MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin

Journal of Pathology

Volumn 225, Issue 1, 2011, Pages 43-53

  Ferracin, Manuela ^a   Pedriali, Massimo ^a   Veronese, Angelo ^a,b   Zagatti, Barbara ^a   Gafà, Roberta ^a   Magri, Eros ^a   Lunardi, Maria ^a   Munerato, Gardenia ^a   Querzoli, Giulia ^a   Maestri, Iva ^a   Ulazzi, Linda ^a   Nenci, Italo ^a   Croce, Carlo M ^b   Lanza, Giovanni ^a   Querzoli, Patrizia ^a   Negrini, Massimo ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

cancer with unknown primary; metastasis; microarray; microRNA

Indexed keywords

MICRORNA; PARAFFIN;

ARTICLE; CANCER DIAGNOSIS; CANCER OF UNKNOWN PRIMARY SITE; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; METASTASIS; MICROARRAY ANALYSIS; PREDICTION; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; CLUSTER ANALYSIS; FEMALE; FIXATIVES; FORMALDEHYDE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICRORNAS; MIDDLE AGED; NEOPLASMS, UNKNOWN PRIMARY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARAFFIN EMBEDDING; RNA, NEOPLASM;

EID: 79960905671     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2915     Document Type: Article

References (34)

