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Volumn 32, Issue 1, 2013, Pages 4-18

Host defense at the ocular surface

Author keywords

Bacteria; Cornea; Epithelial cells; Pseudomonas aeruginosa; Toll like receptors

Indexed keywords

INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 1BETA; LIPOPEPTIDE; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN MD 2; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 11; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 9;

EID: 84873306100     PISSN: 08830185     EISSN: 15635244     Source Type: Journal    
DOI: 10.3109/08830185.2012.749400     Document Type: Review
Times cited : (91)

References (114)
  • 1
    • 84873297440 scopus 로고    scopus 로고
    • www.who.int/blindness/Vision2020 report.pdf.
  • 3
    • 69249119399 scopus 로고    scopus 로고
    • Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis
    • Turner JD, Langley RS, Johnston KL, et al. Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis. J Biol Chem 2009;284:22364-22378.
    • (2009) J Biol Chem , vol.284 , pp. 22364-22378
    • Turner, J.D.1    Langley, R.S.2    Johnston, K.L.3
  • 4
    • 79960131845 scopus 로고    scopus 로고
    • Onchocerciasis: The role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment
    • Tamarozzi F, Halliday A, Gentil K, et al. Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment. Clin Microbiol Rev 2011;24:459-468.
    • (2011) Clin Microbiol Rev , vol.24 , pp. 459-468
    • Tamarozzi, F.1    Halliday, A.2    Gentil, K.3
  • 5
    • 53749095611 scopus 로고    scopus 로고
    • Noncytotoxic lytic granule-mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latency
    • Knickelbein JE, Khanna KM, YeeMB, et al. Noncytotoxic lytic granule-mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latency. Science 2008;322:268-271.
    • (2008) Science , vol.322 , pp. 268-271
    • Knickelbein, J.E.1    Khanna, K.M.2    Yee, M.B.3
  • 6
    • 84873418782 scopus 로고    scopus 로고
    • Pathogenesis of herpes stromal keratitis - A focus on corneal neovascularization
    • Epub ahead of print]
    • Gimenez F, Suryawanshi A, Rouse BT. Pathogenesis of herpes stromal keratitis - a focus on corneal neovascularization. Prog Retin Eye Res 2012 [Epub ahead of print].
    • (2012) Prog Retin Eye Res
    • Gimenez, F.1    Suryawanshi, A.2    Rouse, B.T.3
  • 7
    • 79953214921 scopus 로고    scopus 로고
    • Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor
    • Suryawanshi A,Mulik S, Sharma S, et al. Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor. J Immunol 2011;186:3653-3665.
    • (2011) J Immunol , vol.186 , pp. 3653-3665
    • Suryawanshi, A.1    Mulik, S.2    Sharma, S.3
  • 8
    • 80052220145 scopus 로고    scopus 로고
    • Expression of innate and adaptive immunemediators in human corneal tissue infected with Aspergillus or fusarium
    • Karthikeyan RS, Leal SM, Jr., Prajna NV, et al. Expression of innate and adaptive immunemediators in human corneal tissue infected with Aspergillus or fusarium. J Infect Dis 2011;204:942-950.
    • (2011) J Infect Dis , vol.204 , pp. 942-950
    • Karthikeyan, R.S.1    Leal Jr., S.M.2    Prajna, N.V.3
  • 9
    • 77957675910 scopus 로고    scopus 로고
    • Distinct roles for Dectin-1 and TLR4 in the pathogenesis of Aspergillus fumigatus keratitis
    • Leal SM, Jr., Cowden S, Hsia YC, et al. Distinct roles for Dectin-1 and TLR4 in the pathogenesis of Aspergillus fumigatus keratitis. PLoS Pathog 2010;6:e1000976.
    • (2010) PLoS Pathog , vol.6
    • Leal Jr., S.M.1    Cowden, S.2    Hsia, Y.C.3
  • 10
    • 33744828507 scopus 로고    scopus 로고
    • The immunobiology of Acanthamoeba keratitis
    • DOI 10.1016/j.micinf.2005.12.009, PII S1286457906000190
    • Clarke DW, Niederkorn JY. The immunobiology of Acanthamoeba keratitis. Microbes Infect 2006;8:1400-1405. (Pubitemid 43831694)
    • (2006) Microbes and Infection , vol.8 , Issue.5 , pp. 1400-1405
    • Clarke, D.W.1    Niederkorn, J.Y.2
  • 11
    • 77049097374 scopus 로고    scopus 로고
    • Detection of bacterial endosymbionts in clinical Acanthamoeba isolates
    • Iovieno A, Ledee DR,Miller D, Alfonso EC. Detection of bacterial endosymbionts in clinical Acanthamoeba isolates. Ophthalmology 2010;117:445-452.
    • (2010) Ophthalmology , vol.117 , pp. 445-452
    • Iovieno, A.1    Ledee, D.R.2    Miller, D.3    Alfonso, E.C.4
  • 13
    • 84857457168 scopus 로고    scopus 로고
    • The role of cytokines and pathogen recognition molecules in fungal keratitis - Insights from human disease and animal models
    • Leal SM, Jr., Pearlman E. The role of cytokines and pathogen recognition molecules in fungal keratitis - insights from human disease and animal models. Cytokine 2012;58:107-111.
