메뉴 건너뛰기




Volumn 188, Issue 4, 2012, Pages 1884-1895

ExoS and ExoT ADP ribosyltransferase activities mediate pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival

Author keywords

[No Author keywords available]

Indexed keywords

CXCL2 CHEMOKINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

EID: 84863136696     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102148     Document Type: Article
Times cited : (84)

References (63)
  • 1
    • 0023816362 scopus 로고
    • Bacterial keratitis after penetrating keratoplasty
    • Al-Hazzaa, S. A., and K. F. Tabbara. 1988. Bacterial keratitis after penetrating keratoplasty. Ophthalmology 95: 1504-1508.
    • (1988) Ophthalmology , vol.95 , pp. 1504-1508
    • Al-Hazzaa, S.A.1    Tabbara, K.F.2
  • 3
    • 40449129810 scopus 로고    scopus 로고
    • Risk factors and causative organisms in microbial keratitis
    • Green, M., A. Apel, and F. Stapleton. 2008. Risk factors and causative organisms in microbial keratitis. Cornea 27: 22-27.
    • (2008) Cornea , vol.27 , pp. 22-27
    • Green, M.1    Apel, A.2    Stapleton, F.3
  • 4
    • 0034925204 scopus 로고    scopus 로고
    • Bacterial keratitis: A prospective clinical and microbiological study
    • DOI 10.1136/bjo.85.7.842
    • Schaefer, F., O. Bruttin, L. Zografos, and Y. Guex-Crosier. 2001. Bacterial keratitis: a prospective clinical and microbiological study. Br. J. Ophthalmol. 85: 842-847. (Pubitemid 32662086)
    • (2001) British Journal of Ophthalmology , vol.85 , Issue.7 , pp. 842-847
    • Schaefer, F.1    Bruttin, O.2    Zografos, L.3    Guex-Crosier, Y.4
  • 5
    • 34247260430 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa infection and inflammation during contact lens wear: A review
    • DOI 10.1097/OPX.0b013e3180439c3e, PII 0000632420070400000008
    • Willcox, M. D. 2007. Pseudomonas aeruginosa infection and inflammation during contact lens wear: a review. Optom. Vis. Sci. 84: 273-278. (Pubitemid 46624851)
    • (2007) Optometry and Vision Science , vol.84 , Issue.4 , pp. 273-278
    • Willcox, M.D.P.1
  • 6
    • 79956364926 scopus 로고    scopus 로고
    • Geographic variations in microbial keratitis: An analysis of the peer-reviewed literature
    • Shah, A., A. Sachdev, D. Coggon, and P. Hossain. 2011. Geographic variations in microbial keratitis: an analysis of the peer-reviewed literature. Br. J. Ophthalmol. 95: 762-767.
    • (2011) Br. J. Ophthalmol. , vol.95 , pp. 762-767
    • Shah, A.1    Sachdev, A.2    Coggon, D.3    Hossain, P.4
  • 8
    • 0034660146 scopus 로고    scopus 로고
    • Prolonged elevation of IL-1 in Pseudomonas aeruginosa ocular infection regulates macrophage-inflammatory protein-2 production, polymorphonuclear neutrophil persistence, and corneal perforation
    • Rudner, X. L., K. A. Kernacki, R. P. Barrett, and L. D. Hazlett. 2000. Prolonged elevation of IL-1 in Pseudomonas aeruginosa ocular infection regulates macrophage-inflammatory protein-2 production, polymorphonuclear neutrophil persistence, and corneal perforation. J. Immunol. 164: 6576-6582. (Pubitemid 30408844)
    • (2000) Journal of Immunology , vol.164 , Issue.12 , pp. 6576-6582
    • Rudner, X.L.1    Kernacki, K.A.2    Barrett, R.P.3    Hazlett, L.D.4
  • 10
    • 41949106689 scopus 로고    scopus 로고
    • Disruption of CFTR-dependent lipid rafts reduces bacterial levels and corneal disease in a murine model of Pseudomonas aeruginosa keratitis
    • Zaidi, T., M. Bajmoczi, T. Zaidi, D. E. Golan, and G. B. Pier. 2008. Disruption of CFTR-dependent lipid rafts reduces bacterial levels and corneal disease in a murine model of Pseudomonas aeruginosa keratitis. Invest. Ophthalmol. Vis. Sci. 49: 1000-1009.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 1000-1009
    • Zaidi, T.1    Bajmoczi, M.2    Zaidi, T.3    Golan, D.E.4    Pier, G.B.5
  • 11
    • 79959901231 scopus 로고    scopus 로고
    • Interferon-gamma-induced MD-2 protein expression and lipopolysaccharide (LPS) responsiveness in corneal epithelial cells is mediated by Janus tyrosine kinase-2 activation and direct binding of STAT1 protein to the MD-2 promoter
    • Roy, S., Y. Sun, and E. Pearlman. 2011. Interferon-gamma-induced MD-2 protein expression and lipopolysaccharide (LPS) responsiveness in corneal epithelial cells is mediated by Janus tyrosine kinase-2 activation and direct binding of STAT1 protein to the MD-2 promoter. J. Biol. Chem. 286: 23753-23762.
