Involvement of multidrug resistance associated protein 1 (Mrp1) in the efflux transport of 17β estradiol-D-17β-glucuronide (E 217βG) across the blood-brain barrier

Pharmaceutical Research

Volumn 20, Issue 9, 2003, Pages 1394-1400

  Sugiyama, Daisuke ^a   Kusuhara, Hiroyuki ^a   Lee, Yong Joo ^a   Sugiyama, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Blood brain barrier; Efflux transport; Mrp; Organic anion

Indexed keywords

ESTRADIOL 17 GLUCURONIDE; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2;

ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BLOOD BRAIN BARRIER; BRAIN HOMOGENATE; BRAIN LEVEL; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG TRANSPORT; DRUG UPTAKE; KNOCKOUT MOUSE; MALE; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; WILD TYPE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN; CAPILLARIES; CARRIER PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESTRADIOL; MALE; MICE; MICE, KNOCKOUT; MICROINJECTIONS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECIES SPECIFICITY; TIME FACTORS;

EID: 0141790752     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025749925541     Document Type: Article

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