    • (2012) Cytokine , vol.58 , pp. 107-111
    • Leal Jr., S.M.1    Pearlman, E.2
  • 14
    • 0842346487 scopus 로고    scopus 로고
    • Corneal response to Pseudomonas aeruginosa infection
    • DOI 10.1016/j.preteyeres.2003.10.002
    • Hazlett LD. Corneal response to Pseudomonas aeruginosa infection. Prog Retin Eye Res 2004;23:1-30. (Pubitemid 38177170)
    • (2004) Progress in Retinal and Eye Research , vol.23 , Issue.1 , pp. 1-30
    • Hazlett, L.D.1
  • 15
    • 84949115394 scopus 로고    scopus 로고
    • Inflammatory response to Pseudomonas aeruginosa keratitis
    • Hazlett LD. Inflammatory response to Pseudomonas aeruginosa keratitis. Ocul Surf 2005;3:S139-S141.
    • (2005) Ocul Surf , vol.3
    • Hazlett, L.D.1
  • 16
    • 77954880812 scopus 로고    scopus 로고
    • Reviews for immune privilege in the year 2010: Immune privilege and infection
    • Hazlett LD, Hendricks RL. Reviews for immune privilege in the year 2010: immune privilege and infection. Ocul Immunol Inflamm 2010;18:237-243.
    • (2010) Ocul Immunol Inflamm , vol.18 , pp. 237-243
    • Hazlett, L.D.1    Hendricks, R.L.2
  • 17
    • 77956200581 scopus 로고    scopus 로고
    • Antimicrobial peptides as a major part of the innate immune defense at the ocular surface
    • Garreis F, Gottschalt M, Paulsen FP. Antimicrobial peptides as a major part of the innate immune defense at the ocular surface. Dev Ophthalmol 2012;45:16-22.
    • (2012) Dev Ophthalmol , vol.45 , pp. 16-22
    • Garreis, F.1    Gottschalt, M.2    Paulsen, F.P.3
  • 18
    • 80051755601 scopus 로고    scopus 로고
    • Tear lipocalin: Structure and function
    • Dartt DA. Tear lipocalin: structure and function. Ocul Surf 2011;9:126-138.
    • (2011) Ocul Surf , vol.9 , pp. 126-138
    • Dartt, D.A.1
  • 19
    • 58149131710 scopus 로고    scopus 로고
    • Role of lactoferrin in the tear film
    • Flanagan JL,Willcox MD. Role of lactoferrin in the tear film. Biochimie 2009;91:35-43.
    • (2009) Biochimie , vol.91 , pp. 35-43
    • Flanagan, J.L.1    Willcox, M.D.2
  • 20
    • 77952788856 scopus 로고    scopus 로고
    • Membrane-tetheredmucins havemultiple functions on the ocular surface
    • Govindarajan B, Gipson IK.Membrane-tetheredmucins havemultiple functions on the ocular surface. Exp Eye Res 2011;90:655-663.
    • (2011) Exp Eye Res , vol.90 , pp. 655-663
    • Govindarajan, B.1    Gipson, I.K.2
  • 21
    • 58149103363 scopus 로고    scopus 로고
    • The role of antimicrobial peptides at the ocular surface
    • McDermott AM. The role of antimicrobial peptides at the ocular surface. Ophthalmic Res 2009;41:60-75.
    • (2009) Ophthalmic Res , vol.41 , pp. 60-75
    • McDermott, A.M.1
  • 22
    • 79251524878 scopus 로고    scopus 로고
    • Role of defensins in corneal epithelial barrier function against Pseudomonas aeruginosa traversal
    • Augustin DK,Heimer SR,TamC, et al. Role of defensins in corneal epithelial barrier function against Pseudomonas aeruginosa traversal. Infect Immun 2011;79:595-605.
    • (2011) Infect Immun , vol.79 , pp. 595-605
    • Augustin, D.K.1    Heimer, S.R.2    Tam, C.3
  • 23
    • 76249084929 scopus 로고    scopus 로고
    • Beta-defensins 2 and 3 together promote resistance to Pseudomonas aeruginosa keratitis
    • Wu M,McClellan SA, Barrett RP, et al. Beta-defensins 2 and 3 together promote resistance to Pseudomonas aeruginosa keratitis. J Immunol 2009;183:8054-8060.
    • (2009) J Immunol , vol.183 , pp. 8054-8060
    • Wu, M.1    McClellan, S.A.2    Barrett, R.P.3
  • 24
    • 84867186262 scopus 로고    scopus 로고
    • Cytokeratins mediate epithelial innate defense through their antimicrobial properties
    • TamC,Mun JJ, Evans DJ, Fleiszig SM. Cytokeratins mediate epithelial innate defense through their antimicrobial properties. J Clin Invest 2012;122:3665-3677.
    • (2012) J Clin Invest , vol.122 , pp. 3665-3677
    • Tam, C.1    Mun, J.J.2    Evans, D.J.3    Fleiszig, S.M.4
  • 25
    • 53049084858 scopus 로고    scopus 로고
    • Toll-like receptors at the ocular surface
    • Pearlman E, Johnson A, Adhikary G, et al. Toll-like receptors at the ocular surface. Ocul Surf 2008;6:108-116.
    • (2008) Ocul Surf , vol.6 , pp. 108-116
    • Pearlman, E.1    Johnson, A.2    Adhikary, G.3
  • 26
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
    • Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2011;11:373-384.
    • (2011) Nat Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 27
    • 81055129630 scopus 로고    scopus 로고
    • CD14 controls the LPS-induced endocytosis of Toll-like receptor 4
    • Zanoni I, Ostuni R,Marek LR, et al. CD14 controls the LPS-induced endocytosis of Toll-like receptor 4. Cell 2011;147:868-880.
    • (2011) Cell , vol.147 , pp. 868-880
    • Zanoni, I.1    Ostuni, R.2    Marek, L.R.3
  • 33
    • 67349182481 scopus 로고    scopus 로고
    • The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
    • Park BS, Song DH, Kim HM, et al. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 2009;458:1191-1195.
