-
1
-
-
0037230328
-
Outsourcing in the brain: Do neurons depend on cholesterol delivery by astrocytes?
-
Pfrieger FW (2003) Outsourcing in the brain: Do neurons depend on cholesterol delivery by astrocytes? Bioessays 25, 72-78.
-
(2003)
Bioessays
, vol.25
, pp. 72-78
-
-
Pfrieger, F.W.1
-
2
-
-
2442557294
-
Brain cholesterol: Long secret life behind a barrier
-
Bjorkhem I, Meaney S (2004) Brain cholesterol: Long secret life behind a barrier. Arterioscler Thromb Vasc Biol 24, 806-815.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 806-815
-
-
Bjorkhem, I.1
Meaney, S.2
-
3
-
-
0036916491
-
On the rate of translocatio in vitro and kinetics in vivo of the major oxysterols in human circulation: Critical importance of the position of the oxygen function
-
Meaney S, Bodin K, Diczfalusy U, Bjorkhem I (2002) On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: Critical importance of the position of the oxygen function. J Lipid Res 43, 2130-2135.
-
(2002)
J Lipid Res
, vol.43
, pp. 2130-2135
-
-
Meaney, S.1
Bodin, K.2
Diczfalusy, U.3
Bjorkhem, I.4
-
4
-
-
0029835410
-
Cholesterol homeostasis in human brain: Evidence for an age-dependent flux of 24Shydroxycholesterol from the brain into the circulation
-
Lutjohann D, Breuer O, Ahlborg G, Nennesmo I, Siden A, Diczfalusy U, Bjorkhem I (1996) Cholesterol homeostasis in human brain: Evidence for an age-dependent flux of 24Shydroxycholesterol from the brain into the circulation. Proc Natl Acad Sci U S A 93, 9799-9804.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9799-9804
-
-
Lutjohann, D.1
Breuer, O.2
Ahlborg, G.3
Nennesmo, I.4
Siden, A.5
Diczfalusy, U.6
Bjorkhem, I.7
-
5
-
-
0031848338
-
Cholesterol homeostasis in human brain: Turnover of 24S- hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation
-
Bjorkhem I, Lutjohann D, Diczfalusy U, Stahle L, Ahlborg G,Wahren J (1998) Cholesterol homeostasis in human brain: Turnover of 24S- hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation. J Lipid Res 39, 1594-1600.
-
(1998)
J Lipid Res
, vol.39
, pp. 1594-1600
-
-
Bjorkhem, I.1
Lutjohann, D.2
Diczfalusy, U.3
Stahle, L.4
Ahlborg, G.5
Wahren, J.6
-
6
-
-
39749104095
-
Role of ATP-binding cassette transporters in brain lipid transport and neurological disease
-
Kim WS,Weickert CS, Garner B (2008) Role of ATP-binding cassette transporters in brain lipid transport and neurological disease. J Neurochem 104, 1145-1166.
-
(2008)
J Neurochem
, vol.104
, pp. 1145-1166
-
-
Kim, W.S.1
Weickert, C.S.2
Garner, B.3
-
7
-
-
85047684678
-
Regulation of cholesterol homeostasis by the liver X receptors in the central nervous system
-
Whitney KD, Watson MA, Collins JL, Benson WG, Stone TM, Numerick MJ, Tippin TK, Wilson JG, Winegar DA, Kliewer SA (2002) Regulation of cholesterol homeostasis by the liver X receptors in the central nervous system. Mol Endocrinol 16, 1378-1385.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 1378-1385
-
-
Whitney, K.D.1
Watson, M.A.2
Collins, J.L.3
Benson, W.G.4
Stone, T.M.5
Numerick, M.J.6
Tippin, T.K.7
Wilson, J.G.8
Winegar, D.A.9
Kliewer, S.A.10
-
8
-
-
33744948883
-
24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux
-
Abildayeva K, Jansen PJ, Hirsch-Reinshagen V, Bloks VW, BakkerAH,Ramaekers FC, deVente J, GroenAK,Wellington CL, Kuipers F, Mulder M (2006) 24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux. J Biol Chem 281, 12799-12808.
-
(2006)
J Biol Chem
, vol.281
, pp. 12799-12808
-
-
Abildayeva, K.1
Jansen, P.J.2
Hirsch-Reinshagen, V.3
Bloks, V.W.4
Bakker, A.H.5
Ramaekers, F.C.6
Devente, J.7
Groen, A.K.8
Wellington, C.L.9
Kuipers, F.10
Mulder, M.11
-
9
-
-
33645237578
-
Expression of ABCG1, but not ABCA1, correlates with cholesterol release by cerebellar astroglia
-
Karten B, Campenot RB, Vance DE, Vance JE (2006) Expression of ABCG1, but not ABCA1, correlates with cholesterol release by cerebellar astroglia. J Biol Chem 281, 4049-4057.
