Distinct roles for Dectin-1 and TLR4 in the pathogenesis of Aspergillus fumigatus keratitis

PLoS Pathogens

Volumn 6, Issue 7, 2010, Pages 1-16

  Leal Jr , Sixto M ^a,b   Cowden, Susan ^c   Hsia, Yen Cheng ^a   Ghannoum, Mahmoud A ^b   Momany, Michelle ^c   Pearlman, Eric ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCAN; CXCL1 CHEMOKINE; DECTIN 1; INTERLEUKIN 1BETA; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN KINASE SYK; RED FLUORESCENT PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; CXCL1 PROTEIN, MOUSE; LECTIN; MEMBRANE PROTEIN; NERVE PROTEIN; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPERGILLUS FUMIGATUS; CELL INFILTRATION; CLEARANCE; CONIDIUM; CONTROLLED STUDY; CORNEA STROMA; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE COURSE; DISEASE MODEL; FUNGUS GROWTH; FUNGUS HYPHAE; GENE EXPRESSION; GERMINATION; KERATOMYCOSIS; MACROPHAGE; MONONUCLEAR CELL; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SURVIVAL; UPREGULATION; ANIMAL; BIOSYNTHESIS; GROWTH, DEVELOPMENT AND AGING; KERATITIS; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY;

ASPERGILLUS; ASPERGILLUS FUMIGATUS; MURINAE; MUS;

ANIMALS; ASPERGILLUS FUMIGATUS; BETA-GLUCANS; CHEMOKINE CXCL1; CORNEAL STROMA; INTERLEUKIN-1BETA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATITIS; LECTINS, C-TYPE; MACROPHAGES; MEMBRANE PROTEINS; MICE; NERVE TISSUE PROTEINS; PROTEIN-TYROSINE KINASES; TOLL-LIKE RECEPTOR 4;

EID: 77957675910     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000976     Document Type: Article

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