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Volumn 76, Issue 1, 2008, Pages 89-96

Flagellin suppresses the inflammatory response and enhances bacterial clearance in a murine model of Peudomonas aeruginosa keratitis

Author keywords

[No Author keywords available]

Indexed keywords

CATHELICIDIN; FLAGELLIN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; NITRIC OXIDE SYNTHASE; POLYPEPTIDE ANTIBIOTIC AGENT; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

EID: 37749037714     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01232-07     Document Type: Article
Times cited : (64)

References (56)
  • 1
    • 0033968432 scopus 로고    scopus 로고
    • The role of nitric oxide in innate immunity
    • Bogdan, C., M. Rollinghoff, and A. Diefenbach. 2000. The role of nitric oxide in innate immunity. Immunol. Rev. 173:17-26.
    • (2000) Immunol. Rev , vol.173 , pp. 17-26
    • Bogdan, C.1    Rollinghoff, M.2    Diefenbach, A.3
  • 2
    • 33845600274 scopus 로고    scopus 로고
    • Systemic NO production during (septic) shock depends on parenchymal and not on hematopoietic cells: In vivo iNOS expression pattern in (septic) shock
    • Bultinck, J., P. Sips, L. Vakaet, P. Brouckaert, and A. Cauwels. 2006. Systemic NO production during (septic) shock depends on parenchymal and not on hematopoietic cells: in vivo iNOS expression pattern in (septic) shock. FASEB J. 20:2363-2365.
    • (2006) FASEB J , vol.20 , pp. 2363-2365
    • Bultinck, J.1    Sips, P.2    Vakaet, L.3    Brouckaert, P.4    Cauwels, A.5
  • 3
    • 34247235029 scopus 로고    scopus 로고
    • Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function
    • Cario, E. L., G. U. Gerken, and D. A. Podolsky. 2007. Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function. Gastroenterology 132:1359-1374.
    • (2007) Gastroenterology , vol.132 , pp. 1359-1374
    • Cario, E.L.1    Gerken, G.U.2    Podolsky, D.A.3
  • 4
    • 0035185373 scopus 로고    scopus 로고
    • What is the role of nitric oxide in murine and human host defense against tuberculosis? Current knowledge
    • Chan, E. D., J. Chan, and N. W. Schluger. 2001. What is the role of nitric oxide in murine and human host defense against tuberculosis? Current knowledge. Am. J. Respir. Cell Mol. Biol. 25:606-612.
    • (2001) Am. J. Respir. Cell Mol. Biol , vol.25 , pp. 606-612
    • Chan, E.D.1    Chan, J.2    Schluger, N.W.3
  • 5
    • 26844567701 scopus 로고    scopus 로고
    • Synergistic effect of antibacterial agents human [beta]-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli
    • Chen, X., F. Niyonsaba, H. Ushio, D. Okuda, I. Nagaoka, S. Ikeda, K. Okumura, and H. Ogawa. 2005. Synergistic effect of antibacterial agents human [beta]-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli. J. Dermatol. Sci. 40:123-132.
    • (2005) J. Dermatol. Sci , vol.40 , pp. 123-132
    • Chen, X.1    Niyonsaba, F.2    Ushio, H.3    Okuda, D.4    Nagaoka, I.5    Ikeda, S.6    Okumura, K.7    Ogawa, H.8
  • 6
    • 28244478101 scopus 로고    scopus 로고
    • Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-kappaB
    • Chen, X. M., S. P. O'Hara, J. B. Nelson, P. L. Splinter, A. J. Small, P. S. Tietz, A. H. Limper, and N. F. LaRusso. 2005. Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-kappaB. J. Immunol. 175: 7447-7456.
    • (2005) J. Immunol , vol.175 , pp. 7447-7456
    • Chen, X.M.1    O'Hara, S.P.2    Nelson, J.B.3    Splinter, P.L.4    Small, A.J.5    Tietz, P.S.6    Limper, A.H.7    LaRusso, N.F.8
  • 8
    • 0033975132 scopus 로고    scopus 로고
    • KC production in the cornea in response to Pseudomonas aeruginosa challenge
    • Cole, N., S. Bao, A. Thakur, M. Willcox, and A. J. Husband. 2000. KC production in the cornea in response to Pseudomonas aeruginosa challenge. Immunol. Cell Biol. 78:1-4.