-
(2006)
J Biol Chem
, vol.281
, pp. 4049-4057
-
-
Karten, B.1
Campenot, R.B.2
Vance, D.E.3
Vance, J.E.4
-
10
-
-
81255185004
-
Liver X receptors regulate cholesterol homeostasis in oligodendrocytes
-
Nelissen K, Mulder M, Smets I, Timmermans S, Smeets K, Ameloot M, Hendriks JJ (2012) Liver X receptors regulate cholesterol homeostasis in oligodendrocytes. J Neurosci Res 90, 60-71.
-
(2012)
J Neurosci Res
, vol.90
, pp. 60-71
-
-
Nelissen, K.1
Mulder, M.2
Smets, I.3
Timmermans, S.4
Smeets, K.5
Ameloot, M.6
Hendriks, J.J.7
-
11
-
-
34047250984
-
Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein e discs and suppression of amyloidbeta peptide generation
-
Kim WS, Rahmanto AS, Kamili A, Rye KA, Guillemin GJ, Gelissen IC, Jessup W, Hill AF, Garner B (2007) Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloidbeta peptide generation. J Biol Chem 282, 2851-2861.
-
(2007)
J Biol Chem
, vol.282
, pp. 2851-2861
-
-
Kim, W.S.1
Rahmanto, A.S.2
Kamili, A.3
Rye, K.A.4
Guillemin, G.J.5
Gelissen, I.C.6
Jessup, W.7
Hill, A.F.8
Garner, B.9
-
12
-
-
34547582862
-
Regulation of central nervous system cholesterol homeostasis by the liver X receptor agonist TO-901317
-
Eckert GP, Vardanian L, Rebeck GW, Burns MP (2007) Regulation of central nervous system cholesterol homeostasis by the liver X receptor agonist TO-901317. Neurosci Lett 423, 47-52.
-
(2007)
Neurosci Lett
, vol.423
, pp. 47-52
-
-
Eckert, G.P.1
Vardanian, L.2
Rebeck, G.W.3
Burns, M.P.4
-
13
-
-
33846827336
-
24S-hydroxycholesterol induces cholesterol release from choroid plexus epithelial cells in an apical-and apoE isoform-dependent manner concomitantly with the induction of ABCA1 and ABCG1 expression
-
Fujiyoshi M, Ohtsuki S, Hori S, Tachikawa M, Terasaki T (2007) 24S-hydroxycholesterol induces cholesterol release from choroid plexus epithelial cells in an apical-and apoE isoform-dependent manner concomitantly with the induction of ABCA1 and ABCG1 expression. J Neurochem 100, 968-978.
-
(2007)
J Neurochem
, vol.100
, pp. 968-978
-
-
Fujiyoshi, M.1
Ohtsuki, S.2
Hori, S.3
Tachikawa, M.4
Terasaki, T.5
-
14
-
-
79956311751
-
Critical role of astroglial apolipoprotein e and liver X receptor {alpha} Expression for microglial A{beta} phagocytosis
-
Terwel D, Steffensen KR, Verghese PB, Kummer MP, Gustafsson JA, Holtzman DM, Heneka MT (2011) Critical role of astroglial apolipoprotein E and liver X receptor-{alpha} Expression for microglial A{beta} phagocytosis. J Neurosci 31, 7049-7059.
-
(2011)
J Neurosci
, vol.31
, pp. 7049-7059
-
-
Terwel, D.1
Steffensen, K.R.2
Verghese, P.B.3
Kummer, M.P.4
Gustafsson, J.A.5
Holtzman, D.M.6
Heneka, M.T.7
-
15
-
-
14244255485
-
The liver X receptor ligand T0901317 decreases amyloid beta productio in vitro and in a mouse model of Alzheimer's disease
-
Koldamova RP, Lefterov IM, Staufenbiel M,Wolfe D, Huang S, Glorioso JC,Walter M, Roth MG, Lazo JS (2005) The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease. J Biol Chem 280, 4079-4088.