    • (2011) J. Biol. Chem. , vol.286 , pp. 23753-23762
    • Roy, S.1    Sun, Y.2    Pearlman, E.3
  • 12
    • 33750081757 scopus 로고    scopus 로고
    • The myeloid differentiation factor 88 is dispensable for the development of a delayed host response to Pseudomonas aeruginosa lung infection in mice
    • DOI 10.1111/j.1365-2249.2006.03210.x
    • Power, M. R., J. S. Marshall, M. Yamamoto, S. Akira, and T. J. Lin. 2006. The myeloid differentiation factor 88 is dispensable for the development of a delayed host response to Pseudomonas aeruginosa lung infection in mice. Clin. Exp. Immunol. 146: 323-329. (Pubitemid 44581348)
    • (2006) Clinical and Experimental Immunology , vol.146 , Issue.2 , pp. 323-329
    • Power, M.R.1    Marshall, J.S.2    Yamamoto, M.3    Akira, S.4    Lin, T.-J.5
  • 13
    • 10344254339 scopus 로고    scopus 로고
    • The development of early host response to Pseudomonas aeruginosa lung infection is critically dependent on myeloid differentiation factor 88 in mice
    • DOI 10.1074/jbc.M402111200
    • Power, M. R., Y. Peng, E. Maydanski, J. S. Marshall, and T. J. Lin. 2004. The development of early host response to Pseudomonas aeruginosa lung infection is critically dependent on myeloid differentiation factor 88 in mice. J. Biol. Chem. 279: 49315-49322. (Pubitemid 39625818)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.47 , pp. 49315-49322
    • Power, M.R.1    Peng, Y.2    Maydanski, E.3    Marshall, J.S.4    Lin, T.-J.5
  • 15
    • 72449194729 scopus 로고    scopus 로고
    • Inescapable need for neutrophils as mediators of cellular innate immunity to acute Pseudomonas aeruginosa pneumonia
    • Koh, A. Y., G. P. Priebe, C. Ray, N. Van Rooijen, and G. B. Pier. 2009. Inescapable need for neutrophils as mediators of cellular innate immunity to acute Pseudomonas aeruginosa pneumonia. Infect. Immun. 77: 5300-5310.
    • (2009) Infect. Immun. , vol.77 , pp. 5300-5310
    • Koh, A.Y.1    Priebe, G.P.2    Ray, C.3    Van Rooijen, N.4    Pier, G.B.5
  • 16
    • 69249157248 scopus 로고    scopus 로고
    • The type III secretion system of Pseudomonas aeruginosa: Infection by injection
    • Hauser, A. R. 2009. The type III secretion system of Pseudomonas aeruginosa: infection by injection. Nat. Rev. Microbiol. 7: 654-665.
