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Volumn 8, Issue 2, 2006, Pages 380-389

Toll-like receptor 2-mediated expression of β-defensin-2 in human corneal epithelial cells

Author keywords

Beta defensin; Corneal epithelium; Innate immunity; Toll like receptors

Indexed keywords

BETA DEFENSIN 1; BETA DEFENSIN 2; BETA DEFENSIN 3; I KAPPA B; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; NEUTRALIZING ANTIBODY; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA;

EID: 32244445123     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micinf.2005.07.006     Document Type: Article
Times cited : (110)

References (66)
  • 1
    • 0942301215 scopus 로고    scopus 로고
    • Distribution and shifting trends of bacterial keratitis in north China (1989-1998)
    • X. Sun, S. Deng, and R. Li Distribution and shifting trends of bacterial keratitis in north China (1989-1998) Br. J. Ophthalmol. 88 2004 165 166
    • (2004) Br. J. Ophthalmol. , vol.88 , pp. 165-166
    • Sun, X.1    Deng, S.2    Li, R.3
  • 2
    • 0033777744 scopus 로고    scopus 로고
    • Shifting trends in bacterial keratitis in south Florida and emerging resistance to fluoroquinolones
    • G. Alexandrakis, E.C. Alfonso, and D. Miller Shifting trends in bacterial keratitis in south Florida and emerging resistance to fluoroquinolones Ophthalmology 107 2000 1497 1502
    • (2000) Ophthalmology , vol.107 , pp. 1497-1502
    • Alexandrakis, G.1    Alfonso, E.C.2    Miller, D.3
  • 4
    • 0035425495 scopus 로고    scopus 로고
    • Innate immune responses of epithelial cells following infection with bacterial pathogens
    • D.J. Philpott, S.E. Girardin, and P.J. Sansonetti Innate immune responses of epithelial cells following infection with bacterial pathogens Curr. Opin. Immunol. 13 2001 410 416
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 410-416
    • Philpott, D.J.1    Girardin, S.E.2    Sansonetti, P.J.3
  • 5
    • 0037238970 scopus 로고    scopus 로고
    • Intestinal epithelial toll-like receptors: To protect. and serve?
    • A.T. Gewirtz Intestinal epithelial toll-like receptors: to protect. And serve? Curr. Pharm. Des. 9 2003 1 5
    • (2003) Curr. Pharm. Des. , vol.9 , pp. 1-5
    • Gewirtz, A.T.1
  • 6
    • 23444431775 scopus 로고    scopus 로고
    • Inflammatory responses of corneal epithelial cells to Pseudomonas aeruginosa infection
    • J. Zhang, X.Y. Wu, and F.S. FYu Inflammatory responses of corneal epithelial cells to Pseudomonas aeruginosa infection Curren Eye Research 30 2005 527 534
    • (2005) Curren Eye Research , vol.30 , pp. 527-534
    • Zhang, J.1    Wu, X.Y.2    Fyu, F.S.3
  • 7
    • 0141653750 scopus 로고    scopus 로고
    • Toll-like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin
    • J. Zhang, K. Xu, B. Ambati, and F.S. Yu Toll-like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin Invest. Ophthalmol. Vis. Sci. 44 2003 4247 4254
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 4247-4254
    • Zhang, J.1    Xu, K.2    Ambati, B.3    Yu, F.S.4
  • 8
    • 4644310244 scopus 로고    scopus 로고
    • Innate immune response of corneal epithelial cells to Staphylococcus aureus infection: Role of peptidoglycan in stimulating proinflammatory cytokine secretion
    • A. Kumar, J. Zhang, and F.S. Yu Innate immune response of corneal epithelial cells to Staphylococcus aureus infection: role of peptidoglycan in stimulating proinflammatory cytokine secretion Invest. Ophthalmol. Vis. Sci. 45 2004 3513 3522
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 3513-3522
    • Kumar, A.1    Zhang, J.2    Yu, F.S.3
  • 9
    • 0031252807 scopus 로고    scopus 로고
    • Activation of NF-kappaB in intestinal epithelial cells by enteropathogenic Escherichia coli
    • S.D. Savkovic, A. Koutsouris, and G. Hecht Activation of NF-kappaB in intestinal epithelial cells by enteropathogenic Escherichia coli Am. J. Physiol. 273 1997 C1160 C1167
    • (1997) Am. J. Physiol. , vol.273
    • Savkovic, S.D.1    Koutsouris, A.2    Hecht, G.3
  • 10
    • 0025999227 scopus 로고
    • Molecular cross talk between epithelial cells and pathogenic microorganisms
