Drosophila melanogaster as a model system for the evaluation of anti-aging compounds

Fly

Volumn 4, Issue 3, 2010, Pages 253-257

  Jafari, Mahtab ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; Anti aging; Drosophila melanogaster

Indexed keywords

DROSOPHILA MELANOGASTER;

EID: 77957743058     PISSN: 19336934     EISSN: 19336942     Source Type: Journal    
DOI: 10.4161/fly.4.3.11997     Document Type: Article

References (47)

1. Carey JR, Liedo P, Orozco D, Vaupel JW. Slowing of mortality rates at older ages in large medfly cohorts. Science 1992; 258:457-461.
2. Vaupel JW, Carey JR, Christensen K, Johnson TE, Yashin AI, Holm NV et al. Biodemographic trajectories of longevity. Science 1998; 280:855-860.
3. Curtsinger JW, Fukui HH, Townsend DR, Vaupel JW. Demography of genotypes: failure of the limited life-span paradigm in Drosophila melanogaster. Science 1992; 258:461-463.
4. Rauser CL, Mueller LD, Rose MR. Aging, fertility and immortality. Exp Gerontol 2003; 38:27-33.
5. Bauer JH, Goupil S, Garber GB, Helfand SL. An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster. Proc Natl Acad Sci USA 2004; 101:12980-12985.
6. Mueller LD, Nusbaum TJ, Rose MR. The Gompertz equation as a predictive tool in demography. Exp Gerontol 1995; 30:553-569.
7. Finch CE. Longevity, Senescence, and the Genome Chicago: University of Chicago Press, 1990.
8. Joshi A, Shiotsugu J, Mueller LD. Phenotypic enhancement of longevity by environmental urea in Drosophila melanogaster. Exp Gerontol 1996; 31:533-544.
9. Jafari M, Rose MR. Rules for the use of model organisms in anti-aging pharmacology. Aging Cell 2006; 5:17-22.
10. Guarente L, Kenyon C. Genetic pathways that regulate ageing in model organisms. Nature 2000; 408:255-262.
11. Arking R. Biology of Aging: Observations and Principles. Sunderland, MA: Sinauer Associates, 1998.
12. Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 1993; 366:461-464.
13. Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G. Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 1997; 277:942-946.
14. Rogina B, Reenan RA, Nilsen SP, Helfand SL. Extended life-span conferred by cotransporter gene mutations in Drosophila. Science 2000; 290:2137-2140.
15. Broughton SJ, Piper MD, Ikeya T, Bass TM, Jacobson J, Driege Y et al. Longer lifespan, altered metabolism and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proc Natl Acad Sci USA 2005; 102:3105-3110.
16. Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, Hafen E et al. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 2001; 292:104-106.
17. Shen J, Curtis C, Tavare S, Tower J. A screen of apoptosis and senescence regulatory genes for life span effects when overexpressed in Drosophila. Aging (Albany NY) 2009; 1:191-211.
18. Rogina B, Helfand SL. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc Natl Acad Sci USA 2004; 101:15998-16003.
19. Rogina B, Helfand SL, Frankel S. Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction. Science 2002; 298:1745.
20. Tatar M, Kopelman A, Epstein D, Tu MP, Yin CM, Garofalo RS. A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. Science 2001; 292:107-110.
21. Pletcher SD, Macdonald SJ, Marguerie R, Certa U, Stearns SC, Goldstein DB et al. Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster. Curr Biol 2002; 12:712-723.
22. Rose MR, Long AD. Ageing: the many-headed monster. Curr Biol 2002; 12:311-312.
23. Fleming JE, Spicer GS, Garrison RC, Rose MR. Twodimensional protein electrophoretic analysis of postponed aging in Drosophila. Genetica 1993; 91:183-198.
24. Paaby AB, Schmidt PS. Dissecting the genetics of longevity in Drosophila melanogaster. Fly 2009; 3:29-38.