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 654-665
    • Hauser, A.R.1
  • 17
    • 33845249292 scopus 로고    scopus 로고
    • Protein delivery into eukaryotic cells by type III secretion machines
    • DOI 10.1038/nature05272, PII NATURE05272
    • Galán, J. E., and H. Wolf-Watz. 2006. Protein delivery into eukaryotic cells by type III secretion machines. Nature 444: 567-573. (Pubitemid 44864429)
    • (2006) Nature , vol.444 , Issue.7119 , pp. 567-573
    • Galan, J.E.1    Wolf-Watz, H.2
  • 18
    • 4444342607 scopus 로고    scopus 로고
    • ExoU is a potent intracellular phospholipase
    • DOI 10.1111/j.1365-2958.2004.04194.x
    • Sato, H., and D. W. Frank. 2004. ExoU is a potent intracellular phospholipase. Mol. Microbiol. 53: 1279-1290. (Pubitemid 39209104)
    • (2004) Molecular Microbiology , vol.53 , Issue.5 , pp. 1279-1290
    • Sato, H.1    Frank, D.W.2
  • 20
    • 0742288077 scopus 로고    scopus 로고
    • Epithelial Cell Polarity Alters Rho-GTPase Responses to Pseudomonas aeruginosa
    • DOI 10.1091/mbc.E03-08-0559
    • Kazmierczak, B. I., K. Mostov, and J. N. Engel. 2004. Epithelial cell polarity alters Rho-GTPase responses to Pseudomonas aeruginosa. Mol. Biol. Cell 15: 411-419. (Pubitemid 38146461)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.2 , pp. 411-419
    • Kazmierczak, B.I.1    Mostov, K.2    Engel, J.N.3
  • 21
    • 0036137206 scopus 로고    scopus 로고
    • In vivo Rho GTPase-activating protein activity of Pseudomonas aeruginosa cytotoxin Exos
    • DOI 10.1128/IAI.70.1.360-367.2002
    • Krall, R., J. Sun, K. J. Pederson, and J. T. Barbieri. 2002. In vivo rho GTPase-activating protein activity of Pseudomonas aeruginosa cytotoxin ExoS. Infect. Immun. 70: 360-367. (Pubitemid 34028636)
    • (2002) Infection and Immunity , vol.70 , Issue.1 , pp. 360-367
    • Krall, R.1    Sun, J.2    Pederson, K.J.3    Barbieri, J.T.4
  • 22
    • 59849110833 scopus 로고    scopus 로고
    • Role of Pseudomonas aeruginosa type III effectors in disease
    • Engel, J., and P. Balachandran. 2009. Role of Pseudomonas aeruginosa type III effectors in disease. Curr. Opin. Microbiol. 12: 61-66.
    • (2009) Curr. Opin. Microbiol. , vol.12 , pp. 61-66
    • Engel, J.1    Balachandran, P.2
  • 23
    • 0034769748 scopus 로고    scopus 로고
    • Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa
    • Feltman, H., G. Schulert, S. Khan, M. Jain, L. Peterson, and A. R. Hauser. 2001. Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa. Microbiology 147: 2659-2669. (Pubitemid 32976307)
    • (2001) Microbiology , vol.147 , Issue.10 , pp. 2659-2669
    • Feltman, H.1    Schulert, G.2    Khan, S.3    Jain, M.4    Peterson, L.5    Hauser, A.R.6
  • 24
    • 0037363388 scopus 로고    scopus 로고
    • Phenotype of Pseudomonas aeruginosa isolates causing corneal infection between 1997 and 2000
    • DOI 10.1097/00003226-200303000-00010
    • Cowell, B. A., B. A. Weissman, K. K. Yeung, L. Johnson, S. Ho, R. Van, D. Bruckner, B. Mondino, and S. M. Fleiszig. 2003. Phenotype of Pseudomonas aeruginosa isolates causing corneal infection between 1997 and 2000. Cornea 22: 131-134. (Pubitemid 36701914)
    • (2003) Cornea , vol.22 , Issue.2 , pp. 131-134
    • Cowell, B.A.1    Weissman, B.A.2    Yeung, K.K.3    Johnson, L.4    Ho, S.5    Van, R.6    Bruckner, D.7    Mondino, B.8    Fleiszig, S.M.J.9
