-
1
-
-
0034458454
-
The cerebral proteopathies: Neurodegenerative disorders of protein conformation and assembly
-
Walker LC, LeVine HL. The cerebral proteopathies: neurodegenerative disorders of protein conformation and assembly. Mol Neurobiol 2000; 21:83-95.
-
(2000)
Mol Neurobiol
, vol.21
, pp. 83-95
-
-
Walker, L.C.1
LeVine, H.L.2
-
2
-
-
0033600274
-
Translating cell biology into therapeutic advances in Alzheimer's disease
-
Selkoe DJ. Translating cell biology into therapeutic advances in Alzheimer's disease. Nature 1999; 399:A23-A31.
-
(1999)
Nature
, vol.399
-
-
Selkoe, D.J.1
-
3
-
-
0034521392
-
Clearance of Alzheimer's amyloid-β 1-40 peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
-
Shibata M, Yamada S, Kumar SR, Calero M, Bading J, Frangione B, et al. Clearance of Alzheimer's amyloid-β 1-40 peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J Clin Invest 2000; 106:1489-1499.
-
(2000)
J Clin Invest
, vol.106
, pp. 1489-1499
-
-
Shibata, M.1
Yamada, S.2
Kumar, S.R.3
Calero, M.4
Bading, J.5
Frangione, B.6
-
4
-
-
0035112889
-
β-amyloid efflux mediated by p-glycoprotein
-
Lam FC, Liu R, Shapiro AB, Renoir JM, Sharom FJ, Reiner PB. β-amyloid efflux mediated by p-glycoprotein. J Neurochem 2001; 76:1121-1128.
-
(2001)
J Neurochem
, vol.76
, pp. 1121-1128
-
-
Lam, F.C.1
Liu, R.2
Shapiro, A.B.3
Renoir, J.M.4
Sharom, F.J.5
Reiner, P.B.6
-
5
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
Juliano RL, Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 1976; 455:152-162.
-
(1976)
Biochim Biophys Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
6
-
-
0033724658
-
The effect of rifampin treatment on intestinal expression of human MRP transporters
-
Fromm MF, Kaufmann HM, Fritz P, Burk O, Kroemer HK, Warzok RW, et al. The effect of rifampin treatment on intestinal expression of human MRP transporters. Am J Pathol 2000; 157:1575-1580.
-
(2000)
Am J Pathol
, vol.157
, pp. 1575-1580
-
-
Fromm, M.F.1
Kaufmann, H.M.2
Fritz, P.3
Burk, O.4
Kroemer, H.K.5
Warzok, R.W.6
-
7
-
-
0033980182
-
P-glycoprotein: A defense mechanism limiting oral bioavailability and CNS accumulation of drugs
-
Fromm MF. P-glycoprotein: a defense mechanism limiting oral bioavailability and CNS accumulation of drugs. Int J Clin Pharmacol Ther 2000; 38:69-74.
-
(2000)
Int J Clin Pharmacol Ther
, vol.38
, pp. 69-74
-
-
Fromm, M.F.1
-
8
-
-
0031158805
-
The physiological function of drug transporting P-glycoproteins
-
Schinkel AH. The physiological function of drug transporting P-glycoproteins. Semin Cancer Biol 1997; 8:161-170.
-
(1997)
Semin Cancer Biol
, vol.8
, pp. 161-170
-
-
Schinkel, A.H.1
-
9
-
-
0035054725
-
The gut as a barrier to drug absorption. Combined role of cytochrome P4503A and P-glycoprotein
-
Zhang Y, Benet LZ. The gut as a barrier to drug absorption. Combined role of cytochrome P4503A and P-glycoprotein. Clin Pharmacokinet 2001; 40:159-168.
-
(2001)
Clin Pharmacokinet
, vol.40
, pp. 159-168
-
-
Zhang, Y.1
Benet, L.Z.2
-
10
-
-
0032754284
-
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
-
Greiner B, Eichelbaum M, Fritz P, Kreichgauer HP, von Richter O, Zundler J, Kroemer HK. The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. J Clin Invest 1999; 104:147-153.
-
(1999)
J Clin Invest
, vol.104
, pp. 147-153
-
-
Greiner, B.1
Eichelbaum, M.2
Fritz, P.3
Kreichgauer, H.P.4
Von Richter, O.5
Zundler, J.6
Kroemer, H.K.7
-
11
-
-
0033865280
-
Oral bioavailability of digoxin is enhanced by talinolol: Evidence for involvement of intestinal P-glycoprotein
-
Westphal K, Weinbrenner A, Gießmann T, Stuhr M, Franke G, Zschiesche M, et al. Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P-glycoprotein. Clin Pharmacol Ther 2000; 68:6-12.
-
(2000)
Clin Pharmacol Ther
, vol.68
, pp. 6-12
-
-
Westphal, K.1
Weinbrenner, A.2
Gießmann, T.3
Stuhr, M.4
Franke, G.5
Zschiesche, M.6
-
12
-
-
0033753435
-
Induction of p-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: A new type of drug/drug interaction
-
Westphal K, Weinbrenner A, Zschiesche M, Franke G, Knoke M, Oertel R, et al. Induction of p-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction. Clin Pharmacol Ther 2000; 68:345-355.