-
(2005)
J Biol Chem
, vol.280
, pp. 4079-4088
-
-
Koldamova, R.P.1
Lefterov, I.M.2
Staufenbiel, M.3
Wolfe, D.4
Huang, S.5
Glorioso, J.C.6
Walter, M.7
Roth, M.G.8
Lazo, J.S.9
-
16
-
-
33947610707
-
The LXR agonist TO901317 selectively lowers hippocampal Abeta42 and improves memory in the Tg2576 mouse model of Alzheimer's disease
-
Riddell DR, Zhou H, Comery TA, Kouranova E, Lo CF,Warwick HK, Ring RH, Kirksey Y, Aschmies S, Xu J, Kubek K, Hirst WD, Gonzales C, Chen Y, Murphy E, Leonard S, Vasylyev D, Oganesian A, Martone RL, Pangalos MN, Reinhart PH, Jacobsen JS (2007) The LXR agonist TO901317 selectively lowers hippocampal Abeta42 and improves memory in the Tg2576 mouse model of Alzheimer's disease. Mol Cell Neurosci 34, 621-628.
-
(2007)
Mol Cell Neurosci
, vol.34
, pp. 621-628
-
-
Riddell, D.R.1
Zhou, H.2
Comery, T.A.3
Kouranova, E.4
Lo, C.F.5
Warwick, H.K.6
Ring, R.H.7
Kirksey, Y.8
Aschmies, S.9
Xu, J.10
Kubek, K.11
Hirst, W.D.12
Gonzales, C.13
Chen, Y.14
Murphy, E.15
Leonard, S.16
Vasylyev, D.17
Oganesian, A.18
Martone, R.L.19
Pangalos, M.N.20
Reinhart, P.H.21
Jacobsen, J.S.22
more..
-
17
-
-
33745880391
-
The effects of ABCA1 on cholesterol efflux and Abeta level In Vitro and in Vivo
-
Burns MP, Vardanian L, Pajoohesh-Ganji A,Wang L, Cooper M, Harris DC, Duff K, Rebeck GW (2006) The effects of ABCA1 on cholesterol efflux and Abeta levels in vitro and in vivo. J Neurochem 98, 792-800.
-
(2006)
J Neurochem
, vol.98
, pp. 792-800
-
-
Burns, M.P.1
Vardanian, L.2
Pajoohesh-Ganji, A.3
Wang, L.4
Cooper, M.5
Harris, D.C.6
Duff, K.7
Rebeck, G.W.8
-
18
-
-
77958594257
-
ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice
-
Donkin JJ, Stukas S, Hirsch-Reinshagen V, Namjoshi D, Wilkinson A, May S, Chan J, Fan J, Collins J, Wellington CL (2010) ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice. J Biol Chem 285, 34144-34154.
-
(2010)
J Biol Chem
, vol.285
, pp. 34144-34154
-
-
Donkin, J.J.1
Stukas, S.2
Hirsch-Reinshagen, V.3
Namjoshi, D.4
Wilkinson, A.5
May, S.6
Chan, J.7
Fan, J.8
Collins, J.9
Wellington, C.L.10
-
19
-
-
77952630395
-
Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice
-
Fitz NF, Cronican A, Pham T, Fogg A, Fauq AH, Chapman R, Lefterov I, Koldamova R (2010) Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice. J Neurosci 30, 6862-6872.
-
(2010)
J Neurosci
, vol.30
, pp. 6862-6872
-
-
Fitz, N.F.1
Cronican, A.2
Pham, T.3
Fogg, A.4
Fauq, A.H.5
Chapman, R.6
Lefterov, I.7
Koldamova, R.8
-
20
-
-
34547531201
-
Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors
-
Zelcer N, Khanlou N, Clare R, Jiang Q, Reed-Geaghan EG, Landreth GE, Vinters HV, Tontonoz P (2007) Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors. Proc Natl Acad Sci U S A 104, 10601-10606.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 10601-10606
-
-
Zelcer, N.1
Khanlou, N.2
Clare, R.3
Jiang, Q.4
Reed-Geaghan, E.G.5
Landreth, G.E.6
Vinters, H.V.7
Tontonoz, P.8
-
21
-
-
84857412491
-
Direct evidence of abca1-mediated efflux of cholesterol at the mouse blood-brain barrier
-
Do TM, Ouellet M, Calon F, Chimini G, Chacun H, Farinotti R, Bourasset F (2011) Direct evidence of abca1-mediated efflux of cholesterol at the mouse blood-brain barrier. Mol Cell Biochem 357, 397-404.
-
(2011)
Mol Cell Biochem
, vol.357
, pp. 397-404
-
-
Do, T.M.1
Ouellet, M.2
Calon, F.3
Chimini, G.4
Chacun, H.5
Farinotti, R.6
Bourasset, F.7
-
22
-
-
63849221643
-
Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function
-
Karasinska JM, Rinninger F, Lutjohann D, Ruddle P, Franciosi S, Kruit JK, Singaraja RR, Hirsch-Reinshagen V, Fan J, Brunham LR, Bissada N, Ramakrishnan R, Wellington CL, Parks JS, Hayden MR (2009) Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function. J Neurosci 29, 3579-3589.