    • (2000) Immunol. Cell Biol , vol.78 , pp. 1-4
    • Cole, N.1    Bao, S.2    Thakur, A.3    Willcox, M.4    Husband, A.J.5
  • 9
    • 2342430991 scopus 로고    scopus 로고
    • Molecular mechanisms of endotoxin tolerance
    • Fan, H., and J. A. Cook. 2004. Molecular mechanisms of endotoxin tolerance. J. Endotoxin Res. 10:71-84.
    • (2004) J. Endotoxin Res , vol.10 , pp. 71-84
    • Fan, H.1    Cook, J.A.2
  • 12
    • 0014643535 scopus 로고    scopus 로고
    • Greisman, S. E., E. J. Young, and F. A. Carozza, Jr. 1969. Mechanisms of endotoxin tolerance. V. Specificity of the early and late phases of pyrogenic tolerance. J. Immunol. 103:1223-1236.
    • Greisman, S. E., E. J. Young, and F. A. Carozza, Jr. 1969. Mechanisms of endotoxin tolerance. V. Specificity of the early and late phases of pyrogenic tolerance. J. Immunol. 103:1223-1236.
  • 13
    • 0842346487 scopus 로고    scopus 로고
    • Corneal response to Pseudomonas aeruginosa infection
    • Hazlett, L. D. 2004. Corneal response to Pseudomonas aeruginosa infection. Prog. Retin. Eye Res. 23:1-30.
    • (2004) Prog. Retin. Eye Res , vol.23 , pp. 1-30
    • Hazlett, L.D.1
  • 15
    • 0034055211 scopus 로고    scopus 로고
    • Increased severity of Pseudomonas aeruginosa corneal infection in strains of mice designated as Th1 versus Th2 responsive
    • Hazlett, L. D., S. McClellan, B. Kwon, and R. Barrett. 2000. Increased severity of Pseudomonas aeruginosa corneal infection in strains of mice designated as Th1 versus Th2 responsive. Investig. Ophthalmol. Vis. Sci. 41:805-810.
    • (2000) Investig. Ophthalmol. Vis. Sci , vol.41 , pp. 805-810
    • Hazlett, L.D.1    McClellan, S.2    Kwon, B.3    Barrett, R.4
  • 18
    • 0041842728 scopus 로고    scopus 로고
    • Analysis of Pseudomonas aeruginosa corneal infection using an oligonucleotide microarray
    • Huang, X., and L. D. Hazlett. 2003. Analysis of Pseudomonas aeruginosa corneal infection using an oligonucleotide microarray. Investig. Ophthalmol. Vis. Sci. 44:3409-3416.
    • (2003) Investig. Ophthalmol. Vis. Sci , vol.44 , pp. 3409-3416
    • Huang, X.1    Hazlett, L.D.2
  • 20
    • 84949117829 scopus 로고    scopus 로고
    • Toll-like receptors in the cornea. The ocular surface
    • Johnson, A., and E. Pearlman. 2005. Toll-like receptors in the cornea. The ocular surface. Ocul. Surf. 3:S187-S189.
    • (2005) Ocul. Surf , vol.3
    • Johnson, A.1    Pearlman, E.2
  • 22
    • 33846833924 scopus 로고    scopus 로고
    • Staphylococcus aureus protein A induced inflammatory response in human corneal epithelial cells
    • Kumar, A., A. M. Tassopoulos, Q. Li, and F. S. Yu. 2007. Staphylococcus aureus protein A induced inflammatory response in human corneal epithelial cells. Biochem. Biophys. Res. Commun. 354:955-961.
    • (2007) Biochem. Biophys. Res. Commun , vol.354 , pp. 955-961
    • Kumar, A.1    Tassopoulos, A.M.2    Li, Q.3    Yu, F.S.4
  • 23
    • 35748965018 scopus 로고    scopus 로고
    • Modulation of corneal epithelial innate immune response to Pseudomonas infection by flagellin pretreatment
    • Kumar, A., J. Yin, J. Zhang, and F. Yu. 2007. Modulation of corneal epithelial innate immune response to Pseudomonas infection by flagellin pretreatment. Investig. Ophthalmol. Vis. Sci. 48:4664-4670.