    • (2009) Nature , vol.458 , pp. 1191-1195
    • Park, B.S.1    Song, D.H.2    Kim, H.M.3
  • 36
    • 44449108230 scopus 로고    scopus 로고
    • Cutting edge: Membrane nanotubes in vivo: A feature of MHC class II+ cells in the mouse cornea
    • Chinnery HR, Pearlman E,McMenamin PG. Cutting edge: membrane nanotubes in vivo: a feature of MHC class II+ cells in the mouse cornea. J Immunol 2008;180:5779-5783.
    • (2008) J Immunol , vol.180 , pp. 5779-5783
    • Chinnery, H.R.1    Pearlman, E.2    McMenamin, P.G.3
  • 38
    • 33947503696 scopus 로고    scopus 로고
    • Corneal antigen-presenting cells
    • DOI 10.1159/000099254, Immune Response and the Eye
    • Hamrah P, Dana MR. Corneal antigen-presenting cells. Chem Immunol Allergy 2007;92:58-70. (Pubitemid 47102939)
    • (2007) Chemical Immunology and Allergy , vol.92 , pp. 58-70
    • Hamrah, P.1    Dana, M.R.2
  • 39
    • 0041349296 scopus 로고    scopus 로고
    • Corneal immunity is mediated by heterogeneous population of antigen-presenting cells
    • DOI 10.1189/jlb.1102544
    • Hamrah P, Huq SO, Liu Y, et al. Corneal immunity is mediated by heterogeneous population of antigen-presenting cells. J Leukoc Biol 2003;74:172-178. (Pubitemid 38040413)
    • (2003) Journal of Leukocyte Biology , vol.74 , Issue.2 , pp. 172-178
    • Hamrah, P.1    Huq, S.O.2    Liu, Y.3    Zhang, Q.4    Dana, M.R.5
  • 40
    • 77958141017 scopus 로고    scopus 로고
    • TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways
    • Sun Y, Karmakar M, Roy S, et al. TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways. J Immunol 2010;185:4272-4283.
    • (2010) J Immunol , vol.185 , pp. 4272-4283
    • Sun, Y.1    Karmakar, M.2    Roy, S.3
  • 42
    • 0038560947 scopus 로고    scopus 로고
    • Macrophages restrict Pseudomonas aeruginosa growth, regulate polymorphonuclear neutrophil influx, and balance pro- and anti-inflammatory cytokines in BALB/c mice
    • McClellan SA, Huang X, Barrett RP, et al. Macrophages restrict Pseudomonas aeruginosa growth, regulate polymorphonuclear neutrophil influx, and balance pro- and anti-inflammatory cytokines in BALB/c mice. J Immunol 2003;170:5219-5227. (Pubitemid 36554755)
    • (2003) Journal of Immunology , vol.170 , Issue.10 , pp. 5219-5227
    • McClellan, S.A.1    Huang, X.2    Barrett, R.P.3    Van Rooijen, N.4    Hazlett, L.D.5
  • 43
    • 84863558332 scopus 로고    scopus 로고
    • Fungal antioxidant pathways promote survival against neutrophils during infection
    • Leal SM, Jr., Vareechon C, Cowden S, et al. Fungal antioxidant pathways promote survival against neutrophils during infection. J Clin Invest 2012;122:2482-2498.
    • (2012) J Clin Invest , vol.122 , pp. 2482-2498
    • Leal Jr., S.M.1    Vareechon, C.2    Cowden, S.3
  • 44
    • 33344468233 scopus 로고    scopus 로고
    • Neutrophils and immunity: Challenges and opportunities
    • DOI 10.1038/nri1785
    • Nathan C. Neutrophils and immunity: challenges and opportunities. Nat Rev Immunol 2006;6:173-182. (Pubitemid 43290987)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.3 , pp. 173-182
    • Nathan, C.1
  • 45
    • 77950682184 scopus 로고    scopus 로고
    • Theimpact of inoculation parameters on the pathogenesis of contact lens-related infectious keratitis
    • TamC,Mun JJ, Evans DJ, Fleiszig SM.Theimpact of inoculation parameters on the pathogenesis of contact lens-related infectious keratitis. Invest Ophthalmol Vis Sci 2010;51:3100-3106.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 3100-3106
    • Tam, C.1    Mun, J.J.2    Evans, D.J.3    Fleiszig, S.M.4
  • 46
    • 44449154463 scopus 로고    scopus 로고
    • 2 terminal kinase (JNK) is an essential mediator of toll-like receptor 2-induced corneal inflammation
    • DOI 10.1189/jlb.1107783
    • Adhikary G, Sun Y, Pearlman E. C-Jun NH2 terminal kinase (JNK) is an essential mediator of Tolllike receptor 2-induced corneal inflammation. J Leukoc Biol 2008;83:991-997. (Pubitemid 351959880)
    • (2008) Journal of Leukocyte Biology , vol.83 , Issue.4 , pp. 991-997
    • Adhikary, G.1    Sun, Y.2    Pearlman, E.3
  • 47
    • 32244445123 scopus 로고    scopus 로고
    • Toll-like receptor 2-mediated expression of β-defensin-2 in human corneal epithelial cells
    • DOI 10.1016/j.micinf.2005.07.006, PII S1286457905002728
    • Kumar A, Zhang J, Yu FS. Toll-like receptor 2-mediated expression of beta-defensin-2 in human corneal epithelial cells.Microbes Infect 2006;8:380-389. (Pubitemid 43214600)
    • (2006) Microbes and Infection , vol.8 , Issue.2 , pp. 380-389
    • Kumar, A.1    Zhang, J.2    Yu, F.-S.X.3
  • 48
    • 42949166405 scopus 로고    scopus 로고
    • MyD88 functions as a negative regulator of TLR3/TRIFinduced corneal inflammation by inhibiting activation of c-Jun N-terminal kinase
    • Johnson AC, Li X, Pearlman E. MyD88 functions as a negative regulator of TLR3/TRIFinduced corneal inflammation by inhibiting activation of c-Jun N-terminal kinase. J Biol Chem 2008;283:3988-3996.