    • M.J. Wick, J.L. Madara, B.N. Fields, and S.J. Normark Molecular cross talk between epithelial cells and pathogenic microorganisms Cell 67 1991 651 659
    • (1991) Cell , vol.67 , pp. 651-659
    • Wick, M.J.1    Madara, J.L.2    Fields, B.N.3    Normark, S.J.4
  • 11
    • 0347362785 scopus 로고    scopus 로고
    • Respiratory syncytial virus up-regulates TLR4 and sensitizes airway epithelial cells to endotoxin
    • M.M. Monick, T.O. Yarovinsky, and L.S. Powers Respiratory syncytial virus up-regulates TLR4 and sensitizes airway epithelial cells to endotoxin J. Biol. Chem. 278 2003 53035 53044
    • (2003) J. Biol. Chem. , vol.278 , pp. 53035-53044
    • Monick, M.M.1    Yarovinsky, T.O.2    Powers, L.S.3
  • 12
    • 0032526639 scopus 로고    scopus 로고
    • Low grade rhinovirus infection induces a prolonged release of IL-8 in pulmonary epithelium
    • S.L. Johnston, A. Papi, and P.J. Bates Low grade rhinovirus infection induces a prolonged release of IL-8 in pulmonary epithelium J. Immunol. 160 1998 6172 6181
    • (1998) J. Immunol. , vol.160 , pp. 6172-6181
    • Johnston, S.L.1    Papi, A.2    Bates, P.J.3
  • 13
    • 0141955094 scopus 로고    scopus 로고
    • Viral induction of inflammatory cytokines in human epithelial cells follows a p38 mitogen-activated protein kinase-dependent but NF-kappa B-independent pathway
    • T.R. Meusel, and F. Imani Viral induction of inflammatory cytokines in human epithelial cells follows a p38 mitogen-activated protein kinase-dependent but NF-kappa B-independent pathway J. Immunol. 171 2003 3768 3774
    • (2003) J. Immunol. , vol.171 , pp. 3768-3774
    • Meusel, T.R.1    Imani, F.2
  • 14
    • 18744380330 scopus 로고    scopus 로고
    • Polymorphonuclear leukocyte migration across model intestinal epithelia enhances Salmonella typhimurium killing via the epithelial derived cytokine, IL-6
    • W.J. Nadeau, T.G. Pistole, and B.A. McCormick Polymorphonuclear leukocyte migration across model intestinal epithelia enhances Salmonella typhimurium killing via the epithelial derived cytokine, IL-6 Microbes Infect. 4 2002 1379 1387
    • (2002) Microbes Infect. , vol.4 , pp. 1379-1387
    • Nadeau, W.J.1    Pistole, T.G.2    McCormick, B.A.3
  • 15
    • 1042269503 scopus 로고    scopus 로고
    • Innate immunity in the lung: How epithelial cells fight against respiratory pathogens
    • R. Bals, and P.S. Hiemstra Innate immunity in the lung: how epithelial cells fight against respiratory pathogens Eur. Respir. J. 23 2004 327 333
    • (2004) Eur. Respir. J. , vol.23 , pp. 327-333
    • Bals, R.1    Hiemstra, P.S.2
  • 16
    • 0035856965 scopus 로고    scopus 로고
    • Bug detectors
    • T. Kaisho, and S. Akira Bug detectors Nature 414 2001 701 703
    • (2001) Nature , vol.414 , pp. 701-703
    • Kaisho, T.1    Akira, S.2
  • 19
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • S. Akira, and K. Takeda Toll-like receptor signalling Nat. Rev. Immunol. 4 2004 499 511
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 20
    • 0034043956 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression
    • A.E. Medvedev, K.M. Kopydlowski, and S.N. Vogel Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression J. Immunol. 164 2000 5564 5574
    • (2000) J. Immunol. , vol.164 , pp. 5564-5574
    • Medvedev, A.E.1    Kopydlowski, K.M.2    Vogel, S.N.3
  • 21
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • S. Akira, K. Takeda, and T. Kaisho Toll-like receptors: critical proteins linking innate and acquired immunity Nat. Immunol. 2 2001 675 680
    • (2001) Nat. Immunol. , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 22
    • 0034669910 scopus 로고    scopus 로고
    • Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection
    • O. Takeuchi, K. Hoshino, and S. Akira Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection J. Immunol. 165 2000 5392 5396
    • (2000) J. Immunol. , vol.165 , pp. 5392-5396
    • Takeuchi, O.1    Hoshino, K.2    Akira, S.3
  • 23
    • 0038664380 scopus 로고    scopus 로고
    • The role of Toll-like receptor 2 in microbial disease and immunity
    • L.M. Wetzler The role of Toll-like receptor 2 in microbial disease and immunity Vaccine 21 Suppl. 2 2003 S55 S60
    • (2003) Vaccine , vol.21 , Issue.2 SUPPL.
