메뉴 건너뛰기




Volumn 105, Issue 3, 2000, Pages 279-285

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

Author keywords

[No Author keywords available]

Indexed keywords

ETOPOFOS; ETOPOSIDE; MULTIDRUG RESISTANCE PROTEIN;

EID: 0033975098     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI8267     Document Type: Article
Times cited : (357)

References (52)
  • 2
    • 13044249156 scopus 로고    scopus 로고
    • A multidrug resistance transporter from human MCF-7 breast cancer cells
    • Doyle, R.A., et al. 1998. A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc. Natl. Acad Sci. USA. 95:15665-15670.
    • (1998) Proc. Natl. Acad Sci. USA. , vol.95 , pp. 15665-15670
    • Doyle, R.A.1
  • 3
    • 0032404092 scopus 로고    scopus 로고
    • A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
    • Allikmets, R., Schriml, L.M., Hutchinson, A., Romano-Sp:ca, V., and Dean. M. 1998. A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res. 58:5337-5339.
    • (1998) Cancer Res. , vol.58 , pp. 5337-5339
    • Allikmets, R.1    Schriml, L.M.2    Hutchinson, A.3    Romano-Spca, V.4    Dean, M.5
  • 4
    • 0032895533 scopus 로고    scopus 로고
    • Molecular cloning of cdnas which are highly overexpressed in mitoxantrone-resistant cells: Demonstration of homology to ABC transport genes
    • Miyake, K., et al. 1999. Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes. Canser Res. 59:8-13.
    • (1999) Canser Res. , vol.59 , pp. 8-13
    • Miyake, K.1
  • 5
    • 17144465167 scopus 로고    scopus 로고
    • ATP-dependent transport of glutathione S-conjugates by the multidrug resistance protein MRP1 and its apical isoform MRP2
    • Keppler, D., Leier, I., Jedlitschky, G , and König, J. 1998. ATP-dependent transport of glutathione S-conjugates by the multidrug resistance protein MRP1 and its apical isoform MRP2. Chem. Biol. Interact. 111-112:153-161.
    • (1998) Chem. Biol. Interact. , vol.111-112 , pp. 153-161
    • Keppler, D.1    Leier, I.2    Jedlitschky, G.3    König, J.4
  • 6
    • 0032211417 scopus 로고    scopus 로고
    • Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP
    • Cole, S.P., and Deeley, R.G. 1998. Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP. Bioessays 20:931-940.
    • (1998) Bioessays , vol.20 , pp. 931-940
    • Cole, S.P.1    Deeley, R.G.2
  • 7
    • 0027095653 scopus 로고
    • Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
    • Cole, S.P.C., et al 1992. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science. 258:1650-1654.
    • (1992) Science , vol.258 , pp. 1650-1654
    • Cole, S.P.C.1
  • 8
    • 0028567035 scopus 로고
    • The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump
    • Zaman, G.J.R., et al. 1994. The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump. Proc. Natl. Acad. Sci. USA. 91:8822-8826.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8822-8826
    • Zaman, G.J.R.1
  • 9
    • 0027960078 scopus 로고
    • Pharmalogical characterization of multidrug resistant MRP-transfected human tumor cells
    • Cole, S.P.C., et al. 1994. Pharmalogical characterization of multidrug resistant MRP-transfected human tumor cells. Cancer Res. 54:5902-5910.
    • (1994) Cancer Res. , vol.54 , pp. 5902-5910
    • Cole, S.P.C.1
  • 10
    • 0030747386 scopus 로고    scopus 로고
    • The GS-X pump in plant, yeast, and animal cells: Structure, function, and gene expression
    • Ishikawa, T., Li, Z.S., Lu, Y.P., and Rea, P.A. 1997. The GS-X pump in plant, yeast, and animal cells: structure, function, and gene expression. Biosci. Rep. 17:189-207.
    • (1997) Biosci. Rep. , vol.17 , pp. 189-207
    • Ishikawa, T.1    Li, Z.S.2    Lu, Y.P.3    Rea, P.A.4
  • 11
    • 0027984511 scopus 로고
    • 4 and structurally related conjugates
    • 4 and structurally related conjugates. J. Biol. Chem. 269:27807-27810.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27807-27810
    • Leier, I.1
  • 12
    • 0030063480 scopus 로고
    • Transport of glutathione, glucuronate, and sulface conjugates by the MRP gene-encoded conjugate export pump
    • Jedlitschky, G., et al. 1946. Transport of glutathione, glucuronate, and sulface conjugates by the MRP gene-encoded conjugate export pump. Cancer Res. 56:988-994.
