp. 123-130
    • Thomas, J.N.1    Smith-Sonneborn, J.2
  • 144
    • 0027197284 scopus 로고
    • Oxidative stress and ageing in Caenorhabditis elegans
    • Vanfleteren J.R. Oxidative stress and ageing in Caenorhabditis elegans. Biochemical Journal 1993, 292(Pt 2):605-608.
    • (1993) Biochemical Journal , vol.292 , Issue.PART 2 , pp. 605-608
    • Vanfleteren, J.R.1
  • 145
    • 0041507039 scopus 로고    scopus 로고
    • Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin-like signals
    • Walker G.A., Lithgow G.J. Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin-like signals. Aging Cell 2003, 2:131-139.
    • (2003) Aging Cell , vol.2 , pp. 131-139
    • Walker, G.A.1    Lithgow, G.J.2
  • 146
    • 74049134984 scopus 로고    scopus 로고
    • Oxaloacetate supplementation increases lifespan in Caenorhabditis elegans through an AMPK/FOXO-dependent pathway
    • Williams D.S., Cash A., Hamadani L., Diemer T. Oxaloacetate supplementation increases lifespan in Caenorhabditis elegans through an AMPK/FOXO-dependent pathway. Aging Cell 2009, 8:765-768.
    • (2009) Aging Cell , vol.8 , pp. 765-768
    • Williams, D.S.1    Cash, A.2    Hamadani, L.3    Diemer, T.4
  • 149
    • 33845613251 scopus 로고    scopus 로고
    • Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans
    • Wu Y., Wu Z., Butko P., Christen Y., Lambert M.P., Klein W.L., Link C.D., Luo Y. Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans. Journal of Neuroscience 2006, 26:13102-13113.
    • (2006) Journal of Neuroscience , vol.26 , pp. 13102-13113
    • Wu, Y.1    Wu, Z.2    Butko, P.3    Christen, Y.4    Lambert, M.P.5    Klein, W.L.6    Link, C.D.7    Luo, Y.8
  • 151
    • 58149178553 scopus 로고    scopus 로고
    • Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegans
    • Zarse K., Ristow M. Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegans. PLoS One 2008, 3:e4062.
    • (2008) PLoS One , vol.3
    • Zarse, K.1    Ristow, M.2
  • 154
    • 84055223516 scopus 로고    scopus 로고
    • Inhibition of polyglutamine-mediated proteotoxicity by Astragalus membranaceus polysaccharide through the DAF-16/FOXO transcription factor in Caenorhabditis elegans
    • Zhang H., Pan N., Xiong S., Zou S., Li H., Xiao L., Cao Z., Tunnacliffe A., Huang Z. Inhibition of polyglutamine-mediated proteotoxicity by Astragalus membranaceus polysaccharide through the DAF-16/FOXO transcription factor in Caenorhabditis elegans. Biochemical Journal 2012, 441:417-424.
    • (2012) Biochemical Journal , vol.441 , pp. 417-424
    • Zhang, H.1    Pan, N.2    Xiong, S.3    Zou, S.4    Li, H.5    Xiao, L.6    Cao, Z.7    Tunnacliffe, A.8    Huang, Z.9
  • 155
    • 3042562279 scopus 로고    scopus 로고
    • From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors
    • Zhu J., Huang J.W., Tseng P.H., Yang Y.T., Fowble J., Shiau C.W., Shaw Y.J., Kulp S.K., Chen C.S. From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors. Cancer Research 2004, 64:4309-4318.
    • (2004) Cancer Research , vol.64 , pp. 4309-4318
    • Zhu, J.1    Huang, J.W.2    Tseng, P.H.3    Yang, Y.T.4    Fowble, J.5    Shiau, C.W.6    Shaw, Y.J.7    Kulp, S.K.8    Chen, C.S.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.