    • Wetzler, L.M.1
  • 24
    • 0033794461 scopus 로고    scopus 로고
    • A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection
    • E. Lorenz, J.P. Mira, K.L. Cornish, N.C. Arbour, and D.A. Schwartz A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection Infect. Immun. 68 2000 6398 6401
    • (2000) Infect. Immun. , vol.68 , pp. 6398-6401
    • Lorenz, E.1    Mira, J.P.2    Cornish, K.L.3    Arbour, N.C.4    Schwartz, D.A.5
  • 25
    • 0037307854 scopus 로고    scopus 로고
    • Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: Implications for host-microbial interactions in the gut
    • G. Melmed, L.S. Thomas, and N. Lee Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut J. Immunol. 170 2003 1406 1415
    • (2003) J. Immunol. , vol.170 , pp. 1406-1415
    • Melmed, G.1    Thomas, L.S.2    Lee, N.3
  • 26
    • 0017027527 scopus 로고
    • Herpetic stromal keratitis-evidence for cell-mediated immunopathogenesis
    • J.F. Metcalf, and H.E. Kaufman Herpetic stromal keratitis-evidence for cell-mediated immunopathogenesis Am. J. Ophthalmol. 82 1976 827 834
    • (1976) Am. J. Ophthalmol. , vol.82 , pp. 827-834
    • Metcalf, J.F.1    Kaufman, H.E.2
  • 27
    • 0033017822 scopus 로고    scopus 로고
    • Antimicrobial defensin peptides of the human ocular surface
    • R.J. Haynes, P.J. Tighe, and H.S. Dua Antimicrobial defensin peptides of the human ocular surface Br. J. Ophthalmol. 83 1999 737 741
    • (1999) Br. J. Ophthalmol. , vol.83 , pp. 737-741
    • Haynes, R.J.1    Tighe, P.J.2    Dua, H.S.3
  • 28
    • 3242755069 scopus 로고    scopus 로고
    • Human beta-defensin 2 is induced by interleukin-1beta in the corneal epithelial cells
    • J.S. Shin, C.W. Kim, Y.S. Kwon, and J.C. Kim Human beta-defensin 2 is induced by interleukin-1beta in the corneal epithelial cells Exp. Mol. Med. 36 2004 204 210
    • (2004) Exp. Mol. Med. , vol.36 , pp. 204-210
    • Shin, J.S.1    Kim, C.W.2    Kwon, Y.S.3    Kim, J.C.4
  • 29
    • 0034924159 scopus 로고    scopus 로고
    • Human beta-defensin 2 is up-regulated during re-epithelialization of the cornea
    • A.M. McDermott, R.L. Redfern, and B. Zhang Human beta-defensin 2 is up-regulated during re-epithelialization of the cornea Curr. Eye Res. 22 2001 64 67
    • (2001) Curr. Eye Res. , vol.22 , pp. 64-67
    • McDermott, A.M.1    Redfern, R.L.2    Zhang, B.3
  • 30
    • 0037406799 scopus 로고    scopus 로고
    • Defensin expression by the cornea: Multiple signalling pathways mediate IL-1beta stimulation of hBD-2 expression by human corneal epithelial cells
    • A.M. McDermott, R.L. Redfern, and B. Zhang Defensin expression by the cornea: multiple signalling pathways mediate IL-1beta stimulation of hBD-2 expression by human corneal epithelial cells Invest. Ophthalmol. Vis. Sci. 44 2003 1859 1865
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 1859-1865
    • McDermott, A.M.1    Redfern, R.L.2    Zhang, B.3
  • 31
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: Antimicrobial peptides of innate immunity
    • T. Ganz Defensins: antimicrobial peptides of innate immunity Nat. Rev. Immunol. 3 2003 710 720
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 710-720
    • Ganz, T.1
  • 32
    • 0032734313 scopus 로고    scopus 로고
    • Expression and regulation of the human {beta}-defensins hBD-1 and hBD-2 in intestinal epithelium
    • D.A. O'Neil, E.M. Porter, and D. Elewaut Expression and regulation of the human {beta}-defensins hBD-1 and hBD-2 in intestinal epithelium J. Immunol. 163 1999 6718 6724