-
(2009)
J Neurosci
, vol.29
, pp. 3579-3589
-
-
Karasinska, J.M.1
Rinninger, F.2
Lutjohann, D.3
Ruddle, P.4
Franciosi, S.5
Kruit, J.K.6
Singaraja, R.R.7
Hirsch-Reinshagen, V.8
Fan, J.9
Brunham, L.R.10
Bissada, N.11
Ramakrishnan, R.12
Wellington, C.L.13
Parks, J.S.14
Hayden, M.R.15
-
23
-
-
81855168382
-
Processing of endogenous A-PP in blood-brain barrier endothelial cells is modulated by liver-x receptor agonists and altered cellular cholesterol homeostasis
-
Schweinzer C, Kober A, Lang I, Etschmaier K, Scholler M, Kresse A, Sattler W, Panzenboeck U (2011) Processing of endogenous A-PP in blood-brain barrier endothelial cells is modulated by liver-x receptor agonists and altered cellular cholesterol homeostasis. J Alzheimers Dis 27, 341-360.
-
(2011)
J Alzheimers Dis
, vol.27
, pp. 341-360
-
-
Schweinzer, C.1
Kober, A.2
Lang, I.3
Etschmaier, K.4
Scholler, M.5
Kresse, A.6
Sattler, W.7
Panzenboeck, U.8
-
24
-
-
38149090292
-
The blood-brain barrier in health and chronic neurodegenerative disorders
-
Zlokovic BV (2008) The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 57, 178-201.
-
(2008)
Neuron
, vol.57
, pp. 178-201
-
-
Zlokovic, B.V.1
-
25
-
-
78649487239
-
Pericytes are required for blood-brain barrier integrity during embryogenesis
-
Daneman R, Zhou L, Kebede AA, Barres BA (2010) Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature 468, 562-566.
-
(2010)
Nature
, vol.468
, pp. 562-566
-
-
Daneman, R.1
Zhou, L.2
Kebede, A.A.3
Barres, B.A.4
-
26
-
-
79961230399
-
Pericytes: Developmental, physiological, and pathological perspectives, problems, and promises
-
Armulik A, Genove G, Betsholtz C (2011) Pericytes: Developmental, physiological, and pathological perspectives, problems, and promises. Dev Cell 21, 193-215.
-
(2011)
Dev Cell
, vol.21
, pp. 193-215
-
-
Armulik, A.1
Genove, G.2
Betsholtz, C.3
-
27
-
-
58149131290
-
Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood-brain barrier: Use of a in vitro model
-
Gosselet F, Candela P, Sevin E, Berezowski V, Cecchelli R, Fenart L (2009) Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood-brain barrier: Use of an in vitro model. Brain Res 1249, 34-42.
-
(2009)
Brain Res
, vol.1249
, pp. 34-42
-
-
Gosselet, F.1
Candela, P.2
Sevin, E.3
Berezowski, V.4
Cecchelli, R.5
Fenart, L.6
-
28
-
-
0037044840
-
ABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at a in vitro blood-brain barrier constituted of porcine brain capillary endothelial cells
-
Panzenboeck U, Balazs Z, Sovic A, Hrzenjak A, Levak-Frank S, Wintersperger A, Malle E, Sattler W (2002) ABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at an in vitro blood-brain barrier constituted of porcine brain capillary endothelial cells. J Biol Chem 277, 42781-42789.
-
(2002)
J Biol Chem
, vol.277
, pp. 42781-42789
-
-
Panzenboeck, U.1
Balazs, Z.2
Sovic, A.3
Hrzenjak, A.4
Levak-Frank, S.5
Wintersperger, A.6
Malle, E.7
Sattler, W.8
-
29
-
-
33646205692
-
Regulatory effects of synthetic liver X receptor-and peroxisomeproliferator activated receptor agonists on sterol transport pathways in polarized cerebrovascular endothelial cells
-
Panzenboeck U, Kratzer I, Sovic A, Wintersperger A, Bernhart E, Hammer A, Malle E, Sattler W (2006) Regulatory effects of synthetic liver X receptor-and peroxisomeproliferator activated receptor agonists on sterol transport pathways in polarized cerebrovascular endothelial cells. Int J Biochem Cell Biol 38, 1314-1329.
-
(2006)
Int J Biochem Cell Biol
, vol.38
, pp. 1314-1329
-
-
Panzenboeck, U.1
Kratzer, I.2
Sovic, A.3
Wintersperger, A.4
Bernhart, E.5
Hammer, A.6
Malle, E.7
Sattler, W.8
-
30
-
-
38349098471
-
Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood-brain barrier
-
Akanuma S, Hori S, Ohtsuki S, Fujiyoshi M, Terasaki T (2008) Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood-brain barrier. Neurochem Int 52, 669-674.