    • (1946) Cancer Res. , vol.56 , pp. 988-994
    • Jedlitschky, G.1
  • 13
    • 0028578004 scopus 로고
    • Overexpression of the gene encoding the multidrug resistance associated protein results in increased ATP-dependent glutathione S-conjugate transport
    • Müllet, M., et al. 1994. Overexpression of the gene encoding the multidrug resistance associated protein results in increased ATP-dependent glutathione S-conjugate transport. Proc. Natl. Acad Sci. USA. 91:13033-13037.
    • (1994) Proc. Natl. Acad Sci. USA , vol.91 , pp. 13033-13037
    • Müllet, M.1
  • 14
    • 20244386956 scopus 로고    scopus 로고
    • Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
    • Wijnholds, J., et al. 1997. Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein. Nat. Med. 3:1275-1279.
    • (1997) Nat. Med. , vol.3 , pp. 1275-1279
    • Wijnholds, J.1
  • 15
    • 0029095763 scopus 로고
    • Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein
    • Zaman, G.J.R., et al. 1995. Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein. Proc. Natl. Acad. Sci. USA. 92:7690-7694.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7690-7694
    • Zaman, G.J.R.1
  • 16
    • 0032534064 scopus 로고    scopus 로고
    • Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): Evidence for cotransport with reduced glutathione
    • Loe, D.W., Deeley, R.G., and Cole, S.P. 1998. Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione. Cancer Res. 58:5130-5136.
    • (1998) Cancer Res. , vol.58 , pp. 5130-5136
    • Loe, D.W.1    Deeley, R.G.2    Cole, S.P.3
  • 17
    • 0033021424 scopus 로고    scopus 로고
    • ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1
    • Renes, J., de Vries, E.G., Nienhius, E.F., Jansen, P.L., and Müller, M. 1999. ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1. Br. J. Pharmacol 126:681-688.
    • (1999) Br. J. Pharmacol , vol.126 , pp. 681-688
    • Renes, J.1    De Vries, E.G.2    Nienhius, E.F.3    Jansen, P.L.4    Müller, M.5
  • 18
    • 0030678131 scopus 로고    scopus 로고
    • Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins
    • Rappa, G., Lorico, A., Flavell, R.A., and Sartorelli, A.C. 1997. Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins. Cancer Res. 57:5232-5237.
    • (1997) Cancer Res. , vol.57 , pp. 5232-5237
    • Rappa, G.1    Lorico, A.2    Flavell, R.A.3    Sartorelli, A.C.4
  • 19
    • 4243801613 scopus 로고    scopus 로고
    • Normal viability and altered pharmacokinetics in mice lacking Mdr1-type (drug-transporting) P-glycoproteins
    • Schinkel, A.H., et al. 1997. Normal viability and altered pharmacokinetics in mice lacking Mdr1-type (drug-transporting) P-glycoproteins. Proc. Natl. Acad. Sci. USA. 94:4028-4033.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4028-4033
    • Schinkel, A.H.1
  • 20
    • 0028229150 scopus 로고
    • Disruption of the mouse Mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
    • Schinkel, A.H., et al. 1994. Disruption of the mouse Mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell. 77:491-502.
    • (1994) Cell , vol.77 , pp. 491-502
    • Schinkel, A.H.1
  • 21
    • 0030665969 scopus 로고    scopus 로고
    • Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione
    • Lorico, A., et al. 1997. Disruption of the murine MRP (Multidrug Resistance Protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione. Cancer Res. 57:5238-5242.
    • (1997) Cancer Res. , vol.57 , pp. 5238-5242
    • Lorico, A.1
  • 22
    • 12644278301 scopus 로고    scopus 로고
    • Limited oral bioavailability and active epithelial excretion of paclitaxel (taxol) caused by P-glycoprotein in the intestine
    • Sparreboom, A., et al. 1997. Limited oral bioavailability and active epithelial excretion of paclitaxel (taxol) caused by P-glycoprotein in the intestine. Proc. Natl. Acad. Sci. USA. 94:2011-2035.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2011-2035
    • Sparreboom, A.1
  • 23
    • 0031757312 scopus 로고    scopus 로고
    • BBB transport and P-glycoprotein functionality using MDRIA ( / ) and wild-type mice. Total brain versus microdialysis concentration profiles of rhodamine-123
    • de Lange, E.C., de Bock, G., Schinkel, A.H., de Boer, A.G., and Breimer, D.D. 1998. BBB transport and P-glycoprotein functionality using MDRIA ( / ) and wild-type mice. Total brain versus microdialysis concentration profiles of rhodamine-123. Pharm. Res. 15:1657-1665.