-
(2000)
Clin Pharmacol Ther
, vol.68
, pp. 345-355
-
-
Westphal, K.1
Weinbrenner, A.2
Zschiesche, M.3
Franke, G.4
Knoke, M.5
Oertel, R.6
-
13
-
-
0000006828
-
Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)
-
Johne A, Brockmoeller J, Bauer S, Maurer A, Langheinrich M, Roots I. Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum). Clin Pharmacol Ther 1999; 66:338-345.
-
(1999)
Clin Pharmacol Ther
, vol.66
, pp. 338-345
-
-
Johne, A.1
Brockmoeller, J.2
Bauer, S.3
Maurer, A.4
Langheinrich, M.5
Roots, I.6
-
14
-
-
0033514320
-
Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine
-
Fromm MF, Kim RB, Stein CM, Wilkinson GR, Roden DM. Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine. Circulation 1999; 99:552-557.
-
(1999)
Circulation
, vol.99
, pp. 552-557
-
-
Fromm, M.F.1
Kim, R.B.2
Stein, C.M.3
Wilkinson, G.R.4
Roden, D.M.5
-
15
-
-
0032823160
-
Intestinal secretion of intravenous talinolol is inhibited by luminal R-verapamil
-
Gramatté T, Oertel R. Intestinal secretion of intravenous talinolol is inhibited by luminal R-verapamil. Clin Pharmacol Ther 1999; 66:239-245.
-
(1999)
Clin Pharmacol Ther
, vol.66
, pp. 239-245
-
-
Gramatté, T.1
Oertel, R.2
-
16
-
-
0035104031
-
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
-
Cascorbi I, Gerloff T, Johne A, Meisel C, Hoffmeyer S, Schwab M, et al. Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther 2001; 69:169-174.
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 169-174
-
-
Cascorbi, I.1
Gerloff, T.2
Johne, A.3
Meisel, C.4
Hoffmeyer, S.5
Schwab, M.6
-
17
-
-
0034724324
-
Functional polymorphisms of the human multidrug resistance gene: Multiple sequence variations and correlation with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmöller Johne A, Cascorbi I, et al. Functional polymorphisms of the human multidrug resistance gene: multiple sequence variations and correlation with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 2000; 97:3473-3478.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brockmöller Johne, A.5
Cascorbi, I.6
-
18
-
-
0034811880
-
Isolation of endothelial cells from brain, lung, and kidney: Expression of the multidrug resistance P- glycoprotein isoforms
-
Demeule M, Labelle M, Regina A, Berthelet F, Beliveau R. Isolation of endothelial cells from brain, lung, and kidney: expression of the multidrug resistance P- glycoprotein isoforms. Biochem Biophys Res Commun 2001; 281:827-834.
-
(2001)
Biochem Biophys Res Commun
, vol.281
, pp. 827-834
-
-
Demeule, M.1
Labelle, M.2
Regina, A.3
Berthelet, F.4
Beliveau, R.5
-
19
-
-
0033961896
-
Brain microvascular P-glycoprotein and a revised model of multidrug resistance in brain
-
Golden PL, Pardridge WM. Brain microvascular P-glycoprotein and a revised model of multidrug resistance in brain. Cell Mol Neurobiol 2000; 20:165-181.
-
(2000)
Cell Mol Neurobiol
, vol.20
, pp. 165-181
-
-
Golden, P.L.1
Pardridge, W.M.2
-
20
-
-
0033664346
-
Xenobiotic transport across isolated brain microvessels studied by confocal microscopy
-
Miller DS, Mobmann SN, Gutmann H, Toeroek M, Drewe J, Fricker G. Xenobiotic transport across isolated brain microvessels studied by confocal microscopy. Mol Pharmacol 2000; 58:1357-1367.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 1357-1367
-
-
Miller, D.S.1
Mobmann, S.N.2
Gutmann, H.3
Toeroek, M.4
Drewe, J.5
Fricker, G.6
-
21
-
-
18244416706
-
Apolipoprotein E4 promotes the early deposition of Aβ42 and then Aβ40 in the elderly
-
Walker LC, Pahnke J, Madauβ M, Vogelgesang S, Pahnke A, Herbst EW, et al. Apolipoprotein E4 promotes the early deposition of Aβ42 and then Aβ40 in the elderly. Acta Neuropathol 2000; 100:36-42.
-
(2000)
Acta Neuropathol
, vol.100
, pp. 36-42
-
-
Walker, L.C.1
Pahnke, J.2
Madauß, M.3
Vogelgesang, S.4
Pahnke, A.5
Herbst, E.W.6
-
22
-
-
0032457459
-
Apolipoprotein E promotes incipient Alzheimer pathology in the elderly
-
Warzok R, Kessler C, Apel G, Schwarz A, Egensperger R, Schreiber D, et al. Apolipoprotein E promotes incipient Alzheimer pathology in the elderly. Alzheimer Dis Relat Dis 1998; 12:33-39.