-
(2008)
Neurochem Int
, vol.52
, pp. 669-674
-
-
Akanuma, S.1
Hori, S.2
Ohtsuki, S.3
Fujiyoshi, M.4
Terasaki, T.5
-
31
-
-
78650659385
-
Apicalto-basolateral transport of amyloid-beta peptides through blood-brain barrier cells is mediated by the receptor for advanced glycation end-products and is restricted by Pglycoprotein
-
Candela P, Gosselet F, Saint-Pol J, Sevin E, Boucau MC, Boulanger E, Cecchelli R, Fenart L (2010) Apicalto-basolateral transport of amyloid-beta peptides through blood-brain barrier cells is mediated by the receptor for advanced glycation end-products and is restricted by Pglycoprotein. J Alzheimers Dis 22, 849-859.
-
(2010)
J Alzheimers Dis
, vol.22
, pp. 849-859
-
-
Candela, P.1
Gosselet, F.2
Saint-Pol, J.3
Sevin, E.4
Boucau, M.C.5
Boulanger, E.6
Cecchelli, R.7
Fenart, L.8
-
32
-
-
82155191671
-
Modelling the neurovascular unit and the blood-brain barrier with the unique function of pericytes
-
Vandenhaute E, Dehouck L, Boucau MC, Sevin E, Uzbekov R, TardivelM, Gosselet F, Fenart L, Cecchelli R, DehouckMP (2011) Modelling the neurovascular unit and the blood-brain barrier with the unique function of pericytes. Curr Neurovasc Res 8, 258-269.
-
(2011)
Curr Neurovasc Res
, vol.8
, pp. 258-269
-
-
Vandenhaute, E.1
Dehouck, L.2
Boucau, M.C.3
Sevin, E.4
Uzbekov, R.5
Tardivel, M.6
Gosselet, F.7
Fenart, L.8
Cecchelli, R.9
Dehouck, M.P.10
-
33
-
-
0024441157
-
Bovine brain endothelial cells express tight junctions and monoamine oxidase activity in long-term culture
-
Meresse S, Dehouck MP, Delorme P, Bensaid M, Tauber JP, Delbart C, Fruchart JC, Cecchelli R (1989) Bovine brain endothelial cells express tight junctions and monoamine oxidase activity in long-term culture. J Neurochem 53, 1363-1371.
-
(1989)
J Neurochem
, vol.53
, pp. 1363-1371
-
-
Meresse, S.1
Dehouck, M.P.2
Delorme, P.3
Bensaid, M.4
Tauber, J.P.5
Delbart, C.6
Fruchart, J.C.7
Cecchelli, R.8
-
34
-
-
33646033153
-
HMG-CoA reductase inhibitors induce apoptosis in pericytes
-
Boucher K, Siegel CS, Sharma P, Hauschka PV, Solomon KR (2006) HMG-CoA reductase inhibitors induce apoptosis in pericytes. Microvasc Res 71, 91-102.
-
(2006)
Microvasc Res
, vol.71
, pp. 91-102
-
-
Boucher, K.1
Siegel, C.S.2
Sharma, P.3
Hauschka, P.V.4
Solomon, K.R.5
-
35
-
-
1642277686
-
Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1-but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein
-
Favari E, Lee M, Calabresi L, Franceschini G, Zimetti F, Bernini F, Kovanen PT (2004) Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1-but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein. J Biol Chem 279, 9930-9936.
-
(2004)
J Biol Chem
, vol.279
, pp. 9930-9936
-
-
Favari, E.1
Lee, M.2
Calabresi, L.3
Franceschini, G.4
Zimetti, F.5
Bernini, F.6
Kovanen, P.T.7
-
36
-
-
63649125490
-
Human endothelial cells of the placen tal barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1
-
Stefulj J, Panzenboeck U, Becker T, Hirschmugl B, Schweinzer C, Lang I, Marsche G, Sadjak A, Lang U, Desoye G,Wadsack C (2009) Human endothelial cells of the placen tal barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1. Circ Res 104, 600-608.
-
(2009)
Circ Res
, vol.104
, pp. 600-608
-
-
Stefulj, J.1
Panzenboeck, U.2
Becker, T.3
Hirschmugl, B.4
Schweinzer, C.5
Lang, I.6
Marsche, G.7
Sadjak, A.8
Lang, U.9
Desoye, G.10
Wadsack, C.11
-
37
-
-
8144228674
-
Cellular physiology of cholesterol efflux in vascular endothelial cells
-
O'Connell BJ, Denis M, Genest J (2004) Cellular physiology of cholesterol efflux in vascular endothelial cells. Circulation 110, 2881-2888.
