-
1
-
-
0035203662
-
Key factors in Alzheimer's disease: Beta-amyloid precursor protein processing, metabolism and intraneuronal transport
-
T.A. Bayer, O. Wirths, K. Majtenyi, T. Hartmann, G. Multhaup, and K. Beyreuther Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport Brain Pathol 11 1 2001 1 11
-
(2001)
Brain Pathol
, vol.11
, Issue.1
, pp. 1-11
-
-
Bayer, T.A.1
Wirths, O.2
Majtenyi, K.3
Hartmann, T.4
Multhaup, G.5
Beyreuther, K.6
-
2
-
-
0028207907
-
Amyloid beta peptide induces necrosis rather than apoptosis
-
C. Behl, J.B. Davis, F.G. Klier, and D. Schubert Amyloid beta peptide induces necrosis rather than apoptosis Brain Res 645 1/2 1994 253 264
-
(1994)
Brain Res
, vol.645
, Issue.1-2
, pp. 253-264
-
-
Behl, C.1
Davis, J.B.2
Klier, F.G.3
Schubert, D.4
-
3
-
-
0035378322
-
Functional mitochondria are required for amyloid beta-mediated neurotoxicity
-
S.M. Cardoso, S. Santos, R.H. Swerdlow, and C.R. Oliveira Functional mitochondria are required for amyloid beta-mediated neurotoxicity FASEB J 15 8 2001 1439 1451
-
(2001)
FASEB J
, vol.15
, Issue.8
, pp. 1439-1451
-
-
Cardoso, S.M.1
Santos, S.2
Swerdlow, R.H.3
Oliveira, C.R.4
-
4
-
-
0033542077
-
Binding of gelsolin, a secretory protein, to amyloid beta-protein
-
V.P. Chauhan, I. Ray, A. Chauhan, and H.M. Wisniewski Binding of gelsolin, a secretory protein, to amyloid beta-protein Biochem Biophys Res Commun 258 2 1999 241 246
-
(1999)
Biochem Biophys Res Commun
, vol.258
, Issue.2
, pp. 241-246
-
-
Chauhan, V.P.1
Ray, I.2
Chauhan, A.3
Wisniewski, H.M.4
-
5
-
-
0031902295
-
Alzheimer's disease: Etiologies, pathophysiology, cognitive reserve, and treatment opportunities
-
J.L. Cummings, H.V. Vinters, G.M. Cole, and Z.S. Khachaturian Alzheimer's disease: etiologies, pathophysiology, cognitive reserve, and treatment opportunities Neurology 51 Suppl. 1 1998 2 17
-
(1998)
Neurology
, vol.51
, Issue.1 SUPPL.
, pp. 2-17
-
-
Cummings, J.L.1
Vinters, H.V.2
Cole, G.M.3
Khachaturian, Z.S.4
-
6
-
-
0032774329
-
Bcl-2 protects against FCCP-induced apoptosis and mitochondrial membrane potential depolarization in PC12 cells
-
G. Dispersyn, R. Nuydens, R. Connors, M. Borgers, and H. Geerts Bcl-2 protects against FCCP-induced apoptosis and mitochondrial membrane potential depolarization in PC12 cells Biochim Biophys Acta 1428 2/3 1999 357 371
-
(1999)
Biochim Biophys Acta
, vol.1428
, Issue.2-3
, pp. 357-371
-
-
Dispersyn, G.1
Nuydens, R.2
Connors, R.3
Borgers, M.4
Geerts, H.5
-
7
-
-
0032959847
-
Neuroprotective effects of gelsolin during murine stroke
-
M. Endres, K. Fink, J. Zhu, N.E. Stagliano, V. Bondada, and J.W. Geddes Neuroprotective effects of gelsolin during murine stroke J Clin Invest 103 3 1999 347 354
-
(1999)
J Clin Invest
, vol.103
, Issue.3
, pp. 347-354
-
-
Endres, M.1
Fink, K.2
Zhu, J.3
Stagliano, N.E.4
Bondada, V.5
Geddes, J.W.6
-
8
-
-
0035883163
-
Gelsolin functions as a metastasis suppressor in B16-BL6 mouse melanoma cells and requirement of the carboxyl-terminus for its effect
-
H. Fujita, F. Okada, J. Hamada, M. Hosokawa, T. Moriuchi, and R.C. Koya Gelsolin functions as a metastasis suppressor in B16-BL6 mouse melanoma cells and requirement of the carboxyl-terminus for its effect Int J Cancer 93 6 2001 773 780
-
(2001)
Int J Cancer
, vol.93
, Issue.6
, pp. 773-780
-
-
Fujita, H.1
Okada, F.2
Hamada, J.3
Hosokawa, M.4
Moriuchi, T.5
Koya, R.C.6
-
9
-
-
0030807917
-