    • (1998) Pharm. Res. , vol.15 , pp. 1657-1665
    • De Lange, E.C.1    De Bock, G.2    Schinkel, A.H.3    De Boer, A.G.4    Breimer, D.D.5
  • 24
    • 0030781139 scopus 로고    scopus 로고
    • Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833
    • Mayer, U., et al. 1997. Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833. J. Clin. Invest. 100:2430-2436.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2430-2436
    • Mayer, U.1
  • 25
    • 0000712439 scopus 로고
    • Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
    • Cordon-Cardo, C., et al. 1989. Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc. Natl. Acad. Sci. USA. 86:695-698.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 695-698
    • Cordon-Cardo, C.1
  • 26
    • 0032494133 scopus 로고    scopus 로고
    • Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules againts drug-induced damage
    • Wijnholds, J., et al. 1998. Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules againts drug-induced damage. J. Exp. Med. 188:797-808.
    • (1998) J. Exp. Med. , vol.188 , pp. 797-808
    • Wijnholds, J.1
  • 27
    • 9244261944 scopus 로고    scopus 로고
    • Distribution of the multidrug resistance-associated protein (MRP) in normal and malignant human tissues
    • Flens, M.J., et al. 1996. Distribution of the multidrug resistance-associated protein (MRP) in normal and malignant human tissues. Am. J. Pathol. 148:1237-1247.
    • (1996) Am. J. Pathol. , vol.148 , pp. 1237-1247
    • Flens, M.J.1
  • 28
    • 0028171453 scopus 로고
    • Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies
    • Hipfner, D.R., Gauldie, S.D., Deeley, R.G., and Cole, S.P. 1994. Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies. Cancer Res. 54:5788-5792.
    • (1994) Cancer Res. , vol.54 , pp. 5788-5792
    • Hipfner, D.R.1    Gauldie, S.D.2    Deeley, R.G.3    Cole, S.P.4
  • 29
    • 0031694229 scopus 로고    scopus 로고
    • Immunohistochemical detection of multidrug resistance protein in human lung cancer and normal lung
    • Wright, S.R., et al. 1998. Immunohistochemical detection of multidrug resistance protein in human lung cancer and normal lung. Clin. Cancer Res. 4:2279-2289.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 2279-2289
    • Wright, S.R.1
  • 30
    • 0029133131 scopus 로고
    • Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from canalicular membrane in transport-deficient mutant hepatocytes
    • Mayer, R., et al. 1995. Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from canalicular membrane in transport-deficient mutant hepatocytes. J. Cell Biol. 131:137-150.
    • (1995) J. Cell Biol. , vol.131 , pp. 137-150
    • Mayer, R.1
  • 31
    • 0033616684 scopus 로고    scopus 로고
    • Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier
    • Rao, V.V., et al. 1999. Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier. Pro. Natl Acad. Sci. USA. 96:3900-3905.
    • (1999) Pro. Natl Acad. Sci. USA , vol.96 , pp. 3900-3905
    • Rao, V.V.1
  • 32
    • 0029995238 scopus 로고    scopus 로고
    • Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells
    • Evers, R., et al. 1996. Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells. J. Clin. Invest. 97:1211-1218.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1211-1218
    • Evers, R.1
  • 33
    • 0032936851 scopus 로고    scopus 로고
    • The cell biology of the blood-brain barrier
    • Rubin, L.L., and Staddon, J.M. 1999. The cell biology of the blood-brain barrier. Annu. Rev. Neurosci. 22:11-28.
    • (1999) Annu. Rev. Neurosci. , vol.22 , pp. 11-28
    • Rubin, L.L.1    Staddon, J.M.2
  • 34
    • 0024761936 scopus 로고
    • The mammalian choroid plexus
    • Spector, R., and Johanson, C.E. 1989. The mammalian choroid plexus. Sci. Am. 261:68-74.
    • (1989) Sci. Am. , vol.261 , pp. 68-74
    • Spector, R.1    Johanson, C.E.2
  • 35
    • 0017103247 scopus 로고
    • Structure and function of the choroid plexus and other sites of cerebrospinal fluid formation
    • Mihorat, T.H. 1976. Structure and function of the choroid plexus and other sites of cerebrospinal fluid formation. Int. Rev. Cytol. 47:225-289.