-
(2004)
Circulation
, vol.110
, pp. 2881-2888
-
-
O'connell, B.J.1
Denis, M.2
Genest, J.3
-
38
-
-
40949149021
-
ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-beta peptide (1-40) at the blood-brain barrier
-
Akanuma S, Ohtsuki S, Doi Y, Tachikawa M, Ito S, Hori S, Asashima T, Hashimoto T, Yamada K, Ueda K, Iwatsubo T, Terasaki T (2008) ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-beta peptide (1-40) at the blood-brain barrier. Neurochem Int 52, 956-961.
-
(2008)
Neurochem Int
, vol.52
, pp. 956-961
-
-
Akanuma, S.1
Ohtsuki, S.2
Doi, Y.3
Tachikawa, M.4
Ito, S.5
Hori, S.6
Asashima, T.7
Hashimoto, T.8
Yamada, K.9
Ueda, K.10
Iwatsubo, T.11
Terasaki, T.12
-
39
-
-
78449232720
-
Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice
-
Lefterov I, Fitz NF, Cronican AA, Fogg A, Lefterov P, Kodali R, Wetzel R, Koldamova R (2010) Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice. J Biol Chem 285, 36945-36957.
-
(2010)
J Biol Chem
, vol.285
, pp. 36945-36957
-
-
Lefterov, I.1
Fitz, N.F.2
Cronican, A.A.3
Fogg, A.4
Lefterov, P.5
Kodali, R.6
Wetzel, R.7
Koldamova, R.8
-
40
-
-
38349026548
-
Lipoprotein receptor-related protein-1 mediates amyloidbeta-mediated cell death of cerebrovascular cells
-
WilhelmusMM,Otte-Holler I, van Triel JJ,Veerhuis R, Maat-Schieman ML, Bu G, de Waal RM, Verbeek MM (2007) Lipoprotein receptor-related protein-1 mediates amyloidbeta-mediated cell death of cerebrovascular cells. Am J Pathol 171, 1989-1999.
-
(2007)
Am J Pathol
, vol.171
, pp. 1989-1999
-
-
Wilhelmus, M.M.1
Otte-Holler, I.2
Van Triel, J.J.3
Veerhuis, R.4
Maat-Schieman, M.L.5
Bu, G.6
De Waal, R.M.7
Verbeek, M.M.8
-
41
-
-
0031017399
-
Rapid degeneration of cultured human brain pericytes by amyloid beta protein
-
Verbeek MM, de Waal RM, Schipper JJ, Van Nostrand WE (1997) Rapid degeneration of cultured human brain pericytes by amyloid beta protein. J Neurochem 68, 1135-1141.
-
(1997)
J Neurochem
, vol.68
, pp. 1135-1141
-
-
Verbeek, M.M.1
De Waal, R.M.2
Schipper, J.J.3
Van Nostrand, W.E.4
-
42
-
-
3242682550
-
Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistanceassociated proteins in a in vitro model of the blood-brain barrier
-
Berezowski V, Landry C, Dehouck MP, Cecchelli R, Fenart L (2004) Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistanceassociated proteins in an in vitro model of the blood-brain barrier. Brain Res 1018, 1-9.
-
(2004)
Brain Res
, vol.1018
, pp. 1-9
-
-
Berezowski, V.1
Landry, C.2
Dehouck, M.P.3
Cecchelli, R.4
Fenart, L.5
-
43
-
-
33751096969
-
Crossing the barrier: Oxysterols as cholesterol transporters and metabolic modulators in the brain
-
Bjorkhem I (2006) Crossing the barrier: Oxysterols as cholesterol transporters and metabolic modulators in the brain. J Intern Med 260, 493-508.
-
(2006)
J Intern Med
, vol.260
, pp. 493-508
-
-
Bjorkhem, I.1
-
44
-
-
3042615507
-
Cross-inhibition of SRBI-and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide
-
Nieland TJ, Chroni A, Fitzgerald ML, Maliga Z, Zannis VI, Kirchhausen T, Krieger M (2004) Cross-inhibition of SRBI-and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide. J Lipid Res 45, 1256-1265.