25. Toivonen JM, Gems D, Partridge L. Longevity of Indy mutant Drosophila not attributable to Indy mutation. Proc Natl Acad Sci USA 2009; 106:53.
26. Toivonen JM, Walker GA, Martinez-Diaz P, Bjedov I, Driege Y, Jacobs HT et al. No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects. PLoS Genet 2007; 3:95.
27. Baldal EA, Baktawar W, Brakefield PM, Zwaan BJ. Methuselah life history in a variety of conditions, implications for the use of mutants in longevity research. Exp Gerontol 2006; 41:1126-1135.
28. Lin SJ, Defossez PA, Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 2000; 289:2126-2128.
29. Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M et al. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 2004; 430:686-689.
30. Pacholec M, Bleasdale JE, Chrunyk B, Cunningham D, Flynn D, Garofalo RS et al. SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1. J Biol Chem; 285:8340-8351.
31. Rose MR, Passananti HB, Matos M. Methuselah Flies: A Case Study in the Evoultion of Aging. New Jersey: World Scientific Publications, 2004.
32. Miquel J, Lundgren PR, Bensch KG, Atlan H. Effects of temperature on the life span, vitality and fine structure of Drosophila melanogaster. Mech Ageing Dev 1976; 5:347-370.
33. Jafari M, Felgner JS, Bussel II, Hutchili T, Khodayari B, Rose MR et al. Rhodiola: a promising anti-aging Chinese herb. Rejuvenation Res 2007; 10:587-602.
34. Schriner SE, Abrahamyan A, Avanessian A, Bussel I, Maler S, Gazarian M et al. Decreased mitochondrial superoxide levels and enhanced protection against paraquat in Drosophila melanogaster supplemented with Rhodiola rosea. Free Radic Res 2009; 43:836-843.
35. Zou S, Sinclair J, Wilson MA, Carey JR, Liedo P, Oropeza A et al. Comparative approaches to facilitate the discovery of prolongevity interventions: effects of tocopherols on lifespan of three invertebrate species. Mech Ageing Dev 2007; 128:222-226.
36. Yu BP. Approaches to anti-aging intervention: the promises and the uncertainties. Mech Ageing Dev 1999; 111:73-87.
37. Avanesian A, Khodayari B, Felgner JS, Jafari M. Lamotrigine extends lifespan but compromises health span in Drosophila melanogaster. Biogerontology 2009.
38. Jafari M, Khodayari B, Felgner J, Bussel II, Rose MR, Mueller LD. Pioglitazone: an anti-diabetic compound with anti-aging properties. Biogerontology 2007; 8:639-651.
39. Kang HL, Benzer S, Min KT. Life extension in Drosophila by feeding a drug. Proc Natl Acad Sci USA 2002; 99:838-843.
40. Jafari M, Zarban A, Pham S, Wang T. Rosa damascene decreased mortality in adult Drosophila. J Med Food 2008; 11:9-13.
41. Rose MDMCASP. The morphology of postponed senescence in Drosophila melanogaster. Can J Zool 1984; 62:1576-1580.
42. Leroi AM CA, Rose MR. Long-term laboratory evolution of a genetic trade-off in Drosophila melanogaster I. Evolution 1994; 48.
43. Chapman T, Partridge L. Female fitness in Drosophila melanogaster: an interaction between the effect of nutrition and of encounter rate with males. Proc Biol Sci 1996; 263:755-759.
44. Chippindale AL, Kim SB, Rose MR. Metabolic aspects of the trade-off between fecundity and longevity in Drosophila melanogaster. Journal of Evolutionary Biology 1993; 10:269-293.
45. Van Voorhies WA, Curtsinger JW, Rose MR. Do longevity mutants always show trade-offs? Exp Gerontol 2006; 41:1055-1058.
46. Van Voorhies WA, Melvin RG, Ballard JW, Williams JB. Validation of manometric microrespirometers for measuring oxygen consumption in small arthropods. J Insect Physiol 2008; 54:1132-1137.
47. Feyereisen R. Insect P450 enzymes. Annu Rev Entomol 1999; 44:507-533.