The novel hydroxylamine derivative NG-094 suppresses polyglutamine protein toxicity in Caenorhabditis elegans

Journal of Biological Chemistry

Volumn 286, Issue 21, 2011, Pages 18784-18794

  Haldimann, Pierre ^a   Muriset, Maude ^a   Vígh, László ^b   Goloubinoff, Pierre ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ADVERSE EFFECT; ANIMAL TISSUE; BODY WALL MUSCLES; CAENORHABDITIS ELEGANS; CELLULAR STRESS RESPONSE; CONFORMATIONAL DISEASE; CYTOPROTECTION; GROWTH FACTOR; HEAT-SHOCK; HEAT-SHOCK PROTEIN; HUNTINGTON DISEASE; HYDROXYLAMINE DERIVATIVE; MARGINAL EFFECTS; MICROMOLAR CONCENTRATION; MODEL SYSTEM; NEURODEGENERATIVE DISORDERS; NEW STRATEGY; POLYGLUTAMINE (POLYQ); POLYGLUTAMINE PROTEINS; PROTEOTOXICITY; YELLOW FLUORESCENT PROTEINS;

AMINES; AMINO ACIDS; MAMMALS; TISSUE; TRANSCRIPTION FACTORS;

NEURODEGENERATIVE DISEASES;

HEAT SHOCK TRANSCRIPTION FACTOR 1; HYDROXYLAMINE; NG 094; POLYGLUTAMINE; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN;

ANIMAL TISSUE; ARTICLE; BODY MOVEMENT; CAENORHABDITIS ELEGANS; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG EFFICACY; MUSCLE CELL; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DRUG EVALUATION, PRECLINICAL; HUMANS; HYDROXYLAMINES; INSULIN-LIKE GROWTH FACTOR I; MUSCLE PROTEINS; NEURODEGENERATIVE DISEASES; PEPTIDES; TRANSCRIPTION FACTORS;

ANIMALIA; CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 79956311279     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.234773     Document Type: Article

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