    • (2008) J Biol Chem , vol.283 , pp. 3988-3996
    • Johnson, A.C.1    Li, X.2    Pearlman, E.3
  • 49
    • 17444368008 scopus 로고    scopus 로고
    • Triggering of TLR3 by polyI:C in human corneal epithelial cells to induce inflammatory cytokines
    • DOI 10.1016/j.bbrc.2005.02.196
    • Ueta M,Hamuro J, Kiyono H, Kinoshita S. Triggering of TLR3 by polyI:Cin human corneal epithelial cells to induce inflammatory cytokines. Biochem Biophys Res Commun 2005;331:285-294. (Pubitemid 40545174)
    • (2005) Biochemical and Biophysical Research Communications , vol.331 , Issue.1 , pp. 285-294
    • Ueta, M.1    Hamuro, J.2    Kiyono, H.3    Kinoshita, S.4
  • 50
    • 0141653750 scopus 로고    scopus 로고
    • Toll-like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin
    • DOI 10.1167/iovs.03-0219
    • Zhang J, Xu K, Ambati B, Yu FS. Toll-like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin. Invest Ophthalmol Vis Sci 2003;44:4247-4254. (Pubitemid 37186258)
    • (2003) Investigative Ophthalmology and Visual Science , vol.44 , Issue.10 , pp. 4247-4254
    • Zhang, J.1    Xu, K.2    Ambati, B.3    Yu, F.-S.X.4
  • 51
    • 83455179656 scopus 로고    scopus 로고
    • TLR9 ligand CpG-ODN applied to the injured mouse cornea elicits retinal inflammation
    • Chinnery HR, McLenachan S, Binz N, et al. TLR9 ligand CpG-ODN applied to the injured mouse cornea elicits retinal inflammation. AmJ Pathol 2012;180:209-220.
    • (2012) AmJ Pathol , vol.180 , pp. 209-220
    • Chinnery, H.R.1    McLenachan, S.2    Binz, N.3
  • 52
    • 62649164799 scopus 로고    scopus 로고
    • Inhibition of corneal inflammation by the TLR4 antagonist Eritoran tetrasodium (E5564)
    • Sun Y, Pearlman E. Inhibition of corneal inflammation by the TLR4 antagonist Eritoran tetrasodium (E5564). Invest Ophthalmol Vis Sci 2009;50:1247-1254.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 1247-1254
    • Sun, Y.1    Pearlman, E.2
  • 55
    • 60749121449 scopus 로고    scopus 로고
    • Lack of MD-2 expression in human corneal epithelial cells is an underlying mechanism of lipopolysaccharide (LPS) unresponsiveness
    • Zhang J, Kumar A, Wheater M, Yu FS. Lack of MD-2 expression in human corneal epithelial cells is an underlying mechanism of lipopolysaccharide (LPS) unresponsiveness. Immunol Cell Biol 2009;87:141-148.
    • (2009) Immunol Cell Biol , vol.87 , pp. 141-148
    • Zhang, J.1    Kumar, A.2    Wheater, M.3    Yu, F.S.4
  • 56
    • 79959901231 scopus 로고    scopus 로고
    • Interferon-gamma-induced MD-2 protein expression and lipopolysaccharide (LPS) responsiveness in corneal epithelial cells is mediated by Janus tyrosine kinase-2 activation and direct binding of STAT1 protein to the MD-2 promoter
    • Roy S, Sun Y, Pearlman E. Interferon-gamma-induced MD-2 protein expression and lipopolysaccharide (LPS) responsiveness in corneal epithelial cells is mediated by Janus tyrosine kinase-2 activation and direct binding of STAT1 protein to the MD-2 promoter. J Biol Chem 2011;286:23753-23762.
    • (2011) J Biol Chem , vol.286 , pp. 23753-23762
    • Roy, S.1    Sun, Y.2    Pearlman, E.3
  • 57
    • 34548760958 scopus 로고    scopus 로고
    • NKT cells are critical to initiate an inflammatory response after Pseudomonas aeruginosa ocular infection in susceptiblemice
    • Hazlett LD, Li Q, Liu J, et al. NKT cells are critical to initiate an inflammatory response after Pseudomonas aeruginosa ocular infection in susceptiblemice. J Immunol 2007;179:1138-1146.
    • (2007) J Immunol , vol.179 , pp. 1138-1146
    • Hazlett, L.D.1    Li, Q.2    Liu, J.3
  • 58
    • 35748965018 scopus 로고    scopus 로고
    • Modulation of corneal epithelial innate immune response to pseudomonas infection by flagellin pretreatment
    • DOI 10.1167/iovs.07-0473
    • Kumar A, Yin J, Zhang J, Yu FS.Modulation of corneal epithelial innate immune response to pseudomonas infection by flagellin pretreatment. Invest Ophthalmol Vis Sci 2007;48:4664-4670. (Pubitemid 351260984)
    • (2007) Investigative Ophthalmology and Visual Science , vol.48 , Issue.10 , pp. 4664-4670
    • Kumar, A.1    Yin, J.2    Zhang, J.3    Yu, F.-S.X.4
  • 59
    • 79952106615 scopus 로고    scopus 로고
    • Toll-like receptor activation modulates antimicrobial peptide expression by ocular surface cells
    • Redfern RL, Reins RY, McDermott AM. Toll-like receptor activation modulates antimicrobial peptide expression by ocular surface cells. Exp Eye Res 2011;92:209-220.