-
(2004)
J Lipid Res
, vol.45
, pp. 1256-1265
-
-
Nieland, T.J.1
Chroni, A.2
Fitzgerald, M.L.3
Maliga, Z.4
Zannis, V.I.5
Kirchhausen, T.6
Krieger, M.7
-
45
-
-
3142709408
-
Probucol inactivatesABCA1in the plasma membrane with respect to its mediation of apolipoprotein binding and high density lipoprotein assembly and to its proteolytic degradation
-
Wu CA, Tsujita M, Hayashi M, Yokoyama S (2004) Probucol inactivatesABCA1in the plasma membrane with respect to its mediation of apolipoprotein binding and high density lipoprotein assembly and to its proteolytic degradation. J Biol Chem 279, 30168-30174.
-
(2004)
J Biol Chem
, vol.279
, pp. 30168-30174
-
-
Wu, C.A.1
Tsujita, M.2
Hayashi, M.3
Yokoyama, S.4
-
46
-
-
38849122775
-
Liver X receptors (LXRs). Part I: Structure, function, regulation of activity, and role in lipid metabolism
-
Wojcicka G, Jamroz-Wisniewska A, Horoszewicz K, Beltowski J (2007) Liver X receptors (LXRs). Part I: Structure, function, regulation of activity, and role in lipid metabolism. Postepy Hig Med Dosw (Online) 61, 736-759.
-
(2007)
Postepy Hig Med Dosw (Online)
, vol.61
, pp. 736-759
-
-
Wojcicka, G.1
Jamroz-Wisniewska, A.2
Horoszewicz, K.3
Beltowski, J.4
-
47
-
-
38549141572
-
Cellular cholesterol trafficking and compartmentalization
-
Ikonen E (2008) Cellular cholesterol trafficking and compartmentalization. Nat Rev Mol Cell Biol 9, 125-138.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 125-138
-
-
Ikonen, E.1
-
48
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD (1993) Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A 90, 1977-1981.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
49
-
-
0033968648
-
Apolipoprotein e exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture
-
Michikawa M, Fan QW, Isobe I, Yanagisawa K (2000) Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture. J Neurochem 74, 1008-1016.
-
(2000)
J Neurochem
, vol.74
, pp. 1008-1016
-
-
Michikawa, M.1
Fan, Q.W.2
Isobe, I.3
Yanagisawa, K.4
-
50
-
-
2142703732
-
Molecular interactions between apoE and ABCA1: Impact on apoE lipidation
-
Krimbou L, Denis M, Haidar B, Carrier M, Marcil M, Genest J Jr (2004) Molecular interactions between apoE and ABCA1: Impact on apoE lipidation. J Lipid Res 45, 839-848.
-
(2004)
J Lipid Res
, vol.45
, pp. 839-848
-
-
Krimbou, L.1
Denis, M.2
Haidar, B.3
Carrier, M.4
Marcil, M.5
Genest Jr., J.6
-
51
-
-
79959772357
-
Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance
-
Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM (2011) Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance. Sci Transl Med 3, 57-67.
-
(2011)
Sci Transl Med
, vol.3
, pp. 57-67
-
-
Castellano, J.M.1
Kim, J.2
Stewart, F.R.3
Jiang, H.4
Demattos, R.B.5
Patterson, B.W.6
Fagan, A.M.7
Morris, J.C.8
Mawuenyega, K.G.9
Cruchaga, C.10
Goate, A.M.11
Bales, K.R.12
Paul, S.M.13
Bateman, R.J.14
Holtzman, D.M.15
-
52
-
-
57449084208
-
ApoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain
-
Deane R, Sagare A, Hamm K, Parisi M, Lane S, Finn MB, Holtzman DM, Zlokovic BV (2008) apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain. J Clin Invest 118, 4002-4013.
-
(2008)
J Clin Invest
, vol.118
, pp. 4002-4013
-
-
Deane, R.1
Sagare, A.2
Hamm, K.3
Parisi, M.4
Lane, S.5
Finn, M.B.6
Holtzman, D.M.7
Zlokovic, B.V.8
-
53
-
-
79958773215
-
Liver X receptor activation restores memory in aged AD mice without reducing amyloid
-
Vanmierlo T, Rutten K, Dederen J, Bloks VW, van Vark-van der Zee LC, Kuipers F, Kiliaan A, Blokland A, Sijbrands EJ, Steinbusch H, Prickaerts J, Lutjohann D, Mulder M (2011) Liver X receptor activation restores memory in aged AD mice without reducing amyloid. Neurobiol Aging 32, 1262-1272.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 1262-1272
-
-
Vanmierlo, T.1
Rutten, K.2
Dederen, J.3
Bloks, V.W.4
Van Vark-Van Der Zee, L.C.5
Kuipers, F.6
Kiliaan, A.7
Blokland, A.8
Sijbrands, E.J.9
Steinbusch, H.10
Prickaerts, J.11
Lutjohann, D.12
Mulder, M.13
-
54
-
-
74149083432
-
Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease
-
Hudry E,Van Dam D,KulikW, De Deyn PP, Stet FS, Ahouansou O, Benraiss A, Delacourte A, Bougneres P, Aubourg P, Cartier N (2010) Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease. Mol Ther 18, 44-53.