-
(1998)
Alzheimer Dis Relat Dis
, vol.12
, pp. 33-39
-
-
Warzok, R.1
Kessler, C.2
Apel, G.3
Schwarz, A.4
Egensperger, R.5
Schreiber, D.6
-
23
-
-
0034516988
-
Towards a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid β-protein
-
Selkoe DJ. Towards a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid β-protein. Ann NY Acad Sci 2000; 924:17-25.
-
(2000)
Ann NY Acad Sci
, vol.924
, pp. 17-25
-
-
Selkoe, D.J.1
-
24
-
-
0032323641
-
Evolutionary relationships among ABC transporters
-
Croop JM. Evolutionary relationships among ABC transporters. Methods Enzymol 1998; 292:101-117.
-
(1998)
Methods Enzymol
, vol.292
, pp. 101-117
-
-
Croop, J.M.1
-
25
-
-
0342378042
-
Interaction of Alzheimer β-amyloid peptide (1-40) with lipid membranes
-
Terzi E, Holzemann G, Seelig J. Interaction of Alzheimer β-amyloid peptide (1-40) with lipid membranes. J Biochem 1997; 36:14845-14852.
-
(1997)
J Biochem
, vol.36
, pp. 14845-14852
-
-
Terzi, E.1
Holzemann, G.2
Seelig, J.3
-
26
-
-
0035882515
-
Pharmacogenetics of the human drug-transporter gene MDR1: Impact of polymorphisms on pharmacotherapy
-
Brinkmann U, Roots I, Eichelbaum M. Pharmacogenetics of the human drug-transporter gene MDR1: impact of polymorphisms on pharmacotherapy. Drug Discov Today 2001; 6:835-839.
-
(2001)
Drug Discov Today
, vol.6
, pp. 835-839
-
-
Brinkmann, U.1
Roots, I.2
Eichelbaum, M.3
-
27
-
-
0034997034
-
Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene
-
Tanabe M, Ieiri I, Nagata N, Inoue K, Ito S, Kanamori Y, et al. Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene J Pharmacol Exp Ther 2001; 297:1137-1143.
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 1137-1143
-
-
Tanabe, M.1
Ieiri, I.2
Nagata, N.3
Inoue, K.4
Ito, S.5
Kanamori, Y.6
-
28
-
-
0031655793
-
The role of ApoE polymorphism in late-onset dementias
-
Corder EH, Lannfelt L, Bogdanovic N, Fratiglioni L, Mori H. The role of ApoE polymorphism in late-onset dementias. Cell Mol Life Sci 1998; 54:928-934.
-
(1998)
Cell Mol Life Sci
, vol.54
, pp. 928-934
-
-
Corder, E.H.1
Lannfelt, L.2
Bogdanovic, N.3
Fratiglioni, L.4
Mori, H.5
-
30
-
-
0034051677
-
Enhanced cerebral uptake of receptor ligands by modulation of p-glycoprotein function in the blood-brain barrier
-
Doze P, van Waarde A, Elsinga PH, Hendrikse NH, Vaalburg W. Enhanced cerebral uptake of receptor ligands by modulation of p-glycoprotein function in the blood-brain barrier. Synapse 2000; 36:66-74.
-
(2000)
Synapse
, vol.36
, pp. 66-74
-
-
Doze, P.1
Van Waarde, A.2
Elsinga, P.H.3
Hendrikse, N.H.4
Vaalburg, W.5
-
31
-
-
0001504829
-
Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo
-
Fassbender K, Simons M, Bergmann C, Stroick M, Lütjohann D, Keller P, et al. Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo. Proc Natl Acad Sci USA 2001; 98:5856-5861.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5856-5861
-
-
Fassbender, K.1
Simons, M.2
Bergmann, C.3
Stroick, M.4
Lütjohann, D.5
Keller, P.6
-
32
-
-
0035076611
-
HMG-CoA reductase inhibitors and P-glycoprotein modulation
-
Bogman K, Peyer A-K, Török M, Küsters E, Drewe J. HMG-CoA reductase inhibitors and P-glycoprotein modulation. Br J Pharmacol 2001; 132:1183-1192.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 1183-1192
-
-
Bogman, K.1
Peyer, A.-K.2
Török, M.3
Küsters, E.4
Drewe, J.5
-
33
-
-
0032819120
-
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats
-
Hooiveld GJEJ, Vos TA, Scheffer GL, van Goor H, Koning H, Bloks V, et al. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats. Gastroenterology 1999; 117:678-687.
-
(1999)
Gastroenterology
, vol.117
, pp. 678-687
-
-
Hooiveld, G.J.E.J.1
Vos, T.A.2
Scheffer, G.L.3
Van Goor, H.4
Koning, H.5
Bloks, V.6
|