    • (1976) Int. Rev. Cytol. , vol.47 , pp. 225-289
    • Mihorat, T.H.1
  • 36
    • 0031022620 scopus 로고    scopus 로고
    • The choroid plexus epithelium is the site of the organic anion transport protein in the brain
    • Angeletti, R.H., et al. 1997. The choroid plexus epithelium is the site of the organic anion transport protein in the brain. Proc. Natl. Acad. Sci. USA. 94:283-286.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 283-286
    • Angeletti, R.H.1
  • 37
    • 0032967070 scopus 로고    scopus 로고
    • Transepithelial transport of organic anions across the choroid plexus: Possible involvement of organic anion transporter and multidrug resistance-associated protein
    • Nishino, J., et al. 1999. Transepithelial transport of organic anions across the choroid plexus: possible involvement of organic anion transporter and multidrug resistance-associated protein. J. Pharmacol. Exp. Ther. 290:289-294.
    • (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 289-294
    • Nishino, J.1
  • 38
    • 0024454694 scopus 로고
    • Micronutrient homeostasis in mammalian brain and cerebrospinal fluid
    • Spector, R. 1989. Micronutrient homeostasis in mammalian brain and cerebrospinal fluid. J. Neurochem. 53:1667-1674.
    • (1989) J. Neurochem. , vol.53 , pp. 1667-1674
    • Spector, R.1
  • 39
    • 0022558705 scopus 로고
    • Leukotriene C4 transport and metabolism in the central nervous system
    • Spector, R., and Goetzl, E.J. 1986. Leukotriene C4 transport and metabolism in the central nervous system. J. Neurochem. 46:1308-1312.
    • (1986) J. Neurochem. , vol.46 , pp. 1308-1312
    • Spector, R.1    Goetzl, E.J.2
  • 40
    • 0022641352 scopus 로고
    • Transport of prostaglandins and other eicosanoids by the choroid plexus: Its characterization and physiological significance
    • DiBenedetto, F.E., and Bito, L.Z. 1986. Transport of prostaglandins and other eicosanoids by the choroid plexus: its characterization and physiological significance. J. Neurochem. 46:1725-1731.
    • (1986) J. Neurochem. , vol.46 , pp. 1725-1731
    • DiBenedetto, F.E.1    Bito, L.Z.2
  • 41
    • 0015998620 scopus 로고
    • The effects of salicylate and probenecid on the cerebrospinal fluid transport of penicillin, aminosalicyclic acid and iodide
    • Spector, R., and Lorenzo, A.V. 1974. The effects of salicylate and probenecid on the cerebrospinal fluid transport of penicillin, aminosalicyclic acid and iodide. J. Pharmacol, Exp. Ther. 188:55-65.
    • (1974) J. Pharmacol, Exp. Ther. , vol.188 , pp. 55-65
    • Spector, R.1    Lorenzo, A.V.2
  • 42
    • 0028010511 scopus 로고
    • Kinetics of active efflux via choroid plexus of beta-lactam antibiotics from the CSF into the circulation
    • Ogawa, M., Suzuki, H., Sawada, Y., Hanano, M., and Sugiyama, V. 1994. Kinetics of active efflux via choroid plexus of beta-lactam antibiotics from the CSF into the circulation. Am. J. Physiol. 266:R392-R399.
    • (1994) Am. J. Physiol. , vol.266
    • Ogawa, M.1    Suzuki, H.2    Sawada, Y.3    Hanano, M.4    Sugiyama, V.5
  • 43
    • 0024409224 scopus 로고
    • Transport of cefodizime, a novel third generation cephalosporin antibiotic, in isolated rat choroid plexus
    • Nohjoh, T., et al. 1989. Transport of cefodizime, a novel third generation cephalosporin antibiotic, in isolated rat choroid plexus. J. Pharmacol. Exp. Ther. 250:324-328.
    • (1989) J. Pharmacol. Exp. Ther. , vol.250 , pp. 324-328
    • Nohjoh, T.1
  • 44
    • 0024991044 scopus 로고
    • Modeling the enhanced uptake of zidovudine (AZT) into cerebrospinal fluid
    • Sawchuk, R.J., and Hedaya, M.A. 1990. Modeling the enhanced uptake of zidovudine (AZT) into cerebrospinal fluid. I. Effect of probenecid. Pharm. Res. 7:332-338.
    • (1990) I. Effect of Probenecid. Pharm. Res. , vol.7 , pp. 332-338
    • Sawchuk, R.J.1    Hedaya, M.A.2
  • 45
    • 0030977086 scopus 로고    scopus 로고
    • In vivo evidence for carrier-mediated efflux transport of 3́-izido-3́-deoxythymidine and 2́.3́-dideoxyinosine across the blood-brain barrier via a probenecidsensitive transport system
    • Takasawa, K., Terasaki, T., Suzuki, H., and Sugiyama, Y. 1997. In vivo evidence for carrier-mediated efflux transport of 3́-izido-3́-deoxythymidine and 2́.3́-dideoxyinosine across the blood-brain barrier via a probenecidsensitive transport system. J. Pharmacol. Exp. 281:369-375.