    • (2007) Investig. Ophthalmol. Vis. Sci , vol.48 , pp. 4664-4670
    • Kumar, A.1    Yin, J.2    Zhang, J.3    Yu, F.4
  • 24
    • 4644310244 scopus 로고    scopus 로고
    • Innate immune response of corneal epithelial cells to Staphylococcus aureus infection: Role of peptidoglycan in stimulating proinflammatory cytokine secretion
    • Kumar, A., J. Zhang, and F. S. Yu. 2004. Innate immune response of corneal epithelial cells to Staphylococcus aureus infection: role of peptidoglycan in stimulating proinflammatory cytokine secretion. Investig. Ophthalmol. Vis. Sci. 45:3513-3522.
    • (2004) Investig. Ophthalmol. Vis. Sci , vol.45 , pp. 3513-3522
    • Kumar, A.1    Zhang, J.2    Yu, F.S.3
  • 25
    • 32244445123 scopus 로고    scopus 로고
    • Toll-like receptor 2-mediated expression of beta-defensin-2 in human corneal epithelial cells
    • Kumar, A., J. Zhang, and F. S. Yu. 2006. Toll-like receptor 2-mediated expression of beta-defensin-2 in human corneal epithelial cells. Microbes Infect. 8:380-389.
    • (2006) Microbes Infect , vol.8 , pp. 380-389
    • Kumar, A.1    Zhang, J.2    Yu, F.S.3
  • 27
    • 0035158914 scopus 로고    scopus 로고
    • Improved innate immunity of endotoxin-tolerant mice increases resistance to Salmonella enterica serovar Typhimurium infection despite attenuated cytokine response
    • Lehner, M. D., J. Ittner, D. S. Bundschuh, N. van Rooijen, A. Wendel, and T. Hartung. 2001. Improved innate immunity of endotoxin-tolerant mice increases resistance to Salmonella enterica serovar Typhimurium infection despite attenuated cytokine response. Infect. Immun. 69:463-471.
    • (2001) Infect. Immun , vol.69 , pp. 463-471
    • Lehner, M.D.1    Ittner, J.2    Bundschuh, D.S.3    van Rooijen, N.4    Wendel, A.5    Hartung, T.6
  • 28
    • 0035871626 scopus 로고    scopus 로고
    • Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators
    • Lehner, M. D., S. Morath, K. S. Michelsen, R. R. Schumann, and T. Hartung. 2001. Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J. Immunol. 166:5161-5167.
    • (2001) J. Immunol , vol.166 , pp. 5161-5167
    • Lehner, M.D.1    Morath, S.2    Michelsen, K.S.3    Schumann, R.R.4    Hartung, T.5
  • 29
    • 33746431489 scopus 로고    scopus 로고
    • Bacterial lipoprotein-induced self-tolerance and cross-tolerance to LPS are associated with reduced IRAK-1 expression and MyD88-IRAK complex formation
    • Li, C. H., J. H. Wang, and H. P. Redmond. 2006. Bacterial lipoprotein-induced self-tolerance and cross-tolerance to LPS are associated with reduced IRAK-1 expression and MyD88-IRAK complex formation. J. Leukoc. Biol. 79:867-875.
    • (2006) J. Leukoc. Biol , vol.79 , pp. 867-875
    • Li, C.H.1    Wang, J.H.2    Redmond, H.P.3
  • 30
    • 33645050400 scopus 로고    scopus 로고
    • HSV-1 infection induces the expression of proinflammatory cytokines, IFNs and TLR7 in human corneal epithelial cells
    • Li, H., J. Zhang, A. Kumar, M. Zheng, S. Atherton, and F. Yu. 2006. HSV-1 infection induces the expression of proinflammatory cytokines, IFNs and TLR7 in human corneal epithelial cells. Immunology 117:167-176.
    • (2006) Immunology , vol.117 , pp. 167-176
    • Li, H.1    Zhang, J.2    Kumar, A.3    Zheng, M.4    Atherton, S.5    Yu, F.6
  • 31
    • 0035881949 scopus 로고    scopus 로고
    • Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4
    • Medvedev, A. E., P. Henneke, A. Schromm, E. Lien, R. Ingalls, M. J. Fenton, D. T. Golenbock, and S. N. Vogel. 2001. Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4. J. Immunol. 167:2257-2267.
    • (2001) J. Immunol , vol.167 , pp. 2257-2267
    • Medvedev, A.E.1    Henneke, P.2    Schromm, A.3    Lien, E.4    Ingalls, R.5    Fenton, M.J.6    Golenbock, D.T.7    Vogel, S.N.8
  • 32
    • 0034043956 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and Toll-like receptor 2 and 4 gene expression
    • Medvedev, A. E., K. M. Kopydlowski, and S. N. Vogel. 2000. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and Toll-like receptor 2 and 4 gene expression. J. Immunol. 164:5564-5574.