1. Briasoulis E, Tolis C, Bergh J, et al., ESMO Minimum Clinical Recommendations for diagnosis, treatment and follow-up of cancers of unknown primary site (CUP). Ann Oncol 2005; 16 (Suppl 1): i75-i76. (Pubitemid 40872998)
2. Oien KA,. Pathologic evaluation of unknown primary cancer. Sem Oncol 2009; 36: 8-37.
3. Pavlidis N, Fizazi K,. Cancer of unknown primary (CUP). Crit Rev Oncol Hematol 2005; 54: 243-250. (Pubitemid 40693686)
4. Freudenberg LS, Rosenbaum-Krumme SJ, Bockisch A, et al., Cancer of unknown primary. Recent Results Cancer Res 2008; 170: 193-202.
5. Varadhachary GR, Abbruzzese JL, Lenzi R,. Diagnostic strategies for unknown primary cancer. Cancer 2004; 100: 1776-1785. (Pubitemid 38529553)
6. Pavlidis N, Briasoulis E, Hainsworth J, et al., Diagnostic and therapeutic management of cancer of an unknown primary. Eur J Cancer 2003; 39: 1990-2005. (Pubitemid 37297755)
7. Levi F, Te VC, Erler G, et al., Epidemiology of unknown primary tumours. Eur J Cancer 2002; 38: 1810-1812.
8. Pentheroudakis G, Briasoulis E, Pavlidis N,. Cancer of unknown primary site: missing primary or missing biology? Oncologist 2007; 12: 418-425. (Pubitemid 46698719)
9. Pentheroudakis G, Golfinopoulos V, Pavlidis N,. Switching benchmarks in cancer of unknown primary: from autopsy to microarray. Eur J Cancer 2007; 43: 2026-2036. (Pubitemid 47380362)
10. Ayoub JP, Hess KR, Abbruzzese MC, et al., Unknown primary tumors metastatic to liver. J Clin Oncol 1998; 16: 2105-2112. (Pubitemid 28265047)
11. van de Wouw AJ, Janssen-Heijnen ML, Coebergh JW, et al., Epidemiology of unknown primary tumours; incidence and population-based survival of 1285 patients in Southeast Netherlands, 1984-1992. Eur J Cancer 2002; 38: 409-413. (Pubitemid 34121969)
12. Huebner G, Link H, Kohne CH, et al., Paclitaxel and carboplatin vs gemcitabine and vinorelbine in patients with adeno- or undifferentiated carcinoma of unknown primary: a randomised prospective phase II trial. Br J Cancer 2009; 100: 44-49.
13. Abbruzzese JL, Abbruzzese MC, Lenzi R, et al., Analysis of a diagnostic strategy for patients with suspected tumors of unknown origin. J Clin Oncol 1995; 13: 2094-2103.
14. Bishop JF, Tracey E, Glass P, et al., Prognosis of sub-types of cancer of unknown primary (CUP) compared to metastatic cancer. J Clin Oncol 2007; 25: 21010.
15. Ferracin M, Veronese A, Negrini M,. Micromarkers: miRNAs in cancer diagnosis and prognosis. Expert Rev Mol Diagn 2010; 10: 297-308.
16. Farazi TA, Spitzer JI, Morozov P, et al., miRNAs in human cancer. J Pathol 2011; 223: 102-115.
17. Baffa R, Fassan M, Volinia S, et al., MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets. J Pathol 2009; 219: 214-221.
18. Monzon FA, Koen TJ,. Diagnosis of metastatic neoplasms: molecular approaches for identification of tissue of origin. Arch Pathol Lab Med 2010; 134: 216-224.
19. Rosenfeld N, Aharonov R, Meiri E, et al., MicroRNAs accurately identify cancer tissue origin. Nature Biotechnol 2008; 26: 462-469. (Pubitemid 351501813)
20. Jemal A, Siegel R, Ward E, et al., Cancer statistics, 2009. CA Cancer J Clin 2009; 59: 225-249.
21. Dennis JL, Hvidsten TR, Wit EC, et al., Markers of adenocarcinoma characteristic of the site of origin: development of a diagnostic algorithm. Clin Cancer Res 2005; 11: 3766-3772. (Pubitemid 40685594)
22. Volinia S, Calin GA, Liu CG, et al., A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 2006; 103: 2257-2261. (Pubitemid 43271657)
23. Tibshirani R, Hastie T, Narasimhan B, et al., Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc Natl Acad Sci U S A 2002; 99: 6567-6572. (Pubitemid 34526173)
24. Dumur CI, Lyons-Weiler M, Sciulli C, et al., Interlaboratory performance of a microarray-based gene expression test to determine tissue of origin in poorly differentiated and undifferentiated cancers. J Mol Diagn 2008; 10: 67-77. (Pubitemid 351184837)
25. Monzon FA, Lyons-Weiler M, Buturovic LJ, et al., Multicenter validation of a 1,550-gene expression profile for identification of tumor tissue of origin. J Clin Oncol 2009; 27: 2503-2508.
26. Bridgewater J, van Laar R, Floore A, et al., Gene expression profiling may improve diagnosis in patients with carcinoma of unknown primary. Br J Cancer 2008; 98: 1425-1430. (Pubitemid 351543580)
27. Horlings HM, van Laar RK, Kerst JM, et al., Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary. J Clin Oncol 2008; 26: 4435-4441.
28. Ma XJ, Patel R, Wang X, et al., Molecular classification of human cancers using a 92-gene real-time quantitative polymerase chain reaction assay. Arch Pathol Lab Med 2006; 130: 465-473.
29. Rosenwald S, Gilad S, Benjamin S, et al., Validation of a microRNA-based qRT-PCR test for accurate identification of tumor tissue origin. Mod Pathol 2010; 23: 814-823.
30. Talantov D, Baden J, Jatkoe T, et al., A quantitative reverse transcriptase-polymerase chain reaction assay to identify metastatic carcinoma tissue of origin. J Mol Diagn 2006; 8: 320-329. (Pubitemid 44063808)
31. Varadhachary GR, Raber MN, Matamoros A, et al., Carcinoma of unknown primary with a colon-cancer profile-changing paradigm and emerging definitions. Lancet Oncol 2008; 9: 596-599. (Pubitemid 351722584)
32. Varadhachary GR, Talantov D, Raber MN, et al., Molecular profiling of carcinoma of unknown primary and correlation with clinical evaluation. J Clin Oncol 2008; 26: 4442-4448.
33. Pimiento JM, Teso D, Malkan A, et al., Cancer of unknown primary origin: a decade of experience in a community-based hospital. Am J Surg 2007; 194: 833-837; discussion 837-838.
34. Varadhachary GR, Greco FA,. Overview of patient management and future directions in unknown primary carcinoma. Semin Oncol 2009; 36: 75-80.