    • (1997) J. Pharmacol. Exp. , vol.281 , pp. 369-375
    • Takasawa, K.1    Terasaki, T.2    Suzuki, H.3    Sugiyama, Y.4
  • 46
    • 0028299612 scopus 로고
    • In vitro and in vivo transport of zidovudine (AZT) across the blood brain barrier and the effect of transport inhibitors
    • Masereeuw, K., Jaehde, U., Langemeijer, M.W.E., de Boer, A.G., and Breimer, D.D. 1994. In vitro and in vivo transport of zidovudine (AZT) across the blood brain barrier and the effect of transport inhibitors. Pharm. Res. 11:324-330.
    • (1994) Pharm. Res. , vol.11 , pp. 324-330
    • Masereeuw, K.1    Jaehde, U.2    Langemeijer, M.W.E.3    De Boer, A.G.4    Breimer, D.D.5
  • 47
    • 0027441178 scopus 로고
    • Transport of 2,4,5-trichlorophenoxyacetic acid across the blood cerebrospinal fluid barrier of the rabbit
    • Kim, C.S., and Pritchard, J.B. 1993. Transport of 2,4,5-trichlorophenoxyacetic acid across the blood cerebrospinal fluid barrier of the rabbit. J. Pharmacol. Exp. Ther. 267:751-757.
    • (1993) J. Pharmacol. Exp. Ther. , vol.267 , pp. 751-757
    • Kim, C.S.1    Pritchard, J.B.2
  • 48
    • 0029940587 scopus 로고    scopus 로고
    • Modulation effects of cyclosporine on etoposide pharmacokinetics and CNS distribution in the rat utilizing microdialysis
    • Burgio, D.E., Gosland, M.P., and McNamara, P.J. 1996. Modulation effects of cyclosporine on etoposide pharmacokinetics and CNS distribution in the rat utilizing microdialysis. Biochem. Pharmacol. 51:987-992.
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 987-992
    • Burgio, D.E.1    Gosland, M.P.2    McNamara, P.J.3
  • 49
    • 0029961649 scopus 로고    scopus 로고
    • A new rapid, and economical high-performance liquid chromatographic assay with electrochemical detection for the determination of etoposide (VP-16) in human plasma samples
    • Pérez-Urizar, J., Picazo, Y.F., Navarro-González, B., Flores-Murrieta, F.J., and Castañeda-Hernandez, G. 1996. A new rapid, and economical high-performance liquid chromatographic assay with electrochemical detection for the determination of etoposide (VP-16) in human plasma samples. J. Liq. Chrom. & Rel. Technol. 19:939-947.
    • (1996) J. Liq. Chrom. & Rel. Technol. , vol.19 , pp. 939-947
    • Pérez-Urizar, J.1    Picazo, Y.F.2    Navarro-González, B.3    Flores-Murrieta, F.J.4    Castañeda-Hernandez, G.5
  • 50
    • 0033023585 scopus 로고    scopus 로고
    • Tissue and cell distribution of the multidrug resistance-associated protein (MRP) in mouse intestine and kidney
    • Peng, K.-C., et al. 1999. Tissue and cell distribution of the multidrug resistance-associated protein (MRP) in mouse intestine and kidney. J. Histochem. Cytochem. 47:757-767.
    • (1999) J. Histochem. Cytochem. , vol.47 , pp. 757-767
    • Peng, K.-C.1
  • 51
    • 0032902667 scopus 로고    scopus 로고
    • Toxicity of non-steroidal anti-inflammatory drugs in the large bowel
    • Faucheron, J.L. 1999. Toxicity of non-steroidal anti-inflammatory drugs in the large bowel. Eur. J. Gastroenterol. Hepatol. 11:389-392.
    • (1999) Eur. J. Gastroenterol. Hepatol. , vol.11 , pp. 389-392
    • Faucheron, J.L.1
  • 52
    • 0032534043 scopus 로고    scopus 로고
    • A novel model of inflammatory bowel disease: Mice deficient for the multiple drug resistance gene. Mdr1a, spontaneously develop colitis
    • Panwala, C.M., Jones, J.C., and Viney, J.L. 1998. A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene. Mdr1a, spontaneously develop colitis. J. Immunol 161:5733-5744.
    • (1998) J. Immunol , vol.161 , pp. 5733-5744
    • Panwala, C.M.1    Jones, J.C.2    Viney, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.