    • (1999) J. Immunol. , vol.163 , pp. 6718-6724
    • O'Neil, D.A.1    Porter, E.M.2    Elewaut, D.3
  • 33
    • 0033865538 scopus 로고    scopus 로고
    • Differential expression of human alpha- and beta-defensins mRNA in gastrointestinal epithelia
    • M. Frye, J. Bargon, B. Lembcke, T.O. Wagner, and R. Gropp Differential expression of human alpha- and beta-defensins mRNA in gastrointestinal epithelia Eur. J. Clin. Invest. 30 2000 695 701
    • (2000) Eur. J. Clin. Invest. , vol.30 , pp. 695-701
    • Frye, M.1    Bargon, J.2    Lembcke, B.3    Wagner, T.O.4    Gropp, R.5
  • 34
    • 0035937107 scopus 로고    scopus 로고
    • Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic
    • J. Harder, J. Bartels, E. Christophers, and J.M. Schroder Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic J. Biol. Chem. 276 2001 5707 5713
    • (2001) J. Biol. Chem. , vol.276 , pp. 5707-5713
    • Harder, J.1    Bartels, J.2    Christophers, E.3    Schroder, J.M.4
  • 35
    • 0035941137 scopus 로고    scopus 로고
    • Production of beta-defensin-2 by human colonic epithelial cells induced by Salmonella enteritidis flagella filament structural protein
    • A. Takahashi, A. Wada, and K. Ogushi Production of beta-defensin-2 by human colonic epithelial cells induced by Salmonella enteritidis flagella filament structural protein FEBS Lett. 508 2001 484 488
    • (2001) FEBS Lett. , vol.508 , pp. 484-488
    • Takahashi, A.1    Wada, A.2    Ogushi, K.3
  • 36
    • 0032731116 scopus 로고    scopus 로고
    • Ocular surface epithelia express mRNA for human beta defensin-2
    • N. McNamara, R. Van, O.S. Tuchin, and S.M. Fleiszig Ocular surface epithelia express mRNA for human beta defensin-2 Exp. Eye Res. 69 1999 483 490
    • (1999) Exp. Eye Res. , vol.69 , pp. 483-490
    • McNamara, N.1    Van, R.2    Tuchin, O.S.3    Fleiszig, S.M.4
  • 37
    • 0034125829 scopus 로고    scopus 로고
    • Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but Not IL-6, induce human beta-defensin-2 in respiratory epithelia
    • J. Harder, U. Meyer-Hoffert, and L.M. Teran Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but Not IL-6, induce human beta-defensin-2 in respiratory epithelia Am. J. Respir. Cell. Mol. Biol. 22 2000 714 721
    • (2000) Am. J. Respir. Cell. Mol. Biol. , vol.22 , pp. 714-721
    • Harder, J.1    Meyer-Hoffert, U.2    Teran, L.M.3
  • 38
    • 10744222928 scopus 로고    scopus 로고
    • Toll-like receptor expression in human keratinocytes: Nuclear factor kappaB controlled gene activation by Staphylococcus aureus is toll-like receptor 2 but not toll-like receptor 4 or platelet activating factor receptor dependent
    • M. Mempel, V. Voelcker, and G. Kollisch Toll-like receptor expression in human keratinocytes: nuclear factor kappaB controlled gene activation by Staphylococcus aureus is toll-like receptor 2 but not toll-like receptor 4 or platelet activating factor receptor dependent J. Invest. Dermatol. 121 2003 1389 1396
    • (2003) J. Invest. Dermatol. , vol.121 , pp. 1389-1396
    • Mempel, M.1    Voelcker, V.2    Kollisch, G.3
  • 39
    • 0030932830 scopus 로고    scopus 로고
    • T-cell proliferation to superantigen-releasing Staphylococcus aureus by MHC class II-bearing keratinocytes under protection from bacterial cytolysin
    • Y. Tokura, F. Furukawa, and H. Wakita T-cell proliferation to superantigen-releasing Staphylococcus aureus by MHC class II-bearing keratinocytes under protection from bacterial cytolysin J. Invest. Dermatol. 108 1997 488 494
