Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis

Journal of Neuroscience

Volumn 31, Issue 19, 2011, Pages 7049-7059

  Terwel, Dick ^a   Steffensen, Knut R ^b   Verghese, Philip B ^c   Kummer, Markus P ^a   Gustafsson, Jan Åke ^b   Holtzman, David M ^c   Heneka, Michael T ^a  

^a UNIVERSITY OF BONN   (Germany)

^b KAROLINSKA INSTITUTE   (Sweden)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; LIVER X RECEPTOR ALPHA; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; AUTOPSY; BLOOD BRAIN BARRIER; CONTROLLED STUDY; CULTURE MEDIUM; DISEASE MODEL; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG PENETRATION; LEARNING; MACROGLIA; MAZE TEST; MICROGLIA; MOUSE; NONHUMAN; OPEN FIELD BEHAVIOR; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; RECEPTOR UPREGULATION; SPATIAL DISCRIMINATION;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANALYSIS OF VARIANCE; ANIMALS; APOLIPOPROTEINS E; ASTROCYTES; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN; CULTURE MEDIA, CONDITIONED; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYDROCARBONS, FLUORINATED; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; MAZE LEARNING; MICE; MICE, TRANSGENIC; MICROGLIA; ORPHAN NUCLEAR RECEPTORS; PHAGOCYTOSIS; SULFONAMIDES;

EID: 79956311751     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6546-10.2011     Document Type: Article

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