    • (2011) Exp Eye Res , vol.92 , pp. 209-220
    • Redfern, R.L.1    Reins, R.Y.2    McDermott, A.M.3
  • 60
    • 0034660146 scopus 로고    scopus 로고
    • Prolonged elevation of IL-1 in Pseudomonas aeruginosa ocular infection regulates macrophage-inflammatory protein-2 production, polymorphonuclear neutrophil persistence, and corneal perforation
    • Rudner XL, Kernacki KA, Barrett RP,Hazlett LD. Prolonged elevation of IL-1 in Pseudomonas aeruginosa ocular infection regulatesmacrophage-inflammatory protein-2 production, polymorphonuclear neutrophil persistence, and corneal perforation. J Immunol 2000;164:6576-6582. (Pubitemid 30408844)
    • (2000) Journal of Immunology , vol.164 , Issue.12 , pp. 6576-6582
    • Rudner, X.L.1    Kernacki, K.A.2    Barrett, R.P.3    Hazlett, L.D.4
  • 61
    • 84867903731 scopus 로고    scopus 로고
    • IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and Caspase-1
    • Karmakar M. Cutting Edge: IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and Caspase-1. Cutting Edge J Immunol 2012;189(9):4231- 4235.
    • (2012) Cutting Edge J Immunol , vol.189 , Issue.9 , pp. 4231-4235
    • Karmakar, M.1    Edge, C.2
  • 63
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J. The inflammasomes. Cell 2010;140:821-832.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 66
    • 77649241461 scopus 로고    scopus 로고
    • Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
    • Miao EA,Mao DP, Yudkovsky N, et al. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci USA 2010;107:3076-3080.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 3076-3080
    • Miao, E.A.1    Mao, D.P.2    Yudkovsky, N.3
  • 67
    • 84855296038 scopus 로고    scopus 로고
    • A novel role for the NLRC4 inflammasomeinmucosal defenses against the fungal pathogen Candida albicans
    • Tomalka J,Ganesan S, Azodi E, et al. A novel role for the NLRC4 inflammasomeinmucosal defenses against the fungal pathogen Candida albicans. PLoS Pathog 2011;7:e1002379.
    • (2011) PLoS Pathog , vol.7
    • Tomalka, J.1    Ganesan, S.2    Azodi, E.3
  • 69
    • 0023947763 scopus 로고
    • Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor
    • Black RA, Kronheim SR, Cantrell M, et al. Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor. J Biol Chem 1988;263:9437-9442.
    • (1988) J Biol Chem , vol.263 , pp. 9437-9442
    • Black, R.A.1    Kronheim, S.R.2    Cantrell, M.3
  • 70
    • 0025220123 scopus 로고
    • Processing of precursor interleukin 1 beta and inflammatory disease
    • Hazuda DJ, Strickler J, Kueppers F, et al. Processing of precursor interleukin 1 beta and inflammatory disease. J Biol Chem 1990;265:6318-6322.
    • (1990) J Biol Chem , vol.265 , pp. 6318-6322
    • Hazuda, D.J.1    Strickler, J.2    Kueppers, F.3
  • 71
    • 84859492693 scopus 로고    scopus 로고
    • The NLRP3/ASC/Caspase-1 axis regulates IL-1beta processing in neutrophils
    • Mankan AK, Dau T, Jenne D, Hornung V.The NLRP3/ASC/Caspase-1 axis regulates IL-1beta processing in neutrophils. Eur J Immunol 2011;42(3):710-715.
    • (2011) Eur J Immunol , vol.42 , Issue.3 , pp. 710-715
    • Mankan, A.K.1    Dau, T.2    Jenne, D.3    Hornung, V.4
  • 73
    • 11844299050 scopus 로고    scopus 로고
    • Regulation of Pseudomonas aeruginosa corneal infection in IL-1β converting enzyme (ICE, caspase-1) deficient mice
    • DOI 10.1080/02713680490516710
    • ThakurA,BarrettRP,McClellanS,HazlettLD.Regulationof Pseudomonasaeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice. Curr Eye Res 2004;29:225-233. (Pubitemid 40095005)
    • (2004) Current Eye Research , vol.29 , Issue.4-5 , pp. 225-233
    • Thakur, A.1    Barrett, R.P.2    McClellan, S.3    Hazlett, L.D.4
  • 75
    • 33745303252 scopus 로고    scopus 로고
    • SIGIRR promotes resistance against Pseudomonas aeruginosa keratitis by Down-regulating type-1 immunity and IL-1R1 and TLR4 signaling
    • Huang X, Hazlett LD, Du W, Barrett RP. SIGIRR promotes resistance against Pseudomonas aeruginosa keratitis by down-regulating type-1 immunity and IL-1R1 and TLR4 signaling. J Immunol 2006;177:548-556. (Pubitemid 43939168)
    • (2006) Journal of Immunology , vol.177 , Issue.1 , pp. 548-556
    • Huang, X.1    Hazlett, L.D.2    Du, W.3    Barrett, R.P.4
  • 76
    • 35748951316 scopus 로고    scopus 로고
    • ST2 is essential for Th2 responsiveness and resistance to Pseudomonas aeruginosa keratitis
    • DOI 10.1167/iovs.07-0316
    • Huang X, Du W, Barrett RP, Hazlett LD. ST2 is essential for Th2 responsiveness and resistance to Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci 2007;48:4626-4633. (Pubitemid 351260980)
    • (2007) Investigative Ophthalmology and Visual Science , vol.48 , Issue.10 , pp. 4626-4633
    • Huang, X.1    Du, W.2    Barrett, R.P.3    Hazlett, L.D.4
  • 78
    • 84862857096 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide downregulates proinflammatory TLRs while upregulating anti-inflammatory TLRs in the infected cornea
    • Jiang X, McClellan SA, Barrett RP, et al. Vasoactive intestinal peptide downregulates proinflammatory TLRs while upregulating anti-inflammatory TLRs in the infected cornea. J Immunol 2012;189:269-278.