The actin-severing protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons
-
K. Furukawa, W. Fu, Y. Li, W. Witke, D.J. Kwiatkowski, and M.P. Mattson The actin-severing protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons J Neurosci 17 21 1997 8178 8186
-
(1997)
J Neurosci
, vol.17
, Issue.21
, pp. 8178-8186
-
-
Furukawa, K.1
Fu, W.2
Li, Y.3
Witke, W.4
Kwiatkowski, D.J.5
Mattson, M.P.6
-
10
-
-
0033942156
-
Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis
-
E. Gottlieb, M.G. Vander Heider, and C.B. Thompson Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis Mol Cell Biol 20 15 2000 5680 5689
-
(2000)
Mol Cell Biol
, vol.20
, Issue.15
, pp. 5680-5689
-
-
Gottlieb, E.1
Vander Heider, M.G.2
Thompson, C.B.3
-
11
-
-
0033740610
-
Mechanisms of beta-amyloid neurotoxicity: Perspectives of pharmacotherapy
-
T. Harkany, I. Abraham, C. Konya, C. Nyakas, M. Zarandi, and B. Penke Mechanisms of beta-amyloid neurotoxicity: perspectives of pharmacotherapy Rev Neurosci 11 4 2000 329 382
-
(2000)
Rev Neurosci
, vol.11
, Issue.4
, pp. 329-382
-
-
Harkany, T.1
Abraham, I.2
Konya, C.3
Nyakas, C.4
Zarandi, M.5
Penke, B.6
-
12
-
-
0037693763
-
Gelsolin domains 4-6 in active, actin-free conformation identifies sites of regulatory calcium ions
-
S. Kolappan, J.T. Gooch, A.G. Weeds, and P.J. McLaughlin Gelsolin domains 4-6 in active, actin-free conformation identifies sites of regulatory calcium ions J Mol Biol 329 1 2003 85 92
-
(2003)
J Mol Biol
, vol.329
, Issue.1
, pp. 85-92
-
-
Kolappan, S.1
Gooch, J.T.2
Weeds, A.G.3
McLaughlin, P.J.4
-
13
-
-
0034685808
-
Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release
-
R.C. Koya, H. Fujita, S. Shimizu, M. Ohtsu, M. Takimoto, and Y. Tsujimoto Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release J Biol Chem 275 20 2000 15343 15349
-
(2000)
J Biol Chem
, vol.275
, Issue.20
, pp. 15343-15349
-
-
Koya, R.C.1
Fujita, H.2
Shimizu, S.3
Ohtsu, M.4
Takimoto, M.5
Tsujimoto, Y.6
-
14
-
-
0034609764
-
Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC
-
H. Kusano, S. Shimizu, R.C. Koya, H. Fujita, S. Kamada, and N. Kuzumaki Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC Oncogene 19 42 2000 4807 4814
-
(2000)
Oncogene
, vol.19
, Issue.42
, pp. 4807-4814
-
-
Kusano, H.1
Shimizu, S.2
Koya, R.C.3
Fujita, H.4
Kamada, S.5
Kuzumaki, N.6
-
15
-
-
0023883135
-
Genomic organization and biosynthesis of secreted and cytoplasmic forms of gelsolin
-
D.J. Kwiatkowski, R. Mehl, and H.L. Yin Genomic organization and biosynthesis of secreted and cytoplasmic forms of gelsolin J Cell Biol 106 2 1988 375 384
-
(1988)
J Cell Biol
, vol.106
, Issue.2
, pp. 375-384
-
-
Kwiatkowski, D.J.1
Mehl, R.2
Yin, H.L.3
-
16
-
-
0022487183
-
Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain
-
D.J. Kwiatkowski, T.P. Stossel, S.H. Orkin, J.E. Mole, H.R. Colten, and H.L. Yin Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain Nature 323 6087 1986 455 458
-
(1986)
Nature
, vol.323
, Issue.6087
, pp. 455-458
-
-
Kwiatkowski, D.J.1
Stossel, T.P.2
Orkin, S.H.3
Mole, J.E.4
Colten, H.R.5
Yin, H.L.6
-
17
-
-
0028971093
-
Beta-Amyloid-induced toxicity in rat hippocampal cells: In vitro evidence for the involvement of free radicals
-
A.M. Manelli, and P.S. Puttfarcken Beta-Amyloid-induced toxicity in rat hippocampal cells: in vitro evidence for the involvement of free radicals Brain Res Bull 38 6 1995 569 576
-
(1995)
Brain Res Bull
, vol.38
