The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan

PLoS Genetics

Volumn 4, Issue 10, 2008, Pages

  Collins, James J ^a   Evason, Kimberley ^a   Pickett, Christopher L ^a   Schneider, Daniel L ^a   Kornfeld, Kerry ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL T TYPE; ETHOSUXIMIDE; SEROTONIN; ANTICONVULSIVE AGENT; CAENORHABDITIS ELEGANS PROTEIN; CHE 3 PROTEIN, C ELEGANS; CHE-3 PROTEIN, C ELEGANS; DYNEIN ADENOSINE TRIPHOSPHATASE; KINESIN; OSM 3 PROTEIN, C ELEGANS; OSM-3 PROTEIN, C ELEGANS; UNCLASSIFIED DRUG;

ANTICONVULSANT ACTIVITY; ARTICLE; CAENORHABDITIS ELEGANS; CELL STRUCTURE; CHE 3 GENE; CHEMOSENSITIVITY; CHEMOTAXIS; CONTROLLED STUDY; DRUG ACTIVITY; EGG LAYING; GENE; GENE MUTATION; GENETIC ANALYSIS; LIFESPAN; NERVE CELL; NONHUMAN; OSM 3 GENE; PERCEPTIVE THRESHOLD; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; AGING; AMINO ACID SEQUENCE; ANIMAL; DRUG EFFECT; GENETICS; HUMAN; LONGEVITY; METABOLISM; MOLECULAR GENETICS; MUTATION; PHYSIOLOGY; SENSORY RECEPTOR;

ANIMALIA; CAENORHABDITIS ELEGANS;

AGING; AMINO ACID SEQUENCE; ANIMALS; ANTICONVULSANTS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CHEMOTAXIS; DYNEIN ATPASE; ETHOSUXIMIDE; HUMANS; KINESIN; LONGEVITY; MOLECULAR SEQUENCE DATA; MUTATION; SENSORY RECEPTOR CELLS;

EID: 55449123081     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000230     Document Type: Article

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