    • (2012) J Immunol , vol.189 , pp. 269-278
    • Jiang, X.1    McClellan, S.A.2    Barrett, R.P.3
  • 79
    • 33847762256 scopus 로고    scopus 로고
    • Spantide I decreases type I cytokines, enhances IL-10, and reduces corneal perforation in susceptible mice after Pseudomonas aeruginosa infection
    • DOI 10.1167/iovs.06-0882
    • Hazlett LD, McClellan SA, Barrett RP, et al. Spantide I decreases type I cytokines, enhances IL-10, and reduces corneal perforation insusceptible mice after Pseudomonasaeruginosa infection. Invest Ophthalmol Vis Sci 2007;48:797-807. (Pubitemid 351260715)
    • (2007) Investigative Ophthalmology and Visual Science , vol.48 , Issue.2 , pp. 797-807
    • Hazlett, L.D.1    McClellan, S.A.2    Barrett, R.P.3    Liu, J.4    Zhang, Y.5    Lighvani, S.6
  • 80
    • 53449089161 scopus 로고    scopus 로고
    • Substance P delays apoptosis, enhancing keratitis after Pseudomonas aeruginosa infection
    • Zhou Z,BarrettRP,McClellan SA, et al. Substance P delays apoptosis, enhancing keratitis after Pseudomonas aeruginosa infection. Invest Ophthalmol Vis Sci 2008;49:4458-4467.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4458-4467
    • Zhou, Z.1    Barrett, R.P.2    McClellan, S.A.3
  • 82
    • 48549085489 scopus 로고    scopus 로고
    • Flagellin treatment protects against chemicals, bacteria, viruses, and radiation
    • Vijay-KumarM, Aitken JD, Sanders CJ, et al. Flagellin treatment protects against chemicals, bacteria, viruses, and radiation. J Immunol 2008;180:8280-8285.
    • (2008) J Immunol , vol.180 , pp. 8280-8285
    • Vijay-Kumar, M.1    Aitken, J.D.2    Sanders, C.J.3
  • 83
    • 77958105033 scopus 로고    scopus 로고
    • Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection
    • Kumar A, Gao N, Standiford TJ, et al. Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection.Microbes Infect 2010;12:978-989.
    • (2010) Microbes Infect , vol.12 , pp. 978-989
    • Kumar, A.1    Gao, N.2    Standiford, T.J.3
  • 84
    • 37749037714 scopus 로고    scopus 로고
    • Flagellin suppresses the inflammatory response and enhances bacterial clearance in a murine model of Pseudomonas aeruginosa keratitis
    • Kumar A, Hazlett LD, Yu FS. Flagellin suppresses the inflammatory response and enhances bacterial clearance in a murine model of Pseudomonas aeruginosa keratitis. Infect Immun 2008;76: 89-96.
    • (2008) Infect Immun , vol.76 , pp. 89-96
    • Kumar, A.1    Hazlett, L.D.2    Yu, F.S.3
  • 85
    • 77955494032 scopus 로고    scopus 로고
    • Flagellin stimulates protective lungmucosalimmunity: Role of cathelicidin-related antimicrobial peptide
    • Yu FS, Cornicelli MD, KovachMA, et al. Flagellin stimulates protective lungmucosalimmunity: role of cathelicidin-related antimicrobial peptide. J Immunol 2011;185:1142-1149.
    • (2011) J Immunol , vol.185 , pp. 1142-1149
    • Yu, F.S.1    Cornicelli, M.D.2    Kovach, M.A.3
  • 86
    • 33845249292 scopus 로고    scopus 로고
    • Protein delivery into eukaryotic cells by type III secretion machines
    • DOI 10.1038/nature05272, PII NATURE05272
    • Galan JE,Wolf-WatzH. Protein delivery into eukaryotic cells by type III secretionmachines. Nature 2006;444:567-573. (Pubitemid 44864429)
    • (2006) Nature , vol.444 , Issue.7119 , pp. 567-573
    • Galan, J.E.1    Wolf-Watz, H.2
  • 87
    • 69249157248 scopus 로고    scopus 로고
    • The type III secretion system of Pseudomonas aeruginosa: Infection by injection
    • Hauser AR. The type III secretion system of Pseudomonas aeruginosa: infection by injection. Nat RevMicrobiol 2009;7:654-665.
