Parkin null cortical neuronal/glial cultures are resistant to amyloid-β1-42 toxicity: A role for autophagy?

Journal of Alzheimer's Disease

Volumn 32, Issue 1, 2012, Pages 57-76

  Solano, Rosa M ^a   Casarejos, Maria J ^a   Gómez, Ana ^a   Perucho, Juan ^a   De Yébenes, Justo García ^a   Mena, Maria A ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

Alzheimer's disease; apoptosis; autophagy lysosomal pathway; chaperones; cortical neuron glial cultures; glutathione; Park 2 gene; ubiquitin proteasome system

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; GLUTATHIONE; HEAT SHOCK PROTEIN 70; LIGHT CHAIN 3 PROTEIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYOSIN LIGHT CHAIN; OLIGOMERIC AMYLOID BETA PROTEIN[1-42]; PARKIN; PROTEASOME; PROTEIN KINASE B; RECOMBINANT PROTEIN; TAU PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTOSIS; AUTOPHAGY; BRAIN CELL; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GLIA CELL; IMMUNOREACTIVITY; LIGHT CHAIN; MICROGLIA; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UBIQUITINATION; WESTERN BLOTTING; WILD TYPE;

EID: 84867565502     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2012-120406     Document Type: Article

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