Chemical chaperones mediate increased secretion of mutant α1-antitrypsin (α1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in α1-AT deficiency

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 4, 2000, Pages 1796-1801

  Burrows, Jon A J ^a   Willis, Lauren K ^a   Perlmutter, David H ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

4 PHENYLBUTYRIC ACID; ALPHA 1 ANTITRYPSIN; ARYLBUTYRIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ALPHA 1 ANTITRYPSIN DEFICIENCY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; ENZYME RELEASE; LIVER INJURY; LUNG EMPHYSEMA; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ALPHA 1-ANTITRYPSIN; ALPHA 1-ANTITRYPSIN DEFICIENCY; ANIMALS; CELL LINE; EMPHYSEMA; GLYCEROL; HUMANS; LIVER; LUNG; METHYLAMINES; MICE; MICE, TRANSGENIC; MUTATION; PHENYLBUTYRATES; PROTEIN FOLDING; TEMPERATURE;

ANIMALIA;

EID: 0034652248     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.4.1796     Document Type: Article

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