    • (2009) Nat RevMicrobiol , vol.7 , pp. 654-665
    • Hauser, A.R.1
  • 88
    • 4444342607 scopus 로고    scopus 로고
    • ExoU is a potent intracellular phospholipase
    • DOI 10.1111/j.1365-2958.2004.04194.x
    • Sato H, Frank DW. ExoU is a potent intracellular phospholipase. Mol Microbiol 2004;53: 1279-1290. (Pubitemid 39209104)
    • (2004) Molecular Microbiology , vol.53 , Issue.5 , pp. 1279-1290
    • Sato, H.1    Frank, D.W.2
  • 90
    • 0742288077 scopus 로고    scopus 로고
    • Epithelial Cell Polarity Alters Rho-GTPase Responses to Pseudomonas aeruginosa
    • DOI 10.1091/mbc.E03-08-0559
    • Kazmierczak BI, Mostov K, Engel JN. Epithelial cell polarity alters Rho-GTPase responses to Pseudomonas aeruginosa.Mol Biol Cell 2004;15:411-419. (Pubitemid 38146461)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.2 , pp. 411-419
    • Kazmierczak, B.I.1    Mostov, K.2    Engel, J.N.3
  • 91
    • 0036137206 scopus 로고    scopus 로고
    • In vivo Rho GTPase-activating protein activity of Pseudomonas aeruginosa cytotoxin Exos
    • DOI 10.1128/IAI.70.1.360-367.2002
    • Krall R, Sun J, Pederson KJ, Barbieri JT. In vivo rho GTPase-activating protein activity of Pseudomonas aeruginosa cytotoxin ExoS. Infect Immun 2002;70:360-367. (Pubitemid 34028636)
    • (2002) Infection and Immunity , vol.70 , Issue.1 , pp. 360-367
    • Krall, R.1    Sun, J.2    Pederson, K.J.3    Barbieri, J.T.4
  • 92
    • 59849110833 scopus 로고    scopus 로고
    • Role of Pseudomonas aeruginosa type III effectors in disease
    • Engel J, Balachandran P. Role of Pseudomonas aeruginosa type III effectors in disease. Curr Opin Microbiol 2009;12:61-66.
    • (2009) Curr Opin Microbiol , vol.12 , pp. 61-66
    • Engel, J.1    Balachandran, P.2
  • 93
    • 0034769748 scopus 로고    scopus 로고
    • Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa
    • Feltman H, Schulert G, Khan S, et al. Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa. Microbiology 2001;147:2659-2669. (Pubitemid 32976307)
    • (2001) Microbiology , vol.147 , Issue.10 , pp. 2659-2669
    • Feltman, H.1    Schulert, G.2    Khan, S.3    Jain, M.4    Peterson, L.5    Hauser, A.R.6
  • 95
    • 0041861176 scopus 로고    scopus 로고
    • Contribution of ExsA-regulated factors to corneal infection by cytotoxic and invasive Pseudomonas aeruginosa in a murine scarification model
    • DOI 10.1167/iovs.02-1302
    • Lee EJ, Cowell BA, Evans DJ, Fleiszig SM, et al. Contribution of ExsA-regulated factors to corneal infection by cytotoxic and invasive Pseudomonas aeruginosa in amurine scarification model. Invest Ophthalmol Vis Sci 2003;44:3892-3898. (Pubitemid 37047960)
    • (2003) Investigative Ophthalmology and Visual Science , vol.44 , Issue.9 , pp. 3892-3898
    • Lee, E.J.1    Cowell, B.A.2    Evans, D.J.3    Fleiszig, S.M.J.4
  • 96
    • 0034739007 scopus 로고    scopus 로고
    • Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen
    • Stover CK, Pham XQ, Erwin AL, et al. Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature 2000;406:959-964.
    • (2000) Nature , vol.406 , pp. 959-964
    • Stover, C.K.1    Pham, X.Q.2    Erwin, A.L.3
  • 97
    • 42949147704 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa induces membrane blebs in epithelial cells, which are utilized as a niche for intracellular replication and motility
    • DOI 10.1128/IAI.01221-07
    • Angus AA, Lee AA, Augustin DK, et al. Pseudomonas aeruginosa induces membrane blebs in epithelial cells, which are utilized as a niche for intracellular replication and motility. Infect Immun 2008;76:1992-2001. (Pubitemid 351656131)
    • (2008) Infection and Immunity , vol.76 , Issue.5 , pp. 1992-2001
    • Angus, A.A.1    Lee, A.A.2    Augustin, D.K.3    Lee, E.J.4    Evans, D.J.5    Fleiszig, S.M.J.6
  • 98
    • 78049431931 scopus 로고    scopus 로고
    • TheADP-ribosylationdomain of Pseudomonas aeruginosa ExoS is required for membrane Bleb-Niche formation and bacterial survival within epithelial cells
    • Angus AA, Evans DJ, Barbieri JT, Fleiszig SM.TheADP-ribosylationdomain of Pseudomonas aeruginosa ExoS is required for membrane Bleb-Niche formation and bacterial survival within epithelial cells. Infect Immun 2010;78(11):4500-4510.
    • (2010) Infect Immun , vol.78 , Issue.11 , pp. 4500-4510
    • Angus, A.A.1    Evans, D.J.2    Barbieri, J.T.3    Fleiszig, S.M.4
  • 99
    • 55949133222 scopus 로고    scopus 로고
    • Microbial biofilms in ophthalmology and infectious disease
    • Behlau I, Gilmore MS.Microbial biofilms in ophthalmology and infectious disease. Arch Ophthalmol 2008;126:1572-1581.