  • 25
    • 36448949057 scopus 로고    scopus 로고
    • Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity
    • DOI 10.1016/j.exer.2007.08.015, PII S0014483507002412
    • Tam, C., S. E. Lewis, W. Y. Li, E. Lee, D. J. Evans, and S. M. Fleiszig. 2007. Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity. Exp. Eye Res. 85: 799-805. (Pubitemid 350166366)
    • (2007) Experimental Eye Research , vol.85 , Issue.6 , pp. 799-805
    • Tam, C.1    Lewis, S.E.2    Li, W.Y.3    Lee, E.4    Evans, D.J.5    Fleiszig, S.M.J.6
  • 26
    • 0345275986 scopus 로고    scopus 로고
    • A comparison of invasive and cytotoxic Pseudomonas aeruginosa strain-induced corneal disease responses to therapeutics
    • DOI 10.1076/ceyr.27.5.289.17220
    • Lee, E. J., T. N. Truong, M. N. Mendoza, and S. M. Fleiszig. 2003. A comparison of invasive and cytotoxic Pseudomonas aeruginosa strain-induced corneal disease responses to therapeutics. Curr. Eye Res. 27: 289-299. (Pubitemid 37445266)
    • (2003) Current Eye Research , vol.27 , Issue.5 , pp. 289-299
    • Lee, E.J.1    Truong, T.N.2    Mendoza, M.N.3    Fleiszig, S.M.J.4
  • 27
    • 0345714620 scopus 로고    scopus 로고
    • Role of Pseudomonas aeruginosa ExsA in Penetration through Corneal Epithelium in a Novel In Vivo Model
    • DOI 10.1167/iovs.03-0229
    • Lee, E. J., D. J. Evans, and S. M. Fleiszig. 2003. Role of Pseudomonas aeruginosa ExsA in penetration through corneal epithelium in a novel in vivo model. Invest. Ophthalmol. Vis. Sci. 44: 5220-5227. (Pubitemid 37475392)
    • (2003) Investigative Ophthalmology and Visual Science , vol.44 , Issue.12 , pp. 5220-5227
    • Lee, E.J.1    Evans, D.J.2    Fleiszig, S.M.J.3
  • 28
    • 0041861176 scopus 로고    scopus 로고
    • Contribution of ExsA-regulated factors to corneal infection by cytotoxic and invasive Pseudomonas aeruginosa in a murine scarification model
    • DOI 10.1167/iovs.02-1302
    • Lee, E. J., B. A. Cowell, D. J. Evans, and S. M. Fleiszig. 2003. Contribution of ExsA-regulated factors to corneal infection by cytotoxic and invasive Pseudomonas aeruginosa in a murine scarification model. Invest. Ophthalmol. Vis. Sci. 44: 3892-3898. (Pubitemid 37047960)
    • (2003) Investigative Ophthalmology and Visual Science , vol.44 , Issue.9 , pp. 3892-3898
    • Lee, E.J.1    Cowell, B.A.2    Evans, D.J.3    Fleiszig, S.M.J.4
  • 29
    • 77950271943 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa cytotoxin ExoU is injected into phagocytic cells during acute pneumonia
    • Diaz, M. H., and A. R. Hauser. 2010. Pseudomonas aeruginosa cytotoxin ExoU is injected into phagocytic cells during acute pneumonia. Infect. Immun. 78: 1447-1456.
    • (2010) Infect. Immun. , vol.78 , pp. 1447-1456
    • Diaz, M.H.1    Hauser, A.R.2
  • 30
    • 15544389065 scopus 로고    scopus 로고
    • Role of the type III secreted exoenzymes S, T, and Y in systemic spread of Pseudomonas aeruginosa PAO1 in vivo
    • DOI 10.1128/IAI.73.3.1706-1713.2005
    • Vance, R. E., A. Rietsch, and J. J. Mekalanos. 2005. Role of the type III secreted exoenzymes S, T, and Y in systemic spread of Pseudomonas aeruginosa PAO1 in vivo. Infect. Immun. 73: 1706-1713. (Pubitemid 40470759)