    • (1997) J. Invest. Dermatol. , vol.108 , pp. 488-494
    • Tokura, Y.1    Furukawa, F.2    Wakita, H.3
  • 40
    • 0036288508 scopus 로고    scopus 로고
    • A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status
    • J.G. Rheinwald, W.C. Hahn, and M.R. Ramsey A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status Mol. Cell. Biol. 22 2002 5157 5172
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5157-5172
    • Rheinwald, J.G.1    Hahn, W.C.2    Ramsey, M.R.3
  • 41
    • 0038237453 scopus 로고    scopus 로고
    • Mucin gene expression in immortalized human corneal-limbal and conjunctival epithelial cell lines
    • I.K. Gipson, S. Spurr-Michaud, and P. Argueso Mucin gene expression in immortalized human corneal-limbal and conjunctival epithelial cell lines Invest. Ophthalmol. Vis. Sci. 44 2003 2496 2506
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 2496-2506
    • Gipson, I.K.1    Spurr-Michaud, S.2    Argueso, P.3
  • 42
    • 4344705045 scopus 로고    scopus 로고
    • Intracellularly expressed TLR2s and TLR4s contribution to an immunosilent environment at the ocular mucosal epithelium
    • M. Ueta, T. Nochi, and M.H. Jang Intracellularly expressed TLR2s and TLR4s contribution to an immunosilent environment at the ocular mucosal epithelium J. Immunol. 173 2004 3337 3347
    • (2004) J. Immunol. , vol.173 , pp. 3337-3347
    • Ueta, M.1    Nochi, T.2    Jang, M.H.3
  • 43
    • 0037018107 scopus 로고    scopus 로고
    • Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells
    • M.W. Hornef, T. Frisan, A. Vandewalle, S. Normark, and A. Richter-Dahlfors Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells J. Exp. Med. 195 2002 559 570
    • (2002) J. Exp. Med. , vol.195 , pp. 559-570
    • Hornef, M.W.1    Frisan, T.2    Vandewalle, A.3    Normark, S.4    Richter-Dahlfors, A.5
  • 44
    • 1642494708 scopus 로고    scopus 로고
    • Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: Evidence for an intracellular compartmentalization of TLR4
    • L. Guillot, S. Medjane, and K. Le-Barillec Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular compartmentalization of TLR4 J. Biol. Chem. 279 2004 2712 2718
    • (2004) J. Biol. Chem. , vol.279 , pp. 2712-2718
    • Guillot, L.1    Medjane, S.2    Le-Barillec, K.3
  • 45
    • 0034030506 scopus 로고    scopus 로고
    • Truncation mutants of the tight junction protein ZO-1 disrupt corneal epithelial cell morphology
    • S.W. Ryeom, D. Paul, and D.A. Goodenough Truncation mutants of the tight junction protein ZO-1 disrupt corneal epithelial cell morphology Mol. Biol. Cell 11 2000 1687 1696
    • (2000) Mol. Biol. Cell , vol.11 , pp. 1687-1696
    • Ryeom, S.W.1    Paul, D.2    Goodenough, D.A.3
  • 46
    • 0034018607 scopus 로고    scopus 로고
    • Investigation of beta defensin gene expression in the ocular anterior segment by semiquantitative RT-PCR
    • O.J. Lehmann, I.R. Hussain, and P.J. Watt Investigation of beta defensin gene expression in the ocular anterior segment by semiquantitative RT-PCR Br. J. Ophthalmol. 84 2000 523 526
    • (2000) Br. J. Ophthalmol. , vol.84 , pp. 523-526
    • Lehmann, O.J.1    Hussain, I.R.2    Watt, P.J.3
  • 47
    • 4644298916 scopus 로고    scopus 로고
    • Minireview: Functions of the renal tract epithelium in coordinating the innate immune response to infection
    • P. Chowdhury, S.H. Sacks, and N.S. Sheerin Minireview: functions of the renal tract epithelium in coordinating the innate immune response to infection Kidney Int. 66 2004 1334 1344