, Issue.6
, pp. 569-576
-
-
Manelli, A.M.1
Puttfarcken, P.S.2
-
18
-
-
0031760611
-
Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease
-
E. Masliah, M. Mallory, M. Alford, S. Tanaka, and L.A. Hansen Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease J Neuropathol Exp Neurol 57 11 1998 1041 1052
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, Issue.11
, pp. 1041-1052
-
-
Masliah, E.1
Mallory, M.2
Alford, M.3
Tanaka, S.4
Hansen, L.A.5
-
19
-
-
0034672421
-
Alzheimer's disease: A dysfunction of the amyloid precursor protein (1)
-
R.L. Neve, D.L. McPhie, and Y. Chen Alzheimer's disease: a dysfunction of the amyloid precursor protein (1) Brain Res 886 1/2 2000 54 66
-
(2000)
Brain Res
, vol.886
, Issue.1-2
, pp. 54-66
-
-
Neve, R.L.1
McPhie, D.L.2
Chen, Y.3
-
20
-
-
0030829514
-
Inhibition of apoptosis by the actin-regulatory protein gelsolin
-
M. Ohtsu, N. Sakai, H. Fujita, M. Kashiwagi, S. Gasa, and S. Shimizu Inhibition of apoptosis by the actin-regulatory protein gelsolin EMBO J 16 15 1997 4650 4656
-
(1997)
EMBO J
, vol.16
, Issue.15
, pp. 4650-4656
-
-
Ohtsu, M.1
Sakai, N.2
Fujita, H.3
Kashiwagi, M.4
Gasa, S.5
Shimizu, S.6
-
21
-
-
0034660602
-
Glutamine synthetase, hemoglobin alpha-chain, and macrophage migration inhibitory factor binding to amyloid beta-protein: Their identification in rat brain by a novel affinity chromatography and in Alzheimer's disease brain by immunoprecipitation
-
R. Oyama, H. Yamamoto, and K. Titani Glutamine synthetase, hemoglobin alpha-chain, and macrophage migration inhibitory factor binding to amyloid beta-protein: their identification in rat brain by a novel affinity chromatography and in Alzheimer's disease brain by immunoprecipitation Biochim Biophys Acta 1479 1/2 2000 91 102
-
(2000)
Biochim Biophys Acta
, vol.1479
, Issue.1-2
, pp. 91-102
-
-
Oyama, R.1
Yamamoto, H.2
Titani, K.3
-
22
-
-
0031037086
-
Specific modulation of the fusogenic properties of the Alzheimer beta-amyloid peptide by apolipoprotein e isoforms
-
T. Pillot, M. Goethals, B. Vanloo, L. Lins, R. Brasseur, and J. Vandekerckhove Specific modulation of the fusogenic properties of the Alzheimer beta-amyloid peptide by apolipoprotein E isoforms Eur J Biochem 243 3 1997 650 659
-
(1997)
Eur J Biochem
, vol.243
, Issue.3
, pp. 650-659
-
-
Pillot, T.1
Goethals, M.2
Vanloo, B.3
Lins, L.4
Brasseur, R.5
Vandekerckhove, J.6
-
23
-
-
9044243405
-
Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons
-
J.H. Prehn, V.P. Bindokas, J. Jordan, M.F. Galindo, G.D. Ghadge, and R.P. Roos Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons Mol Pharmacol 49 2 1996 319 328
-
(1996)
Mol Pharmacol
, vol.49
, Issue.2
, pp. 319-328
-
-
Prehn, J.H.1
Bindokas, V.P.2
Jordan, J.3
Galindo, M.F.4
Ghadge, G.D.5
Roos, R.P.6
-
24
-
-
0033988752
-
Gelsolin inhibits the fibrillization of amyloid beta-protein, and also defibrillizes its preformed fibrils
-
I. Ray, A. Chauhan, J. Wegiel, and V.P. Chauhan Gelsolin inhibits the fibrillization of amyloid beta-protein, and also defibrillizes its preformed fibrils Brain Res 853 2 2000 344 351
-
(2000)
Brain Res
, vol.853
, Issue.2
, pp. 344-351
-
-
Ray, I.1
Chauhan, A.2
Wegiel, J.3
Chauhan, V.P.4
-
25
-
-
0031791135
-
Binding of amyloid beta-protein to intracellular brain proteins in rat and human
-
I. Ray, A. Chauhan, H.M. Wisniewski, J. Wegiel, K.S. Kim, and V.P. Chauhan Binding of amyloid beta-protein to intracellular brain proteins in rat and human Neurochem Res 23 10 1998 1277 1282