    • (2005) Infection and Immunity , vol.73 , Issue.3 , pp. 1706-1713
    • Vance, R.E.1    Rietsch, A.2    Mekalanos, J.J.3
  • 33
    • 0034871821 scopus 로고    scopus 로고
    • Overexpression of the MexEF-OprN multidrug efflux system affects cell-to-cell signaling in Pseudomonas aeruginosa
    • DOI 10.1128/JB.183.18.5213-5222.2001
    • Köhler, T., C. van Delden, L. K. Curty, M. M. Hamzehpour, and J. C. Pechere. 2001. Overexpression of the MexEF-OprN multidrug efflux system affects cell-to-cell signaling in Pseudomonas aeruginosa. J. Bacteriol. 183: 5213-5222. (Pubitemid 32802590)
    • (2001) Journal of Bacteriology , vol.183 , Issue.18 , pp. 5213-5222
    • Kohler, T.1    Van Delden, C.2    Curty, L.K.3    Hamzehpour, M.M.4    Pechere, J.-C.5
  • 34
    • 1342344974 scopus 로고    scopus 로고
    • Effect of Metabolic Imbalance on Expression of Type III Secretion Genes in Pseudomonas aeruginosa
    • DOI 10.1128/IAI.72.3.1383-1390.2004
    • Rietsch, A., M. C. Wolfgang, and J. J. Mekalanos. 2004. Effect of metabolic imbalance on expression of type III secretion genes in Pseudomonas aeruginosa. Infect. Immun. 72: 1383-1390. (Pubitemid 38263759)
    • (2004) Infection and Immunity , vol.72 , Issue.3 , pp. 1383-1390
    • Rietsch, A.1    Wolfgang, M.C.2    Mekalanos, J.J.3
  • 35
    • 41949093141 scopus 로고    scopus 로고
    • ExoS controls the cell contact-mediated switch to effector secretion in Pseudomonas aeruginosa
    • DOI 10.1128/JB.01553-07
    • Cisz, M., P. C. Lee, and A. Rietsch. 2008. ExoS controls the cell contact-mediated switch to effector secretion in Pseudomonas aeruginosa. J. Bacteriol. 190: 2726-2738. (Pubitemid 351508173)
    • (2008) Journal of Bacteriology , vol.190 , Issue.8 , pp. 2726-2738
    • Cisz, M.1    Lee, P.-C.2    Rietsch, A.3
  • 36
    • 0041355556 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa ExoT ADP-ribosylates CT10 regulator of kinase (Crk) proteins
    • DOI 10.1074/jbc.M304290200
    • Sun, J., and J. T. Barbieri. 2003. Pseudomonas aeruginosa ExoT ADP-ribosylates CT10 regulator of kinase (Crk) proteins. J. Biol. Chem. 278: 32794-32800. (Pubitemid 37055720)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.35 , pp. 32794-32800
    • Sun, J.1    Barbieri, J.T.2
  • 37
    • 77957675910 scopus 로고    scopus 로고
    • Distinct roles for Dectin-1 and TLR4 in the pathogenesis of Aspergillus fumigatus keratitis
    • Leal, S. M., Jr., S. Cowden, Y. C. Hsia, M. A. Ghannoum, M. Momany, and E. Pearlman. 2010. Distinct roles for Dectin-1 and TLR4 in the pathogenesis of Aspergillus fumigatus keratitis. PLoS Pathog. 6: e1000976.
    • (2010) PLoS Pathog. , vol.6
    • Leal Jr., S.M.1    Cowden, S.2    Hsia, Y.C.3    Ghannoum, M.A.4    Momany, M.5    Pearlman, E.6
  • 39
    • 64849090438 scopus 로고    scopus 로고
    • Bone marrow chimeras and c-fms conditional ablation (Mafia) mice reveal an essential role for resident myeloid cells in lipopolysaccharide/TLR4-induced corneal inflammation
    • Chinnery, H. R., E. C. Carlson, Y. Sun, M. Lin, S. H. Burnett, V. L. Perez, P. G. McMenamin, and E. Pearlman. 2009. Bone marrow chimeras and c-fms conditional ablation (Mafia) mice reveal an essential role for resident myeloid cells in lipopolysaccharide/TLR4-induced corneal inflammation. J. Immunol. 182: 2738-2744.