-
(2010)
Mol Ther
, vol.18
, pp. 44-53
-
-
Hudry, E.1
Van Dam, D.2
Kulik, W.3
De Deyn, P.P.4
Stet, F.S.5
Ahouansou, O.6
Benraiss, A.7
Delacourte, A.8
Bougneres, P.9
Aubourg, P.10
Cartier, N.11
-
55
-
-
38849086036
-
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease
-
Wahrle SE, Jiang H, Parsadanian M, Kim J, Li A, Knoten A, Jain S, Hirsch-Reinshagen V, Wellington CL, Bales KR, Paul SM, Holtzman DM (2008) Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. J Clin Invest 118, 671-682.
-
(2008)
J Clin Invest
, vol.118
, pp. 671-682
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
Kim, J.4
Li, A.5
Knoten, A.6
Jain, S.7
Hirsch-Reinshagen, V.8
Wellington, C.L.9
Bales, K.R.10
Paul, S.M.11
Holtzman, D.M.12
-
56
-
-
30044442937
-
Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease
-
Wahrle SE, Jiang H, Parsadanian M, Hartman RE, Bales KR, Paul SM, Holtzman DM (2005) Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease. J Biol Chem 280, 43236-43242.
-
(2005)
J Biol Chem
, vol.280
, pp. 43236-43242
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
Hartman, R.E.4
Bales, K.R.5
Paul, S.M.6
Holtzman, D.M.7
-
57
-
-
30044438463
-
Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice
-
Koldamova R, Staufenbiel M, Lefterov I (2005) Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice. J Biol Chem 280, 43224-43235.
-
(2005)
J Biol Chem
, vol.280
, pp. 43224-43235
-
-
Koldamova, R.1
Staufenbiel, M.2
Lefterov, I.3
-
58
-
-
30044441879
-
The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease
-
Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL (2005) The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease. J Biol Chem 280, 43243-43256.
-
(2005)
J Biol Chem
, vol.280
, pp. 43243-43256
-
-
Hirsch-Reinshagen, V.1
Maia, L.F.2
Burgess, B.L.3
Blain, J.F.4
Naus, K.E.5
McIsaac, S.A.6
Parkinson, P.F.7
Chan, J.Y.8
Tansley, G.H.9
Hayden, M.R.10
Poirier, J.11
Van Nostrand, W.12
Wellington, C.L.13
-
59
-
-
77953258151
-
The role of ATPbinding cassette transporter A1 in Alzheimer's disease and neurodegeneration
-
Koldamova R, Fitz NF, Lefterov I (2010) The role of ATPbinding cassette transporter A1 in Alzheimer's disease and neurodegeneration. Biochim Biophys Acta 1801, 824-830.
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 824-830
-
-
Koldamova, R.1
Fitz, N.F.2
Lefterov, I.3
-
60
-
-
33748949567
-
In situ localization of P-glycoprotein (ABC 1) in human and rat brain
-
Bendayan R, Ronaldson PT, Gingras D, Bendayan M (2006) In situ localization of P-glycoprotein (ABCB1) in human and rat brain. J Histochem Cytochem 54, 1159-1167.
-
(2006)
J Histochem Cytochem
, vol.54
, pp. 1159-1167
-
-
Bendayan, R.1
Ronaldson, P.T.2
Gingras, D.3
Bendayan, M.4
-
61
-
-
70450219539
-
Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease
-
Martins IJ, Berger T, Sharman MJ, Verdile G, Fuller SJ, Martins RN (2009) Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease. J Neurochem 111, 1275-1308.
-
(2009)
J Neurochem
, vol.111
, pp. 1275-1308
-
-
Martins, I.J.1
Berger, T.2
Sharman, M.J.3
Verdile, G.4
Fuller, S.J.5
Martins, R.N.6
-
62
-
-
80052965098
-
Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target gene In Vivo
-
Shafaati M, Olin M, Bavner A, Pettersson H, Rozell B, Meaney S, Parini P, Bjorkhem I (2011) Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo. J Intern Med 270, 377-387.
-
(2011)
J Intern Med
, vol.270
, pp. 377-387
-
-
Shafaati, M.1
Olin, M.2
Bavner, A.3
Pettersson, H.4
Rozell, B.5
Meaney, S.6
Parini, P.7
Bjorkhem, I.8
|