-
(1998)
Neurochem Res
, vol.23
, Issue.10
, pp. 1277-1282
-
-
Ray, I.1
Chauhan, A.2
Wisniewski, H.M.3
Wegiel, J.4
Kim, K.S.5
Chauhan, V.P.6
-
26
-
-
0033521081
-
Domain movement in gelsolin: A calcium-activated switch
-
R.C. Robinson, M. Mejillano, V.P. Le, L.D. Burtnick, H.L. Yin, and S. Choe Domain movement in gelsolin: a calcium-activated switch Science 286 5446 1999 1939 1942
-
(1999)
Science
, vol.286
, Issue.5446
, pp. 1939-1942
-
-
Robinson, R.C.1
Mejillano, M.2
Le V., P.3
Burtnick, L.D.4
Yin, H.L.5
Choe, S.6
-
27
-
-
0034327232
-
Bilirubin and amyloid-beta peptide induce cytochrome c release through mitochondrial membrane permeabilization
-
C.M. Rodrigues, S. Sola, R. Silva, and D. Brites Bilirubin and amyloid-beta peptide induce cytochrome c release through mitochondrial membrane permeabilization Mol Med 6 11 2000 936 946
-
(2000)
Mol Med
, vol.6
, Issue.11
, pp. 936-946
-
-
Rodrigues, C.M.1
Sola, S.2
Silva, R.3
Brites, D.4
-
28
-
-
0030329641
-
Interaction of transthyretin with amyloid beta-protein: Binding and inhibition of amyloid formation
-
A.L. Schwarzman, and D. Goldgaber Interaction of transthyretin with amyloid beta-protein: binding and inhibition of amyloid formation Ciba Found Symp 199 1996 146 160
-
(1996)
Ciba Found Symp
, vol.199
, pp. 146-160
-
-
Schwarzman, A.L.1
Goldgaber, D.2
-
29
-
-
0001027292
-
Gelsolin, a multifunctional actin regulatory protein
-
H.Q. Sun, M. Yamamoto, M. Mejillano, and H.L. Yin Gelsolin, a multifunctional actin regulatory protein J Biol Chem 274 47 1999 33179 33182
-
(1999)
J Biol Chem
, vol.274
, Issue.47
, pp. 33179-33182
-
-
Sun, H.Q.1
Yamamoto, M.2
Mejillano, M.3
Yin, H.L.4
-
30
-
-
0031214063
-
Amyloid beta-protein induces necrotic cell death mediated by ICE cascade in PC12 cells
-
A. Suzuki Amyloid beta-protein induces necrotic cell death mediated by ICE cascade in PC12 cells Exp Cell Res 234 2 1997 507 511
-
(1997)
Exp Cell Res
, vol.234
, Issue.2
, pp. 507-511
-
-
Suzuki, A.1
-
31
-
-
0027756675
-
Gelsolin is localized in neuronal growth cones
-
J. Tanaka, M. Kira, and K. Sobue Gelsolin is localized in neuronal growth cones Brain Res Dev Brain Res 76 2 1993 268 271
-
(1993)
Brain Res Dev Brain Res
, vol.76
, Issue.2
, pp. 268-271
-
-
Tanaka, J.1
Kira, M.2
Sobue, K.3
-
32
-
-
0033860546
-
Therapeutic approaches to Alzheimer's disease
-
E.D. Thorsett, and L.H. Latimer Therapeutic approaches to Alzheimer's disease Curr Opin Chem Biol 4 4 2000 377 382
-
(2000)
Curr Opin Chem Biol
, vol.4
, Issue.4
, pp. 377-382
-
-
Thorsett, E.D.1
Latimer, L.H.2
-
33
-
-
0030757386
-
A novel gelsolin isoform expressed by oligodendrocytes in the central nervous system
-
D.A. Vouyiouklis, and P.J. Brophy A novel gelsolin isoform expressed by oligodendrocytes in the central nervous system J Neurochem 69 3 1997 995 1005
-
(1997)
J Neurochem
, vol.69
, Issue.3
, pp. 995-1005
-
-
Vouyiouklis, D.A.1
Brophy, P.J.2
-
34
-
-
0036392348
-
Dissecting the gelsolin-polyphosphoinositide interaction and engineering of a polyphosphoinositide-sensitive gelsolin c-terminal half protein
-
W. Xian, and P.A. Janmey Dissecting the gelsolin-polyphosphoinositide interaction and engineering of a polyphosphoinositide-sensitive gelsolin c-terminal half protein J Mol Biol 322 4 2002 755 771
-
(2002)
J Mol Biol
, vol.322
, Issue.4
, pp. 755-771
-
-
Xian, W.1
Janmey, P.A.2
|