    • (2009) J. Immunol. , vol.182 , pp. 2738-2744
    • Chinnery, H.R.1    Carlson, E.C.2    Sun, Y.3    Lin, M.4    Burnett, S.H.5    Perez, V.L.6    McMenamin, P.G.7    Pearlman, E.8
  • 41
    • 45949095358 scopus 로고    scopus 로고
    • Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide
    • DOI 10.1189/jlb.0108076
    • Sun, Y., T. Fox, G. Adhikary, M. Kester, and E. Pearlman. 2008. Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide. J. Leukoc. Biol. 83: 1512-1521. (Pubitemid 351960333)
    • (2008) Journal of Leukocyte Biology , vol.83 , Issue.6 , pp. 1512-1521
    • Sun, Y.1    Fox, T.2    Adhikary, G.3    Kester, M.4    Pearlman, E.5
  • 42
    • 33847780897 scopus 로고    scopus 로고
    • CXCL1/KC and CXCL5/LIX are selectively produced by corneal fibroblasts and mediate neutrophil infiltration to the corneal stroma in LPS keratitis
    • DOI 10.1189/jlb.0806502
    • Lin, M., E. Carlson, E. Diaconu, and E. Pearlman. 2007. CXCL1/KC and CXCL5/LIX are selectively produced by corneal fibroblasts and mediate neutrophil infiltration to the corneal stroma in LPS keratitis. J. Leukoc. Biol. 81: 786-792. (Pubitemid 46393556)
    • (2007) Journal of Leukocyte Biology , vol.81 , Issue.3 , pp. 786-792
    • Lin, M.1    Carlson, E.2    Diaconu, E.3    Pearlman, E.4
  • 43
    • 0035173475 scopus 로고    scopus 로고
    • Expression of ExsA in trans confers type III secretion system-dependent cytotoxicity on noncytotoxic Pseudomonas aeruginosa cystic fibrosis isolates
    • DOI 10.1128/IAI.69.1.538-542.2001
    • Dacheux, D., I. Attree, and B. Toussaint. 2001. Expression of ExsA in trans confers type III secretion system-dependent cytotoxicity on noncytotoxic Pseudomonas aeruginosa cystic fibrosis isolates. Infect. Immun. 69: 538-542. (Pubitemid 32038355)
    • (2001) Infection and Immunity , vol.69 , Issue.1 , pp. 538-542
    • Dacheux, D.1    Attree, I.2    Toussaint, B.3
  • 44
    • 33644825538 scopus 로고    scopus 로고
    • ExoS of Pseudomonas aeruginosa induces apoptosis through a Fas receptor/caspase 8-independent pathway in HeLa cells
    • DOI 10.1111/j.1462-5822.2005.00624.x
    • Alaoui-El-Azher, M., J. Jia, W. Lian, and S. Jin. 2006. ExoS of Pseudomonas aeruginosa induces apoptosis through a Fas receptor/caspase 8-independent pathway in HeLa cells. Cell. Microbiol. 8: 326-338. (Pubitemid 43356054)
    • (2006) Cellular Microbiology , vol.8 , Issue.2 , pp. 326-338
    • Alaoui-El-Azher, M.1    Jia, J.2    Lian, W.3    Jin, S.4
  • 45
    • 40749104951 scopus 로고    scopus 로고
    • The Pseudomonas aeruginosa type III secreted toxin ExoT is necessary and sufficient to induce apoptosis in epithelial cells
    • DOI 10.1111/j.1462-5822.2007.01102.x
    • Shafikhani, S. H., C. Morales, and J. Engel. 2008. The Pseudomonas aeruginosa type III secreted toxin ExoT is necessary and sufficient to induce apoptosis in epithelial cells. Cell. Microbiol. 10: 994-1007. (Pubitemid 351386952)
    • (2008) Cellular Microbiology , vol.10 , Issue.4 , pp. 994-1007
    • Shafikhani, S.H.1    Morales, C.2    Engel, J.3
  • 46
    • 35748966439 scopus 로고    scopus 로고
    • The ocular surface: The challenge to enable and protect vision. The Friedenwald lecture
    • DOI 10.1167/iovs.07-0770
    • Gipson, I. K. 2007. The ocular surface: the challenge to enable and protect vision: the Friedenwald lecture. Invest. Ophthalmol. Vis. Sci. 48: 4391-4398. (Pubitemid 351260950)
    • (2007) Investigative Ophthalmology and Visual Science , vol.48 , Issue.10 , pp. 4391-4398
    • Gipson, I.K.1
  • 47
    • 58149103363 scopus 로고    scopus 로고
    • The role of antimicrobial peptides at the ocular surface
    • McDermott, A. M. 2009. The role of antimicrobial peptides at the ocular surface. Ophthalmic Res. 41: 60-75.