    • (2004) Kidney Int. , vol.66 , pp. 1334-1344
    • Chowdhury, P.1    Sacks, S.H.2    Sheerin, N.S.3
  • 49
    • 13944271838 scopus 로고    scopus 로고
    • Activation of Toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation
    • A.C. Johnson, F.P. Heinzel, and E. Diaconu Activation of Toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation Invest. Ophthalmol. Vis. Sci. 46 2005 589 595
    • (2005) Invest. Ophthalmol. Vis. Sci. , vol.46 , pp. 589-595
    • Johnson, A.C.1    Heinzel, F.P.2    Diaconu, E.3
  • 50
    • 7944220803 scopus 로고    scopus 로고
    • Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition
    • L.H. Travassos, S.E. Girardin, and D.J. Philpott Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition EMBO Rep. 5 2004 1000 1006
    • (2004) EMBO Rep. , vol.5 , pp. 1000-1006
    • Travassos, L.H.1    Girardin, S.E.2    Philpott, D.J.3
  • 51
    • 0037218547 scopus 로고    scopus 로고
    • Induction of in vitro reprogramming by toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: Effects of TLR "homotolerance" versus "heterotolerance" on NF-{kappa}B signaling pathway components
    • M.A. Dobrovolskaia, A.E. Medvedev, and K.E. Thomas Induction of in vitro reprogramming by toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-{kappa}B signaling pathway components J. Immunol. 170 2003 508 519
    • (2003) J. Immunol. , vol.170 , pp. 508-519
    • Dobrovolskaia, M.A.1    Medvedev, A.E.2    Thomas, K.E.3
  • 52
    • 0036178642 scopus 로고    scopus 로고
    • Human beta-defensin-2 production in keratinocytes is regulated by interleukin-1, bacteria, and the state of differentiation
    • A.Y. Liu, D. Destoumieux, and A.V. Wong Human beta-defensin-2 production in keratinocytes is regulated by interleukin-1, bacteria, and the state of differentiation J. Invest. Dermatol. 118 2002 275 281
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 275-281
    • Liu, A.Y.1    Destoumieux, D.2    Wong, A.V.3
  • 53
    • 0037218616 scopus 로고    scopus 로고
    • By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide
    • L. Liu, A.A. Roberts, and T. Ganz By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide J. Immunol. 170 2003 575 580
    • (2003) J. Immunol. , vol.170 , pp. 575-580
    • Liu, L.1    Roberts, A.A.2    Ganz, T.3
  • 54
    • 0344483901 scopus 로고    scopus 로고
    • Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands
    • M. Mathews, H.P. Jia, and J.M. Guthmiller Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands Infect. Immun. 67 1999 2740 2745
    • (1999) Infect. Immun. , vol.67 , pp. 2740-2745
    • Mathews, M.1    Jia, H.P.2    Guthmiller, J.M.3
  • 55
    • 0034020351 scopus 로고    scopus 로고
    • Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: Multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier
    • S. Krisanaprakornkit, J.R. Kimball, and A. Weinberg Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier Infect. Immun. 68 2000 2907 2915
    • (2000) Infect. Immun. , vol.68 , pp. 2907-2915
    • Krisanaprakornkit, S.1    Kimball, J.R.2    Weinberg, A.3
  • 56
    • 0036970572 scopus 로고    scopus 로고
    • Bactericidal activity of renal tubular cells: The putative role of human beta-defensins
    • M. Nitschke, S. Wiehl, P.C. Baer, and B. Kreft Bactericidal activity of renal tubular cells: the putative role of human beta-defensins Exp. Nephrol. 10 2002 332 337
    • (2002) Exp. Nephrol. , vol.10 , pp. 332-337
    • Nitschke, M.1    Wiehl, S.2    Baer, P.C.3    Kreft, B.4
  • 57