    • (2000) J. Immunol , vol.164 , pp. 5564-5574
    • Medvedev, A.E.1    Kopydlowski, K.M.2    Vogel, S.N.3
  • 33
    • 0015878914 scopus 로고
    • Patterns of tolerance to endotoxin
    • Milner, K. C. 1973. Patterns of tolerance to endotoxin. J. Infect. Dis. 128(Suppl):237-245.
    • (1973) J. Infect. Dis , vol.128 , Issue.SUPPL. , pp. 237-245
    • Milner, K.C.1
  • 34
    • 0037151080 scopus 로고    scopus 로고
    • Gram-negative flagellin-induced self-tolerance is associated with a block in interleukin-1 receptor-associated kinase release from Toll-like receptor 5
    • Mizel, S. B., and J. A. Snipes. 2002. Gram-negative flagellin-induced self-tolerance is associated with a block in interleukin-1 receptor-associated kinase release from Toll-like receptor 5. J. Biol. Chem. 277:22414-22420.
    • (2002) J. Biol. Chem , vol.277 , pp. 22414-22420
    • Mizel, S.B.1    Snipes, J.A.2
  • 35
    • 20244384395 scopus 로고    scopus 로고
    • Cutting edge: Endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression
    • Nomura, F., S. Akashi, Y. Sakao, S. Sato, T. Kawai, M. Matsumoto, K. Nakanishi, M. Kimoto, K. Miyake, K. Takeda, and S. Akira. 2000. Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression. J. Immunol. 164:3476-3479.
    • (2000) J. Immunol , vol.164 , pp. 3476-3479
    • Nomura, F.1    Akashi, S.2    Sakao, Y.3    Sato, S.4    Kawai, T.5    Matsumoto, M.6    Nakanishi, K.7    Kimoto, M.8    Miyake, K.9    Takeda, K.10    Akira, S.11
  • 37
    • 0037189544 scopus 로고    scopus 로고
    • Monomeric recombinant MD-2 binds Toll-like receptor 4 tightly and confers lipopolysaccharide responsiveness
    • Re, F., and J. L. Strominger. 2002. Monomeric recombinant MD-2 binds Toll-like receptor 4 tightly and confers lipopolysaccharide responsiveness. J. Biol. Chem. 277:23427-23432.
    • (2002) J. Biol. Chem , vol.277 , pp. 23427-23432
    • Re, F.1    Strominger, J.L.2
  • 38
    • 0026730706 scopus 로고
    • Systemic and topical protection studies using Pseudomonas aeruginosa flagella in an ocular model of infection
    • Rudner, X. L., L. D. Hazlett, and R. S. Berk. 1992. Systemic and topical protection studies using Pseudomonas aeruginosa flagella in an ocular model of infection. Curr. Eye Res. 11:727-738.
    • (1992) Curr. Eye Res , vol.11 , pp. 727-738
    • Rudner, X.L.1    Hazlett, L.D.2    Berk, R.S.3
  • 39
    • 0018905247 scopus 로고
    • Enhanced phagocytosis and bactericidal activity of hepatic reticuloendothelial system during endotoxin tolerance
    • Ruggiero, G., A. Andreana, R. Utili, and D. Galante. 1980. Enhanced phagocytosis and bactericidal activity of hepatic reticuloendothelial system during endotoxin tolerance. Infect. Immun. 27:798-803.
    • (1980) Infect. Immun , vol.27 , pp. 798-803
    • Ruggiero, G.1    Andreana, A.2    Utili, R.3    Galante, D.4
  • 40
    • 33748077451 scopus 로고    scopus 로고
    • Staphylococcus aureus-induced corneal inflammation is dependent on Toll-like receptor 2 and myeloid differentiation factor 88
    • Sun, Y., A. G. Hise, C. M. Kalsow, and E. Pearlman. 2006. Staphylococcus aureus-induced corneal inflammation is dependent on Toll-like receptor 2 and myeloid differentiation factor 88. Infect. Immun. 74:5325-5332.
    • (2006) Infect. Immun , vol.74 , pp. 5325-5332
    • Sun, Y.1    Hise, A.G.2    Kalsow, C.M.3    Pearlman, E.4
  • 41
    • 4344691423 scopus 로고    scopus 로고
    • Caspase-1 inhibitor reduces severity of Pseudomonas aeruginosa keratitis in mice
    • Thakur, A., R. P. Barrett, J. A. Hobden, and L. D. Hazlett. 2004. Caspase-1 inhibitor reduces severity of Pseudomonas aeruginosa keratitis in mice. Investig. Ophthalmol. Vis. Sci. 45:3177-3184.