    • (2008) Arch Ophthalmol , vol.126 , pp. 1572-1581
    • Behlau, I.1    Gilmore, M.S.2
  • 100
    • 20944439684 scopus 로고    scopus 로고
    • Candida biofilm: A well-designed protected environment
    • DOI 10.1080/13693780500107554
    • Mukherjee PK, Zhou G, Munyon R, Ghannoum MA. Candida biofilm: a well-designed protected environment.MedMycol 2005;43:191-208. (Pubitemid 40867493)
    • (2005) Medical Mycology , vol.43 , Issue.3 , pp. 191-208
    • Mukherjee, P.K.1    Zhou, G.2    Munyon, R.3    Ghannoum, M.A.4
  • 101
    • 69749112208 scopus 로고    scopus 로고
    • Increased resistance of contact lens-related bacterial biofilms to antimicrobial activity of soft contact lens care solutions
    • Szczotka-Flynn LB, Imamura Y, Chandra J, et al. Increased resistance of contact lens-related bacterial biofilms to antimicrobial activity of soft contact lens care solutions. Cornea 2009;28:918-926.
    • (2009) Cornea , vol.28 , pp. 918-926
    • Szczotka-Flynn, L.B.1    Imamura, Y.2    Chandra, J.3
  • 102
    • 77949472586 scopus 로고    scopus 로고
    • GhannoumM.Microbial contamination of contact lenses, lens care solutions, and their accessories: A literature review
    • Szczotka-Flynn LB,Pearlman E,GhannoumM.Microbial contamination of contact lenses, lens care solutions, and their accessories: a literature review. Eye Contact Lens 2010;36:116-129.
    • (2010) Eye Contact Lens , vol.36 , pp. 116-129
    • Szczotka-Flynn, L.B.1    Pearlman, E.2
  • 104
    • 34247266001 scopus 로고    scopus 로고
    • Risk of corneal inflammatory events with silicone hydrogel and low Dk hydrogel extended contact lens wear: A meta-analysis
    • DOI 10.1097/OPX.0b013e3180421c47, PII 0000632420070400000006
    • Szczotka-Flynn L, Diaz M. Risk of corneal inflammatory events with silicone hydrogel and low dk hydrogel extended contact lens wear: a meta-analysis. Optom Vis Sci 2007;84:247-256. (Pubitemid 46624849)
    • (2007) Optometry and Vision Science , vol.84 , Issue.4 , pp. 247-256
    • Szczotka-Flynn, L.1    Diaz, M.2
  • 105
    • 80052549374 scopus 로고    scopus 로고
    • Diversity of bacteria at healthy human conjunctiva
    • Dong Q, Brulc JM, Iovieno A, et al. Diversity of bacteria at healthy human conjunctiva. Invest Ophthalmol Vis Sci 2011;52:5408-5413.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 5408-5413
    • Dong, Q.1    Brulc, J.M.2    Iovieno, A.3
  • 107
    • 0032819846 scopus 로고    scopus 로고
    • Differences in the pathogenesis of bacteria isolated from contact-lens-induced infiltrative conditions
    • DOI 10.1046/j.1440-1606.1999.00189.x
    • Willcox MD, Hume EB. Differences in the pathogenesis of bacteria isolated from contact-lensinduced infiltrative conditions. Aust N Z J Ophthalmol 1999;27:231-233. (Pubitemid 29429695)
    • (1999) Australian and New Zealand Journal of Ophthalmology , vol.27 , Issue.3-4 , pp. 231-233
    • Willcox, M.D.P.1    Hume, E.B.H.2
  • 108
    • 84863136696 scopus 로고    scopus 로고
    • ExoS and ExoT ADP ribosyltransferase activitiesmediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival
    • Sun Y, KarmakarM, Taylor PR, et al. ExoS and ExoT ADP ribosyltransferase activitiesmediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival. J Immunol 2012;188:1884-1895.
    • (2012) J Immunol , vol.188 , pp. 1884-1895
    • Sun, Y.1    Karmakar, M.2    Taylor, P.R.3
  • 109
    • 84872008873 scopus 로고    scopus 로고
    • Innate immune regulation of Serratia marcescens induced corneal inflammation and infection
    • Zhou R, Zhang R, Sun Y, et al. Innate immune regulation of Serratia marcescens induced corneal inflammation and infection. Invest Ophthalmol Vis Sci 2012;53(11):7382-7388.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , Issue.11 , pp. 7382-7388
    • Zhou, R.1    Zhang, R.2    Sun, Y.3
  • 112
    • 67651005204 scopus 로고    scopus 로고
    • Development of a Streptococcus pneumoniae keratitismodel inmice
    • Moore QC, 3rd, McCormick CC, Norcross EW, et al. Development of a Streptococcus pneumoniae keratitismodel inmice. Ophthalmic Res 2009;42:141-146.
    • (2009) Ophthalmic Res , vol.42 , pp. 141-146
    • Moore III, Q.C.1    McCormick, C.C.2    Norcross, E.W.3
  • 113
    • 45949095358 scopus 로고    scopus 로고
    • Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide
    • DOI 10.1189/jlb.0108076
    • Sun Y, Fox T, Adhikary G, et al. Inhibition of corneal inflammation by liposomal delivery of shortchain, C-6 ceramide. J Leukoc Biol 2008;83:1512-1521. (Pubitemid 351960333)
    • (2008) Journal of Leukocyte Biology , vol.83 , Issue.6 , pp. 1512-1521
    • Sun, Y.1    Fox, T.2    Adhikary, G.3    Kester, M.4    Pearlman, E.5
  • 114
    • 84880564589 scopus 로고    scopus 로고
    • Corneal inflammation is inhibited by the LFA-1 antagonist, lifitegrast (SAR 1118)
    • In press
    • Sun Y, Zhang R, Gadek TR, et al. Corneal inflammation is inhibited by the LFA-1 antagonist, lifitegrast (SAR 1118). J Ocul Pharmacol Ther 2013;29:In press.
    • J Ocul Pharmacol Ther , vol.2013 , pp. 29
    • Sun, Y.1    Zhang, R.2    Gadek, T.R.3


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