Parkin deficiency increases the resistance of midbrain neurons and glia to mild proteasome inhibition: The role of autophagy and glutathione homeostasis

Journal of Neurochemistry

Volumn 110, Issue 5, 2009, Pages 1523-1537

  Casarejos, Maria J ^a   Solano, Rosa M ^a   Rodriguez Navarro, José A ^a   Gómez, Ana ^a   Perucho, Juan ^a   Castaño, Jose G ^b   De Yébenes, Justo García ^a   Mena, Maria A ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Autophagy lysosomal pathway; Chaperones; DJ 1; Dopamine neurons; Glial cells; Parkinson's disease

Indexed keywords

BUTHIONINE SULFOXIMINE; C TERMINAL HSC INTERACTING PROTEIN; CHAPERONE; DJ 1 PROTEIN; EPOXOMICIN; GLUTATHIONE; HEAT SHOCK PROTEIN 70; PROTEASOME; PROTEIN BAX; PROTEIN BCL 2; PROTEIN SERINE THREONINE KINASE; TAU PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELL DEATH; CELL GROWTH; CELL PROTECTION; CELL STRESS; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GLIA; HOMEOSTASIS; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MESENCEPHALON; MOUSE; NERVE CELL; NERVE CELL CULTURE; NONHUMAN; PARKIN DEFICIENCY; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN PHOSPHORYLATION; WILD TYPE;

ANIMALS; AUTOPHAGY; CELL LINE, TUMOR; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; HOMEOSTASIS; HUMANS; MESENCEPHALON; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUROGLIA; NEURONS; OLIGOPEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITIN-PROTEIN LIGASES;

MUS;

EID: 68949208061     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06248.x     Document Type: Article

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