    • (2004) Investig. Ophthalmol. Vis. Sci , vol.45 , pp. 3177-3184
    • Thakur, A.1    Barrett, R.P.2    Hobden, J.A.3    Hazlett, L.D.4
  • 42
  • 46
    • 0036159842 scopus 로고    scopus 로고
    • Endotoxin tolerance: A review
    • West, M. A., and W. Heagy. 2002. Endotoxin tolerance: a review. Crit. Care Med. 30:S64-S73.
    • (2002) Crit. Care Med , vol.30
    • West, M.A.1    Heagy, W.2
  • 47
    • 0036234150 scopus 로고    scopus 로고
    • Indecision about corticosteroids for bacterial keratitis - an evidence-based update
    • Wilhelmus, K. R. 2002. Indecision about corticosteroids for bacterial keratitis - an evidence-based update. Ophthalmology 109:835-842.
    • (2002) Ophthalmology , vol.109 , pp. 835-842
    • Wilhelmus, K.R.1
  • 48
    • 34247260430 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa infection and inflammation during contact lens wear: A review
    • Willcox, M. D. 2007. Pseudomonas aeruginosa infection and inflammation during contact lens wear: a review. Optom. Vision Sci. 84:273-278.
    • (2007) Optom. Vision Sci , vol.84 , pp. 273-278
    • Willcox, M.D.1
  • 49
    • 0020314130 scopus 로고
    • Quantification of ocular inflammation: Evaluation of polymorphonuclear leucocyte infiltration by measuring myeloperoxidase activity
    • Williams, R. N., C. A. Paterson, K. E. Eakins, and P. Bhattacherjee. 1982. Quantification of ocular inflammation: evaluation of polymorphonuclear leucocyte infiltration by measuring myeloperoxidase activity. Curr. Eye Res. 2:465-470.
    • (1982) Curr. Eye Res , vol.2 , pp. 465-470
    • Williams, R.N.1    Paterson, C.A.2    Eakins, K.E.3    Bhattacherjee, P.4
  • 51
    • 0037438350 scopus 로고    scopus 로고
    • CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: Alterations in IL-1 receptor-associated kinase expression
    • Yeo, S. J., J. G. Yoon, S. C. Hong, and A. K. Yi. 2003. CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: alterations in IL-1 receptor-associated kinase expression. J. Immunol. 170:1052-1061.
    • (2003) J. Immunol , vol.170 , pp. 1052-1061
    • Yeo, S.J.1    Yoon, J.G.2    Hong, S.C.3    Yi, A.K.4
  • 53
    • 33745041499 scopus 로고    scopus 로고
    • Defending the epithelium
    • Zaslott, M. 2006. Defending the epithelium. Nat. Med. 12:607-608.
    • (2006) Nat. Med , vol.12 , pp. 607-608
    • Zaslott, M.1
  • 54
    • 33745145802 scopus 로고    scopus 로고
    • Inducing endogenous antimicrobial peptides to battle infections
    • Zasloff, M. 2006. Inducing endogenous antimicrobial peptides to battle infections. Proc. Natl. Acad. Sci. USA 103:8913-8914.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 8913-8914
    • Zasloff, M.1
  • 55
    • 23444431775 scopus 로고    scopus 로고
    • Inflammatory responses of corneal epithelial cells to Pseudomonas aeruginosa infection
    • Zhang, J., X. Y. Wu, and F. S. Yu. 2005. Inflammatory responses of corneal epithelial cells to Pseudomonas aeruginosa infection. Curr. Eye Res. 30:527-534.
    • (2005) Curr. Eye Res , vol.30 , pp. 527-534
    • Zhang, J.1    Wu, X.Y.2    Yu, F.S.3
  • 56
    • 0141653750 scopus 로고    scopus 로고
    • Toll-like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin
    • Zhang, J., K. Xu, B. Ambati, and F. S. Yu. 2003. Toll-like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin. Investig. Ophthalmol. Vis. Sci. 44:4247-4254.
    • (2003) Investig. Ophthalmol. Vis. Sci , vol.44 , pp. 4247-4254
    • Zhang, J.1    Xu, K.2    Ambati, B.3    Yu, F.S.4


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