    • 0037130950 scopus 로고    scopus 로고
    • Expression of human beta-defensins 1 and 2 in kidneys with chronic bacterial infection
    • J. Lehmann, M. Retz, and J. Harder Expression of human beta-defensins 1 and 2 in kidneys with chronic bacterial infection BMC Infect. Dis. 2 2002 20
    • (2002) BMC Infect. Dis. , vol.2 , pp. 20
    • Lehmann, J.1    Retz, M.2    Harder, J.3
  • 58
    • 0141483491 scopus 로고    scopus 로고
    • Airway epithelia regulate expression of human beta-defensin 2 through Toll-like receptor 2
    • X. Wang, Z. Zhang, and J.P. Louboutin Airway epithelia regulate expression of human beta-defensin 2 through Toll-like receptor 2 FASEB J. 17 2003 1727 1729
    • (2003) FASEB J. , vol.17 , pp. 1727-1729
    • Wang, X.1    Zhang, Z.2    Louboutin, J.P.3
  • 59
    • 0346366980 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2
    • C.J. Hertz, Q. Wu, and E.M. Porter Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2 J. Immunol. 171 2003 6820 6826
    • (2003) J. Immunol. , vol.171 , pp. 6820-6826
    • Hertz, C.J.1    Wu, Q.2    Porter, E.M.3
  • 60
    • 0037250369 scopus 로고    scopus 로고
    • Keratinocyte expression of human beta defensin 2 following bacterial infection: Role in cutaneous host defense
    • J.G. Dinulos, L. Mentele, L.P. Fredericks, B.A. Dale, and G.L. Darmstadt Keratinocyte expression of human beta defensin 2 following bacterial infection: role in cutaneous host defense Clin. Diagn. Lab. Immunol. 10 2003 161 166
    • (2003) Clin. Diagn. Lab. Immunol. , vol.10 , pp. 161-166
    • Dinulos, J.G.1    Mentele, L.2    Fredericks, L.P.3    Dale, B.A.4    Darmstadt, G.L.5
  • 61
    • 0032548181 scopus 로고    scopus 로고
    • Structure and mapping of the human beta-defensin HBD-2 gene and its expression at sites of inflammation
    • L. Liu, L. Wang, and H.P. Jia Structure and mapping of the human beta-defensin HBD-2 gene and its expression at sites of inflammation Gene 222 1998 237 244
    • (1998) Gene , vol.222 , pp. 237-244
    • Liu, L.1    Wang, L.2    Jia, H.P.3
  • 62
    • 0141928681 scopus 로고    scopus 로고
    • Regulation of expression of beta-defensins: Endogenous enteric peptide antibiotics
    • D.A. O'Neil Regulation of expression of beta-defensins: endogenous enteric peptide antibiotics Mol. Immunol. 40 2003 445 450
    • (2003) Mol. Immunol. , vol.40 , pp. 445-450
    • O'Neil, D.A.1
  • 64
    • 0033213989 scopus 로고    scopus 로고
    • Epithelial antimicrobial peptides: Innate local host response elements
    • J.M. Schroder Epithelial antimicrobial peptides: innate local host response elements Cell. Mol. Life Sci. 56 1999 32 46
    • (1999) Cell. Mol. Life Sci. , vol.56 , pp. 32-46
    • Schroder, J.M.1
  • 65
    • 0037040913 scopus 로고    scopus 로고
    • The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus
    • D.J. Schibli, H.N. Hunter, and V. Aseyev The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus J. Biol. Chem. 277 2002 8279 8289
    • (2002) J. Biol. Chem. , vol.277 , pp. 8279-8289
    • Schibli, D.J.1    Hunter, H.N.2    Aseyev, V.3
  • 66
    • 18244375285 scopus 로고    scopus 로고
    • The spectrum of antimicrobial peptide expression at the ocular surface
    • R.S. McIntosh, J.E. Cade, and M. Al-Abed The spectrum of antimicrobial peptide expression at the ocular surface Invest. Ophthalmol. Vis. Sci. 46 2005 1379 1385
    • (2005) Invest. Ophthalmol. Vis. Sci. , vol.46 , pp. 1379-1385
    • McIntosh, R.S.1    Cade, J.E.2    Al-Abed, M.3


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