    • (2009) Ophthalmic Res. , vol.41 , pp. 60-75
    • McDermott, A.M.1
  • 48
    • 79955930098 scopus 로고    scopus 로고
    • Factors impacting corneal epithelial barrier function against Pseudomonas aeruginosa traversal
    • Alarcon, I., C. Tam, J. J. Mun, J. LeDue, D. J. Evans, and S. M. Fleiszig. 2011. Factors impacting corneal epithelial barrier function against Pseudomonas aeruginosa traversal. Invest. Ophthalmol. Vis. Sci. 52: 1368-1377.
    • (2011) Invest. Ophthalmol. Vis. Sci. , vol.52 , pp. 1368-1377
    • Alarcon, I.1    Tam, C.2    Mun, J.J.3    LeDue, J.4    Evans, D.J.5    Fleiszig, S.M.6
  • 49
    • 69749112208 scopus 로고    scopus 로고
    • Increased resistance of contact lens-related bacterial biofilms to antimicrobial activity of soft contact lens care solutions
    • Szczotka-Flynn, L. B., Y. Imamura, J. Chandra, C. Yu, P. K. Mukherjee, E. Pearlman, and M. A. Ghannoum. 2009. Increased resistance of contact lens-related bacterial biofilms to antimicrobial activity of soft contact lens care solutions. Cornea 28: 918-926.
    • (2009) Cornea , vol.28 , pp. 918-926
    • Szczotka-Flynn, L.B.1    Imamura, Y.2    Chandra, J.3    Yu, C.4    Mukherjee, P.K.5    Pearlman, E.6    Ghannoum, M.A.7
  • 50
    • 77950682184 scopus 로고    scopus 로고
    • The impact of inoculation parameters on the pathogenesis of contact lens-related infectious keratitis
    • Tam, C., J. J. Mun, D. J. Evans, and S. M. Fleiszig. 2010. The impact of inoculation parameters on the pathogenesis of contact lens-related infectious keratitis. Invest. Ophthalmol. Vis. Sci. 51: 3100-3106.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , pp. 3100-3106
    • Tam, C.1    Mun, J.J.2    Evans, D.J.3    Fleiszig, S.M.4
  • 51
    • 42949147704 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa induces membrane blebs in epithelial cells, which are utilized as a niche for intracellular replication and motility
    • DOI 10.1128/IAI.01221-07
    • Angus, A. A., A. A. Lee, D. K. Augustin, E. J. Lee, D. J. Evans, and S. M. Fleiszig. 2008. Pseudomonas aeruginosa induces membrane blebs in epithelial cells, which are utilized as a niche for intracellular replication and motility. Infect. Immun. 76: 1992-2001. (Pubitemid 351656131)
    • (2008) Infection and Immunity , vol.76 , Issue.5 , pp. 1992-2001
    • Angus, A.A.1    Lee, A.A.2    Augustin, D.K.3    Lee, E.J.4    Evans, D.J.5    Fleiszig, S.M.J.6
  • 52
    • 78049431931 scopus 로고    scopus 로고
    • The ADP-ribosylation domain of Pseudomonas aeruginosa ExoS is required for membrane bleb niche formation and bacterial survival within epithelial cells
    • Angus, A. A., D. J. Evans, J. T. Barbieri, and S. M. Fleiszig. 2010. The ADP-ribosylation domain of Pseudomonas aeruginosa ExoS is required for membrane bleb niche formation and bacterial survival within epithelial cells. Infect. Immun. 78: 4500-4510.
    • (2010) Infect. Immun. , vol.78 , pp. 4500-4510
    • Angus, A.A.1    Evans, D.J.2    Barbieri, J.T.3    Fleiszig, S.M.4
  • 53
    • 33645550320 scopus 로고    scopus 로고
    • Exoenzyme S of Pseudomonas aeruginosa is not able to induce apoptosis when cells express activated proteins, such as Ras or protein kinase B/Akt
    • Jansson, A. L., L. Yasmin, P. Warne, J. Downward, R. H. Palmer, and B. Hallberg. 2006. Exoenzyme S of Pseudomonas aeruginosa is not able to induce apoptosis when cells express activated proteins, such as Ras or protein kinase B/Akt. Cell. Microbiol. 8: 815-822.
    • (2006) Cell. Microbiol. , vol.8 , pp. 815-822
    • Jansson, A.L.1    Yasmin, L.2    Warne, P.3    Downward, J.4    Palmer, R.H.5    Hallberg, B.6
  • 54
    • 0033753988 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa mediated apoptosis requires the ADP-ribosylating activity of exoS
    • Kaufman, M. R., J. Jia, L. Zeng, U. Ha, M. Chow, and S. Jin. 2000. Pseudomonas aeruginosa mediated apoptosis requires the ADP-ribosylating activity of exoS. Microbiology 146: 2531-2541.
    • (2000) Microbiology , vol.146 , pp. 2531-2541
    • Kaufman, M.R.1    Jia, J.2    Zeng, L.3    Ha, U.4    Chow, M.5    Jin, S.6
  • 55
    • 15544380187 scopus 로고    scopus 로고
    • Activities of Pseudomonas aeruginosa effectors secreted by the type III secretion system in vitro and during infection
    • DOI 10.1128/IAI.73.3.1695-1705.2005
    • Lee, V. T., R. S. Smith, B. Tümmler, and S. Lory. 2005. Activities of Pseudomonas aeruginosa effectors secreted by the type III secretion system in vitro and during infection. Infect. Immun. 73: 1695-1705. (Pubitemid 40470758)
    • (2005) Infection and Immunity , vol.73 , Issue.3 , pp. 1695-1705
    • Lee, V.T.1    Smith, R.S.2    Tummler, B.3    Lory, S.4
  • 56
    • 67651229410 scopus 로고    scopus 로고
    • Role of the corneal epithelial basement membrane in ocular defense against Pseudomonas aeruginosa
    • Alarcon, I., L. Kwan, C. Yu, D. J. Evans, and S. M. Fleiszig. 2009. Role of the corneal epithelial basement membrane in ocular defense against Pseudomonas aeruginosa. Infect. Immun. 77: 3264-3271.
    • (2009) Infect. Immun. , vol.77 , pp. 3264-3271
    • Alarcon, I.1    Kwan, L.2    Yu, C.3    Evans, D.J.4    Fleiszig, S.M.5
  • 58
    • 9244236027 scopus 로고    scopus 로고
    • Relative contributions of Pseudomonas aeruginosa ExoU, ExoS, and ExoT to virulence in the lung
    • DOI 10.1128/IAI.72.12.6969-6977.2004
    • Shaver, C. M., and A. R. Hauser. 2004. Relative contributions of Pseudomonas aeruginosa ExoU, ExoS, and ExoT to virulence in the lung. Infect. Immun. 72: 6969-6977. (Pubitemid 39552365)
    • (2004) Infection and Immunity , vol.72 , Issue.12 , pp. 6969-6977
    • Shaver, C.M.1    Hauser, A.R.2
  • 59
    • 30744443237 scopus 로고    scopus 로고
    • Interactions between effector proteins of the Pseudomonas aeruginosa type III secretion system do not significantly affect several measures of disease severity in mammals
    • DOI 10.1099/mic.0.28368-0
    • Shaver, C. M., and A. R. Hauser. 2006. Interactions between effector proteins of the Pseudomonas aeruginosa type III secretion system do not significantly affect several measures of disease severity in mammals. Microbiology 152: 143-152. (Pubitemid 43092402)
    • (2006) Microbiology , vol.152 , Issue.1 , pp. 143-152
    • Shaver, C.M.1    Hauser, A.R.2
  • 62
    • 18944375457 scopus 로고    scopus 로고
    • Quorum sensing negatively controls type III secretion regulon expression in Pseudomonas aeruginosa PAO1
    • DOI 10.1128/JB.187.11.3898-3902.2005
    • Bleves, S., C. Soscia, P. Nogueira-Orlandi, A. Lazdunski, and A. Filloux. 2005. Quorum sensing negatively controls type III secretion regulon expression in Pseudomonas aeruginosa PAO1. J. Bacteriol. 187: 3898-3902. (Pubitemid 40705600)
    • (2005) Journal of Bacteriology , vol.187 , Issue.11 , pp. 3898-3902
    • Bleves, S.1    Soscia, C.2    Nogueira-Orlandi, P.3    Lazdunski, A.4    Filloux, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.